Search of human proteins with 226246540

Search of human proteins with 226246540

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226246540 zinc finger, MYND-type containing 12 isoform 2
[Homo sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226246540 zinc finger, MYND-type containing 12 isoform 2 [Hom...   506   e-144
gi|226246519 zinc finger, MYND-type containing 12 isoform 1 [Hom...   449   e-126
gi|156938257 leucine rich repeat containing 16B [Homo sapiens]         33   0.24 
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]          32   0.54 
gi|38570062 hypothetical protein LOC51608 [Homo sapiens]               30   1.6  
gi|45243501 BCL2-like 13 (apoptosis facilitator) [Homo sapiens]        30   2.0  
gi|18104962 amyloid beta precursor protein-binding protein 2 [Ho...    30   2.7  
gi|156523253 RWD domain containing 2A [Homo sapiens]                   30   2.7  
gi|34304360 nephrocystin 3 [Homo sapiens]                              29   4.6  
gi|155722985 SMC5 protein [Homo sapiens]                               29   4.6  
gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]              28   5.9  
gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens]               28   5.9  
gi|21389483 leucine-rich repeats and guanylate kinase domain con...    28   5.9  
gi|45237195 Janus kinase and microtubule interacting protein 2 [...    28   7.8  
gi|38201680 meiotic recombination protein SPO11 isoform b [Homo ...    28   7.8  
gi|46358428 selective LIM binding factor homolog [Homo sapiens]        28   7.8  
gi|133922609 hypothetical protein LOC23383 [Homo sapiens]              28   7.8  

>gi|226246540 zinc finger, MYND-type containing 12 isoform 2 [Homo
           sapiens]
          Length = 255

 Score =  506 bits (1303), Expect = e-144
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MSALDSTAHFHALLQFRGRTAAWPAAAAAAAGLGRIVQAEEYLFQAQWTVLKSTDCSNAT 60
           MSALDSTAHFHALLQFRGRTAAWPAAAAAAAGLGRIVQAEEYLFQAQWTVLKSTDCSNAT
Sbjct: 1   MSALDSTAHFHALLQFRGRTAAWPAAAAAAAGLGRIVQAEEYLFQAQWTVLKSTDCSNAT 60

Query: 61  HSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKL 120
           HSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKL
Sbjct: 61  HSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKL 120

Query: 121 DLADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTS 180
           DLADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTS
Sbjct: 121 DLADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTS 180

Query: 181 ILNIRESTSDKAPQKTIFVLKILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTI 240
           ILNIRESTSDKAPQKTIFVLKILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTI
Sbjct: 181 ILNIRESTSDKAPQKTIFVLKILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTI 240

Query: 241 QELLSLISTEDHPIT 255
           QELLSLISTEDHPIT
Sbjct: 241 QELLSLISTEDHPIT 255


>gi|226246519 zinc finger, MYND-type containing 12 isoform 1 [Homo
           sapiens]
          Length = 365

 Score =  449 bits (1155), Expect = e-126
 Identities = 227/234 (97%), Positives = 229/234 (97%)

Query: 22  AWPAAAAAAAGLGRIVQAEEYLFQAQWTVLKSTDCSNATHSLLHRNLGLLYIAKKNYEEA 81
           A+   A A+ GLGRIVQAEEYLFQAQWTVLKSTDCSNATHSLLHRNLGLLYIAKKNYEEA
Sbjct: 132 AYLLLAEASLGLGRIVQAEEYLFQAQWTVLKSTDCSNATHSLLHRNLGLLYIAKKNYEEA 191

Query: 82  RYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKLDLADTLYTKVSEIWHAYLNNH 141
           RYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKLDLADTLYTKVSEIWHAYLNNH
Sbjct: 192 RYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKLDLADTLYTKVSEIWHAYLNNH 251

Query: 142 YQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFVLK 201
           YQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFVLK
Sbjct: 252 YQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFVLK 311

Query: 202 ILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTIQELLSLISTEDHPIT 255
           ILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTIQELLSLISTEDHPIT
Sbjct: 312 ILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTIQELLSLISTEDHPIT 365


>gi|156938257 leucine rich repeat containing 16B [Homo sapiens]
          Length = 1372

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 27/114 (23%), Positives = 44/114 (38%), Gaps = 12/114 (10%)

Query: 105 GGYFHLANIFYDLKKLDLADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDL--------- 155
           GG+        D   L   + +   V  I+HA  N  + +L  +H++  DL         
Sbjct: 154 GGFSETYAALCDYNGLHCREEVQWDVDTIYHAEDNREFNLLDFSHLESRDLALMVAALAY 213

Query: 156 ---LGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFVLKILVMF 206
                KL+  D  L      + +  L+   ++ E   D A  KT FV K+  +F
Sbjct: 214 NQWFTKLYCKDLRLGSEVLEQVLHTLSKSGSLEELVLDNAGLKTDFVQKLAGVF 267


>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
          Length = 705

 Score = 32.0 bits (71), Expect = 0.54
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 23/129 (17%)

Query: 63  LLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTE-DIRTSGGYFHLANIFYDLKKLD 121
           +L+ N    Y+  ++YE+A            C +  + D + +  YFH+      LK   
Sbjct: 141 VLYTNRAQAYMKLEDYEKA---------LVDCEWALKCDEKCTKAYFHMGKANLALKNYS 191

Query: 122 LADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSI 181
           ++   Y K+ EI     N   Q   + ++ Q+DL  K         + QE EA  +L S 
Sbjct: 192 VSRECYKKILEI-----NPKLQTQVKGYLNQVDLQEKA--------DLQEKEAHELLDSG 238

Query: 182 LNIRESTSD 190
            N   +T +
Sbjct: 239 KNTAVTTKN 247


>gi|38570062 hypothetical protein LOC51608 [Homo sapiens]
          Length = 327

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 17/54 (31%), Positives = 26/54 (48%)

Query: 61  HSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIF 114
           H  LH+ L L    ++NY E+RYH  +      CA    +  TS G+    ++F
Sbjct: 142 HPRLHQLLALTLWKEQNYCESRYHFLHSADGEGCANMLVEYSTSRGFRSEVDMF 195


>gi|45243501 BCL2-like 13 (apoptosis facilitator) [Homo sapiens]
          Length = 485

 Score = 30.0 bits (66), Expect = 2.0
 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 3/64 (4%)

Query: 187 STSDKAPQKTIFVLKILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTIQELLSL 246
           ++S   P    +  K +V+ Y  +++  K QE   + LS  +  QLD+  QS  QE+L  
Sbjct: 2   ASSSTVPLGFHYETKYVVLSYLGLLSQEKLQE---QHLSSPQGVQLDIASQSLDQEILLK 58

Query: 247 ISTE 250
           + TE
Sbjct: 59  VKTE 62


>gi|18104962 amyloid beta precursor protein-binding protein 2 [Homo
           sapiens]
          Length = 585

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 21/85 (24%), Positives = 42/85 (49%), Gaps = 7/85 (8%)

Query: 76  KNYEEARYHLANDIYFASC-----AFGTEDIRTSGGYFHLANIFYDLKKLDLADTLYTKV 130
           K  E+     A+D++ +S      AFG  +++T+  Y +L  ++  ++K   A+ ++ K 
Sbjct: 396 KETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKA 455

Query: 131 SEIWHAYLNNH-YQV-LSQAHIQQM 153
            +I    L    Y+V LS  H+  +
Sbjct: 456 IQIKEQLLGQEDYEVALSVGHLASL 480


>gi|156523253 RWD domain containing 2A [Homo sapiens]
          Length = 292

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 147 QAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFV--LKILV 204
           Q  + +M++L  +F N   +    + E +  LT+I    E T +  P K  FV  L+I  
Sbjct: 10  QLQLLEMEMLFSMFPNQGEV----KLEDVNALTNIKRYLEGTREALPPKIEFVITLQIEE 65

Query: 205 MFYYLMMNSSKAQEYGMRALSL-AKEQQLDVHEQSTIQE-LLSLISTED 251
               + +  +    Y   AL L  +  +LD H+Q  + + L S I T D
Sbjct: 66  PKVKIDLQVTMPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFD 114


>gi|34304360 nephrocystin 3 [Homo sapiens]
          Length = 1330

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 37/176 (21%), Positives = 66/176 (37%), Gaps = 14/176 (7%)

Query: 55   DCSNATHSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIF 114
            DC+ + +     NL  L   KK Y++A       +     A   +    +    HLA ++
Sbjct: 1133 DCAQSLN-----NLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILY 1187

Query: 115  YDLKKLDLADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEA 174
              + KLD A  LY    EI        +  ++ A +    L  ++          +  EA
Sbjct: 1188 KKMGKLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQM---------KKHVEA 1238

Query: 175  IRILTSILNIRESTSDKAPQKTIFVLKILVMFYYLMMNSSKAQEYGMRALSLAKEQ 230
            + +    L I E +  +   +    LK L +  Y   +  KA E   RA+ + + +
Sbjct: 1239 LPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEGGDFEKAAELYKRAMEIKEAE 1294


>gi|155722985 SMC5 protein [Homo sapiens]
          Length = 1101

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 18/65 (27%), Positives = 35/65 (53%), Gaps = 5/65 (7%)

Query: 149 HIQQMDLLGKLFENDTGLD----EAQEAEAIRILTSILNIRESTSDKAPQKTIFVLKILV 204
           HI   DL   +FE+   ++    E ++ + +R+  +++  + S +DKAP +++  LK   
Sbjct: 503 HIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRV-NAVIAPKSSYADKAPSRSLNELKQYG 561

Query: 205 MFYYL 209
            F YL
Sbjct: 562 FFSYL 566


>gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]
          Length = 526

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 8/63 (12%)

Query: 61  HSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKL 120
           HS +  N+G +Y   KN  EA       I          D   +  YF    ++Y  +K 
Sbjct: 36  HSRICFNIGCMYTILKNMTEAEKAFTRSI--------NRDKHLAVAYFQRGMLYYQTEKY 87

Query: 121 DLA 123
           DLA
Sbjct: 88  DLA 90


>gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens]
          Length = 526

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 8/63 (12%)

Query: 61  HSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKL 120
           HS +  N+G +Y   KN  EA       I          D   +  YF    ++Y  +K 
Sbjct: 36  HSRICFNIGCMYTILKNMTEAEKAFTRSI--------NRDKHLAVAYFQRGMLYYQTEKY 87

Query: 121 DLA 123
           DLA
Sbjct: 88  DLA 90


>gi|21389483 leucine-rich repeats and guanylate kinase domain
           containing [Homo sapiens]
          Length = 825

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 2/81 (2%)

Query: 140 NHYQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRIL--TSILNIRESTSDKAPQKTI 197
           +H Q+ S   ++  DLL  +   D  + E +E E I+ L    +LN+ E+   +  +   
Sbjct: 288 SHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLENPIQEKSEYWF 347

Query: 198 FVLKILVMFYYLMMNSSKAQE 218
           FV+ +L+    L     K +E
Sbjct: 348 FVIFMLLRLTELDQKKIKVEE 368


>gi|45237195 Janus kinase and microtubule interacting protein 2
           [Homo sapiens]
          Length = 810

 Score = 28.1 bits (61), Expect = 7.8
 Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 121 DLADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDLLGKLF--ENDTGLDEAQEAEAIRIL 178
           DL ++L  + SE+    L   YQ L +A+    +  G +   E +    E  +AE +R  
Sbjct: 464 DLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYK 523

Query: 179 TSILNIRESTSDK 191
             I ++  + + K
Sbjct: 524 AKIEDLEATLAQK 536


>gi|38201680 meiotic recombination protein SPO11 isoform b [Homo
           sapiens]
          Length = 358

 Score = 28.1 bits (61), Expect = 7.8
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 8/61 (13%)

Query: 156 LGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFVLKILVMFYYLMMNSSK 215
           L   FE+  GL         +I        +S S K+ QK   +LKIL M Y L+ +++ 
Sbjct: 41  LASRFEDSVGLQMVSHCTTRKI--------KSDSPKSAQKFSLILKILSMIYKLVQSNTY 92

Query: 216 A 216
           A
Sbjct: 93  A 93


>gi|46358428 selective LIM binding factor homolog [Homo sapiens]
          Length = 1749

 Score = 28.1 bits (61), Expect = 7.8
 Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 6/82 (7%)

Query: 99   EDIRTSGGYFHLANIFYDLKKLDLADTLYTK---VSEIWHAYLNNHYQVLSQAHI---QQ 152
            +++   G Y     ++  +++ DLA T+Y K     ++      +H  +LS  H+   ++
Sbjct: 979  QEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKE 1038

Query: 153  MDLLGKLFENDTGLDEAQEAEA 174
            ++  G+L E +    EAQE +A
Sbjct: 1039 LEAEGRLQEAEYHYLEAQEWKA 1060


>gi|133922609 hypothetical protein LOC23383 [Homo sapiens]
          Length = 613

 Score = 28.1 bits (61), Expect = 7.8
 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 11/99 (11%)

Query: 65  HRNLG-LLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKLDLA 123
           H  LG +LY   KN E+AR HL      +      ED++       L+ ++     +D A
Sbjct: 68  HLQLGSVLYHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASL-LSELYCQENSVDAA 126

Query: 124 DTLYTKVSEI------WHAYLNNHYQVLSQAHIQQMDLL 156
             L  K  +I      WH  L      L+Q H  + DL+
Sbjct: 127 KPLLRKAIQISQQTPYWHCRL---LFQLAQLHTLEKDLV 162


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.131    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,914,991
Number of Sequences: 37866
Number of extensions: 291966
Number of successful extensions: 837
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 834
Number of HSP's gapped (non-prelim): 17
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.