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Search of human proteins with 22547176
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
sapiens]
(746 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap... 1521 0.0
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap... 1466 0.0
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap... 1457 0.0
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap... 1261 0.0
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap... 1146 0.0
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap... 1146 0.0
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap... 1137 0.0
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] 437 e-122
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 428 e-119
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 237 3e-62
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 237 3e-62
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [... 221 2e-57
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ... 221 2e-57
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [... 221 2e-57
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 155 2e-37
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa... 124 4e-28
gi|4505531 oxysterol binding protein [Homo sapiens] 114 3e-25
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [... 109 8e-24
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H... 109 8e-24
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [... 99 1e-20
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [... 99 1e-20
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 97 4e-20
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [... 97 7e-20
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [... 90 9e-18
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [... 90 9e-18
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [... 90 9e-18
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] 86 1e-16
gi|54792084 pleckstrin homology domain containing, family A (pho... 84 4e-16
gi|14165452 alpha 3 type IV collagen binding protein isoform 2 [... 82 2e-15
gi|194294543 alpha 3 type IV collagen binding protein isoform 3 ... 82 2e-15
>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
sapiens]
Length = 746
Score = 1521 bits (3938), Expect = 0.0
Identities = 746/746 (100%), Positives = 746/746 (100%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS 120
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS 120
Query: 121 PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 180
PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE
Sbjct: 121 PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 180
Query: 181 TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC 240
TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC
Sbjct: 181 TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC 240
Query: 241 KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS 300
KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS
Sbjct: 241 KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS 300
Query: 301 SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA 360
SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA
Sbjct: 301 SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA 360
Query: 361 DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF 420
DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF
Sbjct: 361 DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF 420
Query: 421 FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN 480
FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN
Sbjct: 421 FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN 480
Query: 481 DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL 540
DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL
Sbjct: 481 DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL 540
Query: 541 GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI 600
GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI
Sbjct: 541 GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI 600
Query: 601 IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII 660
IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII
Sbjct: 601 IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII 660
Query: 661 KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE 720
KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE
Sbjct: 661 KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE 720
Query: 721 TRLFHEDGECWVYDEPLLKRLGAAKH 746
TRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 721 TRLFHEDGECWVYDEPLLKRLGAAKH 746
>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
sapiens]
Length = 723
Score = 1466 bits (3796), Expect = 0.0
Identities = 723/746 (96%), Positives = 723/746 (96%), Gaps = 23/746 (3%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS 120
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ-------------- 106
Query: 121 PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 180
GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE
Sbjct: 107 ---------GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 157
Query: 181 TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC 240
TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC
Sbjct: 158 TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC 217
Query: 241 KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS 300
KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS
Sbjct: 218 KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS 277
Query: 301 SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA 360
SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA
Sbjct: 278 SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA 337
Query: 361 DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF 420
DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF
Sbjct: 338 DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF 397
Query: 421 FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN 480
FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN
Sbjct: 398 FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN 457
Query: 481 DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL 540
DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL
Sbjct: 458 DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL 517
Query: 541 GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI 600
GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI
Sbjct: 518 GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI 577
Query: 601 IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII 660
IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII
Sbjct: 578 IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII 637
Query: 661 KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE 720
KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE
Sbjct: 638 KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE 697
Query: 721 TRLFHEDGECWVYDEPLLKRLGAAKH 746
TRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 698 TRLFHEDGECWVYDEPLLKRLGAAKH 723
>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
Length = 736
Score = 1457 bits (3772), Expect = 0.0
Identities = 723/759 (95%), Positives = 723/759 (95%), Gaps = 36/759 (4%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS 120
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ-------------- 106
Query: 121 PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 180
GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE
Sbjct: 107 ---------GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 157
Query: 181 TLKETTNSMVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMP 227
TLKETTNSMVESIKHCIVLLQIAK STINPVDAIYQPSPLEPVISTMP
Sbjct: 158 TLKETTNSMVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMP 217
Query: 228 SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN 287
SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN
Sbjct: 218 SQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVN 277
Query: 288 LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE 347
LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE
Sbjct: 278 LSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTE 337
Query: 348 SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI 407
SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI
Sbjct: 338 SLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFI 397
Query: 408 LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI 467
LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI
Sbjct: 398 LERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPI 457
Query: 468 LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI 527
LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI
Sbjct: 458 LGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKI 517
Query: 528 QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC 587
QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC
Sbjct: 518 QFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGEC 577
Query: 588 NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE 647
NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE
Sbjct: 578 NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE 637
Query: 648 NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA 707
NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA
Sbjct: 638 NTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRA 697
Query: 708 EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH 746
EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 698 EARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGAAKH 736
>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
sapiens]
Length = 626
Score = 1261 bits (3263), Expect = 0.0
Identities = 617/617 (100%), Positives = 617/617 (100%)
Query: 130 GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM 189
GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM
Sbjct: 10 GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM 69
Query: 190 VESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSL 249
VESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSL
Sbjct: 70 VESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSL 129
Query: 250 PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD 309
PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD
Sbjct: 130 PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD 189
Query: 310 EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR 369
EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR
Sbjct: 190 EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR 249
Query: 370 DDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVS 429
DDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVS
Sbjct: 250 DDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVS 309
Query: 430 ISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELV 489
ISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELV
Sbjct: 310 ISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELV 369
Query: 490 SEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNI 549
SEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNI
Sbjct: 370 SEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNI 429
Query: 550 GQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYG 609
GQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYG
Sbjct: 430 GQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYG 489
Query: 610 GKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLED 669
GKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLED
Sbjct: 490 GKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLED 549
Query: 670 QNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGE 729
QNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGE
Sbjct: 550 QNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGE 609
Query: 730 CWVYDEPLLKRLGAAKH 746
CWVYDEPLLKRLGAAKH
Sbjct: 610 CWVYDEPLLKRLGAAKH 626
>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 1146 bits (2964), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 189 MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS 248
MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS
Sbjct: 1 MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS 60
Query: 249 LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA 308
LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA
Sbjct: 61 LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA 120
Query: 309 DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD 368
DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD
Sbjct: 121 DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD 180
Query: 369 RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV 428
RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV
Sbjct: 181 RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV 240
Query: 429 SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL 488
SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL
Sbjct: 241 SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL 300
Query: 489 VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN 548
VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN
Sbjct: 301 VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN 360
Query: 549 IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY 608
IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY
Sbjct: 361 IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY 420
Query: 609 GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE 668
GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE
Sbjct: 421 GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE 480
Query: 669 DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 728
DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG
Sbjct: 481 DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 540
Query: 729 ECWVYDEPLLKRLGAAKH 746
ECWVYDEPLLKRLGAAKH
Sbjct: 541 ECWVYDEPLLKRLGAAKH 558
>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 1146 bits (2964), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 189 MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS 248
MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS
Sbjct: 1 MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS 60
Query: 249 LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA 308
LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA
Sbjct: 61 LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA 120
Query: 309 DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD 368
DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD
Sbjct: 121 DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD 180
Query: 369 RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV 428
RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV
Sbjct: 181 RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV 240
Query: 429 SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL 488
SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL
Sbjct: 241 SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL 300
Query: 489 VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN 548
VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN
Sbjct: 301 VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN 360
Query: 549 IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY 608
IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY
Sbjct: 361 IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY 420
Query: 609 GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE 668
GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE
Sbjct: 421 GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE 480
Query: 669 DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 728
DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG
Sbjct: 481 DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 540
Query: 729 ECWVYDEPLLKRLGAAKH 746
ECWVYDEPLLKRLGAAKH
Sbjct: 541 ECWVYDEPLLKRLGAAKH 558
>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
sapiens]
Length = 571
Score = 1137 bits (2940), Expect = 0.0
Identities = 558/571 (97%), Positives = 558/571 (97%), Gaps = 13/571 (2%)
Query: 189 MVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPE 235
MVESIKHCIVLLQIAK STINPVDAIYQPSPLEPVISTMPSQTVLPPE
Sbjct: 1 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 60
Query: 236 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 295
PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE
Sbjct: 61 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 120
Query: 296 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 355
FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN
Sbjct: 121 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 180
Query: 356 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 415
GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE
Sbjct: 181 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 240
Query: 416 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 475
MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH
Sbjct: 241 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 300
Query: 476 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 535
WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT
Sbjct: 301 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 360
Query: 536 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 595
KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG
Sbjct: 361 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 420
Query: 596 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 655
YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK
Sbjct: 421 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 480
Query: 656 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 715
KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK
Sbjct: 481 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 540
Query: 716 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 746
EIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 541 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 571
>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
Length = 747
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 358 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 417
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
Query: 418 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 477
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
Query: 478 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 521
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
Query: 522 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 581
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
Query: 582 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 641
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
Query: 642 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 701
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Query: 702 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 739
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
Score = 77.0 bits (188), Expect = 6e-14
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Query: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
G L K+TN++ GWQYR+FVL+ AGLL Y+ + ++ RG ++L GAVI DED
Sbjct: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKPRGTLQLAGAVISPSDEDSH 121
Query: 67 TFTI-TVDQKTFHFQARDADEREKWIHALEETILRHT 102
TFT+ + + +A DA ER+ W+ L+ HT
Sbjct: 122 TFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHT 158
>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
sapiens]
Length = 764
Score = 428 bits (1100), Expect = e-119
Identities = 210/420 (50%), Positives = 282/420 (67%), Gaps = 14/420 (3%)
Query: 329 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHL 388
++L +S+ +P+ + S L S+ + D+ D ++ E G +E+ +S+I+HL
Sbjct: 348 AILPNSAEDEQTSQPEPEPNSGSELV--LSEDEKSDNEDK--EETELGVMEDQRSIILHL 403
Query: 389 LSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYL 448
+SQ++LGMDLTKVVLPTFILE+RSLLEMYADF AHPDL ++I+ P++R++ V++YL
Sbjct: 404 ISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYL 463
Query: 449 SAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPV-----PWVSKNS-- 501
+AFH GRKG++AKKPYNPI+GE F C W +P D + S P P S
Sbjct: 464 TAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKS 523
Query: 502 --VTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDY 559
+ FVAEQVSHHPPIS FY EC K++ N H+WTKSKF+GMS+GV IG+G + L++
Sbjct: 524 YKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEH 583
Query: 560 DEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEI 619
E Y+ T P+ Y RSILT+PWVELGG+ +INC+KTGYSA +IFHTKPFYGGK HR+TAE+
Sbjct: 584 GEEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEV 643
Query: 620 FSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLW 679
C GEWNG + Y GE V +DT LP+ KK+R LE Q ESR+LW
Sbjct: 644 KHNPTNTIVCKAHGEWNGTLEFTYNNGETKV-IDTTTLPVYPKKIRPLEKQGPMESRNLW 702
Query: 680 KDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 739
++VT L++ DIDAATE K LEE+QR E R+R+ W+ + F ++G+ WVY PL K
Sbjct: 703 REVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWK 762
Score = 70.5 bits (171), Expect = 5e-12
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Query: 5 MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
+EG LSK+TN+++GWQ R+FVLD+ AG+L Y+ + ++ RG + L GA++ + DE
Sbjct: 77 LEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVN-EQSKHQKPRGVLSLSGAIVSLSDEA 135
Query: 65 DSTFTI-TVDQKTFHFQARDADEREKWIHALEETILRH 101
+ + + + F +A DA E++ W+ L H
Sbjct: 136 PHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYH 173
>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
[Homo sapiens]
Length = 847
Score = 237 bits (604), Expect = 3e-62
Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)
Query: 298 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 357
YS D+ + D+ H S ++ S + T +S P+ E L +
Sbjct: 285 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 340
Query: 358 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 417
S +L ++ + + + EE+KS+I LL QVR GMDL+KVVLPTFILE RS L+
Sbjct: 341 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 397
Query: 418 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 477
+D++ H D + +++P R+ +VVKWYLS F+ KG KKPYNPILGE F+C W
Sbjct: 398 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 455
Query: 478 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 536
P NS TF +AEQVSHHPPISAFY + I K
Sbjct: 456 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 497
Query: 537 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 595
SKF G S+ G+ ++ L+ E Y++T P + + IL +ELGG NI C KTG
Sbjct: 498 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 557
Query: 596 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 651
YSA + F KPF G ++I+ ++ K+ ++EG W+ V T + VF
Sbjct: 558 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 615
Query: 652 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 708
D K+ +I+ V K E+Q ++ES LW+ VT + +D AT+ K+ LEE QR
Sbjct: 616 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 674
Query: 709 ARERKEKEIQWETRLFHED 727
AR+RK K +W +LF D
Sbjct: 675 ARDRKTKNEEWSCKLFELD 693
>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
Length = 889
Score = 237 bits (604), Expect = 3e-62
Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)
Query: 298 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 357
YS D+ + D+ H S ++ S + T +S P+ E L +
Sbjct: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
Query: 358 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 417
S +L ++ + + + EE+KS+I LL QVR GMDL+KVVLPTFILE RS L+
Sbjct: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
Query: 418 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 477
+D++ H D + +++P R+ +VVKWYLS F+ KG KKPYNPILGE F+C W
Sbjct: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
Query: 478 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 536
P NS TF +AEQVSHHPPISAFY + I K
Sbjct: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
Query: 537 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 595
SKF G S+ G+ ++ L+ E Y++T P + + IL +ELGG NI C KTG
Sbjct: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
Query: 596 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 651
YSA + F KPF G ++I+ ++ K+ ++EG W+ V T + VF
Sbjct: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
Query: 652 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 708
D K+ +I+ V K E+Q ++ES LW+ VT + +D AT+ K+ LEE QR
Sbjct: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
Query: 709 ARERKEKEIQWETRLFHED 727
AR+RK K +W +LF D
Sbjct: 717 ARDRKTKNEEWSCKLFELD 735
>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
[Homo sapiens]
Length = 879
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 290 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 336
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 261 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 320
Query: 337 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 392
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 321 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 378
Query: 393 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 452
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 379 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 438
Query: 453 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 512
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 439 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 479
Query: 513 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 572
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 480 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 539
Query: 573 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 629
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 540 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 597
Query: 630 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 685
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 598 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 657
Query: 686 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 727
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 658 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 699
>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 290 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 336
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 193 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 252
Query: 337 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 392
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 253 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 310
Query: 393 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 452
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 311 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 370
Query: 453 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 512
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 371 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 411
Query: 513 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 572
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
Query: 573 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 629
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 529
Query: 630 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 685
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 530 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 589
Query: 686 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 727
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 290 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 336
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 193 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 252
Query: 337 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 392
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 253 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 310
Query: 393 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 452
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 311 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 370
Query: 453 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 512
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 371 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 411
Query: 513 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 572
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
Query: 573 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 629
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 529
Query: 630 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 685
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 530 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 589
Query: 686 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 727
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
sapiens]
Length = 950
Score = 155 bits (391), Expect = 2e-37
Identities = 193/807 (23%), Positives = 301/807 (37%), Gaps = 190/807 (23%)
Query: 6 EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSK-DKMMRGSRRGCVRLRGAVIGIDDED 64
EGPL K + GW+ W VL++ G+LS+Y + D + R+GC L AV + D
Sbjct: 239 EGPLWKSSRFF-GWRLFWVVLEH--GVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTD 295
Query: 65 DSTFTITVDQKTFH-FQARD---ADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS 120
F I T H F+ RE W+ A+EE T
Sbjct: 296 SCLFFIKCFDDTIHGFRVPKNSLQQSREDWLEAIEEHSAYSTHYCS-------------- 341
Query: 121 PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 180
QD +LT+ + + LK +K Q+C++ R+
Sbjct: 342 -------------------QD---QLTDEEEEDTVSAADLKKSLEKAQSCQQRLDRE--- 376
Query: 181 TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC 240
++ ++ IK C + ++ S + V+ + + S V T E V+
Sbjct: 377 -----ISNFLKMIKECDMAKEMLPSFLQKVEVVSEASRETCVALTDCLNLFTKQEGVRNF 431
Query: 241 KSEQRPSSLPV-GPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYS 299
K EQ + L TL S G SPP+S L
Sbjct: 432 KLEQEQEKNKILSEALETLATEHHELEQSLVKG-SPPASIL------------------- 471
Query: 300 SSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSD 359
SEDEFYDA S S +R + + + + G L G+
Sbjct: 472 -SEDEFYDA----LSDSESERSLSRLEAVTARSFEEEGEHL---------------GSRK 511
Query: 360 ADLFDSHDDRDDDAEAGSVEEHKSVI---------MHLLSQVR--LGMDLTKVVLPTFIL 408
+ + D DA + +++H++ + + S +R +GM+L+K+ +P
Sbjct: 512 HRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFN 571
Query: 409 ERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPIL 468
E S L+ ++ H L S DP +RM V + +SA + KP+NP+L
Sbjct: 572 EPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--VASQWERTGKPFNPLL 629
Query: 469 GEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQ 528
GE + ELV + ++EQVSHHPPISAF+AE N
Sbjct: 630 GETY--------------ELVRD-------DLGFRLISEQVSHHPPISAFHAEGLNNDFI 668
Query: 529 FNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGEC 587
F+ I+ K KF G S+ G + L+++E Y T P +I+ W+E G
Sbjct: 669 FHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNV 728
Query: 588 NINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGE 647
I KTG + F +G + H++ I KK C++ G+W +Y+
Sbjct: 729 EIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALYGKWTECLYSVDPATF 787
Query: 648 NTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRSLWK------------ 680
+ + KK KK +++ E + S LW+
Sbjct: 788 DAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMY 847
Query: 681 -----------------------DVTFNLKIR-----DIDAATEAKHRLEERQRAEARER 712
D IR +ID A+E K RLEE+QRA + R
Sbjct: 848 NFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNR 907
Query: 713 KEKEIQWETRLFHE------DGECWVY 733
+ E W+TR FH+ + W+Y
Sbjct: 908 SKSEEDWKTRWFHQGPNPYNGAQDWIY 934
>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
sapiens]
Length = 437
Score = 124 bits (310), Expect = 4e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 394 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 453
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
Query: 454 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 513
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
Query: 514 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 573
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
Query: 574 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 632
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
Query: 633 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 677
G+W +Y+ + + KK KK +++ E + S
Sbjct: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
Query: 678 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 697
LW+ D IR +ID A+E
Sbjct: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
Query: 698 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 733
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 114 bits (285), Expect = 3e-25
Identities = 177/767 (23%), Positives = 301/767 (39%), Gaps = 135/767 (17%)
Query: 3 SIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDD 62
S EG L KWTN +KG+Q RWFVL + GLLSYY SK + MR + RG + L A I
Sbjct: 89 SAREGWLFKWTNYIKGYQRRWFVL--SNGLLSYYRSKAE-MRHTCRGTINL--ATANITV 143
Query: 63 EDDSTFTIT-VDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISP 121
ED F I+ +T+H +A ER++W+ ALE + L S +S +
Sbjct: 144 EDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTD 203
Query: 122 VLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQ---ILIEQLKLFDDKLQNCKEDEQRKK 178
E + S V + + + + LQ +E LKL + + K+ +R
Sbjct: 204 KTELQNTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLKLPAESNEKIKQVNERAT 263
Query: 179 IETLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPV- 237
+ + T+N+M+ + + ++L Q +Q S + Q + E +
Sbjct: 264 L--FRITSNAMINACRDFLMLAQTHSKK-------WQKS-----LQYERDQRIRLEETLE 309
Query: 238 QLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFS 297
QL K G + TP + GSG S + S
Sbjct: 310 QLAKQHNHLERAFRGATVLPAN-----TPGNVGSGKDQCCSG-------------KGDMS 351
Query: 298 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 357
E+EF+DA E + L H +G S++S +
Sbjct: 352 DEDDENEFFDAPEIITMPEN-------------LGHKRTG-------------SNISGAS 385
Query: 358 SDADLFDSHDDRDDDAEAGS-----VEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRS 412
SD L + + + ++ + + + S+ + + + +G +L+K+ +P E S
Sbjct: 386 SDISLDEQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLS 445
Query: 413 LLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIF 472
+L+ + + +L + ++ +++ V + +S++ KP+NP+LGE F
Sbjct: 446 MLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSY--STTVFRTSKPFNPLLGETF 503
Query: 473 QCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAH 532
+ + + +N + EQVSHHPP +A +AE N
Sbjct: 504 E--------------------LDRLEENGYRSLCEQVSHHPPAAAHHAESKN-GWTLRQE 542
Query: 533 IWTKSKFLGMSIGVHNIGQGCVSCLDY--DEHYILTFPNGYGRSILTVP-WVELGGECNI 589
I SKF G + + + G + C+ + HY +I+ W++ GE +I
Sbjct: 543 IKITSKFRGKYLSIMPL--GTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDI 600
Query: 590 NCSKTGYSANIIFHTKPFYG-GKKHRITAEIFSPNDKKSFCSIEGEWNGVM---YAKYAT 645
KTG N+ F ++ ++T E+ P+ K F ++ G W+ M +
Sbjct: 601 VNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHF-ALLGTWDEKMECFKVQPVI 659
Query: 646 GEN-------TVFVDTKKLPIIKKKVRKLEDQNEYESRSL------WKDVTFNLKIR--- 689
GEN + ++ + K+ +N Y L W+ T R
Sbjct: 660 GENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWESGTAPTDSRLRP 719
Query: 690 --------DIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 728
D A K RLEE+QR +R+++E E T EDG
Sbjct: 720 DQRLMENGRWDEANAEKQRLEEKQRL-SRKKREAEAMKAT----EDG 761
>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
[Homo sapiens]
Length = 480
Score = 109 bits (273), Expect = 8e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 394 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 453
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
Query: 454 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 513
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
Query: 514 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 573
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
Query: 574 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 632
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
Query: 633 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 668
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
Query: 669 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 696
+ S ++ +F + + +++ E
Sbjct: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
Query: 697 --AKHRLEERQRAEARERKEKEIQWETRLFH 725
K RLEE+QR RER ++E +W+TR F+
Sbjct: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
sapiens]
Length = 468
Score = 109 bits (273), Expect = 8e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 394 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 453
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 72 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 129
Query: 454 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 513
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 130 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 168
Query: 514 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 573
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 169 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 228
Query: 574 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 632
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 229 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 287
Query: 633 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 668
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 288 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 347
Query: 669 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 696
+ S ++ +F + + +++ E
Sbjct: 348 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 407
Query: 697 --AKHRLEERQRAEARERKEKEIQWETRLFH 725
K RLEE+QR RER ++E +W+TR F+
Sbjct: 408 SQEKERLEEKQREARRERAKEEAEWQTRWFY 438
>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
[Homo sapiens]
Length = 938
Score = 99.4 bits (246), Expect = 1e-20
Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)
Query: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356
S S S EF+DA E S SS + ++S S ++ S S ++++ + NG
Sbjct: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
Query: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416
F + R A + + ++L +G DL+KV +P + E + L+
Sbjct: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
Query: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474
+ + +L S+ DP +RMV V + +S + + R GS KP+NP+LGE ++C
Sbjct: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
Query: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534
+ E F +EQVSHHPPISA C +K F I
Sbjct: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
Query: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 593
K+KF G S+ + +G V Y ++Y+ +IL+ W+E GE I +K
Sbjct: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
Query: 594 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 651
+ + K Y + + K+ + G+W+ +Y A ++
Sbjct: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
Query: 652 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 693
++ +L P++K + + + + R L + +++A
Sbjct: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
Query: 694 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 735
A K R+EE QR+ R +E ++ + F + E WV ++
Sbjct: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
Score = 34.7 bits (78), Expect = 0.33
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVLD G+L Y + + +G G + + +V+ I + +
Sbjct: 77 KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 131
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + D + W+ L
Sbjct: 132 DTEEHIYHLKVKSQDWFDAWVSKL 155
>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
[Homo sapiens]
Length = 934
Score = 99.4 bits (246), Expect = 1e-20
Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)
Query: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356
S S S EF+DA E S SS + ++S S ++ S S ++++ + NG
Sbjct: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
Query: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416
F + R A + + ++L +G DL+KV +P + E + L+
Sbjct: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
Query: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474
+ + +L S+ DP +RMV V + +S + + R GS KP+NP+LGE ++C
Sbjct: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
Query: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534
+ E F +EQVSHHPPISA C +K F I
Sbjct: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
Query: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 593
K+KF G S+ + +G V Y ++Y+ +IL+ W+E GE I +K
Sbjct: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
Query: 594 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 651
+ + K Y + + K+ + G+W+ +Y A ++
Sbjct: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
Query: 652 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 693
++ +L P++K + + + + R L + +++A
Sbjct: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
Query: 694 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 735
A K R+EE QR+ R +E ++ + F + E WV ++
Sbjct: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
Score = 34.7 bits (78), Expect = 0.33
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVLD G+L Y + + +G G + + +V+ I + +
Sbjct: 98 KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 152
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + D + W+ L
Sbjct: 153 DTEEHIYHLKVKSQDWFDAWVSKL 176
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 97.4 bits (241), Expect = 4e-20
Identities = 177/778 (22%), Positives = 286/778 (36%), Gaps = 175/778 (22%)
Query: 6 EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDD 65
EG L KWTN +KG+Q RWFVL GLLSYY ++ +M + RG + L A ID ED
Sbjct: 186 EGWLLKWTNYLKGYQRRWFVL--GNGLLSYYRNQGEMAH-TCRGTINLSTA--HIDTEDS 240
Query: 66 STFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISPVLEF 125
+T +++H +A +R++WI ALE L +++ T +
Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITALE---LAKAKAVRVMNTHSD------------ 285
Query: 126 SKIIGLDSGFVPSVQDFDKKLTEAD-AYLQILIEQLKLFDDKLQNCKE------------ 172
DSG D D+ T AD + L ++ L L D L C +
Sbjct: 286 ------DSG------DDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRS 333
Query: 173 ----------DEQRKKIETLKE-------TTNSMVESIKHCIVLLQIAKSTINPVDAIYQ 215
E +K++ + E T+N+M+ + C L++A+
Sbjct: 334 LTELDGLKIPSESGEKLKVVNERATLFRITSNAMINA---CRDFLELAE----------- 379
Query: 216 PSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSP 275
I + Q L E Q E+ L H P + S
Sbjct: 380 -------IHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFI 432
Query: 276 PSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSS 335
S LT E S + E++DA E DS+ +V+T +
Sbjct: 433 EGSLLTPKG----------EDSEEDEDTEYFDAME------------DSTSFITVITEAK 470
Query: 336 SGNSLKRPDT-TESLN-SSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVR 393
+ T T S++ SS N A L + + + S+ + + +
Sbjct: 471 EDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNC 530
Query: 394 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 453
+G +L+++ +P E S+L+ + + L ++M V + +S++
Sbjct: 531 IGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSY-- 588
Query: 454 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 513
KP+NP+LGE F+ D ++ L S + EQVSHHP
Sbjct: 589 STTVHRIAKPFNPMLGETFEL------DRLDDMGLRS--------------LCEQVSHHP 628
Query: 514 PISAFYAECFNKKIQFNAHIWT-------KSKFLGMSIGVHNIGQGCVSCLDYDEHYILT 566
P +A Y F+ H W+ SKF G I + +G + HY+
Sbjct: 629 PSAAHYV--------FSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWR 680
Query: 567 FPNGYGRSILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDK 625
+I+ W++ G+ I KT + F ++ + R + S +
Sbjct: 681 KSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQG 740
Query: 626 KSFCSIEGEW------NGVMYAKYAT----GENTVFVDTKKLPIIKKKVRKLEDQ----- 670
K+ + G W + VM++ ++ G+ T ++ KK E+
Sbjct: 741 KAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYY 800
Query: 671 --------NEYE------SRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKE 714
NE+E L D K R +A TE K RLEE+QR R R E
Sbjct: 801 FSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857
>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
[Homo sapiens]
Length = 820
Score = 96.7 bits (239), Expect = 7e-20
Identities = 180/815 (22%), Positives = 306/815 (37%), Gaps = 144/815 (17%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISPVLEFSKIIG 130
++ +H + + + ++W+ L H + Q +A F ++ S I
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQ--NEIAMFPHE-VNHFFSGSTITD 170
Query: 131 LDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQ---NCKEDEQRKKIETLKETTN 187
SG S+ + I + LF +C + + E
Sbjct: 171 SSSGVFDSISSRKRS----------SISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDME 220
Query: 188 SMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLP-PEPVQLCKSEQRP 246
+ + HC L + +D +++ + P I+ + Q P PV+L S
Sbjct: 221 KCSKDLAHCHAYLVEMSQLLQSMDVLHR-TYSAPAINAI--QVPKPFSGPVRLHSSNPNL 277
Query: 247 SSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFY 306
S+L G + T S S L +H + F+ S+E E
Sbjct: 278 STLDFGE------EKNYSDGSETSSEFSKMQEDLCHIAH-KVYFTLRSAFNIMSAEREKL 330
Query: 307 DADEFHQSGSSP-------KRLIDSSGSAS---VLTHSSSGNSLKRPDTTESLN------ 350
+ SSP K + S S L H S S R T+SL+
Sbjct: 331 KQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNES--RLSITDSLSEFFDAQ 388
Query: 351 ------SSLSNGTSDADLF--DSHDDRDDDAEAGSVEEHKSVIMHLLSQVR--------- 393
SS N SD D + D D+ D + ++ + + +L R
Sbjct: 389 EVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTC 448
Query: 394 --------------------LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQ 433
+G DL+KV +P + E + L+ + + +L +
Sbjct: 449 LPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQI 508
Query: 434 KDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSE 491
P +RMV V + +SA+ + R GS KP+NP+LGE ++C + E
Sbjct: 509 PSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC--------------IRE 551
Query: 492 GPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQ 551
F +EQVSHHPPISA +AE ++ F + K+KF G S+ + IG
Sbjct: 552 -------DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGT 602
Query: 552 GCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYG 609
V+ + +H+ +IL+ W+E GE I N + F ++
Sbjct: 603 THVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWS 662
Query: 610 GKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE- 668
H I +F K+ + G+W+ +Y + V+ + P+ K +
Sbjct: 663 TNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW---RANPMPKGYEQYYSF 718
Query: 669 -----DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEAKHRLEERQRAEARERKE 714
+ NE + S+SL D F L+ +++ A K R+E+ QR R +E
Sbjct: 719 TQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEE 778
Query: 715 KEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 745
++ + R F + D + WV + L K LG +K
Sbjct: 779 NHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 813
>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
[Homo sapiens]
Length = 851
Score = 89.7 bits (221), Expect = 9e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
Query: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
Query: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
Query: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
Query: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 592
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
Query: 593 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 652
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
Query: 653 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 697
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
Query: 698 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 745
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
Score = 38.5 bits (88), Expect = 0.023
Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + + ++W+ L
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKL 141
>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
[Homo sapiens]
Length = 856
Score = 89.7 bits (221), Expect = 9e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 412 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 467
Query: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 468 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 527
Query: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 528 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 584
Query: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 585 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 621
Query: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 592
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 622 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 681
Query: 593 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 652
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 682 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 739
Query: 653 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 697
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 740 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 797
Query: 698 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 745
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 798 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 849
Score = 38.5 bits (88), Expect = 0.023
Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + + ++W+ L
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKL 141
>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
[Homo sapiens]
Length = 887
Score = 89.7 bits (221), Expect = 9e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
Query: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
Query: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
Query: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
Query: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 592
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
Query: 593 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 652
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
Query: 653 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 697
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
Query: 698 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 745
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
Score = 38.5 bits (88), Expect = 0.023
Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + + ++W+ L
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKL 141
>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
Length = 842
Score = 85.9 bits (211), Expect = 1e-16
Identities = 87/347 (25%), Positives = 145/347 (41%), Gaps = 43/347 (12%)
Query: 394 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 453
+G DL+KV +P + E + L+ + + L S DP +RMV + + +SA+ +
Sbjct: 487 IGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSS 546
Query: 454 G--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSH 511
R G KP+NP+LGE ++C E P F++EQVSH
Sbjct: 547 TYHRAGC---KPFNPVLGETYEC----------------ERP-----DRGFRFISEQVSH 582
Query: 512 HPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGY 571
HPPISA +AE ++ F + K+KF G S+ + +G VS + +H+
Sbjct: 583 HPPISACHAE--SENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSC 640
Query: 572 GRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFC 629
++L+ W+E GE I N + I F ++ H + + S +
Sbjct: 641 IHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLS-RSGRVLH 699
Query: 630 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKK------VRKLEDQNEYESRSLWKDVT 683
+ G+W+ +Y G ++ P ++ +L + RSL T
Sbjct: 700 RLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDT 759
Query: 684 ------FNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLF 724
L+ +I AA K R+E+ QR + +E I + R F
Sbjct: 760 RLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFF 806
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVL+ G+L Y T++ + +G G + +R +V+ I ++ +
Sbjct: 59 KWP--LKGWHKRYFVLE--DGILHYATTRQDITKGKLHGSIDVRLSVMSI-NKKAQRIDL 113
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQL 105
+ +H + + D + W+ L L H L +
Sbjct: 114 DTEDNIYHLKIKSQDLFQSWVAQLRAHRLAHRLDM 148
>gi|54792084 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 3 [Homo
sapiens]
Length = 300
Score = 84.3 bits (207), Expect = 4e-16
Identities = 84/326 (25%), Positives = 142/326 (43%), Gaps = 60/326 (18%)
Query: 5 MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
MEG L KWTN + GWQ RWFVLD G+LSYY S+D + +GS +G +++ I + D
Sbjct: 1 MEGVLYKWTNYLTGWQPRWFVLD--NGILSYYDSQDDVCKGS-KGSIKMAVCEIKVHSAD 57
Query: 65 DSTFTITV-DQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISPVL 123
++ + + ++ F+ +A +A ER++W+ AL ++ A +
Sbjct: 58 NTRMELIIPGEQHFYMKAVNAAERQRWLVAL-------------GSSKACLTDTRTKKEK 104
Query: 124 EFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLF------DDKLQNCKEDEQRK 177
E S+ + + K++E Y +L++Q+ D+ + + +
Sbjct: 105 EISE----------TSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNE 154
Query: 178 KIETLKETTNSMVESIKHCIVLLQIAKSTINP-VDAIYQPSPLEPVISTMPSQ----TVL 232
L T N+ + +++ C+ +IA + P + ++ P PL +S P Q +V
Sbjct: 155 ASSLLSATCNTFITTLEECV---KIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVS 211
Query: 233 PPEPVQLCKSEQRPSSL--PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHV---- 286
P C SE+ S+ PV L L + T + T S P P H
Sbjct: 212 HPGS---CSSERSSHSIKEPVS-TLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNT 267
Query: 287 ---NLSPNTVPEFS------YSSSED 303
+L+ T+PE S S SED
Sbjct: 268 LNGDLASATIPEESRLMAKKQSESED 293
>gi|14165452 alpha 3 type IV collagen binding protein isoform 2
[Homo sapiens]
Length = 598
Score = 81.6 bits (200), Expect = 2e-15
Identities = 61/185 (32%), Positives = 86/185 (46%), Gaps = 25/185 (13%)
Query: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
G LSKWTN + GWQ RW VL NA LSYY S+D+ G R G + L AVI D D+
Sbjct: 28 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 84
Query: 67 TFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISPVLEFS 126
F I+V+ ++ +A+D D R++WI A+E Q T + S +
Sbjct: 85 RFDISVNDSVWYLRAQDPDHRQQWIDAIE----------QHKTESGYGSESSLRRHGSMV 134
Query: 127 KIIGLDSGF-VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDE 174
++ SG+ S F K KL E + + IL Q+ C K++
Sbjct: 135 SLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDEL 194
Query: 175 QRKKI 179
QR K+
Sbjct: 195 QRDKV 199
>gi|194294543 alpha 3 type IV collagen binding protein isoform 3
[Homo sapiens]
Length = 752
Score = 81.6 bits (200), Expect = 2e-15
Identities = 61/185 (32%), Positives = 86/185 (46%), Gaps = 25/185 (13%)
Query: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
G LSKWTN + GWQ RW VL NA LSYY S+D+ G R G + L AVI D D+
Sbjct: 156 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 212
Query: 67 TFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISPVLEFS 126
F I+V+ ++ +A+D D R++WI A+E Q T + S +
Sbjct: 213 RFDISVNDSVWYLRAQDPDHRQQWIDAIE----------QHKTESGYGSESSLRRHGSMV 262
Query: 127 KIIGLDSGF-VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDE 174
++ SG+ S F K KL E + + IL Q+ C K++
Sbjct: 263 SLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDEL 322
Query: 175 QRKKI 179
QR K+
Sbjct: 323 QRDKV 327
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,660,360
Number of Sequences: 37866
Number of extensions: 1454201
Number of successful extensions: 8373
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 7295
Number of HSP's gapped (non-prelim): 1092
length of query: 746
length of database: 18,247,518
effective HSP length: 110
effective length of query: 636
effective length of database: 14,082,258
effective search space: 8956316088
effective search space used: 8956316088
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.