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Search of human proteins with 226342978
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226342978 G protein-coupled receptor 85 [Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226342980 G protein-coupled receptor 85 [Homo sapiens] 760 0.0
gi|226342978 G protein-coupled receptor 85 [Homo sapiens] 760 0.0
gi|226342976 G protein-coupled receptor 85 [Homo sapiens] 760 0.0
gi|153266936 G protein-coupled receptor 85 [Homo sapiens] 760 0.0
gi|9507143 G protein-coupled receptor 173 [Homo sapiens] 496 e-140
gi|9506747 G protein-coupled receptor 27 [Homo sapiens] 386 e-107
gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo sa... 90 4e-18
gi|4502607 cholecystokinin A receptor [Homo sapiens] 86 4e-17
gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens] 84 3e-16
gi|28875799 cholecystokinin B receptor [Homo sapiens] 82 6e-16
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 81 2e-15
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 81 2e-15
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 79 5e-15
gi|222080049 5-hydroxytryptamine (serotonin) receptor 2B [Homo s... 79 7e-15
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 77 2e-14
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 77 2e-14
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 77 2e-14
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 76 6e-14
gi|89191861 dopamine receptor D3 isoform a [Homo sapiens] 76 6e-14
gi|5174593 melatonin receptor 1A [Homo sapiens] 76 6e-14
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 75 9e-14
gi|5174595 melatonin receptor 1B [Homo sapiens] 75 1e-13
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 74 3e-13
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 74 3e-13
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 74 3e-13
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 74 3e-13
gi|89191863 dopamine receptor D3 isoform e [Homo sapiens] 74 3e-13
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 73 5e-13
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens] 72 6e-13
gi|4503385 dopamine receptor D2 isoform long [Homo sapiens] 72 6e-13
>gi|226342980 G protein-coupled receptor 85 [Homo sapiens]
Length = 370
Score = 760 bits (1963), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
Sbjct: 1 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
Query: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY
Sbjct: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
Query: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR 180
LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR
Sbjct: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR 180
Query: 181 ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA 240
ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA
Sbjct: 181 ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA 240
Query: 241 ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP 300
ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP
Sbjct: 241 ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP 300
Query: 301 YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS
Sbjct: 301 YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
Query: 361 RLPREPYCVI 370
RLPREPYCVI
Sbjct: 361 RLPREPYCVI 370
>gi|226342978 G protein-coupled receptor 85 [Homo sapiens]
Length = 370
Score = 760 bits (1963), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
Sbjct: 1 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
Query: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY
Sbjct: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
Query: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR 180
LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR
Sbjct: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR 180
Query: 181 ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA 240
ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA
Sbjct: 181 ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA 240
Query: 241 ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP 300
ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP
Sbjct: 241 ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP 300
Query: 301 YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS
Sbjct: 301 YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
Query: 361 RLPREPYCVI 370
RLPREPYCVI
Sbjct: 361 RLPREPYCVI 370
>gi|226342976 G protein-coupled receptor 85 [Homo sapiens]
Length = 370
Score = 760 bits (1963), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
Sbjct: 1 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
Query: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY
Sbjct: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
Query: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR 180
LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR
Sbjct: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR 180
Query: 181 ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA 240
ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA
Sbjct: 181 ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA 240
Query: 241 ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP 300
ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP
Sbjct: 241 ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP 300
Query: 301 YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS
Sbjct: 301 YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
Query: 361 RLPREPYCVI 370
RLPREPYCVI
Sbjct: 361 RLPREPYCVI 370
>gi|153266936 G protein-coupled receptor 85 [Homo sapiens]
Length = 370
Score = 760 bits (1963), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL
Sbjct: 1 MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
Query: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY
Sbjct: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
Query: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR 180
LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR
Sbjct: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFR 180
Query: 181 ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA 240
ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA
Sbjct: 181 ANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAA 240
Query: 241 ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP 300
ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP
Sbjct: 241 ANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGP 300
Query: 301 YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS
Sbjct: 301 YLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
Query: 361 RLPREPYCVI 370
RLPREPYCVI
Sbjct: 361 RLPREPYCVI 370
>gi|9507143 G protein-coupled receptor 173 [Homo sapiens]
Length = 373
Score = 496 bits (1278), Expect = e-140
Identities = 233/374 (62%), Positives = 289/374 (77%), Gaps = 5/374 (1%)
Query: 1 MANYSHAADNILQNLSP--LTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYF 58
MAN + + + LSP +A++KL LG I+ VS+ GN ++S+L++K++ LH+APYYF
Sbjct: 1 MANTTGEPEEVSGALSPPSASAYVKLVLLGLIMCVSLAGNAILSLLVLKERALHKAPYYF 60
Query: 59 LLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVT 118
LLDLC +D +RSA+CFPFV SV++GS+WT+ L+CK++AF+ VL CFH AFMLFCISVT
Sbjct: 61 LLDLCLADGIRSAVCFPFVLASVRHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVT 120
Query: 119 RYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRS 178
RY+AIAHHRFY KR+T WTC AVICM WTLSVAMAFPPV DVGTY FIREEDQC F+HR
Sbjct: 121 RYMAIAHHRFYAKRMTLWTCAAVICMAWTLSVAMAFPPVFDVGTYKFIREEDQCIFEHRY 180
Query: 179 FRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQ 238
F+AND+LGFML+LA+++ AT VY KL+ F + RKMKPVQ V A+SQNWTFHGPGA+GQ
Sbjct: 181 FKANDTLGFMLMLAVLMAATHAVYGKLLLFEYRHRKMKPVQMVPAISQNWTFHGPGATGQ 240
Query: 239 AAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLW 298
AAANW+AGFGRGP PPTLLGIRQN + RRLL +DE K EK++ RMFY +T LFL LW
Sbjct: 241 AAANWIAGFGRGPMPPTLLGIRQNGHAAS-RRLLGMDEVKGEKQLGRMFYAITLLFLLLW 299
Query: 299 GPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFST--TLLY 356
PY+VACYWRVF + VP +L AVWMSFAQA +NP VC N++L++C T
Sbjct: 300 SPYIVACYWRVFVKACAVPHRYLATAVWMSFAQAAVNPIVCFLLNKDLKKCLRTHAPCWG 359
Query: 357 CRKSRLPREPYCVI 370
+ PREPYCV+
Sbjct: 360 TGGAPAPREPYCVM 373
>gi|9506747 G protein-coupled receptor 27 [Homo sapiens]
Length = 375
Score = 386 bits (992), Expect = e-107
Identities = 190/344 (55%), Positives = 241/344 (70%), Gaps = 7/344 (2%)
Query: 22 LKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSV 81
LKL +L ++ VS+ GN+L ++L+V++++LHRAPYY LLDLC +D LR+ C P V +
Sbjct: 20 LKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAA 79
Query: 82 KNGSTWTY---GTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTC 138
+ + G L CK++AFL L CFH AF+L + VTRYLAIAHHRFY +RL W C
Sbjct: 80 RRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPC 139
Query: 139 LAV-ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLA 197
A+ +C W L++A AFPPVLD G E+ C + R A +LGF+LLLA+++ A
Sbjct: 140 AAMLVCAAWALALAAAFPPVLDGGGDD---EDAPCALEQRPDGAPGALGFLLLLAVVVGA 196
Query: 198 TQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLL 257
T LVYL+L+FF+HDRRKM+P + V AVS +WTFHGPGA+GQAAANW AGFGRGPTPP L+
Sbjct: 197 THLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALV 256
Query: 258 GIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVP 317
GIR G RRLLVL+EFK EKR+ +MFY +T LFL LWGPY+VA Y RV R VP
Sbjct: 257 GIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLLLWGPYVVASYLRVLVRPGAVP 316
Query: 318 GGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSR 361
+LTA+VW++FAQAGINP VC NRELR CF C+ R
Sbjct: 317 QAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPR 360
>gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo
sapiens]
Length = 471
Score = 89.7 bits (221), Expect = 4e-18
Identities = 82/331 (24%), Positives = 145/331 (43%), Gaps = 31/331 (9%)
Query: 30 IIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTY 89
+I +++ GN+L+ + + +K L A YFL+ L +D+L + P ++ G W
Sbjct: 84 VIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPL 143
Query: 90 GTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIA----HHRFYTKRLTFWTCLAVICMV 145
+ C V +L VL + L IS+ RY+AI H RF ++ F +A V
Sbjct: 144 PSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIA----V 199
Query: 146 WTLSVAMAFP-PVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLK 204
WT+SV ++ P PV + S + +E C A+D+ F+L+ + + L +
Sbjct: 200 WTISVGISMPIPVFGLQDDSKVFKEGSCLL------ADDN--FVLIGSFVSFFIPLTIMV 251
Query: 205 LIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGI-RQNA 263
+ +F+ + K + VS T + A+ ++L I R+
Sbjct: 252 ITYFLTIKSLQK--EATLCVSDLGT-----RAKLASFSFLPQSSLSSEKLFQRSIHREPG 304
Query: 264 NTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFAR---GPVVPGGF 320
+ TGRR + E++ ++ I+ FLF+ +W P+ + V + V G
Sbjct: 305 SYTGRR---TMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGAL 361
Query: 321 LTAAVWMSFAQAGINPFVCIFSNRELRRCFS 351
L VW+ + + +NP V N+ R FS
Sbjct: 362 LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFS 392
>gi|4502607 cholecystokinin A receptor [Homo sapiens]
Length = 428
Score = 86.3 bits (212), Expect = 4e-17
Identities = 82/347 (23%), Positives = 141/347 (40%), Gaps = 18/347 (5%)
Query: 24 LTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPF--VFNSV 81
L SL F++ SV+GN L+ +L+++K + FLL L SD++ C PF + N +
Sbjct: 47 LYSLIFLL--SVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLL 104
Query: 82 KNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAV 141
K+ + +G+ CK + S + F L IS+ RY AI T L V
Sbjct: 105 KD---FIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKV 161
Query: 142 ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSL--GFMLLLALILLATQ 199
I W LS + P + F + +Q R ND + + L LIL
Sbjct: 162 IAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIP 221
Query: 200 LVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAG-FGRGPTPPTLLG 258
+ + + + + + ++F A+ ++ P + G + + PP L
Sbjct: 222 GIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLE 281
Query: 259 IRQNANTTGRRRLLVLD-----EFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARG 313
+RQ + + R + +KR+ RM ++ LF W P A WR +
Sbjct: 282 LRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTA 341
Query: 314 PV---VPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYC 357
+ G ++ + +S+ + +NP + F N+ R F T C
Sbjct: 342 SAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCC 388
>gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens]
Length = 357
Score = 83.6 bits (205), Expect = 3e-16
Identities = 75/354 (21%), Positives = 144/354 (40%), Gaps = 31/354 (8%)
Query: 3 NYSHAADNILQNLSPLTAF--LKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLL 60
N+S D++ + L+ F L LT LGF++ + NLL+ +++ +T HR P+ +
Sbjct: 21 NHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVA 80
Query: 61 DLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRY 120
+ SD+L +A+ P +G W G C++ VL C + + + I++ RY
Sbjct: 81 SMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRY 140
Query: 121 LAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHR-SF 179
+I H YT R +I + W LS ++ P+L ++ ++C S+
Sbjct: 141 WSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSY 200
Query: 180 RANDSLG-FMLLLALILLATQLVYLKLIFFVHDRR--KMKPVQFVAAVSQNWTFHGPGAS 236
++G F L L ++L +Y F V R+ + P+ V +
Sbjct: 201 AVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDS--------- 251
Query: 237 GQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLT 296
P ++ ++A T + E K E+R + M I+ +F+
Sbjct: 252 --------------AKQPQMVFTVRHATVTFQPEGDTWREQK-EQRAALMVGILIGVFVL 296
Query: 297 LWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCF 350
W P+ + +P + + +W+ ++ + NP + N+ F
Sbjct: 297 CWIPFFLTELISPLCSCD-IPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAF 349
>gi|28875799 cholecystokinin B receptor [Homo sapiens]
Length = 447
Score = 82.4 bits (202), Expect = 6e-16
Identities = 95/366 (25%), Positives = 140/366 (38%), Gaps = 29/366 (7%)
Query: 22 LKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSV 81
+++T I +SV GN+LI ++L + L FLL L SD+L + C PF
Sbjct: 56 IRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPN 115
Query: 82 KNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAV 141
G T+ +GT+ CK +++L +S + L I++ RY AI T V
Sbjct: 116 LMG-TFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARV 174
Query: 142 ICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALIL------ 195
I W LS + P + QC + S R + +LLL L
Sbjct: 175 IVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVM 234
Query: 196 -----LATQLVYLKLIF-----FVHDRRKMKPVQFVAAVSQNWTFH-GPGASGQAAANWL 244
L ++ +YL L F R AV QN GA G+ +
Sbjct: 235 AVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCY 294
Query: 245 AGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVA 304
R L + +G R + +KR+ RM ++ LF W P A
Sbjct: 295 VQLPRSRPALELTALTAPGPGSGSRPTQA--KLLAKKRVVRMLLVIVVLFFLCWLPVYSA 352
Query: 305 CYWRVFARGP----VVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
WR F GP + G ++ +S+A A +NP V F +R R+ T C
Sbjct: 353 NTWRAF-DGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARC--- 408
Query: 361 RLPREP 366
PR P
Sbjct: 409 -CPRPP 413
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 80.9 bits (198), Expect = 2e-15
Identities = 76/360 (21%), Positives = 148/360 (41%), Gaps = 34/360 (9%)
Query: 2 ANYSHAADNILQNLSPLTAFLKLTSLGFIIGV----SVVGNLLISILLVKDKTLHRAPYY 57
AN++ + P + S+G ++G ++VGN+L+ + + ++ L Y
Sbjct: 23 ANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNY 82
Query: 58 FLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISV 117
F+++L +D+L S PF +++ W G + C + A + VL C + L IS+
Sbjct: 83 FIVNLAMADLLLSFTVLPFSA-ALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISI 141
Query: 118 TRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHR 177
RY+ + + Y +T + + VW LS ++ P+L ++ +C
Sbjct: 142 DRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLG-WKEPAPNDDKECGVTEE 200
Query: 178 SFRA-NDSLG-FMLLLALILLATQLVYLKLIFFVHD-----RRKMKPVQFVAAVSQNWTF 230
F A SLG F + LA+IL+ VY+ + ++M + + + F
Sbjct: 201 PFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNF 260
Query: 231 HGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIM 290
H S A +G P + + ++ L +F EK+ ++ I+
Sbjct: 261 HEDTLSSTKA--------KGHNPRSSIAVK-------------LFKFSREKKAAKTLGIV 299
Query: 291 TFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCF 350
+F+ W P+ +A P W+ + + +NP + S++E +R F
Sbjct: 300 VGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAF 359
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 80.9 bits (198), Expect = 2e-15
Identities = 85/354 (24%), Positives = 150/354 (42%), Gaps = 44/354 (12%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGST 86
L I ++V GNLL+ + + ++ L YF+++L +D+L SA PF G
Sbjct: 103 LAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGF- 161
Query: 87 WTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVW 146
W +G C V A + VL C + L ISV RY+ + H Y +T A++ ++W
Sbjct: 162 WAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLW 221
Query: 147 TLSVAMAFPPVLDVGTYSFIREEDQ-CTFQHRSFRA--NDSLGFMLLLALILLATQLVYL 203
+++ ++ P+L G + +++ C + A + F L +A+I++ VY+
Sbjct: 222 VVALVVSVGPLL--GWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYV 279
Query: 204 ------KLIFFVHDRRKMKPVQFVAAVSQNWTFHG-PGASGQAAANWLAGFGRGPTPPTL 256
+ + R + K + V + G GA G +A +G T +
Sbjct: 280 VARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSA-------KGHTFRSS 332
Query: 257 LGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVV 316
L +R L +F EK+ ++ I+ +F+ W P+ V G +
Sbjct: 333 LSVR-------------LLKFSREKKAAKTLAIVVGVFVLCWFPFFF-----VLPLGSLF 374
Query: 317 P-----GGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTL-LYCRKSRLPR 364
P G W+ + + +NP + S+RE +R F L CR+ R R
Sbjct: 375 PQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRR 428
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 79.3 bits (194), Expect = 5e-15
Identities = 73/338 (21%), Positives = 137/338 (40%), Gaps = 9/338 (2%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGST 86
+ I+ + V GN+L+ + + K L F++ L +D++ + PF V G
Sbjct: 65 MALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGR- 123
Query: 87 WTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVW 146
W YG+ C++ + VL + L I++ RYLAI Y LT ++C VW
Sbjct: 124 WEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVW 183
Query: 147 TLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLI 206
+S ++F P+L + E +C + + + + +++ L + +
Sbjct: 184 AISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFV 243
Query: 207 FFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNA--- 263
+ R K V+ + + + + GP + + + P PP A
Sbjct: 244 YLRVFREAQKQVKKIDSCERRF-LGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAPLA 302
Query: 264 -NTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLT 322
G+RR L + +K + + IM +F W P+ +A + F R +VP
Sbjct: 303 NGRAGKRRPSRLVALREQKALKTLGIIMG-VFTLCWLPFFLANVVKAFHR-ELVPDRLFV 360
Query: 323 AAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKS 360
W+ +A + NP + S + R+ F L R++
Sbjct: 361 FFNWLGYANSAFNPIIYCRS-PDFRKAFQGLLCCARRA 397
>gi|222080049 5-hydroxytryptamine (serotonin) receptor 2B [Homo
sapiens]
Length = 481
Score = 79.0 bits (193), Expect = 7e-15
Identities = 81/337 (24%), Positives = 138/337 (40%), Gaps = 25/337 (7%)
Query: 30 IIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTY 89
+I ++ GN L+ + + +K L A YFL+ L +D+L P ++ + W
Sbjct: 64 VIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAMWPL 123
Query: 90 GTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLS 149
+ C FL VL + L ISV RY+AI + + T I +VW +S
Sbjct: 124 PLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLIS 183
Query: 150 VAMAFP-PVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFF 208
+ +A P P+ + T C F FML +L T L + + +F
Sbjct: 184 IGIAIPVPIKGIETDVDNPNNITCVLTKERFG-----DFMLFGSLAAFFTPLAIMIVTYF 238
Query: 209 --VHDRRKM------KPVQFVAAVSQNWTF---HGPGASGQAAANWLAGFGRGPTPPTL- 256
+H +K KP Q + ++ + F P +S + A L G + P
Sbjct: 239 LTIHALQKKAYLVKNKPPQRLTWLTVSTVFQRDETPCSSPEKVA-MLDGSRKDKALPNSG 297
Query: 257 -LGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVF--ARG 313
+ + +T G++ + + E+R S++ I+ FLFL +W P+ + V +
Sbjct: 298 DETLMRRTSTIGKKSVQTISN---EQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCN 354
Query: 314 PVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCF 350
L VW+ + +G+NP V N+ R F
Sbjct: 355 QTTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAF 391
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 77.4 bits (189), Expect = 2e-14
Identities = 78/354 (22%), Positives = 137/354 (38%), Gaps = 47/354 (13%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGST 86
L I +++ GN L+ I + K L + Y ++ L +D+ + PFV + G
Sbjct: 88 LTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGK 147
Query: 87 WTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVW 146
W +G C V + V+ C + L IS+ RYL I Y R +I VW
Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207
Query: 147 TLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLI 206
LS ++ PP+ G + ++ C + G+ + + + + +
Sbjct: 208 LLSASITLPPLF--GWAQNVNDDKVCLI-------SQDFGYTIYSTAVAFYIPMSVMLFM 258
Query: 207 FFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGI------- 259
++ Q A A AA + GF R P +++ +
Sbjct: 259 YY----------QIYKA-----------ARKSAAKHKFPGFPR-VEPDSVIALNGIVKLQ 296
Query: 260 RQNANTTGRRRLLV-----LDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARG- 313
++ RLL + FK E++ + I+ F W P+ + R F G
Sbjct: 297 KEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT 356
Query: 314 --PVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPRE 365
+P +W+ +A + INPF+ F NR+LR + +LL C+ + R+
Sbjct: 357 SCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTY-RSLLQCQYRNINRK 409
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 77.4 bits (189), Expect = 2e-14
Identities = 78/354 (22%), Positives = 137/354 (38%), Gaps = 47/354 (13%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGST 86
L I +++ GN L+ I + K L + Y ++ L +D+ + PFV + G
Sbjct: 88 LTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGK 147
Query: 87 WTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVW 146
W +G C V + V+ C + L IS+ RYL I Y R +I VW
Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207
Query: 147 TLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLI 206
LS ++ PP+ G + ++ C + G+ + + + + +
Sbjct: 208 LLSASITLPPLF--GWAQNVNDDKVCLI-------SQDFGYTIYSTAVAFYIPMSVMLFM 258
Query: 207 FFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGI------- 259
++ Q A A AA + GF R P +++ +
Sbjct: 259 YY----------QIYKA-----------ARKSAAKHKFPGFPR-VEPDSVIALNGIVKLQ 296
Query: 260 RQNANTTGRRRLLV-----LDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARG- 313
++ RLL + FK E++ + I+ F W P+ + R F G
Sbjct: 297 KEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT 356
Query: 314 --PVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPRE 365
+P +W+ +A + INPF+ F NR+LR + +LL C+ + R+
Sbjct: 357 SCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTY-RSLLQCQYRNINRK 409
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 77.4 bits (189), Expect = 2e-14
Identities = 78/354 (22%), Positives = 137/354 (38%), Gaps = 47/354 (13%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGST 86
L I +++ GN L+ I + K L + Y ++ L +D+ + PFV + G
Sbjct: 88 LTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGK 147
Query: 87 WTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVW 146
W +G C V + V+ C + L IS+ RYL I Y R +I VW
Sbjct: 148 WIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVW 207
Query: 147 TLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLI 206
LS ++ PP+ G + ++ C + G+ + + + + +
Sbjct: 208 LLSASITLPPLF--GWAQNVNDDKVCLI-------SQDFGYTIYSTAVAFYIPMSVMLFM 258
Query: 207 FFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGI------- 259
++ Q A A AA + GF R P +++ +
Sbjct: 259 YY----------QIYKA-----------ARKSAAKHKFPGFPR-VEPDSVIALNGIVKLQ 296
Query: 260 RQNANTTGRRRLLV-----LDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARG- 313
++ RLL + FK E++ + I+ F W P+ + R F G
Sbjct: 297 KEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGT 356
Query: 314 --PVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPRE 365
+P +W+ +A + INPF+ F NR+LR + +LL C+ + R+
Sbjct: 357 SCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTY-RSLLQCQYRNINRK 409
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 75.9 bits (185), Expect = 6e-14
Identities = 90/362 (24%), Positives = 142/362 (39%), Gaps = 36/362 (9%)
Query: 17 PLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPF 76
P A L L + +V GNLL+ + + L F+ L +D++ + P
Sbjct: 34 PWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPP 93
Query: 77 VFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFW 136
G W G C++ + VL + L ++V RYLA+ + Y +T
Sbjct: 94 AATLALTGH-WPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKR 152
Query: 137 TCLAVICMVWTLSVAMAFPPVLD----VGTYSFIREEDQCTFQHRSFRANDSLGFMLLLA 192
+ +VW +S A++F P++ VG + E +C R ++ ++LL +
Sbjct: 153 CARTAVVLVWVVSAAVSFAPIMSQWWRVGADA---EAQRCHSNPRCCAFASNMPYVLLSS 209
Query: 193 LILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHG------PGASGQAAANWLAG 246
+ L+ ++ FV+ R FV A Q G P S A + LA
Sbjct: 210 SVSFYLPLL---VMLFVYAR------VFVVATRQLRLLRGELGRFPPEESPPAPSRSLA- 259
Query: 247 FGRGPTPPTLLGIRQNANTTGRR--RLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVA 304
P P + GRR RLL L E + + + IM F W P+ +A
Sbjct: 260 ----PAPVGTCAPPEGVPACGRRPARLLPLRE---HRALCTLGLIMG-TFTLCWLPFFLA 311
Query: 305 CYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPR 364
R +VPG A W+ +A + NP + S + R F L C + RLP
Sbjct: 312 NVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRS-PDFRSAFRRLLCRCGR-RLPP 369
Query: 365 EP 366
EP
Sbjct: 370 EP 371
>gi|89191861 dopamine receptor D3 isoform a [Homo sapiens]
Length = 400
Score = 75.9 bits (185), Expect = 6e-14
Identities = 77/372 (20%), Positives = 143/372 (38%), Gaps = 48/372 (12%)
Query: 20 AFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFN 79
A+ L+ I+ + V GN L+ + ++K++ L Y ++ L +D+L + + P+V
Sbjct: 30 AYYALSYCALILAI-VFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVY 88
Query: 80 SVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAI---AHHRFYTKRLTFW 136
G W + + C V L V+ C + L IS+ RY A+ H++ T + +
Sbjct: 89 LEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCR 148
Query: 137 TCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILL 196
+I VW L+ A++ P + T + C+ + F S ++ L
Sbjct: 149 RVALMITAVWVLAFAVSCPLLFGFNTTG---DPTVCSISNPDFVIYSS---VVSFYLPFG 202
Query: 197 ATQLVYLKLIFFVHDRRKMK----------------PVQFVA------------AVSQNW 228
T LVY ++ + RR+ + P Q ++ ++ Q+
Sbjct: 203 VTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDT 262
Query: 229 TFHGPG---ASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGR-RRLLVLDEFK------ 278
GPG G+ PT L + + GR L L +
Sbjct: 263 ALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPL 322
Query: 279 MEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFV 338
EK+ ++M I+ F+ W P+ + + V +A W+ + + +NP +
Sbjct: 323 REKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVI 382
Query: 339 CIFSNRELRRCF 350
N E R+ F
Sbjct: 383 YTTFNIEFRKAF 394
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 75.9 bits (185), Expect = 6e-14
Identities = 53/190 (27%), Positives = 90/190 (47%), Gaps = 3/190 (1%)
Query: 29 FIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWT 88
F I V ++GNLL+ + + ++K L A F++ L +D++ + +P V S+ N W
Sbjct: 36 FTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNG-WN 94
Query: 89 YGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTL 148
G L C+V FL LS + F + I++ RY I H Y K + L + ++W L
Sbjct: 95 LGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLL 154
Query: 149 SVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKL-IF 207
++A A P L GT + CTF A + + ++ YL++ I
Sbjct: 155 TLA-AVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWIL 213
Query: 208 FVHDRRKMKP 217
+ R+++KP
Sbjct: 214 VLQVRQRVKP 223
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 75.1 bits (183), Expect = 9e-14
Identities = 82/390 (21%), Positives = 148/390 (37%), Gaps = 67/390 (17%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFV-FNSVKNGS 85
LG +I +V+GN + + +++L Y + L +D++ S + P V N
Sbjct: 43 LGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLN-- 100
Query: 86 TWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMV 145
WT G +TC + L VL C + L I++ RY AI Y + T A+I +
Sbjct: 101 KWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLT 160
Query: 146 WTLSVAMAFPPVLDVGTYSFIREEDQCTF-QHRSFRANDSLG-FMLLLALILLATQLVYL 203
W + ++ PP+L T + D CT + + + G F + L L+L+ ++
Sbjct: 161 WLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFR 220
Query: 204 KLIFFVHDRRKMKPVQFVAAVSQNWTFHGP-------GASGQAAANWLAGF--------- 247
F + R+ +K V+ A +++ P G SG + NW G
Sbjct: 221 AARFRI--RKTVKKVEKTGADTRHGASPAPQPKKSVNGESG--SRNWRLGVESKAGGALC 276
Query: 248 ---------------------------------GRGPTP--PTLLGIRQNANTTGRRRLL 272
GPTP P + N +R++
Sbjct: 277 ANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMA 336
Query: 273 VLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAV-WMSFAQ 331
+ E K K + I+ F+ W P+ + F L A + W+ ++
Sbjct: 337 LARERKTVKTLG----IIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSN 392
Query: 332 AGINPFVCIFSNRELRRCFSTTL--LYCRK 359
+ +NP + + N++ + F + +CR+
Sbjct: 393 SLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 422
>gi|5174595 melatonin receptor 1B [Homo sapiens]
Length = 362
Score = 74.7 bits (182), Expect = 1e-13
Identities = 50/186 (26%), Positives = 87/186 (46%), Gaps = 3/186 (1%)
Query: 33 VSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTL 92
V VVGNLL+ + +++++ L A FL+ L +D++ + +P + ++ W G
Sbjct: 53 VDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDG-WALGEE 111
Query: 93 TCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAM 152
CK AF+ LS + F + I++ RY I H Y + W IC++W L+V +
Sbjct: 112 HCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTV-V 170
Query: 153 AFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKL-IFFVHD 211
A P VG+ + CTF + + ++ L + YL++ + +
Sbjct: 171 ALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQA 230
Query: 212 RRKMKP 217
RRK KP
Sbjct: 231 RRKAKP 236
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 73.6 bits (179), Expect = 3e-13
Identities = 82/351 (23%), Positives = 146/351 (41%), Gaps = 52/351 (14%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPF--VFNSVKNG 84
LG +I V+GN+L+ + + + LH +Y++++L +D+L ++ PF +F +
Sbjct: 33 LGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVL--- 89
Query: 85 STWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICM 144
W +G + C + A + VL C + L IS+ RY+ +++ Y +T L +
Sbjct: 90 GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLC 149
Query: 145 VWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLAL----ILLATQL 200
VW LS+ ++ P+ + ED+ Q N+ G++L AL + LA L
Sbjct: 150 VWALSLVISIGPLFG---WRQPAPEDETICQ-----INEEPGYVLFSALGSFYLPLAIIL 201
Query: 201 VYLKLIFFVHDR--RKMKP-VQFVAAVSQNWTFH------GPGASGQAAANWLAGFGRGP 251
V ++ V R R +K ++ + S+ T G SG A+A F
Sbjct: 202 VMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFS--- 258
Query: 252 TPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFA 311
RLL +F EK+ ++ I+ F+ W P+ + F
Sbjct: 259 -----------------VRLL---KFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFF 298
Query: 312 RGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTL---LYCRK 359
W+ + + INP + S++E ++ F L CRK
Sbjct: 299 PDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 73.6 bits (179), Expect = 3e-13
Identities = 82/351 (23%), Positives = 146/351 (41%), Gaps = 52/351 (14%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPF--VFNSVKNG 84
LG +I V+GN+L+ + + + LH +Y++++L +D+L ++ PF +F +
Sbjct: 33 LGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVL--- 89
Query: 85 STWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICM 144
W +G + C + A + VL C + L IS+ RY+ +++ Y +T L +
Sbjct: 90 GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLC 149
Query: 145 VWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLAL----ILLATQL 200
VW LS+ ++ P+ + ED+ Q N+ G++L AL + LA L
Sbjct: 150 VWALSLVISIGPLFG---WRQPAPEDETICQ-----INEEPGYVLFSALGSFYLPLAIIL 201
Query: 201 VYLKLIFFVHDR--RKMKP-VQFVAAVSQNWTFH------GPGASGQAAANWLAGFGRGP 251
V ++ V R R +K ++ + S+ T G SG A+A F
Sbjct: 202 VMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFS--- 258
Query: 252 TPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFA 311
RLL +F EK+ ++ I+ F+ W P+ + F
Sbjct: 259 -----------------VRLL---KFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFF 298
Query: 312 RGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTL---LYCRK 359
W+ + + INP + S++E ++ F L CRK
Sbjct: 299 PDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 73.6 bits (179), Expect = 3e-13
Identities = 82/351 (23%), Positives = 146/351 (41%), Gaps = 52/351 (14%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPF--VFNSVKNG 84
LG +I V+GN+L+ + + + LH +Y++++L +D+L ++ PF +F +
Sbjct: 33 LGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVL--- 89
Query: 85 STWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICM 144
W +G + C + A + VL C + L IS+ RY+ +++ Y +T L +
Sbjct: 90 GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLC 149
Query: 145 VWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLAL----ILLATQL 200
VW LS+ ++ P+ + ED+ Q N+ G++L AL + LA L
Sbjct: 150 VWALSLVISIGPLFG---WRQPAPEDETICQ-----INEEPGYVLFSALGSFYLPLAIIL 201
Query: 201 VYLKLIFFVHDR--RKMKP-VQFVAAVSQNWTFH------GPGASGQAAANWLAGFGRGP 251
V ++ V R R +K ++ + S+ T G SG A+A F
Sbjct: 202 VMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFS--- 258
Query: 252 TPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFA 311
RLL +F EK+ ++ I+ F+ W P+ + F
Sbjct: 259 -----------------VRLL---KFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFF 298
Query: 312 RGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTL---LYCRK 359
W+ + + INP + S++E ++ F L CRK
Sbjct: 299 PDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 73.6 bits (179), Expect = 3e-13
Identities = 82/351 (23%), Positives = 146/351 (41%), Gaps = 52/351 (14%)
Query: 27 LGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPF--VFNSVKNG 84
LG +I V+GN+L+ + + + LH +Y++++L +D+L ++ PF +F +
Sbjct: 33 LGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVL--- 89
Query: 85 STWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICM 144
W +G + C + A + VL C + L IS+ RY+ +++ Y +T L +
Sbjct: 90 GYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLC 149
Query: 145 VWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLAL----ILLATQL 200
VW LS+ ++ P+ + ED+ Q N+ G++L AL + LA L
Sbjct: 150 VWALSLVISIGPLFG---WRQPAPEDETICQ-----INEEPGYVLFSALGSFYLPLAIIL 201
Query: 201 VYLKLIFFVHDR--RKMKP-VQFVAAVSQNWTFH------GPGASGQAAANWLAGFGRGP 251
V ++ V R R +K ++ + S+ T G SG A+A F
Sbjct: 202 VMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFS--- 258
Query: 252 TPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFA 311
RLL +F EK+ ++ I+ F+ W P+ + F
Sbjct: 259 -----------------VRLL---KFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFF 298
Query: 312 RGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTL---LYCRK 359
W+ + + INP + S++E ++ F L CRK
Sbjct: 299 PDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRK 349
>gi|89191863 dopamine receptor D3 isoform e [Homo sapiens]
Length = 367
Score = 73.6 bits (179), Expect = 3e-13
Identities = 73/362 (20%), Positives = 140/362 (38%), Gaps = 61/362 (16%)
Query: 20 AFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFN 79
A+ L+ I+ + V GN L+ + ++K++ L Y ++ L +D+L + + P+V
Sbjct: 30 AYYALSYCALILAI-VFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVY 88
Query: 80 SVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAI---AHHRFYTKRLTFW 136
G W + + C V L V+ C + L IS+ RY A+ H++ T + +
Sbjct: 89 LEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCR 148
Query: 137 TCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILL 196
+I VW L+ A++ P + T + C+ + F S ++ L
Sbjct: 149 RVALMITAVWVLAFAVSCPLLFGFNTTG---DPTVCSISNPDFVIYSS---VVSFYLPFG 202
Query: 197 ATQLVYLKLIFFVHDRRKMK----------------PVQFVA------------AVSQNW 228
T LVY ++ + RR+ + P Q ++ ++ Q+
Sbjct: 203 VTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDT 262
Query: 229 TFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFY 288
GPG + +++ T R L+ L EK+ ++M
Sbjct: 263 ALGGPGFQERGGE-----------------LKREEKT--RNSLMPL----REKKATQMVA 299
Query: 289 IMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRR 348
I+ F+ W P+ + + V +A W+ + + +NP + N E R+
Sbjct: 300 IVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRK 359
Query: 349 CF 350
F
Sbjct: 360 AF 361
>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
Length = 430
Score = 72.8 bits (177), Expect = 5e-13
Identities = 84/349 (24%), Positives = 139/349 (39%), Gaps = 56/349 (16%)
Query: 13 QNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAI 72
Q+ SP+ A + + I + +VGN L+ +++K++ +H F+L+L SD+L
Sbjct: 37 QHTSPVAAMF-IVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIF 95
Query: 73 CFPFVFNSVKNGST-WTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTK 131
C P V N T W + TCK+ + +S + F L I+V R+ I H + +
Sbjct: 96 CMPTTL--VDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHP--FRE 151
Query: 132 RLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRS--------FRAND 183
+LT L I ++W L++ + P + T + REE R+ + A
Sbjct: 152 KLTLRKALVTIAVIWALALLIMCPSAV---TLTVTREEHHFMVDARNRSYPLYSCWEAWP 208
Query: 184 SLGFMLLLALILLA-TQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAAN 242
G + +L + L L LI ++ R K Q GP G+ AA+
Sbjct: 209 EKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQ----------APGPAPGGEEAAD 258
Query: 243 WLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYL 302
A RRR V+ M + T +L LW L
Sbjct: 259 PRA---------------------SRRRARVVHMLVM------VALFFTLSWLPLWALLL 291
Query: 303 VACYWRVFA-RGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCF 350
+ Y ++ A + +V A W++F + NP + + N RR F
Sbjct: 292 LIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGF 340
>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
Length = 414
Score = 72.4 bits (176), Expect = 6e-13
Identities = 49/191 (25%), Positives = 90/191 (47%), Gaps = 9/191 (4%)
Query: 25 TSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNG 84
T L +I V V GN+L+ + + ++K L Y ++ L +D+L + + P+V G
Sbjct: 39 TLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVG 98
Query: 85 STWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAV-IC 143
W + + C + L V+ C + L IS+ RY A+A Y R + + V I
Sbjct: 99 E-WKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIS 157
Query: 144 MVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYL 203
+VW LS ++ P + + ++++C + +F S+ + + + T LVY+
Sbjct: 158 IVWVLSFTISCPLLFGLNN----ADQNECIIANPAFVVYSSI---VSFYVPFIVTLLVYI 210
Query: 204 KLIFFVHDRRK 214
K+ + RRK
Sbjct: 211 KIYIVLRRRRK 221
Score = 38.1 bits (87), Expect = 0.013
Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 260 RQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGG 319
R + T RR+L + EK+ ++M I+ +F+ W P+ + + + P
Sbjct: 323 RTSLKTMSRRKL----SQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVL 378
Query: 320 FLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYC 357
+ +A W+ + + +NP + N E R+ F +L+C
Sbjct: 379 Y-SAFTWLGYVNSAVNPIIYTTFNIEFRKAF-LKILHC 414
>gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]
Length = 443
Score = 72.4 bits (176), Expect = 6e-13
Identities = 49/191 (25%), Positives = 90/191 (47%), Gaps = 9/191 (4%)
Query: 25 TSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNG 84
T L +I V V GN+L+ + + ++K L Y ++ L +D+L + + P+V G
Sbjct: 39 TLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVG 98
Query: 85 STWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAV-IC 143
W + + C + L V+ C + L IS+ RY A+A Y R + + V I
Sbjct: 99 E-WKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIS 157
Query: 144 MVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYL 203
+VW LS ++ P + + ++++C + +F S+ + + + T LVY+
Sbjct: 158 IVWVLSFTISCPLLFGLNN----ADQNECIIANPAFVVYSSI---VSFYVPFIVTLLVYI 210
Query: 204 KLIFFVHDRRK 214
K+ + RRK
Sbjct: 211 KIYIVLRRRRK 221
Score = 38.1 bits (87), Expect = 0.013
Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 260 RQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGG 319
R + T RR+L + EK+ ++M I+ +F+ W P+ + + + P
Sbjct: 352 RTSLKTMSRRKL----SQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVL 407
Query: 320 FLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYC 357
+ +A W+ + + +NP + N E R+ F +L+C
Sbjct: 408 Y-SAFTWLGYVNSAVNPIIYTTFNIEFRKAF-LKILHC 443
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.333 0.142 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,081,010
Number of Sequences: 37866
Number of extensions: 590366
Number of successful extensions: 2929
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 481
Number of HSP's successfully gapped in prelim test: 231
Number of HSP's that attempted gapping in prelim test: 1739
Number of HSP's gapped (non-prelim): 951
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.