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Search of human proteins with 22748781
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22748781 tumor necrosis factor, alpha-induced protein 8-like
1 [Homo sapiens]
(186 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22748781 tumor necrosis factor, alpha-induced protein 8-like ... 365 e-102
gi|117676370 tumor necrosis factor, alpha-induced protein 8 isof... 231 2e-61
gi|117676365 tumor necrosis factor, alpha-induced protein 8 isof... 231 2e-61
gi|59709436 tumor necrosis factor, alpha-induced protein 8-like ... 212 2e-55
gi|157389001 tumor necrosis factor, alpha-induced protein 8-like... 206 1e-53
gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens] 29 2.0
gi|9507165 syntrophin, gamma 2 [Homo sapiens] 29 2.7
gi|62414289 vimentin [Homo sapiens] 28 3.5
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 28 4.6
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 28 4.6
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 28 4.6
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 28 4.6
gi|158321897 NACHT, LRR and PYD containing protein 5 [Homo sapiens] 28 4.6
gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens] 28 4.6
gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens] 28 4.6
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 27 7.8
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] 27 7.8
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 27 7.8
gi|5032285 dystrophin Dp427l isoform [Homo sapiens] 27 7.8
gi|5032283 dystrophin Dp427m isoform [Homo sapiens] 27 7.8
>gi|22748781 tumor necrosis factor, alpha-induced protein 8-like 1
[Homo sapiens]
Length = 186
Score = 365 bits (938), Expect = e-102
Identities = 186/186 (100%), Positives = 186/186 (100%)
Query: 1 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML 60
MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML
Sbjct: 1 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML 60
Query: 61 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGL 120
KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGL
Sbjct: 61 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGL 120
Query: 121 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM 180
LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM
Sbjct: 121 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM 180
Query: 181 LDEGSL 186
LDEGSL
Sbjct: 181 LDEGSL 186
>gi|117676370 tumor necrosis factor, alpha-induced protein 8 isoform
b [Homo sapiens]
Length = 188
Score = 231 bits (590), Expect = 2e-61
Identities = 105/185 (56%), Positives = 148/185 (80%)
Query: 2 DTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLK 61
D F++K+LA+QAQKK+L KM SK++ L+DDTSSEVLDELYR TRE+T+++KEA+K++K
Sbjct: 4 DVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIK 63
Query: 62 NLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGLL 121
NL+K +KL +L R +Q +ELAL+ +F+ + LAMT VSFHQVD+TFDR VL+ L
Sbjct: 64 NLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLN 123
Query: 122 ECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRML 181
ECR++LHQ + HLTAKSHGR+N+VF H +DC+FLAALY P ++ HL+++C+G+ +ML
Sbjct: 124 ECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKML 183
Query: 182 DEGSL 186
DE ++
Sbjct: 184 DEENI 188
>gi|117676365 tumor necrosis factor, alpha-induced protein 8 isoform
a [Homo sapiens]
Length = 198
Score = 231 bits (590), Expect = 2e-61
Identities = 105/185 (56%), Positives = 148/185 (80%)
Query: 2 DTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLK 61
D F++K+LA+QAQKK+L KM SK++ L+DDTSSEVLDELYR TRE+T+++KEA+K++K
Sbjct: 14 DVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIK 73
Query: 62 NLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGLL 121
NL+K +KL +L R +Q +ELAL+ +F+ + LAMT VSFHQVD+TFDR VL+ L
Sbjct: 74 NLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLN 133
Query: 122 ECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRML 181
ECR++LHQ + HLTAKSHGR+N+VF H +DC+FLAALY P ++ HL+++C+G+ +ML
Sbjct: 134 ECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKML 193
Query: 182 DEGSL 186
DE ++
Sbjct: 194 DEENI 198
>gi|59709436 tumor necrosis factor, alpha-induced protein 8-like 3
[Homo sapiens]
Length = 292
Score = 212 bits (539), Expect = 2e-55
Identities = 101/182 (55%), Positives = 140/182 (76%)
Query: 2 DTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLK 61
D FS+KSLALQAQKK+LSK+ASK V +L+DDTSSE+ DELY+ T+E T ++KEA K++K
Sbjct: 108 DVFSSKSLALQAQKKILSKIASKTVANMLIDDTSSEIFDELYKVTKEHTHNKKEAHKIMK 167
Query: 62 NLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGLL 121
+L+KVA+K+G+L R +Q EEL ++ +FR + AMT VSF++V++TFDR VL+ L
Sbjct: 168 DLIKVAIKIGILYRNNQFSQEELVIVEKFRKKLNQTAMTIVSFYEVEYTFDRNVLSNLLH 227
Query: 122 ECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRML 181
EC+DL+H+ V HLT ++HGRINHVF H AD +FL+ LY R +L+RICEG+ ++L
Sbjct: 228 ECKDLVHELVQRHLTPRTHGRINHVFNHFADVEFLSTLYSLDGDCRPNLKRICEGINKLL 287
Query: 182 DE 183
DE
Sbjct: 288 DE 289
>gi|157389001 tumor necrosis factor, alpha-induced protein 8-like 2
[Homo sapiens]
Length = 184
Score = 206 bits (523), Expect = 1e-53
Identities = 106/186 (56%), Positives = 139/186 (74%), Gaps = 2/186 (1%)
Query: 1 MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKML 60
M++FS+KSLALQA+KKLLSKMA ++V + +D+TSSEVLDELYR ++E+T SR +AQ+++
Sbjct: 1 MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVI 60
Query: 61 KNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGL 120
K+L+KVA+K+ +L R G ELAL RFR + R AMTA+SF +VDFTF+ VLA L
Sbjct: 61 KDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLL 120
Query: 121 LECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRM 180
ECRD+L + V HLT KSHGRI HVF H +D L ALYGP + HL +IC+GL ++
Sbjct: 121 TECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGP--DFTQHLGKICDGLRKL 178
Query: 181 LDEGSL 186
LDEG L
Sbjct: 179 LDEGKL 184
>gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]
Length = 984
Score = 29.3 bits (64), Expect = 2.0
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 10/73 (13%)
Query: 11 LQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLKNLVKVALKL 70
+Q +KK+ K+ S ++ D + + +E+ E RK ++ LKNL +KL
Sbjct: 875 VQYEKKIKRKLQS-----IIYDSNTRGIHNEISLGQCE--NKRKISEDKLKNL---RIKL 924
Query: 71 GLLLRGDQLGGEE 83
LLL+ QLGG E
Sbjct: 925 ALLLQKLQLGGPE 937
>gi|9507165 syntrophin, gamma 2 [Homo sapiens]
Length = 539
Score = 28.9 bits (63), Expect = 2.7
Identities = 28/136 (20%), Positives = 51/136 (37%), Gaps = 8/136 (5%)
Query: 17 LLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLKNLVKVALKLGLLLRG 76
LL +K +A+L D+ S D + T+E +K+ + + + + LR
Sbjct: 19 LLVPARTKTTIALLYDEESENAYDIRLKLTKEVLTIQKQDVVCVGGSHQGRNRRTVTLRR 78
Query: 77 DQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGLLECRDLLHQAVGPHLT 136
+GG L++ H + D T G+L D + Q G H+
Sbjct: 79 QPVGGLGLSIKGGSEHNVPVVISKIFEDQAADQT--------GMLFVGDAVLQVNGIHVE 130
Query: 137 AKSHGRINHVFGHLAD 152
+H + H+ + D
Sbjct: 131 NATHEEVVHLLRNAGD 146
>gi|62414289 vimentin [Homo sapiens]
Length = 466
Score = 28.5 bits (62), Expect = 3.5
Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 3/102 (2%)
Query: 25 AVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEEL 84
AV A DT + DE+ E R +E Q +L VK+AL + + L GEE
Sbjct: 352 AVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLN--VKMALDIEIATYRKLLEGEES 409
Query: 85 AL-LRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGLLECRD 125
+ L + L T + + T +R L + +E RD
Sbjct: 410 RISLPLPNFSSLNLRETNLDSLPLVDTHSKRTLLIKTVETRD 451
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 28.1 bits (61), Expect = 4.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 34 TSSEVLDELYRATREFTR---SRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRF 90
+SS LD RA + R R+E K+ +++ +L+ L + Q EL
Sbjct: 276 SSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTL 335
Query: 91 RHRARCLAMT--AVSFHQVDFTFDRRVLAVGL 120
RH CL+M A SF D + V +
Sbjct: 336 RHLFLCLSMLWFATSFAYYGLVMDLQGFGVSI 367
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 28.1 bits (61), Expect = 4.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 34 TSSEVLDELYRATREFTR---SRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRF 90
+SS LD RA + R R+E K+ +++ +L+ L + Q EL
Sbjct: 276 SSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTL 335
Query: 91 RHRARCLAMT--AVSFHQVDFTFDRRVLAVGL 120
RH CL+M A SF D + V +
Sbjct: 336 RHLFLCLSMLWFATSFAYYGLVMDLQGFGVSI 367
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 28.1 bits (61), Expect = 4.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 34 TSSEVLDELYRATREFTR---SRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRF 90
+SS LD RA + R R+E K+ +++ +L+ L + Q EL
Sbjct: 276 SSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTL 335
Query: 91 RHRARCLAMT--AVSFHQVDFTFDRRVLAVGL 120
RH CL+M A SF D + V +
Sbjct: 336 RHLFLCLSMLWFATSFAYYGLVMDLQGFGVSI 367
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 28.1 bits (61), Expect = 4.6
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%)
Query: 34 TSSEVLDELYRATREFTR---SRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRF 90
+SS LD RA + R R+E K+ +++ +L+ L + Q EL
Sbjct: 276 SSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTL 335
Query: 91 RHRARCLAMT--AVSFHQVDFTFDRRVLAVGL 120
RH CL+M A SF D + V +
Sbjct: 336 RHLFLCLSMLWFATSFAYYGLVMDLQGFGVSI 367
>gi|158321897 NACHT, LRR and PYD containing protein 5 [Homo sapiens]
Length = 1200
Score = 28.1 bits (61), Expect = 4.6
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 6/79 (7%)
Query: 82 EELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAVGLLECRDLLHQAVGPHLTAKSHG 141
EE +L+RF A S D D V +G E R L H + L SH
Sbjct: 523 EERVVLKRFCRMAVEGVWNRKSVFDGD---DLMVQGLGESELRALFHMNI---LLPDSHC 576
Query: 142 RINHVFGHLADCDFLAALY 160
+ F HL+ DF AALY
Sbjct: 577 EEYYTFFHLSLQDFCAALY 595
>gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens]
Length = 757
Score = 28.1 bits (61), Expect = 4.6
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 37 EVLDELYRATREFTRSRKEAQKMLKNLVKVALK 69
E D + +T+EF R KE K K VK LK
Sbjct: 491 ETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLK 523
>gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens]
Length = 757
Score = 28.1 bits (61), Expect = 4.6
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 37 EVLDELYRATREFTRSRKEAQKMLKNLVKVALK 69
E D + +T+EF R KE K K VK LK
Sbjct: 491 ETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLK 523
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 27.3 bits (59), Expect = 7.8
Identities = 15/52 (28%), Positives = 28/52 (53%)
Query: 7 KSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQK 58
K+++LQ + + ++A L D + DEL +A E R+++EAQ+
Sbjct: 1150 KTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMKRAKEEAQQ 1201
>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
Length = 3562
Score = 27.3 bits (59), Expect = 7.8
Identities = 15/52 (28%), Positives = 28/52 (53%)
Query: 7 KSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQK 58
K+++LQ + + ++A L D + DEL +A E R+++EAQ+
Sbjct: 1035 KTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMKRAKEEAQQ 1086
>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
Length = 3681
Score = 27.3 bits (59), Expect = 7.8
Identities = 15/52 (28%), Positives = 28/52 (53%)
Query: 7 KSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQK 58
K+++LQ + + ++A L D + DEL +A E R+++EAQ+
Sbjct: 1154 KTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMKRAKEEAQQ 1205
>gi|5032285 dystrophin Dp427l isoform [Homo sapiens]
Length = 3562
Score = 27.3 bits (59), Expect = 7.8
Identities = 15/52 (28%), Positives = 28/52 (53%)
Query: 7 KSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQK 58
K+++LQ + + ++A L D + DEL +A E R+++EAQ+
Sbjct: 1035 KTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMKRAKEEAQQ 1086
>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
Length = 3685
Score = 27.3 bits (59), Expect = 7.8
Identities = 15/52 (28%), Positives = 28/52 (53%)
Query: 7 KSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQK 58
K+++LQ + + ++A L D + DEL +A E R+++EAQ+
Sbjct: 1158 KTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMKRAKEEAQQ 1209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,145,271
Number of Sequences: 37866
Number of extensions: 237195
Number of successful extensions: 776
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 763
Number of HSP's gapped (non-prelim): 20
length of query: 186
length of database: 18,247,518
effective HSP length: 96
effective length of query: 90
effective length of database: 14,612,382
effective search space: 1315114380
effective search space used: 1315114380
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.