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Search of human proteins with 224967057
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224967057 fast-twitch skeletal muscle troponin I isoform 1
[Homo sapiens]
(182 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507621 fast-twitch skeletal muscle troponin I isoform 1 [Hom... 362 e-101
gi|224967057 fast-twitch skeletal muscle troponin I isoform 1 [H... 362 e-101
gi|224967106 fast-twitch skeletal muscle troponin I isoform 2 [H... 353 6e-98
gi|56682969 troponin I, skeletal, slow [Homo sapiens] 208 2e-54
gi|151101270 troponin I, cardiac [Homo sapiens] 204 4e-53
gi|156104908 myosin heavy chain 6 [Homo sapiens] 44 1e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens] 42 3e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 42 3e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens] 42 3e-04
gi|7705415 hook homolog 1 [Homo sapiens] 42 4e-04
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 40 0.001
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 40 0.001
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 39 0.002
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 39 0.002
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 39 0.002
gi|46852174 kinesin family member 3A [Homo sapiens] 39 0.002
gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein... 38 0.005
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.007
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.007
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 37 0.007
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 37 0.007
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.012
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 37 0.012
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 37 0.012
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 36 0.016
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 36 0.016
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 36 0.016
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 36 0.016
gi|34878777 ring finger protein 20 [Homo sapiens] 36 0.016
gi|238908495 similar to pleckstrin homology domain protein (5V32... 36 0.021
>gi|4507621 fast-twitch skeletal muscle troponin I isoform 1 [Homo
sapiens]
Length = 182
Score = 362 bits (930), Expect = e-101
Identities = 182/182 (100%), Positives = 182/182 (100%)
Query: 1 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
Sbjct: 1 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
Query: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
Sbjct: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
Query: 121 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
Sbjct: 121 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
Query: 181 ES 182
ES
Sbjct: 181 ES 182
>gi|224967057 fast-twitch skeletal muscle troponin I isoform 1 [Homo
sapiens]
Length = 182
Score = 362 bits (930), Expect = e-101
Identities = 182/182 (100%), Positives = 182/182 (100%)
Query: 1 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
Sbjct: 1 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
Query: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
Sbjct: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
Query: 121 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
Sbjct: 121 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
Query: 181 ES 182
ES
Sbjct: 181 ES 182
>gi|224967106 fast-twitch skeletal muscle troponin I isoform 2 [Homo
sapiens]
Length = 182
Score = 353 bits (905), Expect = 6e-98
Identities = 178/182 (97%), Positives = 179/182 (98%)
Query: 1 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
M +KRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE
Sbjct: 1 MSQCKKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
Query: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD
Sbjct: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
Query: 121 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES
Sbjct: 121 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
Query: 181 ES 182
ES
Sbjct: 181 ES 182
>gi|56682969 troponin I, skeletal, slow [Homo sapiens]
Length = 187
Score = 208 bits (530), Expect = 2e-54
Identities = 106/181 (58%), Positives = 138/181 (76%), Gaps = 2/181 (1%)
Query: 1 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMS 59
M + E++ + +R+ LKS+ML A E+E REAEK YLAE P L G S+S
Sbjct: 1 MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLS 60
Query: 60 EVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSA 119
+Q+LC++LHAK++ +EE+YD+E + ++E++D+ K+ DLRGKFKRPPLRRVR+SA
Sbjct: 61 ALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSA 120
Query: 120 DAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE 179
DAML+ALLGSKHKV MDLRANLK VKKEDTEKER + +VGDWRKN+E SGMEGRKKMF+
Sbjct: 121 DAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPV-EVGDWRKNVEAMSGMEGRKKMFD 179
Query: 180 S 180
+
Sbjct: 180 A 180
>gi|151101270 troponin I, cardiac [Homo sapiens]
Length = 210
Score = 204 bits (518), Expect = 4e-53
Identities = 101/177 (57%), Positives = 135/177 (76%), Gaps = 3/177 (1%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPG-SMSEVQE 63
+K+++ +R+ LK+++LQIA ELE+E R EK L+ C PL + G +E+Q+
Sbjct: 36 KKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQD 95
Query: 64 LCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAML 123
LC+QLHA++D +EE+YD+E +V K E+ D+ QK+FDLRGKFKRP LRRVR+SADAM+
Sbjct: 96 LCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMM 155
Query: 124 KALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
+ALLG++ K +DLRA+LKQVKKEDTEKE R+VGDWRKNI+ SGMEGRKK FES
Sbjct: 156 QALLGARAKESLDLRAHLKQVKKEDTEKEN--REVGDWRKNIDALSGMEGRKKKFES 210
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 43.5 bits (101), Expect = 1e-04
Identities = 44/195 (22%), Positives = 93/195 (47%), Gaps = 24/195 (12%)
Query: 3 DEEKRNRAITARRQHLKSVM---------LQIAATELEKEESRREAEKQNYLAEHCPPLH 53
DEE+ N +TA+++ L+ L++ ++EKE+ E + +N E
Sbjct: 930 DEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE------ 983
Query: 54 IPGSMSEVQELCKQLHAKIDAAEEEKYDMEV---RVQKTSKELEDMNQKLFDLRGKFKRP 110
+ G + +L K+ A +A ++ D++V +V SK + Q++ DL G ++
Sbjct: 984 MAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQE 1043
Query: 111 PLRRVRMSADAMLKALLGS---KHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEE 167
++VRM + + L G + MDL + Q++++ +KE D+ + E+
Sbjct: 1044 --KKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNS-KIEDEQ 1100
Query: 168 KSGMEGRKKMFESES 182
++ +KK+ E+++
Sbjct: 1101 VLALQLQKKLKENQA 1115
Score = 39.3 bits (90), Expect = 0.002
Identities = 41/175 (23%), Positives = 75/175 (42%), Gaps = 24/175 (13%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
D+ K N AI RR +L L+ +E+ E R+ +Q + E
Sbjct: 1667 DDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELI--------------ETS 1712
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM 122
E + LH++ + +K ME + + E+E+ Q+ + K K+ DA
Sbjct: 1713 ERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKA-------ITDA- 1764
Query: 123 LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKM 177
A++ + K D A+L+++KK + +DL+ D + I K G + +K+
Sbjct: 1765 --AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKL 1817
Score = 30.4 bits (67), Expect = 0.88
Identities = 26/120 (21%), Positives = 57/120 (47%), Gaps = 13/120 (10%)
Query: 66 KQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKA 125
K+L K+ + +EK D++++VQ L D ++ L + ++ +A +K
Sbjct: 873 KELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERC---------DQLIKNKIQLEAKVKE 923
Query: 126 L---LGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIE-EKSGMEGRKKMFESE 181
+ L + ++ +L A ++++ E +E ++D+ D+ +E EK E + K E
Sbjct: 924 MNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 983
Score = 27.3 bits (59), Expect = 7.4
Identities = 44/210 (20%), Positives = 93/210 (44%), Gaps = 30/210 (14%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAE----KQNYLAE--HCPPLHIPG 56
D E+ R + + + ++ + +L+ EE ++ E +QN E L +
Sbjct: 1049 DLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQK 1108
Query: 57 SMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRG---------KF 107
+ E Q ++L +++A + +E S+ELE+++++L + G K
Sbjct: 1109 KLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKK 1168
Query: 108 KRPPLRRVRMS-ADAMLK-----ALLGSKHKVCM----DLRANLKQVK----KEDTEKER 153
+ +++R +A L+ A L KH + + NL++VK KE +E +
Sbjct: 1169 REAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 1228
Query: 154 DLRDV-GDWRKNIEEKSGMEGRKKMFESES 182
+L DV + + I+ K+ +E + E ++
Sbjct: 1229 ELDDVTSNMEQIIKAKANLEKVSRTLEDQA 1258
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/181 (22%), Positives = 82/181 (45%), Gaps = 23/181 (12%)
Query: 5 EKRNRAITARRQHLKSV-------MLQIAATELEKEESRRE-----AEKQNYLAEHCPPL 52
E+ + I + + LK+V ++Q+A E E R E E Q+ A+ +
Sbjct: 731 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQV 790
Query: 53 HIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPL 112
+ E++++ + KI + EE ++V K ++D+ Q++ L+ + L
Sbjct: 791 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQL 850
Query: 113 RRVRM----SADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEK 168
+ + S L+ LL K + ++A L+ EKE+DL + G W ++++E+
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLE-------EKEKDLANTGKWLQDLQEE 903
Query: 169 S 169
+
Sbjct: 904 N 904
Score = 37.0 bits (84), Expect = 0.009
Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 9/167 (5%)
Query: 6 KRNRAITARRQHLKSVMLQIAATE-----LEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
+++ I + + L++ +L++A E L++E + E N E L I + E
Sbjct: 805 EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQE 864
Query: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
+Q L K +++ + + E + T K L+D+ ++ L+ + ++ ++
Sbjct: 865 LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASS 924
Query: 121 AM----LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRK 163
A L+ +L K L A LK+ + + + K + L+DV D K
Sbjct: 925 ASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENK 971
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/181 (22%), Positives = 82/181 (45%), Gaps = 23/181 (12%)
Query: 5 EKRNRAITARRQHLKSV-------MLQIAATELEKEESRRE-----AEKQNYLAEHCPPL 52
E+ + I + + LK+V ++Q+A E E R E E Q+ A+ +
Sbjct: 731 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQV 790
Query: 53 HIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPL 112
+ E++++ + KI + EE ++V K ++D+ Q++ L+ + L
Sbjct: 791 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQL 850
Query: 113 RRVRM----SADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEK 168
+ + S L+ LL K + ++A L+ EKE+DL + G W ++++E+
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLE-------EKEKDLANTGKWLQDLQEE 903
Query: 169 S 169
+
Sbjct: 904 N 904
Score = 37.0 bits (84), Expect = 0.009
Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 9/167 (5%)
Query: 6 KRNRAITARRQHLKSVMLQIAATE-----LEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
+++ I + + L++ +L++A E L++E + E N E L I + E
Sbjct: 805 EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQE 864
Query: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
+Q L K +++ + + E + T K L+D+ ++ L+ + ++ ++
Sbjct: 865 LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASS 924
Query: 121 AM----LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRK 163
A L+ +L K L A LK+ + + + K + L+DV D K
Sbjct: 925 ASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENK 971
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/181 (22%), Positives = 82/181 (45%), Gaps = 23/181 (12%)
Query: 5 EKRNRAITARRQHLKSV-------MLQIAATELEKEESRRE-----AEKQNYLAEHCPPL 52
E+ + I + + LK+V ++Q+A E E R E E Q+ A+ +
Sbjct: 731 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQV 790
Query: 53 HIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPL 112
+ E++++ + KI + EE ++V K ++D+ Q++ L+ + L
Sbjct: 791 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQL 850
Query: 113 RRVRM----SADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEK 168
+ + S L+ LL K + ++A L+ EKE+DL + G W ++++E+
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLE-------EKEKDLANTGKWLQDLQEE 903
Query: 169 S 169
+
Sbjct: 904 N 904
Score = 37.0 bits (84), Expect = 0.009
Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 9/167 (5%)
Query: 6 KRNRAITARRQHLKSVMLQIAATE-----LEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
+++ I + + L++ +L++A E L++E + E N E L I + E
Sbjct: 805 EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQE 864
Query: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
+Q L K +++ + + E + T K L+D+ ++ L+ + ++ ++
Sbjct: 865 LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASS 924
Query: 121 AM----LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRK 163
A L+ +L K L A LK+ + + + K + L+DV D K
Sbjct: 925 ASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENK 971
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 41.6 bits (96), Expect = 4e-04
Identities = 30/127 (23%), Positives = 63/127 (49%), Gaps = 12/127 (9%)
Query: 58 MSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRM 117
+ E+QE +Q H K++ E E+ + R+++ +++ED+ + L + K + +++
Sbjct: 489 IEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQ 548
Query: 118 SADAMLKAL------LGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGM 171
+A ++ L L K ++ DL+ ++ Q ++ E E L +K E+ M
Sbjct: 549 KLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAAL------QKKDEDMKAM 602
Query: 172 EGRKKMF 178
E R KM+
Sbjct: 603 EERYKMY 609
Score = 32.0 bits (71), Expect = 0.30
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 17/85 (20%)
Query: 26 AATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVR 85
A ELE++ R E Q LAE E+++ C++L ++ ++EK +
Sbjct: 172 AVGELEQQLKRALEELQEALAEK----------EELRQRCEELDMQVTTLQDEKNSL--- 218
Query: 86 VQKTSKELEDMNQKLFDLRGKFKRP 110
E E MN+KL L G F P
Sbjct: 219 ----VSENEMMNEKLDQLDGSFDDP 239
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 40.0 bits (92), Expect = 0.001
Identities = 36/139 (25%), Positives = 68/139 (48%), Gaps = 7/139 (5%)
Query: 31 EKEESRREAEKQNYLAEHC--PPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQK 88
+ E+ R+ +++ LAE L ++ EV+ Q A + AEE ++E R+++
Sbjct: 359 QTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQ 418
Query: 89 TSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKED 148
+LE+ NQ+L R + K R+S D + K L S ++ + L+ + ++
Sbjct: 419 MEAQLEEKNQELQRARQREKMNEEHNKRLS-DTVDKLLSESNERLQLHLKERMAALE--- 474
Query: 149 TEKERDLRDVGDWRKNIEE 167
+K LR+V +K +EE
Sbjct: 475 -DKNSLLREVESAKKQLEE 492
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 40.0 bits (92), Expect = 0.001
Identities = 36/139 (25%), Positives = 68/139 (48%), Gaps = 7/139 (5%)
Query: 31 EKEESRREAEKQNYLAEHC--PPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQK 88
+ E+ R+ +++ LAE L ++ EV+ Q A + AEE ++E R+++
Sbjct: 359 QTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQ 418
Query: 89 TSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKED 148
+LE+ NQ+L R + K R+S D + K L S ++ + L+ + ++
Sbjct: 419 MEAQLEEKNQELQRARQREKMNEEHNKRLS-DTVDKLLSESNERLQLHLKERMAALE--- 474
Query: 149 TEKERDLRDVGDWRKNIEE 167
+K LR+V +K +EE
Sbjct: 475 -DKNSLLREVESAKKQLEE 492
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 39.3 bits (90), Expect = 0.002
Identities = 41/192 (21%), Positives = 91/192 (47%), Gaps = 18/192 (9%)
Query: 3 DEEKRNRAITARRQHLKSVM---------LQIAATELEKEESRREAEKQNYLAEHCPPLH 53
DEE+ N +TA+++ L+ L++ ++EKE+ E + +N E
Sbjct: 928 DEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 987
Query: 54 IPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLR 113
I +++ ++ ++ H + A ++ E +V +K + Q++ DL G ++ +
Sbjct: 988 IIAKLTKEKKALQEAHQQ---ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQE--K 1042
Query: 114 RVRMSADAMLKALLGS---KHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSG 170
+VRM + + L G + MDL + +Q+ + +K+ +L + + R E+ G
Sbjct: 1043 KVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL-NARIEDEQALG 1101
Query: 171 MEGRKKMFESES 182
+ +KK+ E ++
Sbjct: 1102 SQLQKKLKELQA 1113
Score = 38.9 bits (89), Expect = 0.002
Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 24/175 (13%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
D+ K N AI RR +L L+ +E+ E R+ +Q + E
Sbjct: 1665 DDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELI--------------ETS 1710
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM 122
E + LH++ + +K M+ + + E+E+ Q+ + K K+ DA
Sbjct: 1711 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA-------ITDA- 1762
Query: 123 LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKM 177
A++ + K D A+L+++KK + +DL+ D + I K G + +K+
Sbjct: 1763 --AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKL 1815
Score = 31.2 bits (69), Expect = 0.51
Identities = 27/120 (22%), Positives = 57/120 (47%), Gaps = 13/120 (10%)
Query: 66 KQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKA 125
K+L K+ + +EK D++++VQ L D ++ L + ++ +A +K
Sbjct: 871 KELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC---------DQLIKNKIQLEAKVKE 921
Query: 126 L---LGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIE-EKSGMEGRKKMFESE 181
+ L + ++ +L A ++++ E +E +RD+ D+ +E EK E + K E
Sbjct: 922 MNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEE 981
Score = 28.1 bits (61), Expect = 4.4
Identities = 39/154 (25%), Positives = 75/154 (48%), Gaps = 31/154 (20%)
Query: 59 SEVQELCKQLHAKIDAAEEE---KYDMEVRVQKT----SKELEDMNQKLFDLRG------ 105
S++Q+ K+L A+I+ EEE + +V+K S+ELE+++++L + G
Sbjct: 1102 SQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQI 1161
Query: 106 ---KFKRPPLRRVRMS-ADAMLK-----ALLGSKHKVCM----DLRANLKQVK----KED 148
K + +++R +A L+ A L KH + + NL++VK KE
Sbjct: 1162 EMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEK 1221
Query: 149 TEKERDLRDV-GDWRKNIEEKSGMEGRKKMFESE 181
+E + +L DV + + I+ K+ +E + E +
Sbjct: 1222 SEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQ 1255
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 39.3 bits (90), Expect = 0.002
Identities = 42/195 (21%), Positives = 93/195 (47%), Gaps = 24/195 (12%)
Query: 3 DEEKRNRAITARRQHLKSVM---------LQIAATELEKEESRREAEKQNYLAEHCPPLH 53
DEE+ N +TA+++ L+ L++ ++EKE+ E + +N E
Sbjct: 932 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE------ 985
Query: 54 IPGSMSEVQELCKQLHAKIDAAEEEKYDM---EVRVQKTSKELEDMNQKLFDLRGKFKRP 110
+ G + +L K+ A +A ++ D+ E +V +K + Q++ DL G ++
Sbjct: 986 MAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQE 1045
Query: 111 PLRRVRMSADAMLKALLGS---KHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEE 167
+++RM + + L G + MD+ + +Q+ ++ +KE ++ + + E+
Sbjct: 1046 --KKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQS-KIEDEQ 1102
Query: 168 KSGMEGRKKMFESES 182
GM+ +KK+ E ++
Sbjct: 1103 ALGMQLQKKIKELQA 1117
Score = 34.7 bits (78), Expect = 0.046
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 14/111 (12%)
Query: 66 KQLHAKIDAAEEEKYDMEVRV-QKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLK 124
++ HA A E+ D RV QK KE +M ++ DL + +
Sbjct: 1197 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMET-------------VS 1243
Query: 125 ALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRK 175
G+ K+C L L ++K ++ E++R + D+ R ++ +SG R+
Sbjct: 1244 KAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQ 1294
Score = 34.7 bits (78), Expect = 0.046
Identities = 37/175 (21%), Positives = 73/175 (41%), Gaps = 24/175 (13%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
++ K A+ RR +L ++ LE+ E R+ +Q L +
Sbjct: 1669 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELL--------------DAS 1714
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM 122
E + LH + + K +E + + E+ED+ Q+ + K K+ DA
Sbjct: 1715 ERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA-------ITDA- 1766
Query: 123 LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKM 177
A++ + K D A+L+++KK + +DL+ D + + K G + +K+
Sbjct: 1767 --AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1819
Score = 33.1 bits (74), Expect = 0.14
Identities = 33/164 (20%), Positives = 71/164 (43%), Gaps = 25/164 (15%)
Query: 22 MLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYD 81
+L+ A TE E + E EK +++ + K+L K+ +EK D
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKE------------ELAKTEAKRKELEEKMVTLMQEKND 890
Query: 82 MEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKAL---LGSKHKVCMDLR 138
++++VQ + L D ++ L + ++ +A +K + + ++ +L
Sbjct: 891 LQLQVQAEADSLADAEERC---------DQLIKTKIQLEAKIKEVTERAEDEEEINAELT 941
Query: 139 ANLKQVKKEDTEKERDLRDVGDWRKNIE-EKSGMEGRKKMFESE 181
A ++++ E +E ++D+ D+ +E EK E + K E
Sbjct: 942 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 985
Score = 30.8 bits (68), Expect = 0.67
Identities = 33/163 (20%), Positives = 71/163 (43%), Gaps = 15/163 (9%)
Query: 4 EEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEH----CPPL-----HI 54
++K + + +H+++V + A+ E K+ + E E E C L +
Sbjct: 1394 KKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNF 1453
Query: 55 PGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRR 114
++E ++ C++ HA+++A+++E + + K E+ +L L KR
Sbjct: 1454 DKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETL----KRENKNL 1509
Query: 115 VRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRD 157
+ +D + G K +L KQV++E +E + L +
Sbjct: 1510 QQEISDLTEQIAEGGKR--IHELEKIKKQVEQEKSELQAALEE 1550
Score = 30.0 bits (66), Expect = 1.1
Identities = 36/165 (21%), Positives = 72/165 (43%), Gaps = 20/165 (12%)
Query: 29 ELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQK 88
+L+K+E + E + + + E+Q ++L +I+A + E +
Sbjct: 1083 KLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 89 TSKELEDMNQKLFDLRG---------KFKRPPLRRVRMS-ADAMLK-----ALLGSKHKV 133
S+ELE+++++L + G K + +++R +A L+ A L KH
Sbjct: 1143 LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHAD 1202
Query: 134 CM----DLRANLKQVK-KEDTEKERDLRDVGDWRKNIEEKSGMEG 173
+ + NL++VK K + EK ++ D N+E S +G
Sbjct: 1203 SVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKG 1247
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 39.3 bits (90), Expect = 0.002
Identities = 38/165 (23%), Positives = 78/165 (47%), Gaps = 7/165 (4%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHC--PPLHIPGSMSEVQ 62
++ + +I L++ + A + EE R+ +++ LAE + ++ EV+
Sbjct: 351 QRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVE 410
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM 122
Q A + AEE ++E R++ +LE+ NQ+L R + K R+S D +
Sbjct: 411 AELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLS-DTV 469
Query: 123 LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEE 167
+ L S ++ + L+ + ++ EK +++ +RKN+EE
Sbjct: 470 DRLLTESNERLQLHLKERMAALE----EKNVLIQESETFRKNLEE 510
Score = 30.0 bits (66), Expect = 1.1
Identities = 27/147 (18%), Positives = 65/147 (44%), Gaps = 3/147 (2%)
Query: 23 LQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDM 82
L+++ + E A Q +A +HI M+ + + H ++ E +
Sbjct: 195 LRVSLERVSALEEELAAANQEIVALREQNVHIQRKMASSEGSTESEH--LEGMEPGQKVH 252
Query: 83 EVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD-AMLKALLGSKHKVCMDLRANL 141
E R+ S + D ++ +L+ ++ +M A L + +G + R +L
Sbjct: 253 EKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDL 312
Query: 142 KQVKKEDTEKERDLRDVGDWRKNIEEK 168
+ ++ +T+ +RD+R+ ++++EE+
Sbjct: 313 IKTEEMNTKYQRDIREAMAQKEDMEER 339
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 38.9 bits (89), Expect = 0.002
Identities = 34/150 (22%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 31 EKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTS 90
EK + RR +K + P + +++ E K L K+D EEE+ ++K
Sbjct: 403 EKRKKRRGKKKVS-------PDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKRE 455
Query: 91 KELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKA-----LLGSKHKVCMDLRANLKQVK 145
K+L Q+ L K + + D + KA LL + + R +Q++
Sbjct: 456 KDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLR 515
Query: 146 KEDTEKERDLRDVGDWRKNIEEKSGMEGRK 175
+E EKE++ D+ + +++E++ + +K
Sbjct: 516 RELEEKEQERLDIEEKYTSLQEEAQGKTKK 545
Score = 31.2 bits (69), Expect = 0.51
Identities = 40/197 (20%), Positives = 83/197 (42%), Gaps = 41/197 (20%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKE------ESRREAEKQNYLAEHCPPLHIPGSM 58
EKR + + +Q +S++ +++A LEK+ + +AE+Q L E +
Sbjct: 452 EKREKDLLKAQQEHQSLLEKLSA--LEKKVIVGGVDLLAKAEEQEKLLEESNM-----EL 504
Query: 59 SEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMS 118
E ++ +QL +++ E+E+ D+E + +E + +KL + + M+
Sbjct: 505 EERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKL---------KKVWTMLMA 555
Query: 119 ADAMLKALLGSKHKVCMDLRANLKQVKKE--------DTEKERDLR-----------DVG 159
A + + L + L N++Q+ +E D RD + D+G
Sbjct: 556 AKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIG 615
Query: 160 DWRKNIEEKSGMEGRKK 176
+W+ +G RK+
Sbjct: 616 EWQLKCVAYTGNNMRKQ 632
>gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein 3
[Homo sapiens]
Length = 580
Score = 37.7 bits (86), Expect = 0.005
Identities = 35/175 (20%), Positives = 81/175 (46%), Gaps = 18/175 (10%)
Query: 5 EKRNRAITARRQH-------LKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGS 57
E++++ + R QH L+SV+ + AT+ +K +E+ +Q L H+ G
Sbjct: 160 EEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQFKESFQQVQLERDEYSEHLKGE 219
Query: 58 MSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRP-PLRRVR 116
+ Q+ +++ +I ++EK Q+ + +E + + L L+ + P P
Sbjct: 220 RARWQQRMRKMSQEICTLKKEK-------QQDMRRVEKLERSLSKLKNQMAEPLPPEPPA 272
Query: 117 MSADAMLKALLGSKHKVCMDLRANLK---QVKKEDTEKERDLRDVGDWRKNIEEK 168
+ ++ L+ L +V +L+A +K ++ + +E +R+ + + EE+
Sbjct: 273 VPSEVELQHLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQEERLRKQEER 327
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 37.4 bits (85), Expect = 0.007
Identities = 41/195 (21%), Positives = 93/195 (47%), Gaps = 24/195 (12%)
Query: 3 DEEKRNRAITARRQHLKSVM---------LQIAATELEKEESRREAEKQNYLAEHCPPLH 53
DEE+ N +TA+++ L+ L++ ++EKE+ E + +N E
Sbjct: 934 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE------ 987
Query: 54 IPGSMSEVQELCKQLHAKIDAAEEEKYDM---EVRVQKTSKELEDMNQKLFDLRGKFKRP 110
+ G + +L K+ A +A ++ D+ E +V +K + Q++ DL G ++
Sbjct: 988 MAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQE 1047
Query: 111 PLRRVRMSADAMLKALLGS---KHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEE 167
+++RM + + L G + MD+ +Q+ ++ +KE ++ ++ + E+
Sbjct: 1048 --KKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQS-KIEDEQ 1104
Query: 168 KSGMEGRKKMFESES 182
G++ +KK+ E ++
Sbjct: 1105 ALGIQLQKKIKELQA 1119
Score = 34.7 bits (78), Expect = 0.046
Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 15/118 (12%)
Query: 66 KQLHAKIDAAEEEKYDMEVRV-QKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLK 124
++ HA A E+ D RV QK KE +M ++ DL + + + K
Sbjct: 1199 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS------------NVETVSK 1246
Query: 125 ALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES 182
A G+ K+C L L ++K ++ E++R + D+ R ++ +SG E +++ E E+
Sbjct: 1247 AK-GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG-EFSRQLDEKEA 1302
Score = 34.7 bits (78), Expect = 0.046
Identities = 38/177 (21%), Positives = 74/177 (41%), Gaps = 28/177 (15%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
++ K A+ RR +L ++ LE+ E R+ +Q L +
Sbjct: 1671 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELL--------------DAS 1716
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM 122
E + LH + + K +E + + E+ED+ Q+ + K K+ DA
Sbjct: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA-------ITDA- 1768
Query: 123 LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE 179
A++ + K D A+L+++KK + +DL+ R + E+ ++G KK +
Sbjct: 1769 --AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ----LRLDEAEQLALKGGKKQIQ 1819
Score = 32.0 bits (71), Expect = 0.30
Identities = 33/164 (20%), Positives = 73/164 (44%), Gaps = 25/164 (15%)
Query: 22 MLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYD 81
+L+ A TE E + E +K I +++ + K+L K+ +EK D
Sbjct: 845 LLKSAETEKEMATMKEEFQK------------IKDELAKSEAKRKELEEKMVTLLKEKND 892
Query: 82 MEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKAL---LGSKHKVCMDLR 138
++++VQ ++ L D ++ L + ++ +A +K + + ++ +L
Sbjct: 893 LQLQVQAEAEGLADAEERC---------DQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943
Query: 139 ANLKQVKKEDTEKERDLRDVGDWRKNIE-EKSGMEGRKKMFESE 181
A ++++ E +E ++D+ D+ +E EK E + K E
Sbjct: 944 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 987
Score = 31.2 bits (69), Expect = 0.51
Identities = 23/114 (20%), Positives = 54/114 (47%), Gaps = 9/114 (7%)
Query: 4 EEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEH----CPPL-----HI 54
++K + + A +H+++V + A+ E K+ + E E E C L +
Sbjct: 1396 KKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF 1455
Query: 55 PGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFK 108
++E ++ C++ HA+++A+++E + + K E+ +L L+ + K
Sbjct: 1456 DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENK 1509
Score = 30.4 bits (67), Expect = 0.88
Identities = 37/169 (21%), Positives = 76/169 (44%), Gaps = 24/169 (14%)
Query: 29 ELEKEESRREAEKQNYLA----EHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEV 84
+L+++ ++E E N + E + + + E+Q ++L +I+A + E
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 85 RVQKTSKELEDMNQKLFDLRG---------KFKRPPLRRVRMS-ADAMLK-----ALLGS 129
+ S+ELE+++++L + G K + +++R +A L+ A L
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
Query: 130 KHKVCM----DLRANLKQVK-KEDTEKERDLRDVGDWRKNIEEKSGMEG 173
KH + + NL++VK K + EK ++ D N+E S +G
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 37.4 bits (85), Expect = 0.007
Identities = 41/195 (21%), Positives = 93/195 (47%), Gaps = 24/195 (12%)
Query: 3 DEEKRNRAITARRQHLKSVM---------LQIAATELEKEESRREAEKQNYLAEHCPPLH 53
DEE+ N +TA+++ L+ L++ ++EKE+ E + +N E
Sbjct: 934 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE------ 987
Query: 54 IPGSMSEVQELCKQLHAKIDAAEEEKYDM---EVRVQKTSKELEDMNQKLFDLRGKFKRP 110
+ G + +L K+ A +A ++ D+ E +V +K + Q++ DL G ++
Sbjct: 988 MAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQE 1047
Query: 111 PLRRVRMSADAMLKALLGS---KHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEE 167
+++RM + + L G + MD+ +Q+ ++ +KE ++ ++ + E+
Sbjct: 1048 --KKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQS-KIEDEQ 1104
Query: 168 KSGMEGRKKMFESES 182
G++ +KK+ E ++
Sbjct: 1105 ALGIQLQKKIKELQA 1119
Score = 34.7 bits (78), Expect = 0.046
Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 15/118 (12%)
Query: 66 KQLHAKIDAAEEEKYDMEVRV-QKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLK 124
++ HA A E+ D RV QK KE +M ++ DL + + + K
Sbjct: 1199 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS------------NVETVSK 1246
Query: 125 ALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES 182
A G+ K+C L L ++K ++ E++R + D+ R ++ +SG E +++ E E+
Sbjct: 1247 AK-GNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG-EFSRQLDEKEA 1302
Score = 34.7 bits (78), Expect = 0.046
Identities = 38/177 (21%), Positives = 74/177 (41%), Gaps = 28/177 (15%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
++ K A+ RR +L ++ LE+ E R+ +Q L +
Sbjct: 1671 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELL--------------DAS 1716
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM 122
E + LH + + K +E + + E+ED+ Q+ + K K+ DA
Sbjct: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA-------ITDA- 1768
Query: 123 LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFE 179
A++ + K D A+L+++KK + +DL+ R + E+ ++G KK +
Sbjct: 1769 --AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ----LRLDEAEQLALKGGKKQIQ 1819
Score = 32.0 bits (71), Expect = 0.30
Identities = 33/164 (20%), Positives = 73/164 (44%), Gaps = 25/164 (15%)
Query: 22 MLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYD 81
+L+ A TE E + E +K I +++ + K+L K+ +EK D
Sbjct: 845 LLKSAETEKEMATMKEEFQK------------IKDELAKSEAKRKELEEKMVTLLKEKND 892
Query: 82 MEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKAL---LGSKHKVCMDLR 138
++++VQ ++ L D ++ L + ++ +A +K + + ++ +L
Sbjct: 893 LQLQVQAEAEGLADAEERC---------DQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943
Query: 139 ANLKQVKKEDTEKERDLRDVGDWRKNIE-EKSGMEGRKKMFESE 181
A ++++ E +E ++D+ D+ +E EK E + K E
Sbjct: 944 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 987
Score = 31.2 bits (69), Expect = 0.51
Identities = 23/114 (20%), Positives = 54/114 (47%), Gaps = 9/114 (7%)
Query: 4 EEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEH----CPPL-----HI 54
++K + + A +H+++V + A+ E K+ + E E E C L +
Sbjct: 1396 KKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNF 1455
Query: 55 PGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFK 108
++E ++ C++ HA+++A+++E + + K E+ +L L+ + K
Sbjct: 1456 DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENK 1509
Score = 30.4 bits (67), Expect = 0.88
Identities = 37/169 (21%), Positives = 76/169 (44%), Gaps = 24/169 (14%)
Query: 29 ELEKEESRREAEKQNYLA----EHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEV 84
+L+++ ++E E N + E + + + E+Q ++L +I+A + E
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 85 RVQKTSKELEDMNQKLFDLRG---------KFKRPPLRRVRMS-ADAMLK-----ALLGS 129
+ S+ELE+++++L + G K + +++R +A L+ A L
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
Query: 130 KHKVCM----DLRANLKQVK-KEDTEKERDLRDVGDWRKNIEEKSGMEG 173
KH + + NL++VK K + EK ++ D N+E S +G
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 37.4 bits (85), Expect = 0.007
Identities = 42/185 (22%), Positives = 76/185 (41%), Gaps = 30/185 (16%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
D+ K A+ RR +L ++ LE+ E R+ +Q L +
Sbjct: 1669 DDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL--------------DAS 1714
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM 122
E + LH + + K +E + + E+ED+ Q+ + K K+ DA
Sbjct: 1715 ERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKA-------ITDA- 1766
Query: 123 LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSG------MEGRKK 176
A++ + K D A+L+++KK + +DL+ D + + K G +E R +
Sbjct: 1767 --AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVR 1824
Query: 177 MFESE 181
ESE
Sbjct: 1825 ELESE 1829
Score = 35.8 bits (81), Expect = 0.021
Identities = 41/192 (21%), Positives = 81/192 (42%), Gaps = 46/192 (23%)
Query: 3 DEEKRNRAITARRQHLKSVM---------LQIAATELEKEESRREAEKQNYLAEHCPPLH 53
DEE+ N +TA+++ L+ L++ ++EKE+ E + +N E
Sbjct: 932 DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE------ 985
Query: 54 IPGSMSEVQELCKQLHAKIDAAEEEKYDMEV---RVQKTSKELEDMNQKLFDLRGKFKRP 110
+ G + +L K+ A +A ++ D+++ +V +K + Q++ DL G
Sbjct: 986 MAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGS---- 1041
Query: 111 PLRRVRMSADAMLKALLGSKHKVCMD-------LRANLKQVKKEDTEKERDLRDVGDWRK 163
L + K+CMD L +LK ++ + E D + + + K
Sbjct: 1042 ----------------LEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLK 1085
Query: 164 NIE-EKSGMEGR 174
E E S ++G+
Sbjct: 1086 KKEFEMSNLQGK 1097
Score = 32.7 bits (73), Expect = 0.18
Identities = 33/164 (20%), Positives = 71/164 (43%), Gaps = 25/164 (15%)
Query: 22 MLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYD 81
+L+ A TE E + E EK +++ + K+L K+ +EK D
Sbjct: 843 LLKSAETEKEMANMKEEFEKTKE------------ELAKTEAKRKELEEKMVTLMQEKND 890
Query: 82 MEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKAL---LGSKHKVCMDLR 138
++++VQ + L D ++ L + ++ +A +K + + ++ +L
Sbjct: 891 LQLQVQAEADALADAEERC---------DQLIKTKIQLEAKIKEVTERAEDEEEINAELT 941
Query: 139 ANLKQVKKEDTEKERDLRDVGDWRKNIE-EKSGMEGRKKMFESE 181
A ++++ E +E ++D+ D+ +E EK E + K E
Sbjct: 942 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 985
Score = 31.6 bits (70), Expect = 0.39
Identities = 29/151 (19%), Positives = 70/151 (46%), Gaps = 16/151 (10%)
Query: 33 EESRREAEKQNYLAEHCPPLH-----IPGSMSEVQELC-------KQLHAKIDAAEEEKY 80
++ + E +K N L + L + GS+ + ++LC ++L + A+E
Sbjct: 1012 DDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTM 1071
Query: 81 DMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM-LKALLGSKHKVCMDLRA 139
D E Q+ +++L+ ++ +L+GK + +++ L+A + + RA
Sbjct: 1072 DTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERA 1131
Query: 140 NLKQVKKEDTEKERDLRDVGDWRKNIEEKSG 170
+ + +K+ ++ R+L ++ + +EE G
Sbjct: 1132 SRAKAEKQRSDLSRELEEISE---RLEEAGG 1159
Score = 29.3 bits (64), Expect = 2.0
Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 14/111 (12%)
Query: 66 KQLHAKIDAAEEEKYDMEVRV-QKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLK 124
++ HA A E+ D RV QK KE ++ ++ DL M + K
Sbjct: 1197 RKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASN----------METVSKAK 1246
Query: 125 ALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRK 175
A + K+C L L ++K ++ E++R + ++ + + +SG R+
Sbjct: 1247 A---NFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQ 1294
Score = 27.7 bits (60), Expect = 5.7
Identities = 17/81 (20%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Query: 29 ELEKEESRREAEKQNYLA----EHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEV 84
+L ++ ++E E N E + + + E+Q ++L +I+A + E
Sbjct: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1138
Query: 85 RVQKTSKELEDMNQKLFDLRG 105
+ S+ELE+++++L + G
Sbjct: 1139 QRSDLSRELEEISERLEEAGG 1159
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 37.4 bits (85), Expect = 0.007
Identities = 38/190 (20%), Positives = 82/190 (43%), Gaps = 26/190 (13%)
Query: 1 MGDEEKRNRAITARRQHL---------KSVMLQIAATELEKEESRREAEKQNYLAEHCPP 51
+ DE ++ +A ++ L K M + A E E+E RRE EK+
Sbjct: 318 INDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEI-------- 369
Query: 52 LHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPP 111
+ +QE + A+ DA ++ + EV ++ ++ ++ +K + + ++
Sbjct: 370 ----ARLRAMQEKAQDYQAEQDALRAKR-NQEVADREWRRKEKENARKKMETEAELRKSR 424
Query: 112 LRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERD----LRDVGDWRKNIEE 167
L +V A+ + + + LRA +Q++KE E+E+ L+ + R+ + E
Sbjct: 425 LEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRE 484
Query: 168 KSGMEGRKKM 177
E + ++
Sbjct: 485 NQQKEVQNRI 494
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 36.6 bits (83), Expect = 0.012
Identities = 31/156 (19%), Positives = 71/156 (45%), Gaps = 16/156 (10%)
Query: 29 ELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEEEKYDMEVRVQK 88
++ +EE RE EK+ E M E +E ++ K+ EE+ ++ E ++Q+
Sbjct: 584 KMREEERMREREKKMREEEEM--------MREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635
Query: 89 TSKELEDMNQKLFDLRGKF---KRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVK 145
+++ + +K+++ K +R P ++ ++ ++ + + + + + +
Sbjct: 636 QEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ-----EQEKMQEQEEKIWEQE 690
Query: 146 KEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESE 181
K + + + + D K EE+S E KKM E E
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Score = 34.3 bits (77), Expect = 0.061
Identities = 43/181 (23%), Positives = 76/181 (41%), Gaps = 12/181 (6%)
Query: 1 MGDEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSE 60
M +E+R R + + + M + E+E+ RE EK+ L E M E
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE--LREQKELREQEEQMQE 352
Query: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD 120
+E + K+ EE+ + E R+ + K++ + QK+ D + R+R +
Sbjct: 353 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD-ERLREKEE 411
Query: 121 AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFES 180
M + + M + + +K+ E+E+ RD + K EE+ E KKM E
Sbjct: 412 RM-------REQEKMWEQVEKMREEKKMQEQEKKTRDQEE--KMQEEERIREREKKMREE 462
Query: 181 E 181
E
Sbjct: 463 E 463
Score = 33.5 bits (75), Expect = 0.10
Identities = 39/190 (20%), Positives = 76/190 (40%), Gaps = 49/190 (25%)
Query: 11 ITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHA 70
+T R L + + T E ++ E +++ LAE SE+Q K+L
Sbjct: 202 LTKERDALSLELYRNTITNEELKKKNAELQEKLPLAE--------SEKSEIQLNVKELKR 253
Query: 71 KIDAA-------------------EEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPP 111
K++ A EEE + E +++K +++ ++L + GK +
Sbjct: 254 KLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE 313
Query: 112 LRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGM 171
+ R L++ +KE E+E++LR+ + R+ +E+
Sbjct: 314 EKMWRQ--------------------EKRLREQEKELREQEKELREQKELRE--QEEQMQ 351
Query: 172 EGRKKMFESE 181
E +KM+E E
Sbjct: 352 EQEEKMWEQE 361
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 36.6 bits (83), Expect = 0.012
Identities = 40/176 (22%), Positives = 80/176 (45%), Gaps = 28/176 (15%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQEL 64
E++N+ + A + L S + E E+S+R E+Q + E++
Sbjct: 1503 ERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQ---------------VEEMRTQ 1547
Query: 65 CKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVR-----MSA 119
++L ++ A E+ K +EV +Q + E Q + + KR +++VR +
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED 1607
Query: 120 DAMLKAL-LGSKHKVCMDLR---ANLKQVKKEDTEKERDLR----DVGDWRKNIEE 167
+ +AL + SK K+ +DL+ A ++ K E + LR + D+++ +EE
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEE 1663
Score = 32.0 bits (71), Expect = 0.30
Identities = 37/166 (22%), Positives = 75/166 (45%), Gaps = 25/166 (15%)
Query: 6 KRNRAITARRQHLKSVMLQIAATELEKEESRRE----AEKQNYLAEHCPPLHIPGSMSEV 61
++ + A+ + L V + E E EE R+ E++N LAE +E
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAE--TELFAEA 906
Query: 62 QELCKQLHAKIDAAEEEKYDMEVRVQ--------------KTSKELEDMNQKLFDLRGKF 107
+E+ +L AK EE +D+E RV+ K ++D+ ++L + G
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG-- 964
Query: 108 KRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKER 153
R L+ +++A+A +K + + ++ + N K +K++ ++R
Sbjct: 965 ARQKLQLEKVTAEAKIKKM---EEEILLLEDQNSKFIKEKKLMEDR 1007
Score = 31.2 bits (69), Expect = 0.51
Identities = 20/106 (18%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 66 KQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAML-- 123
++LHAK+ + + ++ + K EL++++ L + K + + S ++ L
Sbjct: 1262 QELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK--FAKDAASLESQLQD 1319
Query: 124 -KALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEK 168
+ LL + + ++L + ++Q+++E + + + RKN+E++
Sbjct: 1320 TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365
Score = 30.4 bits (67), Expect = 0.88
Identities = 46/195 (23%), Positives = 79/195 (40%), Gaps = 27/195 (13%)
Query: 5 EKRNRAITARRQHLKSVMLQIAAT--ELEKEESRREAEKQNYLAE-HCPPLHIPGSMSEV 61
EK R + L+ + ++ A EL+ + +++E E Q LA LH ++ V
Sbjct: 1054 EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV 1113
Query: 62 QELCKQL----------HAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPP 111
+EL Q+ A + AE++K D+ ++ ELED L +
Sbjct: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED------TLDTTAAQQE 1167
Query: 112 LRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDT----EKERDLRDVGDWRKNIEE 167
LR R A LK L + K + A ++ +++ E L ++ N+E+
Sbjct: 1168 LRTKREQEVAELKKALEEETK---NHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEK 1224
Query: 168 -KSGMEGRKKMFESE 181
K G+E K E
Sbjct: 1225 NKQGLETDNKELACE 1239
Score = 28.1 bits (61), Expect = 4.4
Identities = 32/166 (19%), Positives = 76/166 (45%), Gaps = 19/166 (11%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
+EE+RN+ + ++ +++ + + E+E +R++ + + AE + +++
Sbjct: 933 EEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE--------AKIKKME 984
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAM 122
E L + +EK ME R+ + S +L + +K + L ++R + M
Sbjct: 985 EEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKN---------LAKIRNKQEVM 1035
Query: 123 LKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRD-VGDWRKNIEE 167
+ L + K R L++ K++ + DL+D + + + I+E
Sbjct: 1036 ISD-LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
Score = 28.1 bits (61), Expect = 4.4
Identities = 28/138 (20%), Positives = 58/138 (42%), Gaps = 18/138 (13%)
Query: 18 LKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQLHAKIDAAEE 77
L++ +LQ+ E +RR AE++ E+ + + A +
Sbjct: 1685 LEAEILQLQEELASSERARRHAEQER---------------DELADEITNSASGKSALLD 1729
Query: 78 EKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDL 137
EK +E R+ + +ELE+ + L +F++ L+ ++A+ + K +
Sbjct: 1730 EKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSD---NA 1786
Query: 138 RANLKQVKKEDTEKERDL 155
R L++ KE K ++L
Sbjct: 1787 RQQLERQNKELKAKLQEL 1804
Score = 28.1 bits (61), Expect = 4.4
Identities = 20/91 (21%), Positives = 37/91 (40%), Gaps = 19/91 (20%)
Query: 8 NRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQ 67
N+ + + LK + +Q+ E+ RR A++ M + KQ
Sbjct: 1841 NKLVRRTEKKLKEIFMQV-------EDERRHADQYKE------------QMEKANARMKQ 1881
Query: 68 LHAKIDAAEEEKYDMEVRVQKTSKELEDMNQ 98
L +++ AEEE +K +EL+D +
Sbjct: 1882 LKRQLEEAEEEATRANASRRKLQRELDDATE 1912
Score = 27.3 bits (59), Expect = 7.4
Identities = 23/107 (21%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEK-----QNYLAEHCPPLHIP-G 56
+E ++ +++R + L+ + + E+EE+R+ EK Q+ LA+ + G
Sbjct: 1326 EETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLG 1385
Query: 57 SMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDL 103
++ ++E K+L +A + + + K K + Q+L DL
Sbjct: 1386 TIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDL 1432
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 36.6 bits (83), Expect = 0.012
Identities = 35/145 (24%), Positives = 68/145 (46%), Gaps = 17/145 (11%)
Query: 15 RQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQELCKQ---LHAK 71
++ L + Q++ E E E++RREA++Q E + E + L K+ L +
Sbjct: 833 QEQLAQLSRQLSGREQELEQARREAQRQVEALER--------AAREKEALAKEHAGLAVQ 884
Query: 72 IDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKH 131
+ AAE E + + E E + LF+++ + + RR ++ A+ +ALL +K
Sbjct: 885 LVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEG--QALLLAKE 942
Query: 132 KVCMDLRANLKQV----KKEDTEKE 152
+ +L +Q+ +K +KE
Sbjct: 943 TLTGELAGLRQQIIATQEKASLDKE 967
Score = 33.1 bits (74), Expect = 0.14
Identities = 35/181 (19%), Positives = 77/181 (42%), Gaps = 12/181 (6%)
Query: 6 KRNRAITARRQHLKSVMLQIAATELEKEESRREAEK---QNYLAEHCPPLHIPGSMSEVQ 62
+R A A Q ++ + Q +++ REAE+ Q L E + + E Q
Sbjct: 1123 QREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARD-GLRRELLEAQ 1181
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSAD-- 120
++ + +E ++ + + +KE E + + +LR K+ R+ +
Sbjct: 1182 RKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANE 1241
Query: 121 ------AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGR 174
A+L+ + K +LR L++V++ E R+L+++ K ++ ++ GR
Sbjct: 1242 DKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGR 1301
Query: 175 K 175
+
Sbjct: 1302 E 1302
Score = 32.3 bits (72), Expect = 0.23
Identities = 41/208 (19%), Positives = 80/208 (38%), Gaps = 32/208 (15%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQEL 64
+K + A+ A + V +A EL E A + L ++Q
Sbjct: 575 DKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELR--QEREKLQAA 632
Query: 65 CKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGK--------------FKRP 110
++L + D EEE+ D + +ELE +++L L GK R
Sbjct: 633 QEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRA 692
Query: 111 PLRRVRMSAD-AMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNI---- 165
L+R + A+ A + L ++L ++ +++ E+ + L + +++
Sbjct: 693 TLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDK 752
Query: 166 -----------EEKSGMEGRKKMFESES 182
EEKS ++GR++ E E+
Sbjct: 753 LDLNRLVAQLEEEKSALQGRQRQAEQEA 780
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 36.2 bits (82), Expect = 0.016
Identities = 30/114 (26%), Positives = 54/114 (47%), Gaps = 8/114 (7%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQN-YLAEHCPPLHIPG-SMSE 60
++E R + + H + + A TE + + + E EK+ LAE L I + +
Sbjct: 169 EDEARKKKALSNMMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQ 228
Query: 61 VQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDM------NQKLFDLRGKFK 108
++E K+L I E EK+D++ + ++ E+ + NQK+ RGK K
Sbjct: 229 LREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAK 282
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 36.2 bits (82), Expect = 0.016
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 31/122 (25%)
Query: 3 DEEKRNRAITAR-----RQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGS 57
++E R R ++ + + LK V+LQ+ ++ R + EK N
Sbjct: 1856 EQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRV----------- 1904
Query: 58 MSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELED-------MNQKLFDLRGKFKRP 110
KQL +++ AEEE + ++ +ELED MN+++ LR + +R
Sbjct: 1905 --------KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1956
Query: 111 PL 112
PL
Sbjct: 1957 PL 1958
Score = 35.0 bits (79), Expect = 0.036
Identities = 46/185 (24%), Positives = 89/185 (48%), Gaps = 23/185 (12%)
Query: 4 EEKRNRAITARRQHLKSVMLQIAATELEKEE-SRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
EE R R + AR+Q L+ V+ ++ A E+EE SR+ ++ L +H +Q
Sbjct: 932 EETRGR-LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH------------IQ 978
Query: 63 ELCKQLHAKIDAAEE---EKYDMEVRVQKTSKE---LEDMNQKLFDLRGKFKRPPLRRVR 116
EL L A+ A ++ EK E +++K ++ LED N KL R K L
Sbjct: 979 ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKER-KLLEDRLAEFS 1037
Query: 117 MSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKK 176
A A + + S +K+ + A + ++ ++E+ +++ ++ ++ +S E +++
Sbjct: 1038 SQA-AEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS-ELQEQ 1095
Query: 177 MFESE 181
M E +
Sbjct: 1096 MVEQQ 1100
Score = 34.3 bits (77), Expect = 0.061
Identities = 43/174 (24%), Positives = 71/174 (40%), Gaps = 18/174 (10%)
Query: 5 EKRNRAITARRQHLKSVML--QIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
EK R + L+ M+ Q A EL + R+E E Q LA G+ +++
Sbjct: 1079 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDE---GGARAQLL 1135
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFK--------RPPLRR 114
+ ++ A + A+E+ V K K+ D+ ++L LRG+ + + LR
Sbjct: 1136 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS 1195
Query: 115 VRMSADAMLKALLGSKHKV----CMDLRANLKQVKKEDTEK-ERDLRDVGDWRK 163
R LK L + ++ +LR Q E E+ E+ R G W K
Sbjct: 1196 KREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1249
Score = 30.4 bits (67), Expect = 0.88
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 41/203 (20%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNY-LAEHCPPL-----HIPGSM 58
E+R RA R+ + A E E++E+R E E+QN L L + S+
Sbjct: 1494 EERERAEAEGREREARALSLTRALE-EEQEAREELERQNRALRAELEALLSSKDDVGKSV 1552
Query: 59 SEVQELCK--------------QLHAKIDAAEEEKYDMEVRVQ--KTSKEL--------- 93
E++ C+ +L ++ AAE+ K +EV VQ KT E
Sbjct: 1553 HELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAG 1612
Query: 94 -EDMNQKLFDLR-GKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRA-------NLKQV 144
E Q LR + +R R+ R A A K L G ++ + + +KQ+
Sbjct: 1613 EERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQL 1672
Query: 145 KKEDTEKERDLRDVGDWRKNIEE 167
+K + + R+V + R + EE
Sbjct: 1673 RKMQAQMKELWREVEETRTSREE 1695
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 36.2 bits (82), Expect = 0.016
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 31/122 (25%)
Query: 3 DEEKRNRAITAR-----RQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGS 57
++E R R ++ + + LK V+LQ+ ++ R + EK N
Sbjct: 1848 EQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRV----------- 1896
Query: 58 MSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELED-------MNQKLFDLRGKFKRP 110
KQL +++ AEEE + ++ +ELED MN+++ LR + +R
Sbjct: 1897 --------KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1948
Query: 111 PL 112
PL
Sbjct: 1949 PL 1950
Score = 35.0 bits (79), Expect = 0.036
Identities = 46/185 (24%), Positives = 89/185 (48%), Gaps = 23/185 (12%)
Query: 4 EEKRNRAITARRQHLKSVMLQIAATELEKEE-SRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
EE R R + AR+Q L+ V+ ++ A E+EE SR+ ++ L +H +Q
Sbjct: 924 EETRGR-LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH------------IQ 970
Query: 63 ELCKQLHAKIDAAEE---EKYDMEVRVQKTSKE---LEDMNQKLFDLRGKFKRPPLRRVR 116
EL L A+ A ++ EK E +++K ++ LED N KL R K L
Sbjct: 971 ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKER-KLLEDRLAEFS 1029
Query: 117 MSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKK 176
A A + + S +K+ + A + ++ ++E+ +++ ++ ++ +S E +++
Sbjct: 1030 SQA-AEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS-ELQEQ 1087
Query: 177 MFESE 181
M E +
Sbjct: 1088 MVEQQ 1092
Score = 34.3 bits (77), Expect = 0.061
Identities = 43/174 (24%), Positives = 71/174 (40%), Gaps = 18/174 (10%)
Query: 5 EKRNRAITARRQHLKSVML--QIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
EK R + L+ M+ Q A EL + R+E E Q LA G+ +++
Sbjct: 1071 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDE---GGARAQLL 1127
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFK--------RPPLRR 114
+ ++ A + A+E+ V K K+ D+ ++L LRG+ + + LR
Sbjct: 1128 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS 1187
Query: 115 VRMSADAMLKALLGSKHKV----CMDLRANLKQVKKEDTEK-ERDLRDVGDWRK 163
R LK L + ++ +LR Q E E+ E+ R G W K
Sbjct: 1188 KREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1241
Score = 30.4 bits (67), Expect = 0.88
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 41/203 (20%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNY-LAEHCPPL-----HIPGSM 58
E+R RA R+ + A E E++E+R E E+QN L L + S+
Sbjct: 1486 EERERAEAEGREREARALSLTRALE-EEQEAREELERQNRALRAELEALLSSKDDVGKSV 1544
Query: 59 SEVQELCK--------------QLHAKIDAAEEEKYDMEVRVQ--KTSKEL--------- 93
E++ C+ +L ++ AAE+ K +EV VQ KT E
Sbjct: 1545 HELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAG 1604
Query: 94 -EDMNQKLFDLR-GKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRA-------NLKQV 144
E Q LR + +R R+ R A A K L G ++ + + +KQ+
Sbjct: 1605 EERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQL 1664
Query: 145 KKEDTEKERDLRDVGDWRKNIEE 167
+K + + R+V + R + EE
Sbjct: 1665 RKMQAQMKELWREVEETRTSREE 1687
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 36.2 bits (82), Expect = 0.016
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 31/122 (25%)
Query: 3 DEEKRNRAITAR-----RQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGS 57
++E R R ++ + + LK V+LQ+ ++ R + EK N
Sbjct: 1889 EQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRV----------- 1937
Query: 58 MSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELED-------MNQKLFDLRGKFKRP 110
KQL +++ AEEE + ++ +ELED MN+++ LR + +R
Sbjct: 1938 --------KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1989
Query: 111 PL 112
PL
Sbjct: 1990 PL 1991
Score = 35.0 bits (79), Expect = 0.036
Identities = 46/185 (24%), Positives = 89/185 (48%), Gaps = 23/185 (12%)
Query: 4 EEKRNRAITARRQHLKSVMLQIAATELEKEE-SRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
EE R R + AR+Q L+ V+ ++ A E+EE SR+ ++ L +H +Q
Sbjct: 965 EETRGR-LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH------------IQ 1011
Query: 63 ELCKQLHAKIDAAEE---EKYDMEVRVQKTSKE---LEDMNQKLFDLRGKFKRPPLRRVR 116
EL L A+ A ++ EK E +++K ++ LED N KL R K L
Sbjct: 1012 ELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKER-KLLEDRLAEFS 1070
Query: 117 MSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKK 176
A A + + S +K+ + A + ++ ++E+ +++ ++ ++ +S E +++
Sbjct: 1071 SQA-AEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS-ELQEQ 1128
Query: 177 MFESE 181
M E +
Sbjct: 1129 MVEQQ 1133
Score = 34.3 bits (77), Expect = 0.061
Identities = 43/174 (24%), Positives = 71/174 (40%), Gaps = 18/174 (10%)
Query: 5 EKRNRAITARRQHLKSVML--QIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
EK R + L+ M+ Q A EL + R+E E Q LA G+ +++
Sbjct: 1112 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDE---GGARAQLL 1168
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFK--------RPPLRR 114
+ ++ A + A+E+ V K K+ D+ ++L LRG+ + + LR
Sbjct: 1169 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS 1228
Query: 115 VRMSADAMLKALLGSKHKV----CMDLRANLKQVKKEDTEK-ERDLRDVGDWRK 163
R LK L + ++ +LR Q E E+ E+ R G W K
Sbjct: 1229 KREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1282
Score = 30.4 bits (67), Expect = 0.88
Identities = 51/203 (25%), Positives = 83/203 (40%), Gaps = 41/203 (20%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNY-LAEHCPPL-----HIPGSM 58
E+R RA R+ + A E E++E+R E E+QN L L + S+
Sbjct: 1527 EERERAEAEGREREARALSLTRALE-EEQEAREELERQNRALRAELEALLSSKDDVGKSV 1585
Query: 59 SEVQELCK--------------QLHAKIDAAEEEKYDMEVRVQ--KTSKEL--------- 93
E++ C+ +L ++ AAE+ K +EV VQ KT E
Sbjct: 1586 HELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAG 1645
Query: 94 -EDMNQKLFDLR-GKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRA-------NLKQV 144
E Q LR + +R R+ R A A K L G ++ + + +KQ+
Sbjct: 1646 EERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQL 1705
Query: 145 KKEDTEKERDLRDVGDWRKNIEE 167
+K + + R+V + R + EE
Sbjct: 1706 RKMQAQMKELWREVEETRTSREE 1728
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 36.2 bits (82), Expect = 0.016
Identities = 37/187 (19%), Positives = 83/187 (44%), Gaps = 25/187 (13%)
Query: 3 DEEKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQ 62
DEE+R R + + + + E EK++ + ++++ + H G E
Sbjct: 565 DEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEA- 623
Query: 63 ELCKQLHAKIDAAEEEKYDMEVRV--------------------QKTSKELEDMNQKLFD 102
E+ KQL ++ A+E + +M++ + +K+ ELED+ Q+L D
Sbjct: 624 EIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKD 683
Query: 103 LRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWR 162
L K K+ +M+ + L+ + + ++ L+ L K+E+ ++ G
Sbjct: 684 LEDKEKK---ENKKMADEDALRKIRAVEEQI-EYLQKKLAMAKQEEEALLSEMDVTGQAF 739
Query: 163 KNIEEKS 169
++++E++
Sbjct: 740 EDMQEQN 746
>gi|238908495 similar to pleckstrin homology domain protein (5V327)
[Homo sapiens]
Length = 506
Score = 35.8 bits (81), Expect = 0.021
Identities = 33/178 (18%), Positives = 76/178 (42%), Gaps = 35/178 (19%)
Query: 5 EKRNRAITARRQHLKSVMLQIAATELEKEESRREAEKQNYLAEHCPPLHIPGSMSEVQEL 64
E+ N+ + A +Q + V+ ++ +E+E+ +RE E L C + V++
Sbjct: 188 ERLNQVLEAEKQQFEEVVQEL---RMEQEQIKRELE----LTARC--------LKGVEQE 232
Query: 65 CKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLK 124
K+L ++ ++ ++ + +KT + LE+ L L + ++PP
Sbjct: 233 KKELRHLTESLQQTLEELSIEKKKTLEMLEENENHLQTLANQSEQPPPS----------- 281
Query: 125 ALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES 182
G H + ++Q+ +E E+ +++ N E +E ++ + S+S
Sbjct: 282 ---GGLHSNLRQIEEKMQQLLEEKLLAEKRMKE------NEERSRALEEEREFYSSQS 330
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,669,288
Number of Sequences: 37866
Number of extensions: 278193
Number of successful extensions: 2164
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 276
Number of HSP's that attempted gapping in prelim test: 1669
Number of HSP's gapped (non-prelim): 730
length of query: 182
length of database: 18,247,518
effective HSP length: 96
effective length of query: 86
effective length of database: 14,612,382
effective search space: 1256664852
effective search space used: 1256664852
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.