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Search of human proteins with 22547173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
sapiens]
(723 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap... 1479 0.0
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap... 1470 0.0
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap... 1466 0.0
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap... 1261 0.0
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap... 1146 0.0
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap... 1146 0.0
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap... 1137 0.0
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] 437 e-122
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 428 e-119
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 237 3e-62
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 237 3e-62
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [... 221 2e-57
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ... 221 2e-57
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [... 221 2e-57
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 164 3e-40
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa... 124 4e-28
gi|4505531 oxysterol binding protein [Homo sapiens] 115 2e-25
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [... 109 8e-24
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H... 109 8e-24
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 104 3e-22
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [... 99 1e-20
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [... 99 1e-20
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [... 99 1e-20
gi|54792084 pleckstrin homology domain containing, family A (pho... 92 2e-18
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [... 90 8e-18
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [... 90 8e-18
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [... 90 8e-18
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] 86 1e-16
gi|14249174 pleckstrin homology domain containing, family A (pho... 84 5e-16
gi|14165452 alpha 3 type IV collagen binding protein isoform 2 [... 83 1e-15
>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
sapiens]
Length = 723
Score = 1479 bits (3830), Expect = 0.0
Identities = 723/723 (100%), Positives = 723/723 (100%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA
Sbjct: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
Query: 181 KSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQT 240
KSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQT
Sbjct: 181 KSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQT 240
Query: 241 PTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLID 300
PTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLID
Sbjct: 241 PTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLID 300
Query: 301 SSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKS 360
SSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKS
Sbjct: 301 SSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKS 360
Query: 361 VIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQV 420
VIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQV
Sbjct: 361 VIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQV 420
Query: 421 VKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVT 480
VKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVT
Sbjct: 421 VKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVT 480
Query: 481 FVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHY 540
FVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHY
Sbjct: 481 FVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHY 540
Query: 541 ILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPN 600
ILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPN
Sbjct: 541 ILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPN 600
Query: 601 DKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVT 660
DKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVT
Sbjct: 601 DKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVT 660
Query: 661 FNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGA 720
FNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGA
Sbjct: 661 FNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLKRLGA 720
Query: 721 AKH 723
AKH
Sbjct: 721 AKH 723
>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
Length = 736
Score = 1470 bits (3806), Expect = 0.0
Identities = 723/736 (98%), Positives = 723/736 (98%), Gaps = 13/736 (1%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA
Sbjct: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
Query: 181 K-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 227
K STINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP
Sbjct: 181 KDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLP 240
Query: 228 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 287
VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE
Sbjct: 241 VGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADE 300
Query: 288 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 347
FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD
Sbjct: 301 FHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRD 360
Query: 348 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 407
DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI
Sbjct: 361 DDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSI 420
Query: 408 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 467
SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS
Sbjct: 421 SDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVS 480
Query: 468 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 527
EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG
Sbjct: 481 EGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIG 540
Query: 528 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 587
QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG
Sbjct: 541 QGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGG 600
Query: 588 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 647
KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ
Sbjct: 601 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 660
Query: 648 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 707
NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC
Sbjct: 661 NEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGEC 720
Query: 708 WVYDEPLLKRLGAAKH 723
WVYDEPLLKRLGAAKH
Sbjct: 721 WVYDEPLLKRLGAAKH 736
>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
sapiens]
Length = 746
Score = 1466 bits (3796), Expect = 0.0
Identities = 723/746 (96%), Positives = 723/746 (96%), Gaps = 23/746 (3%)
Query: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
Sbjct: 1 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI 60
Query: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ-------------- 106
DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQ
Sbjct: 61 DDEDDSTFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGIS 120
Query: 107 ---------GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 157
GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE
Sbjct: 121 PVLEFSKIIGLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIE 180
Query: 158 TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC 217
TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC
Sbjct: 181 TLKETTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLC 240
Query: 218 KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS 277
KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS
Sbjct: 241 KSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSS 300
Query: 278 SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA 337
SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA
Sbjct: 301 SEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDA 360
Query: 338 DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF 397
DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF
Sbjct: 361 DLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADF 420
Query: 398 FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN 457
FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN
Sbjct: 421 FAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPN 480
Query: 458 DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL 517
DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL
Sbjct: 481 DTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFL 540
Query: 518 GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI 577
GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI
Sbjct: 541 GMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANI 600
Query: 578 IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII 637
IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII
Sbjct: 601 IFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPII 660
Query: 638 KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE 697
KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE
Sbjct: 661 KKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWE 720
Query: 698 TRLFHEDGECWVYDEPLLKRLGAAKH 723
TRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 721 TRLFHEDGECWVYDEPLLKRLGAAKH 746
>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
sapiens]
Length = 626
Score = 1261 bits (3263), Expect = 0.0
Identities = 617/617 (100%), Positives = 617/617 (100%)
Query: 107 GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM 166
GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM
Sbjct: 10 GLDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM 69
Query: 167 VESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSL 226
VESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSL
Sbjct: 70 VESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSL 129
Query: 227 PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD 286
PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD
Sbjct: 130 PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD 189
Query: 287 EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR 346
EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR
Sbjct: 190 EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR 249
Query: 347 DDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVS 406
DDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVS
Sbjct: 250 DDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVS 309
Query: 407 ISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELV 466
ISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELV
Sbjct: 310 ISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELV 369
Query: 467 SEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNI 526
SEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNI
Sbjct: 370 SEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNI 429
Query: 527 GQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYG 586
GQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYG
Sbjct: 430 GQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYG 489
Query: 587 GKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLED 646
GKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLED
Sbjct: 490 GKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLED 549
Query: 647 QNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGE 706
QNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGE
Sbjct: 550 QNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGE 609
Query: 707 CWVYDEPLLKRLGAAKH 723
CWVYDEPLLKRLGAAKH
Sbjct: 610 CWVYDEPLLKRLGAAKH 626
>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 1146 bits (2964), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 166 MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS 225
MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS
Sbjct: 1 MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS 60
Query: 226 LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA 285
LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA
Sbjct: 61 LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA 120
Query: 286 DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD 345
DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD
Sbjct: 121 DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD 180
Query: 346 RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV 405
RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV
Sbjct: 181 RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV 240
Query: 406 SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL 465
SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL
Sbjct: 241 SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL 300
Query: 466 VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN 525
VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN
Sbjct: 301 VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN 360
Query: 526 IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY 585
IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY
Sbjct: 361 IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY 420
Query: 586 GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE 645
GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE
Sbjct: 421 GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE 480
Query: 646 DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 705
DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG
Sbjct: 481 DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 540
Query: 706 ECWVYDEPLLKRLGAAKH 723
ECWVYDEPLLKRLGAAKH
Sbjct: 541 ECWVYDEPLLKRLGAAKH 558
>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 1146 bits (2964), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 166 MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS 225
MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS
Sbjct: 1 MVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSS 60
Query: 226 LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA 285
LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA
Sbjct: 61 LPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDA 120
Query: 286 DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD 345
DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD
Sbjct: 121 DEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDD 180
Query: 346 RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV 405
RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV
Sbjct: 181 RDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFV 240
Query: 406 SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL 465
SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL
Sbjct: 241 SISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTEL 300
Query: 466 VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN 525
VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN
Sbjct: 301 VSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHN 360
Query: 526 IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY 585
IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY
Sbjct: 361 IGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFY 420
Query: 586 GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE 645
GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE
Sbjct: 421 GGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE 480
Query: 646 DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 705
DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG
Sbjct: 481 DQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 540
Query: 706 ECWVYDEPLLKRLGAAKH 723
ECWVYDEPLLKRLGAAKH
Sbjct: 541 ECWVYDEPLLKRLGAAKH 558
>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
sapiens]
Length = 571
Score = 1137 bits (2940), Expect = 0.0
Identities = 558/571 (97%), Positives = 558/571 (97%), Gaps = 13/571 (2%)
Query: 166 MVESIKHCIVLLQIAK-------------STINPVDAIYQPSPLEPVISTMPSQTVLPPE 212
MVESIKHCIVLLQIAK STINPVDAIYQPSPLEPVISTMPSQTVLPPE
Sbjct: 1 MVESIKHCIVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPE 60
Query: 213 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 272
PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE
Sbjct: 61 PVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPE 120
Query: 273 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 332
FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN
Sbjct: 121 FSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSN 180
Query: 333 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 392
GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE
Sbjct: 181 GTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLE 240
Query: 393 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 452
MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH
Sbjct: 241 MYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCH 300
Query: 453 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 512
WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT
Sbjct: 301 WTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT 360
Query: 513 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 572
KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG
Sbjct: 361 KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWVELGGECNINCSKTG 420
Query: 573 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 632
YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK
Sbjct: 421 YSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTK 480
Query: 633 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 692
KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK
Sbjct: 481 KLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEK 540
Query: 693 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 723
EIQWETRLFHEDGECWVYDEPLLKRLGAAKH
Sbjct: 541 EIQWETRLFHEDGECWVYDEPLLKRLGAAKH 571
>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
Length = 747
Score = 437 bits (1123), Expect = e-122
Identities = 214/398 (53%), Positives = 285/398 (71%), Gaps = 20/398 (5%)
Query: 335 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 394
+D ++ D+ D ++DD G+VEE +SVI+HLLSQ++LGMDLT+VVLPTFILE+RSLLEMY
Sbjct: 345 ADDEIEDTCDHKEDDL--GAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMY 402
Query: 395 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 454
ADF +HPDLF++I++ +DRM++ V++YL++FH GRKG++AKKPYNPI+GE F C W
Sbjct: 403 ADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWK 462
Query: 455 LPNDTEENTELVSEGPVPWVSKNS----------------VTFVAEQVSHHPPISAFYAE 498
+P +E + + S V+ ++ V FVAEQVSHHPP+S FYAE
Sbjct: 463 MPK-SEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAE 521
Query: 499 CFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVPWV 558
C +K+ NAH+WTKSKFLGMSIGV +G+G +S L++ E Y + P Y RSILTVPWV
Sbjct: 522 CTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWV 581
Query: 559 ELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYA 618
ELGG+ ++NC+KTGYSA+I FHTKPFYGGK HR+TAE+ C ++GEWN V+
Sbjct: 582 ELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEF 641
Query: 619 KYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRL 678
Y+ GE T +VD KL + KK+VR LE Q+ +ESR LWK+VT +L+ +ID ATE KH L
Sbjct: 642 TYSNGE-TKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTL 700
Query: 679 EERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 716
EERQR E R R E W+T+ F ++G+ WVY +PL K
Sbjct: 701 EERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWK 738
Score = 77.0 bits (188), Expect = 6e-14
Identities = 40/97 (41%), Positives = 58/97 (59%), Gaps = 2/97 (2%)
Query: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
G L K+TN++ GWQYR+FVL+ AGLL Y+ + ++ RG ++L GAVI DED
Sbjct: 63 GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVN-EQSRNQKPRGTLQLAGAVISPSDEDSH 121
Query: 67 TFTI-TVDQKTFHFQARDADEREKWIHALEETILRHT 102
TFT+ + + +A DA ER+ W+ L+ HT
Sbjct: 122 TFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHT 158
>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
sapiens]
Length = 764
Score = 428 bits (1100), Expect = e-119
Identities = 210/420 (50%), Positives = 282/420 (67%), Gaps = 14/420 (3%)
Query: 306 SVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHL 365
++L +S+ +P+ + S L S+ + D+ D ++ E G +E+ +S+I+HL
Sbjct: 348 AILPNSAEDEQTSQPEPEPNSGSELV--LSEDEKSDNEDK--EETELGVMEDQRSIILHL 403
Query: 366 LSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYL 425
+SQ++LGMDLTKVVLPTFILE+RSLLEMYADF AHPDL ++I+ P++R++ V++YL
Sbjct: 404 ISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYL 463
Query: 426 SAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPV-----PWVSKNS-- 478
+AFH GRKG++AKKPYNPI+GE F C W +P D + S P P S
Sbjct: 464 TAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKS 523
Query: 479 --VTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDY 536
+ FVAEQVSHHPPIS FY EC K++ N H+WTKSKF+GMS+GV IG+G + L++
Sbjct: 524 YKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEH 583
Query: 537 DEHYILTFPNGYGRSILTVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEI 596
E Y+ T P+ Y RSILT+PWVELGG+ +INC+KTGYSA +IFHTKPFYGGK HR+TAE+
Sbjct: 584 GEEYVFTLPSAYARSILTIPWVELGGKVSINCAKTGYSATVIFHTKPFYGGKVHRVTAEV 643
Query: 597 FSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYESRSLW 656
C GEWNG + Y GE V +DT LP+ KK+R LE Q ESR+LW
Sbjct: 644 KHNPTNTIVCKAHGEWNGTLEFTYNNGETKV-IDTTTLPVYPKKIRPLEKQGPMESRNLW 702
Query: 657 KDVTFNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHEDGECWVYDEPLLK 716
++VT L++ DIDAATE K LEE+QR E R+R+ W+ + F ++G+ WVY PL K
Sbjct: 703 REVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLWK 762
Score = 70.5 bits (171), Expect = 5e-12
Identities = 34/98 (34%), Positives = 58/98 (59%), Gaps = 2/98 (2%)
Query: 5 MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
+EG LSK+TN+++GWQ R+FVLD+ AG+L Y+ + ++ RG + L GA++ + DE
Sbjct: 77 LEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVN-EQSKHQKPRGVLSLSGAIVSLSDEA 135
Query: 65 DSTFTI-TVDQKTFHFQARDADEREKWIHALEETILRH 101
+ + + + F +A DA E++ W+ L H
Sbjct: 136 PHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYH 173
>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
[Homo sapiens]
Length = 847
Score = 237 bits (604), Expect = 3e-62
Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)
Query: 275 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 334
YS D+ + D+ H S ++ S + T +S P+ E L +
Sbjct: 285 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 340
Query: 335 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 394
S +L ++ + + + EE+KS+I LL QVR GMDL+KVVLPTFILE RS L+
Sbjct: 341 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 397
Query: 395 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 454
+D++ H D + +++P R+ +VVKWYLS F+ KG KKPYNPILGE F+C W
Sbjct: 398 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 455
Query: 455 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 513
P NS TF +AEQVSHHPPISAFY + I K
Sbjct: 456 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 497
Query: 514 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 572
SKF G S+ G+ ++ L+ E Y++T P + + IL +ELGG NI C KTG
Sbjct: 498 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 557
Query: 573 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 628
YSA + F KPF G ++I+ ++ K+ ++EG W+ V T + VF
Sbjct: 558 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 615
Query: 629 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 685
D K+ +I+ V K E+Q ++ES LW+ VT + +D AT+ K+ LEE QR
Sbjct: 616 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 674
Query: 686 ARERKEKEIQWETRLFHED 704
AR+RK K +W +LF D
Sbjct: 675 ARDRKTKNEEWSCKLFELD 693
>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
Length = 889
Score = 237 bits (604), Expect = 3e-62
Identities = 161/439 (36%), Positives = 228/439 (51%), Gaps = 39/439 (8%)
Query: 275 YSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGT 334
YS D+ + D+ H S ++ S + T +S P+ E L +
Sbjct: 327 YSDKSDK--ENDQEHDE--SDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTEQ 382
Query: 335 SDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMY 394
S +L ++ + + + EE+KS+I LL QVR GMDL+KVVLPTFILE RS L+
Sbjct: 383 SHEELGEAGEASQTETVS---EENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKL 439
Query: 395 ADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWT 454
+D++ H D + +++P R+ +VVKWYLS F+ KG KKPYNPILGE F+C W
Sbjct: 440 SDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFYKKPKG--LKKPYNPILGETFRCLWI 497
Query: 455 LPNDTEENTELVSEGPVPWVSKNSVTF-VAEQVSHHPPISAFYAECFNKKIQFNAHIWTK 513
P NS TF +AEQVSHHPPISAFY + I K
Sbjct: 498 HPR------------------TNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAK 539
Query: 514 SKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSIL-TVPWVELGGECNINCSKTG 572
SKF G S+ G+ ++ L+ E Y++T P + + IL +ELGG NI C KTG
Sbjct: 540 SKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQKTG 599
Query: 573 YSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFCSIEGEWNG-VMYAKYATGENTVF- 628
YSA + F KPF G ++I+ ++ K+ ++EG W+ V T + VF
Sbjct: 600 YSAILEFKLKPFLGSSDCVNQISGKL--KLGKEVLATLEGHWDSEVFITDKKTDNSEVFW 657
Query: 629 ---VDTKKLPIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAE 685
D K+ +I+ V K E+Q ++ES LW+ VT + +D AT+ K+ LEE QR
Sbjct: 658 NPTPDIKQWRLIRHTV-KFEEQGDFESEKLWQRVTRAINAKDQTEATQEKYVLEEAQRQA 716
Query: 686 ARERKEKEIQWETRLFHED 704
AR+RK K +W +LF D
Sbjct: 717 ARDRKTKNEEWSCKLFELD 735
>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
[Homo sapiens]
Length = 879
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 267 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 313
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 261 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 320
Query: 314 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 369
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 321 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 378
Query: 370 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 429
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 379 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 438
Query: 430 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 489
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 439 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 479
Query: 490 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 549
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 480 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 539
Query: 550 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 606
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 540 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 597
Query: 607 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 662
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 598 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 657
Query: 663 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 704
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 658 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 699
>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 267 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 313
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 193 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 252
Query: 314 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 369
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 253 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 310
Query: 370 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 429
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 311 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 370
Query: 430 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 489
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 371 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 411
Query: 490 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 549
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
Query: 550 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 606
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 529
Query: 607 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 662
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 530 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 589
Query: 663 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 704
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 221 bits (563), Expect = 2e-57
Identities = 156/462 (33%), Positives = 234/462 (50%), Gaps = 47/462 (10%)
Query: 267 PNTVPEFSYSS------SEDEFYDADEFHQSGSS-------PKRLIDSSGSASVLTHSSS 313
P T P+ S SS S D D F +GSS K ++ + T S
Sbjct: 193 PGTSPDASPSSLCGLPASATVHPDQDLFPLNGSSLENDAFSDKSERENPEESDTETQDHS 252
Query: 314 GNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVE----EHKSVIMHLLSQV 369
+ D +E+ + + GT+ + ++ + EA VE E+KS++ LL Q+
Sbjct: 253 RKTESGSDQSETPGAPVRRGTTYVE--QVQEELGELGEASQVETVSEENKSLMWTLLKQL 310
Query: 370 RLGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFH 429
R GMDL++VVLPTF+LE RS L +D++ H DL + ++D RM V++WYLS F+
Sbjct: 311 RPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFY 370
Query: 430 AGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHH 489
KG KKPYNPILGE F+C W P T+ T ++AEQVSHH
Sbjct: 371 KKPKG--IKKPYNPILGETFRCCWFHP-QTDSRT----------------FYIAEQVSHH 411
Query: 490 PPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYG 549
PP+SAF+ + I KS+F G S+ G+ ++ L+ E Y LT P +
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
Query: 550 RSIL-TVPWVELGGECNINCSKTGYSANIIFHTKPFYGGKK--HRITAEIFSPNDKKSFC 606
+ IL +ELGG+ I C+K + A + F KPF+GG ++I+ +I S ++
Sbjct: 472 KGILYGTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITS--GEEVLA 529
Query: 607 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRK----LEDQNEYESRSLWKDVTFN 662
S+ G W+ ++ K ++ T + ++++R+ LE+Q E ES LW+ VT
Sbjct: 530 SLSGHWDRDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERLWQHVTRA 589
Query: 663 LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHED 704
+ D AT+ K LEE QR ARER+E + W+ +LFH D
Sbjct: 590 ISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLFHLD 631
>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
sapiens]
Length = 950
Score = 164 bits (414), Expect = 3e-40
Identities = 193/784 (24%), Positives = 301/784 (38%), Gaps = 167/784 (21%)
Query: 6 EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSK-DKMMRGSRRGCVRLRGAVIGIDDED 64
EGPL K + GW+ W VL++ G+LS+Y + D + R+GC L AV + D
Sbjct: 239 EGPLWKSSRFF-GWRLFWVVLEH--GVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTD 295
Query: 65 DSTFTITVDQKTFH-FQARD---ADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFD 120
F I T H F+ RE W+ A+EE T QD
Sbjct: 296 SCLFFIKCFDDTIHGFRVPKNSLQQSREDWLEAIEEHSAYSTHYCS----------QD-- 343
Query: 121 KKLTEADAYLQILIEQLKLFDDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLLQIA 180
+LT+ + + LK +K Q+C++ R+ ++ ++ IK C + ++
Sbjct: 344 -QLTDEEEEDTVSAADLKKSLEKAQSCQQRLDRE--------ISNFLKMIKECDMAKEML 394
Query: 181 KSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLPV-GPVLATLGHHQ 239
S + V+ + + S V T E V+ K EQ + L TL
Sbjct: 395 PSFLQKVEVVSEASRETCVALTDCLNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEH 454
Query: 240 TPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLI 299
S G SPP+S L SEDEFYDA S S +R +
Sbjct: 455 HELEQSLVKG-SPPASIL--------------------SEDEFYDA----LSDSESERSL 489
Query: 300 DSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDRDDDAEAGSVEEHK 359
+ + + G L G+ + + D DA + +++H+
Sbjct: 490 SRLEAVTARSFEEEGEHL---------------GSRKHRMSEEKDCGGGDALSNGIKKHR 534
Query: 360 SVI---------MHLLSQVR--LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSIS 408
+ + + S +R +GM+L+K+ +P E S L+ ++ H L S
Sbjct: 535 TSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKAS 594
Query: 409 DQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSE 468
DP +RM V + +SA + KP+NP+LGE + ELV +
Sbjct: 595 SLSDPVERMQCVAAFAVSA--VASQWERTGKPFNPLLGETY--------------ELVRD 638
Query: 469 GPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQ 528
++EQVSHHPPISAF+AE N F+ I+ K KF G S+ G
Sbjct: 639 -------DLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGT 691
Query: 529 GCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGG 587
+ L+++E Y T P +I+ W+E G I KTG + F +G
Sbjct: 692 ITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGK 751
Query: 588 KKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQ 647
+ H++ I KK C++ G+W +Y+ + + KK KK +++
Sbjct: 752 ELHKVEGYI-QDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTS 810
Query: 648 NEYE---------------SRSLWK----------------------------------- 657
E + S LW+
Sbjct: 811 EELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKT 870
Query: 658 DVTFNLKIR-----DIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHE------DGE 706
D IR +ID A+E K RLEE+QRA + R + E W+TR FH+ +
Sbjct: 871 DCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQ 930
Query: 707 CWVY 710
W+Y
Sbjct: 931 DWIY 934
>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
sapiens]
Length = 437
Score = 124 bits (310), Expect = 4e-28
Identities = 106/402 (26%), Positives = 161/402 (40%), Gaps = 86/402 (21%)
Query: 371 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 430
+GM+L+K+ +P E S L+ ++ H L S DP +RM V + +SA
Sbjct: 44 IGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSA--V 101
Query: 431 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 490
+ KP+NP+LGE + ELV + ++EQVSHHP
Sbjct: 102 ASQWERTGKPFNPLLGETY--------------ELVRDDL-------GFRLISEQVSHHP 140
Query: 491 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 550
PISAF+AE N F+ I+ K KF G S+ G + L+++E Y T P
Sbjct: 141 PISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVH 200
Query: 551 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 609
+I+ W+E G I KTG + F +G + H++ I KK C++
Sbjct: 201 NIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYI-QDKSKKKLCALY 259
Query: 610 GEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLEDQNEYE---------------SRS 654
G+W +Y+ + + KK KK +++ E + S
Sbjct: 260 GKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVL 319
Query: 655 LWK-----------------------------------DVTFNLKIR-----DIDAATEA 674
LW+ D IR +ID A+E
Sbjct: 320 LWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEE 379
Query: 675 KHRLEERQRAEARERKEKEIQWETRLFHE------DGECWVY 710
K RLEE+QRA + R + E W+TR FH+ + W+Y
Sbjct: 380 KKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIY 421
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 115 bits (287), Expect = 2e-25
Identities = 182/755 (24%), Positives = 300/755 (39%), Gaps = 134/755 (17%)
Query: 3 SIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDD 62
S EG L KWTN +KG+Q RWFVL + GLLSYY SK + MR + RG + L A I
Sbjct: 89 SAREGWLFKWTNYIKGYQRRWFVL--SNGLLSYYRSKAE-MRHTCRGTINL--ATANITV 143
Query: 63 EDDSTFTIT-VDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLD-SGFVPSVQDFD 120
ED F I+ +T+H +A ER++W+ ALE + L D SG SV D
Sbjct: 144 EDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTD 203
Query: 121 KKLTEADAYLQIL---IEQLKLFDDKLQNCKEDEQR--KKIETLK--ETTNSMVESIKHC 173
K TE L+ L +E L +D + QR ++E+LK +N ++ +
Sbjct: 204 K--TELQNTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLKLPAESNEKIKQVNER 261
Query: 174 IVLLQI-AKSTINP-----VDAIYQPSPLEPVISTMPSQTVLPPEPV-QLCKSEQRPSSL 226
L +I + + IN + A + + Q + E + QL K
Sbjct: 262 ATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERA 321
Query: 227 PVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDAD 286
G + TP + GSG S + S E+EF+DA
Sbjct: 322 FRGATVLPAN-----TPGNVGSGKDQCCSG-------------KGDMSDEDDENEFFDAP 363
Query: 287 EFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNGTSDADLFDSHDDR 346
E + L H +G S++S +SD L + + +
Sbjct: 364 EIITMPEN-------------LGHKRTG-------------SNISGASSDISLDEQYKHQ 397
Query: 347 DDDAEAGS-----VEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFFAHP 401
++ + + + S+ + + + +G +L+K+ +P E S+L+ + +
Sbjct: 398 LEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYH 457
Query: 402 DLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPNDTEE 461
+L + ++ +++ V + +S++ KP+NP+LGE F+
Sbjct: 458 ELLDRAAKCENSLEQLCYVAAFTVSSY--STTVFRTSKPFNPLLGETFE----------- 504
Query: 462 NTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSI 521
+ + +N + EQVSHHPP +A +AE N I SKF G +
Sbjct: 505 ---------LDRLEENGYRSLCEQVSHHPPAAAHHAESKN-GWTLRQEIKITSKFRGKYL 554
Query: 522 GVHNIGQGCVSCLDY--DEHYILTFPNGYGRSILTVP-WVELGGECNINCSKTGYSANII 578
+ + G + C+ + HY +I+ W++ GE +I KTG N+
Sbjct: 555 SIMPL--GTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLK 612
Query: 579 FHTKPFYG-GKKHRITAEIFSPNDKKSFCSIEGEWNGVM---YAKYATGEN-------TV 627
F ++ ++T E+ P+ K F ++ G W+ M + GEN
Sbjct: 613 FVPYSYFSRDVARKVTGEVTDPSGKVHF-ALLGTWDEKMECFKVQPVIGENGGDARQRGH 671
Query: 628 FVDTKKLPIIKKKVRKLEDQNEYESRSL------WKDVTFNLKIR-----------DIDA 670
+ ++ + K+ +N Y L W+ T R D
Sbjct: 672 EAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWESGTAPTDSRLRPDQRLMENGRWDE 731
Query: 671 ATEAKHRLEERQRAEARERKEKEIQWETRLFHEDG 705
A K RLEE+QR +R+++E E T EDG
Sbjct: 732 ANAEKQRLEEKQRL-SRKKREAEAMKAT----EDG 761
>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
[Homo sapiens]
Length = 480
Score = 109 bits (273), Expect = 8e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 371 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 430
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 84 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 141
Query: 431 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 490
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 142 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 180
Query: 491 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 550
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 181 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 240
Query: 551 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 609
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 241 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 299
Query: 610 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 645
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 300 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 359
Query: 646 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 673
+ S ++ +F + + +++ E
Sbjct: 360 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 419
Query: 674 --AKHRLEERQRAEARERKEKEIQWETRLFH 702
K RLEE+QR RER ++E +W+TR F+
Sbjct: 420 SQEKERLEEKQREARRERAKEEAEWQTRWFY 450
>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
sapiens]
Length = 468
Score = 109 bits (273), Expect = 8e-24
Identities = 95/391 (24%), Positives = 160/391 (40%), Gaps = 83/391 (21%)
Query: 371 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 430
+G++L+K+ +P E S L+ ++ H L S Q P +RM V + +SA
Sbjct: 72 VGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQSVAAFAVSA--V 129
Query: 431 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 490
+ KP+NP+LGE + EL+ E F++EQVSHHP
Sbjct: 130 ASQWERTGKPFNPLLGETY--------------ELIREDL-------GFRFISEQVSHHP 168
Query: 491 PISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGR 550
PISAF++E N F+ I+ K KF G S+ G + L ++E Y T P
Sbjct: 169 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 228
Query: 551 SILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIE 609
+++ W+E G I +TG+ + F +G + H++ I N KK F I
Sbjct: 229 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF-MIY 287
Query: 610 GEWNGVMYA--------------------KYATGENTVFVDT---KKLPIIKKKVRKLE- 645
G+W ++ K E++ D+ +P+ ++ V+ +
Sbjct: 288 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 347
Query: 646 -------DQNEYESRSLWKDVTFNLKIRDIDAATE------------------------- 673
+ S ++ +F + + +++ E
Sbjct: 348 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 407
Query: 674 --AKHRLEERQRAEARERKEKEIQWETRLFH 702
K RLEE+QR RER ++E +W+TR F+
Sbjct: 408 SQEKERLEEKQREARRERAKEEAEWQTRWFY 438
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 104 bits (260), Expect = 3e-22
Identities = 175/757 (23%), Positives = 282/757 (37%), Gaps = 156/757 (20%)
Query: 6 EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDD 65
EG L KWTN +KG+Q RWFVL GLLSYY ++ +M + RG + L A ID ED
Sbjct: 186 EGWLLKWTNYLKGYQRRWFVL--GNGLLSYYRNQGEMAH-TCRGTINLSTA--HIDTEDS 240
Query: 66 STFTITVDQKTFHFQARDADEREKWIHALEETILR--HTLQLQGLDSGFVPSVQDFDKKL 123
+T +++H +A +R++WI ALE + + DSG D D+
Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSG------DDDEAT 294
Query: 124 TEAD-AYLQILIEQLKLFDDKLQNCKE----------------------DEQRKKIETLK 160
T AD + L ++ L L D L C + E +K++ +
Sbjct: 295 TPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVN 354
Query: 161 E-------TTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEP 213
E T+N+M+ + C L++A+ I + Q L E
Sbjct: 355 ERATLFRITSNAMINA---CRDFLELAE------------------IHSRKWQRALQYEQ 393
Query: 214 VQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEF 273
Q E+ L H P + S S LT E
Sbjct: 394 EQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKG----------ED 443
Query: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDT-TESLN-SSLS 331
S + E++DA E DS+ +V+T + + T T S++ SS
Sbjct: 444 SEEDEDTEYFDAME------------DSTSFITVITEAKEDSRKAEGSTGTSSVDWSSAD 491
Query: 332 NGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLL 391
N A L + + + S+ + + + +G +L+++ +P E S+L
Sbjct: 492 NVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSML 551
Query: 392 EMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQC 451
+ + + L ++M V + +S++ KP+NP+LGE F+
Sbjct: 552 QRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSY--STTVHRIAKPFNPMLGETFEL 609
Query: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511
D ++ L S + EQVSHHPP +A Y F+ H W
Sbjct: 610 ------DRLDDMGLRS--------------LCEQVSHHPPSAAHYV--------FSKHGW 641
Query: 512 T-------KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGE 563
+ SKF G I + +G + HY+ +I+ W++ G+
Sbjct: 642 SLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGD 701
Query: 564 CNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEW------NGVMY 617
I KT + F ++ + R + S + K+ + G W + VM+
Sbjct: 702 IEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMH 761
Query: 618 AKYAT----GENTVFVDTKKLPIIKKKVRKLEDQ-------------NEYE------SRS 654
+ ++ G+ T ++ KK E+ NE+E
Sbjct: 762 SSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSR 821
Query: 655 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKE 691
L D K R +A TE K RLEE+QR R R E
Sbjct: 822 LRPDQRLMEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857
>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
[Homo sapiens]
Length = 938
Score = 99.4 bits (246), Expect = 1e-20
Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)
Query: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333
S S S EF+DA E S SS + ++S S ++ S S ++++ + NG
Sbjct: 491 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 548
Query: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393
F + R A + + ++L +G DL+KV +P + E + L+
Sbjct: 549 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 605
Query: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451
+ + +L S+ DP +RMV V + +S + + R GS KP+NP+LGE ++C
Sbjct: 606 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 662
Query: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511
+ E F +EQVSHHPPISA C +K F I
Sbjct: 663 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 699
Query: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 570
K+KF G S+ + +G V Y ++Y+ +IL+ W+E GE I +K
Sbjct: 700 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 759
Query: 571 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 628
+ + K Y + + K+ + G+W+ +Y A ++
Sbjct: 760 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 819
Query: 629 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 670
++ +L P++K + + + + R L + +++A
Sbjct: 820 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 871
Query: 671 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 712
A K R+EE QR+ R +E ++ + F + E WV ++
Sbjct: 872 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 918
Score = 34.7 bits (78), Expect = 0.32
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVLD G+L Y + + +G G + + +V+ I + +
Sbjct: 77 KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 131
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + D + W+ L
Sbjct: 132 DTEEHIYHLKVKSQDWFDAWVSKL 155
>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
[Homo sapiens]
Length = 934
Score = 99.4 bits (246), Expect = 1e-20
Identities = 109/467 (23%), Positives = 191/467 (40%), Gaps = 67/467 (14%)
Query: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333
S S S EF+DA E S SS + ++S S ++ S S ++++ + NG
Sbjct: 487 SMSESVSEFFDAQEVLLSASSSEN--EASDDESYISDVSDNISEDNTSVADNISRQILNG 544
Query: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393
F + R A + + ++L +G DL+KV +P + E + L+
Sbjct: 545 ELTGGAF--RNGRRACLPAPCPDTSNINLWNILRN-NIGKDLSKVSMPVELNEPLNTLQH 601
Query: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451
+ + +L S+ DP +RMV V + +S + + R GS KP+NP+LGE ++C
Sbjct: 602 LCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGS---KPFNPVLGETYEC 658
Query: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511
+ E F +EQVSHHPPISA C +K F I
Sbjct: 659 --------------IRE-------DKGFRFFSEQVSHHPPISA--CHCESKNFVFWQDIR 695
Query: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNINCSK 570
K+KF G S+ + +G V Y ++Y+ +IL+ W+E GE I +K
Sbjct: 696 WKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTK 755
Query: 571 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVF-- 628
+ + K Y + + K+ + G+W+ +Y A ++
Sbjct: 756 SSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRP 815
Query: 629 -----------------VDTKKL-PIIKKKVRKLEDQNEYESRSLWKDVTFNLKIRDIDA 670
++ +L P++K + + + + R L + +++A
Sbjct: 816 GSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEG--------NLEA 867
Query: 671 ATEAKHRLEERQRAEARERKEKEIQWETRLFHE-----DGECWVYDE 712
A K R+EE QR+ R +E ++ + F + E WV ++
Sbjct: 868 AASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSND 914
Score = 34.7 bits (78), Expect = 0.32
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVLD G+L Y + + +G G + + +V+ I + +
Sbjct: 98 KWP--LKGWHKRFFVLD--NGMLKYSKAPLDIQKGKVHGSIDVGLSVMSI-KKKARRIDL 152
Query: 71 TVDQKTFHFQARDADEREKWIHAL 94
++ +H + + D + W+ L
Sbjct: 153 DTEEHIYHLKVKSQDWFDAWVSKL 176
>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
[Homo sapiens]
Length = 820
Score = 99.4 bits (246), Expect = 1e-20
Identities = 178/802 (22%), Positives = 301/802 (37%), Gaps = 141/802 (17%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADAYL 130
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLRH----HRMYRQNEIAMFPHEVNHFFSGSTITDSSS 173
Query: 131 QIL----------IEQLKLFDDKLQ---NCKEDEQRKKIETLKETTNSMVESIKHCIVLL 177
+ I + LF +C + + E + + HC L
Sbjct: 174 GVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYL 233
Query: 178 QIAKSTINPVDAIYQPSPLEPVISTMPSQTVLP-PEPVQLCKSEQRPSSLPVGPVLATLG 236
+ +D +++ P I+ + Q P PV+L S S+L G
Sbjct: 234 VEMSQLLQSMDVLHRTYSA-PAINAI--QVPKPFSGPVRLHSSNPNLSTLDFGE------ 284
Query: 237 HHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSP- 295
+ T S S L +H + F+ S+E E + SSP
Sbjct: 285 EKNYSDGSETSSEFSKMQEDLCHIAH-KVYFTLRSAFNIMSAEREKLKQLMEQDASSSPS 343
Query: 296 ------KRLIDSSGSAS---VLTHSSSGNSLKRPDTTESLN------------SSLSNGT 334
K + S S L H S S R T+SL+ SS N
Sbjct: 344 AQVIGLKNALSSENSRDENRALVHQLSNES--RLSITDSLSEFFDAQEVLLSPSSSENEI 401
Query: 335 SDADLF--DSHDDRDDDAEAGSVEEHKSVIMHLLSQVR---------------------- 370
SD D + D D+ D + ++ + + +L R
Sbjct: 402 SDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISL 461
Query: 371 -------LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKW 423
+G DL+KV +P + E + L+ + + +L + P +RMV V +
Sbjct: 462 WNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAF 521
Query: 424 YLSAFHAG--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 481
+SA+ + R GS KP+NP+LGE ++C + E F
Sbjct: 522 AISAYASSYYRAGS---KPFNPVLGETYEC--------------IRED-------KGFQF 557
Query: 482 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 541
+EQVSHHPPISA +AE ++ F + K+KF G S+ + IG V+ + +H+
Sbjct: 558 FSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFE 615
Query: 542 LTFPNGYGRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRITAEIFSP 599
+IL+ W+E GE I N + F ++ H I +F
Sbjct: 616 WNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFD- 674
Query: 600 NDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE------DQNEYE-- 651
K+ + G+W+ +Y + V+ + P+ K + + NE +
Sbjct: 675 RSGKAVHRLFGKWHESIYCGGGSSSACVW---RANPMPKGYEQYYSFTQFALELNEMDPS 731
Query: 652 SRSLW--KDVTFN-----LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHE- 703
S+SL D F L+ +++ A K R+E+ QR R +E ++ + R F +
Sbjct: 732 SKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKS 791
Query: 704 DGECWVYDEPLL---KRLGAAK 722
D + WV + L K LG +K
Sbjct: 792 DDDSWVSNGTYLELRKDLGFSK 813
>gi|54792084 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 3 [Homo
sapiens]
Length = 300
Score = 92.0 bits (227), Expect = 2e-18
Identities = 82/303 (27%), Positives = 138/303 (45%), Gaps = 37/303 (12%)
Query: 5 MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
MEG L KWTN + GWQ RWFVLD G+LSYY S+D + +GS +G +++ I + D
Sbjct: 1 MEGVLYKWTNYLTGWQPRWFVLD--NGILSYYDSQDDVCKGS-KGSIKMAVCEIKVHSAD 57
Query: 65 DSTFTITV-DQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKL 123
++ + + ++ F+ +A +A ER++W+ AL + T + + + K+
Sbjct: 58 NTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKM 117
Query: 124 TEADAYLQILIEQLKLF------DDKLQNCKEDEQRKKIETLKETTNSMVESIKHCIVLL 177
+E Y +L++Q+ D+ + + + L T N+ + +++ C+
Sbjct: 118 SELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECV--- 174
Query: 178 QIAKSTINP-VDAIYQPSPLEPVISTMPSQ----TVLPPEPVQLCKSEQRPSSL--PVGP 230
+IA + P + ++ P PL +S P Q +V P C SE+ S+ PV
Sbjct: 175 KIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGS---CSSERSSHSIKEPVS- 230
Query: 231 VLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHV-------NLSPNTVPEFS------YSS 277
L L + T + T S P P H +L+ T+PE S S
Sbjct: 231 TLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSE 290
Query: 278 SED 280
SED
Sbjct: 291 SED 293
>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
[Homo sapiens]
Length = 851
Score = 89.7 bits (221), Expect = 8e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
Query: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
Query: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
Query: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
Query: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 569
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
Query: 570 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 629
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
Query: 630 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 674
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
Query: 675 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 722
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
Score = 38.9 bits (89), Expect = 0.017
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
[Homo sapiens]
Length = 856
Score = 89.7 bits (221), Expect = 8e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 412 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 467
Query: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 468 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 527
Query: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 528 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 584
Query: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 585 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 621
Query: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 569
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 622 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 681
Query: 570 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 629
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 682 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 739
Query: 630 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 674
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 740 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 797
Query: 675 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 722
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 798 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 849
Score = 38.9 bits (89), Expect = 0.017
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
[Homo sapiens]
Length = 887
Score = 89.7 bits (221), Expect = 8e-18
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 443 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 498
Query: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 499 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 558
Query: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 559 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 615
Query: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 616 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 652
Query: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 569
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 653 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 712
Query: 570 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 629
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 713 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 770
Query: 630 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 674
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 771 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 828
Query: 675 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 722
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 829 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 880
Score = 38.9 bits (89), Expect = 0.017
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
Length = 842
Score = 85.9 bits (211), Expect = 1e-16
Identities = 87/347 (25%), Positives = 145/347 (41%), Gaps = 43/347 (12%)
Query: 371 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 430
+G DL+KV +P + E + L+ + + L S DP +RMV + + +SA+ +
Sbjct: 487 IGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYSS 546
Query: 431 G--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSH 488
R G KP+NP+LGE ++C E P F++EQVSH
Sbjct: 547 TYHRAGC---KPFNPVLGETYEC----------------ERP-----DRGFRFISEQVSH 582
Query: 489 HPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGY 548
HPPISA +AE ++ F + K+KF G S+ + +G VS + +H+
Sbjct: 583 HPPISACHAE--SENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSC 640
Query: 549 GRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFC 606
++L+ W+E GE I N + I F ++ H + + S +
Sbjct: 641 IHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLS-RSGRVLH 699
Query: 607 SIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKK------VRKLEDQNEYESRSLWKDVT 660
+ G+W+ +Y G ++ P ++ +L + RSL T
Sbjct: 700 RLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDT 759
Query: 661 ------FNLKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLF 701
L+ +I AA K R+E+ QR + +E I + R F
Sbjct: 760 RLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFF 806
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
KW +KGW R+FVL+ G+L Y T++ + +G G + +R +V+ I ++ +
Sbjct: 59 KWP--LKGWHKRYFVLE--DGILHYATTRQDITKGKLHGSIDVRLSVMSI-NKKAQRIDL 113
Query: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQL 105
+ +H + + D + W+ L L H L +
Sbjct: 114 DTEDNIYHLKIKSQDLFQSWVAQLRAHRLAHRLDM 148
>gi|14249174 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 8 [Homo
sapiens]
Length = 440
Score = 84.0 bits (206), Expect = 5e-16
Identities = 56/210 (26%), Positives = 105/210 (50%), Gaps = 10/210 (4%)
Query: 5 MEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDED 64
MEG L KWTN + GWQ RWF+L G+LSYY S + +G +G +++ I + D
Sbjct: 1 MEGVLYKWTNYLSGWQPRWFLL--CGGILSYYDSPEDAWKGC-KGSIQMAVCEIQVHSVD 57
Query: 65 DSTFTITV-DQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKL 123
++ + + ++ F+ +AR ER++W+ AL T + F + ++ K+
Sbjct: 58 NTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKM 117
Query: 124 TEADAYLQILIEQL-KLFDDKLQNCKEDEQRKKIET-LKETTNSMVESIKHCIVLLQIAK 181
+E Y +L++Q+ K + E+ + T LK T N+ +++++ C +QIA
Sbjct: 118 SELRLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEEC---MQIAN 174
Query: 182 STINPVDAIYQPSPLEPVISTMPSQTVLPP 211
+ + +Y+ P P ++ + S + P
Sbjct: 175 AAFTS-ELLYRTPPGSPQLAMLKSSKMKHP 203
>gi|14165452 alpha 3 type IV collagen binding protein isoform 2
[Homo sapiens]
Length = 598
Score = 82.8 bits (203), Expect = 1e-15
Identities = 62/175 (35%), Positives = 84/175 (48%), Gaps = 28/175 (16%)
Query: 7 GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66
G LSKWTN + GWQ RW VL NA LSYY S+D+ G R G + L AVI D D+
Sbjct: 28 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 84
Query: 67 TFTITVDQKTFHFQARDADEREKWIHALE----------ETILRHTLQLQGLDSG----F 112
F I+V+ ++ +A+D D R++WI A+E E+ LR + L SG
Sbjct: 85 RFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYS 144
Query: 113 VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDEQRKKI 156
S F K KL E + + IL Q+ C K++ QR K+
Sbjct: 145 ATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKV 199
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,042,767
Number of Sequences: 37866
Number of extensions: 1432771
Number of successful extensions: 8370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 236
Number of HSP's that attempted gapping in prelim test: 7291
Number of HSP's gapped (non-prelim): 1096
length of query: 723
length of database: 18,247,518
effective HSP length: 110
effective length of query: 613
effective length of database: 14,082,258
effective search space: 8632424154
effective search space used: 8632424154
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.