Search of human proteins with 226492892

Search of human proteins with 226492892

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226492892 coiled-coil domain containing 105 [Homo sapiens]
         (499 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226492892 coiled-coil domain containing 105 [Homo sapiens]        1012   0.0  
gi|156104874 envoplakin [Homo sapiens]                                 40   0.006
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    39   0.011
gi|71061468 centromere protein E [Homo sapiens]                        38   0.024
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    37   0.042
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            36   0.071
gi|50083279 centrosome protein 4 [Homo sapiens]                        36   0.093
gi|24430183 outer dense fiber of sperm tails 2 isoform 2 [Homo s...    35   0.12 
gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo s...    35   0.12 
gi|221219020 NYD-SP11 protein [Homo sapiens]                           35   0.21 
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    35   0.21 
gi|157388975 coiled-coil domain containing 99 [Homo sapiens]           35   0.21 
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]           34   0.35 
gi|21389505 janus kinase and microtubule interacting protein 1 i...    33   0.46 
gi|150456473 janus kinase and microtubule interacting protein 1 ...    33   0.46 
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           33   0.46 
gi|81295809 pericentrin [Homo sapiens]                                 33   0.46 
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                33   0.46 
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    33   0.60 
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    33   0.79 
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    33   0.79 
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]                 33   0.79 
gi|96974985 coiled-coil and C2 domain containing 1A [Homo sapiens]     32   1.0  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    32   1.0  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    32   1.0  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    32   1.0  
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 32   1.3  
gi|169208016 PREDICTED: similar to golgi autoantigen, golgin sub...    32   1.3  
gi|28269672 serologically defined colon cancer antigen 8 [Homo s...    32   1.3  
gi|197313732 pleckstrin homology-like domain, family B, member 2...    32   1.8  

>gi|226492892 coiled-coil domain containing 105 [Homo sapiens]
          Length = 499

 Score = 1012 bits (2616), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 1   MRVLVPPAERSQDTRVGAPAWREAAQAMARTAHILTDRCGQEAVTMWQPKDSVLDPNVAH 60
           MRVLVPPAERSQDTRVGAPAWREAAQAMARTAHILTDRCGQEAVTMWQPKDSVLDPNVAH
Sbjct: 1   MRVLVPPAERSQDTRVGAPAWREAAQAMARTAHILTDRCGQEAVTMWQPKDSVLDPNVAH 60

Query: 61  HLGRAAYIQPWRFRVEMIKGGGTLEKPPPGEGVTLWKGKMKPPAWYARLPLPLHRKARAL 120
           HLGRAAYIQPWRFRVEMIKGGGTLEKPPPGEGVTLWKGKMKPPAWYARLPLPLHRKARAL
Sbjct: 61  HLGRAAYIQPWRFRVEMIKGGGTLEKPPPGEGVTLWKGKMKPPAWYARLPLPLHRKARAL 120

Query: 121 QTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVK 180
           QTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVK
Sbjct: 121 QTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVK 180

Query: 181 LRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKE 240
           LRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKE
Sbjct: 181 LRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKE 240

Query: 241 RLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEA 300
           RLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEA
Sbjct: 241 RLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEA 300

Query: 301 KRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTLGLMRGT 360
           KRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTLGLMRGT
Sbjct: 301 KRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTLGLMRGT 360

Query: 361 ILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTD 420
           ILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTD
Sbjct: 361 ILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTD 420

Query: 421 KLQCHITYLEKNLDELLATHKNLSWGLNCKNIGHEVDGNVVRLRLRQRQPHVCYEQAQRL 480
           KLQCHITYLEKNLDELLATHKNLSWGLNCKNIGHEVDGNVVRLRLRQRQPHVCYEQAQRL
Sbjct: 421 KLQCHITYLEKNLDELLATHKNLSWGLNCKNIGHEVDGNVVRLRLRQRQPHVCYEQAQRL 480

Query: 481 VKDWDPRTPPPRSKSSADP 499
           VKDWDPRTPPPRSKSSADP
Sbjct: 481 VKDWDPRTPPPRSKSSADP 499


>gi|156104874 envoplakin [Homo sapiens]
          Length = 2033

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 50/237 (21%), Positives = 95/237 (40%), Gaps = 45/237 (18%)

Query: 147  INGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKSEKVPD--KADSMLTWEKE 204
            +   +RQL  + +  + R   V++ +++ ++ VKL       EK PD  K+   L W+ +
Sbjct: 1435 VERELRQLTLRIQELEKRPPTVQEKIIM-EEVVKL-------EKDPDLEKSTEALRWDLD 1486

Query: 205  ELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQAVDLMNQPLDKVLEQARRHSW 264
            + K+   ++ R+ +  +V +  L   +      +KE      ++    D+VLE  R   W
Sbjct: 1487 QEKTQVTELNRECKNLQVQIDVLQKAKSQEKTIYKE------VIRVQKDRVLEDERARVW 1540

Query: 265  VNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEAKRL--LVESKDTLVEMAKNEVDVR 322
              L+R  T R   ++                   EA+RL   ++  +TL      E    
Sbjct: 1541 EMLNRERTARQAREE-------------------EARRLRERIDRAETLGRTWSREESEL 1581

Query: 323  EQQLQISDRVCASL--------AQKASETLELKERLNMTLGLMRGTILRCTKYNQEL 371
            ++    +D+ C  L         QK  +TL+L+E   +          +  +  QEL
Sbjct: 1582 QRARDQADQECGRLQQELRALERQKQQQTLQLQEESKLLSQKTESERQKAAQRGQEL 1638


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 70/341 (20%), Positives = 143/341 (41%), Gaps = 70/341 (20%)

Query: 152 RQLLRQREVTDHRLSEVRKGLLINQQSVKL------RGYRPKSEKVP-DKADSMLTWEK- 203
           R++   +E     +SE+ +  L + +  KL      +G + + E +  +K +++L +E  
Sbjct: 424 REVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESL 483

Query: 204 -------------------EELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQA 244
                              +E +SMK++   D+ + +  L+T  + +D L       L+ 
Sbjct: 484 REIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDAL-------LET 536

Query: 245 VDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEAKRL- 303
           V+ +    +K+L Q          +   P  +       +  G Y  + +      K L 
Sbjct: 537 VNRLQGENEKLLSQ----------QELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELE 586

Query: 304 -----LVESKDTLVEMAKN---EVDVREQQLQISDRVCASLAQKASETL----ELKERLN 351
                L E KD  +   KN   E+D   ++ +  +R+   L +K  +T+    EL++++N
Sbjct: 587 GKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVN 646

Query: 352 MTLGLMRGTILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRH--VGTQL 409
              G +  T+    + +Q+L     +++    KV  E  E L   +  +Y+ +  + ++ 
Sbjct: 647 ELTGGLEETLKEKDQNDQKLEKL--MVQ---MKVLSEDKEVLSAEVKSLYEENNKLSSEK 701

Query: 410 PEAAR-----LAQGTDK-LQCHITYLEKNLDELLATHKNLS 444
            + +R     L+Q  D  L+ HIT LEK L  ++    NL+
Sbjct: 702 KQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLN 742


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 47/227 (20%), Positives = 98/227 (43%), Gaps = 18/227 (7%)

Query: 140  LGRAQHQINGRVRQLLRQREVTDHRLSEVR--KGLLINQQSVKLRGYRPKS---EKVPDK 194
            LG  + +++ + ++L  +      RL+E+   K  L N+ S      R K+   EK+   
Sbjct: 861  LGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQT 920

Query: 195  ADSM--LTWEKEELKSMKRKM--ERDMEKSEV--LLKTLASCRDTLNFCFKERLQAVDLM 248
             + +  LT EK++LK ++  +  ERD  KS++   +      ++ L    +   Q  + +
Sbjct: 921  LEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETI 980

Query: 249  NQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEAKRLLVESK 308
            N    K+ E+  R+  +  +   T     QK    D          L     + L  + K
Sbjct: 981  NTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD------LEAKNTQTLTADVK 1034

Query: 309  DT-LVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTL 354
            D  ++E  +    + +++ ++   + + +A+K     +LKE + MT+
Sbjct: 1035 DNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTI 1081


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 37.0 bits (84), Expect = 0.042
 Identities = 63/294 (21%), Positives = 127/294 (43%), Gaps = 26/294 (8%)

Query: 157  QREVTDHRLSEVRKGLLINQ-QSVKLRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMER 215
            Q+E++D        G  I++ + +K +  + KSE      ++  + E EE K ++ ++E 
Sbjct: 1510 QQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEL 1569

Query: 216  DMEKSEVLLKTLASCRDTLNFCFKERLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRT 275
            +  KSEV  K +A   + ++   +  ++ V+ M   LD   E   R+  + L +    + 
Sbjct: 1570 NQVKSEVDRK-IAEKDEEIDQMKRNHIRIVESMQSTLD--AEIRSRNDAIRLKK----KM 1622

Query: 276  QGQKTPPPDPVGTYNPACALALNEAKRLLVESKDT---LVEMAKNEVDVREQQLQISDRV 332
            +G        +   N   A AL   +      KDT   L +  +++ D++EQ   +  R 
Sbjct: 1623 EGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERR- 1681

Query: 333  CASLAQKASETLELK-ERLNMTLGLMRGTILRCTKYNQELYT-------THGLIKGPLSK 384
             A+L Q   E L    E+   +  +    +L  ++  Q L+T       T   ++  +S+
Sbjct: 1682 -ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740

Query: 385  VHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTDKLQ---CHITYLEKNLDE 435
            +  E  + +     R  +      + +AA +A+   K Q    H+  ++KNL++
Sbjct: 1741 IQGEMEDIIQE--ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 1792



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 36/146 (24%), Positives = 66/146 (45%), Gaps = 14/146 (9%)

Query: 121  QTTEVVHAHARGARLTAARLGRAQHQ-INGRVRQLLRQREVTDHRLSEVRKGLLINQQSV 179
            QT + +      A   A + G+ Q Q +  RVR+L  + E    R  E  KGL  +++ V
Sbjct: 1792 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKV 1851

Query: 180  KLRGYRPKSE-----KVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTL 234
            K   Y+ + +     ++ D  D +    + ++KS KR+ E   E+S V L      +  L
Sbjct: 1852 KELTYQTEEDRKNILRLQDLVDKL----QAKVKSYKRQAEEAEEQSNVNLSKFRRIQHEL 1907

Query: 235  NFCFKERLQAVDLMNQPLDKVLEQAR 260
                +E  +  D+    ++K+  ++R
Sbjct: 1908 ----EEAEERADIAESQVNKLRVKSR 1929



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 54/282 (19%), Positives = 106/282 (37%), Gaps = 45/282 (15%)

Query: 204  EELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQAV-----DLMNQPLDKVLEQ 258
            + L+ +K+K+E++  + ++ +  LAS  +T++   K  L+ +     D +++   K  EQ
Sbjct: 1212 DNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKA-KGNLEKMCRALEDQLSEIKTKEEEQ 1270

Query: 259  ARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEAKRLLVESKDTLVEMAKNE 318
             R  + +   RA      G+ +   D   T        L+  K+   +  + L    + E
Sbjct: 1271 QRLINDLTAQRARLQTESGEYSRQLDEKDT----LVSQLSRGKQAFTQQIEELKRQLEEE 1326

Query: 319  VDVRE---QQLQISDRVCASLAQKASETLELKERLNMTLGLMRGTILRC-TKYNQELYTT 374
            +  +      LQ S   C  L ++  E  E K  L   +      + +  TKY  +    
Sbjct: 1327 IKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQ- 1385

Query: 375  HGLIKGPLSKVHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTDKLQCHITYL----- 429
                        LE A+K     ++  + HV     + A L +   +LQ  +  L     
Sbjct: 1386 --------RTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVE 1437

Query: 430  ------------EKNLDELLATHKNLSWGLNCKNIGHEVDGN 459
                        ++N D++LA      W   C+    E++ +
Sbjct: 1438 RTNAACAALDKKQRNFDKILA-----EWKQKCEETHAELEAS 1474


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 36.2 bits (82), Expect = 0.071
 Identities = 60/246 (24%), Positives = 105/246 (42%), Gaps = 29/246 (11%)

Query: 135 LTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKSEKVPDK 194
           L  A L      + G + +L R+R++   RL+E    LL+ ++ + LR   P   + P +
Sbjct: 197 LAPAELEMLSRSLMGTLSKLARERDLGAQRLAE----LLLEREPLCLRPEAPS--RAPAE 250

Query: 195 ADS-----MLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQAVDLMN 249
             S      L   K +L+ +++++E   EK+E+LL + A  +       + R +A  L  
Sbjct: 251 GPSHHLALQLANAKAQLRRLRQELE---EKAELLLDSQAEVQGLEAEIRRLRQEAQALSG 307

Query: 250 QPLDKVLEQARRHSWVNLSRAPT-PRTQGQKTPPPDPVGTYNPACALALNEAKRLLVESK 308
           Q   K  E  R  +     RA   PR Q +     +          L   EA +  +E +
Sbjct: 308 QA--KRAELYREEAEALRERAGRLPRLQEELRRCRE---------RLQAAEAYKSQLEEE 356

Query: 309 DTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERL---NMTLGLMRGTILRCT 365
             L  + +    + E+QL+ +   CA L +   E L L+ RL   +  L  +R  + +  
Sbjct: 357 RVLSGVLEASKALLEEQLEAARERCARLHETQRENLLLRTRLGEAHAELDSLRHQVDQLA 416

Query: 366 KYNQEL 371
           + N EL
Sbjct: 417 EENVEL 422


>gi|50083279 centrosome protein 4 [Homo sapiens]
          Length = 1140

 Score = 35.8 bits (81), Expect = 0.093
 Identities = 29/122 (23%), Positives = 61/122 (50%), Gaps = 6/122 (4%)

Query: 140 LGRAQHQINGRVRQLLRQRE-VTDHRLSEVRKGLLINQQSVKLRGYRPKSEKVPDKADSM 198
           L +A   +  R+R+L+  +E VT   ++   K   + Q+  ++     + E+     + +
Sbjct: 280 LQQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEIDQLAQQLER---HKEEV 336

Query: 199 LTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQAVD--LMNQPLDKVL 256
           L    +EL   K++++R + + + L +T+A  +  LN C KE+ +  D  L+   L+ V+
Sbjct: 337 LETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQKEKERLSDELLVKSDLETVV 396

Query: 257 EQ 258
            Q
Sbjct: 397 HQ 398


>gi|24430183 outer dense fiber of sperm tails 2 isoform 2 [Homo
           sapiens]
          Length = 638

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 28/176 (15%)

Query: 107 ARLPLPLHRKARA----LQTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTD 162
           ARL L L  K +     LQ  +   A A+    TA+ L ++   + G ++  LR +E  +
Sbjct: 286 ARLLLLLQDKDKEVEELLQEIQCEKAQAK----TASELSKSMESMRGHLQAQLRSKEAEN 341

Query: 163 HRLSEVRKGLLI--NQQSVKLRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKS 220
            RL    K L    NQ   ++     + +++  K D      K+ +++ K + E+  E +
Sbjct: 342 SRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYA 401

Query: 221 EVL--------------LKTLASCRDTLNFCFKER----LQAVDLMNQPLDKVLEQ 258
           E L              L TL S R   N   KE+    L+ + L ++  D V +Q
Sbjct: 402 EQLHVQLADKDLYVAEALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQ 457


>gi|24430181 outer dense fiber of sperm tails 2 isoform 1 [Homo
           sapiens]
          Length = 805

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 28/176 (15%)

Query: 107 ARLPLPLHRKARA----LQTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTD 162
           ARL L L  K +     LQ  +   A A+    TA+ L ++   + G ++  LR +E  +
Sbjct: 281 ARLLLLLQDKDKEVEELLQEIQCEKAQAK----TASELSKSMESMRGHLQAQLRSKEAEN 336

Query: 163 HRLSEVRKGLLI--NQQSVKLRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKS 220
            RL    K L    NQ   ++     + +++  K D      K+ +++ K + E+  E +
Sbjct: 337 SRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYA 396

Query: 221 EVL--------------LKTLASCRDTLNFCFKER----LQAVDLMNQPLDKVLEQ 258
           E L              L TL S R   N   KE+    L+ + L ++  D V +Q
Sbjct: 397 EQLHVQLADKDLYVAEALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQ 452


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 54/257 (21%), Positives = 107/257 (41%), Gaps = 32/257 (12%)

Query: 120  LQTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSV 179
            +Q  E +  H         RLGR + Q+  +  +L ++RE   + + E+ K  +I  Q  
Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKK 1837

Query: 180  KL----RGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLN 235
             L    +    + EK+  + +++L + KE L   K+++ +   K  +  K LA   + L 
Sbjct: 1838 NLAQEKKNLAQEKEKLAQRKENLL-YNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLT 1896

Query: 236  FCFKERLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACAL 295
                   Q  + + +  +K+ E  ++   V  S A       Q+               L
Sbjct: 1897 -------QEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQE------------KMKL 1937

Query: 296  ALNEAKRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTLG 355
            AL +A   +V+ K  L    + E+D+ +++  ++  +   LA++    +E KE L+    
Sbjct: 1938 ALEKA---MVQGKKRL----RGELDIAKEEKALNLEM-KRLAEEKMRLVEGKETLSKGET 1989

Query: 356  LMRGTILRCTKYNQELY 372
                   + T+  QEL+
Sbjct: 1990 PETSRQRKMTQVEQELF 2006


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 64/294 (21%), Positives = 124/294 (42%), Gaps = 26/294 (8%)

Query: 157  QREVTDHRLSEVRKGLLINQ-QSVKLRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMER 215
            Q+E++D        G  I++ + VK +    KSE      ++  + E EE K ++ ++E 
Sbjct: 1510 QQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLEL 1569

Query: 216  DMEKSEVLLKTLASCRDTLNFCFKERLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRT 275
            +  KSE+  K +A   + L+   +  L+ V+ M   LD   E   R+  + + +    + 
Sbjct: 1570 NQVKSEIDRK-IAEKDEELDQLKRNHLRVVESMQSTLD--AEIRSRNDALRIKK----KM 1622

Query: 276  QGQKTPPPDPVGTYNPACALALNEAKRLLVESKDT---LVEMAKNEVDVREQQLQISDRV 332
            +G        +   N   A AL   +      KDT   L +  + + D++EQ   +  R 
Sbjct: 1623 EGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERR- 1681

Query: 333  CASLAQKASETLELK-ERLNMTLGLMRGTILRCTKYNQELYT-------THGLIKGPLSK 384
             A+L Q   E L    ER      +    +L  ++  Q L+T       T   ++  +S+
Sbjct: 1682 -ANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740

Query: 385  VHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTDKLQ---CHITYLEKNLDE 435
            +  E  + +     R  +      + +AA +A+   K Q    H+  ++KN+++
Sbjct: 1741 IQGEMEDIVQE--ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1792



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 35/146 (23%), Positives = 65/146 (44%), Gaps = 14/146 (9%)

Query: 121  QTTEVVHAHARGARLTAARLGRAQHQ-INGRVRQLLRQREVTDHRLSEVRKGLLINQQSV 179
            QT + +      A   A + G+ Q Q +  RVR+L  + E       E  KGL  +++ V
Sbjct: 1792 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRV 1851

Query: 180  KLRGYRPKSE-----KVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTL 234
            K   Y+ + +     ++ D  D + T    ++K+ KR+ E   E+S V L      +  L
Sbjct: 1852 KELTYQTEEDRKNILRLQDLVDKLQT----KVKAYKRQAEEAEEQSNVNLAKFRKLQHEL 1907

Query: 235  NFCFKERLQAVDLMNQPLDKVLEQAR 260
                +E  +  D+    ++K+  ++R
Sbjct: 1908 ----EEAKERADIAESQVNKLRVKSR 1929


>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
          Length = 605

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 65/280 (23%), Positives = 117/280 (41%), Gaps = 44/280 (15%)

Query: 107 ARLPLPLHRKARALQTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLS 166
           +R+   L  +  A++  + +H      +L+ +  G+  +++  ++ +L  + E+ + RLS
Sbjct: 70  SRMLESLSCECEAIKQQQKMHLEKLEEQLSRSH-GQEVNELKTKIEKL--KVELDEARLS 126

Query: 167 EVRKGLLINQQ----SVKLRGYRPKSEKVPDKADS---MLTWEKEELKSMKRKMERDM-- 217
           E +    ++ Q    S K    R  SE+V +   S    L  E  E++SMK  ++ ++  
Sbjct: 127 EKQLKHQVDHQKELLSCKSEELRVMSERVQESMSSEMLALQIELTEMESMKTTLKEEVNE 186

Query: 218 -----EKSEVLLKTLASCRDTLNFCFKER----------LQAVDLMNQPLDKVLEQARRH 262
                E+ E+L+  L    D L    +ER          L+   + NQ L   L+QA   
Sbjct: 187 LQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDLQVQLDQA--- 243

Query: 263 SWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEAKRLLVESKDTLVEMAKNEVDVR 322
               L +A  P ++G            +   A+     +R L+  K     + K  V  R
Sbjct: 244 ----LQQALDPNSKGNSLFAE----VEDRRAAM-----ERQLISMKVKYQSLKKQNVFNR 290

Query: 323 EQQLQISDRVCASLAQKASET-LELKERLNMTLGLMRGTI 361
           EQ  ++  ++   L  K S+T  E +ERL   L    G I
Sbjct: 291 EQMQRMKLQIATLLQMKGSQTEFEQQERLLAMLEQKNGEI 330


>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
          Length = 1194

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 49/230 (21%), Positives = 101/230 (43%), Gaps = 26/230 (11%)

Query: 140 LGRAQH---QINGRVRQLLRQREVTDHRLSEVRKGLLINQ-QSVKLRGYRPKSEKVPDKA 195
           LG+A+    ++   +++ L QRE  + R++ + K  L  Q ++  L     K E      
Sbjct: 277 LGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASK 336

Query: 196 DSMLTWEKEELKSM-------KRKMERDMEKSEVLLK---TLASCRDTLNFC------FK 239
           +S+    +E+ + +       K+K+++ ++K+E L +    LA     LN        F+
Sbjct: 337 ESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFE 396

Query: 240 ERLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNE 299
           ERL+ ++   +  ++ L++AR+   +N            K      +   N    L L E
Sbjct: 397 ERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKL-----LSESNERLQLHLKE 451

Query: 300 AKRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKER 349
               L E K++L E   N   ++++ L   +++ A + +   E  +L+ R
Sbjct: 452 RMGAL-EEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGR 500


>gi|21389505 janus kinase and microtubule interacting protein 1
           isoform 2 [Homo sapiens]
          Length = 626

 Score = 33.5 bits (75), Expect = 0.46
 Identities = 80/365 (21%), Positives = 133/365 (36%), Gaps = 60/365 (16%)

Query: 104 AWYARLPLPLHR-KARALQTTE--VVHAH----ARGARLTAARLGRAQHQIN-------G 149
           A+ + L   LH  K + LQ     ++  H    AR A++    L R Q  +N        
Sbjct: 67  AYISELKAKLHEEKTKELQALREGLIRQHEQEAARTAKIKEGELQRLQATLNVLRDGAAD 126

Query: 150 RVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKSEKV------PDK---ADSMLT 200
           +V+  L      + R +   + L + Q+ ++L+  R ++E+        DK   AD    
Sbjct: 127 KVKTALLTEAREEARRAFDGERLRLQQEILELKAARKQAEEALSNCMQADKTKAADLRAA 186

Query: 201 WE--KEELKSMKRKMERDME--------KSEVLLKTLASCRDTLNFCFKERLQAVDLMNQ 250
           ++  ++E+  +KR+ ERD+         K  V+L              K  LQ  + +++
Sbjct: 187 YQAHQDEVHRIKRECERDIRRLMDEIKGKDRVILALEKELGVQAGQTQKLLLQK-EALDE 245

Query: 251 PLDKVLEQARRHSWVNLSRAP--------------------TPRTQGQKTPPPDPVGTYN 290
            L +V E  R HS       P                      R Q +       +    
Sbjct: 246 QLVQVKEAERHHSSPKRELPPGIGDMVELMGVQDQHMDERDVRRFQLKIAELNSVIRKLE 305

Query: 291 PACALALNEAKRLLVESKDT------LVEMAKNEVDVREQQLQISDRVCASLAQKASETL 344
               L  +E   LL  S++T      LVE  K      E  LQ   R+   +     E +
Sbjct: 306 DRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNEDLLQSIQRMEEKIKNLTRENV 365

Query: 345 ELKERLNMTLGLMRGTILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRH 404
           E+KE+L+    L R T L      ++      L    L + H+     L+R  +   +RH
Sbjct: 366 EMKEKLSAQASLKRHTSLNDLSLTRDEQEIEFLRLQVLEQQHVIDDLSLERERLLRSKRH 425

Query: 405 VGTQL 409
            G  L
Sbjct: 426 RGKSL 430


>gi|150456473 janus kinase and microtubule interacting protein 1
           isoform 1 [Homo sapiens]
          Length = 831

 Score = 33.5 bits (75), Expect = 0.46
 Identities = 80/365 (21%), Positives = 133/365 (36%), Gaps = 60/365 (16%)

Query: 104 AWYARLPLPLHR-KARALQTTE--VVHAH----ARGARLTAARLGRAQHQIN-------G 149
           A+ + L   LH  K + LQ     ++  H    AR A++    L R Q  +N        
Sbjct: 67  AYISELKAKLHEEKTKELQALREGLIRQHEQEAARTAKIKEGELQRLQATLNVLRDGAAD 126

Query: 150 RVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKSEKV------PDK---ADSMLT 200
           +V+  L      + R +   + L + Q+ ++L+  R ++E+        DK   AD    
Sbjct: 127 KVKTALLTEAREEARRAFDGERLRLQQEILELKAARKQAEEALSNCMQADKTKAADLRAA 186

Query: 201 WE--KEELKSMKRKMERDME--------KSEVLLKTLASCRDTLNFCFKERLQAVDLMNQ 250
           ++  ++E+  +KR+ ERD+         K  V+L              K  LQ  + +++
Sbjct: 187 YQAHQDEVHRIKRECERDIRRLMDEIKGKDRVILALEKELGVQAGQTQKLLLQK-EALDE 245

Query: 251 PLDKVLEQARRHSWVNLSRAP--------------------TPRTQGQKTPPPDPVGTYN 290
            L +V E  R HS       P                      R Q +       +    
Sbjct: 246 QLVQVKEAERHHSSPKRELPPGIGDMVELMGVQDQHMDERDVRRFQLKIAELNSVIRKLE 305

Query: 291 PACALALNEAKRLLVESKDT------LVEMAKNEVDVREQQLQISDRVCASLAQKASETL 344
               L  +E   LL  S++T      LVE  K      E  LQ   R+   +     E +
Sbjct: 306 DRNTLLADERNELLKRSRETEVQLKPLVEKNKRMNKKNEDLLQSIQRMEEKIKNLTRENV 365

Query: 345 ELKERLNMTLGLMRGTILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRH 404
           E+KE+L+    L R T L      ++      L    L + H+     L+R  +   +RH
Sbjct: 366 EMKEKLSAQASLKRHTSLNDLSLTRDEQEIEFLRLQVLEQQHVIDDLSLERERLLRSKRH 425

Query: 405 VGTQL 409
            G  L
Sbjct: 426 RGKSL 430


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 33.5 bits (75), Expect = 0.46
 Identities = 42/162 (25%), Positives = 65/162 (40%), Gaps = 19/162 (11%)

Query: 186  PKSEKVPDKADSMLTWEKEE--LKSMKRKMERDME-KSEVLL--------KTLASCRDTL 234
            P+S   P   D  + WE +   LK    + +++ E K EVL         K +   +DT 
Sbjct: 1327 PESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTA 1386

Query: 235  NFCFKERLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACA 294
             +   E L   +   +  DK LEQ  R    +L +  T   Q  K   P          A
Sbjct: 1387 IYQKDEALHVKNEAVKQQDKALEQKGR----DLEQKDTALEQKDKALEPKDKDLEEKDKA 1442

Query: 295  LA----LNEAKRLLVESKDTLVEMAKNEVDVREQQLQISDRV 332
            L     + E K   +E KDT +E     ++ +++ L+  DRV
Sbjct: 1443 LEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRV 1484


>gi|81295809 pericentrin [Homo sapiens]
          Length = 3336

 Score = 33.5 bits (75), Expect = 0.46
 Identities = 34/102 (33%), Positives = 44/102 (43%), Gaps = 10/102 (9%)

Query: 95   LWKGKMKPPAWYARLPLPLHRKARALQTTEVVHAH----ARGARLTAARL----GRAQHQ 146
            L +GK   P   AR P    R   +  T +V   H    ARG RL AA      GRA   
Sbjct: 3225 LAQGKAPRPGPRARQPQSPPRTRESPPTRDVPSGHTRDPARGRRLAAAASPHSGGRATPS 3284

Query: 147  INGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKS 188
             N R+ + L   +  +H L+E    L + QQ  +L G  P S
Sbjct: 3285 PNSRLERSLTASQDPEHSLTEYIHHLEVIQQ--RLGGVLPDS 3324



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 20/140 (14%)

Query: 129 HARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKS 188
           H     LT A L + +      +R++L  R   +  L + R+     Q  ++L   +   
Sbjct: 258 HTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQ-----QHELELLREQHAR 312

Query: 189 EKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLAS--------CRDTL--NFCF 238
           EK     + ++    +E   +K K++ +MEK+  ++KTL          C + L      
Sbjct: 313 EK-----EEVVLRCGQEAAELKEKLQSEMEKNAQIVKTLKEDWESEKDLCLENLRKELSA 367

Query: 239 KERLQAVDLMNQPLDKVLEQ 258
           K + +  DL NQ   ++ EQ
Sbjct: 368 KHQSEMEDLQNQFQKELAEQ 387


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 33.5 bits (75), Expect = 0.46
 Identities = 53/226 (23%), Positives = 94/226 (41%), Gaps = 37/226 (16%)

Query: 133  ARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKSEKVP 192
            AR  ++ LG     + G V  L  QR   + +L ++R+  ++ Q+           +K+ 
Sbjct: 1780 ARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLRE--VLRQRQEGEAAALNTVQKLQ 1837

Query: 193  DKADSMLTWEKEELKSMKRKMER-DMEKSEVLLKTLASCRDTLNFCFKERLQAVDLMNQP 251
            D+   +    +E L S++R + + + EK EV    L   +D +             + + 
Sbjct: 1838 DERRLL----QERLGSLQRALAQLEAEKREVERSALRLEKDRV------------ALRRT 1881

Query: 252  LDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEAKRLLVESKDTL 311
            LDKV  +  R      S   T R   +K      +        L L EA+R + + +  +
Sbjct: 1882 LDKVEREKLR------SHEDTVRLSAEK----GRLDRTLTGAELELAEAQRQIQQLEAQV 1931

Query: 312  VEM------AKNEVDVREQQLQISDRV--CASLAQKASETLELKER 349
            V +      A+ EVD ++QQL++   V    S   +   TLE +ER
Sbjct: 1932 VVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARER 1977


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 33.1 bits (74), Expect = 0.60
 Identities = 60/349 (17%), Positives = 127/349 (36%), Gaps = 47/349 (13%)

Query: 123 TEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLR 182
           TE    H    +   +R+     ++     QL+ Q     + + ++ K +    +    +
Sbjct: 241 TETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKK 300

Query: 183 GYRPKSEKVP--------DKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTL 234
               + EK          +K    L  EKE L+   R   +++EK+   +K L+  +  L
Sbjct: 301 CEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRL 360

Query: 235 NFCFKERLQAVDLMNQPLDKVLEQARRH----SWV----------------NLSRAPTPR 274
           +  ++ +      + + +DK+ E    H     W                  L    T  
Sbjct: 361 HQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKL 420

Query: 275 TQGQKTPP------PDPVGTYNPACALALNEAKRLLVESKDTL---VEMAKNEVDVREQQ 325
           TQ ++          D + TY  +  +  NE    L  +K  L   ++   +++++   +
Sbjct: 421 TQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAK 480

Query: 326 LQISDRVCASLAQKASETLELKERLNMTLGLMRGTILRCTKYNQELYTTHGLIKGPLSKV 385
           ++  + +  +  +   E   L+ ++         T    +KY + +      I+  L KV
Sbjct: 481 IKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKV 540

Query: 386 HLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTDKLQCHITYLEKNLD 434
             +TA++L   L R  Q        E   L +  + L   I  L+K+++
Sbjct: 541 --KTADQLQEQLQRGKQ--------EIENLKEEVESLNSLINDLQKDIE 579


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 14/146 (9%)

Query: 121  QTTEVVHAHARGARLTAARLGRAQHQ-INGRVRQLLRQREVTDHRLSEVRKGLLINQQSV 179
            QT + +      A   A + G+ Q Q +  RVR+L  + E    R +E  KGL  +++ V
Sbjct: 1794 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 1853

Query: 180  KLRGYRPKSE-----KVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTL 234
            K   Y+ + +     ++ D  D +    + ++KS KR+ E   E+S   L      +  L
Sbjct: 1854 KELTYQTEEDRKNILRLQDLVDKL----QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909

Query: 235  NFCFKERLQAVDLMNQPLDKVLEQAR 260
                +E  +  D+    ++K+  ++R
Sbjct: 1910 ----EEAEERADIAESQVNKLRVKSR 1931


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 14/146 (9%)

Query: 121  QTTEVVHAHARGARLTAARLGRAQHQ-INGRVRQLLRQREVTDHRLSEVRKGLLINQQSV 179
            QT + +      A   A + G+ Q Q +  RVR+L  + E    R +E  KGL  +++ V
Sbjct: 1794 QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRV 1853

Query: 180  KLRGYRPKSE-----KVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTL 234
            K   Y+ + +     ++ D  D +    + ++KS KR+ E   E+S   L      +  L
Sbjct: 1854 KELTYQTEEDRKNILRLQDLVDKL----QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909

Query: 235  NFCFKERLQAVDLMNQPLDKVLEQAR 260
                +E  +  D+    ++K+  ++R
Sbjct: 1910 ----EEAEERADIAESQVNKLRVKSR 1931


>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
          Length = 775

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 58/245 (23%), Positives = 109/245 (44%), Gaps = 30/245 (12%)

Query: 133 ARLTAARLGRAQ----HQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKS 188
           ARL   +  RAQ    H +  R  Q L Q E T  +  E+R  L   ++++  R Y  + 
Sbjct: 227 ARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELR--LEETREALAGRAYAAEQ 284

Query: 189 EKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQAVDLM 248
            +  +     LT E EELKS  + +  +  + +  L+ L      L   F+ +LQ  ++ 
Sbjct: 285 MEGFELQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQ-EMR 343

Query: 249 NQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPA---CALALNEAK---- 301
              L +  +Q R+ S V   R      + Q +   + +GTY  A     LA+ + K    
Sbjct: 344 KTALAE--DQLRQQSQVEEQRVAA--LENQISEVSELLGTYEKAKQKDQLAIQKLKERIL 399

Query: 302 RLLVESK------------DTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKER 349
           +L +E+K            D+  E +  +V+V + +++   R+    A+K+  TL++++ 
Sbjct: 400 QLDLENKTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKL 459

Query: 350 LNMTL 354
            ++ +
Sbjct: 460 CDLEI 464


>gi|96974985 coiled-coil and C2 domain containing 1A [Homo sapiens]
          Length = 951

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 253 DKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEA---KRLLVESKD 309
           D VLE   R   V+LS  P P  Q    PP  P     PA A +  E     R L+E+ +
Sbjct: 294 DAVLEALSRGEPVDLSCLPPPPDQLPPDPPSPPSQPPTPATAPSTTEVPPPPRTLLEALE 353

Query: 310 TLVE-------MAKNEVDVREQQL------QISDRVCASLAQKASETLEL 346
             +E        AK++ D R+ ++      Q  D + A  A +A +  EL
Sbjct: 354 QRMERYQVAAAQAKSKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAEL 403


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 11/119 (9%)

Query: 113  LHRKARAL-QTTEVVHAHARGARLTAARLGRAQHQ-INGRVRQLLRQREVTDHRLSEVRK 170
            L R  + L QT   + A    A   A R G+ Q Q +  +VR+L  + +    + +E  K
Sbjct: 1828 LERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALK 1887

Query: 171  GLLINQQSVKLRGYRPKSE-----KVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLL 224
            G+  +++ VK   Y+ + +     ++ D  D +    + ++KS KR+ E   +++   L
Sbjct: 1888 GVRKHERRVKELAYQAEEDRKNLARMQDLVDKL----QSKVKSYKRQFEEAEQQANTNL 1942


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
           (with transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 55/226 (24%), Positives = 97/226 (42%), Gaps = 39/226 (17%)

Query: 156 RQREVTDHRLSEVRKGLLINQQSVKLRGYRPKSEK----VPDKADSMLTWEKEELKSMKR 211
           +++  T+H+ S   + + +N   V+L+  +   +K    VPD        E E LKS   
Sbjct: 637 KEQASTEHQ-SRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQD-ELERLKSQIL 694

Query: 212 KMERDMEKSEVL----LKTLASCRDTLNFCFKERLQAVD-------LMNQPLDKVLEQAR 260
           ++E +  K++ +    L   A     LN   +E  +  D        +++  D++L Q +
Sbjct: 695 ELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVK 754

Query: 261 RHSWVNLSRAPTPR-----TQGQKTPPPDPVGTYNPACA---LALNEAKRLLVE--SKDT 310
             S V   RA   +      + ++    D    Y    A   L   +   L +E  SKD 
Sbjct: 755 ELSMVTELRAQVKQLEMNLAEAERQRRLD----YESQTAHDNLLTEQIHSLSIEAKSKDV 810

Query: 311 LVEMAKNEVDVREQQLQISDR------VCASLAQKASETLELKERL 350
            +E+ +NE+D  + QLQ S++      + + L  K SE LE  ER+
Sbjct: 811 KIEVLQNELD--DVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERV 854



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 35/155 (22%), Positives = 66/155 (42%), Gaps = 11/155 (7%)

Query: 304  LVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTLGLMRGTILR 363
            L+++  T +EM   E D R +QLQ+         ++  E    K+++   L     +   
Sbjct: 1435 LIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKE 1494

Query: 364  CTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTDKLQ 423
              K N+ L     L +G + ++    A+   +  V    +   T L   A L +  DKL 
Sbjct: 1495 ALKENKSLQEELSLARGTIERLTKSLADVESQ--VSAQNKEKDTVLGRLALLQEERDKL- 1551

Query: 424  CHITYLEKNLDELLATHKNLSWGLNCKNIGHEVDG 458
              IT ++++L E      N S   +C+++   ++G
Sbjct: 1552 --ITEMDRSLLE------NQSLSSSCESLKLALEG 1578


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 14/146 (9%)

Query: 121  QTTEVVHAHARGARLTAARLGRAQHQ-INGRVRQLLRQREVTDHRLSEVRKGLLINQQSV 179
            QT + +      A   A + G+ Q Q +  RVR+L  + E    R +E  KGL  +++ V
Sbjct: 1791 QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRV 1850

Query: 180  KLRGYRPKSE-----KVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTL 234
            K   Y+ + +     ++ D  D +    + ++KS KR+ E   E+S   L      +  L
Sbjct: 1851 KELTYQTEEDRKNVLRLQDLVDKL----QAKVKSYKRQAEEAEEQSNANLSKFRKLQHEL 1906

Query: 235  NFCFKERLQAVDLMNQPLDKVLEQAR 260
                +E  +  D+    ++K+  ++R
Sbjct: 1907 ----EEAEERADIAESQVNKLRVKSR 1928


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 17/62 (27%), Positives = 36/62 (58%), Gaps = 2/62 (3%)

Query: 308 KDTLVEM--AKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTLGLMRGTILRCT 365
           +D +VE+   KN++ +R+++++I  +    L  K S+ L+  E L   +GL   T++  T
Sbjct: 459 EDAVVEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLT 518

Query: 366 KY 367
           ++
Sbjct: 519 EF 520


>gi|169208016 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a, 8E isoform 1 [Homo sapiens]
          Length = 594

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 67/329 (20%), Positives = 119/329 (36%), Gaps = 55/329 (16%)

Query: 114 HRKARALQTTEVVHAHARGARLTAARLGRAQHQIN---GRVRQLLRQREVTDHRLSEVRK 170
           H    +  T+  +HA     +  A  L     +I+     ++ L +Q++  +H+L E +K
Sbjct: 52  HLSPHSCSTSSSLHAPQSPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEEKK 111

Query: 171 GLLINQQSVKLRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASC 230
                         R K+E+V +     L  +KEEL +    MER +   E   K LA  
Sbjct: 112 A----------NNERQKAERVLEVQIQTLIIQKEELNTDLYHMERSLRYFEEESKDLA-- 159

Query: 231 RDTLNFCFKERLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYN 290
                   +  LQ    + + L  V+   ++ +                           
Sbjct: 160 -----VRLQHSLQCKGELERALSAVIATEKKKA------------------------NQL 190

Query: 291 PACALALNEAKRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERL 350
            +C+ A  E +         L++    ++    QQLQ+    CA   +        + R 
Sbjct: 191 SSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGE------RARW 244

Query: 351 NMTLGLMRGTILRCTKYNQELYTTHGLIKGPLSKVHLETAEKL--DRPLV--RMYQRHVG 406
           +  +  M   I    K  Q++     L +  LSK+  +TAE L  + P V   +  +H+ 
Sbjct: 245 HQRMSKMSQEICTLKKEKQDMRWVEQL-EWSLSKLKNQTAEPLPPEPPAVPSEVELQHLR 303

Query: 407 TQLPEAARLAQGTDKLQCHITYLEKNLDE 435
            +L   A   Q   K   HI+ L +  +E
Sbjct: 304 KELERVAGELQSQVKNNQHISLLNRRQEE 332


>gi|28269672 serologically defined colon cancer antigen 8 [Homo
           sapiens]
          Length = 713

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 62/276 (22%), Positives = 97/276 (35%), Gaps = 72/276 (26%)

Query: 202 EKEELKSMKRKME--RDMEKSEVLLKTLASCRDTLN--------------FC------FK 239
           E E   S +RKM   R +E  E  + T+     T+N              FC       K
Sbjct: 88  ESEVSPSRRRKMSPLRSLEHEETNMPTMHDLVHTINDQSQYIHHLEAEVKFCKEELSGMK 147

Query: 240 ERLQAVDLMNQPLDKVLEQARR-----------------HSWVNLSRAPTPRTQGQKTPP 282
            ++Q V L N+ L + L+  R+                 +SW+      T    G     
Sbjct: 148 NKIQVVVLENEGLQQQLKSQRQEETLREQTLLDASGNMHNSWIT-----TGEDSGVGETS 202

Query: 283 PDPVGTYNPACALALNEAKRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASE 342
             P    N     A +  ++L +E      E    + ++ E QL+        LA+    
Sbjct: 203 KRPFSHDNADFGKAASAGEQLELEKLKLTYE---EKCEIEESQLKFLRN---DLAEYQRT 256

Query: 343 TLELKERLNM--------TLGLMRGTILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLD 394
             +LKE+L          T   + G  L+C ++   L  TH       + VH++T E+L 
Sbjct: 257 CEDLKEQLKHKEFLLAANTCNRVGGLCLKCAQHEAVLSQTH-------TNVHMQTIERLV 309

Query: 395 R-------PLVRMYQRHVGTQLPEAARLAQGTDKLQ 423
           +        LV +      TQ  EA+   Q    LQ
Sbjct: 310 KERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQ 345


>gi|197313732 pleckstrin homology-like domain, family B, member 2
           isoform a [Homo sapiens]
          Length = 1253

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 27/118 (22%), Positives = 57/118 (48%), Gaps = 10/118 (8%)

Query: 153 QLLRQREVTDH---RLSEVRKGLL--INQQSVKLRGYRPKSEKVPDKADSMLTWEKEELK 207
           +L++++E+ DH   +++E+ K ++    ++ VKL   R K E++ +      T      +
Sbjct: 639 ELMKEKEILDHLNRKIAELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPE 698

Query: 208 SMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQAVD-----LMNQPLDKVLEQAR 260
           SM+ ++++ +++   LL   +   + L F   E    +D     L  Q L +V E  R
Sbjct: 699 SMREQLQQQLKRDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQLLREVAEYQR 756


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,433,980
Number of Sequences: 37866
Number of extensions: 941556
Number of successful extensions: 4202
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 4106
Number of HSP's gapped (non-prelim): 213
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.