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Search of human proteins with 225543114
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
(612 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225543118 solute carrier organic anion transporter family, me... 1260 0.0
gi|225543114 solute carrier organic anion transporter family, me... 1260 0.0
gi|8394291 solute carrier organic anion transporter family, memb... 1061 0.0
gi|225543116 solute carrier organic anion transporter family, me... 938 0.0
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 501 e-141
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 501 e-141
gi|9790233 solute carrier organic anion transporter family, memb... 494 e-139
gi|225543525 solute carrier organic anion transporter family, me... 491 e-138
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 466 e-131
gi|222831575 solute carrier organic anion transporter family, me... 324 1e-88
gi|222831573 solute carrier organic anion transporter family, me... 324 1e-88
gi|188528663 solute carrier organic anion transporter family, me... 306 5e-83
gi|38679890 solute carrier organic anion transporter family, mem... 276 3e-74
gi|223634012 solute carrier organic anion transporter family, me... 272 6e-73
gi|6005820 solute carrier organic anion transporter family, memb... 272 6e-73
gi|223634014 solute carrier organic anion transporter family, me... 258 1e-68
gi|39777594 solute carrier organic anion transporter family memb... 251 1e-66
gi|225637473 solute carrier organic anion transporter family, me... 249 7e-66
gi|225637475 solute carrier organic anion transporter family, me... 214 2e-55
gi|93277099 solute carrier organic anion transporter family, mem... 198 1e-50
gi|225637477 solute carrier organic anion transporter family, me... 197 2e-50
gi|11863156 RECK protein precursor [Homo sapiens] 37 0.069
gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Ho... 32 1.3
gi|9945322 solute carrier family 17, member 7 [Homo sapiens] 32 1.7
gi|12383051 transmembrane protein with EGF-like and two follista... 31 3.8
gi|54873613 agrin [Homo sapiens] 30 5.0
gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo ... 30 5.0
gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [... 30 6.5
gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor [... 30 6.5
gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor [... 30 6.5
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 1260 bits (3260), Expect = 0.0
Identities = 612/612 (100%), Positives = 612/612 (100%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC
Sbjct: 119 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 178
Query: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF
Sbjct: 179 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 238
Query: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS
Sbjct: 239 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 298
Query: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY
Sbjct: 299 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 358
Query: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR
Sbjct: 359 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 418
Query: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS
Sbjct: 419 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 478
Query: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV
Sbjct: 479 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 538
Query: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV
Sbjct: 539 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 598
Query: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPASHCYSIPDLHN 540
LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPASHCYSIPDLHN
Sbjct: 599 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPASHCYSIPDLHN 658
Query: 541 ATDTNKFSCHFTACKTYISGTNCDTGHSVNSPKHCSTFHFKEKLCFKTQKFYNQERKNNG 600
ATDTNKFSCHFTACKTYISGTNCDTGHSVNSPKHCSTFHFKEKLCFKTQKFYNQERKNNG
Sbjct: 659 ATDTNKFSCHFTACKTYISGTNCDTGHSVNSPKHCSTFHFKEKLCFKTQKFYNQERKNNG 718
Query: 601 VYKIPKGKLHYK 612
VYKIPKGKLHYK
Sbjct: 719 VYKIPKGKLHYK 730
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 1260 bits (3260), Expect = 0.0
Identities = 612/612 (100%), Positives = 612/612 (100%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC
Sbjct: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
Query: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF
Sbjct: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
Query: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS
Sbjct: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
Query: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY
Sbjct: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
Query: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR
Sbjct: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
Query: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS
Sbjct: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
Query: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV
Sbjct: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
Query: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV
Sbjct: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
Query: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPASHCYSIPDLHN 540
LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPASHCYSIPDLHN
Sbjct: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPASHCYSIPDLHN 540
Query: 541 ATDTNKFSCHFTACKTYISGTNCDTGHSVNSPKHCSTFHFKEKLCFKTQKFYNQERKNNG 600
ATDTNKFSCHFTACKTYISGTNCDTGHSVNSPKHCSTFHFKEKLCFKTQKFYNQERKNNG
Sbjct: 541 ATDTNKFSCHFTACKTYISGTNCDTGHSVNSPKHCSTFHFKEKLCFKTQKFYNQERKNNG 600
Query: 601 VYKIPKGKLHYK 612
VYKIPKGKLHYK
Sbjct: 601 VYKIPKGKLHYK 612
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 1061 bits (2743), Expect = 0.0
Identities = 521/522 (99%), Positives = 522/522 (100%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC
Sbjct: 119 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 178
Query: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF
Sbjct: 179 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 238
Query: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS
Sbjct: 239 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 298
Query: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY
Sbjct: 299 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 358
Query: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR
Sbjct: 359 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 418
Query: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS
Sbjct: 419 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 478
Query: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV
Sbjct: 479 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 538
Query: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV
Sbjct: 539 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 598
Query: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 522
LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR+
Sbjct: 599 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRH 640
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 938 bits (2425), Expect = 0.0
Identities = 472/522 (90%), Positives = 473/522 (90%), Gaps = 49/522 (9%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN
Sbjct: 119 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN-- 176
Query: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
GCVQTVAIIGPIF
Sbjct: 177 -----------------------------------------------GCVQTVAIIGPIF 189
Query: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS
Sbjct: 190 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 249
Query: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY
Sbjct: 250 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 309
Query: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR
Sbjct: 310 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 369
Query: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS
Sbjct: 370 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 429
Query: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV
Sbjct: 430 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 489
Query: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV
Sbjct: 490 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 549
Query: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 522
LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR+
Sbjct: 550 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRH 591
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 501 bits (1289), Expect = e-141
Identities = 237/530 (44%), Positives = 345/530 (65%), Gaps = 18/530 (3%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
MG+G L ++P F M QY+YE S + S S +E+ +Q+ + S EC
Sbjct: 96 MGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQILRPTQDPS------EC 149
Query: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
+ S MW+YV +GN++RG+GETPI PLGI+Y++DFA +N+ YIG V+T AIIGP+
Sbjct: 150 TKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLI 209
Query: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
G LL S CA +YVD GFVN D + ITP D +WVGAWW G+LI +++L A+PF++LP +
Sbjct: 210 GLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNT 269
Query: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
LP+ +++ I +++ D Q + + K + +DFLP +K+L NP+Y L+
Sbjct: 270 LPKEGLETNAD-------IIKNENEDKQKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLF 321
Query: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
+ S +QFN+ M+++ PKY+EQQYG SSS A F++G+ N+P + +G GG++MKKF+
Sbjct: 322 ILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFK 381
Query: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
I+V AA + S+ YLL+ F + CENS V G+ SY+G Y E +F+DCN
Sbjct: 382 ITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNV 441
Query: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
C C W+P+CG NG++Y+SACLAGC+TS +G N++F NC+C+ SGNSS ++
Sbjct: 442 DCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCI----QTSGNSSAVL 497
Query: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
G C K C M YFL++S ++S+ SL IPGY++LLRC+K + KS +G++T RV
Sbjct: 498 GLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRV 557
Query: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPAS 530
AGIPAP+YFG L+D++CL WG +CG G+CR+YDS FRY +PA+
Sbjct: 558 FAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAA 607
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 501 bits (1289), Expect = e-141
Identities = 237/530 (44%), Positives = 345/530 (65%), Gaps = 18/530 (3%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
MG+G L ++P F M QY+YE S + S S +E+ +Q+ + S EC
Sbjct: 96 MGLGCFLKSLPHFLMNQYEYESTVSVSGNLSSNSFLCMENGTQILRPTQDPS------EC 149
Query: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
+ S MW+YV +GN++RG+GETPI PLGI+Y++DFA +N+ YIG V+T AIIGP+
Sbjct: 150 TKEVKSLMWVYVLVGNIVRGMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLI 209
Query: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
G LL S CA +YVD GFVN D + ITP D +WVGAWW G+LI +++L A+PF++LP +
Sbjct: 210 GLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNT 269
Query: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
LP+ +++ I +++ D Q + + K + +DFLP +K+L NP+Y L+
Sbjct: 270 LPKEGLETNAD-------IIKNENEDKQKEEVKKEKY-GITKDFLPFMKSLSCNPIYMLF 321
Query: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
+ S +QFN+ M+++ PKY+EQQYG SSS A F++G+ N+P + +G GG++MKKF+
Sbjct: 322 ILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFK 381
Query: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
I+V AA + S+ YLL+ F + CENS V G+ SY+G Y E +F+DCN
Sbjct: 382 ITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNV 441
Query: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
C C W+P+CG NG++Y+SACLAGC+TS +G N++F NC+C+ SGNSS ++
Sbjct: 442 DCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTGINMVFQNCSCI----QTSGNSSAVL 497
Query: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
G C K C M YFL++S ++S+ SL IPGY++LLRC+K + KS +G++T RV
Sbjct: 498 GLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRV 557
Query: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSIPAS 530
AGIPAP+YFG L+D++CL WG +CG G+CR+YDS FRY +PA+
Sbjct: 558 FAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAA 607
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 494 bits (1271), Expect = e-139
Identities = 235/524 (44%), Positives = 347/524 (66%), Gaps = 10/524 (1%)
Query: 1 MGVGTLLIAMPQFFMEQYKYER---YSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKIS 57
MG G++L ++P FFM Y+Y + +PS NST S+S CL+ + +S S +
Sbjct: 104 MGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLSTCLINQT----LSFNGTSPEIVE 159
Query: 58 NECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIG 117
+C ++ S MWIYVF+GN+LRGIGETPI PLGI+Y+DDFA E +++ Y+G + + +IG
Sbjct: 160 KDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIG 219
Query: 118 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 177
P+ GF LGSL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++G+ S+++++PF++L
Sbjct: 220 PVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFL 279
Query: 178 PKSLPRSQSREDSNSSSEKSKFIID-DHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPV 236
PK+ + Q + S K D + T T QG+N + + F SLK++ NP+
Sbjct: 280 PKNPNKPQKERKISLSLHVLKTNDDRNQTANLTNQGKN--VTKNVTGFFQSLKSILTNPL 337
Query: 237 YFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVM 296
Y ++L + +Q +S G TY KY+EQQYGQS+S ANF++G+I IP VA G+F GG ++
Sbjct: 338 YVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFII 397
Query: 297 KKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFS 356
KKF++S+ G AK +S+ +L L F L CE+ VAGLT++Y G V+ H S
Sbjct: 398 KKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLS 457
Query: 357 DCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNS 416
CNS C C E++WEP+CG NGITY+S CLAGC++S+ K+ +FYNC+CV + ++ N
Sbjct: 458 YCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNY 517
Query: 417 SGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTL 476
S +G C +DN C + F ++ I VI S + GG +L ++ ++P+LK+ A+G ++
Sbjct: 518 SAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSM 577
Query: 477 AIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVF 520
IR L GI AP+YFG LID +C+KW CG++G+CR+Y+S F
Sbjct: 578 VIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFF 621
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 491 bits (1263), Expect = e-138
Identities = 246/595 (41%), Positives = 366/595 (61%), Gaps = 39/595 (6%)
Query: 1 MGVGTLLIAMPQFFMEQYKYER---YSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKIS 57
MG+G +L A+P FFM Y+Y + + S NST ++S CL+ +S+ S +
Sbjct: 104 MGIGGVLTALPHFFMGYYRYSKETNINSSENSTSTLSTCLINQI----LSLNRASPEIVG 159
Query: 58 NECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIG 117
C ++ S MWIYVF+GN+LRGIGETPI PLG++Y+DDFA E +++ Y+G + +A+IG
Sbjct: 160 KGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIG 219
Query: 118 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 177
PI GF LGSL +K+YVDIG+V+L I ITP D +WVGAWWL +L++G+ S+++++PF++L
Sbjct: 220 PIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFL 279
Query: 178 PKSLPRSQSREDSNSSSEKSKFIID-DHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPV 236
P++ + Q ++ S + + D T T QG+N I + F S K++ NP+
Sbjct: 280 PQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKN--ITKNVTGFFQSFKSILTNPL 337
Query: 237 YFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVM 296
Y +++ + +Q +S G TY KY+EQQYGQ SS+AN ++G+I IP A G+F GG ++
Sbjct: 338 YVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYII 397
Query: 297 KKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFS 356
KKF+++ G AK ++V +L F + CEN VAGLT++Y G PV+ H S
Sbjct: 398 KKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLS 457
Query: 357 DCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNS 416
CNS C C E++WEP+CG NGITY+S CLAGC++S+ + K I+FYNC+C+ + ++ N
Sbjct: 458 YCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNY 517
Query: 417 SGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTL 476
S +G C +D+ C + F +F+ I V+ + +LGG +L+++ ++P+LKS ALG +++
Sbjct: 518 SAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSM 577
Query: 477 AIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVF---------------- 520
IR L GI AP+YFG LIDT+C+KW CG+RGSCR Y+S F
Sbjct: 578 VIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSL 637
Query: 521 ------------RYQIKSIPASHCYSIPDLHNATDTNKFSCHFTACKTYISGTNC 563
+YQ K I AS S+ D N NK + HF S T+C
Sbjct: 638 VLYIILIYAMKKKYQEKDINASENGSVMDEANLESLNK-NKHFVPSAGADSETHC 691
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 466 bits (1198), Expect = e-131
Identities = 221/523 (42%), Positives = 341/523 (65%), Gaps = 14/523 (2%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYS---PSSNSTLSISPCLLE---SSSQLPVSVMEKSKS 54
MG G++L+A+P FFM Y+Y + + PS NST ++ CL+ S ++ P ++E+
Sbjct: 57 MGTGSILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERG-- 114
Query: 55 KISNECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVA 114
C ++ S MWIYVF+GN+LRGIGETPI PLGI+Y+DDFA E +++ Y+G V +
Sbjct: 115 -----CVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMG 169
Query: 115 IIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPF 174
+ G +F F+LGSL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++GI+S+++++PF
Sbjct: 170 MTGLVFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPF 229
Query: 175 WYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGN 234
++LP + P +E S D I + F SLK++ N
Sbjct: 230 FFLPLN-PNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTN 288
Query: 235 PVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGI 294
P+Y +++ + + +S +TY K +EQQYG S+S+ NF++G++ +PAVA+G+FSGG
Sbjct: 289 PLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGY 348
Query: 295 VMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERAL 354
++KKF++S+ G AKL S+ L + F L CE+ VAGLT++Y G PV H
Sbjct: 349 IIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVP 408
Query: 355 FSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSG 414
S CNS C C E++WEP+CG NGITY+S CLAGC++S+ + + I+FYNC+CV + ++
Sbjct: 409 LSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNK 468
Query: 415 NSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIY 474
N S +G C +D+ C + + VI V+ ++ ++G +L++R ++P+LK+ A+G +
Sbjct: 469 NYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFH 528
Query: 475 TLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDS 517
++ +R L GI P+YFG LIDT+C+KW CG+RG+CR+Y+S
Sbjct: 529 SMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNS 571
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 324 bits (831), Expect = 1e-88
Identities = 181/545 (33%), Positives = 295/545 (54%), Gaps = 49/545 (8%)
Query: 1 MGVGTLLIAMPQFFMEQYKYE----RYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKI 56
M +G LL A+P+F QYKYE R+ + + + +
Sbjct: 116 MALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLI--------- 166
Query: 57 SNECEVDTSSSMWIYVFLG-NLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAI 115
C T+++M + +G +L GIG TP+QPLG++Y+DD +++ YIG + T+ +
Sbjct: 167 ---CRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLV 223
Query: 116 IGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFW 175
GP GF+LGS C K+YVD F++ ++ ITP DP+W+GAWW G+L+ G + +++ +
Sbjct: 224 FGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMF 283
Query: 176 YLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGEN------------AKIMEMARD 223
P+SLP S + E + ++ + +Y+ P+ N A + R
Sbjct: 284 GFPQSLP-----PHSEPAMESEQAMLSER-EYERPKPSNGVLRHPLEPDSSASCFQQLRV 337
Query: 224 FLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIP 283
K+L NPV+ + + ++ + G + KY+EQQ+ ++S AN ++G+ IP
Sbjct: 338 IPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIP 397
Query: 284 AVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY-Q 342
LGIF GG+++KK +S GA ++ + ++ ++S LGC+ VAG+TV Y
Sbjct: 398 CACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGN 457
Query: 343 GTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYN 402
T P S + +S CN+ C+C + P+CG +GITY+SAC AGC ++N +G
Sbjct: 458 STAPGSALDP--YSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG------- 508
Query: 403 CTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCI 462
C C+ ++ N++ + G+C GC + FL FL + I S ++ P I+L+R +
Sbjct: 509 CACLTTVPAE--NATVVPGKCPSP-GCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTV 565
Query: 463 KPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 522
P+LKS+ALG+ L +R+L IP P+ FG ID++CL W CG +G+C LYD+ V+RY
Sbjct: 566 SPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYDNVVYRY 624
Query: 523 QIKSI 527
SI
Sbjct: 625 LYVSI 629
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 324 bits (831), Expect = 1e-88
Identities = 181/545 (33%), Positives = 295/545 (54%), Gaps = 49/545 (8%)
Query: 1 MGVGTLLIAMPQFFMEQYKYE----RYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKI 56
M +G LL A+P+F QYKYE R+ + + + +
Sbjct: 116 MALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLI--------- 166
Query: 57 SNECEVDTSSSMWIYVFLG-NLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAI 115
C T+++M + +G +L GIG TP+QPLG++Y+DD +++ YIG + T+ +
Sbjct: 167 ---CRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLV 223
Query: 116 IGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFW 175
GP GF+LGS C K+YVD F++ ++ ITP DP+W+GAWW G+L+ G + +++ +
Sbjct: 224 FGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMF 283
Query: 176 YLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGEN------------AKIMEMARD 223
P+SLP S + E + ++ + +Y+ P+ N A + R
Sbjct: 284 GFPQSLP-----PHSEPAMESEQAMLSER-EYERPKPSNGVLRHPLEPDSSASCFQQLRV 337
Query: 224 FLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIP 283
K+L NPV+ + + ++ + G + KY+EQQ+ ++S AN ++G+ IP
Sbjct: 338 IPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIP 397
Query: 284 AVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY-Q 342
LGIF GG+++KK +S GA ++ + ++ ++S LGC+ VAG+TV Y
Sbjct: 398 CACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGN 457
Query: 343 GTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYN 402
T P S + +S CN+ C+C + P+CG +GITY+SAC AGC ++N +G
Sbjct: 458 STAPGSALDP--YSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG------- 508
Query: 403 CTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCI 462
C C+ ++ N++ + G+C GC + FL FL + I S ++ P I+L+R +
Sbjct: 509 CACLTTVPAE--NATVVPGKCPSP-GCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTV 565
Query: 463 KPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 522
P+LKS+ALG+ L +R+L IP P+ FG ID++CL W CG +G+C LYD+ V+RY
Sbjct: 566 SPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYDNVVYRY 624
Query: 523 QIKSI 527
SI
Sbjct: 625 LYVSI 629
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 306 bits (783), Expect = 5e-83
Identities = 169/528 (32%), Positives = 274/528 (51%), Gaps = 39/528 (7%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
+ G ++ +P F E Y+Y S +NS L C + LP S + E
Sbjct: 108 LAAGAFILTLPHFLSEPYQYTLASTGNNSRLQAELCQ-KHWQDLPPSKCHSTTQNPQKE- 165
Query: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
+SSMW + + LL GIG PIQP GI+Y+DDF+ N+ YI + +++ GP F
Sbjct: 166 ----TSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNSPLYISILFAISVFGPAF 221
Query: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
G+LLGS+ +++VD G VN + + P DP+W+GAWWLG LI+ + +L + PF++ P++
Sbjct: 222 GYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLISSALLVLTSFPFFFFPRA 281
Query: 181 LP----RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPV 236
+P R+ + D E++K +++ + F L N +
Sbjct: 282 MPIGAKRAPATADEARKLEEAK--------------SRGSLVDFIKRFPCIFLRLLMNSL 327
Query: 237 YFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVM 296
+ L + + + G+ T+ K++E+QYG S++ ANF+IG +N+PA ALG+ GGI+M
Sbjct: 328 FVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPAAALGMLFGGILM 387
Query: 297 KKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFS 356
K+F S+ ++ +L + LF +GC VA + Y + S H ++
Sbjct: 388 KRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEV---YPPSTSSSIHPQS--P 442
Query: 357 DCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRS---GKNIIFYNCTCVGIAASKS 413
C C C ++ + P+CG+NGI Y+S C AGC N S K +I+ NC+CV
Sbjct: 443 ACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYLNCSCV-----TG 497
Query: 414 GNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGI 473
G++S G C C L + + S + P Y+++LR + + KSFA+G+
Sbjct: 498 GSASAKTGSCPVP--CAHFLLPAIFLISFVSLIACISHNPLYMMVLRVVNQEEKSFAIGV 555
Query: 474 YTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR 521
L +R+LA +P+P +G+ ID SC++W G RG+C YD++ R
Sbjct: 556 QFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDALR 603
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 276 bits (707), Expect = 3e-74
Identities = 161/534 (30%), Positives = 269/534 (50%), Gaps = 51/534 (9%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
+G+G L+ ++PQFF +YK +L C+ ++ S C
Sbjct: 182 IGLGALVFSLPQFFSGEYKL--------GSLFEDTCVT---------------TRNSTSC 218
Query: 61 EVDTSS-SMWIYVF-LGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGP 118
TSS S ++YVF LG LL G G TP+ LG A+LDD ++ YIG ++I+GP
Sbjct: 219 TSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGP 278
Query: 119 IFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLP 178
G++LG +Y+D+ + +T DP+W+GAWW+G+L++ I + +PF P
Sbjct: 279 AIGYVLGGQLLTIYIDVAMG--ESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFP 336
Query: 179 KSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYF 238
K LP + + +S +Q+ + K + +DF +LKNL N V+
Sbjct: 337 KHLPGTAEIQAGKTSQA-----------HQSNSNADVKFGKSIKDFPAALKNLMKNAVFM 385
Query: 239 LYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKK 298
+ +++ + G T+ PK+IE Q+G +SS A + G + IP ALG GG ++ K
Sbjct: 386 CLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSK 445
Query: 299 FRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDC 358
FR++ K L +S L CEN AG++ SY GT + L + C
Sbjct: 446 FRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELG----NLIAPC 501
Query: 359 NSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVG-----IAASKS 413
N+ C CS + + P+CG+ G+ Y S C AGC K ++YNC+C+ + +++
Sbjct: 502 NANCNCSRSYYYPVCGD-GVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAET 560
Query: 414 GNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGI 473
G+C + C ++ ++ + ++ +T + G P + +LRC+ + +S ALGI
Sbjct: 561 FGFEAKAGKC--ETHCAKLPIFLCIFFIVIIFTF-MAGTPITVSILRCVNHRQRSLALGI 617
Query: 474 YTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKSI 527
+ +R+L IP P+ FG ID++C+ W CG +G+C +YD+ + + +I
Sbjct: 618 QFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAI 671
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 272 bits (696), Expect = 6e-73
Identities = 168/538 (31%), Positives = 272/538 (50%), Gaps = 41/538 (7%)
Query: 6 LLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSSQLPVSVMEKSKSKISNECEVDT 64
LL+ +P F E Y+Y+ SP S CL +S+ P S S S+ E
Sbjct: 108 LLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA--PASA--PSNGNCSSYTETQH 163
Query: 65 SSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLL 124
S + I +F+ L G+G PIQP GI+Y+DDFA N+ Y+G + V ++GP F L
Sbjct: 164 LSVVGI-MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGL 222
Query: 125 GSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPR- 183
GSL +LYVDI + I++T KDP+WVGAWWLG+LIA LAA+P+++ PK +P+
Sbjct: 223 GSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKE 282
Query: 184 ---------------SQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSL 228
S +R+ +S S++S D N +++ + F L
Sbjct: 283 KRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVL 342
Query: 229 KNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALG 288
+P++ L + + + GM T+ PK++E+Q+ ++S AN +IG ++ P+V +G
Sbjct: 343 LQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVG 402
Query: 289 IFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVS 348
I GG+++K+ + G L L + L LF +GC + +AG+T + +
Sbjct: 403 IVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-----HQTSA 457
Query: 349 YHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT----SNRSGKNIIFYNC 403
+ L C C C + P+C + Y++ C AGC + + + NC
Sbjct: 458 HPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNC 517
Query: 404 TCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIK 463
+CV GN + G C D+ C + + FL++ + S L P ++L+LR +K
Sbjct: 518 SCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVK 569
Query: 464 PQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR 521
+ K+ A+GI + +R+LA +P+PV G IDT+C+ W CG R CR Y++++ R
Sbjct: 570 KEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLR 626
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 272 bits (696), Expect = 6e-73
Identities = 168/538 (31%), Positives = 272/538 (50%), Gaps = 41/538 (7%)
Query: 6 LLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSSQLPVSVMEKSKSKISNECEVDT 64
LL+ +P F E Y+Y+ SP S CL +S+ P S S S+ E
Sbjct: 130 LLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA--PASA--PSNGNCSSYTETQH 185
Query: 65 SSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLL 124
S + I +F+ L G+G PIQP GI+Y+DDFA N+ Y+G + V ++GP F L
Sbjct: 186 LSVVGI-MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGL 244
Query: 125 GSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPR- 183
GSL +LYVDI + I++T KDP+WVGAWWLG+LIA LAA+P+++ PK +P+
Sbjct: 245 GSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKE 304
Query: 184 ---------------SQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSL 228
S +R+ +S S++S D N +++ + F L
Sbjct: 305 KRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVL 364
Query: 229 KNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALG 288
+P++ L + + + GM T+ PK++E+Q+ ++S AN +IG ++ P+V +G
Sbjct: 365 LQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVG 424
Query: 289 IFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVS 348
I GG+++K+ + G L L + L LF +GC + +AG+T + +
Sbjct: 425 IVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-----HQTSA 479
Query: 349 YHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT----SNRSGKNIIFYNC 403
+ L C C C + P+C + Y++ C AGC + + + NC
Sbjct: 480 HPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNC 539
Query: 404 TCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIK 463
+CV GN + G C D+ C + + FL++ + S L P ++L+LR +K
Sbjct: 540 SCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVK 591
Query: 464 PQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR 521
+ K+ A+GI + +R+LA +P+PV G IDT+C+ W CG R CR Y++++ R
Sbjct: 592 KEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLR 648
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 258 bits (659), Expect = 1e-68
Identities = 148/471 (31%), Positives = 244/471 (51%), Gaps = 35/471 (7%)
Query: 72 VFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKL 131
+F+ L G+G PIQP GI+Y+DDFA N+ Y+G + V ++GP F LGSL +L
Sbjct: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
Query: 132 YVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPR-------- 183
YVDI + I++T KDP+WVGAWWLG+LIA LAA+P+++ PK +P+
Sbjct: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFR 167
Query: 184 --------SQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNP 235
S +R+ +S S++S D N +++ + F L +P
Sbjct: 168 RKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHP 227
Query: 236 VYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIV 295
++ L + + + GM T+ PK++E+Q+ ++S AN +IG ++ P+V +GI GG++
Sbjct: 228 IFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVL 287
Query: 296 MKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALF 355
+K+ + G L L + L LF +GC + +AG+T + ++ L
Sbjct: 288 VKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT-----HQTSAHPGLELS 342
Query: 356 SDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT----SNRSGKNIIFYNCTCVGIAA 410
C C C + P+C + Y++ C AGC + + + NC+CV
Sbjct: 343 PSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCV---- 398
Query: 411 SKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFA 470
GN + G C D+ C + + FL++ + S L P ++L+LR +K + K+ A
Sbjct: 399 -VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLA 454
Query: 471 LGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR 521
+GI + +R+LA +P+PV G IDT+C+ W CG R CR Y++++ R
Sbjct: 455 VGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-CGRRAVCRYYNNDLLR 504
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 251 bits (642), Expect = 1e-66
Identities = 157/520 (30%), Positives = 245/520 (47%), Gaps = 40/520 (7%)
Query: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
MG G+L+ A+P F +Y+ E + + +S+S L
Sbjct: 180 MGTGSLVFALPHFTAGRYEVELDAGVRTCPANPGAVCADSTSGL---------------- 223
Query: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
S + LG L G+G TP+ LG+ YLD+ + YI T AI+GP
Sbjct: 224 -----SRYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIAIFYTAAILGPAA 278
Query: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
G+L+G +Y ++G +T + P WVGAWW+G+L +G + AVP P+
Sbjct: 279 GYLIGGALLNIYTEMG----RRTELTTESPLWVGAWWVGFLGSGAAAFFTAVPILGYPRQ 334
Query: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
LP SQ ++ + D + N + RD S+ L NP + L
Sbjct: 335 LPGSQRYAVMRAAE------MHQLKDSSRGEASNPDFGKTIRDLPLSIWLLLKNPTFILL 388
Query: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
+ + GM T+ PK++E Q+ S+S A + G + +PA G F GG + K R
Sbjct: 389 CLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLR 448
Query: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
+ K L +V LL + +F+L C + +AG+T SY G+ H L + CN+
Sbjct: 449 LRGSAVIKFCLFCTVVS-LLGILVFSLHCPSVPMAGVTASYGGSLLPEGHLN-LTAPCNA 506
Query: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKN--IIFYNCTCVGIAASKSGNSSG 418
C C + P+CG +G+ Y S C AGC + + + ++ +C+C+ S SG
Sbjct: 507 ACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIPQNLS-SGFGHA 565
Query: 419 IVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAI 478
G+C C + L + I V+ +T L IP LRC++ +SFALGI + +
Sbjct: 566 TAGKCTST--CQRKPLLLVFIFVVIFFTF-LSSIPALTATLRCVRDPQRSFALGIQWIVV 622
Query: 479 RVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSN 518
R+L GIP P+ FG +ID +CL W +CG +GSC +Y ++
Sbjct: 623 RILGGIPGPIAFGWVIDKACLLWQ-DQCGQQGSCLVYQNS 661
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 249 bits (635), Expect = 7e-66
Identities = 160/565 (28%), Positives = 261/565 (46%), Gaps = 82/565 (14%)
Query: 4 GTLLIAMPQFFMEQYKYERYSPSS---------NSTLSISPCLLESSSQLPVSVMEKSKS 54
G L A+P F Y+ + + S+ NST ++ P
Sbjct: 208 GAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEP------------------- 248
Query: 55 KISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCV 110
C D+ ++ W+YV L +L G+G TPI LG YLDD ++N++ Y+ +
Sbjct: 249 ---PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
Query: 111 QTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLA 170
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 306 YVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
Query: 171 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD-------YQTPQGENAKIMEMA-- 221
P + PK LP ++ +K KF +D +D + + K+ M
Sbjct: 362 IFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFG 415
Query: 222 ---RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIG 278
RD + + N + + T + + +T+ PK+IE Q+G +S A+ G
Sbjct: 416 KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTG 475
Query: 279 LINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLT 338
+I +P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE+ ++ G+
Sbjct: 476 VIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGIN 535
Query: 339 VSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNI 398
+ Y ++ R L CN C C ++EP+CG +GITY + CLAGC S I
Sbjct: 536 IPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGI 595
Query: 399 IFY-NCTCVG--------------------IAASKSGNSSGIVGRCQKDNGCPQMFLYFL 437
Y CTCV + + N + G+C++ C + FL
Sbjct: 596 RNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C-NTLIPFL 652
Query: 438 VISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTS 497
V I ++ + I+ LR ++ + + FALG+ + +R LA IP P+YFG +IDT+
Sbjct: 653 VFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTT 712
Query: 498 CLKWGFKRCGSRGSCRLYDSNVFRY 522
C+ W + CG +GSC Y+ FR+
Sbjct: 713 CMLWQ-QECGVQGSCWEYNVTSFRF 736
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 214 bits (544), Expect = 2e-55
Identities = 152/553 (27%), Positives = 242/553 (43%), Gaps = 113/553 (20%)
Query: 4 GTLLIAMPQFFMEQYKYERYSPSS---------NSTLSISPCLLESSSQLPVSVMEKSKS 54
G L A+P F Y+ + + S+ NST ++ P
Sbjct: 208 GAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEP------------------- 248
Query: 55 KISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCV 110
C D+ ++ W+YV L +L G+G TPI LG YLDD ++N++ Y+ +
Sbjct: 249 ---PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
Query: 111 QTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLA 170
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 306 YVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
Query: 171 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKN 230
P + PK LP ++ +K KF +D +D + E + E A + S+
Sbjct: 362 IFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLK-EKSNNSEQADKKVSSMG- 413
Query: 231 LFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIF 290
FG V G+I +P+ +GI
Sbjct: 414 -FGKDVR----------------------------------------GVIIVPSAGVGIV 432
Query: 291 SGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYH 350
GG ++KK ++ +AKL + S L F +LF +GCE+ ++ G+ + Y ++
Sbjct: 433 LGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMP 492
Query: 351 ERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFY-NCTCVG-- 407
R L CN C C ++EP+CG +GITY + CLAGC S I Y CTCV
Sbjct: 493 HRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSR 552
Query: 408 ------------------IAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSL 449
+ + N + G+C++ C + FLV I ++ +
Sbjct: 553 QVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C-NTLIPFLVFLFIVTFITAC 609
Query: 450 GGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSR 509
I+ LR ++ + + FALG+ + +R LA IP P+YFG +IDT+C+ W + CG +
Sbjct: 610 AQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQ 668
Query: 510 GSCRLYDSNVFRY 522
GSC Y+ FR+
Sbjct: 669 GSCWEYNVTSFRF 681
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 198 bits (503), Expect = 1e-50
Identities = 124/507 (24%), Positives = 230/507 (45%), Gaps = 27/507 (5%)
Query: 29 STLSISPCLLESSSQLPVSVMEKSKS-KISNECE---VDTSSSMWIYVFLGNLLRGIGET 84
S L P + E + Q V + + + K+ + C+ + S + LG ++GI
Sbjct: 185 SLLCAFPSINEENKQSKVGIEDICEEIKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGM 244
Query: 85 PIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHIT 144
P+ LGI ++D+ + +A Y+G + ++IG G++LG+ K V + + T
Sbjct: 245 PLYILGITFIDENVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTT 302
Query: 145 ITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDH 204
+ P+W+ WW+ +L A +++ +P P ++P S + + K D
Sbjct: 303 VNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCFPNNMPGSTRIK---ARKRKQLHFFDSR 359
Query: 205 TDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQ 264
++ K+ +D +L L NPV + ++ + G + P Y+E
Sbjct: 360 L-------KDLKLGTNIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLEN 412
Query: 265 QYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSL 324
Q+ + + A + GL+ IP ALG GG+++ +S + + +SV +L + +
Sbjct: 413 QFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFI 472
Query: 325 FALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSAC 384
+ C AG+ Y GT + L + CN +C+CS + + +CG + I Y S C
Sbjct: 473 IFVRCNPVQFAGINEDYDGTGKLGN----LTAPCNEKCRCSSSIYSSICGRDDIEYFSPC 528
Query: 385 LAGCQTSNRSGKNIIFYNCTCVG---IAASKSGN-SSGIVGRCQKDNGCPQMFLYFLVIS 440
AGC S + ++YNC+C+ I A G+ G+C +F+ F+ +
Sbjct: 529 FAGCTYSKAQNQKKMYYNCSCIKEGLITADAEGDFIDARPGKCDAKCYKLPLFIAFIFST 588
Query: 441 VITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLK 500
+I S G+P + + R + +L+S ALG+ + +R+ IP P F + +TSC+
Sbjct: 589 LIFS---GFSGVPIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCIL 645
Query: 501 WGFKRCGSRGSCRLYDSNVFRYQIKSI 527
+CG G C +Y+ + + I
Sbjct: 646 RDVNKCGHTGRCWIYNKTKMAFLLVGI 672
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 197 bits (501), Expect = 2e-50
Identities = 123/429 (28%), Positives = 198/429 (46%), Gaps = 58/429 (13%)
Query: 4 GTLLIAMPQFFMEQYKYERYSPSS---------NSTLSISPCLLESSSQLPVSVMEKSKS 54
G L A+P F Y+ + + S+ NST ++ P
Sbjct: 208 GAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEP------------------- 248
Query: 55 KISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCV 110
C D+ ++ W+YV L +L G+G TPI LG YLDD ++N++ Y+ +
Sbjct: 249 ---PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
Query: 111 QTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLA 170
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 306 YVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
Query: 171 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD-------YQTPQGENAKIMEMA-- 221
P + PK LP ++ +K KF +D +D + + K+ M
Sbjct: 362 IFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFG 415
Query: 222 ---RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIG 278
RD + + N + + T + + +T+ PK+IE Q+G +S A+ G
Sbjct: 416 KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTG 475
Query: 279 LINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLT 338
+I +P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE+ ++ G+
Sbjct: 476 VIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGIN 535
Query: 339 VSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNI 398
+ Y ++ R L CN C C ++EP+CG +GITY + CLAGC S I
Sbjct: 536 IPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGI 595
Query: 399 IFY-NCTCV 406
Y CTCV
Sbjct: 596 RNYTECTCV 604
>gi|11863156 RECK protein precursor [Homo sapiens]
Length = 971
Score = 36.6 bits (83), Expect = 0.069
Identities = 14/27 (51%), Positives = 21/27 (77%), Gaps = 1/27 (3%)
Query: 362 CKCSETKWEPMCGENGITYVSACLAGC 388
C C++ ++ P+CG+NG TY SAC+A C
Sbjct: 633 CNCAD-QFVPVCGQNGRTYPSACIARC 658
Score = 33.5 bits (75), Expect = 0.59
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 13/77 (16%)
Query: 337 LTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGK 396
L YQ K +SY C C+ +E P+CG NG TY S C A S+R
Sbjct: 734 LCTLYQRGKSLSYK-----GPCQPFCRATE----PVCGHNGETYSSVCAA---YSDRVAV 781
Query: 397 NIIFYNCTCVGIAASKS 413
+ + +C VG+ + S
Sbjct: 782 D-YYGDCQAVGVLSEHS 797
>gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Homo
sapiens]
Length = 856
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 272 RANFVIGLINIP-AVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLF---AL 327
+ + ++G+I++ V LGIF+ KKF I + +L +FGYL+F+ +
Sbjct: 553 KMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFGYLIFMIFYKWLVF 612
Query: 328 GCENSDVA 335
E S VA
Sbjct: 613 SAETSRVA 620
>gi|9945322 solute carrier family 17, member 7 [Homo sapiens]
Length = 560
Score = 32.0 bits (71), Expect = 1.7
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 174 FWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFG 233
FWYL L +S S SE+ + I+D GE+AK+M F + F
Sbjct: 247 FWYLFWLLVSYESPALHPSISEEERKYIEDAI------GESAKLMNPLTKFSTPWRRFFT 300
Query: 234 NPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGL 279
+ + + + + + + ++ +P Y E+ +G S+ V L
Sbjct: 301 SMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSAL 346
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 30.8 bits (68), Expect = 3.8
Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 358 CNSRCKCSETKWEPMCGENGITYVSACL---AGCQTSNR 393
C CS+T + P+C +G +Y +AC A CQ +
Sbjct: 180 CVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEK 218
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 30.4 bits (67), Expect = 5.0
Identities = 11/26 (42%), Positives = 19/26 (73%), Gaps = 3/26 (11%)
Query: 362 CKCSE---TKWEPMCGENGITYVSAC 384
C+C + + ++P+CG +G+TY SAC
Sbjct: 488 CECLQACSSLYDPVCGSDGVTYGSAC 513
>gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo
sapiens]
Length = 918
Score = 30.4 bits (67), Expect = 5.0
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 18/144 (12%)
Query: 171 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE----NAKIMEMAR---D 223
A+ F K PR RED NS +++ D+ ++Q + + K++E+A
Sbjct: 187 ALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEIANYVDK 246
Query: 224 FLPSLK---NLFGNPVY-FLYLC-TSTVQFNSLFGMVTYKPKYIEQQYGQSS------SR 272
F SL L G V+ +C S +++L+ ++++ K + Q+Y ++ S
Sbjct: 247 FYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSF 306
Query: 273 ANFVIGLINIPAVALGIFSGGIVM 296
IGL + A+ SGG+ M
Sbjct: 307 HGTTIGLAPLMAMCSVYQSGGVNM 330
>gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor
[Homo sapiens]
Length = 1338
Score = 30.0 bits (66), Expect = 6.5
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 373 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 432
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 433 FLYFLVISVI 442
+Y + +I
Sbjct: 137 EMYSEIPEII 146
>gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor
[Homo sapiens]
Length = 687
Score = 30.0 bits (66), Expect = 6.5
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 373 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 432
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 433 FLYFLVISVI 442
+Y + +I
Sbjct: 137 EMYSEIPEII 146
>gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor
[Homo sapiens]
Length = 541
Score = 30.0 bits (66), Expect = 6.5
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 373 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 432
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 433 FLYFLVISVI 442
+Y + +I
Sbjct: 137 EMYSEIPEII 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,241,486
Number of Sequences: 37866
Number of extensions: 1052072
Number of successful extensions: 2434
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2321
Number of HSP's gapped (non-prelim): 54
length of query: 612
length of database: 18,247,518
effective HSP length: 108
effective length of query: 504
effective length of database: 14,157,990
effective search space: 7135626960
effective search space used: 7135626960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.