Guide to the Human Genome
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Search of human proteins with 22749357

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749357 chromosome 2 open reading frame 51 [Homo sapiens]
         (180 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749357 chromosome 2 open reading frame 51 [Homo sapiens]         392   e-110
gi|239752961 PREDICTED: hypothetical protein [Homo sapiens]            35   0.035
gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog ...    32   0.23 
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    30   1.5  
gi|190343021 Sec24-related protein D [Homo sapiens]                    29   2.5  
gi|30911103 pygopus homolog 1 [Homo sapiens]                           29   2.5  
gi|150418005 protein tyrosine phosphatase, non-receptor type 21 ...    28   3.3  
gi|110825982 hect domain and RLD 5 [Homo sapiens]                      28   3.3  
gi|4507483 thrombomodulin precursor [Homo sapiens]                     28   4.3  
gi|61563742 hect domain and RLD 6 [Homo sapiens]                       28   4.3  
gi|188497705 BRCA1 associated protein [Homo sapiens]                   28   5.6  
gi|194097341 period 1 [Homo sapiens]                                   27   7.3  
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...    27   7.3  
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...    27   7.3  
gi|157427675 ADAM metallopeptidase with thrombospondin type 1 mo...    27   7.3  
gi|19923399 Ras-GTPase activating protein SH3 domain-binding pro...    27   7.3  
gi|45359849 Ras-GTPase activating protein SH3 domain-binding pro...    27   7.3  
gi|71274152 hypothetical protein LOC388939 [Homo sapiens]              27   9.5  
gi|78191787 early estrogen-induced gene 1 protein isoform a [Hom...    27   9.5  
gi|42558264 early estrogen-induced gene 1 protein isoform b [Hom...    27   9.5  

>gi|22749357 chromosome 2 open reading frame 51 [Homo sapiens]
          Length = 180

 Score =  392 bits (1007), Expect = e-110
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MAGVKYPGQDPVDLDIYQSSHMVDYQPYRKHKYSRVTPQEQAKLDAQLRDKEFYRPIPNP 60
           MAGVKYPGQDPVDLDIYQSSHMVDYQPYRKHKYSRVTPQEQAKLDAQLRDKEFYRPIPNP
Sbjct: 1   MAGVKYPGQDPVDLDIYQSSHMVDYQPYRKHKYSRVTPQEQAKLDAQLRDKEFYRPIPNP 60

Query: 61  NPKLTDGYPAFKRPHMTAKDLGLPGFFPSQEHEATREDERKFTSTCHFTYPASHDLHLAQ 120
           NPKLTDGYPAFKRPHMTAKDLGLPGFFPSQEHEATREDERKFTSTCHFTYPASHDLHLAQ
Sbjct: 61  NPKLTDGYPAFKRPHMTAKDLGLPGFFPSQEHEATREDERKFTSTCHFTYPASHDLHLAQ 120

Query: 121 GDPNQVLQSADFPCLVDPKHQPAAEMAKGYLLLPGCPCLHCHIVKVPILNRWGPLMPFYQ 180
           GDPNQVLQSADFPCLVDPKHQPAAEMAKGYLLLPGCPCLHCHIVKVPILNRWGPLMPFYQ
Sbjct: 121 GDPNQVLQSADFPCLVDPKHQPAAEMAKGYLLLPGCPCLHCHIVKVPILNRWGPLMPFYQ 180


>gi|239752961 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 366

 Score = 35.0 bits (79), Expect = 0.035
 Identities = 15/39 (38%), Positives = 22/39 (56%)

Query: 122 DPNQVLQSADFPCLVDPKHQPAAEMAKGYLLLPGCPCLH 160
           +P   L +   P  + P H+  +E A+ +LL PG PCLH
Sbjct: 73  EPAPALNAKTTPKFLGPPHKTKSECARPHLLGPGSPCLH 111


>gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog
           (Arabidopsis)(non-functional)-like [Homo sapiens]
          Length = 568

 Score = 32.3 bits (72), Expect = 0.23
 Identities = 24/103 (23%), Positives = 48/103 (46%), Gaps = 3/103 (2%)

Query: 38  PQEQAKLDAQLRDKEFYRPIPNPNPKLTDGYPAFKRPHMTAKDLGLPGFFPS--QEHEAT 95
           P E ++ D +   +      P+P P+L+D   AF    ++ + + +  F+ S  Q++ A 
Sbjct: 97  PSEDSRGDVRYGQRAQLSGQPDPVPQLSDCEAAFVNRDLSIRGIDISVFYQSSFQDYNAY 156

Query: 96  REDE-RKFTSTCHFTYPASHDLHLAQGDPNQVLQSADFPCLVD 137
           ++D+  K  +T  F    + +  L      + LQ +D  C+ D
Sbjct: 157 QKDKYHKDKNTLGFINLGTSENKLCMDLMTERLQESDMNCIED 199


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 29.6 bits (65), Expect = 1.5
 Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 1/62 (1%)

Query: 80  DLGLPGFFPSQEHEATREDERKFTSTCHFTYPASHDLHLAQGDPNQVLQSADFPCLVDPK 139
           D G     PS  H +T +++ K T   H+       +HL    PN+++ +     L  P 
Sbjct: 44  DQGFASLQPSLHHPSTNQNQTKLTHFDHYNQYEQQKMHL-MDQPNRMMSNTPGNGLASPH 102

Query: 140 HQ 141
            Q
Sbjct: 103 SQ 104


>gi|190343021 Sec24-related protein D [Homo sapiens]
          Length = 1032

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 16/38 (42%), Positives = 17/38 (44%), Gaps = 3/38 (7%)

Query: 54  YRPIPNPNPKLTDGYP---AFKRPHMTAKDLGLPGFFP 88
           Y+P P P   L  GYP   A   P M    L  PG FP
Sbjct: 206 YQPPPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFP 243


>gi|30911103 pygopus homolog 1 [Homo sapiens]
          Length = 419

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 10/18 (55%), Positives = 13/18 (72%)

Query: 54 YRPIPNPNPKLTDGYPAF 71
          Y+P+P+ NP L  GYP F
Sbjct: 81 YKPLPSSNPYLGPGYPGF 98


>gi|150418005 protein tyrosine phosphatase, non-receptor type 21
           [Homo sapiens]
          Length = 1174

 Score = 28.5 bits (62), Expect = 3.3
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 6/59 (10%)

Query: 41  QAKLDAQLRDKEFY-----RPIPNPNPKLTDGYPAFKRPHMTAKDLGLPGFFPSQEHEA 94
           Q  L+ ++R+   Y       + NP P L    P    P +T  D+  P + PS  H A
Sbjct: 382 QIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPS-PMSSNPSITGSDVMRPDYLPSHRHSA 439


>gi|110825982 hect domain and RLD 5 [Homo sapiens]
          Length = 1024

 Score = 28.5 bits (62), Expect = 3.3
 Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 8/42 (19%)

Query: 138 PKHQPAAEMAKGYLLLPGCPCLHCHIVKVPILNRWGPL-MPF 178
           P H P  E  + + LLP CP +H       I N W  L +PF
Sbjct: 478 PFHSPPQEALEIFFLLPECPMMH-------ISNNWESLVVPF 512


>gi|4507483 thrombomodulin precursor [Homo sapiens]
          Length = 575

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 5/76 (6%)

Query: 84  PGFFPSQEHEATREDERKFTSTCHFTY-PASHDLHLAQGDPNQVLQSADFPCLVDPKHQP 142
           P F  + E++    ++  +   C   + P  H+ H  Q   NQ    AD     DP  Q 
Sbjct: 368 PCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPAD----CDPNTQA 423

Query: 143 AAEMAKGYLLLPGCPC 158
           + E  +GY+L  G  C
Sbjct: 424 SCECPEGYILDDGFIC 439


>gi|61563742 hect domain and RLD 6 [Homo sapiens]
          Length = 1022

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 11/23 (47%), Positives = 13/23 (56%)

Query: 138 PKHQPAAEMAKGYLLLPGCPCLH 160
           P H P  E    +LLLP CP +H
Sbjct: 470 PCHSPHQEALSVFLLLPECPVMH 492


>gi|188497705 BRCA1 associated protein [Homo sapiens]
          Length = 592

 Score = 27.7 bits (60), Expect = 5.6
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 7/103 (6%)

Query: 30  KHKYSRVTPQEQAKLDAQLRDKEFYRPIPN-PNPKLTDGYPAFKRPHMTAKDLGLPGFFP 88
           + K S  +P  Q   D     KE     P+ P+ +L D    F          G+   + 
Sbjct: 90  ERKSSEASPTAQRSKD---HSKECINAAPDSPSKQLPDQISFFSGNPSVEIVHGIMHLYK 146

Query: 89  SQEHEATREDERKFTSTCHFTYPA---SHDLHLAQGDPNQVLQ 128
           + +  + +ED R+    C  T PA   SHDL       N+V++
Sbjct: 147 TNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKFVAPFNEVIE 189


>gi|194097341 period 1 [Homo sapiens]
          Length = 1290

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 17/59 (28%), Positives = 27/59 (45%)

Query: 16  IYQSSHMVDYQPYRKHKYSRVTPQEQAKLDAQLRDKEFYRPIPNPNPKLTDGYPAFKRP 74
           I +  H+V +Q  +    SR  PQ + +L A    K    P  +P+P+L  G    + P
Sbjct: 549 ICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAGSAPVQAP 607


>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
            sapiens]
          Length = 1632

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 18/69 (26%), Positives = 34/69 (49%), Gaps = 16/69 (23%)

Query: 4    VKYPGQDPVDLDIY-----------QSSHMVDYQPYRKHKYSRVTPQEQA-----KLDAQ 47
            VK P ++PVD D+Y           + S++   +PYR  +   +   +++     + D +
Sbjct: 972  VKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIK 1031

Query: 48   LRDKEFYRP 56
            +R  +FYRP
Sbjct: 1032 IRVNKFYRP 1040


>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
            sapiens]
          Length = 1616

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 18/69 (26%), Positives = 34/69 (49%), Gaps = 16/69 (23%)

Query: 4    VKYPGQDPVDLDIY-----------QSSHMVDYQPYRKHKYSRVTPQEQA-----KLDAQ 47
            VK P ++PVD D+Y           + S++   +PYR  +   +   +++     + D +
Sbjct: 956  VKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKKSNGRPNETDIK 1015

Query: 48   LRDKEFYRP 56
            +R  +FYRP
Sbjct: 1016 IRVNKFYRP 1024


>gi|157427675 ADAM metallopeptidase with thrombospondin type 1
           motif, 4 preproprotein [Homo sapiens]
          Length = 837

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 3/38 (7%)

Query: 32  KYSRVTPQEQAKLDAQLRDKEFYRPIPNPNPKLTDGYP 69
           +Y+ V PQ+Q KL  Q +   +Y  +    P++ DG P
Sbjct: 609 RYTGVAPQDQCKLTCQAQALGYYYVL---EPRVVDGTP 643


>gi|19923399 Ras-GTPase activating protein SH3 domain-binding
           protein 2 isoform a [Homo sapiens]
          Length = 482

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 18/76 (23%), Positives = 35/76 (46%)

Query: 6   YPGQDPVDLDIYQSSHMVDYQPYRKHKYSRVTPQEQAKLDAQLRDKEFYRPIPNPNPKLT 65
           +P  + ++  + +SSH  + +P  + K   + PQ + K   +L +K    P   P     
Sbjct: 179 HPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTTPPPAEPVSLPQ 238

Query: 66  DGYPAFKRPHMTAKDL 81
           +   AF    +T+K+L
Sbjct: 239 EPPKAFSWASVTSKNL 254


>gi|45359849 Ras-GTPase activating protein SH3 domain-binding
           protein 2 isoform a [Homo sapiens]
          Length = 482

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 18/76 (23%), Positives = 35/76 (46%)

Query: 6   YPGQDPVDLDIYQSSHMVDYQPYRKHKYSRVTPQEQAKLDAQLRDKEFYRPIPNPNPKLT 65
           +P  + ++  + +SSH  + +P  + K   + PQ + K   +L +K    P   P     
Sbjct: 179 HPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTTPPPAEPVSLPQ 238

Query: 66  DGYPAFKRPHMTAKDL 81
           +   AF    +T+K+L
Sbjct: 239 EPPKAFSWASVTSKNL 254


>gi|71274152 hypothetical protein LOC388939 [Homo sapiens]
          Length = 1288

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 6/43 (13%)

Query: 57   IPNPNPKLTDGYPAFKRPHMTAKDLGLPGFFPSQEHEATREDE 99
            +P+P  +  +  P F  P  +      P   PSQEH+ TR+ E
Sbjct: 1070 VPSPPTQHPEASPPFSIPSPS------PPMSPSQEHKETRDSE 1106


>gi|78191787 early estrogen-induced gene 1 protein isoform a [Homo
           sapiens]
          Length = 384

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 11/22 (50%), Positives = 13/22 (59%)

Query: 64  LTDGYPAFKRPHMTAKDLGLPG 85
           L  G P FK P  TAK + +PG
Sbjct: 145 LLSGDPCFKTPPSTAKSISIPG 166


>gi|42558264 early estrogen-induced gene 1 protein isoform b [Homo
          sapiens]
          Length = 242

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 11/22 (50%), Positives = 13/22 (59%)

Query: 64 LTDGYPAFKRPHMTAKDLGLPG 85
          L  G P FK P  TAK + +PG
Sbjct: 3  LLSGDPCFKTPPSTAKSISIPG 24


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,519,449
Number of Sequences: 37866
Number of extensions: 423106
Number of successful extensions: 887
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 875
Number of HSP's gapped (non-prelim): 23
length of query: 180
length of database: 18,247,518
effective HSP length: 96
effective length of query: 84
effective length of database: 14,612,382
effective search space: 1227440088
effective search space used: 1227440088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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