Guide to the Human Genome
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Search of human proteins with 22748707

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related)
[Homo sapiens]
         (248 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related) [Hom...   520   e-148
gi|124028521 hematopoietic transcription factor PU.1 isoform 1 [...   121   6e-28
gi|124028517 hematopoietic transcription factor PU.1 isoform 2 [...   121   6e-28
gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related) [Hom...   117   7e-27
gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]                    67   2e-11
gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]                     67   2e-11
gi|27436883 ets homologous factor [Homo sapiens]                       62   4e-10
gi|6912580 SAM pointed domain containing ets transcription facto...    59   3e-09
gi|187608767 E74-like factor 4 [Homo sapiens]                          58   9e-09
gi|4503555 E74-like factor 4 [Homo sapiens]                            58   9e-09
gi|27363484 E74-like factor 1 (ets domain transcription factor) ...    58   9e-09
gi|223941929 E74-like factor 1 (ets domain transcription factor)...    58   9e-09
gi|4503611 ets variant 6 [Homo sapiens]                                56   3e-08
gi|166851840 E74-like factor 3 (ets domain transcription factor,...    56   3e-08
gi|167235023 E74-like factor 3 (ets domain transcription factor,...    56   3e-08
gi|7706731 ets variant 7 [Homo sapiens]                                55   6e-08
gi|42544172 E74-like factor 2 (ets domain transcription factor) ...    54   1e-07
gi|6857816 E74-like factor 2 (ets domain transcription factor) i...    54   1e-07
gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]          54   2e-07
gi|209954808 ets-related isoform 4 [Homo sapiens]                      53   3e-07
gi|4758300 ets-related isoform 2 [Homo sapiens]                        53   3e-07
gi|33667107 ets-related isoform 1 [Homo sapiens]                       53   3e-07
gi|209954797 ets-related isoform 3 [Homo sapiens]                      53   3e-07
gi|153791178 ets variant gene 2 [Homo sapiens]                         52   4e-07
gi|34452721 GA binding protein transcription factor, alpha subun...    52   5e-07
gi|223718207 ets variant gene 3 isoform 1 [Homo sapiens]               50   1e-06
gi|20270188 ets variant gene 3 isoform 2 [Homo sapiens]                50   1e-06
gi|51972258 ets variant 3-like [Homo sapiens]                          50   1e-06
gi|8923789 FEV (ETS oncogene family) [Homo sapiens]                    48   9e-06
gi|166362732 ELK1 protein [Homo sapiens]                               47   2e-05

>gi|22748707 Spi-C transcription factor (Spi-1/PU.1 related) [Homo
           sapiens]
          Length = 248

 Score =  520 bits (1340), Expect = e-148
 Identities = 248/248 (100%), Positives = 248/248 (100%)

Query: 1   MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE 60
           MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE
Sbjct: 1   MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE 60

Query: 61  EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES 120
           EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES
Sbjct: 61  EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES 120

Query: 121 LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG 180
           LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG
Sbjct: 121 LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG 180

Query: 181 EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY 240
           EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY
Sbjct: 181 EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY 240

Query: 241 HELNHHDC 248
           HELNHHDC
Sbjct: 241 HELNHHDC 248


>gi|124028521 hematopoietic transcription factor PU.1 isoform 1
           [Homo sapiens]
          Length = 271

 Score =  121 bits (303), Expect = 6e-28
 Identities = 60/104 (57%), Positives = 78/104 (75%), Gaps = 1/104 (0%)

Query: 97  PTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGK 156
           P LL  + G  +KK+RL+++L + L + +M   I WVDK KG FQF SK+KE LA  WG 
Sbjct: 158 PGLLPGETGS-KKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGI 216

Query: 157 RKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQR 200
           +KGNRK MTYQKMARALRNYG++GE+ K+++KLTYQFS  +L R
Sbjct: 217 QKGNRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGR 260


>gi|124028517 hematopoietic transcription factor PU.1 isoform 2
           [Homo sapiens]
          Length = 270

 Score =  121 bits (303), Expect = 6e-28
 Identities = 60/104 (57%), Positives = 78/104 (75%), Gaps = 1/104 (0%)

Query: 97  PTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGK 156
           P LL  + G  +KK+RL+++L + L + +M   I WVDK KG FQF SK+KE LA  WG 
Sbjct: 157 PGLLPGETGS-KKKIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGI 215

Query: 157 RKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQR 200
           +KGNRK MTYQKMARALRNYG++GE+ K+++KLTYQFS  +L R
Sbjct: 216 QKGNRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGR 259


>gi|61888836 Spi-B transcription factor (Spi-1/PU.1 related) [Homo
           sapiens]
          Length = 262

 Score =  117 bits (294), Expect = 7e-27
 Identities = 57/99 (57%), Positives = 73/99 (73%), Gaps = 5/99 (5%)

Query: 105 GKG-----RKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKG 159
           GKG     RKKLRL+++L   L   +M  C+ WV+   G+FQF SK+KE LA  WG++KG
Sbjct: 158 GKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKG 217

Query: 160 NRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAIL 198
           NRK MTYQK+ARALRNY ++GEI K++RKLTYQF  A+L
Sbjct: 218 NRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALL 256


>gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]
          Length = 265

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 33/84 (39%), Positives = 58/84 (69%), Gaps = 4/84 (4%)

Query: 113 LFEYLHESLYNPEM-ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMAR 171
           L+E++ + L +PE     ++W D+ +GIF+ V    E LA++WG+RK N + MTY+K++R
Sbjct: 175 LWEFVRDLLLSPEENCGILEWEDREQGIFRVVKS--EALAKMWGQRKKNDR-MTYEKLSR 231

Query: 172 ALRNYGRSGEITKIRRKLTYQFSE 195
           ALR Y ++G + ++ R+L Y+F +
Sbjct: 232 ALRYYYKTGILERVDRRLVYKFGK 255


>gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]
          Length = 255

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 33/84 (39%), Positives = 58/84 (69%), Gaps = 4/84 (4%)

Query: 113 LFEYLHESLYNPEM-ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMAR 171
           L+E++ + L +PE     ++W D+ +GIF+ V    E LA++WG+RK N + MTY+K++R
Sbjct: 165 LWEFVRDLLLSPEENCGILEWEDREQGIFRVVKS--EALAKMWGQRKKNDR-MTYEKLSR 221

Query: 172 ALRNYGRSGEITKIRRKLTYQFSE 195
           ALR Y ++G + ++ R+L Y+F +
Sbjct: 222 ALRYYYKTGILERVDRRLVYKFGK 245


>gi|27436883 ets homologous factor [Homo sapiens]
          Length = 300

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 31/85 (36%), Positives = 58/85 (68%), Gaps = 5/85 (5%)

Query: 113 LFEYLHESLYNPEM-ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMAR 171
           L+E++ + L NP+     I+W D+++G+F+F+    E +A+LWGK+K N  +MTY+K++R
Sbjct: 209 LWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKS--EAVAQLWGKKKNN-SSMTYEKLSR 265

Query: 172 ALRNYGRSGEITKI-RRKLTYQFSE 195
           A+R Y +   + ++  R+L Y+F +
Sbjct: 266 AMRYYYKREILERVDGRRLVYKFGK 290


>gi|6912580 SAM pointed domain containing ets transcription factor
           [Homo sapiens]
          Length = 335

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 35/90 (38%), Positives = 54/90 (60%), Gaps = 6/90 (6%)

Query: 111 LRLFEYLHESLYNPEM-ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKM 169
           + L+++L E L  P      I+W++K KGIF+   ++  ++A LWG RK NR  M Y K+
Sbjct: 249 IHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKI--EDSAQVARLWGIRK-NRPAMNYDKL 305

Query: 170 ARALRNYGRSGEITK--IRRKLTYQFSEAI 197
           +R++R Y + G I K  I ++L YQF   I
Sbjct: 306 SRSIRQYYKKGIIRKPDISQRLVYQFVHPI 335


>gi|187608767 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 37/101 (36%), Positives = 58/101 (57%), Gaps = 6/101 (5%)

Query: 97  PTLLQQKGGKGRKKLRLFEYLHESLYNPEMA-SCIQWVDKTKGIFQFVSKNKEKLAELWG 155
           P   + K GKG   + L+E+L   L +       I+W  + KGIF+ V  + + +++LWG
Sbjct: 196 PIRKKSKDGKG-STIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLV--DSKAVSKLWG 252

Query: 156 KRKGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFSE 195
           K+K N+  M Y+ M RALR Y + G + K+  ++L YQF E
Sbjct: 253 KQK-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKE 292


>gi|4503555 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 37/101 (36%), Positives = 58/101 (57%), Gaps = 6/101 (5%)

Query: 97  PTLLQQKGGKGRKKLRLFEYLHESLYNPEMA-SCIQWVDKTKGIFQFVSKNKEKLAELWG 155
           P   + K GKG   + L+E+L   L +       I+W  + KGIF+ V  + + +++LWG
Sbjct: 196 PIRKKSKDGKG-STIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLV--DSKAVSKLWG 252

Query: 156 KRKGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFSE 195
           K+K N+  M Y+ M RALR Y + G + K+  ++L YQF E
Sbjct: 253 KQK-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKE 292


>gi|27363484 E74-like factor 1 (ets domain transcription factor)
           isoform a [Homo sapiens]
          Length = 619

 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 10/99 (10%)

Query: 101 QQKGGKGRKKLRLFEYLHESLYNPEMASC---IQWVDKTKGIFQFVSKNKEKLAELWGKR 157
           + K GKG   + L+E+L   L   + A+C   I+W  + KGIF+ V  + + ++ LWGK 
Sbjct: 199 KNKDGKGNT-IYLWEFLLALLQ--DKATCPKYIKWTQREKGIFKLV--DSKAVSRLWGKH 253

Query: 158 KGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFSE 195
           K N+  M Y+ M RALR Y + G + K+  ++L YQF E
Sbjct: 254 K-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKE 291


>gi|223941929 E74-like factor 1 (ets domain transcription factor)
           isoform b [Homo sapiens]
          Length = 595

 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 10/99 (10%)

Query: 101 QQKGGKGRKKLRLFEYLHESLYNPEMASC---IQWVDKTKGIFQFVSKNKEKLAELWGKR 157
           + K GKG   + L+E+L   L   + A+C   I+W  + KGIF+ V  + + ++ LWGK 
Sbjct: 175 KNKDGKGNT-IYLWEFLLALLQ--DKATCPKYIKWTQREKGIFKLV--DSKAVSRLWGKH 229

Query: 158 KGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFSE 195
           K N+  M Y+ M RALR Y + G + K+  ++L YQF E
Sbjct: 230 K-NKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKE 267


>gi|4503611 ets variant 6 [Homo sapiens]
          Length = 452

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 31/72 (43%), Positives = 44/72 (61%), Gaps = 3/72 (4%)

Query: 113 LFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARA 172
           L++Y+++ L +    + I+W DK   IF+ V  N   LA LWG  K NR  MTY+KM+RA
Sbjct: 341 LWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNG--LARLWGNHK-NRTNMTYEKMSRA 397

Query: 173 LRNYGRSGEITK 184
           LR+Y +   I K
Sbjct: 398 LRHYYKLNIIRK 409


>gi|166851840 E74-like factor 3 (ets domain transcription factor,
           epithelial-specific ) [Homo sapiens]
          Length = 371

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 28/85 (32%), Positives = 57/85 (67%), Gaps = 5/85 (5%)

Query: 113 LFEYLHESLYNPEM-ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMAR 171
           L+E++ + L +PE+    ++W ++ +G+F+F+    E +A+LWG++K N   MTY+K++R
Sbjct: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFL--RSEAVAQLWGQKKKN-SNMTYEKLSR 331

Query: 172 ALRNYGRSGEITKI-RRKLTYQFSE 195
           A+R Y +   + ++  R+L Y+F +
Sbjct: 332 AMRYYYKREILERVDGRRLVYKFGK 356


>gi|167235023 E74-like factor 3 (ets domain transcription factor,
           epithelial-specific ) [Homo sapiens]
          Length = 371

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 28/85 (32%), Positives = 57/85 (67%), Gaps = 5/85 (5%)

Query: 113 LFEYLHESLYNPEM-ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMAR 171
           L+E++ + L +PE+    ++W ++ +G+F+F+    E +A+LWG++K N   MTY+K++R
Sbjct: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFL--RSEAVAQLWGQKKKN-SNMTYEKLSR 331

Query: 172 ALRNYGRSGEITKI-RRKLTYQFSE 195
           A+R Y +   + ++  R+L Y+F +
Sbjct: 332 AMRYYYKREILERVDGRRLVYKFGK 356


>gi|7706731 ets variant 7 [Homo sapiens]
          Length = 341

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 34/82 (41%), Positives = 49/82 (59%), Gaps = 4/82 (4%)

Query: 113 LFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARA 172
           L++Y+++ L +      I+W DK   IF+ V  N   LA LWG  K NR  MTY+KM+RA
Sbjct: 226 LWDYVYQLLLDTRYEPYIKWEDKDAKIFRVVDPNG--LARLWGNHK-NRVNMTYEKMSRA 282

Query: 173 LRNYGRSGEITK-IRRKLTYQF 193
           LR+Y +   I K   +KL ++F
Sbjct: 283 LRHYYKLNIIKKEPGQKLLFRF 304


>gi|42544172 E74-like factor 2 (ets domain transcription factor)
           isoform 1 [Homo sapiens]
          Length = 581

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 6/93 (6%)

Query: 105 GKGRKKLRLFEYLHESLYNPEMAS-CIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKT 163
           GKG     L+E+L + L +       I+W  + KGIF+ V  + + +++LWGK K N+  
Sbjct: 191 GKGNTTY-LWEFLLDLLQDKNTCPRYIKWTQREKGIFKLV--DSKAVSKLWGKHK-NKPD 246

Query: 164 MTYQKMARALRNYGRSGEITKIR-RKLTYQFSE 195
           M Y+ M RALR Y + G + K+  ++L YQF +
Sbjct: 247 MNYETMGRALRYYYQRGILAKVEGQRLVYQFKD 279


>gi|6857816 E74-like factor 2 (ets domain transcription factor)
           isoform 2 [Homo sapiens]
          Length = 533

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 6/93 (6%)

Query: 105 GKGRKKLRLFEYLHESLYNPEMAS-CIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKT 163
           GKG     L+E+L + L +       I+W  + KGIF+ V  + + +++LWGK K N+  
Sbjct: 143 GKGNTTY-LWEFLLDLLQDKNTCPRYIKWTQREKGIFKLV--DSKAVSKLWGKHK-NKPD 198

Query: 164 MTYQKMARALRNYGRSGEITKIR-RKLTYQFSE 195
           M Y+ M RALR Y + G + K+  ++L YQF +
Sbjct: 199 MNYETMGRALRYYYQRGILAKVEGQRLVYQFKD 231


>gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]
          Length = 452

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 37/113 (32%), Positives = 63/113 (55%), Gaps = 7/113 (6%)

Query: 93  QLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAE 152
           Q++ PT   +    G  +++L+++L E L +   ASCI W + T G F+    + +++A 
Sbjct: 264 QILGPTS-SRLANPGSGQIQLWQFLLELLSDSANASCITW-EGTNGEFKMT--DPDEVAR 319

Query: 153 LWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFS-EAILQRLSP 203
            WG+RK ++  M Y K++RALR Y     +TK+  ++  Y+F    I Q L P
Sbjct: 320 RWGERK-SKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 371


>gi|209954808 ets-related isoform 4 [Homo sapiens]
          Length = 387

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 36/113 (31%), Positives = 63/113 (55%), Gaps = 7/113 (6%)

Query: 93  QLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAE 152
           Q++ PT   +    G  +++L+++L E L +   +SCI W + T G F+    + +++A 
Sbjct: 202 QILGPTS-SRLANPGSGQIQLWQFLLELLSDSSNSSCITW-EGTNGEFKMT--DPDEVAR 257

Query: 153 LWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFS-EAILQRLSP 203
            WG+RK ++  M Y K++RALR Y     +TK+  ++  Y+F    I Q L P
Sbjct: 258 RWGERK-SKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 309


>gi|4758300 ets-related isoform 2 [Homo sapiens]
          Length = 462

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 36/113 (31%), Positives = 63/113 (55%), Gaps = 7/113 (6%)

Query: 93  QLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAE 152
           Q++ PT   +    G  +++L+++L E L +   +SCI W + T G F+    + +++A 
Sbjct: 277 QILGPTS-SRLANPGSGQIQLWQFLLELLSDSSNSSCITW-EGTNGEFKMT--DPDEVAR 332

Query: 153 LWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFS-EAILQRLSP 203
            WG+RK ++  M Y K++RALR Y     +TK+  ++  Y+F    I Q L P
Sbjct: 333 RWGERK-SKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 384


>gi|33667107 ets-related isoform 1 [Homo sapiens]
          Length = 479

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 36/113 (31%), Positives = 63/113 (55%), Gaps = 7/113 (6%)

Query: 93  QLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAE 152
           Q++ PT   +    G  +++L+++L E L +   +SCI W + T G F+    + +++A 
Sbjct: 294 QILGPTS-SRLANPGSGQIQLWQFLLELLSDSSNSSCITW-EGTNGEFKMT--DPDEVAR 349

Query: 153 LWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFS-EAILQRLSP 203
            WG+RK ++  M Y K++RALR Y     +TK+  ++  Y+F    I Q L P
Sbjct: 350 RWGERK-SKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 401


>gi|209954797 ets-related isoform 3 [Homo sapiens]
          Length = 486

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 36/113 (31%), Positives = 63/113 (55%), Gaps = 7/113 (6%)

Query: 93  QLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAE 152
           Q++ PT   +    G  +++L+++L E L +   +SCI W + T G F+    + +++A 
Sbjct: 301 QILGPTS-SRLANPGSGQIQLWQFLLELLSDSSNSSCITW-EGTNGEFKMT--DPDEVAR 356

Query: 153 LWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR-RKLTYQFS-EAILQRLSP 203
            WG+RK ++  M Y K++RALR Y     +TK+  ++  Y+F    I Q L P
Sbjct: 357 RWGERK-SKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQP 408


>gi|153791178 ets variant gene 2 [Homo sapiens]
          Length = 342

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 30/87 (34%), Positives = 53/87 (60%), Gaps = 5/87 (5%)

Query: 108 RKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQ 167
           R  ++L+++L E L++   +SCI+W   ++   +F   + +++A LWG+RK  +  M Y+
Sbjct: 238 RGPIQLWQFLLELLHDGARSSCIRWTGNSR---EFQLCDPKEVARLWGERK-RKPGMNYE 293

Query: 168 KMARALRNYGRSGEITKI-RRKLTYQF 193
           K++R LR Y R   + K   RK TY+F
Sbjct: 294 KLSRGLRYYYRRDIVRKSGGRKYTYRF 320


>gi|34452721 GA binding protein transcription factor, alpha subunit
           [Homo sapiens]
          Length = 454

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 29/85 (34%), Positives = 50/85 (58%), Gaps = 5/85 (5%)

Query: 110 KLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKM 169
           +++L+++L E L + +   CI WV       +F     E +A+ WG+RK N+ TM Y+K+
Sbjct: 319 QIQLWQFLLELLTDKDARDCISWVGDEG---EFKLNQPELVAQKWGQRK-NKPTMNYEKL 374

Query: 170 ARALRNYGRSGEITKIR-RKLTYQF 193
           +RALR Y     I K++ ++  Y+F
Sbjct: 375 SRALRYYYDGDMICKVQGKRFVYKF 399


>gi|223718207 ets variant gene 3 isoform 1 [Homo sapiens]
          Length = 512

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 4/89 (4%)

Query: 107 GRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTY 166
           G ++++L+ ++ E L   E    I W     G  +FV K+ +++A LWG+RK  +  M Y
Sbjct: 31  GSRQIQLWHFILELLQKEEFRHVIAWQQGEYG--EFVIKDPDEVARLWGRRK-CKPQMNY 87

Query: 167 QKMARALRNYGRSGEITKIR-RKLTYQFS 194
            K++RALR Y     + K + ++ TY+F+
Sbjct: 88  DKLSRALRYYYNKRILHKTKGKRFTYKFN 116


>gi|20270188 ets variant gene 3 isoform 2 [Homo sapiens]
          Length = 143

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 4/89 (4%)

Query: 107 GRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTY 166
           G ++++L+ ++ E L   E    I W     G  +FV K+ +++A LWG+RK  +  M Y
Sbjct: 31  GSRQIQLWHFILELLQKEEFRHVIAWQQGEYG--EFVIKDPDEVARLWGRRK-CKPQMNY 87

Query: 167 QKMARALRNYGRSGEITKIR-RKLTYQFS 194
            K++RALR Y     + K + ++ TY+F+
Sbjct: 88  DKLSRALRYYYNKRILHKTKGKRFTYKFN 116


>gi|51972258 ets variant 3-like [Homo sapiens]
          Length = 361

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 4/89 (4%)

Query: 107 GRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTY 166
           G ++++L+ ++ E L   E    I W     G  +FV K+ +++A LWG+RK  +  M Y
Sbjct: 35  GSRQIQLWHFILELLQKEEFRHVIAWQQGEYG--EFVIKDPDEVARLWGRRK-CKPQMNY 91

Query: 167 QKMARALRNYGRSGEITKIR-RKLTYQFS 194
            K++RALR Y     + K + ++ TY+F+
Sbjct: 92  DKLSRALRYYYNKRILHKTKGKRFTYKFN 120


>gi|8923789 FEV (ETS oncogene family) [Homo sapiens]
          Length = 238

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 30/100 (30%), Positives = 55/100 (55%), Gaps = 6/100 (6%)

Query: 106 KGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMT 165
           KG  +++L+++L E L +   A CI W     G  +F   + +++A  WG+RK ++  M 
Sbjct: 42  KGSGQIQLWQFLLELLADRANAGCIAW---EGGHGEFKLTDPDEVARRWGERK-SKPNMN 97

Query: 166 YQKMARALRNYGRSGEITKIR-RKLTYQFS-EAILQRLSP 203
           Y K++RALR Y     ++K+  ++  Y+F  + + Q   P
Sbjct: 98  YDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQGLAQACQP 137


>gi|166362732 ELK1 protein [Homo sapiens]
          Length = 428

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 4/82 (4%)

Query: 113 LFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARA 172
           L+++L + L        I W  +  G F+ V  + E++A LWG RK N+  M Y K++RA
Sbjct: 7   LWQFLLQLLREQGNGHIISWTSRDGGEFKLV--DAEEVARLWGLRK-NKTNMNYDKLSRA 63

Query: 173 LRNYGRSGEITKIR-RKLTYQF 193
           LR Y     I K+  +K  Y+F
Sbjct: 64  LRYYYDKNIIRKVSGQKFVYKF 85


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,789,362
Number of Sequences: 37866
Number of extensions: 416977
Number of successful extensions: 892
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 846
Number of HSP's gapped (non-prelim): 55
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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