Search of human proteins with 226529477

Search of human proteins with 226529477

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226529477 cystatin 9 precursor [Homo sapiens]
         (159 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226529477 cystatin 9 precursor [Homo sapiens]                      333   4e-92
gi|18104940 cystatin 9-like precursor [Homo sapiens]                  110   4e-25
gi|239751973 PREDICTED: hypothetical protein XP_002348052 [Homo ...    56   1e-08
gi|239746455 PREDICTED: hypothetical protein XP_002344215 [Homo ...    55   3e-08
gi|169214772 PREDICTED: similar to hCG1783157 [Homo sapiens]           54   4e-08
gi|19882251 cystatin SN precursor [Homo sapiens]                       47   7e-06
gi|4503105 cystatin SA precursor [Homo sapiens]                        47   9e-06
gi|19882256 cystatin D precursor [Homo sapiens]                        40   6e-04
gi|4503109 cystatin S precursor [Homo sapiens]                         39   0.002
gi|4503107 cystatin C precursor [Homo sapiens]                         34   0.046
gi|55956786 spindle assembly associated Sfi1 homolog isoform a [...    31   0.51 
gi|55956784 spindle assembly associated Sfi1 homolog isoform b [...    31   0.51 
gi|11545731 gigaxonin [Homo sapiens]                                   28   3.3  
gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens]              28   4.3  
gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens]              28   4.3  
gi|5729972 phosphodiesterase 10A isoform 2 [Homo sapiens]              28   4.3  
gi|194595488 phosphodiesterase 10A isoform 1 [Homo sapiens]            28   4.3  
gi|5902118 secreted phosphoprotein 2, 24kDa precursor [Homo sapi...    27   7.4  

>gi|226529477 cystatin 9 precursor [Homo sapiens]
          Length = 159

 Score =  333 bits (854), Expect = 4e-92
 Identities = 159/159 (100%), Positives = 159/159 (100%)

Query: 1   MSSPQRRKAMPWALSLLLMGFQLLVTYAWCSEEEMGGNNKIVQDPMFLATVEFALNTFNV 60
           MSSPQRRKAMPWALSLLLMGFQLLVTYAWCSEEEMGGNNKIVQDPMFLATVEFALNTFNV
Sbjct: 1   MSSPQRRKAMPWALSLLLMGFQLLVTYAWCSEEEMGGNNKIVQDPMFLATVEFALNTFNV 60

Query: 61  QSKEEHAYRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLE 120
           QSKEEHAYRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLE
Sbjct: 61  QSKEEHAYRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLE 120

Query: 121 LNNVRQGISFPQVHSCGCCMGCGVGTGAADKAIPRDKGK 159
           LNNVRQGISFPQVHSCGCCMGCGVGTGAADKAIPRDKGK
Sbjct: 121 LNNVRQGISFPQVHSCGCCMGCGVGTGAADKAIPRDKGK 159


>gi|18104940 cystatin 9-like precursor [Homo sapiens]
          Length = 147

 Score =  110 bits (276), Expect = 4e-25
 Identities = 60/114 (52%), Positives = 75/114 (65%), Gaps = 5/114 (4%)

Query: 10  MPWALSLLLMGFQLLVTYAWCSEEEMGGNNKIVQDPMFLATVEFALNTFNVQSKEEHAYR 69
           + WAL LLL+G Q+L+ YAW   E+   +   V      ATVEFA++TFN QSK+ +AYR
Sbjct: 10  LSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQQSKDYYAYR 69

Query: 70  LLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLELNN 123
           L  +L+SW+E     +   K VFSM L L +T C KFEDDIDNC FQES ELNN
Sbjct: 70  LGHILNSWKE-----QVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNN 118


>gi|239751973 PREDICTED: hypothetical protein XP_002348052 [Homo
           sapiens]
          Length = 537

 Score = 55.8 bits (133), Expect = 1e-08
 Identities = 33/102 (32%), Positives = 59/102 (57%), Gaps = 13/102 (12%)

Query: 29  WCSEEEMGGNNKIVQ-DPMFLATVEFALNTFNVQSKEEHAYRLLRVLSSWR--------- 78
           +C+E     ++KI++    F+A++EFA+  FN  + EE+ +RLL V  + +         
Sbjct: 373 YCAEHPHLDHSKIIRRHQYFVASMEFAVAQFNEDNMEEYTHRLLEVQRAQQKVSGSHFVH 432

Query: 79  -EDSMDRKWRGKMVFSM--NLQLRQTVCRKFEDDIDNCPFQE 117
            ++S+ R    K V     +L++  T+C+K+++DIDNCP QE
Sbjct: 433 SQNSLHRLNSSKPVVMAAGDLEMGLTICKKYDEDIDNCPLQE 474


>gi|239746455 PREDICTED: hypothetical protein XP_002344215 [Homo
           sapiens]
          Length = 537

 Score = 54.7 bits (130), Expect = 3e-08
 Identities = 32/102 (31%), Positives = 58/102 (56%), Gaps = 13/102 (12%)

Query: 29  WCSEE-EMGGNNKIVQDPMFLATVEFALNTFNVQSKEEHAYRLLRVLSSWR--------- 78
           +C+E   +  + +I +   F+A++EFA+  FN  + EE+ +RLL V  + +         
Sbjct: 373 YCAEHPHLDHSKRIRRHQYFVASMEFAVAQFNEDNMEEYTHRLLEVQRAQQKVSGSHFVH 432

Query: 79  -EDSMDRKWRGKMVFSM--NLQLRQTVCRKFEDDIDNCPFQE 117
            ++S+ R    K V     +L++  T+C+K+++DIDNCP QE
Sbjct: 433 SQNSLHRLNSSKPVVMAAGDLEMGLTICKKYDEDIDNCPLQE 474


>gi|169214772 PREDICTED: similar to hCG1783157 [Homo sapiens]
          Length = 538

 Score = 54.3 bits (129), Expect = 4e-08
 Identities = 31/102 (30%), Positives = 60/102 (58%), Gaps = 13/102 (12%)

Query: 29  WCSEE-EMGGNNKIVQDPMFLATVEFALNTFNVQSKEEHAYRLLRVLSSWR--------- 78
           +C+E   +  + +I +   F+A++EFA+  FN  + EE+ +RLL V  + +         
Sbjct: 374 YCAEHPHLDHSKRIRRHQYFVASMEFAVAQFNEDNMEEYTHRLLEVQRAQQKVSGSHFVH 433

Query: 79  -EDSMDRKWRGK--MVFSMNLQLRQTVCRKFEDDIDNCPFQE 117
            ++S+ R    K  ++ + +L++  T+C+K+++DIDNCP QE
Sbjct: 434 SQNSLHRLNSSKPGVMAAGDLEMGLTICKKYDEDIDNCPLQE 475


>gi|19882251 cystatin SN precursor [Homo sapiens]
          Length = 141

 Score = 47.0 bits (110), Expect = 7e-06
 Identities = 32/112 (28%), Positives = 59/112 (52%), Gaps = 11/112 (9%)

Query: 15  SLLLMGFQLLVTYAWCSEEEM-----GGNNKIVQDPMFLATVEFALNTFNVQSKEEHAYR 69
           +LLL+   L V  AW  +EE      G  N  + D      + FA++ +N  +K+++  R
Sbjct: 7   TLLLLLATLAVALAWSPKEEDRIIPGGIYNADLNDEWVQRALHFAISEYNKATKDDYYRR 66

Query: 70  LLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLEL 121
            LRVL + R+ ++     G + +  ++++ +T+C K + ++D C F E  EL
Sbjct: 67  PLRVLRA-RQQTV-----GGVNYFFDVEVGRTICTKSQPNLDTCAFHEQPEL 112


>gi|4503105 cystatin SA precursor [Homo sapiens]
          Length = 141

 Score = 46.6 bits (109), Expect = 9e-06
 Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 12/118 (10%)

Query: 10  MPWAL-SLLLMGFQLLVTYAWCSEEEM-----GGNNKIVQDPMFLATVEFALNTFNVQSK 63
           M W L +LLL+     V  AW  +EE      G  +  + D      + F ++ +N  ++
Sbjct: 1   MAWPLCTLLLLLATQAVALAWSPQEEDRIIEGGIYDADLNDERVQRALHFVISEYNKATE 60

Query: 64  EEHAYRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLEL 121
           +E+  RLLRVL + RE  +     G + +  ++++ +T+C K + ++D C F E  EL
Sbjct: 61  DEYYRRLLRVLRA-REQIV-----GGVNYFFDIEVGRTICTKSQPNLDTCAFHEQPEL 112


>gi|19882256 cystatin D precursor [Homo sapiens]
          Length = 142

 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 24/85 (28%), Positives = 50/85 (58%), Gaps = 12/85 (14%)

Query: 38  NNKIVQDPMFLATVEFALNTFN-VQSKEEHAYRLLRVLSSWREDSMDRKWRGKMVFSMNL 96
           N+K VQ       ++FA++ +N V +K+E+  R L+V++++++        G + +  N+
Sbjct: 40  NDKSVQ-----CALDFAISEYNKVINKDEYYSRPLQVMAAYQQIV------GGVNYYFNV 88

Query: 97  QLRQTVCRKFEDDIDNCPFQESLEL 121
           +  +T C K + ++DNCPF +  +L
Sbjct: 89  KFGRTTCTKSQPNLDNCPFNDQPKL 113


>gi|4503109 cystatin S precursor [Homo sapiens]
          Length = 141

 Score = 38.5 bits (88), Expect = 0.002
 Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 11/112 (9%)

Query: 15  SLLLMGFQLLVTYAWCSEEEM-----GGNNKIVQDPMFLATVEFALNTFNVQSKEEHAYR 69
           +LLL+   L    A  S+EE      G  +  + D      + FA++ +N  +++E+  R
Sbjct: 7   TLLLLMATLAGALASSSKEENRIIPGGIYDADLNDEWVQRALHFAISEYNKATEDEYYRR 66

Query: 70  LLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLEL 121
            L+VL + RE +      G + +  ++++ +T+C K + ++D C F E  EL
Sbjct: 67  PLQVLRA-REQTF-----GGVNYFFDVEVGRTICTKSQPNLDTCAFHEQPEL 112


>gi|4503107 cystatin C precursor [Homo sapiens]
          Length = 146

 Score = 34.3 bits (77), Expect = 0.046
 Identities = 17/71 (23%), Positives = 39/71 (54%), Gaps = 6/71 (8%)

Query: 51  VEFALNTFNVQSKEEHAYRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDI 110
           ++FA+  +N  S + +  R L+V+ + ++          + + ++++L +T C K + ++
Sbjct: 53  LDFAVGEYNKASNDMYHSRALQVVRARKQIVAG------VNYFLDVELGRTTCTKTQPNL 106

Query: 111 DNCPFQESLEL 121
           DNCPF +   L
Sbjct: 107 DNCPFHDQPHL 117


>gi|55956786 spindle assembly associated Sfi1 homolog isoform a
           [Homo sapiens]
          Length = 1242

 Score = 30.8 bits (68), Expect = 0.51
 Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 1/44 (2%)

Query: 63  KEEHAYRLLR-VLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRK 105
           + +H  +LLR  L  W+E++M R    K  F  +   R+T+C K
Sbjct: 676 ESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSK 719


>gi|55956784 spindle assembly associated Sfi1 homolog isoform b
           [Homo sapiens]
          Length = 1211

 Score = 30.8 bits (68), Expect = 0.51
 Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 1/44 (2%)

Query: 63  KEEHAYRLLR-VLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRK 105
           + +H  +LLR  L  W+E++M R    K  F  +   R+T+C K
Sbjct: 645 ESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSK 688


>gi|11545731 gigaxonin [Homo sapiens]
          Length = 597

 Score = 28.1 bits (61), Expect = 3.3
 Identities = 13/20 (65%), Positives = 16/20 (80%)

Query: 62 SKEEHAYRLLRVLSSWREDS 81
          S  +HA RLLR LSS+RE+S
Sbjct: 8  SDPQHAARLLRALSSFREES 27


>gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens]
          Length = 1562

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 16/59 (27%)

Query: 87   RGKMVFSMNLQLRQTVCRKFEDDIDNCPFQE------------SLELNNVRQGISFPQV 133
            RG+ VF   L+    +C KF  ++D CP                L +N V QG++ P V
Sbjct: 1218 RGRGVFHNGLK----ICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGVAVPDV 1272


>gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens]
          Length = 1560

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 16/59 (27%)

Query: 87   RGKMVFSMNLQLRQTVCRKFEDDIDNCPFQE------------SLELNNVRQGISFPQV 133
            RG+ VF   L+    +C KF  ++D CP                L +N V QG++ P V
Sbjct: 1216 RGRGVFHNGLK----ICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGVAVPDV 1270


>gi|5729972 phosphodiesterase 10A isoform 2 [Homo sapiens]
          Length = 779

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 15/97 (15%)

Query: 46  MFLATVEFALNTFNVQSKEEHA---YRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTV 102
           MF      AL+  N+  +  H+   YR+     S+       +W+G M F++ ++L    
Sbjct: 403 MFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRL---- 458

Query: 103 CRKFE-DDIDNCPFQESLELNNVRQGISFPQVH-SCG 137
           C++ E    D  PF+      N+  GI    VH SCG
Sbjct: 459 CKEIELFHFDIGPFE------NMWPGIFVYMVHRSCG 489


>gi|194595488 phosphodiesterase 10A isoform 1 [Homo sapiens]
          Length = 789

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 15/97 (15%)

Query: 46  MFLATVEFALNTFNVQSKEEHA---YRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTV 102
           MF      AL+  N+  +  H+   YR+     S+       +W+G M F++ ++L    
Sbjct: 413 MFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRL---- 468

Query: 103 CRKFE-DDIDNCPFQESLELNNVRQGISFPQVH-SCG 137
           C++ E    D  PF+      N+  GI    VH SCG
Sbjct: 469 CKEIELFHFDIGPFE------NMWPGIFVYMVHRSCG 499


>gi|5902118 secreted phosphoprotein 2, 24kDa precursor [Homo
           sapiens]
          Length = 211

 Score = 26.9 bits (58), Expect = 7.4
 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 12/113 (10%)

Query: 6   RRKAMPWALSLLLMGFQLLVTYAWCSEEEMGGNNKIVQDPMFLA-TVEFALNTFNVQSKE 64
           R + M   + +L+M F L + Y  CS     G      DP  L   +  ++   N QS  
Sbjct: 4   RMEKMTMMMKILIM-FALGMNYWSCS-----GFPVYDYDPSSLRDALSASVVKVNSQSLS 57

Query: 65  EHAYRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFE-DDIDNCPFQ 116
            + +R  R  S  R + +D      +V ++   +R+T CRK   +D   C FQ
Sbjct: 58  PYLFRAFRS-SLKRVEVLDEN---NLVMNLEFSIRETTCRKDSGEDPATCAFQ 106


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,010,270
Number of Sequences: 37866
Number of extensions: 226817
Number of successful extensions: 628
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 609
Number of HSP's gapped (non-prelim): 18
length of query: 159
length of database: 18,247,518
effective HSP length: 94
effective length of query: 65
effective length of database: 14,688,114
effective search space: 954727410
effective search space used: 954727410
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.