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Search of human proteins with 226958547
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo
sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens] 750 0.0
gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens] 657 0.0
gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens] 657 0.0
gi|19923629 Fc receptor-like 2 precursor [Homo sapiens] 379 e-105
gi|21314764 Fc receptor-like 3 precursor [Homo sapiens] 340 1e-93
gi|157694526 Fc receptor-like 5 [Homo sapiens] 207 1e-53
gi|14550416 Fc receptor-like 4 precursor [Homo sapiens] 179 5e-45
gi|157057547 Fc receptor-like 6 [Homo sapiens] 112 5e-25
gi|15147240 brother of CDO [Homo sapiens] 68 1e-11
gi|13489095 sialoadhesin precursor [Homo sapiens] 67 3e-11
gi|110349719 titin isoform N2-A [Homo sapiens] 65 1e-10
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 65 1e-10
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 65 1e-10
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 65 1e-10
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 63 4e-10
gi|157168355 CD22 molecule [Homo sapiens] 62 6e-10
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 62 1e-09
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 61 1e-09
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 61 2e-09
gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [... 60 2e-09
gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor [... 60 2e-09
gi|118572606 hemicentin 1 [Homo sapiens] 59 7e-09
gi|157819143 IgLON family member 5 [Homo sapiens] 58 1e-08
gi|224994173 roundabout 1 isoform d [Homo sapiens] 57 2e-08
gi|224994171 roundabout 1 isoform c [Homo sapiens] 57 2e-08
gi|19743806 roundabout 1 isoform b [Homo sapiens] 57 2e-08
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 57 2e-08
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 57 2e-08
gi|4506569 roundabout 1 isoform a [Homo sapiens] 57 2e-08
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 56 4e-08
>gi|226958547 Fc receptor-like 1 isoform 2 precursor [Homo sapiens]
Length = 366
Score = 750 bits (1937), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSA 300
WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSA
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSA 300
Query: 301 RDPLRSLPSPLPQEFTYLNSPTPGQLQPIYENEPREQSVAVHGRQQHSSEQKAQKPWGHI 360
RDPLRSLPSPLPQEFTYLNSPTPGQLQPIYENEPREQSVAVHGRQQHSSEQKAQKPWGHI
Sbjct: 301 RDPLRSLPSPLPQEFTYLNSPTPGQLQPIYENEPREQSVAVHGRQQHSSEQKAQKPWGHI 360
Query: 361 WRTRFP 366
WRTRFP
Sbjct: 361 WRTRFP 366
>gi|16418419 Fc receptor-like 1 isoform 1 precursor [Homo sapiens]
Length = 429
Score = 657 bits (1696), Expect = 0.0
Identities = 337/406 (83%), Positives = 342/406 (84%), Gaps = 55/406 (13%)
Query: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT----- 295
WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
Query: 296 ----------------------------------GRRSARDPLRSLPSPLPQEFTYLNSP 321
GRRSARDPLRSLPSPLPQEFTYLNSP
Sbjct: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
Query: 322 TPGQLQPIYE----------------NEPREQSVAVHGRQQHSSEQ 351
TPGQLQPIYE N+P ++SVA H ++
Sbjct: 361 TPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDK 406
>gi|226958551 Fc receptor-like 1 isoform 3 precursor [Homo sapiens]
Length = 428
Score = 657 bits (1695), Expect = 0.0
Identities = 332/371 (89%), Positives = 332/371 (89%), Gaps = 39/371 (10%)
Query: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA
Sbjct: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP
Sbjct: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ
Sbjct: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY
Sbjct: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT----- 295
WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT
Sbjct: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGA 300
Query: 296 ----------------------------------GRRSARDPLRSLPSPLPQEFTYLNSP 321
GRRSARDPLRSLPSPLPQEFTYLNSP
Sbjct: 301 RSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSP 360
Query: 322 TPGQLQPIYEN 332
TPGQLQPIYEN
Sbjct: 361 TPGQLQPIYEN 371
>gi|19923629 Fc receptor-like 2 precursor [Homo sapiens]
Length = 508
Score = 379 bits (974), Expect = e-105
Identities = 202/355 (56%), Positives = 247/355 (69%), Gaps = 44/355 (12%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
L AS P EG PV+L C+ Q D Q QFCFFR+ + LG GWSSSP+LQI+A+W E
Sbjct: 111 LTASSFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRENQVLGSGWSSSPELQISAVWSE 170
Query: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
DTGSYWC+A+T+ ++ + S +SQI+V R+P+++VSLE + PGGQV EG +L+L+CSVA
Sbjct: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
GTG++TF WY+ A G ++ KTQRSL+AE EIP+V+ESDA +YYC A+NG+ P S +V+
Sbjct: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVVN 290
Query: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
I VRIPVSRP+L LR+P AQAAV D+LELHCEALRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 291 IPVRIPVSRPVLTLRSPGAQAAVGDLLELHCEALRGSPPILYQFYHEDVTLGNSSAPSGG 350
Query: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAV-------------------------TLN 293
GASFNLSLT EHSGNYSCEANNGLGAQ SEAV L
Sbjct: 351 GASFNLSLTAEHSGNYSCEANNGLGAQCSEAVPVSISGPDGYRRDLMTAGVLWGLFGVLG 410
Query: 294 FT--------------GRRSARDPLRSLPSPLPQEFTYLNSPTPG--QLQPIYEN 332
FT G SA + R P PQEFTY +SPTP +LQP+Y N
Sbjct: 411 FTGVALLLYALFHKISGESSATNEPRGASRPNPQEFTY-SSPTPDMEELQPVYVN 464
Score = 53.9 bits (128), Expect = 2e-07
Identities = 77/319 (24%), Positives = 127/319 (39%), Gaps = 21/319 (6%)
Query: 1 MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRA 60
ML LL+I + E A+ + +PS EG + L C+ Q+ Q + + +D +
Sbjct: 1 MLLWSLLVIFDAVTEQADSLTLVAPSSVFEGDSIVLKCQGE--QNWKIQ-KMAYHKDNKE 57
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L S L I + D+G+Y+C T L + S I +V
Sbjct: 58 LSVFKKFSDFL-IQSAVLSDSGNYFC--STKGQLFLWDKTSNIVKIKVQELFQRPVLTAS 114
Query: 121 GGQVMEGDRLVLICSVAMGTG----DITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
Q +EG + L C + + F +++ N + S + E +I +V
Sbjct: 115 SFQPIEGGPVSLKCETRLSPQRLDVQLQFCFFRE----NQVLGSGWSSSPELQISAVWSE 170
Query: 177 DAEQYYCVAENGYGPSPSGLVSITV---RIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
D Y+C AE + + RIP+S L +RAP Q L L C
Sbjct: 171 DTGSYWCKAETVTHRIRKQSLQSQIHVQRIPISNVSLEIRAPGGQVTEGQKLILLCSVAG 230
Query: 234 GSPPILYWFYHE--DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVT 291
G+ + + +Y E ++G ++ S ++ E +G Y C A+NG +S+ V
Sbjct: 231 GTGNVTFSWYREATGTSMGKKTQRSLSAELEIPAVKESDAGKYYCRADNGHVPIQSKVV- 289
Query: 292 LNFTGRRSARDPLRSLPSP 310
N R P+ +L SP
Sbjct: 290 -NIPVRIPVSRPVLTLRSP 307
>gi|21314764 Fc receptor-like 3 precursor [Homo sapiens]
Length = 734
Score = 340 bits (872), Expect = 1e-93
Identities = 170/277 (61%), Positives = 207/277 (74%), Gaps = 2/277 (0%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
L AS S P EGSP+TLTC+ Q D Q QF FRD++ LG GWS SP+LQI AMW E
Sbjct: 194 LRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTE 253
Query: 80 DTGSYWCEAQTMASKVL-RSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
D+GSYWCE +T+ + RS RSQI V RVPV++V+LE +P GGQ++EG+ +VLICSVA
Sbjct: 254 DSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQ 313
Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
G+G +TF W+K +L KTQRSL AE + +V+ESDA +YYC A+N + P S +
Sbjct: 314 GSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIR 373
Query: 199 ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
+TVRIPVS P+L RAPRA V D+LELHCE+LRGSPPILY FYHED+TLG+ SAPSGG
Sbjct: 374 VTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGG 433
Query: 259 GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT 295
GASFNLSLT EHSGNYSC+A+NGLGAQ S V+L T
Sbjct: 434 GASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVT 470
Score = 197 bits (502), Expect = 9e-51
Identities = 148/394 (37%), Positives = 190/394 (48%), Gaps = 76/394 (19%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSS--PKLQIAAMWKEDTGSYWCE 87
EG + L C + S F + R+LG S +L + + + D G Y+C
Sbjct: 301 EGENMVLICSVA-QGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCA 359
Query: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
A + S +L S ++ V R+PV+ L + P + GD L L C G+ I + +
Sbjct: 360 ADNVHSPIL-STWIRVTV-RIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRF 417
Query: 148 YKGAVGLNLQSKTQR-------SLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
Y V L S SLTAE+ + Y C A+NG G S VS+
Sbjct: 418 YHEDVTLGNSSAPSGGGASFNLSLTAEH---------SGNYSCDADNGLGAQHSHGVSLR 468
Query: 201 VRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGA 260
V +PVSRP+L LRAP AQA V D+LELHCE+LRGS PILYWFYHED TLG+ SA SGGGA
Sbjct: 469 VTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGA 528
Query: 261 SFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTG------------------------ 296
SFNLSLT EHSGNYSCEA+NGLGAQ S+ VTLN TG
Sbjct: 529 SFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLA 588
Query: 297 -----------RR----------------SARDPLRSLPSPL-PQEFTYLNSPTPGQLQP 328
RR ++P S PS + PQE T+ P +L+P
Sbjct: 589 AAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEP 648
Query: 329 IYENEPREQSVAVHGR---QQHSSEQKAQKPWGH 359
+Y N S ++ + QH+ E A P H
Sbjct: 649 MYSNVNPGDSNPIYSQIWSIQHTKENSANCPMMH 682
>gi|157694526 Fc receptor-like 5 [Homo sapiens]
Length = 977
Score = 207 bits (527), Expect = 1e-53
Identities = 120/278 (43%), Positives = 159/278 (57%), Gaps = 7/278 (2%)
Query: 21 LIASPSHPTEGSPVTLTCKMPF-LQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
L AS P G+PVTLTC+ L+ SD +F FFRD + LG GWS SP QI AMW +
Sbjct: 194 LRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSK 253
Query: 80 DTGSYWCEAQTMASKVLR-SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
D+G YWC+A TM V+ S RS I V ++P + L P EG ++ L C
Sbjct: 254 DSGFYWCKAATMPYSVISDSPRSWIQV-QIPASHPVLTLSPEKALNFEGTKVTLHCETQE 312
Query: 139 GTGDITFLWYKGAVGLNLQS-KTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
+ + +Y V L +S + +R + + S+ ++ YYC A+NG G PS V
Sbjct: 313 DSLRTLYRFYHEGVPLRHKSVRCERGASISF---SLTTENSGNYYCTADNGLGAKPSKAV 369
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSG 257
S++V +PVS P+L L +P + LHCEA RGS PILY F+HE L RSA S
Sbjct: 370 SLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSA 429
Query: 258 GGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT 295
GG + + SLT EHSGNY C A+NG G QRS+AV+L+ T
Sbjct: 430 GGVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVT 467
Score = 199 bits (507), Expect = 2e-51
Identities = 122/266 (45%), Positives = 159/266 (59%), Gaps = 9/266 (3%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-GWSSSPKLQIA-AMWKEDTGSYWCE 87
EG+ VTL C+ Q + F + AL +S+ + I+ ++ E +G+Y+C
Sbjct: 393 EGAKVTLHCEA---QRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSGNYYCT 449
Query: 88 AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLW 147
A RS+ ++V VPV+ L EG + L C V G+ I + +
Sbjct: 450 ADNGFGPQ-RSKAVSLSV-TVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQF 507
Query: 148 YKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
Y + L S + S+ S+ E + YYC A+NG+GP S +VS+ V +PVSR
Sbjct: 508 YHE--DMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSR 565
Query: 208 PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
PIL LR PRAQA V D+LELHCEA RGSPPILYWFYHED+TLGS SAPSGG ASFNLSLT
Sbjct: 566 PILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLT 625
Query: 268 EEHSGNYSCEANNGLGAQRSEAVTLN 293
EHSGNYSCEANNGL AQ S+ ++L+
Sbjct: 626 AEHSGNYSCEANNGLVAQHSDTISLS 651
Score = 194 bits (493), Expect = 1e-49
Identities = 128/291 (43%), Positives = 166/291 (57%), Gaps = 16/291 (5%)
Query: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
L + P+ P L L ++ + EG+ VTL C++ Q Q + F+ + L WS
Sbjct: 464 LSVTVPVSHPV-LTLSSAEALTFEGATVTLHCEV---QRGSPQILYQFYHEDMPL---WS 516
Query: 67 SSP----KLQIA-AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
SS ++ + ++ + +G+Y+C A RS + V VPV+ L + P
Sbjct: 517 SSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQ-RSEVVSLFV-TVPVSRPILTLRVPR 574
Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Q + GD L L C G+ I + +Y V L S A + + S+ + Y
Sbjct: 575 AQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGG-EASFNL-SLTAEHSGNY 632
Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
C A NG S +S++V +PVSRPIL RAPRAQA V D+LELHCEALRGS PILYW
Sbjct: 633 SCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEALRGSSPILYW 692
Query: 242 FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
FYHED+TLG SAPSGGGASFNLSLT EHSG YSCEA+NGL AQRSE VTL
Sbjct: 693 FYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVTL 743
Score = 191 bits (486), Expect = 7e-49
Identities = 143/379 (37%), Positives = 187/379 (49%), Gaps = 59/379 (15%)
Query: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP--- 63
L + P+ P L L + G + L C+ P + F+ + LG
Sbjct: 557 LFVTVPVSRPI-LTLRVPRAQAVVGDLLELHCEAP---RGSPPILYWFYHEDVTLGSSSA 612
Query: 64 --GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHR-VPVADVSLETQPP 120
G +S L + A E +G+Y CEA + ++ I++ VPV+ L + P
Sbjct: 613 PSGGEASFNLSLTA---EHSGNYSCEAN---NGLVAQHSDTISLSVIVPVSRPILTFRAP 666
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
Q + GD L L C G+ I + +Y V L S A + + S+ +
Sbjct: 667 RAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKISAPSGG-GASFNL-SLTTEHSGI 724
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Y C A+NG S +V++ V +PVSRP+L LRAP AAV D+LELHCEALRGSP ILY
Sbjct: 725 YSCEADNGLEAQRSEMVTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILY 784
Query: 241 WFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFT----- 295
F+HED+TLG+RS+PS GGAS NLSLT EHSGNYSCEA+NGLGAQRSE VTL T
Sbjct: 785 RFFHEDVTLGNRSSPS-GGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTAN 843
Query: 296 ----------------------------------GRRSARDPLRSLPSPLPQEFTYLNSP 321
GR+ A DP RS QE TY N P
Sbjct: 844 RSGPFATGVAGGLLSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVP 903
Query: 322 TPGQLQPIYEN-EPREQSV 339
+LQP+Y N PR ++V
Sbjct: 904 AWEELQPVYTNANPRGENV 922
Score = 148 bits (373), Expect = 9e-36
Identities = 105/306 (34%), Positives = 149/306 (48%), Gaps = 32/306 (10%)
Query: 3 PRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALG 62
PR + + P P L L + EG+ VTL C+ Q + + F+ + L
Sbjct: 274 PRSWIQVQIPASHPV-LTLSPEKALNFEGTKVTLHCET---QEDSLRTLYRFYHEGVPLR 329
Query: 63 PGWSSSPKLQIAA-----MWKEDTGSYWCEAQT-MASKVLRSRRSQINVHRVPVADVSLE 116
S + + A + E++G+Y+C A + +K ++ + V PV+ L
Sbjct: 330 ---HKSVRCERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTV---PVSHPVLN 383
Query: 117 TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQR-------SLTAEYE 169
P + EG ++ L C G+ I + ++ L +S SLTAE+
Sbjct: 384 LSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEH- 442
Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
+ YYC A+NG+GP S VS++V +PVS P+L L + A + LHC
Sbjct: 443 --------SGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHC 494
Query: 230 EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
E RGSP ILY FYHED+ L S S PS G SF+ SLTE HSGNY C A+NG G QRSE
Sbjct: 495 EVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEV 554
Query: 290 VTLNFT 295
V+L T
Sbjct: 555 VSLFVT 560
Score = 29.3 bits (64), Expect = 5.8
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 16/114 (14%)
Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESD 177
QPP V +G+R+ L C WY +G + +T + I V+ES
Sbjct: 28 QPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDN------ILEVQESG 81
Query: 178 AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEA 231
+Y C A+ SP V + S L+L+AP + + V+ L C A
Sbjct: 82 --EYRCQAQGSPLSSP-------VHLDFSSASLILQAPLSVFEGDSVV-LRCRA 125
>gi|14550416 Fc receptor-like 4 precursor [Homo sapiens]
Length = 515
Score = 179 bits (453), Expect = 5e-45
Identities = 89/184 (48%), Positives = 125/184 (67%), Gaps = 2/184 (1%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFL-QSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKE 79
L A+ S PTEG+ V L+C+ + SD F FFRD + WS+ P+LQ+ +W+E
Sbjct: 195 LKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRE 254
Query: 80 DTGSYWCEAQTMASKVLRSRRS-QINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
++GSYWC A+T+ + + S QI+V R+PV+ V LETQP GGQ +EG+ LVL+CSVA
Sbjct: 255 NSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAE 314
Query: 139 GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
GTGD TF W++ + +L KTQRSL AE E+P++R+S A YYC A+N YGP S +++
Sbjct: 315 GTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLN 374
Query: 199 ITVR 202
+TVR
Sbjct: 375 VTVR 378
Score = 51.2 bits (121), Expect = 1e-06
Identities = 40/139 (28%), Positives = 69/139 (49%), Gaps = 9/139 (6%)
Query: 167 EYEIPSVRESDAEQYYCVAE----NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE 222
E ++P+V ++ Y+C AE N + SPS + + RIPVS +L + QA
Sbjct: 245 ELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQ-RIPVSGVLLETQPSGGQAVEG 303
Query: 223 DVLELHCEALRGSPPILYWFYHEDI--TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANN 280
++L L C G+ + ++ ED+ +LG ++ S ++ + H+G Y C A+N
Sbjct: 304 EMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADN 363
Query: 281 GLGAQRSEAVTLNFTGRRS 299
G +S + LN T R +
Sbjct: 364 SYGPVQS--MVLNVTVRET 380
>gi|157057547 Fc receptor-like 6 [Homo sapiens]
Length = 434
Score = 112 bits (280), Expect = 5e-25
Identities = 91/286 (31%), Positives = 136/286 (47%), Gaps = 17/286 (5%)
Query: 19 LFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWK 78
L+L A P+ EG +TL C+ + Q F+RD + L + L + A
Sbjct: 20 LYLQAWPNPVFEGDALTLRCQG---WKNTPLSQVKFYRDGKFLHFS-KENQTLSMGAATV 75
Query: 79 EDTGSYWCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLICSVA 137
+ G Y C Q M ++ S+ + +V + + + P + EG + L C
Sbjct: 76 QSRGQYSCSGQVMYIPQTFTQTSETAMVQVQELFPPPVLSAIPSPEPREGSLVTLRCQTK 135
Query: 138 M----GTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC--VAENGYGP 191
+ + F ++K G LQ R E IP +E D+ Y+C E G
Sbjct: 136 LHPLRSALRLLFSFHKD--GHTLQD---RGPHPELCIPGAKEGDSGLYWCEVAPEGGQVQ 190
Query: 192 SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGS 251
S + + V+ PVSRP+L L A AV D+++L CEA RGSPPILY FY ++ +G+
Sbjct: 191 KQSPQLEVRVQAPVSRPVLTLHHGPADPAVGDMVQLLCEAQRGSPPILYSFYLDEKIVGN 250
Query: 252 RSAPSGGGASFNLSL-TEEHSGNYSCEANNGLGAQRSEAVTLNFTG 296
SAP GG S + +E+ +GNYSCEA N + +RSE L+ G
Sbjct: 251 HSAPCGGTTSLLFPVKSEQDAGNYSCEAENSVSRERSEPKKLSLKG 296
>gi|15147240 brother of CDO [Homo sapiens]
Length = 1114
Score = 67.8 bits (164), Expect = 1e-11
Identities = 69/266 (25%), Positives = 110/266 (41%), Gaps = 19/266 (7%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG---WSSSPKLQIAAMWKEDTGSYWC 86
EG+ + C +P AQ ++ ++ G S LQI +ED G Y C
Sbjct: 142 EGNTAVIACHLPESHPK-AQVRYSVKQEWLEASRGNYLIMPSGNLQIVNASQEDEGMYKC 200
Query: 87 EAQTMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQ---VMEGDRLVLICSVAMGTGD 142
A ++ +++ S + R A+ + PP Q V +G L+L C VA G
Sbjct: 201 AAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILEC-VASGIPP 259
Query: 143 ITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVR 202
W K + +KT R L + I + E D+ Y C+A+NG G + ++ V+
Sbjct: 260 PRVTWAKDGSSVTGYNKT-RFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQ 318
Query: 203 I----PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGG 258
+ V+ + L P Q+A +L CE PP + W + + S+
Sbjct: 319 VFEPPEVTMELSQLVIPWGQSA-----KLTCEVRGNPPPSVLWLRNAVPLISSQRLRLSR 373
Query: 259 GASFNLSLTEEHSGNYSCEANNGLGA 284
A LS+ E G Y C A N +G+
Sbjct: 374 RALRVLSMGPEDEGVYQCMAENEVGS 399
Score = 32.0 bits (71), Expect = 0.90
Identities = 53/235 (22%), Positives = 81/235 (34%), Gaps = 21/235 (8%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I A+ G Y C A+ A V + V + D L+ Q +V EG+
Sbjct: 91 LVITALNNHTVGRYQCVARMPAGAVASVPAT---VTLANLQDFKLDVQHVI-EVDEGNTA 146
Query: 131 VLICSV------AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCV 184
V+ C + A + W + + G L + +I + + D Y C
Sbjct: 147 VIACHLPESHPKAQVRYSVKQEWLEASRGNYLIMPS-----GNLQIVNASQEDEGMYKCA 201
Query: 185 AENGYGPSPSGLVS---ITVRIPVSRPILMLRAPRAQAAVE---DVLELHCEALRGSPPI 238
A N S + VR + ++ P AQ + L L C A PP
Sbjct: 202 AYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPR 261
Query: 239 LYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
+ W G + +EE SG Y C A+NG+G + + N
Sbjct: 262 VTWAKDGSSVTGYNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVILYN 316
>gi|13489095 sialoadhesin precursor [Homo sapiens]
Length = 1709
Score = 67.0 bits (162), Expect = 3e-11
Identities = 79/287 (27%), Positives = 114/287 (39%), Gaps = 50/287 (17%)
Query: 59 RALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQ 118
R G +S +L+I + + D+G Y C A + N R+ ++
Sbjct: 464 RFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLGNATSTLDFHANAARLLIS------- 516
Query: 119 PPGGQVMEGDRLVLICSVAMG-TGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESD 177
P +V+EG + L C + T D F WY G L SL +P+ +D
Sbjct: 517 -PAAEVVEGQAVTLSCRSGLSPTPDARFSWYLN--GALLHEGPGSSLL----LPAASSTD 569
Query: 178 AEQYYCVAENGYGPS-PSGLVSITVRIPVSRPI----LMLRAPRAQAAVEDVLELHCEAL 232
A Y+C A +G+ S PS +TV P +P L L A A A +L ++
Sbjct: 570 AGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAAGAGAGRRGLLLCRVDS- 628
Query: 233 RGSPPILYWFYHEDITLGSRSAPSGGGASF--------------NLSLTEEHS------G 272
PP H+D + + S PSGGG S NL E H+ G
Sbjct: 629 --DPPARLQLLHKDRVVAT-SLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLLEEEG 685
Query: 273 NYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSLPSPLPQEFTYLN 319
Y CEA+N LG + + + F G+ + L PS QE T N
Sbjct: 686 LYLCEASNALG---NASTSATFNGQATV---LAIAPSHTLQEGTEAN 726
Score = 60.8 bits (146), Expect = 2e-09
Identities = 78/295 (26%), Positives = 118/295 (40%), Gaps = 42/295 (14%)
Query: 16 PAELFLIASPS--HPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQI 73
P + ++ SPS + G VTLTC++ S A + +D L + + L +
Sbjct: 238 PKGVKILLSPSGRNILPGELVTLTCQVN--SSYPAVSSIKWLKDGVRLQ---TKTGVLHL 292
Query: 74 AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLI 133
D G Y C+A+ ++ I++H + +A+V + P G ++E + L+
Sbjct: 293 PQAAWSDAGVYTCQAENGVGSLVSP---PISLH-IFMAEVQVS---PAGPILENQTVTLV 345
Query: 134 CSVAM-GTGDITFLWYKGAVGL-NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGP 191
C+ D+ + WYK V L + S T R A +D Y+C +N +G
Sbjct: 346 CNTPNEAPSDLRYSWYKNHVLLEDAHSHTLRLHLAT-------RADTGFYFCEVQNVHGS 398
Query: 192 SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGS 251
SG VS+ V P P+L QA + + LHC + P H L S
Sbjct: 399 ERSGPVSVVVNHPPLTPVLTAFL-ETQAGLVGI--LHCSVV-SEPLATLVLSHGGHILAS 454
Query: 252 RSAPSGGGASFN------------LSLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
S S F+ L E SG Y C A N LG S TL+F
Sbjct: 455 TSGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLGNATS---TLDF 506
Score = 56.6 bits (135), Expect = 3e-08
Identities = 71/291 (24%), Positives = 109/291 (37%), Gaps = 48/291 (16%)
Query: 22 IASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDT 81
IASP EG+ V C P++ C R G + + + E T
Sbjct: 144 IASPVELLEGTEVDFNCSTPYV---------CLQEQVRLQWQGQDPARSVTFNSQKFEPT 194
Query: 82 GSYWCEAQTMA------SKVLR------SRRSQINVH---RVPVADVSLETQPPGGQVME 126
G E MA ++LR + R+Q +H + V + P G ++
Sbjct: 195 GVGHLETLHMAMSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNILP 254
Query: 127 GDRLVLICSVAMGTGDITFL-WYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
G+ + L C V ++ + W K G+ LQ+K T +P SDA Y C A
Sbjct: 255 GELVTLTCQVNSSYPAVSSIKWLKD--GVRLQTK-----TGVLHLPQAAWSDAGVYTCQA 307
Query: 186 ENGYGPSPSGLVSITVRIPVSRPILMLR---APRAQAAVEDVLELHCEALRGSPPILYWF 242
ENG G V P+S I M +P + L C +P L +
Sbjct: 308 ENGVGS--------LVSPPISLHIFMAEVQVSPAGPILENQTVTLVCNTPNEAPSDLRYS 359
Query: 243 YHEDITLGSRSAPSGGGASFNLSL-TEEHSGNYSCEANNGLGAQRSEAVTL 292
++++ L + L L T +G Y CE N G++RS V++
Sbjct: 360 WYKNHVL----LEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSV 406
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/219 (25%), Positives = 85/219 (38%), Gaps = 36/219 (16%)
Query: 83 SYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGD 142
+Y C AQ + + R Q+ RV VA+ PG V EG L L C + G G
Sbjct: 1422 TYVCTAQNLLGSISTIGRLQVEGARV-VAE-------PGLDVPEGAALNLSCRLLGGPGP 1473
Query: 143 I---TFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSI 199
+ TF W+ L+ + + T V + A Y+C+AE G + S V +
Sbjct: 1474 VGNSTFAWFWNDRRLHAEPVPTLAFT------HVARAQAGMYHCLAELPTGAAASAPVML 1527
Query: 200 TVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGG 259
V P P +M+ + + +L+ + S P+ H L + S P G
Sbjct: 1528 RVLYPPKTPTMMVFV-EPEGGLRGILDCRVD----SEPLASLTLHLGSRLVASSQPQGAP 1582
Query: 260 ASFNL--------------SLTEEHSGNYSCEANNGLGA 284
A ++ +L G Y C A+N LG+
Sbjct: 1583 AEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLGS 1621
Score = 46.6 bits (109), Expect = 4e-05
Identities = 57/245 (23%), Positives = 91/245 (37%), Gaps = 41/245 (16%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
++S KL++ + D+GSY CEA + S Q+ V V+ P ++
Sbjct: 856 ANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVS--------PSPELQ 907
Query: 126 EGDRLVLICSVAMGTGDIT-FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCV 184
EG +VL C V G + T + WY+ L Q S +A ++ + A Y+C
Sbjct: 908 EGQAVVLSCQVHTGVPEGTSYRWYRDGQPL------QESTSATLRFAAITLTQAGAYHCQ 961
Query: 185 AENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV----LELHCEALRGSPPILY 240
A+ G + ++ P+S + + D L L + PP
Sbjct: 962 AQ------APGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLLCRVDSDPPAQL 1015
Query: 241 WFYHED----ITLGSRSAPSGGGASFNLSLTE------------EHSGNYSCEANNGLGA 284
H D TL P G ++++ E G Y CEA+N LG
Sbjct: 1016 RLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQ 1075
Query: 285 QRSEA 289
+ A
Sbjct: 1076 ASASA 1080
Score = 45.1 bits (105), Expect = 1e-04
Identities = 72/299 (24%), Positives = 120/299 (40%), Gaps = 62/299 (20%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKED 80
++A + EG+P+T+TC P ++ A + ++ + R L G ++S +A +
Sbjct: 1264 ILAPEAAVPEGAPITVTCADP---AAHAPTLYTWYHNGRWLQEGPAASLSFLVAT--RAH 1318
Query: 81 TGSYWCEAQTMASKVLRSRRSQINVHRVP-----------------VADVSLETQPPGGQ 123
G+Y C+AQ A SR + + V P V +++++PP
Sbjct: 1319 AGAYSCQAQD-AQGTRSSRPAALQVLYAPQDAVLSSFRDSRARSMAVIQCTVDSEPPAEL 1377
Query: 124 VMEGDRLVL-----ICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
+ D VL + S+A GTG + + A+ L +Q ++P +
Sbjct: 1378 ALSHDGKVLATSSGVHSLASGTGHVQVA--RNALRLQVQ-----------DVP----AGD 1420
Query: 179 EQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
+ Y C A+N G S G + + V+ P L P A L L C L G P
Sbjct: 1421 DTYVCTAQNLLGSISTIGRLQVEGARVVAEP--GLDVPEGAA-----LNLSCRLLGGPGP 1473
Query: 238 I----LYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
+ WF++ D L + P+ +F + +G Y C A GA S V L
Sbjct: 1474 VGNSTFAWFWN-DRRLHAEPVPT---LAFT-HVARAQAGMYHCLAELPTGAAASAPVML 1527
Score = 42.7 bits (99), Expect = 5e-04
Identities = 65/267 (24%), Positives = 104/267 (38%), Gaps = 29/267 (10%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
EG V LTC + + AQ + +++D G + + + + D SY C
Sbjct: 1099 EGQLVNLTCLV--WTTHPAQLTYTWYQD----GQQRLDAHSIPLPNVTVRDATSYRCGVG 1152
Query: 90 TMASKVLRSRRSQINVHRVPV-ADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWY 148
SR ++V P ++ + GGQ+ +++C+V L +
Sbjct: 1153 PPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLA-----LVLCTVDSRPPAQLALSH 1207
Query: 149 KGAVGLNLQSKTQRSL--TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
G + L S T S+ T E+ + D Y C A + G + + S+ +R+
Sbjct: 1208 AGRL---LASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANT---SLELRLEGV 1261
Query: 207 RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFN-LS 265
R IL AP A + + C P LY +YH R G AS + L
Sbjct: 1262 RVIL---APEAAVPEGAPITVTCADPAAHAPTLYTWYHN-----GRWLQEGPAASLSFLV 1313
Query: 266 LTEEHSGNYSCEANNGLGAQRSEAVTL 292
T H+G YSC+A + G + S L
Sbjct: 1314 ATRAHAGAYSCQAQDAQGTRSSRPAAL 1340
Score = 36.2 bits (82), Expect = 0.048
Identities = 36/123 (29%), Positives = 50/123 (40%), Gaps = 9/123 (7%)
Query: 17 AELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAM 76
A LI+ + EG VTL+C+ + DA+F + GPG S L + A
Sbjct: 510 AARLLISPAAEVVEGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSS----LLLPAA 565
Query: 77 WKEDTGSYWCEAQTMASKVLRSRRSQINV---HRVPVADVSLETQPPGGQVMEGDRLVLI 133
D GSY C A+ S S + + V R P L+ G G R +L+
Sbjct: 566 SSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAAGAGA--GRRGLLL 623
Query: 134 CSV 136
C V
Sbjct: 624 CRV 626
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 64.7 bits (156), Expect = 1e-10
Identities = 69/244 (28%), Positives = 103/244 (42%), Gaps = 24/244 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I K D G Y CE + A + + + ++ P LE + GD +
Sbjct: 6043 LEILNSTKRDAGQYSCEIENEAGRDVCG--ALVSTLEPPYFVTELEPL----EAAVGDSV 6096
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYCVAEN 187
L C VA GT +IT WYKG L + + T A V +D+ +Y C AEN
Sbjct: 6097 SLQCQVA-GTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAEN 6155
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G + S V ++ P + + V + L C L GS PI +Y + +
Sbjct: 6156 SIGTASSKTV-FRIQERQLPPSFARQLKDIEQTVGLPVTLTCR-LNGSAPIQVCWYRDGV 6213
Query: 248 TLGS----RSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARD 302
L +++ A+ + T+ HSG YSC A+N LG S A R +AR+
Sbjct: 6214 LLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSA-------RLTARE 6266
Query: 303 PLRS 306
P +S
Sbjct: 6267 PKKS 6270
Score = 56.6 bits (135), Expect = 3e-08
Identities = 65/278 (23%), Positives = 112/278 (40%), Gaps = 30/278 (10%)
Query: 32 SPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDTGSY 84
S V TC++ + + +F+D + + + L+I + D G++
Sbjct: 4124 SVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNF 4183
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C A + + V P S T+P V+ G V + S G+ +T
Sbjct: 4184 TCRATNSVGS--KDSSGALIVQEPP----SFVTKPGSKDVLPGSA-VCLKSTFQGSTPLT 4236
Query: 145 FLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITV 201
W+KG L T+ +L + E+ V+ SD+ Y C N +G V +
Sbjct: 4237 IRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSN-----VAGGVECSA 4291
Query: 202 RIPVSRPILMLRA--PRAQAAVEDVLELHCEALRGSPPI-LYWFYHE-DITLGSRSAPSG 257
+ V P + P D +L C+ + G+PPI + WF ++ +I S+ S
Sbjct: 4292 NLFVKEPATFVEKLEPSQLLKKGDATQLACK-VTGTPPIKITWFANDREIKESSKHRMSF 4350
Query: 258 GGASFNLSLTE---EHSGNYSCEANNGLGAQRSEAVTL 292
++ L LT+ E SG Y CEA N G+ ++ +
Sbjct: 4351 VESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI 4388
Score = 55.5 bits (132), Expect = 8e-08
Identities = 68/248 (27%), Positives = 102/248 (41%), Gaps = 21/248 (8%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + ED G Y C + + K S +QI + P LE +V GD
Sbjct: 7925 LEIPSSTVEDAGQYNCYIENASGK--DSCSAQILILEPPYFVKQLEPV----KVSVGDSA 7978
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCVAEN 187
L C +A GT +I WYKG L + + R+ A V +D+ +Y C AEN
Sbjct: 7979 SLQCQLA-GTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAEN 8037
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G S +TV+ P + Q V + C A+ GS PI +Y +
Sbjct: 8038 SVG-EVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGK 8095
Query: 248 TLGSRSAPS------GGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVTLNFTGRRSA 300
L + +P+ A+ N+ T+ +G YSC A N +G+ S A + G+
Sbjct: 8096 PL--KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPP 8153
Query: 301 RDPLRSLP 308
+R P
Sbjct: 8154 FFDIRLAP 8161
Score = 52.8 bits (125), Expect = 5e-07
Identities = 72/283 (25%), Positives = 108/283 (38%), Gaps = 34/283 (12%)
Query: 29 TEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-------LQIAAMWKEDT 81
T G PVTLTC++ + A Q C++RD L + L+I +
Sbjct: 6187 TVGLPVTLTCRL----NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHS 6242
Query: 82 GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
G Y C A S R R P + +P V+ G+ C V G
Sbjct: 6243 GQYSCSASNPLGTASSSARLTA---REPKKSPFFDIKPVSIDVIAGESADFECHVT-GAQ 6298
Query: 142 DITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
+ W K + T T I V + D+ QY C A N G
Sbjct: 6299 PMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD-----M 6353
Query: 199 ITVRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPI-LYWF-----YHEDITLG 250
+ ++ V P ++ A + + ++L C+ + GSP I + WF HE
Sbjct: 6354 CSAQLSVKEPPKFVKKLEASKVAKQGESIQLECK-ISGSPEIKVSWFRNDSELHESWKYN 6412
Query: 251 SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
S + N + E+ SG+Y CEA+NG+G A S A+T+
Sbjct: 6413 MSFINSVALLTINEASAED-SGDYICEAHNGVGDASCSTALTV 6454
Score = 52.4 bits (124), Expect = 6e-07
Identities = 67/302 (22%), Positives = 110/302 (36%), Gaps = 37/302 (12%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGW-------SSSPKLQIAAMWKEDTG 82
+G + L CK+ S + + +FR+ L W +S L I ED+G
Sbjct: 6378 QGESIQLECKI----SGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSG 6433
Query: 83 SYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGD 142
Y CEA S + + V PV +P ++G ++L C ++ GT
Sbjct: 6434 DYICEAHNGVGDA--SCSTALTVKAPPV----FTQKPSPVGALKGSDVILQCEIS-GTPP 6486
Query: 143 ITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSI 199
+W K + K T + I ++ SD +Y+C A N G S + S+
Sbjct: 6487 FEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVG-SDTCSCSV 6545
Query: 200 TVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITL----GSRSAP 255
+ P P + + + D +EL P + W + +R +
Sbjct: 6546 KFKEP---PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF 6602
Query: 256 SGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSLPSPLPQE 314
A+ L E +SG Y C+ N G + AV + +P R + P P
Sbjct: 6603 IDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVL-------TVLEPARIIEKPEPMT 6655
Query: 315 FT 316
T
Sbjct: 6656 VT 6657
Score = 51.6 bits (122), Expect = 1e-06
Identities = 64/292 (21%), Positives = 113/292 (38%), Gaps = 44/292 (15%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSS 67
EPA + A P T G TL CK+ + + +++D + L ++
Sbjct: 5702 EPAVIVEKAGPMTVTVGETCTLECKV----AGTPELSVEWYKDGKLLTSSQKHKFSFYNK 5757
Query: 68 SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG 127
L+I ++ ++D G+Y + Q K + ++ VP + + GG + G
Sbjct: 5758 ISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVP-PSFTRRLKNTGGVL--G 5814
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYCV 184
+L C VA G+ I+ W+ + +K Q + + ++ S+ SD Y CV
Sbjct: 5815 ASCILECKVA-GSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCV 5873
Query: 185 AENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWFY 243
A N G V + V P ++ P + +RG+PP + WF
Sbjct: 5874 AANVAGSDECRAV-----LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWF- 5927
Query: 244 HEDITLGSRSAPSGGGAS------------FNLSLTEEHSGNYSCEANNGLG 283
G+R G + FN+ +++ SG Y+C +N G
Sbjct: 5928 -----RGARELVKGDRCNIYFEDTVAELELFNIDISQ--SGEYTCVVSNNAG 5972
Score = 51.2 bits (121), Expect = 1e-06
Identities = 67/264 (25%), Positives = 111/264 (42%), Gaps = 43/264 (16%)
Query: 50 FQFCFFRDTRALGPGWSSS-------PKLQIAAMWKEDTGSYWCEAQTMASKV-----LR 97
F+ +F+ +R L PG S + +L++ + ++G Y C A L
Sbjct: 6863 FKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 6922
Query: 98 SRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ 157
+ V R+ AD S+ET P +++ + GT I+ W K ++
Sbjct: 6923 VKEPATFVKRL--ADFSVETGSP----------IVLEATYTGTPPISVSWIKDEYLISQS 6970
Query: 158 SKTQRSLTAEYEIPSVRESDAE---QYYCVAENGYGPSP-SGLVSITVRIPVSRPILMLR 213
+ ++T + I + ES E QY C+ EN G LVS+ + P +
Sbjct: 6971 ERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV-----LEPPYFIEP 7025
Query: 214 APRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPS------GGGASFNLSLT 267
+A + + L C+ + G+P I +Y E L RSAP+ AS ++
Sbjct: 7026 LEHVEAVIGEPATLQCK-VDGTPEIRISWYKEHTKL--RSAPAYKMQFKNNVASLVINKV 7082
Query: 268 EEHS-GNYSCEANNGLGAQRSEAV 290
+ G YSC+A+N +GA S AV
Sbjct: 7083 DHSDVGEYSCKADNSVGAVASSAV 7106
Score = 49.7 bits (117), Expect = 4e-06
Identities = 61/294 (20%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQ-- 72
EPA++ A TE P+TL C + + + + + +D + + P S +
Sbjct: 5139 EPAQIVEKAKSVDVTEKDPMTLECVV----AGTPELKVKWLKDGKQIVPSRYFSMSFENN 5194
Query: 73 -----IAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG 127
I ++ K+D+G Y + + ++ +P + T+ + G
Sbjct: 5195 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKM---DKVLG 5251
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCV 184
+ + C V+ G+ I+ W+K ++ +K + + E+ ++ D Y C
Sbjct: 5252 SSIHMECKVS-GSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCK 5310
Query: 185 AENGYGPSP-SGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
N G SG+ +TV+ P P +++ R QA + +E L+G+PP ++
Sbjct: 5311 VSNVAGDDACSGI--LTVKEP---PSFLVKPGRQQAIPDSTVEFKA-ILKGTPPFKIKWF 5364
Query: 244 HEDITLGSRS----APSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTL 292
+D+ L S G + NL S+ +G Y+C N +G+ + L
Sbjct: 5365 KDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL 5418
Score = 49.7 bits (117), Expect = 4e-06
Identities = 67/291 (23%), Positives = 102/291 (35%), Gaps = 57/291 (19%)
Query: 27 HPTEGSPVTLTCKMP-------------FLQSSDAQFQFCFFRDTRALGPGWSSSPKLQI 73
H T G PV C++ L DA Q F + L QI
Sbjct: 7126 HETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATL----------QI 7175
Query: 74 AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLI 133
+ G Y C A S + ++ H VP + +P + G+
Sbjct: 7176 LQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPF---FDLKPVSVDLALGESGTFK 7232
Query: 134 CSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAENGYG 190
C V GT I W K + + +L TA + V + DA QY C A N G
Sbjct: 7233 CHVT-GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAG 7291
Query: 191 PSPSGLVSITVRIPVSRPILMLRA--PRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
S + ++ V P ++ P ++ C+ + GSP I +Y ++
Sbjct: 7292 KD-----SCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECK-IGGSPEIKVLWYKDETE 7345
Query: 249 LGSRSAPSGGGASFNLS------------LTEEHSGNYSCEANNGLGAQRS 287
+ S F +S L+ E SG+Y+CEA+N G+ S
Sbjct: 7346 IQESS-------KFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASS 7389
Score = 48.1 bits (113), Expect = 1e-05
Identities = 71/296 (23%), Positives = 109/296 (36%), Gaps = 46/296 (15%)
Query: 15 EPAELFLIASPSH-PTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WS 66
EP PS+ G L CK+ Q +F++ + L +
Sbjct: 3735 EPPSFVKKVDPSYLMLPGESARLHCKL----KGSPVIQVTWFKNNKELSESNTVRMYFVN 3790
Query: 67 SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
S L I + ED+GSY CEA S ++I + P +LE ++
Sbjct: 3791 SEAILDITDVKVEDSGSYSCEAVNDVGS--DSCSTEIVIKEPPSFIKTLEP----ADIVR 3844
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK----TQRSLTAEYEIPSVRESDAEQYY 182
G +L C V+ GTG W+K + K +Q+SL EI S +D +Y
Sbjct: 3845 GTNALLQCEVS-GTGPFEISWFKDKKQIRSSKKYRLFSQKSLVC-LEIFSFNSADVGEYE 3902
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCE------ALRGSP 236
CV N G + L+ P V+D++ L + A+RGS
Sbjct: 3903 CVVANEVG-----------KCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSE 3951
Query: 237 PI-LYWFYHEDITLG----SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRS 287
PI + W +++ S +G + G Y+C A N G+Q S
Sbjct: 3952 PISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTS 4007
Score = 47.0 bits (110), Expect = 3e-05
Identities = 52/227 (22%), Positives = 97/227 (42%), Gaps = 17/227 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQ + + + G Y C+ + A ++ + ++V + ++ +P +V GD
Sbjct: 7550 LQFSRVEPANAGKYTCQIKNDAG--MQECFATLSV----LEPATIVEKPESIKVTTGDTC 7603
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAEN 187
L C+VA GT +++ W+K L +K + S + +I +V SD+ Y +N
Sbjct: 7604 TLECTVA-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQN 7662
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G S S+ V P + + + C+ GSPPI ++HE
Sbjct: 7663 PVGKD-SCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVY-GSPPISVSWFHEGN 7720
Query: 248 TLGS----RSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEA 289
+ S ++ + + +++ EE SG+Y+C A N G+ A
Sbjct: 7721 EISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSA 7767
Score = 46.6 bits (109), Expect = 4e-05
Identities = 56/231 (24%), Positives = 96/231 (41%), Gaps = 13/231 (5%)
Query: 67 SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
+S L + + K D+G Y C A K S +Q+N+ + + + E
Sbjct: 8206 NSAHLTVLKVDKGDSGQYTCYAVNEVGK--DSCTAQLNIKERLIPPSFTKRLSETVEETE 8263
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYC 183
G+ L VA G+ IT WYK + + S T ++ T ++ +DA Y C
Sbjct: 8264 GNSFKLEGRVA-GSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTC 8322
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWF 242
N G S SI ++ P P+ + + ++L C ++GS PI + W
Sbjct: 8323 KVSNDAG-SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCH-VQGSEPIRIQWL 8380
Query: 243 YH-EDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLGAQRSEA 289
+I R + S + L L + SG+Y C+A+N G+ +++
Sbjct: 8381 KAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKS 8431
Score = 46.2 bits (108), Expect = 5e-05
Identities = 62/232 (26%), Positives = 96/232 (41%), Gaps = 20/232 (8%)
Query: 67 SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME 126
S+ L++ + ED+G Y CEAQ A S S + V P + E +P +V++
Sbjct: 4353 STAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS--SIVIVKESPY--FTKEFKPI--EVLK 4406
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQYYC 183
++L+ VA GT W+K L K + + +I +DA +Y C
Sbjct: 4407 EYDVMLLAEVA-GTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQC 4465
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPI-LYWF 242
N G S + R+ + P ++ + +++ L+GS PI + W
Sbjct: 4466 RVTNEVGSS-----ICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWL 4520
Query: 243 YHED-ITLGS--RSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAV 290
D IT R AS LS E +H G Y C+A N G QR A+
Sbjct: 4521 KDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSAL 4572
Score = 46.2 bits (108), Expect = 5e-05
Identities = 73/295 (24%), Positives = 107/295 (36%), Gaps = 43/295 (14%)
Query: 11 APLC--EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG---- 64
APL EP P G+ VT T + F +F+ + L PG
Sbjct: 7767 APLTVREPPSFVQKPDPMDVLTGTNVTFTS----IVKGTPPFSVSWFKGSSELVPGDRCN 7822
Query: 65 ---WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVA---DVSLETQ 118
S +L++ + +G Y C A K + I V D S+E
Sbjct: 7823 VSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKG 7882
Query: 119 PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRE 175
P ++EG GT I+ W K + + + T +A EIPS
Sbjct: 7883 KP--LILEG--------TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTV 7932
Query: 176 SDAEQYYCVAENGYGPSPSGLVSITVRIPV-SRPILMLRAPRAQAAVEDVLELHCEALRG 234
DA QY C EN SG S + +I + P + + + +V D L C+ L G
Sbjct: 7933 EDAGQYNCYIENA-----SGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQ-LAG 7986
Query: 235 SPPILYWFYHEDITLGSRSA------PSGGGASFNLSLTEEHSGNYSCEANNGLG 283
+P I +Y D L + + FN + SG Y C+A N +G
Sbjct: 7987 TPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFN-QVDINDSGEYICKAENSVG 8040
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/229 (24%), Positives = 85/229 (37%), Gaps = 20/229 (8%)
Query: 72 QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
QI+ E++G+Y CEA+ A S ++ V P L+ +V++ +
Sbjct: 4920 QISGARVENSGTYVCEARNDAGTA--SCSIELKVKEPPTFIRELKPV----EVVKYSDVE 4973
Query: 132 LICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENG 188
L C V GT W K + K T R I SD +Y C+ N
Sbjct: 4974 LECEVT-GTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSN- 5031
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
G S + R+ + P ++ V + GSPPI + +D
Sbjct: 5032 ----EGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQI 5087
Query: 249 LGSRS----APSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTL 292
L + A+ + S+ HSG Y+C+A N G +R A L
Sbjct: 5088 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLL 5136
Score = 45.4 bits (106), Expect = 8e-05
Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 19/188 (10%)
Query: 112 DVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYE-- 169
DV + + QV+E R V+ V D+ WYK + +N Q + + E
Sbjct: 3146 DVRIRSIKKEVQVIEKQRAVVEFEV--NEDDVDAHWYKDGIEINFQVQERHKYVVERRIH 3203
Query: 170 ---IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE 226
I R+SDA +Y VA S+T+ + P +L+ +
Sbjct: 3204 RMFISETRQSDAGEYTFVAGRNRS-------SVTLYVNAPEPPQVLQELQPVTVQSGKPA 3256
Query: 227 LHCEALRGSP-PILYWFYHED-ITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNG 281
C + G P P + W+ E ++ G + G + L L E E + Y+CEA N
Sbjct: 3257 RFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKND 3316
Query: 282 LGAQRSEA 289
G + A
Sbjct: 3317 YGVATTSA 3324
Score = 45.1 bits (105), Expect = 1e-04
Identities = 70/271 (25%), Positives = 104/271 (38%), Gaps = 34/271 (12%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDTGS 83
GS + + CK+ AQ+ F+D + + S L++ + EDT +
Sbjct: 5251 GSSIHMECKVSGSLPISAQW----FKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN 5306
Query: 84 YWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDI 143
Y C+ +A S + V P V PG Q D V ++ GT
Sbjct: 5307 YTCKVSNVAGDDACS--GILTVKEPPSFLVK-----PGRQQAIPDSTVEFKAILKGTPPF 5359
Query: 144 TFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSIT 200
W+K V L K L T+ + SV S QY C N G S T
Sbjct: 5360 KIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSD-----SCT 5414
Query: 201 VRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPI-LYWFYHEDITLGS---RSA 254
+ V+ P ++ A V+ D L C+ + GSP I + WF +E S R
Sbjct: 5415 TMLLVTEPPKFVKKLEASKIVKAGDSSRLECK-IAGSPEIRVVWFRNEHELPASDKYRMT 5473
Query: 255 PSGGGASFNLS-LTEEHSGNYSCEANNGLGA 284
A ++ L+ E SG++ CEA N G+
Sbjct: 5474 FIDSVAVIQMNNLSTEDSGDFICEAQNPAGS 5504
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/228 (24%), Positives = 84/228 (36%), Gaps = 17/228 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ-VMEGDR 129
LQ A + G Y C+ + + N+ + V + ++ + G V G+
Sbjct: 5668 LQFAKAEPANAGKYICQIKNDGGM-------RENMATLMVLEPAVIVEKAGPMTVTVGET 5720
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL---TAEYEIPSVRESDAEQYYCVAE 186
L C VA GT +++ WYK L K + S + I SV DA Y +
Sbjct: 5721 CTLECKVA-GTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQ 5779
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED 246
N G S V + V P R + L C+ SP + WF+ +
Sbjct: 5780 NNVGKSSCTAV-VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKT 5838
Query: 247 -ITLGSRSAPSGGGASFNL---SLTEEHSGNYSCEANNGLGAQRSEAV 290
I G++ + L SL GNY+C A N G+ AV
Sbjct: 5839 KIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 5886
Score = 44.3 bits (103), Expect = 2e-04
Identities = 66/289 (22%), Positives = 107/289 (37%), Gaps = 26/289 (8%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKM---PFLQSSDAQFQFCFFRDTRALGPGWSSSPKL 71
EPA + GSP+ L P + S + ++ + R S L
Sbjct: 6925 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTIL 6984
Query: 72 QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
+I ED Y C + A + + + ++V P LE + + G+
Sbjct: 6985 EILESTIEDYAQYSCLIENEAGQDICE--ALVSVLEPPYFIEPLEHV----EAVIGEPAT 7038
Query: 132 LICSVAMGTGDITFLWYK------GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
L C V GT +I WYK A +Q K A I V SD +Y C A
Sbjct: 7039 LQCKVD-GTPEIRISWYKEHTKLRSAPAYKMQFKNN---VASLVINKVDHSDVGEYSCKA 7094
Query: 186 ENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHE 245
+N G S V + ++ P + + + C + GS P+ +Y +
Sbjct: 7095 DNSVGAVASSAV-LVIKARKLPPFFARKLKDVHETLGFPVAFECR-INGSEPLQVSWYKD 7152
Query: 246 DITLGS----RSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEA 289
+ L +++ A+ + T++ H G Y+C A+N LG S A
Sbjct: 7153 GVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSA 7201
Score = 43.9 bits (102), Expect = 2e-04
Identities = 51/230 (22%), Positives = 91/230 (39%), Gaps = 20/230 (8%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
+Q+ + ED+G + CEAQ A S +++ V PV + PP + ++ +
Sbjct: 5481 IQMNNLSTEDSGDFICEAQNPAGST--SCSTKVIVKEPPV----FSSFPPIVETLKNAEV 5534
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C ++ GT +WYK L K ++ I +V SD +Y+C A+N
Sbjct: 5535 SLECELS-GTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 5593
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G S + + ++ ++ P P + + + EL P + W ++
Sbjct: 5594 EVG-SDTCVCTVKLKEP---PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649
Query: 248 TL----GSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTL 292
+ R A+ + E ++G Y C+ N G R TL
Sbjct: 5650 VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKND-GGMRENMATL 5698
Score = 43.5 bits (101), Expect = 3e-04
Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 21/130 (16%)
Query: 166 AEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP------VSRPILMLRAPRAQA 219
A EIP + D+ Y C A N G S S ++TVR P V LML A+
Sbjct: 3699 ATLEIPLAKLKDSGTYVCTASNEAGSS-SCSATVTVREPPSFVKKVDPSYLMLPGESAR- 3756
Query: 220 AVEDVLELHCEALRGSPPI-LYWFYH-EDITLGSRSAPSGGGASFNLSLTE---EHSGNY 274
LHC+ L+GSP I + WF + ++++ + + L +T+ E SG+Y
Sbjct: 3757 -------LHCK-LKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSY 3808
Query: 275 SCEANNGLGA 284
SCEA N +G+
Sbjct: 3809 SCEAVNDVGS 3818
Score = 42.4 bits (98), Expect = 7e-04
Identities = 79/338 (23%), Positives = 117/338 (34%), Gaps = 57/338 (16%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSS 67
EPA + P T G+P L C + A+ +F+D R L +
Sbjct: 6643 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAK----WFKDGRELSADSKHHITFINK 6698
Query: 68 SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG------ 121
L+I D G Y E + K ++VH VS PP
Sbjct: 6699 VASLKIPCAEMSDKGLYSFEVKNSVGK----SNCTVSVH------VSDRIVPPSFIRKLK 6748
Query: 122 -GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESD 177
+ G +VL C V+ G+ I+ W++ + K Q S + + + SD
Sbjct: 6749 DVNAILGASVVLECRVS-GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSD 6807
Query: 178 AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
Y CVA N G V + V P + P + + + +RG+PP
Sbjct: 6808 TGIYTCVAANVAGSDECSAV-----LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPP 6862
Query: 238 I-LYWFYHEDITLGSRSAPSGGGASFNLS--LTE--------EHSGNYSCEANNGLGAQR 286
+ WF GSR G + +L +TE SG+YSC N G+
Sbjct: 6863 FKVKWF------KGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSAS 6916
Query: 287 SEA---VTLNFTGRRSARDPLRSLPSPLPQEFTYLNSP 321
V T + D SP+ E TY +P
Sbjct: 6917 CTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTP 6954
Score = 42.0 bits (97), Expect = 9e-04
Identities = 52/215 (24%), Positives = 84/215 (39%), Gaps = 19/215 (8%)
Query: 79 EDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAM 138
ED+G Y CEA A S + + V P+ +P + ++G + L C +
Sbjct: 7371 EDSGDYTCEAHNAAGSA--SSSTSLKVKEPPI----FRKKPHPIETLKGADVHLECEL-Q 7423
Query: 139 GTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
GT WYK L K + I +V +D +Y C A N G S +
Sbjct: 7424 GTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVG-SDTC 7482
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHE-DITLGSRS- 253
+ SI ++ P P + + V ++L P + WF + +I S +
Sbjct: 7483 VGSIALKAP---PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNI 7539
Query: 254 --APSGGGASFNLSLTE-EHSGNYSCEANNGLGAQ 285
+ S A+ S E ++G Y+C+ N G Q
Sbjct: 7540 WISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQ 7574
Score = 40.4 bits (93), Expect = 0.003
Identities = 50/213 (23%), Positives = 88/213 (41%), Gaps = 19/213 (8%)
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSVRESDAEQ 180
V +GD L + GT +IT W+K L L SK + S+T + +I S + D+ +
Sbjct: 4590 VTQGDPATLQVKFS-GTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGE 4648
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILY 240
Y +N G S S I V + P + + + ++L C P +
Sbjct: 4649 YTFEVQNDVGRS-SCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 4707
Query: 241 WFY-HEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLGAQRSEAVTLNFTG 296
WF ++I+ + S + L +++ SG Y+C A N G + +G
Sbjct: 4708 WFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQC-------SG 4760
Query: 297 RRSARDPLRSLPSPLPQEFTYLNSPTPGQLQPI 329
+ ++P + P Q+ +N T QL+ +
Sbjct: 4761 HLTVKEPPYFVEKPQSQD---VNPNTRVQLKAL 4790
Score = 36.2 bits (82), Expect = 0.048
Identities = 57/294 (19%), Positives = 107/294 (36%), Gaps = 47/294 (15%)
Query: 29 TEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPG-------WSSSPKLQIAAMWKEDT 81
+EG P C++ S + ++ + + P + + +L+IA + ED
Sbjct: 3357 SEGQPARFQCRV-----SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDE 3411
Query: 82 GSYWCEAQTMASKV-------LRSRRSQINVHRVPVADVSLETQPPGGQVME------GD 128
G+Y A +V L + S ++ ++ ++ P + +E G
Sbjct: 3412 GTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGH 3471
Query: 129 RLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQ---RSLTAEYEIPSVRESDAEQYYCVA 185
C + ++ F W+K + K + EI + D +Y C A
Sbjct: 3472 LAKFTCEI-QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKA 3530
Query: 186 ENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH 244
N YG S + +++T P P + R V + C P++ +
Sbjct: 3531 SNEYGSVSCTATLTVTEAYP---PTFLSRPKSLTTFVGKAAKFICTVT--GTPVIETIWQ 3585
Query: 245 EDITLGSRSAPSGGGASFNL---------SLTEEHSGNYSCEANNGLGAQRSEA 289
+D G+ +PS + +LT + G YSC+A+N GA +A
Sbjct: 3586 KD---GAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQA 3636
Score = 35.0 bits (79), Expect = 0.11
Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 11/125 (8%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM-----EGDRLVL 132
K+D A+ +RS++ ++V +V VA S+E P GQ+M EG +
Sbjct: 31531 KKDLNMVVSAARISCGGAIRSQKG-VSVAKVKVA--SIEIGPVSGQIMHAVGEEGGHVKY 31587
Query: 133 ICSVAMGTGDITFLWYKGAVGLNLQSK---TQRSLTAEYEIPSVRESDAEQYYCVAENGY 189
+C + WY G L K T A + + + D Y C N Y
Sbjct: 31588 VCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDY 31647
Query: 190 GPSPS 194
G S
Sbjct: 31648 GEDSS 31652
Score = 32.3 bits (72), Expect = 0.69
Identities = 66/317 (20%), Positives = 107/317 (33%), Gaps = 50/317 (15%)
Query: 7 LLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS 66
L + AP EP ++ P G P + S Q + ++++ + L G+
Sbjct: 3231 LYVNAP--EPPQVLQELQPVTVQSGKPARFCAVI----SGRPQPKISWYKEEQLLSTGFK 3284
Query: 67 -------SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
L + + ED Y CEA+ S + V V D + P
Sbjct: 3285 CKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP 3344
Query: 120 PG-------GQVMEGDRLVLICSVAMGTGDITFLWY---KGAVGLNLQSKTQRSLTAEYE 169
P EG C V+ GT D+ WY K TQ T + E
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVS-GT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLE 3402
Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS----------------RPILMLR 213
I D Y VA N G S ++++ P S P++ +
Sbjct: 3403 IAEAYPEDEGTYTFVASNAVG-QVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRK 3461
Query: 214 APRAQAAVEDVLELHCEALRGSPPILY-WF-----YHEDITLGSRSAPSGGGASFNLSLT 267
+ A+ + + CE ++ +P + + WF +E RS+ L
Sbjct: 3462 IEPLEVALGHLAKFTCE-IQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI-LRTQ 3519
Query: 268 EEHSGNYSCEANNGLGA 284
G Y+C+A+N G+
Sbjct: 3520 VVDCGEYTCKASNEYGS 3536
Score = 32.0 bits (71), Expect = 0.90
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 7/132 (5%)
Query: 166 AEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVL 225
A+ IP+V ++++ +Y A NG G + S + V+ + P + R +
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATS-TAELLVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 226 ELHCEALRGSPPILYWFYHEDITLGSR--SAPSGGGASFNLSLTE---EHSGNYSCEANN 280
L + G P + FY + + S S G ++L + E E SG YS A N
Sbjct: 122 RLQVR-VTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180
Query: 281 GLGAQRSEAVTL 292
+G S A L
Sbjct: 181 SVGRATSTAELL 192
Score = 30.4 bits (67), Expect = 2.6
Identities = 41/163 (25%), Positives = 61/163 (37%), Gaps = 24/163 (14%)
Query: 8 LICAPLCEPAELFLIASPSHPTEGSPVTL----TCKMPFLQSSDAQFQFCFFRDTRALGP 63
L+C P A+L +I P+ VTL TC M Q S + +FR+ R L P
Sbjct: 8729 LVCGPHIASAKLTVI-EPAWERHLQDVTLKEGQTCTMT-CQFSVPNVKSEWFRNGRILKP 8786
Query: 64 GWSSSP-------KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLE 116
KL IA + ED G Y C+ + + + +++ + P +
Sbjct: 8787 QGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETS------AELRIEAEP---IQFT 8837
Query: 117 TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSK 159
+ V E C V+ +T WYKG L K
Sbjct: 8838 KRIQNIVVSEHQSATFECEVSFDDAIVT--WYKGPTELTESQK 8878
Score = 30.0 bits (66), Expect = 3.4
Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 18/146 (12%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLE--------- 116
S + L++ + K D+G Y C+A +A + +S++ + P + +
Sbjct: 8398 SGTAVLELRDVAKADSGDYVCKASNVAGS--DTTKSKVTIKDKPAVAPATKKAAVDGRLF 8455
Query: 117 --TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGA-VGLNLQSKT---QRSLTAEYEI 170
++P +V+E I V G W KG LN + Q+ A+ EI
Sbjct: 8456 FVSEPQSIRVVEKTTATFIAKVG-GDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 8514
Query: 171 PSVRESDAEQYYCVAENGYGPSPSGL 196
++D+ Y CVA N +G S +
Sbjct: 8515 RDTTKTDSGLYRCVAFNEHGEIESNV 8540
Score = 28.9 bits (63), Expect = 7.6
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 117 TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLT---AEYEIPSV 173
T+P V EG+ C G T W + L+ ++ Q + T + +EI SV
Sbjct: 32565 TKPRSMTVYEGESARFSCDTD-GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSV 32623
Query: 174 RESDAEQYYCVAENGYG 190
+ SD Y V EN G
Sbjct: 32624 QASDEGNYSVVVENSEG 32640
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 64.7 bits (156), Expect = 1e-10
Identities = 70/260 (26%), Positives = 106/260 (40%), Gaps = 25/260 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+IA ED G+Y C A+ A + R + V V +E P EG
Sbjct: 2810 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 2863
Query: 130 LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
L C A G+ + W K G + K + E + ++ DA Y C AEN
Sbjct: 2864 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 2922
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
G + + + +PV + R+ R + D L L C A RGSP P + W ++
Sbjct: 2923 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 2977
Query: 248 TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSL 307
S GG +++ E SG Y C A N +G R++AV+ ++
Sbjct: 2978 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVSFVH---------VKEA 3026
Query: 308 PSPLPQEFTYLNSPTPGQLQ 327
P + F+YL P G +Q
Sbjct: 3027 PVLQGEAFSYLVEPVGGSIQ 3046
Score = 58.5 bits (140), Expect = 9e-09
Identities = 64/231 (27%), Positives = 90/231 (38%), Gaps = 25/231 (10%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P LQ+ A+ D+G+Y C A + A + R Q+ V P + S QP
Sbjct: 2257 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 2312
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
+ G + L+C A GT W+K L R+ +R DA
Sbjct: 2313 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 2365
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
Y C+AE SP+G + + R+ V P I+ R PR L L C P
Sbjct: 2366 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 2420
Query: 238 ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGA 284
+ W H D + A P G +L+ SG+YSC A N G+
Sbjct: 2421 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGS 2469
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)
Query: 82 GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
G+Y CE + S+ Q+ VH P ++ +PP + D + + A G
Sbjct: 1040 GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 1095
Query: 142 DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
T W + +GL LQ++ Q + + + +Y CVAEN G +
Sbjct: 1096 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 1150
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
++V +P + AA+ L L CEA+ PP + WF E+ ++ G +
Sbjct: 1151 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 1209
Query: 255 PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
GG ++ T+E SG YSC A+N G R
Sbjct: 1210 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 1242
Score = 53.1 bits (126), Expect = 4e-07
Identities = 61/236 (25%), Positives = 90/236 (38%), Gaps = 25/236 (10%)
Query: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
+S P LQI + D G Y C A +A + R ++ V ++E P V
Sbjct: 653 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 706
Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
+E + L C +A G W+KG ++ S+ I + SDA Y C
Sbjct: 707 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 765
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
VA N G + + +R+ V I + + V + L C A P L W
Sbjct: 766 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 822
Query: 244 HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAV 290
G+ +P+G GG L S SG YSC A + +G R + V
Sbjct: 823 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 873
Score = 52.8 bits (125), Expect = 5e-07
Identities = 55/223 (24%), Positives = 83/223 (37%), Gaps = 17/223 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
LQ AA+ +ED+G+Y C A+ + S ++V PV S +P GG +
Sbjct: 2991 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 3046
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C V G W K + L + I DA +Y C+AEN
Sbjct: 3047 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 3101
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G + + + + S P+ + D + L C+A P + W
Sbjct: 3102 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 3157
Query: 248 TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEA 289
SR + S L E +G Y C A+N LG+ + A
Sbjct: 3158 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARA 3200
Score = 52.0 bits (123), Expect = 8e-07
Identities = 70/267 (26%), Positives = 102/267 (38%), Gaps = 32/267 (11%)
Query: 32 SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
+PV LTC P + S A Q A G G+ SP L+I G Y
Sbjct: 2681 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 2734
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C A+ A + + + V PV ++ P + + + ++L C A G T
Sbjct: 2735 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 2787
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
W K + + TQ + I DA Y C+A+N G S G + V++P
Sbjct: 2788 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 2846
Query: 205 VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
P++ P L C+A RGSP P + W G+ PSG
Sbjct: 2847 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 2902
Query: 260 ASFNLSLTEEHSGNYSCEANNGLGAQR 286
NL + +G Y+C A N +G R
Sbjct: 2903 LVKNLE--GQDAGTYTCTAENAVGRAR 2927
Score = 50.4 bits (119), Expect = 2e-06
Identities = 59/240 (24%), Positives = 91/240 (37%), Gaps = 35/240 (14%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV------ 124
LQI KED G Y C + ++ N H + S+ P G+V
Sbjct: 1406 LQILNAQKEDAGQYTCVVTNELGEAVK------NYHVEVLIPPSISKDDPLGEVGVKEVK 1459
Query: 125 -MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYY 182
L L C + T WYK + S+ Q +I + SD+ +Y
Sbjct: 1460 TKVNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL 1518
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE-------- 226
CVA N G + P+ + + ++ R A+ V + E
Sbjct: 1519 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY 1578
Query: 227 LHCEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
L+C+ PP L W Y ED ++ G + GG + L E++G YSC+A+N +G
Sbjct: 1579 LYCDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1637
Score = 47.8 bits (112), Expect = 2e-05
Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
+P EL L T G+P+ L C Q + +D +AL ++S ++
Sbjct: 2310 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 2358
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
+ D G Y C A++ A + +S R ++ V P G + + G +LV
Sbjct: 2359 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 2409
Query: 132 LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
L CSV A IT W++ + L + TQ + ++ ++ +D+ Y C A N
Sbjct: 2410 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 2466
Query: 190 GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G S+ R+ + P + P +V L C+A P++ W + +
Sbjct: 2467 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 2521
Query: 249 LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
L RS P G S + + + +G+Y C A+N G+ R
Sbjct: 2522 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 2562
Score = 45.4 bits (106), Expect = 8e-05
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+LQ+ D G Y C+A ++ R + V P +P + + G
Sbjct: 366 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 422
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
+ L C VA G T W+ GL + + L + + S E+ + Y CVA
Sbjct: 423 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 479
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
+ P+ ++ +V + V +L+ + V LEL C+A P + W +
Sbjct: 480 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 536
Query: 245 ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
E++ G + A G + ++ E +HSG ++C+A N G +E
Sbjct: 537 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 581
Score = 45.4 bits (106), Expect = 8e-05
Identities = 72/310 (23%), Positives = 107/310 (34%), Gaps = 32/310 (10%)
Query: 54 FFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRV 108
+++D++AL G + LQ+ D+G Y CEA A R Q V
Sbjct: 1780 WYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG------RDQKLVQLS 1833
Query: 109 PVADVSLETQPPGGQ----VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL 164
+ + P G Q V GD+ VL C + T WYK L L +TQ
Sbjct: 1834 VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETD-ALPEPTVTWYKDGQPLVLAQRTQALR 1892
Query: 165 TAE-YEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE- 222
+ EI + SD Y C N G + ++TV++P + P+ + +
Sbjct: 1893 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR-TFTLTVQVPPT-----FENPKTETVSQV 1946
Query: 223 --DVLELHCEALRGSPPILYWFYHEDITLGS--RSAPSGGGASFNLSLTEEHSGNYSCEA 278
L L C+ P + W S S GG L +G Y+C A
Sbjct: 1947 AGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 2006
Query: 279 NNGLGAQRSEAVTLNFTGRRSARDPLRSLPSPLPQEFTYLNSPTPGQLQP----IYENEP 334
N R + V R + L + L+ GQ P + + P
Sbjct: 2007 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSP 2066
Query: 335 REQSVAVHGR 344
Q + H R
Sbjct: 2067 LGQDMGPHLR 2076
Score = 43.1 bits (100), Expect = 4e-04
Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 12/173 (6%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQ+ A+ D+G Y C A+ A S ++ +H VP ++ + PP V
Sbjct: 2446 LQLQALSTADSGDYSCTARNAAGST--SVAFRVEIHTVP----TIRSGPPAVNVSVNQTA 2499
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGY 189
+L C A G W K V L+ +S L I V DA Y C+A N
Sbjct: 2500 LLPCQ-ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSA 2558
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWF 242
G G + P P L CEA P++ W+
Sbjct: 2559 GSDRQGRDLRVLEPPAIAP----SPSNLTLTAHTPALLPCEASGSPKPLVVWW 2607
Score = 41.2 bits (95), Expect = 0.001
Identities = 61/262 (23%), Positives = 97/262 (37%), Gaps = 18/262 (6%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
E +P L C + D ++R+ + L G S LQI + E+ G Y
Sbjct: 1573 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 1628
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C+A + ++ V PV E V + L C A+G T
Sbjct: 1629 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 1685
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
W + + + + Q + ++ + +DA Y CVAEN G S T+R+
Sbjct: 1686 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 1742
Query: 204 PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
V I L + A + + L C+ P + W+ + ++LG G +
Sbjct: 1743 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1802
Query: 263 NLSLTE-EHSGNYSCEANNGLG 283
L SG Y+CEA N G
Sbjct: 1803 QLGRARLSDSGMYTCEALNAAG 1824
Score = 37.7 bits (86), Expect = 0.016
Identities = 59/263 (22%), Positives = 113/263 (42%), Gaps = 20/263 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
GSP+ LTC + + + + + ++ A+ S +LQ++ + G+Y C A+
Sbjct: 1948 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 2007
Query: 90 TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
++ + + V R+ + V+ E V+EG + L C D+ +L
Sbjct: 2008 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 2062
Query: 148 YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
+G ++ + L + +R SDA Y CVA N G + L ++ V +P
Sbjct: 2063 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 2119
Query: 207 RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
P + A + V +++ + C +RGSPPI + + + L R+ G G +
Sbjct: 2120 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 2177
Query: 262 FNLSLTE-EHSGNYSCEANNGLG 283
+S + +G ++C A + G
Sbjct: 2178 LRISKVQLADAGIFTCVAASPAG 2200
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 64.7 bits (156), Expect = 1e-10
Identities = 70/260 (26%), Positives = 106/260 (40%), Gaps = 25/260 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+IA ED G+Y C A+ A + R + V V +E P EG
Sbjct: 4001 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 4054
Query: 130 LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
L C A G+ + W K G + K + E + ++ DA Y C AEN
Sbjct: 4055 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 4113
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
G + + + +PV + R+ R + D L L C A RGSP P + W ++
Sbjct: 4114 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 4168
Query: 248 TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSL 307
S GG +++ E SG Y C A N +G R++AV+ ++
Sbjct: 4169 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVSFVH---------VKEA 4217
Query: 308 PSPLPQEFTYLNSPTPGQLQ 327
P + F+YL P G +Q
Sbjct: 4218 PVLQGEAFSYLVEPVGGSIQ 4237
Score = 63.2 bits (152), Expect = 4e-10
Identities = 64/238 (26%), Positives = 92/238 (38%), Gaps = 20/238 (8%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P SSS KL+I A + D G+Y C A S Q+ V P T+ P
Sbjct: 740 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQL-----TELP 792
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKG-------AVGLNLQSKTQRSLTAEYEIPSV 173
+E R L+ A G T W +G +G S++++ + SV
Sbjct: 793 RDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESV 852
Query: 174 RESDAEQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
D Y C A N +G + +T P P + AP + + L C L
Sbjct: 853 APEDQAPYVCEARNVFGKVQAEARLIVTGHAP---PQIASSAPTVRVLEGQPVSLPCIVL 909
Query: 233 RGSP-PILYWFYH-EDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSE 288
G P P +W + GSR + G+ +EH+G YSC A N G+Q +
Sbjct: 910 AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRD 967
Score = 58.9 bits (141), Expect = 7e-09
Identities = 60/228 (26%), Positives = 91/228 (39%), Gaps = 23/228 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I + ED G+Y C+A + + + + + ++ VS V G+
Sbjct: 662 LIIQGVAPEDAGNYSCQA----TNEVGTDQETVTLYYTDPPSVSAVNAVV--LVAVGEEA 715
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
VL+C A G +WY+G GL + + S + + IP+ +E DA Y C A N G
Sbjct: 716 VLVCE-ASGVPPPRVIWYRG--GLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELG 772
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
+ S +++ V + PR + L C A PP + W + L
Sbjct: 773 DA-----SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL 827
Query: 250 G--------SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
G SRS G F S+ E Y CEA N G ++EA
Sbjct: 828 GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEA 875
Score = 58.5 bits (140), Expect = 9e-09
Identities = 64/231 (27%), Positives = 90/231 (38%), Gaps = 25/231 (10%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P LQ+ A+ D+G+Y C A + A + R Q+ V P + S QP
Sbjct: 3448 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 3503
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
+ G + L+C A GT W+K L R+ +R DA
Sbjct: 3504 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 3556
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
Y C+AE SP+G + + R+ V P I+ R PR L L C P
Sbjct: 3557 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 3611
Query: 238 ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGA 284
+ W H D + A P G +L+ SG+YSC A N G+
Sbjct: 3612 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGS 3660
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)
Query: 82 GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
G+Y CE + S+ Q+ VH P ++ +PP + D + + A G
Sbjct: 2231 GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 2286
Query: 142 DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
T W + +GL LQ++ Q + + + +Y CVAEN G +
Sbjct: 2287 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 2341
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
++V +P + AA+ L L CEA+ PP + WF E+ ++ G +
Sbjct: 2342 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 2400
Query: 255 PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
GG ++ T+E SG YSC A+N G R
Sbjct: 2401 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 2433
Score = 53.1 bits (126), Expect = 4e-07
Identities = 61/236 (25%), Positives = 90/236 (38%), Gaps = 25/236 (10%)
Query: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
+S P LQI + D G Y C A +A + R ++ V ++E P V
Sbjct: 1844 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 1897
Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
+E + L C +A G W+KG ++ S+ I + SDA Y C
Sbjct: 1898 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 1956
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
VA N G + + +R+ V I + + V + L C A P L W
Sbjct: 1957 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 2013
Query: 244 HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAV 290
G+ +P+G GG L S SG YSC A + +G R + V
Sbjct: 2014 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 2064
Score = 52.8 bits (125), Expect = 5e-07
Identities = 55/223 (24%), Positives = 83/223 (37%), Gaps = 17/223 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
LQ AA+ +ED+G+Y C A+ + S ++V PV S +P GG +
Sbjct: 4182 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 4237
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C V G W K + L + I DA +Y C+AEN
Sbjct: 4238 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 4292
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G + + + + S P+ + D + L C+A P + W
Sbjct: 4293 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 4348
Query: 248 TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEA 289
SR + S L E +G Y C A+N LG+ + A
Sbjct: 4349 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARA 4391
Score = 52.0 bits (123), Expect = 8e-07
Identities = 70/267 (26%), Positives = 102/267 (38%), Gaps = 32/267 (11%)
Query: 32 SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
+PV LTC P + S A Q A G G+ SP L+I G Y
Sbjct: 3872 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 3925
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C A+ A + + + V PV ++ P + + + ++L C A G T
Sbjct: 3926 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 3978
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
W K + + TQ + I DA Y C+A+N G S G + V++P
Sbjct: 3979 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 4037
Query: 205 VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
P++ P L C+A RGSP P + W G+ PSG
Sbjct: 4038 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 4093
Query: 260 ASFNLSLTEEHSGNYSCEANNGLGAQR 286
NL + +G Y+C A N +G R
Sbjct: 4094 LVKNLE--GQDAGTYTCTAENAVGRAR 4118
Score = 50.4 bits (119), Expect = 2e-06
Identities = 59/240 (24%), Positives = 91/240 (37%), Gaps = 35/240 (14%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV------ 124
LQI KED G Y C + ++ N H + S+ P G+V
Sbjct: 2597 LQILNAQKEDAGQYTCVVTNELGEAVK------NYHVEVLIPPSISKDDPLGEVGVKEVK 2650
Query: 125 -MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYY 182
L L C + T WYK + S+ Q +I + SD+ +Y
Sbjct: 2651 TKVNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYL 2709
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE-------- 226
CVA N G + P+ + + ++ R A+ V + E
Sbjct: 2710 CVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAY 2769
Query: 227 LHCEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
L+C+ PP L W Y ED ++ G + GG + L E++G YSC+A+N +G
Sbjct: 2770 LYCDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 2828
Score = 47.8 bits (112), Expect = 2e-05
Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
+P EL L T G+P+ L C Q + +D +AL ++S ++
Sbjct: 3501 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 3549
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
+ D G Y C A++ A + +S R ++ V P G + + G +LV
Sbjct: 3550 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 3600
Query: 132 LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
L CSV A IT W++ + L + TQ + ++ ++ +D+ Y C A N
Sbjct: 3601 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 3657
Query: 190 GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G S+ R+ + P + P +V L C+A P++ W + +
Sbjct: 3658 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 3712
Query: 249 LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
L RS P G S + + + +G+Y C A+N G+ R
Sbjct: 3713 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 3753
Score = 45.8 bits (107), Expect = 6e-05
Identities = 66/240 (27%), Positives = 94/240 (39%), Gaps = 39/240 (16%)
Query: 64 GWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ 123
G S L++A + D+G Y C A A S R + V P ++ P +
Sbjct: 1077 GLLPSGSLRLAQVQVGDSGHYECTASNPAGSA--SHRYVLGVQVPP----QVQPGPRVLK 1130
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
V+ G+ L L C VA G + W K V L R ++R SDA +Y C
Sbjct: 1131 VLVGEALDLNC-VAEGNPEPQLSWSKDGVVLQ-----GRGPQGSVHFAAIRTSDAGRYRC 1184
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVL----ELHCEALRGSP-PI 238
A N +G+ + V + V P A +E V L C A RG+P P
Sbjct: 1185 EASNS-----AGVDAWEVELRVLEPPHW-GADETSGLLERVAGENASLPCPA-RGTPKPQ 1237
Query: 239 LYWFYHEDITLGSRSAPSGG---------GASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
+ W G S P G G+ F S++ SG+Y C+A N +G+ A
Sbjct: 1238 VTW------RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRA 1291
Score = 45.4 bits (106), Expect = 8e-05
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+LQ+ D G Y C+A ++ R + V P +P + + G
Sbjct: 1557 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 1613
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
+ L C VA G T W+ GL + + L + + S E+ + Y CVA
Sbjct: 1614 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 1670
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
+ P+ ++ +V + V +L+ + V LEL C+A P + W +
Sbjct: 1671 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 1727
Query: 245 ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
E++ G + A G + ++ E +HSG ++C+A N G +E
Sbjct: 1728 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 1772
Score = 45.4 bits (106), Expect = 8e-05
Identities = 72/310 (23%), Positives = 107/310 (34%), Gaps = 32/310 (10%)
Query: 54 FFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRV 108
+++D++AL G + LQ+ D+G Y CEA A R Q V
Sbjct: 2971 WYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG------RDQKLVQLS 3024
Query: 109 PVADVSLETQPPGGQ----VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL 164
+ + P G Q V GD+ VL C + T WYK L L +TQ
Sbjct: 3025 VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETD-ALPEPTVTWYKDGQPLVLAQRTQALR 3083
Query: 165 TAE-YEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE- 222
+ EI + SD Y C N G + ++TV++P + P+ + +
Sbjct: 3084 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR-TFTLTVQVPPT-----FENPKTETVSQV 3137
Query: 223 --DVLELHCEALRGSPPILYWFYHEDITLGS--RSAPSGGGASFNLSLTEEHSGNYSCEA 278
L L C+ P + W S S GG L +G Y+C A
Sbjct: 3138 AGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 3197
Query: 279 NNGLGAQRSEAVTLNFTGRRSARDPLRSLPSPLPQEFTYLNSPTPGQLQP----IYENEP 334
N R + V R + L + L+ GQ P + + P
Sbjct: 3198 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSP 3257
Query: 335 REQSVAVHGR 344
Q + H R
Sbjct: 3258 LGQDMGPHLR 3267
Score = 43.1 bits (100), Expect = 4e-04
Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 12/173 (6%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQ+ A+ D+G Y C A+ A S ++ +H VP ++ + PP V
Sbjct: 3637 LQLQALSTADSGDYSCTARNAAGST--SVAFRVEIHTVP----TIRSGPPAVNVSVNQTA 3690
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGY 189
+L C A G W K V L+ +S L I V DA Y C+A N
Sbjct: 3691 LLPCQ-ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSA 3749
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWF 242
G G + P P L CEA P++ W+
Sbjct: 3750 GSDRQGRDLRVLEPPAIAP----SPSNLTLTAHTPALLPCEASGSPKPLVVWW 3798
Score = 42.4 bits (98), Expect = 7e-04
Identities = 61/263 (23%), Positives = 96/263 (36%), Gaps = 21/263 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYW 85
G L+C++ +A + + RD R L + L+I+ + D G Y
Sbjct: 531 GETAVLSCRV----LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 586
Query: 86 CEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITF 145
C A A+ V R+ + V P + +Q +G + + CS A G
Sbjct: 587 CVASN-ANGVTRAS-VWLLVREAPQVSIHTSSQ----HFSQGVEVKVSCS-ASGYPTPHI 639
Query: 146 LWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPV 205
W + + L S+ I V DA Y C A N G ++T+
Sbjct: 640 SWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQE---TVTLYYTD 696
Query: 206 SRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS 265
+ + A A E+ + L CEA PP + W Y + + S G +
Sbjct: 697 PPSVSAVNAVVLVAVGEEAV-LVCEASGVPPPRVIW-YRGGLEMILAPEGSSSGKLRIPA 754
Query: 266 LTEEHSGNYSCEANNGLGAQRSE 288
E +G Y+C A N LG +E
Sbjct: 755 AQERDAGTYTCRAVNELGDASAE 777
Score = 41.2 bits (95), Expect = 0.001
Identities = 61/262 (23%), Positives = 97/262 (37%), Gaps = 18/262 (6%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
E +P L C + D ++R+ + L G S LQI + E+ G Y
Sbjct: 2764 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 2819
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C+A + ++ V PV E V + L C A+G T
Sbjct: 2820 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 2876
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
W + + + + Q + ++ + +DA Y CVAEN G S T+R+
Sbjct: 2877 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 2933
Query: 204 PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
V I L + A + + L C+ P + W+ + ++LG G +
Sbjct: 2934 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 2993
Query: 263 NLSLTE-EHSGNYSCEANNGLG 283
L SG Y+CEA N G
Sbjct: 2994 QLGRARLSDSGMYTCEALNAAG 3015
Score = 37.7 bits (86), Expect = 0.016
Identities = 59/263 (22%), Positives = 113/263 (42%), Gaps = 20/263 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
GSP+ LTC + + + + + ++ A+ S +LQ++ + G+Y C A+
Sbjct: 3139 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 3198
Query: 90 TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
++ + + V R+ + V+ E V+EG + L C D+ +L
Sbjct: 3199 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 3253
Query: 148 YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
+G ++ + L + +R SDA Y CVA N G + L ++ V +P
Sbjct: 3254 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 3310
Query: 207 RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
P + A + V +++ + C +RGSPPI + + + L R+ G G +
Sbjct: 3311 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 3368
Query: 262 FNLSLTE-EHSGNYSCEANNGLG 283
+S + +G ++C A + G
Sbjct: 3369 LRISKVQLADAGIFTCVAASPAG 3391
Score = 28.9 bits (63), Expect = 7.6
Identities = 61/238 (25%), Positives = 85/238 (35%), Gaps = 34/238 (14%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L +A++ D+G Y C+A SRR+++ V+ P + + + M G L
Sbjct: 1263 LFLASVSPADSGDYECQATNEVGST--SRRAKLVVYVPP--SIREDGRKANVSGMAGQSL 1318
Query: 131 VLICSVAMGTGDITFLWYKGA--VGLNL------------QSKTQRSLTAEYEI--PSVR 174
L C A G +W K A VG+ L Q R L + P ++
Sbjct: 1319 TLECD-ANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQ 1377
Query: 175 ESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQ----AAVEDVLELHCE 230
E D+ Y C AEN +G + V P +L A AQ A DV EL C
Sbjct: 1378 EGDSGLYSCRAEN-----QAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADV-ELQCW 1431
Query: 231 ALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH---SGNYSCEANNGLGAQ 285
P + W L L +T H G Y C A + G Q
Sbjct: 1432 TSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 1489
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 64.7 bits (156), Expect = 1e-10
Identities = 70/260 (26%), Positives = 106/260 (40%), Gaps = 25/260 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+L+IA ED G+Y C A+ A + R + V V +E P EG
Sbjct: 2719 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPV------IENGLPDLSTTEGSH 2772
Query: 130 LVLICSVAMGTGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENG 188
L C A G+ + W K G + K + E + ++ DA Y C AEN
Sbjct: 2773 AFLPCK-ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENA 2831
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDI 247
G + + + +PV + R+ R + D L L C A RGSP P + W ++
Sbjct: 2832 VGRARRRVHLTILVLPVFTTLPGDRSLR----LGDRLWLRCAA-RGSPTPRIGWTVNDRP 2886
Query: 248 TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSL 307
S GG +++ E SG Y C A N +G R++AV+ ++
Sbjct: 2887 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG--RTQAVSFVH---------VKEA 2935
Query: 308 PSPLPQEFTYLNSPTPGQLQ 327
P + F+YL P G +Q
Sbjct: 2936 PVLQGEAFSYLVEPVGGSIQ 2955
Score = 58.5 bits (140), Expect = 9e-09
Identities = 64/231 (27%), Positives = 90/231 (38%), Gaps = 25/231 (10%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P LQ+ A+ D+G+Y C A + A + R Q+ V P + S QP
Sbjct: 2166 LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEA--RRHFQLTVMEPPHIEDS--GQPT 2221
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ 180
+ G + L+C A GT W+K L R+ +R DA
Sbjct: 2222 ELSLTPGAPMELLCD-AQGTPQPNITWHKDGQALTRLENNSRATRV------LRVRDAGL 2274
Query: 181 YYCVAENGYGPSPSGLVSITVRIPVSRP--ILMLRAPR-AQAAVEDVLELHCEALRGSPP 237
Y C+AE SP+G + + R+ V P I+ R PR L L C P
Sbjct: 2275 YTCLAE-----SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAP 2329
Query: 238 ILYWFYHEDITLGSRSA----PSGGGASFNLSLTEEHSGNYSCEANNGLGA 284
+ W H D + A P G +L+ SG+YSC A N G+
Sbjct: 2330 KITW--HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGS 2378
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 18/213 (8%)
Query: 82 GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTG 141
G+Y CE + S+ Q+ VH P ++ +PP + D + + A G
Sbjct: 949 GTYTCECSNVVGN--SSQDLQLEVHVPP--QIAGPREPPTQVSVVQDGVATLECNATGKP 1004
Query: 142 DITFLWYKGA------VGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSG 195
T W + +GL LQ++ Q + + + +Y CVAEN G +
Sbjct: 1005 PPTVTWERDGQPVGAELGLQLQNQGQ-----SLHVERAQAAHTGRYSCVAENLAGRAERK 1059
Query: 196 LVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-ITLGSRSA 254
++V +P + AA+ L L CEA+ PP + WF E+ ++ G +
Sbjct: 1060 F-ELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTY 1118
Query: 255 PSGGGASFNLSLTEEH-SGNYSCEANNGLGAQR 286
GG ++ T+E SG YSC A+N G R
Sbjct: 1119 LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEAR 1151
Score = 53.1 bits (126), Expect = 4e-07
Identities = 61/236 (25%), Positives = 90/236 (38%), Gaps = 25/236 (10%)
Query: 65 WSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
+S P LQI + D G Y C A +A + R ++ V ++E P V
Sbjct: 562 YSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLV------PPNIEPGPVNKAV 615
Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYC 183
+E + L C +A G W+KG ++ S+ I + SDA Y C
Sbjct: 616 LENASVTLEC-LASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 674
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
VA N G + + +R+ V I + + V + L C A P L W
Sbjct: 675 VASNVAGSTE---LRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLK 731
Query: 244 HEDITLGSRSAPSG--------GGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAV 290
G+ +P+G GG L S SG YSC A + +G R + V
Sbjct: 732 D-----GNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 782
Score = 52.8 bits (125), Expect = 5e-07
Identities = 55/223 (24%), Positives = 83/223 (37%), Gaps = 17/223 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD---VSLETQPPGGQVMEG 127
LQ AA+ +ED+G+Y C A+ + S ++V PV S +P GG +
Sbjct: 2900 LQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQ-- 2955
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C V G W K + L + I DA +Y C+AEN
Sbjct: 2956 ----LDC-VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAEN 3010
Query: 188 GYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
G + + + + S P+ + D + L C+A P + W
Sbjct: 3011 EMGVAK----KVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQP 3066
Query: 248 TLGSRSAPSGGGASFNLSLTEE-HSGNYSCEANNGLGAQRSEA 289
SR + S L E +G Y C A+N LG+ + A
Sbjct: 3067 LRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARA 3109
Score = 52.0 bits (123), Expect = 8e-07
Identities = 70/267 (26%), Positives = 102/267 (38%), Gaps = 32/267 (11%)
Query: 32 SPVTLTCKM-----PFLQSSDAQFQFCFFRDTRALGPGWSSSPK--LQIAAMWKEDTGSY 84
+PV LTC P + S A Q A G G+ SP L+I G Y
Sbjct: 2590 APVVLTCHSTGIPAPTVSWSKAGAQL------GARGSGYRVSPSGALEIGQALPIHAGRY 2643
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C A+ A + + + V PV ++ P + + + ++L C A G T
Sbjct: 2644 TCSARNSAG--VAHKHVFLTVQASPV----VKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 2696
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIP 204
W K + + TQ + I DA Y C+A+N G S G + V++P
Sbjct: 2697 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG-SAMGKTRLVVQVP 2755
Query: 205 VSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRS----APSGGG 259
P++ P L C+A RGSP P + W G+ PSG
Sbjct: 2756 ---PVIENGLPDLSTTEGSHAFLPCKA-RGSPEPNITWDKDGQPVSGAEGKFTIQPSGEL 2811
Query: 260 ASFNLSLTEEHSGNYSCEANNGLGAQR 286
NL + +G Y+C A N +G R
Sbjct: 2812 LVKNLE--GQDAGTYTCTAENAVGRAR 2836
Score = 49.3 bits (116), Expect = 5e-06
Identities = 66/268 (24%), Positives = 106/268 (39%), Gaps = 23/268 (8%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS--SPK---LQIAAMWKEDTGSY 84
+G L C + + Q + +F+D R L G + SP LQ+ G Y
Sbjct: 1177 DGQTAHLMCNV----TGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHY 1232
Query: 85 WCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLIC-SVAMGTGD 142
C A + +++ Q++V P + + ++ V + + LIC ++A + +
Sbjct: 1233 SCIAANAVGE--KTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPN 1290
Query: 143 ITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITV 201
IT W K Q T +I + ++ DA QY CV N G + + V
Sbjct: 1291 IT--WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNY-HVEV 1347
Query: 202 RIPVS----RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH-EDITLGSRSAPS 256
IP S P+ + + V L L CE+ PP + W+ + +T SR
Sbjct: 1348 LIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVL 1407
Query: 257 GGGASFNLSLTE-EHSGNYSCEANNGLG 283
G G + T+ SG Y C A N G
Sbjct: 1408 GEGRLLQIQPTQVSDSGRYLCVATNVAG 1435
Score = 48.9 bits (115), Expect = 7e-06
Identities = 56/238 (23%), Positives = 94/238 (39%), Gaps = 31/238 (13%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRV-----PVADVSLETQPPGGQVM 125
LQI KED G Y C + +++ ++ + P+A+V ++ +
Sbjct: 1315 LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEV----KTK 1370
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCV 184
L L C + T WYK + S+ Q +I + SD+ +Y CV
Sbjct: 1371 VNSTLTLECE-SWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCV 1429
Query: 185 AENGYGPSPSGLVSITVRIPVSRPI--------LMLRAPRAQAAVEDVLE--------LH 228
A N G + P+ + + ++ R A+ V + E L+
Sbjct: 1430 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1489
Query: 229 CEALRGSPPILYWFYHED--ITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
C+ PP L W Y ED ++ G + GG + L E++G YSC+A+N +G
Sbjct: 1490 CDTNAIPPPDLTW-YREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVG 1546
Score = 47.8 bits (112), Expect = 2e-05
Identities = 68/284 (23%), Positives = 117/284 (41%), Gaps = 43/284 (15%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIA 74
+P EL L T G+P+ L C Q + +D +AL ++S ++
Sbjct: 2219 QPTELSL-------TPGAPMELLCDA----QGTPQPNITWHKDGQALTRLENNSRATRVL 2267
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEG---DRLV 131
+ D G Y C A++ A + +S R ++ V P G + + G +LV
Sbjct: 2268 RV--RDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-------PRGPRFVVGLAPGQLV 2318
Query: 132 LICSV-AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGY 189
L CSV A IT W++ + L + TQ + ++ ++ +D+ Y C A N
Sbjct: 2319 LECSVEAEPAPKIT--WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNA- 2375
Query: 190 GPSPSGLVSITVRIPVSR-PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G S+ R+ + P + P +V L C+A P++ W + +
Sbjct: 2376 ----AGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW-RKDRVP 2430
Query: 249 LGSRSA-----PSGGGASFNLS-LTEEHSGNYSCEANNGLGAQR 286
L RS P G S + + + +G+Y C A+N G+ R
Sbjct: 2431 LDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDR 2471
Score = 45.4 bits (106), Expect = 8e-05
Identities = 53/228 (23%), Positives = 93/228 (40%), Gaps = 21/228 (9%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
+LQ+ D G Y C+A ++ R + V P +P + + G
Sbjct: 275 QLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV---PPTIEGAGGRPYVVKAVAGRP 331
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYYCVAE 186
+ L C VA G T W+ GL + + L + + S E+ + Y CVA
Sbjct: 332 VALEC-VARGHPSPTLSWHHE--GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 388
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRA-PRAQAAVEDVLELHCEALRGSPPILYWFYH- 244
+ P+ ++ +V + V +L+ + V LEL C+A P + W +
Sbjct: 389 S---PAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 445
Query: 245 ---EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
E++ G + A G + ++ E +HSG ++C+A N G +E
Sbjct: 446 RPAEELA-GVQVASQG--TTLHIDHVELDHSGLFACQATNEAGTAGAE 490
Score = 45.4 bits (106), Expect = 8e-05
Identities = 72/310 (23%), Positives = 107/310 (34%), Gaps = 32/310 (10%)
Query: 54 FFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRV 108
+++D++AL G + LQ+ D+G Y CEA A R Q V
Sbjct: 1689 WYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG------RDQKLVQLS 1742
Query: 109 PVADVSLETQPPGGQ----VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL 164
+ + P G Q V GD+ VL C + T WYK L L +TQ
Sbjct: 1743 VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETD-ALPEPTVTWYKDGQPLVLAQRTQALR 1801
Query: 165 TAE-YEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE- 222
+ EI + SD Y C N G + ++TV++P + P+ + +
Sbjct: 1802 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR-TFTLTVQVPPT-----FENPKTETVSQV 1855
Query: 223 --DVLELHCEALRGSPPILYWFYHEDITLGS--RSAPSGGGASFNLSLTEEHSGNYSCEA 278
L L C+ P + W S S GG L +G Y+C A
Sbjct: 1856 AGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 1915
Query: 279 NNGLGAQRSEAVTLNFTGRRSARDPLRSLPSPLPQEFTYLNSPTPGQLQP----IYENEP 334
N R + V R + L + L+ GQ P + + P
Sbjct: 1916 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSP 1975
Query: 335 REQSVAVHGR 344
Q + H R
Sbjct: 1976 LGQDMGPHLR 1985
Score = 43.1 bits (100), Expect = 4e-04
Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 12/173 (6%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQ+ A+ D+G Y C A+ A S ++ +H VP ++ + PP V
Sbjct: 2355 LQLQALSTADSGDYSCTARNAAGST--SVAFRVEIHTVP----TIRSGPPAVNVSVNQTA 2408
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGY 189
+L C A G W K V L+ +S L I V DA Y C+A N
Sbjct: 2409 LLPCQ-ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSA 2467
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWF 242
G G + P P L CEA P++ W+
Sbjct: 2468 GSDRQGRDLRVLEPPAIAP----SPSNLTLTAHTPALLPCEASGSPKPLVVWW 2516
Score = 41.2 bits (95), Expect = 0.001
Identities = 61/262 (23%), Positives = 97/262 (37%), Gaps = 18/262 (6%)
Query: 30 EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-----LQIAAMWKEDTGSY 84
E +P L C + D ++R+ + L G S LQI + E+ G Y
Sbjct: 1482 ENNPAYLYCDTNAIPPPD----LTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRY 1537
Query: 85 WCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDIT 144
C+A + ++ V PV E V + L C A+G T
Sbjct: 1538 SCKASNEVGEDWL--HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCP-ALGNPVPT 1594
Query: 145 FLWYKGAVGLNLQSKTQRSLTAEY-EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRI 203
W + + + + Q + ++ + +DA Y CVAEN G S T+R+
Sbjct: 1595 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAG---SAEKLFTLRV 1651
Query: 204 PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY-HEDITLGSRSAPSGGGASF 262
V I L + A + + L C+ P + W+ + ++LG G +
Sbjct: 1652 QVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTL 1711
Query: 263 NLSLTE-EHSGNYSCEANNGLG 283
L SG Y+CEA N G
Sbjct: 1712 QLGRARLSDSGMYTCEALNAAG 1733
Score = 37.7 bits (86), Expect = 0.016
Identities = 59/263 (22%), Positives = 113/263 (42%), Gaps = 20/263 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQF-QFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQ 89
GSP+ LTC + + + + + ++ A+ S +LQ++ + G+Y C A+
Sbjct: 1857 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAE 1916
Query: 90 TMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQVMEGDRLVLICSV-AMGTGDITFLW 147
++ + + V R+ + V+ E V+EG + L C D+ +L
Sbjct: 1917 NTQAEARKDFVVAVLVAPRIRSSGVAREHH-----VLEGQEVRLDCEADGQPPPDVAWLK 1971
Query: 148 YKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVS 206
+G ++ + L + +R SDA Y CVA N G + L ++ V +P
Sbjct: 1972 DGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG-EDARLHTVNVLVP-- 2028
Query: 207 RPILMLRAPRAQAAVE---DVLELHCEALRGSPPILYWFYHE--DITLGSRSAPSGGGAS 261
P + A + V +++ + C +RGSPPI + + + L R+ G G +
Sbjct: 2029 -PTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHT 2086
Query: 262 FNLSLTE-EHSGNYSCEANNGLG 283
+S + +G ++C A + G
Sbjct: 2087 LRISKVQLADAGIFTCVAASPAG 2109
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 63.2 bits (152), Expect = 4e-10
Identities = 64/238 (26%), Positives = 92/238 (38%), Gaps = 20/238 (8%)
Query: 61 LGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPP 120
L P SSS KL+I A + D G+Y C A S Q+ V P T+ P
Sbjct: 623 LAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQL-----TELP 675
Query: 121 GGQVMEGDRLVLICSVAMGTGDITFLWYKG-------AVGLNLQSKTQRSLTAEYEIPSV 173
+E R L+ A G T W +G +G S++++ + SV
Sbjct: 676 RDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESV 735
Query: 174 RESDAEQYYCVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
D Y C A N +G + +T P P + AP + + L C L
Sbjct: 736 APEDQAPYVCEARNVFGKVQAEARLIVTGHAP---PQIASSAPTVRVLEGQPVSLPCIVL 792
Query: 233 RGSP-PILYWFYH-EDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSE 288
G P P +W + GSR + G+ +EH+G YSC A N G+Q +
Sbjct: 793 AGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRD 850
Score = 58.9 bits (141), Expect = 7e-09
Identities = 60/228 (26%), Positives = 91/228 (39%), Gaps = 23/228 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I + ED G+Y C+A + + + + + ++ VS V G+
Sbjct: 545 LIIQGVAPEDAGNYSCQA----TNEVGTDQETVTLYYTDPPSVSAVNAVV--LVAVGEEA 598
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
VL+C A G +WY+G GL + + S + + IP+ +E DA Y C A N G
Sbjct: 599 VLVCE-ASGVPPPRVIWYRG--GLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELG 655
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
+ S +++ V + PR + L C A PP + W + L
Sbjct: 656 DA-----SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL 710
Query: 250 G--------SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
G SRS G F S+ E Y CEA N G ++EA
Sbjct: 711 GLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEA 758
Score = 42.7 bits (99), Expect = 5e-04
Identities = 86/325 (26%), Positives = 120/325 (36%), Gaps = 63/325 (19%)
Query: 16 PAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK----L 71
P ++ A EG PV+L C + + + + +D R L PG S + L
Sbjct: 767 PPQIASSAPTVRVLEGQPVSLPC---IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSL 823
Query: 72 QIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINV----HRVPVADVSLETQPPGGQVMEG 127
+ +E G Y C A A R + V H ++ E P
Sbjct: 824 HLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPAS------ 877
Query: 128 DRLVLICSVAMGTGDITFLWYKGAVGLNLQ------SKTQRSLTAEYEIPSVRESDAEQY 181
L C VA G T W K L + SK L A+ PS + DA Y
Sbjct: 878 ----LPC-VASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQ---PSAQ--DAGAY 927
Query: 182 YCVAENGYGPSPSGLVSITVRIPVS-RPILMLRAPR-------AQAAVEDVLELHCEALR 233
C A N G S S +R+ V+ +P + + R A + + L CEA
Sbjct: 928 VCTATNTVGFS-----SQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKG 982
Query: 234 GSPPILYWFYHEDITLGSRSAPS-----GGGASFNLSLTEEH---SGNYSCEANNGLGAQ 285
PP++ W T SR P G S +L L + SG+Y C A+N G+
Sbjct: 983 SPPPLVTW------TKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGS- 1035
Query: 286 RSEAVTLNFTGRRSARDPLRSLPSP 310
S L GR S + +SLP P
Sbjct: 1036 ASHRYVLGVQGRTSWQP--QSLPVP 1058
Score = 42.4 bits (98), Expect = 7e-04
Identities = 61/263 (23%), Positives = 96/263 (36%), Gaps = 21/263 (7%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-----SSPKLQIAAMWKEDTGSYW 85
G L+C++ +A + + RD R L + L+I+ + D G Y
Sbjct: 414 GETAVLSCRV----LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 469
Query: 86 CEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITF 145
C A A+ V R+ + V P + +Q +G + + CS A G
Sbjct: 470 CVASN-ANGVTRAS-VWLLVREAPQVSIHTSSQ----HFSQGVEVKVSCS-ASGYPTPHI 522
Query: 146 LWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPV 205
W + + L S+ I V DA Y C A N G ++T+
Sbjct: 523 SWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQE---TVTLYYTD 579
Query: 206 SRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS 265
+ + A A E+ + L CEA PP + W Y + + S G +
Sbjct: 580 PPSVSAVNAVVLVAVGEEAV-LVCEASGVPPPRVIW-YRGGLEMILAPEGSSSGKLRIPA 637
Query: 266 LTEEHSGNYSCEANNGLGAQRSE 288
E +G Y+C A N LG +E
Sbjct: 638 AQERDAGTYTCRAVNELGDASAE 660
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 62.4 bits (150), Expect = 6e-10
Identities = 69/297 (23%), Positives = 105/297 (35%), Gaps = 52/297 (17%)
Query: 22 IASPSHPTEGSPVTLTCKMPF----------------------LQSSDAQFQFCFFRDTR 59
I P E VTLTC + F + S+ + F R
Sbjct: 145 IQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEGVPMRQAAVTSTSLTIKSVFTRSEL 204
Query: 60 ALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
P WS K+ C+ Q K L + Q+NV P ++ + P
Sbjct: 205 KFSPQWSHHGKIVT------------CQLQDADGKFLSNDTVQLNVKHTPKLEIKVT--P 250
Query: 120 PGGQVMEGDRLVLICSVAMGTGDITFL-WYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
V EGD + + C V+ + T + W K L Q+ T + V + +
Sbjct: 251 SDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQN------TFTLNLREVTKDQS 304
Query: 179 EQYYCVAENGYGPSPSGLVSITVRI-PVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
+Y C N GP S V + V+ P + +L +P + + + L C +L P
Sbjct: 305 GKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQILHSPAVEGSQVEFL---CMSLANPLP 361
Query: 238 ILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTLN 293
Y +YH + R+ + H+G YSC A N LG QR L+
Sbjct: 362 TNYTWYHNGKEMQGRTEEK----VHIPKILPWHAGTYSCVAENILGTGQRGPGAELD 414
Score = 43.9 bits (102), Expect = 2e-04
Identities = 63/282 (22%), Positives = 106/282 (37%), Gaps = 41/282 (14%)
Query: 21 LIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAM---- 76
+I +P EG VTL+C S ++++ G P L + +
Sbjct: 425 VIQNPMPIREGDTVTLSCNYNSSNPSVTRYEW--------KPHGAWEEPSLGVLKIQNVG 476
Query: 77 WKEDT-----GSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
W T + WC + AS V +NV P DV + P ++ G+ +
Sbjct: 477 WDNTTIACAACNSWC---SWASPVA------LNVQYAP-RDVRVRKIKPLSEIHSGNSVS 526
Query: 132 LICSVAMG-TGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
L C + ++ F W K L +S + S+ DA Y C N G
Sbjct: 527 LQCDFSSSHPKEVQFFWEKNGRLLGKES--------QLNFDSISPEDAGSYSCWVNNSIG 578
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLG 250
+ S ++ V + R + + +P Q L CE+ +PP+ ++ + +
Sbjct: 579 QTASKAWTLEV-LYAPRRLRVSMSPGDQVMEGKSATLTCES-DANPPVSHYTWFD---WN 633
Query: 251 SRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
++S P + +HSG Y C+ N +G RS TL
Sbjct: 634 NQSLPYHSQKLRLEPVKVQHSGAYWCQGTNSVGKGRSPLSTL 675
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 61.6 bits (148), Expect = 1e-09
Identities = 65/299 (21%), Positives = 121/299 (40%), Gaps = 31/299 (10%)
Query: 30 EGSPVTLTCKMPFLQSSDAQF-----QFCFFRDTRALGPGW-------SSSPKLQIAAMW 77
EG T++C++ S Q Q +FRD R L SS K+ + +
Sbjct: 56 EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
D G Y+C+ T + + + + R + D+ +T +EG+ + + C+
Sbjct: 116 ISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDT------AVEGEEIEVNCTAM 169
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR-----SLTAEYEIPSVRESDAEQYYCVAENGYGPS 192
T W+KG L +S+ + ++T++ + +E D C E+ P+
Sbjct: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH---PA 226
Query: 193 PSGLVS----ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G + + V+ I M + D LEL CEA+ P++ + D
Sbjct: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
Query: 249 LGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSL 307
+ + SG N +L + +G Y CEA+N +G S+ + + R +R++
Sbjct: 287 MPQHAVLSGPNLFIN-NLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAV 344
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 61.2 bits (147), Expect = 1e-09
Identities = 69/314 (21%), Positives = 125/314 (39%), Gaps = 38/314 (12%)
Query: 30 EGSPVTLTCKMPFLQSSDAQF-----QFCFFRDTRALGPGW-------SSSPKLQIAAMW 77
EG T++C++ S Q Q +FRD R L SS K+ + +
Sbjct: 56 EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
D G Y+C+ T + + + + R + D+ +T +EG+ + + C+
Sbjct: 116 ISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDT------AVEGEEIEVNCTAM 169
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR-----SLTAEYEIPSVRESDAEQYYCVAENGYGPS 192
T W+KG L +S+ + ++T++ + +E D C E+ P+
Sbjct: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH---PA 226
Query: 193 PSGLVS----ITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDIT 248
+G + + V+ I M + D LEL CEA+ P++ + D
Sbjct: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
Query: 249 LGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSLP 308
+ + SG N +L + +G Y CEA+N +G S+ + + DP ++P
Sbjct: 287 MPQHAVLSGPNLFIN-NLNKTDNGTYRCEASNIVGKAHSDYMLYVY-------DPPTTIP 338
Query: 309 SPLPQEFTYLNSPT 322
P T + T
Sbjct: 339 PPTTTTTTTTTTTT 352
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 60.8 bits (146), Expect = 2e-09
Identities = 80/342 (23%), Positives = 134/342 (39%), Gaps = 36/342 (10%)
Query: 6 LLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGW 65
++++ A P + + +S TEG + L C + + A Q ++R +L P
Sbjct: 2040 VVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVV----AGSAHAQVTWYRRGGSLPPHT 2095
Query: 66 S-SSPKLQIAAMWKEDTGSYWCEAQ--------TMASKVLRSRRSQINVHRVPVADVSLE 116
+L++ + D+G Y C + ++ VL S + VP + +
Sbjct: 2096 QVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIR 2155
Query: 117 TQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRES 176
+P V EG L L C V G W+K L + +T SL ++ V +
Sbjct: 2156 IEPSSSHVAEGQTLDLNC-VVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQ---VTPA 2211
Query: 177 DAEQYYCVAENGYGP-SPSGLVSITVR-IPVSRPILMLRAPRAQAAVEDVLELHCEALRG 234
D+ +Y C GP S LV+I IP P + + + + A L+L C
Sbjct: 2212 DSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQ 2271
Query: 235 SPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNF 294
+ + W Y +L +R G + + +G Y C A+NG+ A ++T+
Sbjct: 2272 AHAQVTW-YKRGGSLPARHQVRGSRL-YIFQASPADAGQYVCRASNGMEA----SITVTV 2325
Query: 295 TGRRSAR--------DPLRSLPSP---LPQEFTYLNSPTPGQ 325
TG + A P+R PS + LN PGQ
Sbjct: 2326 TGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQ 2367
Score = 60.8 bits (146), Expect = 2e-09
Identities = 74/321 (23%), Positives = 122/321 (38%), Gaps = 28/321 (8%)
Query: 23 ASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-SSPKLQIAAMWKEDT 81
+S S EG + L C L + A Q + + +L +L++ + D+
Sbjct: 2443 SSSSQVAEGQTLDLNC----LVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADS 2498
Query: 82 GSYWCE----AQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
G Y C + T + VL + + +++ + + + G L L C VA
Sbjct: 2499 GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVA 2558
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
T WYK G +L S+ Q + + IP V +D+ +Y C NG G + L+
Sbjct: 2559 -SQAPHTITWYKR--GGSLPSRHQ-IVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLI 2614
Query: 198 -----SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
S + +P P + + + L+L+C R I+ W Y +L SR
Sbjct: 2615 VTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITW-YKRGGSLPSR 2673
Query: 253 SAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSLPSPLP 312
G + ++ SG Y C ANN + A + V S P S+P +
Sbjct: 2674 HQTHGSHLRLH-QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIE 2732
Query: 313 QEFTY--------LNSPTPGQ 325
++ LN PGQ
Sbjct: 2733 SSSSHVAEGETLDLNCVVPGQ 2753
Score = 57.8 bits (138), Expect = 2e-08
Identities = 72/292 (24%), Positives = 109/292 (37%), Gaps = 42/292 (14%)
Query: 62 GPGWSSSPKLQI-------AAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS 114
GPG K QI A+ D Y C A + A + + R+ ++VH
Sbjct: 1902 GPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVA--RAVLHVHGG--GGPR 1957
Query: 115 LETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVR 174
++ P QV G + L C A G T W K L Q++++R+ A IP++
Sbjct: 1958 VQVSPERTQVHAGRTVRLYCRAA-GVPSATITWRKEGGSLPPQARSERTDIATLLIPAIT 2016
Query: 175 ESDAEQYYCVAENGYGPSPSGLVSITVRIPV------SRPILMLRAPRAQAAVEDVLELH 228
+DA Y CVA SP+G +++ V S P + + + L+L+
Sbjct: 2017 TADAGFYLCVA-----TSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLN 2071
Query: 229 CEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSE 288
C + GS +Y +L + G ++ SG Y C NG G + +
Sbjct: 2072 C-VVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLP-QVSPADSGEYVCRVENGSGPKEAS 2129
Query: 289 AVTLNFTGRRSARDPLRSLPSPLPQEFTYLNSPTPGQLQPIYENEPREQSVA 340
G S PS +P PG +PI EP VA
Sbjct: 2130 ITVSVLHGTHSG-------PS---------YTPVPGSTRPI-RIEPSSSHVA 2164
Score = 57.8 bits (138), Expect = 2e-08
Identities = 71/297 (23%), Positives = 109/297 (36%), Gaps = 30/297 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI++ D G+Y C AQ + ++ + ++ + V G
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTA 3229
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
L CS A G+ T W K L Q + + IP V + D+ QY C A
Sbjct: 3230 TLRCS-ATGSPAPTIHWSKLRSPLPWQHRLEGDTLI---IPRVAQQDSGQYICNA----- 3280
Query: 191 PSPSGLVSITVRIPVSRPILMLRAP-RAQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
SP+G T+ + V P P A + ++L C A G+PP+ + + +L
Sbjct: 3281 TSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLA-HGTPPLTFQWSRVGSSL 3339
Query: 250 GSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRSLPS 309
R+ F + E+ SG Y C N +G+ + A L ++ P
Sbjct: 3340 PGRATARNELLHFERAAPED-SGRYRCRVTNKVGSAEAFAQLL-----------VQGPPG 3387
Query: 310 PLPQEFTYLNSPTPGQLQPIYENEPREQSVAVH-------GRQQHSSEQKAQKPWGH 359
LP S Q+ P E + SV H G Q ++ Q P GH
Sbjct: 3388 SLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGH 3444
Score = 47.8 bits (112), Expect = 2e-05
Identities = 67/298 (22%), Positives = 113/298 (37%), Gaps = 25/298 (8%)
Query: 19 LFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRAL-GPGWSSSPKLQIAAMW 77
+++ AS SH TEG + L C +P A Q +++ +L + +L++ +
Sbjct: 2927 IYIEASSSHVTEGQTLDLNCVVP----GQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVS 2982
Query: 78 KEDTGSYWCEA------QTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLV 131
D+G Y C A + AS + S+ + +R+ +S++ PP V +G
Sbjct: 2983 PADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISID--PPSSTVQQGQDAS 3040
Query: 132 LICSVAMGTGDITFLWYKGAVGL--NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGY 189
C + G I+ W L N+ S+ I R S+ Y CVA N Y
Sbjct: 3041 FKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIIT---IVGTRPSNHGTYRCVASNAY 3097
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITL 249
G + S +V+++V P + + +L V + L C + W
Sbjct: 3098 GVAQS-VVNLSVHGPPT--VSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPA 3154
Query: 250 GSRSAPSGGGASFNL----SLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDP 303
G S + S +G Y C A N LG + + + TG + P
Sbjct: 3155 KLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAP 3212
Score = 45.4 bits (106), Expect = 8e-05
Identities = 66/264 (25%), Positives = 105/264 (39%), Gaps = 28/264 (10%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS-SSPKLQIAAMWKEDTGSYWCEAQ 89
G+ V C +P SD Q +F++ L PG S L+I + + G+Y C+A
Sbjct: 3414 GASVEFHCAVP----SDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAH 3469
Query: 90 TMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYK 149
K S +Q+ + +P +++ T V+ G + C +A+G W K
Sbjct: 3470 GPWGKAQAS--AQLVIQALPSVLINIRTSVQ--TVVVGHAVEFEC-LALGDPKPQVTWSK 3524
Query: 150 GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPI 209
VG +L+ +S I V +DA QY C A N G + S ++ + +P
Sbjct: 3525 --VGGHLRPGIVQS-GGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMP 3581
Query: 210 LMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNL----S 265
+R P AAV C A P + W + S P N+ S
Sbjct: 3582 QEVRVPAGSAAV-----FPCIASGYPTPDISWSKLDG------SLPPDSRLENNMLMLPS 3630
Query: 266 LTEEHSGNYSCEANNGLGAQRSEA 289
+ + +G Y C A N G ++ A
Sbjct: 3631 VRPQDAGTYVCTATNRQGKVKAFA 3654
Score = 45.1 bits (105), Expect = 1e-04
Identities = 58/289 (20%), Positives = 107/289 (37%), Gaps = 17/289 (5%)
Query: 10 CAPLCEPAELFLIASPSHPT--EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS 67
C P A L + P+ +G +L C++ S + + D R + G
Sbjct: 1668 CLPETNQAPLVVEVHPARSIVPQGGSHSLRCQV---SGSPPHYFYWSREDGRPVPSGTQQ 1724
Query: 68 ---SPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQ- 123
+L ++ D G Y C + + + R+++ V P +++ + Q
Sbjct: 1725 RHQGSELHFPSVQPSDAGVYICTCRNLHQS--NTSRAELLVTEAPSKPITVTVEEQRSQS 1782
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYC 183
V G + IC+ + T +W + G L ++ I +V+ SDA Y C
Sbjct: 1783 VRPGADVTFICTAKSKSPAYTLVWTRLHNG-KLPTRAM-DFNGILTIRNVQLSDAGTYVC 1840
Query: 184 VAENGYGPSPSGLVSITVRIP--VSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
N + G ++ V+ +S P++ + P+ + E C A P L W
Sbjct: 1841 TGSNMFAMD-QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW 1899
Query: 242 FYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAV 290
L +++ GG ++ Y C A++ G Q + AV
Sbjct: 1900 TGGPGGQLPAKAQIHGGILRLP-AVEPTDQAQYLCRAHSSAGQQVARAV 1947
Score = 45.1 bits (105), Expect = 1e-04
Identities = 66/299 (22%), Positives = 111/299 (37%), Gaps = 25/299 (8%)
Query: 23 ASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSS-SPKLQIAAMWKEDT 81
+S SH EG + L C +P A Q + + +L + +L++ + D+
Sbjct: 2733 SSSSHVAEGETLDLNCVVP----GQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADS 2788
Query: 82 GSYWCEAQTM-----ASKVLRSRRSQINVHRVPVADVS--LETQPPGGQVMEGDRLVLIC 134
G Y C AS ++ S + VP + + +P +V EG L L C
Sbjct: 2789 GEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKC 2848
Query: 135 SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGP-SP 193
V G W+K L + + L + V +D+ +Y C G
Sbjct: 2849 -VVPGQAHAQVTWHKRGGNLPARHQVHGPLL---RLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 194 SGLVSITVRIPVSRPI------LMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDI 247
S LV+I P P + + A + L+L+C + G +Y
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC-VVPGQAHAQVTWYKRGG 2963
Query: 248 TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLRS 306
+L +R G +L ++ SG Y C A +G G ++ + T+ + LRS
Sbjct: 2964 SLPARHQTHGSQLRLHL-VSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRS 3021
Score = 38.5 bits (88), Expect = 0.010
Identities = 53/205 (25%), Positives = 85/205 (41%), Gaps = 11/205 (5%)
Query: 111 ADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQ-RSLTAEYE 169
A + +E P V +G L C V+ G+ F W + G + S TQ R +E
Sbjct: 1675 APLVVEVHPARSIVPQGGSHSLRCQVS-GSPPHYFYWSRED-GRPVPSGTQQRHQGSELH 1732
Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELH- 228
PSV+ SDA Y C N + + S + P S+PI + + +V ++
Sbjct: 1733 FPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAP-SKPITVTVEEQRSQSVRPGADVTF 1791
Query: 229 -CEALRGSPP-ILYWFYHEDITLGSRSAPSGGGASF-NLSLTEEHSGNYSCEANNGLGAQ 285
C A SP L W + L +R+ G + N+ L++ +G Y C +N
Sbjct: 1792 ICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSD--AGTYVCTGSNMFAMD 1849
Query: 286 RSEAVTLNFTGRRSARDPLRSLPSP 310
+ A TL+ + P+ S+ P
Sbjct: 1850 QGTA-TLHVQASGTLSAPVVSIHPP 1873
Score = 35.4 bits (80), Expect = 0.081
Identities = 40/167 (23%), Positives = 68/167 (40%), Gaps = 15/167 (8%)
Query: 82 GSYWCEAQTMASKVLRSRRSQIN--VHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMG 139
G+Y C +AS +S +N VH P V P G ++ + V + V+ G
Sbjct: 3087 GTYRC----VASNAYGVAQSVVNLSVHGPPTVSVL----PEGPVWVKVGKAVTLECVSAG 3138
Query: 140 TGDITFLWYK-GAVGLNLQSKTQRSLT--AEYEIPSVRESDAEQYYCVAENGYGPSPSGL 196
+ W + + L+ +T + A +I S + SDA Y C+A+N G + +
Sbjct: 3139 EPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQV 3198
Query: 197 VSITVRIPVSRPILMLRAPRAQAAVE--DVLELHCEALRGSPPILYW 241
I ++ ++A A+ VE L C A P ++W
Sbjct: 3199 EVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHW 3245
Score = 31.6 bits (70), Expect = 1.2
Identities = 44/225 (19%), Positives = 76/225 (33%), Gaps = 22/225 (9%)
Query: 79 EDTGSYWCE-------AQTMASKVLRSRRSQINVHRVPVADV-SLETQPPGGQVMEGDRL 130
ED+G Y C A+ A +++ + +P +++ P G +
Sbjct: 3358 EDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASV 3417
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
C+V G W+K L Q + I ++ +S Y C A +G
Sbjct: 3418 EFHCAVPSDRGT-QLRWFKEGGQLPPGHSVQDGVL---RIQNLDQSCQGTYICQAHGPWG 3473
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLG 250
+ + + +P ++ +R V +E C AL P + W +G
Sbjct: 3474 KAQASAQLVIQALP--SVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWS-----KVG 3526
Query: 251 SRSAPS---GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTL 292
P GG + +G Y C A N G +S + L
Sbjct: 3527 GHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLL 3571
>gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor
[Homo sapiens]
Length = 1070
Score = 60.5 bits (145), Expect = 2e-09
Identities = 54/222 (24%), Positives = 92/222 (41%), Gaps = 15/222 (6%)
Query: 62 GPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
G + +L +A + + D G Y C A +A + RR +N+ V S +P
Sbjct: 367 GRVYQKGHELVLANIAESDAGVYTCHAANLAGQ----RRQDVNITVATVP--SWLKKPQD 420
Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Q+ EG L C + T T +WY+ + ++ S+ + I SV D Y
Sbjct: 421 SQLEEGKPGYLDC-LTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWY 479
Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPIL 239
C++ +P+G + R+ V + P+ Q +E E + C A P +
Sbjct: 480 RCMSS-----TPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTI 534
Query: 240 YWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNG 281
W + +L + G F +T + +GNY+C A+NG
Sbjct: 535 KWERADGSSLPEWVTDNAGTLHF-ARVTRDDAGNYTCIASNG 575
Score = 52.8 bits (125), Expect = 5e-07
Identities = 62/258 (24%), Positives = 93/258 (36%), Gaps = 30/258 (11%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I ++ D Y C + T A + R Q+ + + P Q ME D+
Sbjct: 466 LRINSVEVYDGTWYRCMSSTPAGSIEAQARVQV------LEKLKFTPPPQPQQCMEFDKE 519
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
+ A G T W + + T + T + V DA Y C+A NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFA--RVTRDDAGNYTCIASNG-- 575
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPRAQAAVE-DVLELHCEALRGSPPILYWFYHEDI-- 247
P G + V++ V+ I P + L CEA P++ W + I
Sbjct: 576 --PQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILD 633
Query: 248 --TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRSARDPLR 305
LG R G+ + E SG Y+C A N + +EA PL
Sbjct: 634 PTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEA-------------PLY 680
Query: 306 SLPSPLPQEFTYLNSPTP 323
+ P+P+E SP P
Sbjct: 681 VVDKPVPEESEGPGSPPP 698
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/183 (20%), Positives = 83/183 (45%), Gaps = 10/183 (5%)
Query: 79 EDTGSYWCEAQT-MASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+D+G++ C A+ + + RS + N+ + V L+ ++ ++ L C +
Sbjct: 94 QDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHID 153
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ---YYCVAENGYGPSPS 194
G T+ W++ L+ ++ +++++ ++R + E Y C A + +G + S
Sbjct: 154 -GHPRPTYQWFRDGTPLS-DGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 195 GLVSITVRIPVSRPILMLRAPR--AQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
+ T+ I ++ AP+ A E+ + HC+ PP L W + ++ + +R
Sbjct: 212 SQ-NFTLSIADESFARVVLAPQDVVVARYEEAM-FHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 253 SAP 255
S P
Sbjct: 270 SRP 272
Score = 36.2 bits (82), Expect = 0.048
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 12/193 (6%)
Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWY-KGAVGLNLQSKTQRSLTAEYEIPSVRES 176
QP ++G R +L C V G + W GA + + + + + + R
Sbjct: 37 QPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD-RLQ 94
Query: 177 DAEQYYCVAENGYG--PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEAL 232
D+ + CVA + + S S ++ + P++ L+ P ++A ++ + L C
Sbjct: 95 DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVV-LKHPASEAEIQPQTQVTLRCHID 153
Query: 233 RGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLG-AQRSE 288
P WF +S + NL+L EHSG YSC A++ G A S+
Sbjct: 154 GHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQ 213
Query: 289 AVTLNFTGRRSAR 301
TL+ AR
Sbjct: 214 NFTLSIADESFAR 226
>gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor
[Homo sapiens]
Length = 1014
Score = 60.5 bits (145), Expect = 2e-09
Identities = 54/222 (24%), Positives = 92/222 (41%), Gaps = 15/222 (6%)
Query: 62 GPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPG 121
G + +L +A + + D G Y C A +A + RR +N+ V S +P
Sbjct: 367 GRVYQKGHELVLANIAESDAGVYTCHAANLAGQ----RRQDVNITVATVP--SWLKKPQD 420
Query: 122 GQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQY 181
Q+ EG L C + T T +WY+ + ++ S+ + I SV D Y
Sbjct: 421 SQLEEGKPGYLDC-LTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWY 479
Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPIL 239
C++ +P+G + R+ V + P+ Q +E E + C A P +
Sbjct: 480 RCMSS-----TPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTI 534
Query: 240 YWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNG 281
W + +L + G F +T + +GNY+C A+NG
Sbjct: 535 KWERADGSSLPEWVTDNAGTLHF-ARVTRDDAGNYTCIASNG 575
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/183 (20%), Positives = 83/183 (45%), Gaps = 10/183 (5%)
Query: 79 EDTGSYWCEAQT-MASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+D+G++ C A+ + + RS + N+ + V L+ ++ ++ L C +
Sbjct: 94 QDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHID 153
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQ---YYCVAENGYGPSPS 194
G T+ W++ L+ ++ +++++ ++R + E Y C A + +G + S
Sbjct: 154 -GHPRPTYQWFRDGTPLS-DGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 195 GLVSITVRIPVSRPILMLRAPR--AQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSR 252
+ T+ I ++ AP+ A E+ + HC+ PP L W + ++ + +R
Sbjct: 212 SQ-NFTLSIADESFARVVLAPQDVVVARYEEAM-FHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 253 SAP 255
S P
Sbjct: 270 SRP 272
Score = 36.2 bits (82), Expect = 0.048
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 12/193 (6%)
Query: 118 QPPGGQVMEGDRLVLICSVAMGTGDITFLWY-KGAVGLNLQSKTQRSLTAEYEIPSVRES 176
QP ++G R +L C V G + W GA + + + + + + R
Sbjct: 37 QPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD-RLQ 94
Query: 177 DAEQYYCVAENGYG--PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEAL 232
D+ + CVA + + S S ++ + P++ L+ P ++A ++ + L C
Sbjct: 95 DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVV-LKHPASEAEIQPQTQVTLRCHID 153
Query: 233 RGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE---EHSGNYSCEANNGLG-AQRSE 288
P WF +S + NL+L EHSG YSC A++ G A S+
Sbjct: 154 GHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQ 213
Query: 289 AVTLNFTGRRSAR 301
TL+ AR
Sbjct: 214 NFTLSIADESFAR 226
Score = 36.2 bits (82), Expect = 0.048
Identities = 40/172 (23%), Positives = 62/172 (36%), Gaps = 13/172 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I ++ D Y C + T A + R Q+ + + P Q ME D+
Sbjct: 466 LRINSVEVYDGTWYRCMSSTPAGSIEAQARVQV------LEKLKFTPPPQPQQCMEFDKE 519
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
+ A G T W + + T + T + V DA Y C+A NG
Sbjct: 520 ATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFA--RVTRDDAGNYTCIASNG-- 575
Query: 191 PSPSGLVSITVRIPVSRPILMLRAPRAQAAVE-DVLELHCEALRGSPPILYW 241
P G + V++ V+ I P + L CEA P++ W
Sbjct: 576 --PQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW 625
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 58.9 bits (141), Expect = 7e-09
Identities = 59/229 (25%), Positives = 92/229 (40%), Gaps = 19/229 (8%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I +W D G+Y CEA+ K+ + P+ +S P V+EG +L
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGIS----PSVANVIEGQQL 907
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYG 190
L C++ G W K + L I V+ D +Y CVA N G
Sbjct: 908 TLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAG 967
Query: 191 ---PSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV-LELHCEALRGSPPILYWFYHED 246
+ S +V + I + IL + +E + + L C+A P + W +
Sbjct: 968 TNNKTTSVVVHVLPTIQHGQQIL--------STIEGIPVTLPCKASGNPKPSVIWSKKGE 1019
Query: 247 ITLGSRSAPSGG--GASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
+ S + S G G+ + +S E SG Y C A N G A+R +T+
Sbjct: 1020 LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.4 bits (137), Expect = 2e-08
Identities = 70/256 (27%), Positives = 102/256 (39%), Gaps = 20/256 (7%)
Query: 33 PVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWS----SSPKLQIAAMWKEDTGSYWCEA 88
P+TL+C+ L D + +D RA+ SS LQIA + D G Y C A
Sbjct: 4095 PITLSCEADGLPPPDITWH----KDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMA 4150
Query: 89 QTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWY 148
+A S +++ VH P + + V E + +L C VA G W
Sbjct: 4151 ANVAGS--SSTSTKLTVHVPP----RIRSTEGHYTVNENSQAILPC-VADGIPTPAINWK 4203
Query: 149 KGAVGL-NLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSR 207
K V L NL K E + +V D+ Y CVA N G + VS+TV +
Sbjct: 4204 KDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGED-THTVSLTVHV---L 4259
Query: 208 PILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLT 267
P + L L C+A P L W ++ +I + +G ++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVS 4319
Query: 268 EEHSGNYSCEANNGLG 283
+E SG Y C A N +G
Sbjct: 4320 KEDSGTYVCTAENSVG 4335
Score = 51.6 bits (122), Expect = 1e-06
Identities = 61/219 (27%), Positives = 93/219 (42%), Gaps = 21/219 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI+ +ED G+Y C AQ A L + ++NV PV L+ V+ D+
Sbjct: 4043 LQISRAVREDAGTYMCVAQNPAGTAL--GKIKLNVQVPPVISPHLKE-----YVIAVDKP 4095
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENGY 189
+ + A G W+K + ++S QR L++ +I V+ DA Y C+A N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAI-VESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE--LHCEALRGSPPILYWFYHEDI 247
G S S +TV +P +R+ V + + L C A P + W +
Sbjct: 4155 G-SSSTSTKLTVHVPP-----RIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVL 4208
Query: 248 ---TLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG 283
LG +A G ++ E SG Y+C ANN G
Sbjct: 4209 LANLLGKYTAEPYGELILE-NVVLEDSGFYTCVANNAAG 4246
Score = 50.4 bits (119), Expect = 2e-06
Identities = 62/259 (23%), Positives = 102/259 (39%), Gaps = 20/259 (7%)
Query: 39 KMPFLQSSDAQFQFCFFRDTRALGPGW----SSSPKLQIAAMWKEDTGSYWCEAQTMASK 94
++P S F F R+ LG S+S L IA + D G Y C A + A
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGT 507
Query: 95 VLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGL 154
++ PV V P V G+R VL C + D W + +
Sbjct: 508 GRAQTFFDVS-EPPPVIQV-----PNNVTVTPGERAVLTCLIISAV-DYNLTWQRNDRDV 560
Query: 155 NLQSKTQRSLTAEY--EIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILML 212
L + A E+ SV+ +DA +Y+C+ + G S + V +TV+ P ++
Sbjct: 561 RLAEPARIRTLANLSLELKSVKFNDAGEYHCMV-SSEGGSSAASVFLTVQEPPKVTVM-- 617
Query: 213 RAPRAQAAV-EDVLELHCEALRGSPPILYWFYHEDITLGS-RSAPSGGGASFNLSLTEEH 270
P+ Q+ + + C A P + W ++ +GS R + G F + +
Sbjct: 618 --PKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKD 675
Query: 271 SGNYSCEANNGLGAQRSEA 289
+G Y C A+N G + +
Sbjct: 676 AGIYGCLASNSAGTDKQNS 694
Score = 48.9 bits (115), Expect = 7e-06
Identities = 63/266 (23%), Positives = 105/266 (39%), Gaps = 29/266 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS----LETQPPGGQVME 126
LQI +++ G Y C A A ++++ ++ V+ P+ + P ++
Sbjct: 2631 LQILNAQEDNAGRYSCVATNEAGEMIK--HYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRE---SDAEQYYC 183
+ L L C A + WYK G L+S ++ A ++E SD +Y C
Sbjct: 2689 NNTLTLECE-AYAIPSASLSWYKD--GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTC 2745
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPIL-----MLRAPRAQAA----VEDVLELHCEALRG 234
VA N G + +++P S L ML R A + + + L+CE
Sbjct: 2746 VASNIAGEDELDF-DVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAA 2804
Query: 235 SPPILYWFYH-EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAVTL 292
PP L W+ +T + GG + + E +G Y+C A N G +L
Sbjct: 2805 PPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGED-----SL 2859
Query: 293 NFTGRRSARDPLRSLPSPLPQEFTYL 318
+ R ++ S LP+E T L
Sbjct: 2860 QYDVRVLVPPIIKGANSDLPEEVTVL 2885
Score = 47.4 bits (111), Expect = 2e-05
Identities = 68/282 (24%), Positives = 107/282 (37%), Gaps = 34/282 (12%)
Query: 15 EPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGP-----GWSSSP 69
+P E+ ++A G VTL C++ L + ++T+ + P + S
Sbjct: 1085 KPVEISVLA-------GEEVTLPCEVKSLPPPIITWA----KETQLISPFSPRHTFLPSG 1133
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
++I D+G Y C A +A V ++ ++NVH P ++ P +V G R
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNV--TQAVKLNVHVPP----KIQRGPKHLKVQVGQR 1187
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRS-LTAEYEIPSVRESDAEQYYCVAENG 188
+ + C+ A GT W KG + + + S I SDA Y CVA N
Sbjct: 1188 VDIPCN-AQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNI 1246
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV----LELHCEALRGSPPILYWFYH 244
G + IT+ + + L P E V +E C A P + W ++
Sbjct: 1247 AGTDET---EITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHN 1303
Query: 245 EDITLGSR---SAPSGGGASFNLSLTEEHSGNYSCEANNGLG 283
G S G S+T +G Y C A N G
Sbjct: 1304 GRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 47.4 bits (111), Expect = 2e-05
Identities = 60/226 (26%), Positives = 91/226 (40%), Gaps = 12/226 (5%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
S +LQI+ K D Y C A +A + Q+ + S T+ V
Sbjct: 2249 SGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEII---VT 2305
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEY--EIPSVRESDAEQYYC 183
G + L C V G T W K L +++K L + ++ ++ SD +Y C
Sbjct: 2306 RGKSISLECEV-QGIPPPTVTWMKDGHPL-IKAKGVEILDEGHILQLKNIHVSDTGRYVC 2363
Query: 184 VAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE-DVLELHCEALRGSPPILYWF 242
VA N G + ++V P S I R+P + VE + + L CEA P + WF
Sbjct: 2364 VAVNVAGMTDKKY-DLSVHAPPSI-IGNHRSPENISVVEKNSVSLTCEASGIPLPSITWF 2421
Query: 243 YHE-DITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQR 286
++L + GG L T E +G Y+C N G +R
Sbjct: 2422 KDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEER 2467
Score = 46.2 bits (108), Expect = 5e-05
Identities = 68/285 (23%), Positives = 108/285 (37%), Gaps = 42/285 (14%)
Query: 30 EGSPVTLTCKM--------------PFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAA 75
EG PVTL CK + +S A+F + L + +
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSA-------------GADGSLYVVS 1040
Query: 76 MWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVS--LETQPPGGQVMEGDRLVLI 133
E++G Y C A A R + + V D + +P V+ G+ + L
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLP 1100
Query: 134 CSVAMGTGDITFLWYKGAVGLNLQSKTQRSL-TAEYEIPSVRESDAEQYYCVAENGYGPS 192
C V I W K ++ S L + +I R SD+ Y CVA N
Sbjct: 1101 CEVKSLPPPI-ITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATN----- 1154
Query: 193 PSGLVSITVRIPVSRPILMLRAPR-AQAAVEDVLELHCEALRGSP-PILYWFYHEDITL- 249
+G V+ V++ V P + R P+ + V +++ C A +G+P P++ W L
Sbjct: 1155 IAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNA-QGTPLPVITWSKGGSTMLV 1213
Query: 250 -GSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
G + G T +G Y+C A N G +E +TL+
Sbjct: 1214 DGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETE-ITLH 1257
Score = 45.8 bits (107), Expect = 6e-05
Identities = 67/236 (28%), Positives = 94/236 (39%), Gaps = 31/236 (13%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLET--QPPGGQ 123
SS LQIA ED G Y C A A + + Q++VH P SLE +
Sbjct: 1878 SSGRVLQIAKTLLEDAGRYTCVATNAAGET--QQHIQLHVHEPP----SLEDAGKMLNET 1931
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYK------GAVGLNLQSKTQRSLTAEYEIPSVRESD 177
V+ + + L C A G WYK G+ + ++ Q +I S + SD
Sbjct: 1932 VLVSNPVQLECKAA-GNPVPVITWYKDNRLLSGSTSMTFLNRGQ-----IIDIESAQISD 1985
Query: 178 AEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP- 236
A Y CVA N G + S+ V + P + V + + L CEA RG P
Sbjct: 1986 AGIYKCVAINSAGATEL-FYSLQVHV---APSISGSNNMVAVVVNNPVRLECEA-RGIPA 2040
Query: 237 PILYWFYHEDITLGSRS----APSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSE 288
P L W + + S S SGG S +G Y+C A N G ++ +
Sbjct: 2041 PSLTWL-KDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRD 2095
Score = 45.8 bits (107), Expect = 6e-05
Identities = 61/227 (26%), Positives = 82/227 (36%), Gaps = 32/227 (14%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I + DTG Y C A A RR + VH P S+ P V+ +
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGT--DRRRIDLQVHVPP----SIAPGPTNMTVIVNVQT 3821
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNL---QSKTQRSLTAEYEIPSVRESDAEQYYCVAEN 187
L C A G + W K LN+ Q+ + + I S D Y C N
Sbjct: 3822 TLACE-ATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 188 GYGPSPSGLVSITVRIPVS---RPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYH 244
G G V +TV++P S P L A A + C A P ++W +
Sbjct: 3881 GAGDDKR-TVDLTVQVPPSIADEPTDFLVTKHAPAVIT------CTASGVPFPSIHWTKN 3933
Query: 245 EDITLGSRSAPSG-------GGASFNLSLTEEHSGNYSCEANNGLGA 284
G R P G GA L+ H+G Y+C A N G+
Sbjct: 3934 -----GIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGS 3975
Score = 44.7 bits (104), Expect = 1e-04
Identities = 54/222 (24%), Positives = 91/222 (40%), Gaps = 11/222 (4%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI ED G Y C A A + S + + V P+ + P V+
Sbjct: 2833 LQIPRAKVEDAGRYTCVAVNEAGE--DSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSA 2890
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE--YEIPSVRESDAEQYYCVAENG 188
++ C ++ G+ W K L L+ + L+ +I + + +D +Y CVAEN
Sbjct: 2891 LIEC-LSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITDIGRYVCVAENT 2948
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHED-I 247
G S ++ V +P S ++ ++ V + + L CE PP L W +E I
Sbjct: 2949 AG-SAKKYFNLNVHVPPS--VIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPI 3005
Query: 248 TLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSE 288
L + + GG + + + G Y+C A N G + +
Sbjct: 3006 KLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Score = 44.3 bits (103), Expect = 2e-04
Identities = 55/221 (24%), Positives = 89/221 (40%), Gaps = 23/221 (10%)
Query: 79 EDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGG-QVMEGDRLVLIC-SV 136
ED+G Y C A A + + + VH +P T+ PG + +G++L L C +
Sbjct: 4232 EDSGFYTCVANNAAGE--DTHTVSLTVHVLPTF-----TELPGDVSLNKGEQLRLSCKAT 4284
Query: 137 AMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGL 196
+ +T+ + + + S S E I V + D+ Y C AEN G
Sbjct: 4285 GIPLPKLTWTFNNNIIPAHFDSVNGHS---ELVIERVSKEDSGTYVCTAENSVG-----F 4336
Query: 197 VSITVRIPVSRPILMLRAPRAQAAVEDV---LELHCEALRGSPPILYWFYHE-DITLGSR 252
V + V P + + +E + L+CE P + W DI + R
Sbjct: 4337 VKAIGFVYVKEPPVF-KGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHR 4395
Query: 253 SAPSGGGASFNLSLTEEHSGNYSCEANNGLG-AQRSEAVTL 292
G G+ E +G+Y+C A N G +RS ++TL
Sbjct: 4396 IRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTL 4436
Score = 43.5 bits (101), Expect = 3e-04
Identities = 59/228 (25%), Positives = 87/228 (38%), Gaps = 25/228 (10%)
Query: 79 EDTGSYWCEAQTMA-SKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+D G Y C A A + S I ++ V L V GD V+ C +
Sbjct: 674 KDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSEL-------LVALGDITVMECKTS 726
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQR---SLTAEYEIPSVRESDAEQYYCVAENGYGPSPS 194
G W+KG L L+ T L +I ++ DA Y CVA N G + +
Sbjct: 727 -GIPPPQVKWFKG--DLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRA-T 782
Query: 195 GLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSA 254
G +++ V P P+ + + + L C P + W +++ + SR
Sbjct: 783 GKITLDVGSP---PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPF 839
Query: 255 PSGG------GASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTG 296
GA F L+L G Y CEA N G +SE T+ TG
Sbjct: 840 SVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSE-TTVTVTG 886
Score = 43.1 bits (100), Expect = 4e-04
Identities = 57/221 (25%), Positives = 88/221 (39%), Gaps = 23/221 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI D G Y C A A + ++ + V+ P V EG +
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGE--SKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSV 3077
Query: 131 VLIC-SVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRE---SDAEQYYCVAE 186
L C S A+ IT WYK G + T + A+ ++ +++ SD QY C A
Sbjct: 3078 SLECESNAVPPPVIT--WYKN--GRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAI 3133
Query: 187 NGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDV---LELHCEALRGSPPILYWFY 243
N G + V +P S + P + VE + + L C+A PP + W
Sbjct: 3134 NVAGRDDKNF-HLNVYVPPS-----IEGPEREVIVETISNPVTLTCDATGIPPPTIAWLK 3187
Query: 244 HEDITLGSRSAPS---GGGASFNLSLTEEH-SGNYSCEANN 280
+ S S GG+ ++ ++ SGNY+C A+N
Sbjct: 3188 NHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Score = 42.7 bits (99), Expect = 5e-04
Identities = 45/175 (25%), Positives = 66/175 (37%), Gaps = 13/175 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L I D+ +Y C +A +S ++V+ P+ + +L T P QV+ L
Sbjct: 1603 LHIPRAQVSDSATYTCHVANVAGTAEKS--FHVDVYVPPMIEGNLAT-PLNKQVVIAHSL 1659
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE-YEIPSVRESDAEQYYCVAENGY 189
L C A G W K V + + + EI S +E D QY CVA
Sbjct: 1660 TLECKAA-GNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT--- 1715
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQ---AAVEDVLELHCEALRGSPPILYW 241
S +G I + V P + V ++LEL C PP + W
Sbjct: 1716 --SVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMW 1768
Score = 41.2 bits (95), Expect = 0.001
Identities = 45/180 (25%), Positives = 71/180 (39%), Gaps = 11/180 (6%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
S KLQIA D+G+Y C A M K + I +VP + E P V+
Sbjct: 3204 SGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI---QVPPSVAGAEI-PSDVSVL 3259
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQR----SLTAEYEIPSVRESDAEQY 181
G+ + L+C+ A G W K + +T+R + + I SD +Y
Sbjct: 3260 LGENVELVCN-ANGIPTPLIQWLKDGKPI-ASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 182 YCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYW 241
CVA N G + ++ V + + A + V+ + + C A PP + W
Sbjct: 3318 TCVATNPAG-EEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINW 3376
Score = 40.0 bits (92), Expect = 0.003
Identities = 58/225 (25%), Positives = 91/225 (40%), Gaps = 27/225 (12%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQI D G Y C A+ A + +NVH VP + + +++ V+ + +
Sbjct: 2928 LQILNTQITDIGRYVCVAENTAGSA--KKYFNLNVH-VPPSVIGPKSE--NLTVVVNNFI 2982
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQ-----RSLTAEYEIPSVRESDAEQYYCVA 185
L C V+ G W K + L + T R+L +I + SD +Y C+A
Sbjct: 2983 SLTCEVS-GFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL----QIIRAKVSDGGEYTCIA 3037
Query: 186 ENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE-----LHCEALRGSPPILY 240
N G S S+TV +P S + +V +V E L CE+ PP++
Sbjct: 3038 INQAGESKKKF-SLTVYVPPS----IKDHDSESLSVVNVREGTSVSLECESNAVPPPVIT 3092
Query: 241 WFYH-EDITLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLG 283
W+ + IT + G ++ E +G Y C A N G
Sbjct: 3093 WYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG 3137
Score = 39.3 bits (90), Expect = 0.006
Identities = 37/147 (25%), Positives = 56/147 (38%), Gaps = 19/147 (12%)
Query: 59 RALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQ 118
R LG G L I ED G Y C A A V RS + + P+ + +
Sbjct: 4397 RQLGNG-----SLAIYGTVNEDAGDYTCVATNEAGVVERSM--SLTLQSPPI----ITLE 4445
Query: 119 PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
P + G +++L C A G T W + ++ + I ++ D
Sbjct: 4446 PVETVINAGGKIILNCQ-ATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDT 4504
Query: 179 EQYYCVAENGYGPSPSGLVSITVRIPV 205
++ CVA N G S+ VR+PV
Sbjct: 4505 SEFECVARNLMG-------SVLVRVPV 4524
Score = 38.9 bits (89), Expect = 0.007
Identities = 48/210 (22%), Positives = 79/210 (37%), Gaps = 18/210 (8%)
Query: 80 DTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMG 139
DT +Y C A +A K R +NV +++ P ++ VL C +A G
Sbjct: 3686 DTANYTCVASNIAGKTTREFILTVNV------PPNIKGGPQSLVILLNKSTVLEC-IAEG 3738
Query: 140 TGDITFLWYK-GAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVS 198
W K GAV ++ I S +D +Y C+A N G + +
Sbjct: 3739 VPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAG-TDRRRID 3797
Query: 199 ITVRIPVSRPILMLRAPRAQAAVEDV-LELHCEALRGSPPILYWFYHEDITLGSRSAPS- 256
+ V +P S + P + +V L CEA P + W + + ++ S
Sbjct: 3798 LQVHVPPS----IAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSY 3853
Query: 257 ---GGGASFNLSLTEEHSGNYSCEANNGLG 283
G+ +S + + + Y C NG G
Sbjct: 3854 RLLSSGSLVIISPSVDDTATYECTVTNGAG 3883
Score = 38.5 bits (88), Expect = 0.010
Identities = 54/224 (24%), Positives = 87/224 (38%), Gaps = 12/224 (5%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
LQ+ ED+G Y C A A +V S+ + V P + S E + V+ + L
Sbjct: 3491 LQLLKAETEDSGKYTCIASNEAGEV--SKHFILKVLEPPHINGSEEHEEI--SVIVNNPL 3546
Query: 131 VLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE-YEIPSVRESDAEQYYCVAENGY 189
L C +A G W K L + Q E I + + D +Y C+A +
Sbjct: 3547 ELTC-IASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPA 3605
Query: 190 GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVED-VLELHCEALRGSPPILYWFYH-EDI 247
G VR+ V I PR + + + L C++ PP++ W + E +
Sbjct: 3606 GDDDK---EYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERL 3662
Query: 248 TLGSRSAPSGGGASFNLSLTE-EHSGNYSCEANNGLGAQRSEAV 290
R GG ++ + + NY+C A+N G E +
Sbjct: 3663 QATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFI 3706
Score = 38.1 bits (87), Expect = 0.013
Identities = 50/192 (26%), Positives = 77/192 (40%), Gaps = 26/192 (13%)
Query: 63 PGWSSSPK---LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQP 119
PG S S L+I +DTG Y CEA +A K + +N+ P ++ +
Sbjct: 2148 PGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKT--EKNYNVNIWVPP--NIGGSDEL 2203
Query: 120 PGGQVMEGDRLVLICSVAMGTGDITFLW-YKGAVGLNLQSKTQRSLTA--EYEIPSVRES 176
V+EG+ + L+C + G +W KG+ L R L+ + +I +S
Sbjct: 2204 TQLTVIEGNLISLLCE-SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 177 DAEQYYCVAENGYGPSPSG-----LVSITVRIPVSRP--ILMLRAPRAQAAVEDVLELHC 229
DA Y CVA N G + + T+ S P I++ R + L C
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKS--------ISLEC 2314
Query: 230 EALRGSPPILYW 241
E PP + W
Sbjct: 2315 EVQGIPPPTVTW 2326
Score = 37.0 bits (84), Expect = 0.028
Identities = 56/228 (24%), Positives = 82/228 (35%), Gaps = 24/228 (10%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVME---- 126
L I D G Y C A +A + ++I +H V + +PP +
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAG----TDETEITLHVQEPPTVE-DLEPPYNTTFQERVA 1280
Query: 127 GDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE----YEIPSVRESDAEQYY 182
R+ C A GT T W G L + E I SV D +Y
Sbjct: 1281 NQRIEFPCP-AKGTPKPTIKWLHN--GRELTGREPGISILEDGTLLVIASVTPYDNGEYI 1337
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAV--EDVLELHCEALRGSPPILY 240
CVA N G + ++ V +P P++ + +V + L CE PI+
Sbjct: 1338 CVAVNEAGTTERKY-NLKVHVP---PVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 241 WFYHE-DITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQR 286
W+ +T S G L T E +G YSC+A N G +
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQ 1441
Score = 36.6 bits (83), Expect = 0.037
Identities = 54/227 (23%), Positives = 86/227 (37%), Gaps = 19/227 (8%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVM 125
S L++ ED G Y C + A + + + V V + +LE +V
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDV----KVK 2492
Query: 126 EGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAE---YEIPSVRESDAEQYY 182
E + L C V G W+K G LQ + + +I +V+ +Y
Sbjct: 2493 EKQSVTLTCEVT-GNPVPEITWHKD--GQPLQEDEAHHIISGGRFLQITNVQVPHTGRYT 2549
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLE----LHCEALRGSPPI 238
C+A + G S ++ + VS I + + V +L L CEA P
Sbjct: 2550 CLASSPAGHKSR---SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPAT 2606
Query: 239 LYWFYHEDITLGSRSAP--SGGGASFNLSLTEEHSGNYSCEANNGLG 283
+ WF +R+ GG L+ E+++G YSC A N G
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 36.2 bits (82), Expect = 0.048
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 14/120 (11%)
Query: 170 IPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHC 229
+ S + SD +Y CVA N G + + V +P P +M + +EL C
Sbjct: 2070 LTSAQISDTGRYTCVAVNAAGEKQRD-IDLRVYVP---PNIMGEEQNVSVLISQAVELLC 2125
Query: 230 EALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTE------EHSGNYSCEANNGLG 283
++ PP L W L G S N S+ + + +G Y+CEA N G
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLL----KKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 33.9 bits (76), Expect = 0.24
Identities = 51/219 (23%), Positives = 86/219 (39%), Gaps = 14/219 (6%)
Query: 70 KLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDR 129
KL+I + + D G Y C A ++A + + + +++V P + ET VM +
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGE--KEIKYEVDVLVPPAIEGGDETS--YFIVMVNNL 1751
Query: 130 LVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTA-EYEIPSVRESDAEQYYCVAENG 188
L L C V G+ T +W K ++ + + L + I + S+ Y C+A N
Sbjct: 1752 LELDCHVT-GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANT 1810
Query: 189 YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVE-DVLELHCEALRGSPPILYWFYHE-- 245
G +TV +P P + + V+ + L C A P + W +
Sbjct: 1811 AGDHKKEF-EVTVHVP---PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 246 -DITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLG 283
+ G+ S G E +G Y+C A N G
Sbjct: 1867 VNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAG 1905
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 58.2 bits (139), Expect = 1e-08
Identities = 61/239 (25%), Positives = 98/239 (41%), Gaps = 37/239 (15%)
Query: 65 WSSSPKLQIAAMWKE------------DTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD 112
W+S P++++ E D G Y C QT + + + VH VP
Sbjct: 79 WTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPY--TTQVYLIVH-VPARI 135
Query: 113 VSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPS 172
V++ + V EG + L+C +A+G + T W + G + + EI
Sbjct: 136 VNISSPVT---VNEGGNVNLLC-LAVGRPEPTVTWRQLRDGFTSEGEI-------LEISD 184
Query: 173 VRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEAL 232
++ A +Y CV NG +P S V + V+ P + A+ A+ L CEA+
Sbjct: 185 IQRGQAGEYECVTHNGVNSAPD---SRRVLVTVNYPPTITDVTSARTALGRAALLRCEAM 241
Query: 233 RGSPPILYWFYHEDITLGSRSAPS-------GGGASFNLSLTEEHSGNYSCEANNGLGA 284
PP + +Y +D L S +A +++ H GNY+C A N LGA
Sbjct: 242 -AVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGA 299
Score = 38.5 bits (88), Expect = 0.010
Identities = 48/191 (25%), Positives = 71/191 (37%), Gaps = 28/191 (14%)
Query: 16 PAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPK-LQIA 74
PA + I+SP EG V L C + R L G++S + L+I+
Sbjct: 132 PARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW--------RQLRDGFTSEGEILEIS 183
Query: 75 AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVP-VADVSLETQPPGGQVMEGDRLVLI 133
+ + G Y C + SRR + V+ P + DV+ G R L+
Sbjct: 184 DIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALG-------RAALL 236
Query: 134 CSVAMGTGDITFLWYKG--------AVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVA 185
AM F WYK A GL +Q++ RS+ +V Y C A
Sbjct: 237 RCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLL---FANVSARHYGNYTCRA 293
Query: 186 ENGYGPSPSGL 196
N G S + +
Sbjct: 294 ANRLGASSASM 304
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 9/213 (4%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
+T G+Y+C A N +G + A
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA 304
Score = 38.1 bits (87), Expect = 0.013
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451
Query: 241 W 241
W
Sbjct: 452 W 452
Score = 37.0 bits (84), Expect = 0.028
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517
Score = 35.0 bits (79), Expect = 0.11
Identities = 47/188 (25%), Positives = 67/188 (35%), Gaps = 15/188 (7%)
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSV--------RE 175
V +G+ L C A G T WYKG + RS S+ R+
Sbjct: 40 VSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRK 98
Query: 176 SDAEQ--YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
S ++ Y CVA N G + S S+ V I R AV + + C+ R
Sbjct: 99 SRPDEGVYVCVARNYLGEAVSHNASLEVAI--LRDDFRQNPSDVMVAVGEPAVMECQPPR 156
Query: 234 GSP-PILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVT 291
G P P + W + G ++ T + +G Y C N +G + SE
Sbjct: 157 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 216
Query: 292 LNFTGRRS 299
L R S
Sbjct: 217 LTVLERPS 224
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 9/213 (4%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
+T G+Y+C A N +G + A
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA 304
Score = 38.1 bits (87), Expect = 0.013
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451
Query: 241 W 241
W
Sbjct: 452 W 452
Score = 37.0 bits (84), Expect = 0.028
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517
Score = 35.0 bits (79), Expect = 0.11
Identities = 47/188 (25%), Positives = 67/188 (35%), Gaps = 15/188 (7%)
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSV--------RE 175
V +G+ L C A G T WYKG + RS S+ R+
Sbjct: 40 VSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRK 98
Query: 176 SDAEQ--YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
S ++ Y CVA N G + S S+ V I R AV + + C+ R
Sbjct: 99 SRPDEGVYVCVARNYLGEAVSHNASLEVAI--LRDDFRQNPSDVMVAVGEPAVMECQPPR 156
Query: 234 GSP-PILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVT 291
G P P + W + G ++ T + +G Y C N +G + SE
Sbjct: 157 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 216
Query: 292 LNFTGRRS 299
L R S
Sbjct: 217 LTVLERPS 224
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 9/213 (4%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
+T G+Y+C A N +G + A
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA 304
Score = 37.0 bits (84), Expect = 0.028
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 369 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 425
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 426 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 485
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 486 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 514
Score = 36.2 bits (82), Expect = 0.048
Identities = 47/181 (25%), Positives = 66/181 (36%), Gaps = 17/181 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEAS--ATLTVQEPPHFVVK-----PRDQVVALGRT 328
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 329 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 388
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 389 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 448
Query: 241 W 241
W
Sbjct: 449 W 449
Score = 35.0 bits (79), Expect = 0.11
Identities = 47/188 (25%), Positives = 67/188 (35%), Gaps = 15/188 (7%)
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSV--------RE 175
V +G+ L C A G T WYKG + RS S+ R+
Sbjct: 40 VSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRK 98
Query: 176 SDAEQ--YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
S ++ Y CVA N G + S S+ V I R AV + + C+ R
Sbjct: 99 SRPDEGVYVCVARNYLGEAVSHNASLEVAI--LRDDFRQNPSDVMVAVGEPAVMECQPPR 156
Query: 234 GSP-PILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVT 291
G P P + W + G ++ T + +G Y C N +G + SE
Sbjct: 157 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 216
Query: 292 LNFTGRRS 299
L R S
Sbjct: 217 LTVLERPS 224
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 9/213 (4%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
+T G+Y+C A N +G + A
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA 304
Score = 38.1 bits (87), Expect = 0.013
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451
Query: 241 W 241
W
Sbjct: 452 W 452
Score = 37.0 bits (84), Expect = 0.028
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517
Score = 35.0 bits (79), Expect = 0.11
Identities = 47/188 (25%), Positives = 67/188 (35%), Gaps = 15/188 (7%)
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSV--------RE 175
V +G+ L C A G T WYKG + RS S+ R+
Sbjct: 40 VSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRK 98
Query: 176 SDAEQ--YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
S ++ Y CVA N G + S S+ V I R AV + + C+ R
Sbjct: 99 SRPDEGVYVCVARNYLGEAVSHNASLEVAI--LRDDFRQNPSDVMVAVGEPAVMECQPPR 156
Query: 234 GSP-PILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVT 291
G P P + W + G ++ T + +G Y C N +G + SE
Sbjct: 157 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 216
Query: 292 LNFTGRRS 299
L R S
Sbjct: 217 LTVLERPS 224
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 9/213 (4%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 155
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 156 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 215
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 216 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 271
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
+T G+Y+C A N +G + A
Sbjct: 272 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA 304
Score = 38.1 bits (87), Expect = 0.013
Identities = 47/181 (25%), Positives = 65/181 (35%), Gaps = 14/181 (7%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + V P V P QV+ R
Sbjct: 276 LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFV----VKPRDQVVALGRT 331
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 332 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 391
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 392 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 451
Query: 241 W 241
W
Sbjct: 452 W 452
Score = 37.0 bits (84), Expect = 0.028
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 428
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 429 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 488
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 489 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 517
Score = 35.0 bits (79), Expect = 0.11
Identities = 47/188 (25%), Positives = 67/188 (35%), Gaps = 15/188 (7%)
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSV--------RE 175
V +G+ L C A G T WYKG + RS S+ R+
Sbjct: 40 VSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRK 98
Query: 176 SDAEQ--YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
S ++ Y CVA N G + S S+ V I R AV + + C+ R
Sbjct: 99 SRPDEGVYVCVARNYLGEAVSHNASLEVAI--LRDDFRQNPSDVMVAVGEPAVMECQPPR 156
Query: 234 GSP-PILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVT 291
G P P + W + G ++ T + +G Y C N +G + SE
Sbjct: 157 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 216
Query: 292 LNFTGRRS 299
L R S
Sbjct: 217 LTVLERPS 224
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/213 (25%), Positives = 80/213 (37%), Gaps = 9/213 (4%)
Query: 78 KEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVA 137
+ D G Y C A+ + + S V + P V G+ V+ C
Sbjct: 139 RPDEGVYVCVARNYLGEAVSHNASL----EVAILRDDFRQNPSDVMVAVGEPAVMECQPP 194
Query: 138 MGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLV 197
G + T W K L+ + + + I R+SDA +Y CV N G S +
Sbjct: 195 RGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVA 254
Query: 198 SITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSP-PILYWFYHEDITLGSRSAPS 256
+TV + RP + R V+D E CEA RG P P + W + SR
Sbjct: 255 ELTV---LERPSFVKRPSNLAVTVDDSAEFKCEA-RGDPVPTVRWRKDDGELPKSRYEIR 310
Query: 257 GGGASFNLSLTEEHSGNYSCEANNGLGAQRSEA 289
+T G+Y+C A N +G + A
Sbjct: 311 DDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA 343
Score = 37.0 bits (84), Expect = 0.028
Identities = 38/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVAD--VSLETQPPGGQ 123
S + L I + + D G Y C+ +A ++ ++ + V V +AD + Q P Q
Sbjct: 408 SQTGDLTITNVQRSDVGYYICQTLNVAGSII--TKAYLEVTDV-IADRPPPVIRQGPVNQ 464
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQ-SKTQRSLTAEYEIPSVRESDAEQYY 182
+ D ++ VA G+ T LW K V ++ Q S+ ++ +I + D +Y
Sbjct: 465 TVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYT 524
Query: 183 CVAENGYGPSPSGLVSITVRIPVSRPILMLRAPR 216
C+A +PSG + + I V + ++ PR
Sbjct: 525 CIAS-----TPSGEATWSAYIEVQEFGVPVQPPR 553
Score = 36.2 bits (82), Expect = 0.048
Identities = 47/181 (25%), Positives = 66/181 (36%), Gaps = 17/181 (9%)
Query: 71 LQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRL 130
L+I + D GSY C A+ M K S + + V P V P QV+ R
Sbjct: 315 LKIRKVTAGDMGSYTCVAENMVGKAEAS--ATLTVQEPPHFVVK-----PRDQVVALGRT 367
Query: 131 VLICSVAMGTGDITFLWYK-GAVGL-------NLQSKTQRSLTAEYEIPSVRESDAEQYY 182
V A G W + G+ L S+ S T + I +V+ SD Y
Sbjct: 368 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 427
Query: 183 CVAENGYGP-SPSGLVSITVRIPVSRPILMLRAPRAQ-AAVEDVLELHCEALRGSPPILY 240
C N G + +T I P ++ + P Q AV+ L C A P +
Sbjct: 428 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 487
Query: 241 W 241
W
Sbjct: 488 W 488
Score = 35.0 bits (79), Expect = 0.11
Identities = 47/188 (25%), Positives = 67/188 (35%), Gaps = 15/188 (7%)
Query: 124 VMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSV--------RE 175
V +G+ L C A G T WYKG + RS S+ R+
Sbjct: 79 VSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRK 137
Query: 176 SDAEQ--YYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALR 233
S ++ Y CVA N G + S S+ V I R AV + + C+ R
Sbjct: 138 SRPDEGVYVCVARNYLGEAVSHNASLEVAI--LRDDFRQNPSDVMVAVGEPAVMECQPPR 195
Query: 234 GSP-PILYWFYHEDITLGSRSAPSGGGASFNLSLTEEH-SGNYSCEANNGLGAQRSEAVT 291
G P P + W + G ++ T + +G Y C N +G + SE
Sbjct: 196 GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAE 255
Query: 292 LNFTGRRS 299
L R S
Sbjct: 256 LTVLERPS 263
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 56.2 bits (134), Expect = 4e-08
Identities = 60/237 (25%), Positives = 92/237 (38%), Gaps = 25/237 (10%)
Query: 68 SPKLQIAA---------MWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQ 118
SP+LQ++ + + DT SY CE Q S +RRS + V +
Sbjct: 188 SPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVS----ARRSDSVILNVLYGPDAPTIS 243
Query: 119 PPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDA 178
P G+ L L C A + W+ V Q TQ E IP++ +++
Sbjct: 244 PLNTSYRSGENLNLSCHAA-SNPPAQYSWF---VNGTFQQSTQ-----ELFIPNITVNNS 294
Query: 179 EQYYCVAENG-YGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPP 237
Y C A N G + + + +ITV +P + ED + L CE +
Sbjct: 295 GSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSN-PVEDEDAVALTCEPEIQNTT 353
Query: 238 ILYWFYHEDITLGSRSAPSGGGASFN-LSLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
L+W ++ + + R S + LS+T G Y C N L S+ V LN
Sbjct: 354 YLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILN 410
Score = 52.4 bits (124), Expect = 6e-07
Identities = 72/291 (24%), Positives = 123/291 (42%), Gaps = 35/291 (12%)
Query: 15 EPAELFLIASPSHPTEGSP-VTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQI 73
EP + F+ ++ S+P E V LTC+ P +Q++ + ++ + ++L SP+LQ+
Sbjct: 321 EPPKPFITSNNSNPVEDEDAVALTCE-PEIQNTT----YLWWVNNQSL----PVSPRLQL 371
Query: 74 A---------AMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQV 124
+ ++ + D G Y C Q S V S +NV P D ++ P
Sbjct: 372 SNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVILNVLYGP-DDPTIS--PSYTYY 427
Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCV 184
G L L C A Y + N+Q TQ E I ++ E ++ Y C
Sbjct: 428 RPGVNLSLSCHAASNPP----AQYSWLIDGNIQQHTQ-----ELFISNITEKNSGLYTCQ 478
Query: 185 AENGY-GPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFY 243
A N G S + + +ITV + +P + + +D + CE + L+W
Sbjct: 479 ANNSASGHSRTTVKTITVSAELPKPSISSNNSKP-VEDKDAVAFTCEPEAQNTTYLWWVN 537
Query: 244 HEDITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANNGLGAQRSEAVTLN 293
+ + + R S G + L ++T + Y C N + A RS+ VTL+
Sbjct: 538 GQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLD 588
Score = 48.5 bits (114), Expect = 9e-06
Identities = 63/268 (23%), Positives = 107/268 (39%), Gaps = 31/268 (11%)
Query: 31 GSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQT 90
G + L+C +S+ Q+ +F + G S+ +L I + ++GSY C+A
Sbjct: 252 GENLNLSCHA----ASNPPAQYSWFVN----GTFQQSTQELFIPNITVNNSGSYTCQAHN 303
Query: 91 MASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKG 150
+ + R+ + I V+ P T V + D + L C + + T+LW+
Sbjct: 304 SDTGLNRTTVTTITVYAEPPKPFI--TSNNSNPVEDEDAVALTCEPEIQ--NTTYLWWVN 359
Query: 151 AVGLNLQSKTQ-----RSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPV 205
L + + Q R+LT + SV +D Y C +N S V + V
Sbjct: 360 NQSLPVSPRLQLSNDNRTLT----LLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGP 415
Query: 206 SRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLS 265
P + + V L L C A P W +I ++ F +
Sbjct: 416 DDPTISPSYTYYRPGVN--LSLSCHAASNPPAQYSWLIDGNIQQHTQEL-------FISN 466
Query: 266 LTEEHSGNYSCEANNGL-GAQRSEAVTL 292
+TE++SG Y+C+ANN G R+ T+
Sbjct: 467 ITEKNSGLYTCQANNSASGHSRTTVKTI 494
Score = 43.5 bits (101), Expect = 3e-04
Identities = 65/304 (21%), Positives = 117/304 (38%), Gaps = 42/304 (13%)
Query: 15 EPAELFLIASPSHPT---------EGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGW 65
+P L ++ P PT G ++L+C +S+ Q+ + D G
Sbjct: 405 DPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHA----ASNPPAQYSWLID----GNIQ 456
Query: 66 SSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVH-RVPVADVSLETQPPGGQV 124
+ +L I+ + ++++G Y C+A AS R+ I V +P +S P V
Sbjct: 457 QHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKP---V 513
Query: 125 MEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQ-----RSLTAEYEIPSVRESDAE 179
+ D + C + T+LW+ L + + Q R+LT + +V +DA
Sbjct: 514 EDKDAVAFTCEPE--AQNTTYLWWVNGQSLPVSPRLQLSNGNRTLT----LFNVTRNDAR 567
Query: 180 QYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPIL 239
Y C +N + S V++ V PI + P + L L C + P
Sbjct: 568 AYVCGIQNSVSANRSDPVTLDVLYGPDTPI--ISPPDSSYLSGANLNLSCHSASNPSPQY 625
Query: 240 YWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTGRRS 299
W + ++ F +T ++G Y+C +N L R+ ++ + T S
Sbjct: 626 SWRINGIPQQHTQ-------VLFIAKITPNNNGTYACFVSN-LATGRNNSIVKSITVSAS 677
Query: 300 ARDP 303
P
Sbjct: 678 GTSP 681
Score = 42.4 bits (98), Expect = 7e-04
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 8/131 (6%)
Query: 222 EDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNL-SLTEEHSGNYSCEANN 280
+D + CE L+W ++ + + R S G + L ++T + +Y CE N
Sbjct: 160 KDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQN 219
Query: 281 GLGAQRSEAVTLNFTGRRSARDPLRSLPSPLPQEFTYLNSPTPGQLQPIYENEPREQSVA 340
+ A+RS++V LN A P+ P +Y + N P + S
Sbjct: 220 PVSARRSDSVILNVLYGPDA-------PTISPLNTSYRSGENLNLSCHAASNPPAQYSWF 272
Query: 341 VHGRQQHSSEQ 351
V+G Q S+++
Sbjct: 273 VNGTFQQSTQE 283
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,128,233
Number of Sequences: 37866
Number of extensions: 799015
Number of successful extensions: 3803
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 249
Number of HSP's that attempted gapping in prelim test: 2518
Number of HSP's gapped (non-prelim): 1115
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.