Guide to the Human Genome
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Search of human proteins with 228480211

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|228480211 four and a half LIM domains 1 isoform 1 [Homo
sapiens]
         (323 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]   721   0.0  
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]   525   e-149
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]   525   e-149
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]   525   e-149
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]   525   e-149
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]    525   e-149
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]   387   e-108
gi|87159836 four and a half LIM domains 2 [Homo sapiens]              286   2e-77
gi|87159834 four and a half LIM domains 2 [Homo sapiens]              286   2e-77
gi|42403575 four and a half LIM domains 2 [Homo sapiens]              286   2e-77
gi|87159832 four and a half LIM domains 2 [Homo sapiens]              286   2e-77
gi|54112385 four and a half LIM domains 3 [Homo sapiens]              259   2e-69
gi|30410801 activator of cAMP-responsive element modulator (CREM...   252   4e-67
gi|170932518 paxillin isoform 3 [Homo sapiens]                        120   1e-27
gi|170932516 paxillin isoform 2 [Homo sapiens]                        120   1e-27
gi|170932514 paxillin isoform 1 [Homo sapiens]                        120   1e-27
gi|221316659 leupaxin isoform 1 [Homo sapiens]                        107   1e-23
gi|4758670 leupaxin isoform 2 [Homo sapiens]                          107   1e-23
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   103   2e-22
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   103   2e-22
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   103   2e-22
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   103   2e-22
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   103   2e-22
gi|109638745 transforming growth factor beta 1 induced transcrip...   101   8e-22
gi|21361591 transforming growth factor beta 1 induced transcript...   101   8e-22
gi|38524620 prickle-like 2 [Homo sapiens]                             101   1e-21
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]             99   5e-21
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              99   5e-21
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]       96   4e-20
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]       96   4e-20

>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
          Length = 323

 Score =  721 bits (1861), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHP 240
           WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHP
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHP 240

Query: 241 VSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVK 300
           VSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVK
Sbjct: 241 VSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVK 300

Query: 301 APVWWPMKDNPGTTTASTAKNAP 323
           APVWWPMKDNPGTTTASTAKNAP
Sbjct: 301 APVWWPMKDNPGTTTASTAKNAP 323


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  525 bits (1351), Expect = e-149
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230



 Score =  150 bits (380), Expect = 1e-36
 Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
           DCF C  C + +    F    + +YCV C++   AK C  C   IT  G     + Y+ Q
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 243

Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
            WH  CF C  CS  LA +RF   ++Q YC DC K
Sbjct: 244 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  525 bits (1351), Expect = e-149
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230



 Score =  150 bits (380), Expect = 1e-36
 Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
           DCF C  C + +    F    + +YCV C++   AK C  C   IT  G     + Y+ Q
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 243

Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
            WH  CF C  CS  LA +RF   ++Q YC DC K
Sbjct: 244 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score =  525 bits (1351), Expect = e-149
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 30  MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 89

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 90  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 209

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 210 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 259



 Score =  150 bits (380), Expect = 1e-36
 Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 95  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 154

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 155 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 212

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
           DCF C  C + +    F    + +YCV C++   AK C  C   IT  G     + Y+ Q
Sbjct: 213 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 272

Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
            WH  CF C  CS  LA +RF   ++Q YC DC K
Sbjct: 273 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 307



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 212 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 271

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 272 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 308


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score =  525 bits (1351), Expect = e-149
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 17  MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 77  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 246



 Score =  150 bits (380), Expect = 1e-36
 Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 82  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 141

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 142 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 199

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
           DCF C  C + +    F    + +YCV C++   AK C  C   IT  G     + Y+ Q
Sbjct: 200 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 259

Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
            WH  CF C  CS  LA +RF   ++Q YC DC K
Sbjct: 260 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 294



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 258

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 259 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  525 bits (1351), Expect = e-149
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230



 Score =  150 bits (380), Expect = 1e-36
 Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
           DCF C  C + +    F    + +YCV C++   AK C  C   IT  G     + Y+ Q
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 243

Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
            WH  CF C  CS  LA +RF   ++Q YC DC K
Sbjct: 244 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI   G  S  V Y+ 
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
           + WHD CF C KC   LAN+ FV    ++ C  C  +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279


>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
          Length = 194

 Score =  387 bits (994), Expect = e-108
 Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 178
           VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK +    + +  +D
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180

Query: 179 QP 180
            P
Sbjct: 181 NP 182



 Score =  109 bits (272), Expect = 4e-24
 Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)

Query: 66  FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125
           F C  C  PL  + +V KD    C KC  +  +  C  C K I A  + V YK   WH  
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183
           CF C+ C   +   +F  K     C  C   + +  C  C KAI +G   + Y+   WH 
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224
           DCF C  C + +    F    + +YCV C++   AK C  C
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165



 Score =  100 bits (249), Expect = 2e-21
 Identities = 67/206 (32%), Positives = 87/206 (42%), Gaps = 25/206 (12%)

Query: 127 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHAD 184
           F C  C+  +    +  K     C+ C +   A  CV+C K I   S  + Y+++ WH  
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG-------KRTVSRV 237
           CF C  C   LA + F A +++  C  C     + KC GC   I         K TV   
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 238 SHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPG 297
                   K  +  G   P              G +  C +     + K+         G
Sbjct: 125 DCFTCSNCKQVIGTGSFFP-------------KGEDFYCVTCHETKFAKH---CVKCNKG 168

Query: 298 LVKAPVWWPMKDNPGTTTASTAKNAP 323
           LVKAPVWWPMKDNPGTTTASTAKNAP
Sbjct: 169 LVKAPVWWPMKDNPGTTTASTAKNAP 194



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 14/46 (30%), Positives = 23/46 (50%)

Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPI 228
           A+ F C  C   L G+++   +  + C+ C+  F A  C  C+ PI
Sbjct: 2   AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI 47


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  286 bits (731), Expect = 2e-77
 Identities = 116/230 (50%), Positives = 162/230 (70%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230



 Score =  162 bits (409), Expect = 5e-40
 Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C   I+  G    I+++++ 
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
           WH DCF C  CS  L G+ F    D   C DC K+
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  286 bits (731), Expect = 2e-77
 Identities = 116/230 (50%), Positives = 162/230 (70%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230



 Score =  162 bits (409), Expect = 5e-40
 Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C   I+  G    I+++++ 
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
           WH DCF C  CS  L G+ F    D   C DC K+
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  286 bits (731), Expect = 2e-77
 Identities = 116/230 (50%), Positives = 162/230 (70%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230



 Score =  162 bits (409), Expect = 5e-40
 Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C   I+  G    I+++++ 
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
           WH DCF C  CS  L G+ F    D   C DC K+
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278


>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  286 bits (731), Expect = 2e-77
 Identities = 116/230 (50%), Positives = 162/230 (70%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230



 Score =  162 bits (409), Expect = 5e-40
 Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C   I+  G    I+++++ 
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
           WH DCF C  CS  L G+ F    D   C DC K+
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score =  259 bits (662), Expect = 2e-69
 Identities = 105/230 (45%), Positives = 148/230 (64%)

Query: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
           M+E FDC  C + L G+KY+Q D    C+ C+D   ANTC EC++ IG DS+E+ Y++R 
Sbjct: 1   MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           +H+ CFRC +C   LA+E F  +D+++LCN C     S +C  C + ++ G + +EY G 
Sbjct: 61  FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
            WH+ CF CS C+Q +G+ SF P     YCV C+E KFA  C +C+K +T GG+TY+DQP
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           WH +C VC  C   LAGQ+FT+ ++  YCV C+    A KC+ CK PI G
Sbjct: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVG 230



 Score =  140 bits (353), Expect = 2e-33
 Identities = 64/212 (30%), Positives = 99/212 (46%), Gaps = 6/212 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+  L  + +  +D    C  C+    ++ C  C + +   S+++ Y  + WH+ 
Sbjct: 66  FRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEH 125

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF C+ C  PL + +FV       C  C   + +P+C  C K +  G   V Y+   WH+
Sbjct: 126 CFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQG--GVTYRDQPWHR 183

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
           +C  C+ C+  +    F  + ED YCV C    FA  C  C + I   G    ++++D+ 
Sbjct: 184 ECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRH 243

Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDC 212
           WH +CF C  CS  L GQ F    DQ  C  C
Sbjct: 244 WHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275



 Score =  100 bits (248), Expect = 2e-21
 Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  PL  + +V   G H C+ C++   A  C  C K +      V Y+++ WH  
Sbjct: 127 FLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG--VTYRDQPWHRE 184

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA--GDQNVEYKGTVW 122
           C  C  C  PLA + F ++D    C  C     +PKC  C + IV   G + V ++   W
Sbjct: 185 CLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHW 244

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
           H +CF+C+ C   +    F P G+   C  C +
Sbjct: 245 HHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277


>gi|30410801 activator of cAMP-responsive element modulator (CREM)
           in testis [Homo sapiens]
          Length = 284

 Score =  252 bits (643), Expect = 4e-67
 Identities = 106/226 (46%), Positives = 142/226 (62%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C YC   L GKKYV KD    C+ C+D+  +N C EC+KPI +DSK++ YK+R WH+ 
Sbjct: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
           CF+C KC H L  + F AKD ++LC +C + E S KC  C + I+ G + +E+KG  WH+
Sbjct: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125

Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 184
            CF C NC+Q IGT     K    YCV C E +FA +C  C K ITSGGIT+ DQ WH +
Sbjct: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185

Query: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           CF+C  C K L  ++F + +D  +C+DCY +  A KC  C  PI+G
Sbjct: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISG 231



 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60
           E F C  CR  L  ++++ +D +  C+ C++   AN CV C KPI     +K + +++  
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
           WH  CF C KC   L  + F+ ++ +I C KC +  D+
Sbjct: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  120 bits (302), Expect = 1e-27
 Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +  + + ++DG   C K +    +  C  C  PI    K V   +R WH
Sbjct: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 270

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F CA+C      E F  KD K  C K      +PKC GC +AI+  +  +    T+W
Sbjct: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 328

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
           H +CF C  C      GSFF      YC   +  +    C  C K IT   IT   + +H
Sbjct: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388

Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
            + FVC  C K+L    F    D+ YC +C+
Sbjct: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 419



 Score =  101 bits (251), Expect = 1e-21
 Identities = 60/203 (29%), Positives = 84/203 (41%), Gaps = 6/203 (2%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    + V    + WH   F C  C   + +  F  +D +  C K      SP
Sbjct: 191 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ V      WH + F C+ C    G   F  K    YC   +   FA
Sbjct: 249 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306

Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
             C  C +AI    I+  +  WH +CFVC  C        F   + Q YC   Y      
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366

Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
            C+GC+ PITG+    +++  HP
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHP 389



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 22/82 (26%), Positives = 28/82 (34%), Gaps = 28/82 (34%)

Query: 187 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 220
           VC  C K +AGQ  TA+                          + Q YC   Y N  + +
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249

Query: 221 CAGCKNPITGK--RTVSRVSHP 240
           C  C  PI  K    + R  HP
Sbjct: 250 CYYCNGPILDKVVTALDRTWHP 271


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  120 bits (302), Expect = 1e-27
 Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +  + + ++DG   C K +    +  C  C  PI    K V   +R WH
Sbjct: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 403

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F CA+C      E F  KD K  C K      +PKC GC +AI+  +  +    T+W
Sbjct: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 461

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
           H +CF C  C      GSFF      YC   +  +    C  C K IT   IT   + +H
Sbjct: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521

Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
            + FVC  C K+L    F    D+ YC +C+
Sbjct: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 552



 Score =  101 bits (251), Expect = 1e-21
 Identities = 60/203 (29%), Positives = 84/203 (41%), Gaps = 6/203 (2%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    + V    + WH   F C  C   + +  F  +D +  C K      SP
Sbjct: 324 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ V      WH + F C+ C    G   F  K    YC   +   FA
Sbjct: 382 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439

Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
             C  C +AI    I+  +  WH +CFVC  C        F   + Q YC   Y      
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499

Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
            C+GC+ PITG+    +++  HP
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHP 522



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 22/82 (26%), Positives = 28/82 (34%), Gaps = 28/82 (34%)

Query: 187 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 220
           VC  C K +AGQ  TA+                          + Q YC   Y N  + +
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382

Query: 221 CAGCKNPITGK--RTVSRVSHP 240
           C  C  PI  K    + R  HP
Sbjct: 383 CYYCNGPILDKVVTALDRTWHP 404


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  120 bits (302), Expect = 1e-27
 Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +  + + ++DG   C K +    +  C  C  PI    K V   +R WH
Sbjct: 380 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 437

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F CA+C      E F  KD K  C K      +PKC GC +AI+  +  +    T+W
Sbjct: 438 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 495

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
           H +CF C  C      GSFF      YC   +  +    C  C K IT   IT   + +H
Sbjct: 496 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 555

Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
            + FVC  C K+L    F    D+ YC +C+
Sbjct: 556 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 586



 Score =  101 bits (251), Expect = 1e-21
 Identities = 60/203 (29%), Positives = 84/203 (41%), Gaps = 6/203 (2%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    + V    + WH   F C  C   + +  F  +D +  C K      SP
Sbjct: 358 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 415

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ V      WH + F C+ C    G   F  K    YC   +   FA
Sbjct: 416 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473

Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
             C  C +AI    I+  +  WH +CFVC  C        F   + Q YC   Y      
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533

Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
            C+GC+ PITG+    +++  HP
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHP 556



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 22/82 (26%), Positives = 28/82 (34%), Gaps = 28/82 (34%)

Query: 187 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 220
           VC  C K +AGQ  TA+                          + Q YC   Y N  + +
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416

Query: 221 CAGCKNPITGK--RTVSRVSHP 240
           C  C  PI  K    + R  HP
Sbjct: 417 CYYCNGPILDKVVTALDRTWHP 438


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score =  107 bits (267), Expect = 1e-23
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 236

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
           H +CF C +C     TGSFF      +C   +  +    C  C + IT   I+     +H
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354

Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
            + FVC  C  +L+   F    D+ YC  C+
Sbjct: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385



 Score =  103 bits (258), Expect = 2e-22
 Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 4/192 (2%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272

Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
             C  CN+ +    ++  D  WH +CFVC  C    +   F  ++ + +C   Y +    
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332

Query: 220 KCAGCKNPITGK 231
            C GC  PITG+
Sbjct: 333 LCHGCGQPITGR 344



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
           HC  C K I    I    Q WH + FVC  C +++    F       YC + Y    + +
Sbjct: 156 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 215

Query: 221 CAGCKNPITGK--RTVSRVSHP 240
           CA C  PI  K    +++  HP
Sbjct: 216 CAYCAAPILDKVLTAMNQTWHP 237


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score =  107 bits (267), Expect = 1e-23
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 174 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 231

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 232 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 289

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
           H +CF C +C     TGSFF      +C   +  +    C  C + IT   I+     +H
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 349

Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
            + FVC  C  +L+   F    D+ YC  C+
Sbjct: 350 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 380



 Score =  103 bits (258), Expect = 2e-22
 Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 4/192 (2%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 152 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 210 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267

Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
             C  CN+ +    ++  D  WH +CFVC  C    +   F  ++ + +C   Y +    
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327

Query: 220 KCAGCKNPITGK 231
            C GC  PITG+
Sbjct: 328 LCHGCGQPITGR 339



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 233 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 290

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 291 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 348

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 349 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
           HC  C K I    I    Q WH + FVC  C +++    F       YC + Y    + +
Sbjct: 151 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 210

Query: 221 CAGCKNPITGK--RTVSRVSHP 240
           CA C  PI  K    +++  HP
Sbjct: 211 CAYCAAPILDKVLTAMNQTWHP 232


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  103 bits (258), Expect = 2e-22
 Identities = 65/232 (28%), Positives = 91/232 (39%), Gaps = 12/232 (5%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C        + + +G   C   F    A  C +C + I    + +   N  WH  
Sbjct: 36  FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
           CFRC  C   LA+  FV    + LC  C  RE   K +G  K I      +  +Q + +K
Sbjct: 94  CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
              +H D F C+NC + +   +   KGE  YC+ CH+      C  C + I    +    
Sbjct: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNAMG 209

Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           + WH + FVC  C K   G R    +   YC   Y       C  C   I G
Sbjct: 210 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG 261



 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 8/198 (4%)

Query: 39  TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
           TC  C+       K V+     +H+ CF CA+C        F   + +  C        +
Sbjct: 9   TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68

Query: 99  PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
           P C  C + I+   + ++     WH +CF C  C++V+    F        C  CH  + 
Sbjct: 69  PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126

Query: 159 AKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
           A+      C KC+  I    + +++ P+H D F C  C K+L       ++ + YC+ C+
Sbjct: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCH 185

Query: 214 KNFVAKKCAGCKNPITGK 231
                  C  C+ PI G+
Sbjct: 186 DKMGVPICGACRRPIEGR 203



 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 62/221 (28%), Positives = 95/221 (42%), Gaps = 13/221 (5%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57
           E F C  C++ L    +V+  G H C  C ++  A       C +C   I  D + + +K
Sbjct: 93  ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150

Query: 58  NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
           N  +H   F CA C   L  +    K  ++ C  C  +   P C  C + I    + V  
Sbjct: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207

Query: 118 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY 176
            G  WH + F C+ C K  +G   +  KG   YC T +   F   C  CN+ I    ++ 
Sbjct: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGLA-YCETHYNQLFGDVCFHCNRVIEGDVVSA 266

Query: 177 QDQPWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNF 216
            ++ W  +CF C TC+ KL    +F   + +  C  CY+ F
Sbjct: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307



 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 8/132 (6%)

Query: 98  SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
           S  C+ C       ++ V   G ++H+ CF C+ C Q    G F+      YC    +  
Sbjct: 7   SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66

Query: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK--- 214
           FA  C +C + I    I   +  WH +CF C  C + LA   F     ++ C  C+    
Sbjct: 67  FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126

Query: 215 -----NFVAKKC 221
                 ++ +KC
Sbjct: 127 ARGLGKYICQKC 138


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  103 bits (257), Expect = 2e-22
 Identities = 66/232 (28%), Positives = 92/232 (39%), Gaps = 12/232 (5%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  P     + + +G   C   F    A  C  C + I    + +   N  WH  
Sbjct: 63  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
           CFRC  C   LA+  FV    + LC  C  RE   K KG  K I      V  +Q + ++
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 177

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
              +H D F C++C + +   +   KGE  YC+ CH+      C  C + I    +    
Sbjct: 178 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 236

Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           + WH + FVC  C K   G R    +   YC   Y       C  C + I G
Sbjct: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 288



 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 8/204 (3%)

Query: 33  DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
           D      C  C+       + V+     +H+ CF CA+C  P     F   + +  C   
Sbjct: 30  DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89

Query: 93  TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
                +P C  C + I+   + ++     WH  CF C  C   +    F        C  
Sbjct: 90  FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147

Query: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
           CH  + AK      C +C+  I    + ++   +H D F C  C K+L  +    ++ + 
Sbjct: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 206

Query: 208 YCVDCYKNFVAKKCAGCKNPITGK 231
           YC+ C+       C  C+ PI G+
Sbjct: 207 YCLPCHDKMGVPICGACRRPIEGR 230



 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 60/249 (24%), Positives = 98/249 (39%), Gaps = 21/249 (8%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYKNR 59
           F C  C   L    +V+  G H C  C ++  A       C  C   I  D + + +++ 
Sbjct: 122 FRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRSD 179

Query: 60  FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 119
            +H   F C  C   L  E    K  ++ C  C  +   P C  C + I    + V   G
Sbjct: 180 AYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNALG 236

Query: 120 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 179
             WH + F C+ C++       + K    YC T +   F   C  C+  I    ++  ++
Sbjct: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK 296

Query: 180 PWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVS 238
            W   CF C TC+ KL    +F   + +  C  CY+ F          P+  K+ + ++S
Sbjct: 297 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF----------PLELKKRLKKLS 346

Query: 239 HPVSKARKP 247
              S+  +P
Sbjct: 347 ELTSRKAQP 355


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  103 bits (257), Expect = 2e-22
 Identities = 66/232 (28%), Positives = 92/232 (39%), Gaps = 12/232 (5%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  P     + + +G   C   F    A  C  C + I    + +   N  WH  
Sbjct: 36  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 93

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
           CFRC  C   LA+  FV    + LC  C  RE   K KG  K I      V  +Q + ++
Sbjct: 94  CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 150

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
              +H D F C++C + +   +   KGE  YC+ CH+      C  C + I    +    
Sbjct: 151 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 209

Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           + WH + FVC  C K   G R    +   YC   Y       C  C + I G
Sbjct: 210 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 261



 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 8/204 (3%)

Query: 33  DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
           D      C  C+       + V+     +H+ CF CA+C  P     F   + +  C   
Sbjct: 3   DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 62

Query: 93  TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
                +P C  C + I+   + ++     WH  CF C  C   +    F        C  
Sbjct: 63  FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 120

Query: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
           CH  + AK      C +C+  I    + ++   +H D F C  C K+L  +    ++ + 
Sbjct: 121 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 179

Query: 208 YCVDCYKNFVAKKCAGCKNPITGK 231
           YC+ C+       C  C+ PI G+
Sbjct: 180 YCLPCHDKMGVPICGACRRPIEGR 203



 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 60/249 (24%), Positives = 98/249 (39%), Gaps = 21/249 (8%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYKNR 59
           F C  C   L    +V+  G H C  C ++  A       C  C   I  D + + +++ 
Sbjct: 95  FRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRSD 152

Query: 60  FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 119
            +H   F C  C   L  E    K  ++ C  C  +   P C  C + I    + V   G
Sbjct: 153 AYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNALG 209

Query: 120 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 179
             WH + F C+ C++       + K    YC T +   F   C  C+  I    ++  ++
Sbjct: 210 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK 269

Query: 180 PWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVS 238
            W   CF C TC+ KL    +F   + +  C  CY+ F          P+  K+ + ++S
Sbjct: 270 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF----------PLELKKRLKKLS 319

Query: 239 HPVSKARKP 247
              S+  +P
Sbjct: 320 ELTSRKAQP 328


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  103 bits (257), Expect = 2e-22
 Identities = 66/232 (28%), Positives = 92/232 (39%), Gaps = 12/232 (5%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  P     + + +G   C   F    A  C  C + I    + +   N  WH  
Sbjct: 41  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 98

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
           CFRC  C   LA+  FV    + LC  C  RE   K KG  K I      V  +Q + ++
Sbjct: 99  CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 155

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
              +H D F C++C + +   +   KGE  YC+ CH+      C  C + I    +    
Sbjct: 156 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 214

Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           + WH + FVC  C K   G R    +   YC   Y       C  C + I G
Sbjct: 215 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 266



 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 8/204 (3%)

Query: 33  DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
           D      C  C+       + V+     +H+ CF CA+C  P     F   + +  C   
Sbjct: 8   DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 67

Query: 93  TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
                +P C  C + I+   + ++     WH  CF C  C   +    F        C  
Sbjct: 68  FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 125

Query: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
           CH  + AK      C +C+  I    + ++   +H D F C  C K+L  +    ++ + 
Sbjct: 126 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 184

Query: 208 YCVDCYKNFVAKKCAGCKNPITGK 231
           YC+ C+       C  C+ PI G+
Sbjct: 185 YCLPCHDKMGVPICGACRRPIEGR 208



 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 60/249 (24%), Positives = 98/249 (39%), Gaps = 21/249 (8%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYKNR 59
           F C  C   L    +V+  G H C  C ++  A       C  C   I  D + + +++ 
Sbjct: 100 FRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRSD 157

Query: 60  FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 119
            +H   F C  C   L  E    K  ++ C  C  +   P C  C + I    + V   G
Sbjct: 158 AYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNALG 214

Query: 120 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 179
             WH + F C+ C++       + K    YC T +   F   C  C+  I    ++  ++
Sbjct: 215 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK 274

Query: 180 PWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVS 238
            W   CF C TC+ KL    +F   + +  C  CY+ F          P+  K+ + ++S
Sbjct: 275 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF----------PLELKKRLKKLS 324

Query: 239 HPVSKARKP 247
              S+  +P
Sbjct: 325 ELTSRKAQP 333


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  103 bits (257), Expect = 2e-22
 Identities = 66/232 (28%), Positives = 92/232 (39%), Gaps = 12/232 (5%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C  P     + + +G   C   F    A  C  C + I    + +   N  WH  
Sbjct: 65  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 122

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
           CFRC  C   LA+  FV    + LC  C  RE   K KG  K I      V  +Q + ++
Sbjct: 123 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 179

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
              +H D F C++C + +   +   KGE  YC+ CH+      C  C + I    +    
Sbjct: 180 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 238

Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
           + WH + FVC  C K   G R    +   YC   Y       C  C + I G
Sbjct: 239 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 290



 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 8/204 (3%)

Query: 33  DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
           D      C  C+       + V+     +H+ CF CA+C  P     F   + +  C   
Sbjct: 32  DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 91

Query: 93  TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
                +P C  C + I+   + ++     WH  CF C  C   +    F        C  
Sbjct: 92  FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 149

Query: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
           CH  + AK      C +C+  I    + ++   +H D F C  C K+L  +    ++ + 
Sbjct: 150 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 208

Query: 208 YCVDCYKNFVAKKCAGCKNPITGK 231
           YC+ C+       C  C+ PI G+
Sbjct: 209 YCLPCHDKMGVPICGACRRPIEGR 232



 Score = 85.5 bits (210), Expect = 6e-17
 Identities = 60/249 (24%), Positives = 98/249 (39%), Gaps = 21/249 (8%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYKNR 59
           F C  C   L    +V+  G H C  C ++  A       C  C   I  D + + +++ 
Sbjct: 124 FRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRSD 181

Query: 60  FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 119
            +H   F C  C   L  E    K  ++ C  C  +   P C  C + I    + V   G
Sbjct: 182 AYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNALG 238

Query: 120 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 179
             WH + F C+ C++       + K    YC T +   F   C  C+  I    ++  ++
Sbjct: 239 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK 298

Query: 180 PWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVS 238
            W   CF C TC+ KL    +F   + +  C  CY+ F          P+  K+ + ++S
Sbjct: 299 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF----------PLELKKRLKKLS 348

Query: 239 HPVSKARKP 247
              S+  +P
Sbjct: 349 ELTSRKAQP 357


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  101 bits (252), Expect = 8e-22
 Identities = 57/211 (27%), Positives = 85/211 (40%), Gaps = 4/211 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C   L G  + +KDG   C +C+ +  +  C  C +PI    K V      WH
Sbjct: 250 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTALGTHWH 307

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F C  C  P  +E F  ++ +  C +   +  +P+C+GC   I+  D  +     +W
Sbjct: 308 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 365

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
           H DCF C  C      GSFF       C      +    C  C   +T   ++   + +H
Sbjct: 366 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 425

Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
            D F C  C + L    F     + YC  C+
Sbjct: 426 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 456



 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 62/203 (30%), Positives = 80/203 (39%), Gaps = 6/203 (2%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C KPI    + V    R WH   F C  C   L   +F  KD    C +C     SP
Sbjct: 228 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C + I    + V   GT WH + F C +C +  G   F  +    YC       FA
Sbjct: 286 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343

Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
             C  C   I    I+     WH DCFVC  C    +G  F   E +  C + +      
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403

Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
            CA C  P+TG+    + R  HP
Sbjct: 404 LCATCGLPVTGRCVSALGRRFHP 426


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  101 bits (252), Expect = 8e-22
 Identities = 57/211 (27%), Positives = 85/211 (40%), Gaps = 4/211 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E F C  C   L G  + +KDG   C +C+ +  +  C  C +PI    K V      WH
Sbjct: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTALGTHWH 290

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
              F C  C  P  +E F  ++ +  C +   +  +P+C+GC   I+  D  +     +W
Sbjct: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 348

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
           H DCF C  C      GSFF       C      +    C  C   +T   ++   + +H
Sbjct: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408

Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
            D F C  C + L    F     + YC  C+
Sbjct: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439



 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 62/203 (30%), Positives = 80/203 (39%), Gaps = 6/203 (2%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C  C KPI    + V    R WH   F C  C   L   +F  KD    C +C     SP
Sbjct: 211 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
           +C  C + I    + V   GT WH + F C +C +  G   F  +    YC       FA
Sbjct: 269 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326

Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
             C  C   I    I+     WH DCFVC  C    +G  F   E +  C + +      
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386

Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
            CA C  P+TG+    + R  HP
Sbjct: 387 LCATCGLPVTGRCVSALGRRFHP 409


>gi|38524620 prickle-like 2 [Homo sapiens]
          Length = 844

 Score =  101 bits (251), Expect = 1e-21
 Identities = 68/249 (27%), Positives = 105/249 (42%), Gaps = 14/249 (5%)

Query: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
           WH  CF C  C   L +  +  +D KI C +       P+C  C + I A D+  E +G 
Sbjct: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213

Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
            WH   F C  C+ V+G   +  K    YC  C E+ +A++C  C +   I  G +TY  
Sbjct: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273

Query: 179 QPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSR 236
           Q WHA   CF C  C K L G+ F   + Q +C        ++ C+  ++P     + S 
Sbjct: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC--------SRACSAGEDPNGSDSSDSA 325

Query: 237 VSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLA-APRG 295
             +  +K  +     GK    T  P  N   +         + V  L  +   L+ + + 
Sbjct: 326 FQNARAKESRRSAKIGKNKGKTEEPMLNQHSQLQVSSNRLSADVDPLSLQMDMLSLSSQT 385

Query: 296 PGLVKAPVW 304
           P L + P+W
Sbjct: 386 PSLNRDPIW 394



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 62
           F C  C   L G++Y+ K+G   C  CF+   A  C  C + IG D  ++ Y  + WH  
Sbjct: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
           +TCF CA C   L    F+ K  +I C++ C+  ED
Sbjct: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 5/133 (3%)

Query: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
           C+ C   I  GD  V       G  WH  CF C+ C +++    +F +    YC   H  
Sbjct: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189

Query: 157 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
                C  C++ I +   T  + + WH   F C  C   L GQR+   E + YC  C+++
Sbjct: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249

Query: 216 FVAKKCAGCKNPI 228
             A+ C  C   I
Sbjct: 250 LYAEYCDTCAQHI 262



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C + L    Y  +DG   C +   +     C  C + I AD      + R WH  
Sbjct: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
            F C +C   L  + ++ K+ +  C  C     +  C  C + I      + Y G  WH 
Sbjct: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278

Query: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
            + CF C++CK+ +    F PK    +C
Sbjct: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 58
           F C +C+  L G+ ++ K G          FC+  C     P G+DS +  ++N
Sbjct: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E+F C YC+  L    +V++  +  C +C+++F A  C +C   I  +   +H   + WH
Sbjct: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
            TCF CA C  P  N  F  +D +  C K      S KC GC   + AGD+ +E  G  W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
           H  CF C+ C   +    F+ K +   C
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608



 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 118
           R WH   F CA C   LA+  FV + N + C +C  +  +P C  C   I+   + +   
Sbjct: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 515

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 176
              WH  CF C+ CK+  G   F  +  + YC   +   F+  C  C+  + +G   I  
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575

Query: 177 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
               WH  CF+C  C   L GQ F + +D+  C
Sbjct: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 41/122 (33%), Positives = 55/122 (45%), Gaps = 1/122 (0%)

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
           G  WH + FTC+ CK  +    F  +  + YC  C+E  FA  C KCN  I    +    
Sbjct: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516

Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPI-TGKRTVSRV 237
           Q WH  CFVC  C K      F   + + YC   Y N  + KC GC  P+  G + +  +
Sbjct: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEAL 576

Query: 238 SH 239
            H
Sbjct: 577 GH 578



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 28/87 (32%), Positives = 39/87 (44%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+ P     +  +DG   C K +    +  C  C  P+ A  K +      WHDT
Sbjct: 524 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 583

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNK 91
           CF CA C   L  + F +K ++ LC K
Sbjct: 584 CFICAVCHVNLEGQPFYSKKDRPLCKK 610



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 23/70 (32%), Positives = 30/70 (42%)

Query: 162 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 221
           C  CN  I    +    + WH + F C  C   LA   F   ++  YC  CY+ F A  C
Sbjct: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500

Query: 222 AGCKNPITGK 231
           A C   I G+
Sbjct: 501 AKCNTKIMGE 510


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 99.0 bits (245), Expect = 5e-21
 Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)

Query: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
           E+F C YC+  L    +V++  +  C +C+++F A  C +C   I  +   +H   + WH
Sbjct: 573 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 630

Query: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
            TCF CA C  P  N  F  +D +  C K      S KC GC   + AGD+ +E  G  W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690

Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
           H  CF C+ C   +    F+ K +   C
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC 718



 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)

Query: 59  RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 118
           R WH   F CA C   LA+  FV + N + C +C  +  +P C  C   I+   + +   
Sbjct: 568 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 625

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 176
              WH  CF C+ CK+  G   F  +  + YC   +   F+  C  C+  + +G   I  
Sbjct: 626 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 685

Query: 177 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
               WH  CF+C  C   L GQ F + +D+  C
Sbjct: 686 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 41/122 (33%), Positives = 55/122 (45%), Gaps = 1/122 (0%)

Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
           G  WH + FTC+ CK  +    F  +  + YC  C+E  FA  C KCN  I    +    
Sbjct: 567 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 626

Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPI-TGKRTVSRV 237
           Q WH  CFVC  C K      F   + + YC   Y N  + KC GC  P+  G + +  +
Sbjct: 627 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEAL 686

Query: 238 SH 239
            H
Sbjct: 687 GH 688



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 28/87 (32%), Positives = 39/87 (44%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C+ P     +  +DG   C K +    +  C  C  P+ A  K +      WHDT
Sbjct: 634 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 693

Query: 65  CFRCAKCLHPLANETFVAKDNKILCNK 91
           CF CA C   L  + F +K ++ LC K
Sbjct: 694 CFICAVCHVNLEGQPFYSKKDRPLCKK 720



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 23/70 (32%), Positives = 30/70 (42%)

Query: 162 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 221
           C  CN  I    +    + WH + F C  C   LA   F   ++  YC  CY+ F A  C
Sbjct: 551 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 610

Query: 222 AGCKNPITGK 231
           A C   I G+
Sbjct: 611 AKCNTKIMGE 620


>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
          Length = 746

 Score = 95.9 bits (237), Expect = 4e-20
 Identities = 60/202 (29%), Positives = 87/202 (43%), Gaps = 15/202 (7%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C +C +P   +   V  K+  +H  CF C  C   LA   F  K+ + LC     R    
Sbjct: 39  CHKCGEPCKGEVLRVQTKH--FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGT 96

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC----- 153
           +C GC + +    + V   G  +H +CF C+ CK+    G      G D  C  C     
Sbjct: 97  RCHGCGEFVEG--EVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154

Query: 154 ---HETKFAKHCVKCNKAITSG-GITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
               ET F+ +C  C + I +G  +   D+ WH  CF C +C K L G+ + + +   YC
Sbjct: 155 SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYC 213

Query: 210 VDCYKNFVAKKCAGCKNPITGK 231
              Y+     KC  C   ITGK
Sbjct: 214 EKDYQGLFGVKCEACHQFITGK 235



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 22/214 (10%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C   L    +  K+G + C   + +     C  C + +  + + V    + +H  
Sbjct: 63  FTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFV--EGEVVTALGKTYHPN 120

Query: 65  CFRCAKCLHPLA---NETFVAKDNKILCNKCTT-REDSPK-------CKGCFKAIVAGDQ 113
           CF C  C  P       TF  +D   LC  C      SPK       C GC + I  G Q
Sbjct: 121 CFACTICKRPFPPGDRVTFNGRD--CLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNG-Q 177

Query: 114 NVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG 173
            +      WH  CF C +C +V+ TG +  K    YC   ++  F   C  C++ IT   
Sbjct: 178 ALLALDKQWHLGCFKCKSCGKVL-TGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKV 236

Query: 174 ITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
           +   D+ +H  C  C  C+     Q FT  E+ Y
Sbjct: 237 LEAGDKHYHPSCARCSRCN-----QMFTEGEEMY 265



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 23/151 (15%)

Query: 87  ILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE 146
           I C+KC        CKG         + +  +   +H  CFTC  C   +  G FF K  
Sbjct: 37  IHCHKC-----GEPCKG---------EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNG 82

Query: 147 DFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKL-AGQRFTAVED 205
           ++ C   ++  +   C  C + +    +T   + +H +CF C  C +    G R T    
Sbjct: 83  EYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGR 142

Query: 206 QYYCVDC--------YKNFVAKKCAGCKNPI 228
              C  C         +   +  CAGC   I
Sbjct: 143 DCLCQLCAQPMSSSPKETTFSSNCAGCGRDI 173



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 2/82 (2%)

Query: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
           HC KC +      +  Q + +H  CF C  C   LA   F     +Y C   Y+     +
Sbjct: 38  HCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 97

Query: 221 CAGCKNPITGK--RTVSRVSHP 240
           C GC   + G+    + +  HP
Sbjct: 98  CHGCGEFVEGEVVTALGKTYHP 119



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 39/180 (21%), Positives = 63/180 (35%), Gaps = 37/180 (20%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHC-CLKCFDKFCAN--------TCVECRKPIGADSKEVH 55
           F C  C+ P      V  +G  C C  C     ++         C  C + I  + + + 
Sbjct: 122 FACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDI-KNGQALL 180

Query: 56  YKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCF-----KAIVA 110
             ++ WH  CF+C  C   L  E +++KD    C K        KC+ C      K + A
Sbjct: 181 ALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEA 239

Query: 111 GDQNVEYK---------------------GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 149
           GD++                          TVWH DC   +  ++ +   +      DF+
Sbjct: 240 GDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFF 299


>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
          Length = 718

 Score = 95.9 bits (237), Expect = 4e-20
 Identities = 60/202 (29%), Positives = 87/202 (43%), Gaps = 15/202 (7%)

Query: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
           C +C +P   +   V  K+  +H  CF C  C   LA   F  K+ + LC     R    
Sbjct: 39  CHKCGEPCKGEVLRVQTKH--FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGT 96

Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC----- 153
           +C GC + +    + V   G  +H +CF C+ CK+    G      G D  C  C     
Sbjct: 97  RCHGCGEFVEG--EVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154

Query: 154 ---HETKFAKHCVKCNKAITSG-GITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
               ET F+ +C  C + I +G  +   D+ WH  CF C +C K L G+ + + +   YC
Sbjct: 155 SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYC 213

Query: 210 VDCYKNFVAKKCAGCKNPITGK 231
              Y+     KC  C   ITGK
Sbjct: 214 EKDYQGLFGVKCEACHQFITGK 235



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 22/214 (10%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
           F C  C   L    +  K+G + C   + +     C  C + +  + + V    + +H  
Sbjct: 63  FTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFV--EGEVVTALGKTYHPN 120

Query: 65  CFRCAKCLHPLA---NETFVAKDNKILCNKCTT-REDSPK-------CKGCFKAIVAGDQ 113
           CF C  C  P       TF  +D   LC  C      SPK       C GC + I  G Q
Sbjct: 121 CFACTICKRPFPPGDRVTFNGRD--CLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNG-Q 177

Query: 114 NVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG 173
            +      WH  CF C +C +V+ TG +  K    YC   ++  F   C  C++ IT   
Sbjct: 178 ALLALDKQWHLGCFKCKSCGKVL-TGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKV 236

Query: 174 ITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
           +   D+ +H  C  C  C+     Q FT  E+ Y
Sbjct: 237 LEAGDKHYHPSCARCSRCN-----QMFTEGEEMY 265



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 23/151 (15%)

Query: 87  ILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE 146
           I C+KC        CKG         + +  +   +H  CFTC  C   +  G FF K  
Sbjct: 37  IHCHKC-----GEPCKG---------EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNG 82

Query: 147 DFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKL-AGQRFTAVED 205
           ++ C   ++  +   C  C + +    +T   + +H +CF C  C +    G R T    
Sbjct: 83  EYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGR 142

Query: 206 QYYCVDC--------YKNFVAKKCAGCKNPI 228
              C  C         +   +  CAGC   I
Sbjct: 143 DCLCQLCAQPMSSSPKETTFSSNCAGCGRDI 173



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 2/82 (2%)

Query: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
           HC KC +      +  Q + +H  CF C  C   LA   F     +Y C   Y+     +
Sbjct: 38  HCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 97

Query: 221 CAGCKNPITGK--RTVSRVSHP 240
           C GC   + G+    + +  HP
Sbjct: 98  CHGCGEFVEGEVVTALGKTYHP 119



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 37/157 (23%), Positives = 55/157 (35%), Gaps = 37/157 (23%)

Query: 5   FDCHYCRDPLQGKKYVQKDGHHC-CLKCFDKFCAN--------TCVECRKPIGADSKEVH 55
           F C  C+ P      V  +G  C C  C     ++         C  C + I  + + + 
Sbjct: 122 FACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDI-KNGQALL 180

Query: 56  YKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCF-----KAIVA 110
             ++ WH  CF+C  C   L  E +++KD    C K        KC+ C      K + A
Sbjct: 181 ALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEA 239

Query: 111 GDQNVEYK---------------------GTVWHKDC 126
           GD++                          TVWH DC
Sbjct: 240 GDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDC 276


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.481 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,838,767
Number of Sequences: 37866
Number of extensions: 773015
Number of successful extensions: 6842
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 594
Number of HSP's that attempted gapping in prelim test: 2945
Number of HSP's gapped (non-prelim): 2367
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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