Guide to the Human Genome
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Name: SH2B1 Sequence: fasta or formatted (671aa) NCBI GI: 224926822
Description:

SH2B adaptor protein 1 isoform 2

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt mRNA [671aa] SH2B adaptor protein 1 isoform 2
alt prot [756aa] SH2B adaptor protein 1 isoform 1
alt mRNA [671aa] SH2B adaptor protein 1 isoform 2
alt prot [683aa] SH2B adaptor protein 1 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         49           3
 C cysteine            1.8         12           1
 D aspartate           3.7         25           1
 E glutamate           6.9         46           2
 F phenylalanine       3.7         25           2
 G glycine            11.5         77           4
 H histidine           2.7         18           1
 I isoleucine          1.9         13           1
 K lysine              1.8         12           2
 L leucine            10.0         67           3
 M methionine          1.5         10           1
 N asparagine          1.5         10           1
 P proline            10.7         72           6
 Q glutamine           3.4         23           2
 R arginine            6.7         45           2
 S serine             13.1         88           4
 T threonine           4.3         29           3
 V valine              5.2         35           2
 W tryptophan          1.0          7           1
 Y tyrosine            1.2          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SH2B adaptor protein 1 isoform 2 
SH2B1                 1.000   SH2B adaptor protein 1 isoform 2 
SH2B1                 1.000   SH2B adaptor protein 1 isoform 2 
SH2B1                 0.941   SH2B adaptor protein 1 isoform 3 
SH2B1                 0.936   SH2B adaptor protein 1 isoform 1 
SH2B2                 0.255   SH2B adaptor protein 2 
SH2B3                 0.099   SH2B adaptor protein 3 
SHC1                  0.028   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.028   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.028   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.028   SHC (Src homology 2 domain containing) transforming ...
CSK                   0.024   c-src tyrosine kinase 
CSK                   0.024   c-src tyrosine kinase 
LOC100291393          0.024   PREDICTED: hypothetical protein XP_002347924 
SHC2                  0.024   SHC (Src homology 2 domain containing) transforming...
SHC3                  0.022   src homology 2 domain-containing transforming prote...
SYK                   0.021   spleen tyrosine kinase isoform 2 
MATK                  0.021   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.021   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.021   megakaryocyte-associated tyrosine kinase isoform a [...
NCK1                  0.020   NCK adaptor protein 1 
SHC4                  0.020   rai-like protein 
SYK                   0.019   spleen tyrosine kinase isoform 1 
FLJ22184              0.019   PREDICTED: hypothetical protein FLJ22184 
RASA1                 0.019   RAS p21 protein activator 1 isoform 1 
RASA1                 0.019   RAS p21 protein activator 1 isoform 2 
FLJ22184              0.019   PREDICTED: hypothetical protein FLJ22184 
PLCG2                 0.019   phospholipase C, gamma 2 
PLCG1                 0.018   phospholipase C, gamma 1 isoform a 
PLCG1                 0.018   phospholipase C, gamma 1 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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