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Search of human proteins with 22547184
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22547184 transient receptor potential cation channel,
subfamily V, member 4 isoform a [Homo sapiens]
(871 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22547184 transient receptor potential cation channel, subfami... 1769 0.0
gi|22547180 transient receptor potential cation channel, subfami... 874 0.0
gi|74315354 transient receptor potential cation channel, subfami... 685 0.0
gi|74315352 transient receptor potential cation channel, subfami... 685 0.0
gi|74315350 transient receptor potential cation channel, subfami... 685 0.0
gi|74315348 transient receptor potential cation channel, subfami... 685 0.0
gi|20127551 transient receptor potential cation channel, subfami... 554 e-157
gi|21735483 transient receptor potential cation channel, subfami... 540 e-153
gi|21314682 transient receptor potential cation channel, subfami... 270 3e-72
gi|17505200 transient receptor potential cation channel, subfami... 266 5e-71
gi|116534990 ankyrin-like protein 1 [Homo sapiens] 63 1e-09
gi|11225266 transient receptor potential cation channel, subfami... 58 3e-08
gi|4507689 transient receptor potential cation channel, subfamil... 48 5e-05
gi|109689695 transient receptor potential cation channel, subfam... 47 8e-05
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 42 0.003
gi|9966865 transient receptor potential cation channel, subfamil... 41 0.004
gi|169216484 PREDICTED: similar to transient receptor potential ... 41 0.006
gi|67906195 ankyrin repeat and sterile alpha motif domain contai... 40 0.012
gi|194733735 transient receptor potential cation channel, subfam... 39 0.021
gi|4507687 transient receptor potential cation channel, subfamil... 39 0.021
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 39 0.027
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 39 0.027
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 39 0.027
gi|5730102 transient receptor potential cation channel, subfamil... 38 0.036
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 38 0.036
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 38 0.036
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 38 0.036
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 38 0.036
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 38 0.036
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 38 0.036
>gi|22547184 transient receptor potential cation channel, subfamily
V, member 4 isoform a [Homo sapiens]
Length = 871
Score = 1769 bits (4581), Expect = 0.0
Identities = 871/871 (100%), Positives = 871/871 (100%)
Query: 1 MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGP 60
MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGP
Sbjct: 1 MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGP 60
Query: 61 GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDN 120
GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDN
Sbjct: 61 GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDN 120
Query: 121 KRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRL 180
KRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRL
Sbjct: 121 KRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRL 180
Query: 181 TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT 240
TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT
Sbjct: 181 TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT 240
Query: 241 ALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI 300
ALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI
Sbjct: 241 ALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI 300
Query: 301 VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDS 360
VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDS
Sbjct: 301 VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDS 360
Query: 361 NLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYD 420
NLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYD
Sbjct: 361 NLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYD 420
Query: 421 LSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLC 480
LSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLC
Sbjct: 421 LSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLC 480
Query: 481 AMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGV 540
AMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGV
Sbjct: 481 AMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGV 540
Query: 541 NSLFIDGSFQLLYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTG 600
NSLFIDGSFQLLYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTG
Sbjct: 541 NSLFIDGSFQLLYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTG 600
Query: 601 TYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSC 660
TYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSC
Sbjct: 601 TYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSC 660
Query: 661 RDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGE 720
RDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGE
Sbjct: 661 RDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGE 720
Query: 721 TVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRV 780
TVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRV
Sbjct: 721 TVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRV 780
Query: 781 DEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDE 840
DEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDE
Sbjct: 781 DEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDE 840
Query: 841 VVVPLDSMGNPRCDGHQQGYPRKWRTDDAPL 871
VVVPLDSMGNPRCDGHQQGYPRKWRTDDAPL
Sbjct: 841 VVVPLDSMGNPRCDGHQQGYPRKWRTDDAPL 871
>gi|22547180 transient receptor potential cation channel, subfamily
V, member 4 isoform b [Homo sapiens]
Length = 811
Score = 874 bits (2258), Expect = 0.0
Identities = 431/440 (97%), Positives = 432/440 (98%)
Query: 432 SVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYY 491
S L + KI NRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYY
Sbjct: 372 SPLMMAAKTGKIGNRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYY 431
Query: 492 QPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQL 551
QPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQL
Sbjct: 432 QPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQL 491
Query: 552 LYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILF 611
LYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILF
Sbjct: 492 LYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILF 551
Query: 612 KDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLL 671
KDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLL
Sbjct: 552 KDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLL 611
Query: 672 DLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKH 731
DLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKH
Sbjct: 612 DLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKH 671
Query: 732 IWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQN 791
IWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQN
Sbjct: 672 IWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQN 731
Query: 792 LGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDEVVVPLDSMGNP 851
LGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDEVVVPLDSMGNP
Sbjct: 732 LGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDEVVVPLDSMGNP 791
Query: 852 RCDGHQQGYPRKWRTDDAPL 871
RCDGHQQGYPRKWRTDDAPL
Sbjct: 792 RCDGHQQGYPRKWRTDDAPL 811
Score = 786 bits (2031), Expect = 0.0
Identities = 390/406 (96%), Positives = 393/406 (96%)
Query: 1 MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGP 60
MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGP
Sbjct: 1 MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGP 60
Query: 61 GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDN 120
GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDN
Sbjct: 61 GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDN 120
Query: 121 KRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRL 180
KRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRL
Sbjct: 121 KRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRL 180
Query: 181 TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT 240
TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT
Sbjct: 181 TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT 240
Query: 241 ALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI 300
ALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI
Sbjct: 241 ALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI 300
Query: 301 VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDS 360
VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDS
Sbjct: 301 VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDS 360
Query: 361 NLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSRKF 406
NLEAVLNNDGLSPLMMAAKTGKIG ++ E +E R RKF
Sbjct: 361 NLEAVLNNDGLSPLMMAAKTGKIGNRHEMLAVEPINELLRDKWRKF 406
>gi|74315354 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 685 bits (1768), Expect = 0.0
Identities = 351/709 (49%), Positives = 499/709 (70%), Gaps = 18/709 (2%)
Query: 146 LKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNG 205
L++++R +F+ V++ + DL+ LL FL KK LTD EF++P TGKTCL KA+LNL +G
Sbjct: 110 LRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDG 169
Query: 206 RNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVH 265
+N TIP+LL+IA +T +++E +N+ + D YY+GQTALHIAIERR V LLV GADV
Sbjct: 170 QNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQ 229
Query: 266 AQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVL 325
A A G FF+ FYFGELPLSLAACTNQ IV +L +N + AD+ +DS GNTVL
Sbjct: 230 AAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVL 289
Query: 326 HALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGI 385
HALV +ADNT +NTKFVT MY+ +L+ A+L P LE + N G++PL +AA TGKIG+
Sbjct: 290 HALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGV 349
Query: 386 FQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVY-NSKIE 444
+I++RE+ + + RHLSRKF +WAYGPV+SSLYDLS +DTC E+ SVLE++ Y +S+
Sbjct: 350 LAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETP 408
Query: 445 NRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRT 504
NRH+ML VEP+N LL+DKW +F FY N + Y M+IFT+ AYY+P++G PP+
Sbjct: 409 NRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEK 468
Query: 505 TVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSA 564
T DY R+ GE++++ GV FFF I+ F+++ P + +LF+D ++L+F+ S+ ++ +
Sbjct: 469 TGDYFRVTGEILSVLGGVYFFFRGIQ-YFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATV 527
Query: 565 ALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLF 624
LY + ++ Y+A MVF+L LGW N LY+TRG + G Y++MI+K++ +DL RF+ VY++F
Sbjct: 528 VLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVF 587
Query: 625 MIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSET-----FSTFLLDLFKLTIG 679
+ G+++A+V+L+ N + +E ++ P+CR ++ +ST L+LFK TIG
Sbjct: 588 LFGFSTAVVTLIEDGKNDSLPSESTSHRW--RGPACRPPDSSYNSLYST-CLELFKFTIG 644
Query: 680 MGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWAT 739
MGDLE + + VFIILL+ Y+ILT++LLLNMLIALMGETV ++++ESK+IWKLQ A
Sbjct: 645 MGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAI 704
Query: 740 TILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDP 799
TILD E+SF +RKAFRSG+++ VG + DG D RWCFRVDEVNW+ WN N+GIINEDP
Sbjct: 705 TILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDP 764
Query: 800 GKNE-TYQYYGFSHTVGRLRRDRWS--SVVPRVVELN----KNSNPDEV 841
G E + FS R+ W ++VP + E + +++ P+EV
Sbjct: 765 GNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEV 813
>gi|74315352 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 685 bits (1768), Expect = 0.0
Identities = 351/709 (49%), Positives = 499/709 (70%), Gaps = 18/709 (2%)
Query: 146 LKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNG 205
L++++R +F+ V++ + DL+ LL FL KK LTD EF++P TGKTCL KA+LNL +G
Sbjct: 110 LRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDG 169
Query: 206 RNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVH 265
+N TIP+LL+IA +T +++E +N+ + D YY+GQTALHIAIERR V LLV GADV
Sbjct: 170 QNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQ 229
Query: 266 AQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVL 325
A A G FF+ FYFGELPLSLAACTNQ IV +L +N + AD+ +DS GNTVL
Sbjct: 230 AAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVL 289
Query: 326 HALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGI 385
HALV +ADNT +NTKFVT MY+ +L+ A+L P LE + N G++PL +AA TGKIG+
Sbjct: 290 HALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGV 349
Query: 386 FQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVY-NSKIE 444
+I++RE+ + + RHLSRKF +WAYGPV+SSLYDLS +DTC E+ SVLE++ Y +S+
Sbjct: 350 LAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETP 408
Query: 445 NRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRT 504
NRH+ML VEP+N LL+DKW +F FY N + Y M+IFT+ AYY+P++G PP+
Sbjct: 409 NRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEK 468
Query: 505 TVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSA 564
T DY R+ GE++++ GV FFF I+ F+++ P + +LF+D ++L+F+ S+ ++ +
Sbjct: 469 TGDYFRVTGEILSVLGGVYFFFRGIQ-YFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATV 527
Query: 565 ALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLF 624
LY + ++ Y+A MVF+L LGW N LY+TRG + G Y++MI+K++ +DL RF+ VY++F
Sbjct: 528 VLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVF 587
Query: 625 MIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSET-----FSTFLLDLFKLTIG 679
+ G+++A+V+L+ N + +E ++ P+CR ++ +ST L+LFK TIG
Sbjct: 588 LFGFSTAVVTLIEDGKNDSLPSESTSHRW--RGPACRPPDSSYNSLYST-CLELFKFTIG 644
Query: 680 MGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWAT 739
MGDLE + + VFIILL+ Y+ILT++LLLNMLIALMGETV ++++ESK+IWKLQ A
Sbjct: 645 MGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAI 704
Query: 740 TILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDP 799
TILD E+SF +RKAFRSG+++ VG + DG D RWCFRVDEVNW+ WN N+GIINEDP
Sbjct: 705 TILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDP 764
Query: 800 GKNE-TYQYYGFSHTVGRLRRDRWS--SVVPRVVELN----KNSNPDEV 841
G E + FS R+ W ++VP + E + +++ P+EV
Sbjct: 765 GNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEV 813
>gi|74315350 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 685 bits (1768), Expect = 0.0
Identities = 351/709 (49%), Positives = 499/709 (70%), Gaps = 18/709 (2%)
Query: 146 LKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNG 205
L++++R +F+ V++ + DL+ LL FL KK LTD EF++P TGKTCL KA+LNL +G
Sbjct: 110 LRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDG 169
Query: 206 RNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVH 265
+N TIP+LL+IA +T +++E +N+ + D YY+GQTALHIAIERR V LLV GADV
Sbjct: 170 QNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQ 229
Query: 266 AQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVL 325
A A G FF+ FYFGELPLSLAACTNQ IV +L +N + AD+ +DS GNTVL
Sbjct: 230 AAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVL 289
Query: 326 HALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGI 385
HALV +ADNT +NTKFVT MY+ +L+ A+L P LE + N G++PL +AA TGKIG+
Sbjct: 290 HALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGV 349
Query: 386 FQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVY-NSKIE 444
+I++RE+ + + RHLSRKF +WAYGPV+SSLYDLS +DTC E+ SVLE++ Y +S+
Sbjct: 350 LAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETP 408
Query: 445 NRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRT 504
NRH+ML VEP+N LL+DKW +F FY N + Y M+IFT+ AYY+P++G PP+
Sbjct: 409 NRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEK 468
Query: 505 TVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSA 564
T DY R+ GE++++ GV FFF I+ F+++ P + +LF+D ++L+F+ S+ ++ +
Sbjct: 469 TGDYFRVTGEILSVLGGVYFFFRGIQ-YFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATV 527
Query: 565 ALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLF 624
LY + ++ Y+A MVF+L LGW N LY+TRG + G Y++MI+K++ +DL RF+ VY++F
Sbjct: 528 VLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVF 587
Query: 625 MIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSET-----FSTFLLDLFKLTIG 679
+ G+++A+V+L+ N + +E ++ P+CR ++ +ST L+LFK TIG
Sbjct: 588 LFGFSTAVVTLIEDGKNDSLPSESTSHRW--RGPACRPPDSSYNSLYST-CLELFKFTIG 644
Query: 680 MGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWAT 739
MGDLE + + VFIILL+ Y+ILT++LLLNMLIALMGETV ++++ESK+IWKLQ A
Sbjct: 645 MGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAI 704
Query: 740 TILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDP 799
TILD E+SF +RKAFRSG+++ VG + DG D RWCFRVDEVNW+ WN N+GIINEDP
Sbjct: 705 TILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDP 764
Query: 800 GKNE-TYQYYGFSHTVGRLRRDRWS--SVVPRVVELN----KNSNPDEV 841
G E + FS R+ W ++VP + E + +++ P+EV
Sbjct: 765 GNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEV 813
>gi|74315348 transient receptor potential cation channel, subfamily
V, member 1 [Homo sapiens]
Length = 839
Score = 685 bits (1768), Expect = 0.0
Identities = 351/709 (49%), Positives = 499/709 (70%), Gaps = 18/709 (2%)
Query: 146 LKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNG 205
L++++R +F+ V++ + DL+ LL FL KK LTD EF++P TGKTCL KA+LNL +G
Sbjct: 110 LRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDG 169
Query: 206 RNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVH 265
+N TIP+LL+IA +T +++E +N+ + D YY+GQTALHIAIERR V LLV GADV
Sbjct: 170 QNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQ 229
Query: 266 AQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVL 325
A A G FF+ FYFGELPLSLAACTNQ IV +L +N + AD+ +DS GNTVL
Sbjct: 230 AAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVL 289
Query: 326 HALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGI 385
HALV +ADNT +NTKFVT MY+ +L+ A+L P LE + N G++PL +AA TGKIG+
Sbjct: 290 HALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGV 349
Query: 386 FQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVY-NSKIE 444
+I++RE+ + + RHLSRKF +WAYGPV+SSLYDLS +DTC E+ SVLE++ Y +S+
Sbjct: 350 LAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETP 408
Query: 445 NRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRT 504
NRH+ML VEP+N LL+DKW +F FY N + Y M+IFT+ AYY+P++G PP+
Sbjct: 409 NRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEK 468
Query: 505 TVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSA 564
T DY R+ GE++++ GV FFF I+ F+++ P + +LF+D ++L+F+ S+ ++ +
Sbjct: 469 TGDYFRVTGEILSVLGGVYFFFRGIQ-YFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATV 527
Query: 565 ALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLF 624
LY + ++ Y+A MVF+L LGW N LY+TRG + G Y++MI+K++ +DL RF+ VY++F
Sbjct: 528 VLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVF 587
Query: 625 MIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSET-----FSTFLLDLFKLTIG 679
+ G+++A+V+L+ N + +E ++ P+CR ++ +ST L+LFK TIG
Sbjct: 588 LFGFSTAVVTLIEDGKNDSLPSESTSHRW--RGPACRPPDSSYNSLYST-CLELFKFTIG 644
Query: 680 MGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWAT 739
MGDLE + + VFIILL+ Y+ILT++LLLNMLIALMGETV ++++ESK+IWKLQ A
Sbjct: 645 MGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAI 704
Query: 740 TILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDP 799
TILD E+SF +RKAFRSG+++ VG + DG D RWCFRVDEVNW+ WN N+GIINEDP
Sbjct: 705 TILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDP 764
Query: 800 GKNE-TYQYYGFSHTVGRLRRDRWS--SVVPRVVELN----KNSNPDEV 841
G E + FS R+ W ++VP + E + +++ P+EV
Sbjct: 765 GNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEV 813
>gi|20127551 transient receptor potential cation channel, subfamily
V, member 2 [Homo sapiens]
Length = 764
Score = 554 bits (1428), Expect = e-157
Identities = 314/669 (46%), Positives = 421/669 (62%), Gaps = 17/669 (2%)
Query: 139 APQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKA 198
A QP P F+R LF+ VSRG DL GL +L K LTD E+ E STGKTCL KA
Sbjct: 66 ASQPDP--NRFDRDRLFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKA 123
Query: 199 LLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLV 258
+LNL +G N I LL I +GN + +N+ D YYRG +ALHIAIE+R V+LLV
Sbjct: 124 VLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLV 183
Query: 259 AQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQD 318
GA+VHA+A GRFFQ K +G FYFGELPLSLAACT Q +V+YL ENPH+ A ++ D
Sbjct: 184 ENGANVHARACGRFFQ-KGQGTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATD 242
Query: 319 SRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAA 378
S+GNTVLHALV I+DN+ EN VT MYD LL ARL P LE + N L+PL +AA
Sbjct: 243 SQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAA 302
Query: 379 KTGKIGIFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILV 438
K GKI IF+HI++RE + HLSRKF +W YGPV SLYDL+S+D+C EE SVLEI+
Sbjct: 303 KEGKIEIFRHILQREFS--GLSHLSRKFTEWCYGPVRVSLYDLASVDSC-EENSVLEIIA 359
Query: 439 YNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPL--EG 496
++ K +RH M+ +EP+N+LL+ KW F++N + L M IFT AY+QP +
Sbjct: 360 FHCKSPHRHRMVVLEPLNKLLQAKWDLL-IPKFFLNFLCNLIYMFIFTAVAYHQPTLKKQ 418
Query: 497 TPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIY 556
P+ + + L G ++ L G+ + F ++ + FID F++L+
Sbjct: 419 AAPHLKAEVGNSMLLTGHILILLGGIYLLVGQLW-YFWRRHVFIWISFIDSYFEILFLFQ 477
Query: 557 SVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFR 616
++L +VS L IE YL ++V ALVLGW+N LY+TRG + TG YS+MIQK++ +DL R
Sbjct: 478 ALLTVVSQVLCFLAIEWYLPLLVSALVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLR 537
Query: 617 FLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTF------L 670
FLL+YL+F+ G+A ALVSL + +V D + +
Sbjct: 538 FLLIYLVFLFGFAVALVSLSQEAWRPEAPTGPNATESVQPMEGQEDEGNGAQYRGILEAS 597
Query: 671 LDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESK 730
L+LFK TIGMG+L + + ++LL+ Y++LT++LLLNMLIALM ETV V+ +S
Sbjct: 598 LELFKFTIGMGELAFQEQLHFRGMVLLLLLAYVLLTYILLLNMLIALMSETVNSVATDSW 657
Query: 731 HIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQ 790
IWKLQ A ++L++E + + RK R+G M+TVG DG+PD RWCFRV+EVNW+ W Q
Sbjct: 658 SIWKLQKAISVLEMENGY-WWCRKKQRAGVMLTVGTKPDGSPDERWCFRVEEVNWASWEQ 716
Query: 791 NLGIINEDP 799
L + EDP
Sbjct: 717 TLPTLCEDP 725
>gi|21735483 transient receptor potential cation channel, subfamily
V, member 3 [Homo sapiens]
Length = 790
Score = 540 bits (1391), Expect = e-153
Identities = 297/658 (45%), Positives = 413/658 (62%), Gaps = 37/658 (5%)
Query: 154 LFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFRE--------PSTGKTCLPKALLNLSNG 205
+F VS G +L LL L +R DE+ + TGKTCL KALLN++
Sbjct: 123 IFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNINPN 182
Query: 206 RNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVH 265
+ + +LL AE + FIN+ + + Y GQTAL+IAIERR LL+A GADV+
Sbjct: 183 TKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVN 242
Query: 266 AQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVL 325
A A+G FF PK + FYFGE PL+LAACTNQP IV L E H++ D+ +DSRGN +L
Sbjct: 243 AHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLME--HEQTDITSRDSRGNNIL 300
Query: 326 HALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGI 385
HALV +A++ + FV +MYD++LL+ LE NNDGL+PL +AAK GK I
Sbjct: 301 HALVTVAEDFKTQNDFVKRMYDMILLRSGNW----ELETTRNNDGLTPLQLAAKMGKAEI 356
Query: 386 FQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVYNSKIEN 445
++I+ RE+ ++ R LSRKF DWAYGPV SSLYDL+++DT + SVLEI VYN+ I+N
Sbjct: 357 LKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDN-SVLEITVYNTNIDN 415
Query: 446 RHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTP-PYPYRT 504
RHEML +EP++ LL KW+KF F+++ Y + TL +YY+P E P+P
Sbjct: 416 RHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLAL 475
Query: 505 T--VDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIV 562
T + +L+L G + L + +F+ + + S+ D F ++FI +VLVI+
Sbjct: 476 THKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVIL 535
Query: 563 SAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYL 622
S LYL + YLA +V A+ LGW N LY+TRG + G YS+MIQK++ D+ +FL VY+
Sbjct: 536 SVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYI 595
Query: 623 LFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGD 682
+F++G+ AL SL+ C +D +C+ +Y S FS +L+LFKLTIG+GD
Sbjct: 596 VFLLGFGVALASLIEKCP------KDNKDCS--SYGS------FSDAVLELFKLTIGLGD 641
Query: 683 LEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTIL 742
L + ++KYP++F+ LL+TY+ILTFVLLLNMLIALMGETV VSKES+ IW+LQ A TIL
Sbjct: 642 LNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTIL 701
Query: 743 DIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDPG 800
+ E+ P +LR FR GE+ V + D R C R++EV W+ W ++ +NEDPG
Sbjct: 702 EFEKMLPEWLRSRFRMGELCKVAED-----DFRLCLRINEVKWTEWKTHVSFLNEDPG 754
>gi|21314682 transient receptor potential cation channel, subfamily
V, member 6 [Homo sapiens]
Length = 725
Score = 270 bits (691), Expect = 3e-72
Identities = 183/546 (33%), Positives = 278/546 (50%), Gaps = 61/546 (11%)
Query: 225 EFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF 284
E + P Y GQTALHIA+ + + V L+A+ A V A+A G F+ + YF
Sbjct: 104 ELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFR-RSPCNLIYF 162
Query: 285 GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTK 344
GE PLS AAC N IV L E+ AD+R QDS GNTVLH L+ + N F +
Sbjct: 163 GEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQ 214
Query: 345 MYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSR 404
MY+LLL L+ V N+ GL+P +A G +FQH++++ R
Sbjct: 215 MYNLLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------R 263
Query: 405 KFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWR 464
K W YGP+ S+LYDL+ +D+ G+E S+LE+++ K E R ++L P+ EL+ KW+
Sbjct: 264 KHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWK 322
Query: 465 KFGAVSFYINVVSYLCAMVIFTLTAYYQPLEG-----TPPYP------------YRTTVD 507
++G F + YL ++ FT+ Y+PL+ T P Y T D
Sbjct: 323 RYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKD 382
Query: 508 YLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIVS 563
+RL GE++T+ ++ + D+F GV F + G F +L Y+ +V+V+
Sbjct: 383 DIRLVGELVTVIGAIIILLVEVPDIFRM---GVTRFFGQTILGGPFHVLIITYAFMVLVT 439
Query: 564 AALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLL 623
+ L + M FALVLGW N +YF RG ++ G ++IMIQK++F DL RF + +
Sbjct: 440 MVMRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAV 499
Query: 624 FMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDL 683
++G+ASA + + + YP FSTF +LF LTI G
Sbjct: 500 VILGFASAFYIIFQ-------TEDPEELGHFYDYPMA----LFSTF--ELF-LTIIDGPA 545
Query: 684 EMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILD 743
+ P ++ I + I+ +L+LN+LIA+MG+T +V+ E +W+ Q T +
Sbjct: 546 NY--NVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVM 603
Query: 744 IERSFP 749
+ER P
Sbjct: 604 LERKLP 609
>gi|17505200 transient receptor potential cation channel, subfamily
V, member 5 [Homo sapiens]
Length = 729
Score = 266 bits (681), Expect = 5e-71
Identities = 192/581 (33%), Positives = 286/581 (49%), Gaps = 68/581 (11%)
Query: 225 EFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF 284
E + P + GQTALHIA+ + + V L+ + A V A+A G F+ + YF
Sbjct: 104 ELVFEPTTCEAFAGQTALHIAVVNQNVNLVRALLTRRASVSARATGTAFR-RSPRNLIYF 162
Query: 285 GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTK 344
GE PLS AAC N IV L E+ AD+R QDS GNTVLH L+ + N F +
Sbjct: 163 GEHPLSFAACVNSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQ 214
Query: 345 MYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSR 404
MY+LLL L+ V N+ GL+P +A G +FQH++++ RH+
Sbjct: 215 MYNLLLSYDGHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHLMQKR------RHIQ- 267
Query: 405 KFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWR 464
W YGP+ S LYDL+ +D+ GEE S LE++V + K E R ++L P+ EL+ KW
Sbjct: 268 ----WTYGPLTSILYDLTEIDSWGEELSFLELVVSSDKREAR-QILEQTPVKELVSFKWN 322
Query: 465 KFGAVSFYINVVSYLCAMVIFTLTAYYQPLE---GTPPYP--------------YRTTVD 507
K+G F I YL M+ FT Y+PL+ G + Y T D
Sbjct: 323 KYGRPYFCILAALYLLYMICFTTCCVYRPLKFRGGNRTHSRDITILQQKLLQEAYETRED 382
Query: 508 YLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIVS 563
+RL GE++++ V+ I D+F G + F + G F ++ Y+ LV+V+
Sbjct: 383 IIRLVGELVSIVGAVIILLLEIPDIFRV---GASRYFGKTILGGPFHVIIITYASLVLVT 439
Query: 564 AALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLL 623
+ L + M FALVLGW + +YFTRG ++ G ++IMIQK++F DL RF + +
Sbjct: 440 MVMRLTNTNGEVVPMSFALVLGWCSVMYFTRGFQMLGPFTIMIQKMIFGDLMRFCWLMAV 499
Query: 624 FMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDL 683
++G+ASA + ED T S + L F+L + + D
Sbjct: 500 VILGFASAFYIIFQ--------TEDPT--------SLGQFYDYPMALFTTFELFLTVIDA 543
Query: 684 EMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILD 743
P +F I+ + I+ +L+LN+ IA+MG+T +V++E +W+ Q T +
Sbjct: 544 PANYDVDLPFMFSIVNFAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVM 603
Query: 744 IERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVN 784
+ER P L RSG + G D RW RV+ N
Sbjct: 604 LERKLPRCLWP--RSG----ICGCEFGLGD-RWFLRVENHN 637
>gi|116534990 ankyrin-like protein 1 [Homo sapiens]
Length = 1119
Score = 62.8 bits (151), Expect = 1e-09
Identities = 85/364 (23%), Positives = 152/364 (41%), Gaps = 45/364 (12%)
Query: 425 DTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVI 484
D E + L +V N NR E+L E L KW +G + +N+ SY ++
Sbjct: 677 DVIYEPLTALNAMVQN----NRIELLNHPVCKEYLLMKWLAYGFRAHMMNLGSYCLGLIP 732
Query: 485 FT-LTAYYQP---------LEGTPPYP--YRTTVDYLRLAGEVITLFTGVLFFFTNIKDL 532
T L +P + T + TT YL ++ + + + +
Sbjct: 733 MTILVVNIKPGMAFNSTGIINETSDHSEILDTTNSYLIKTCMILVFLSSIFGYCKEAGQI 792
Query: 533 FMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSAALYLAGIEAYLAVM--VFALVLGWMNAL 590
F +K + F+D S L + IY+ +I L++ I A+L A+ WMN L
Sbjct: 793 FQQK----RNYFMDISNVLEWIIYTTGIIFVLPLFVE-IPAHLQWQCGAIAVYFYWMNFL 847
Query: 591 YFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQT 650
+ + + G + +M++ IL K L R +V++ ++ + + LLN +D
Sbjct: 848 LYLQRFENCGIFIVMLEVIL-KTLLRSTVVFIFLLLAFGLSFYILLNL--------QDPF 898
Query: 651 NCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLL 710
+ P +TFS L D+ + + + +PV+ LV++ I ++L
Sbjct: 899 SS-----PLLSIIQTFSMMLGDI-NYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVL 952
Query: 711 LNMLIALMGETVGQVSKESKHIWKLQWATTI---LDIERSFPV-FLRKAFRSGEMVTVGK 766
+N+LI L VG +++ KH + A + +E+ P+ FLRK + +V K
Sbjct: 953 MNLLIGL---AVGDIAEVQKHASLKRIAMQVELHTSLEKKLPLWFLRKVDQKSTIVYPNK 1009
Query: 767 SSDG 770
G
Sbjct: 1010 PRSG 1013
>gi|11225266 transient receptor potential cation channel, subfamily M,
member 5 [Homo sapiens]
Length = 1165
Score = 58.2 bits (139), Expect = 3e-08
Identities = 83/347 (23%), Positives = 146/347 (42%), Gaps = 31/347 (8%)
Query: 413 PVYSSLYDLSSLDTCGEEASVLEILVYNSKIENRHEMLAVE----PINELLRDKWRKFGA 468
P+ + L DL LD+ E S L L S++E E + P L +WRKF
Sbjct: 672 PLRTGLEDLQDLDSLDTEKSPLYGL--QSRVEELVEAPRAQGDRGPRAVFLLTRWRKFWG 729
Query: 469 VS---FYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLF- 524
F NVV Y + +FT Y L P P + + L V TL +
Sbjct: 730 APVTVFLGNVVMYFAFLFLFT----YVLLVDFRPPPQGPSGPEVTLYFWVFTLVLEEIRQ 785
Query: 525 -FFTNIKDLFMKKCPGVNSLFIDGSFQL--LYFIYSVLVIVSAALYLAGIEAYLAVMVFA 581
FFT+ +KK +L++ ++ + I+ +V V+ + + EA V+
Sbjct: 786 GFFTDEDTHLVKKF----TLYVGDNWNKCDMVAIFLFIVGVTCRMLPSAFEAGRTVLAMD 841
Query: 582 LVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCAN 641
++ + ++ K G I++++++ KD+F FL ++++ Y +LL+P
Sbjct: 842 FMVFTLRLIHIFAIHKQLGPKIIVVERMM-KDVFFFLFFLSVWLVAYGVTTQALLHPHDG 900
Query: 642 MKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVF-----I 696
+ V P + +D ++ L + S P ++ I
Sbjct: 901 ----RLEWIFRRVLYRPYLQIFGQIPLDEIDEARVNCSTHPLLLEDSPSCPSLYANWLVI 956
Query: 697 ILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILD 743
+LLVT++++T VLL+N+LIA+ T V + WK Q I++
Sbjct: 957 LLLVTFLLVTNVLLMNLLIAMFSYTFQVVQGNADMFWKFQRYNLIVE 1003
>gi|4507689 transient receptor potential cation channel, subfamily M,
member 2 [Homo sapiens]
Length = 1503
Score = 47.8 bits (112), Expect = 5e-05
Identities = 70/288 (24%), Positives = 117/288 (40%), Gaps = 38/288 (13%)
Query: 469 VSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTN 528
V F++N++SY + +F AY ++ P + YL L V + F+
Sbjct: 797 VVFHLNILSYFAFLCLF---AYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQL--FYDP 851
Query: 529 IKDLFMKKCPGVNSLF---IDGSFQLLYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLG 585
+ MKK S F +D LL+ ++ A LY + L ++F L L
Sbjct: 852 DECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILSLDFILFCLRLM 911
Query: 586 WMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCANMKVC 645
+ + T G K I+I K + KD+F FL + ++++ + A ++L +
Sbjct: 912 HIFTISKTLGPK------IIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAIL-------IH 958
Query: 646 NEDQTN-----CTVPTY-------PSCRDSETF-----STFLLDLFKLTIGMGDLEMLSS 688
NE + + +Y P D F S D +K D
Sbjct: 959 NERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRP 1018
Query: 689 TKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQ 736
+ ++LL Y++ T +LLLN+LIA+ T QV + + IWK Q
Sbjct: 1019 AFPEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQ 1066
>gi|109689695 transient receptor potential cation channel, subfamily
M, member 8 [Homo sapiens]
Length = 1104
Score = 47.0 bits (110), Expect = 8e-05
Identities = 66/287 (22%), Positives = 128/287 (44%), Gaps = 44/287 (15%)
Query: 469 VSFYINVVSYLCAMVIFTLTAYYQPLE----GTPPYPYRTTVDYLRLAGEVITLFTGVLF 524
V F NVV Y+ +++F AY ++ PP ++ ++ EV + +
Sbjct: 736 VVFSWNVVFYIAFLLLF---AYVLLMDFHSVPHPPELVLYSLVFVLFCDEVRQWYVNGVN 792
Query: 525 FFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIV----SAALYLAGIEAYLAVMVF 580
+FT++ ++ + L YFI ++ + ++LY + L ++F
Sbjct: 793 YFTDLWNVM-------------DTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIF 839
Query: 581 ALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCA 640
L L ++ +R L G IM+Q++L D+F FL ++ ++M+ + A +L
Sbjct: 840 TLRL--IHIFTVSRNL---GPKIIMLQRMLI-DVFFFLFLFAVWMVAFGVARQGILRQNE 893
Query: 641 N-----MKVCNEDQTNCTVPTYPSCRDSETFS----TFLLDLFK-LTIGMGDLEMLSSTK 690
+ + PS D T+ TF + K L + +L+ + +
Sbjct: 894 QRWRWIFRSVIYEPYLAMFGQVPSDVDGTTYDFAHCTFTGNESKPLCV---ELDEHNLPR 950
Query: 691 YPV-VFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQ 736
+P + I L+ Y++ T +LL+N+L+A+ G TVG V + + +WK Q
Sbjct: 951 FPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKFQ 997
>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
Length = 1050
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 30/161 (18%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
RG T LH+A ++LLV++GA V+A Y G PL LA
Sbjct: 462 RGHTPLHVAAVCGQASLIDLLVSKGAMVNATD--------------YHGATPLHLACQKG 507
Query: 297 QPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARL 356
+ L H KA QD+ GNT LH E+ YD+
Sbjct: 508 YQSVTLLLL---HYKASAEVQDNNGNTPLHLACTYG---HEDCVKALVYYDV-------- 553
Query: 357 FPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDE 397
+S + N G +PL +AA+ G G+ + +++ + E
Sbjct: 554 --ESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTE 592
>gi|9966865 transient receptor potential cation channel, subfamily
C, member 7 [Homo sapiens]
Length = 862
Score = 41.2 bits (95), Expect = 0.004
Identities = 36/160 (22%), Positives = 74/160 (46%), Gaps = 24/160 (15%)
Query: 581 ALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCA 640
A+VL + Y + G I + + + KD+F+F++++++ + + ++ + N +
Sbjct: 547 AVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAF---MIGMFNLYS 602
Query: 641 NMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSST-KYPVVFI--- 696
+ + TV E+F T +F L+ E++S KY FI
Sbjct: 603 YYRGAKYNPAFTTV--------EESFKTLFWSIFGLS------EVISVVLKYDHKFIENI 648
Query: 697 --ILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWK 734
+L Y + V+LLNMLIA++ + ++ +++ WK
Sbjct: 649 GYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWK 688
>gi|169216484 PREDICTED: similar to transient receptor potential
channel subfamily C member 6 [Homo sapiens]
Length = 304
Score = 40.8 bits (94), Expect = 0.006
Identities = 26/123 (21%), Positives = 59/123 (47%), Gaps = 11/123 (8%)
Query: 612 KDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLL 671
KD+FRF+L++++ + + + +L + ++K N T + ++TF+L
Sbjct: 145 KDIFRFMLIFIMVFVAFMIGMFNLYSYYIDVK------QNEAFTTVEESFKTLFWATFVL 198
Query: 672 DLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKH 731
K + + + + Y +L Y + ++LLNMLIA++ ++ ++ ++
Sbjct: 199 SAVKSVVINYSHKFIENIGY-----VLYGVYDVTMVIVLLNMLIAMINSSLQEIEDDADV 253
Query: 732 IWK 734
WK
Sbjct: 254 EWK 256
>gi|67906195 ankyrin repeat and sterile alpha motif domain
containing 6 [Homo sapiens]
Length = 871
Score = 39.7 bits (91), Expect = 0.012
Identities = 50/181 (27%), Positives = 77/181 (42%), Gaps = 33/181 (18%)
Query: 240 TALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPH 299
TAL AI+ + V LL+ GAD + AR G PL LAA T +
Sbjct: 193 TALMAAIQHGHEAVVRLLMEWGADPNHAART-------------VGWSPLMLAALTGRLG 239
Query: 300 IVNYLTE---NPHKKADMRRQ------DSRGNTV---LHALVAIADNTRENTK-----FV 342
+ L E NP + + + D + + L L + T E +
Sbjct: 240 VAQQLVEKGANPDHLSVLEKTAFEVALDCKHRDLVDYLDPLTTVRPKTDEEKRRPDIFHA 299
Query: 343 TKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR--EVTDEDTR 400
KM + L+K S++ V N DG +PLM+AA TG++ + Q ++ R +V +D+
Sbjct: 300 LKMGNFQLVKEIADEDPSHVNLV-NGDGATPLMLAAVTGQLALVQLLVERHADVDKQDSV 358
Query: 401 H 401
H
Sbjct: 359 H 359
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 38.9 bits (89), Expect = 0.021
Identities = 39/160 (24%), Positives = 69/160 (43%), Gaps = 24/160 (15%)
Query: 581 ALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCA 640
A+VL + Y + G I + + + KD+F+F++++++ + + L +
Sbjct: 618 AVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSYYL 676
Query: 641 NMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSST-KYPVVFI--- 696
KV N T E+F T +F L+ E+ S KY FI
Sbjct: 677 GAKV------NAAFTTV-----EESFKTLFWSIFGLS------EVTSVVLKYDHKFIENI 719
Query: 697 --ILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWK 734
+L Y + V+LLNMLIA++ + ++ +S WK
Sbjct: 720 GYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWK 759
>gi|4507687 transient receptor potential cation channel, subfamily
C, member 3 isoform b [Homo sapiens]
Length = 848
Score = 38.9 bits (89), Expect = 0.021
Identities = 39/160 (24%), Positives = 69/160 (43%), Gaps = 24/160 (15%)
Query: 581 ALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCA 640
A+VL + Y + G I + + + KD+F+F++++++ + + L +
Sbjct: 545 AVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSYYL 603
Query: 641 NMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSST-KYPVVFI--- 696
KV N T E+F T +F L+ E+ S KY FI
Sbjct: 604 GAKV------NAAFTTV-----EESFKTLFWSIFGLS------EVTSVVLKYDHKFIENI 646
Query: 697 --ILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWK 734
+L Y + V+LLNMLIA++ + ++ +S WK
Sbjct: 647 GYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWK 686
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 38.5 bits (88), Expect = 0.027
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 14/71 (19%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
+G TALHIA V++LV +GA+++AQ++ F PL +AA N
Sbjct: 75 KGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGF--------------TPLYMAAQEN 120
Query: 297 QPHIVNYLTEN 307
+V YL EN
Sbjct: 121 HIDVVKYLLEN 131
Score = 32.7 bits (73), Expect = 1.5
Identities = 38/156 (24%), Positives = 61/156 (39%), Gaps = 33/156 (21%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
RG+TALH+A V L+ GA V A+AR + PL +A+
Sbjct: 442 RGETALHMAARAGQVEVVRCLLRNGALVDARAREE--------------QTPLHIASRLG 487
Query: 297 QPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARL 356
+ IV L ++ A + G T LH + RE V + L
Sbjct: 488 KTEIVQLLLQH---MAHPDAATTNGYTPLHI------SAREGQVDVASV----------L 528
Query: 357 FPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
++ G +PL +AAK G + + + +++R
Sbjct: 529 LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 564
Score = 32.0 bits (71), Expect = 2.6
Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 34/161 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LH+A + LL+ +GA HA A+ G PL +AA NQ
Sbjct: 575 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN--------------GYTPLHIAAKKNQ 620
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLF 357
I + L + A+ +G T LH + + T M LLL K A +
Sbjct: 621 MQIASTLL---NYGAETNIVTKQGVTPLHL---------ASQEGHTDMVTLLLDKGANIH 668
Query: 358 PDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDED 398
+ GL+ L +AA+ K+ + I+ + D+D
Sbjct: 669 -------MSTKSGLTSLHLAAQEDKVNV-ADILTKHGADQD 701
Score = 30.0 bits (66), Expect = 9.7
Identities = 40/161 (24%), Positives = 66/161 (40%), Gaps = 33/161 (20%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LHIA + LL+ +GA V AR G PL +A+
Sbjct: 212 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN--------------GITPLHVASKRGN 257
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLF 357
++V L + + D + +D G T LH + ++ +LLL + A L
Sbjct: 258 TNMVKLLLDRGGQ-IDAKTRD--GLTPLHCAARSGHD---------QVVELLLERGAPLL 305
Query: 358 PDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDED 398
+ +GLSPL MAA+ + +H+++ + +D
Sbjct: 306 ARTK-------NGLSPLHMAAQGDHVECVKHLLQHKAPVDD 339
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 38.5 bits (88), Expect = 0.027
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 14/71 (19%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
+G TALHIA V++LV +GA+++AQ++ F PL +AA N
Sbjct: 96 KGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGF--------------TPLYMAAQEN 141
Query: 297 QPHIVNYLTEN 307
+V YL EN
Sbjct: 142 HIDVVKYLLEN 152
Score = 32.7 bits (73), Expect = 1.5
Identities = 38/156 (24%), Positives = 61/156 (39%), Gaps = 33/156 (21%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
RG+TALH+A V L+ GA V A+AR + PL +A+
Sbjct: 463 RGETALHMAARAGQVEVVRCLLRNGALVDARAREE--------------QTPLHIASRLG 508
Query: 297 QPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARL 356
+ IV L ++ A + G T LH + RE V + L
Sbjct: 509 KTEIVQLLLQH---MAHPDAATTNGYTPLHI------SAREGQVDVASV----------L 549
Query: 357 FPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
++ G +PL +AAK G + + + +++R
Sbjct: 550 LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585
Score = 32.0 bits (71), Expect = 2.6
Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 34/161 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LH+A + LL+ +GA HA A+ G PL +AA NQ
Sbjct: 596 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN--------------GYTPLHIAAKKNQ 641
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLF 357
I + L + A+ +G T LH + + T M LLL K A +
Sbjct: 642 MQIASTLL---NYGAETNIVTKQGVTPLHL---------ASQEGHTDMVTLLLDKGANIH 689
Query: 358 PDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDED 398
+ GL+ L +AA+ K+ + I+ + D+D
Sbjct: 690 -------MSTKSGLTSLHLAAQEDKVNV-ADILTKHGADQD 722
Score = 30.0 bits (66), Expect = 9.7
Identities = 40/161 (24%), Positives = 66/161 (40%), Gaps = 33/161 (20%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LHIA + LL+ +GA V AR G PL +A+
Sbjct: 233 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN--------------GITPLHVASKRGN 278
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLF 357
++V L + + D + +D G T LH + ++ +LLL + A L
Sbjct: 279 TNMVKLLLDRGGQ-IDAKTRD--GLTPLHCAARSGHD---------QVVELLLERGAPLL 326
Query: 358 PDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDED 398
+ +GLSPL MAA+ + +H+++ + +D
Sbjct: 327 ARTK-------NGLSPLHMAAQGDHVECVKHLLQHKAPVDD 360
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 38.5 bits (88), Expect = 0.027
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 14/71 (19%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
+G TALHIA V++LV +GA+++AQ++ F PL +AA N
Sbjct: 96 KGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGF--------------TPLYMAAQEN 141
Query: 297 QPHIVNYLTEN 307
+V YL EN
Sbjct: 142 HIDVVKYLLEN 152
Score = 32.7 bits (73), Expect = 1.5
Identities = 38/156 (24%), Positives = 61/156 (39%), Gaps = 33/156 (21%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
RG+TALH+A V L+ GA V A+AR + PL +A+
Sbjct: 463 RGETALHMAARAGQVEVVRCLLRNGALVDARAREE--------------QTPLHIASRLG 508
Query: 297 QPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARL 356
+ IV L ++ A + G T LH + RE V + L
Sbjct: 509 KTEIVQLLLQH---MAHPDAATTNGYTPLHI------SAREGQVDVASV----------L 549
Query: 357 FPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
++ G +PL +AAK G + + + +++R
Sbjct: 550 LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQR 585
Score = 32.0 bits (71), Expect = 2.6
Identities = 42/161 (26%), Positives = 64/161 (39%), Gaps = 34/161 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LH+A + LL+ +GA HA A+ G PL +AA NQ
Sbjct: 596 GLTPLHVAAHYDNQKVALLLLEKGASPHATAKN--------------GYTPLHIAAKKNQ 641
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLF 357
I + L + A+ +G T LH + + T M LLL K A +
Sbjct: 642 MQIASTLL---NYGAETNIVTKQGVTPLHL---------ASQEGHTDMVTLLLDKGANIH 689
Query: 358 PDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDED 398
+ GL+ L +AA+ K+ + I+ + D+D
Sbjct: 690 -------MSTKSGLTSLHLAAQEDKVNV-ADILTKHGADQD 722
Score = 30.0 bits (66), Expect = 9.7
Identities = 40/161 (24%), Positives = 66/161 (40%), Gaps = 33/161 (20%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LHIA + LL+ +GA V AR G PL +A+
Sbjct: 233 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN--------------GITPLHVASKRGN 278
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLF 357
++V L + + D + +D G T LH + ++ +LLL + A L
Sbjct: 279 TNMVKLLLDRGGQ-IDAKTRD--GLTPLHCAARSGHD---------QVVELLLERGAPLL 326
Query: 358 PDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDED 398
+ +GLSPL MAA+ + +H+++ + +D
Sbjct: 327 ARTK-------NGLSPLHMAAQGDHVECVKHLLQHKAPVDD 360
>gi|5730102 transient receptor potential cation channel, subfamily
C, member 6 [Homo sapiens]
Length = 931
Score = 38.1 bits (87), Expect = 0.036
Identities = 30/154 (19%), Positives = 69/154 (44%), Gaps = 12/154 (7%)
Query: 581 ALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCA 640
A+VL + Y + G I + + + KD+F+F++++++ + + + +L +
Sbjct: 602 AVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSYYI 660
Query: 641 NMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLV 700
K +++ TV E+F T +F L+ + + + +L
Sbjct: 661 GAK---QNEAFTTV--------EESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYG 709
Query: 701 TYIILTFVLLLNMLIALMGETVGQVSKESKHIWK 734
Y + ++LLNMLIA++ + ++ ++ WK
Sbjct: 710 VYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWK 743
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 38.1 bits (87), Expect = 0.036
Identities = 55/219 (25%), Positives = 84/219 (38%), Gaps = 36/219 (16%)
Query: 195 LPKALLNLSNGR-----NDTIPVLLDIAERTGNMREFINSPFRDIYY-----RGQTALHI 244
L KAL +L NG N L +A + G+++ + ++I +G TALHI
Sbjct: 58 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 117
Query: 245 AIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYL 304
A V LV GA+V+AQ++ F PL +AA N +V +L
Sbjct: 118 AALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQENHLEVVKFL 163
Query: 305 TENPHKK----------ADMRRQDSRGNTVLHAL-VAIADNTRENTKFVTKMYDLLLLKC 353
EN + + Q N V H + R + D
Sbjct: 164 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAA 223
Query: 354 ARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
L D N + VL+ G +PL +AA + + Q ++ R
Sbjct: 224 VLLQNDPNPD-VLSKTGFTPLHIAAHYENLNVAQLLLNR 261
Score = 32.3 bits (72), Expect = 2.0
Identities = 43/193 (22%), Positives = 66/193 (34%), Gaps = 41/193 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF------------- 284
G T LHIA ++ +ELL+ GA + A P +
Sbjct: 404 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL-TPLHVASFMGHLPIVKNLLQRGAS 462
Query: 285 -------GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHA--------LV 329
E PL +AA + YL +N KA + + T LH +V
Sbjct: 463 PNVSNVKVETPLHMAARAGHTEVAKYLLQN---KAKVNAKAKDDQTPLHCAARIGHTNMV 519
Query: 330 AIADNTRENTKFVTKMYDLLLLKCAR---------LFPDSNLEAVLNNDGLSPLMMAAKT 380
+ N T L AR L +A + G +PL +AAK
Sbjct: 520 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKY 579
Query: 381 GKIGIFQHIIRRE 393
GK+ + + ++ R+
Sbjct: 580 GKVRVAELLLERD 592
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 38.1 bits (87), Expect = 0.036
Identities = 55/219 (25%), Positives = 84/219 (38%), Gaps = 36/219 (16%)
Query: 195 LPKALLNLSNGR-----NDTIPVLLDIAERTGNMREFINSPFRDIYY-----RGQTALHI 244
L KAL +L NG N L +A + G+++ + ++I +G TALHI
Sbjct: 25 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 84
Query: 245 AIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYL 304
A V LV GA+V+AQ++ F PL +AA N +V +L
Sbjct: 85 AALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQENHLEVVKFL 130
Query: 305 TENPHKK----------ADMRRQDSRGNTVLHAL-VAIADNTRENTKFVTKMYDLLLLKC 353
EN + + Q N V H + R + D
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAA 190
Query: 354 ARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
L D N + VL+ G +PL +AA + + Q ++ R
Sbjct: 191 VLLQNDPNPD-VLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 32.3 bits (72), Expect = 2.0
Identities = 43/193 (22%), Positives = 66/193 (34%), Gaps = 41/193 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF------------- 284
G T LHIA ++ +ELL+ GA + A P +
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL-TPLHVASFMGHLPIVKNLLQRGAS 429
Query: 285 -------GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHA--------LV 329
E PL +AA + YL +N KA + + T LH +V
Sbjct: 430 PNVSNVKVETPLHMAARAGHTEVAKYLLQN---KAKVNAKAKDDQTPLHCAARIGHTNMV 486
Query: 330 AIADNTRENTKFVTKMYDLLLLKCAR---------LFPDSNLEAVLNNDGLSPLMMAAKT 380
+ N T L AR L +A + G +PL +AAK
Sbjct: 487 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKY 546
Query: 381 GKIGIFQHIIRRE 393
GK+ + + ++ R+
Sbjct: 547 GKVRVAELLLERD 559
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 38.1 bits (87), Expect = 0.036
Identities = 55/219 (25%), Positives = 84/219 (38%), Gaps = 36/219 (16%)
Query: 195 LPKALLNLSNGR-----NDTIPVLLDIAERTGNMREFINSPFRDIYY-----RGQTALHI 244
L KAL +L NG N L +A + G+++ + ++I +G TALHI
Sbjct: 25 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 84
Query: 245 AIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYL 304
A V LV GA+V+AQ++ F PL +AA N +V +L
Sbjct: 85 AALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQENHLEVVKFL 130
Query: 305 TENPHKK----------ADMRRQDSRGNTVLHAL-VAIADNTRENTKFVTKMYDLLLLKC 353
EN + + Q N V H + R + D
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAA 190
Query: 354 ARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
L D N + VL+ G +PL +AA + + Q ++ R
Sbjct: 191 VLLQNDPNPD-VLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 32.3 bits (72), Expect = 2.0
Identities = 43/193 (22%), Positives = 66/193 (34%), Gaps = 41/193 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF------------- 284
G T LHIA ++ +ELL+ GA + A P +
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL-TPLHVASFMGHLPIVKNLLQRGAS 429
Query: 285 -------GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHA--------LV 329
E PL +AA + YL +N KA + + T LH +V
Sbjct: 430 PNVSNVKVETPLHMAARAGHTEVAKYLLQN---KAKVNAKAKDDQTPLHCAARIGHTNMV 486
Query: 330 AIADNTRENTKFVTKMYDLLLLKCAR---------LFPDSNLEAVLNNDGLSPLMMAAKT 380
+ N T L AR L +A + G +PL +AAK
Sbjct: 487 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKY 546
Query: 381 GKIGIFQHIIRRE 393
GK+ + + ++ R+
Sbjct: 547 GKVRVAELLLERD 559
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 38.1 bits (87), Expect = 0.036
Identities = 55/219 (25%), Positives = 84/219 (38%), Gaps = 36/219 (16%)
Query: 195 LPKALLNLSNGR-----NDTIPVLLDIAERTGNMREFINSPFRDIYY-----RGQTALHI 244
L KAL +L NG N L +A + G+++ + ++I +G TALHI
Sbjct: 25 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 84
Query: 245 AIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYL 304
A V LV GA+V+AQ++ F PL +AA N +V +L
Sbjct: 85 AALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQENHLEVVKFL 130
Query: 305 TENPHKK----------ADMRRQDSRGNTVLHAL-VAIADNTRENTKFVTKMYDLLLLKC 353
EN + + Q N V H + R + D
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAA 190
Query: 354 ARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
L D N + VL+ G +PL +AA + + Q ++ R
Sbjct: 191 VLLQNDPNPD-VLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 32.3 bits (72), Expect = 2.0
Identities = 43/193 (22%), Positives = 66/193 (34%), Gaps = 41/193 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF------------- 284
G T LHIA ++ +ELL+ GA + A P +
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL-TPLHVASFMGHLPIVKNLLQRGAS 429
Query: 285 -------GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHA--------LV 329
E PL +AA + YL +N KA + + T LH +V
Sbjct: 430 PNVSNVKVETPLHMAARAGHTEVAKYLLQN---KAKVNAKAKDDQTPLHCAARIGHTNMV 486
Query: 330 AIADNTRENTKFVTKMYDLLLLKCAR---------LFPDSNLEAVLNNDGLSPLMMAAKT 380
+ N T L AR L +A + G +PL +AAK
Sbjct: 487 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKY 546
Query: 381 GKIGIFQHIIRRE 393
GK+ + + ++ R+
Sbjct: 547 GKVRVAELLLERD 559
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 38.1 bits (87), Expect = 0.036
Identities = 55/219 (25%), Positives = 84/219 (38%), Gaps = 36/219 (16%)
Query: 195 LPKALLNLSNGR-----NDTIPVLLDIAERTGNMREFINSPFRDIYY-----RGQTALHI 244
L KAL +L NG N L +A + G+++ + ++I +G TALHI
Sbjct: 25 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 84
Query: 245 AIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYL 304
A V LV GA+V+AQ++ F PL +AA N +V +L
Sbjct: 85 AALAGQDEVVRELVNYGANVNAQSQKGF--------------TPLYMAAQENHLEVVKFL 130
Query: 305 TENPHKK----------ADMRRQDSRGNTVLHAL-VAIADNTRENTKFVTKMYDLLLLKC 353
EN + + Q N V H + R + D
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAA 190
Query: 354 ARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
L D N + VL+ G +PL +AA + + Q ++ R
Sbjct: 191 VLLQNDPNPD-VLSKTGFTPLHIAAHYENLNVAQLLLNR 228
Score = 32.3 bits (72), Expect = 2.0
Identities = 43/193 (22%), Positives = 66/193 (34%), Gaps = 41/193 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF------------- 284
G T LHIA ++ +ELL+ GA + A P +
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGL-TPLHVASFMGHLPIVKNLLQRGAS 429
Query: 285 -------GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHA--------LV 329
E PL +AA + YL +N KA + + T LH +V
Sbjct: 430 PNVSNVKVETPLHMAARAGHTEVAKYLLQN---KAKVNAKAKDDQTPLHCAARIGHTNMV 486
Query: 330 AIADNTRENTKFVTKMYDLLLLKCAR---------LFPDSNLEAVLNNDGLSPLMMAAKT 380
+ N T L AR L +A + G +PL +AAK
Sbjct: 487 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKY 546
Query: 381 GKIGIFQHIIRRE 393
GK+ + + ++ R+
Sbjct: 547 GKVRVAELLLERD 559
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 38.1 bits (87), Expect = 0.036
Identities = 44/179 (24%), Positives = 70/179 (39%), Gaps = 50/179 (27%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
+G TALHIA V++LV GA+V+AQ++ F PL +AA N
Sbjct: 106 KGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGF--------------TPLYMAAQEN 151
Query: 297 QPHIVNYLTENPHKK-----------------------ADMRRQDSRGNTVLHALVAIAD 333
+V +L +N + + + D++G L AL A
Sbjct: 152 HLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAA- 210
Query: 334 NTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
+++TK A L + N V + G +PL +AA G I + ++ R
Sbjct: 211 -RKDDTK-----------AAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNR 257
Score = 37.0 bits (84), Expect = 0.080
Identities = 41/161 (25%), Positives = 66/161 (40%), Gaps = 33/161 (20%)
Query: 237 RGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 296
RG+TALH+A V LV GA V A+A KD+ + PL ++A
Sbjct: 465 RGETALHMAARSGQAEVVRYLVQDGAQVEAKA-------KDD-------QTPLHISARLG 510
Query: 297 QPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARL 356
+ IV L + + A + G T LH + RE + V A L
Sbjct: 511 KADIVQQLLQ---QGASPNAATTSGYTPLHL------SAREGHEDV----------AAFL 551
Query: 357 FPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDE 397
++ G +PL +AAK GK+ + ++++ + +
Sbjct: 552 LDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPD 592
Score = 35.8 bits (81), Expect = 0.18
Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 33/155 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LHIA ++ +ELL+ GA + A G P+ +AA
Sbjct: 400 GFTPLHIACKKNRIKVMELLLKHGASIQAVTES--------------GLTPIHVAAFMGH 445
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLF 357
+IV+ L H A + RG T LH +A E +++ +
Sbjct: 446 VNIVSQLM---HHGASPNTTNVRGETALH--MAARSGQAEVVRYLVQ------------- 487
Query: 358 PDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
+ +EA +D +PL ++A+ GK I Q ++++
Sbjct: 488 DGAQVEAKAKDD-QTPLHISARLGKADIVQQLLQQ 521
Score = 33.9 bits (76), Expect = 0.67
Identities = 41/155 (26%), Positives = 60/155 (38%), Gaps = 33/155 (21%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LH+A + LL+ QGA HA A+ G PL +AA NQ
Sbjct: 598 GLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN--------------GYTPLHIAAKKNQ 643
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLF 357
I L E AD +G +H M LLL + A +
Sbjct: 644 MDIATTLLE---YGADANAVTRQGIASVHLAAQEGH---------VDMVSLLLGRNANV- 690
Query: 358 PDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 392
NL N GL+PL +AA+ ++ + + ++ +
Sbjct: 691 ---NLS---NKSGLTPLHLAAQEDRVNVAEVLVNQ 719
Score = 32.0 bits (71), Expect = 2.6
Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 17/89 (19%)
Query: 238 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 297
G T LH+A + + E+LV QGA V AQ + G PL +
Sbjct: 697 GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK--------------MGYTPLHVGCHYGN 742
Query: 298 PHIVNYLTENPHKKADMRRQDSRGNTVLH 326
IVN+L ++ A + + G T LH
Sbjct: 743 IKIVNFLLQH---SAKVNAKTKNGYTPLH 768
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,266,740
Number of Sequences: 37866
Number of extensions: 1760087
Number of successful extensions: 7462
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 126
Number of HSP's that attempted gapping in prelim test: 6940
Number of HSP's gapped (non-prelim): 556
length of query: 871
length of database: 18,247,518
effective HSP length: 111
effective length of query: 760
effective length of database: 14,044,392
effective search space: 10673737920
effective search space used: 10673737920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.