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Search of human proteins with 224809302
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224809302 xeroderma pigmentosum, complementation group C
isoform 2 [Homo sapiens]
(903 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224809302 xeroderma pigmentosum, complementation group C isof... 1830 0.0
gi|224809295 xeroderma pigmentosum, complementation group C isof... 1811 0.0
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 53 1e-06
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 52 2e-06
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 51 4e-06
gi|30795231 brain abundant, membrane attached signal protein 1 [... 51 6e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 50 7e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 50 7e-06
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 50 9e-06
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 50 9e-06
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 50 9e-06
gi|50962882 G patch domain containing 8 [Homo sapiens] 49 2e-05
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 49 2e-05
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 49 3e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 48 5e-05
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 47 6e-05
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 47 6e-05
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 47 1e-04
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 46 1e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 46 1e-04
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 46 1e-04
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 46 2e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 46 2e-04
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 45 2e-04
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 45 2e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 45 2e-04
gi|60097902 filaggrin [Homo sapiens] 45 3e-04
gi|120587019 zinc finger protein 318 [Homo sapiens] 45 3e-04
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 45 3e-04
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 45 3e-04
>gi|224809302 xeroderma pigmentosum, complementation group C isoform
2 [Homo sapiens]
Length = 903
Score = 1830 bits (4739), Expect = 0.0
Identities = 903/903 (100%), Positives = 903/903 (100%)
Query: 1 MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGC 60
MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGC
Sbjct: 1 MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGC 60
Query: 61 SHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNE 120
SHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNE
Sbjct: 61 SHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNE 120
Query: 121 DSNEEEEESENDWEEAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANG 180
DSNEEEEESENDWEEAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANG
Sbjct: 121 DSNEEEEESENDWEEAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANG 180
Query: 181 FYRNNICSQPDLHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQD 240
FYRNNICSQPDLHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQD
Sbjct: 181 FYRNNICSQPDLHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQD 240
Query: 241 NLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKE 300
NLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKE
Sbjct: 241 NLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKE 300
Query: 301 RLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPS 360
RLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPS
Sbjct: 301 RLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPS 360
Query: 361 SSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSD 420
SSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSD
Sbjct: 361 SSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSD 420
Query: 421 EDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDG 480
EDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDG
Sbjct: 421 EDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDG 480
Query: 481 EKAEKRSIAGIDQWLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGW 540
EKAEKRSIAGIDQWLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGW
Sbjct: 481 EKAEKRSIAGIDQWLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGW 540
Query: 541 VRDVTQRYDPVWMTVTRKCRVDAEWWAETLRPYQSPFMDREKKEDLEFQAKHMDQPLPTA 600
VRDVTQRYDPVWMTVTRKCRVDAEWWAETLRPYQSPFMDREKKEDLEFQAKHMDQPLPTA
Sbjct: 541 VRDVTQRYDPVWMTVTRKCRVDAEWWAETLRPYQSPFMDREKKEDLEFQAKHMDQPLPTA 600
Query: 601 IGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARVV 660
IGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARVV
Sbjct: 601 IGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARVV 660
Query: 661 RLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFG 720
RLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFG
Sbjct: 661 RLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFG 720
Query: 721 NVYLFLPSMMPIGCVQLNLPNLHRVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEF 780
NVYLFLPSMMPIGCVQLNLPNLHRVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEF
Sbjct: 721 NVYLFLPSMMPIGCVQLNLPNLHRVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEF 780
Query: 781 KDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTD 840
KDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTD
Sbjct: 781 KDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTD 840
Query: 841 AGGGLSSDEEEGTSSQAEAARILAASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPF 900
AGGGLSSDEEEGTSSQAEAARILAASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPF
Sbjct: 841 AGGGLSSDEEEGTSSQAEAARILAASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPF 900
Query: 901 EQL 903
EQL
Sbjct: 901 EQL 903
>gi|224809295 xeroderma pigmentosum, complementation group C isoform
1 [Homo sapiens]
Length = 940
Score = 1811 bits (4691), Expect = 0.0
Identities = 903/940 (96%), Positives = 903/940 (96%), Gaps = 37/940 (3%)
Query: 1 MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGC 60
MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGC
Sbjct: 1 MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGC 60
Query: 61 SHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNE 120
SHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNE
Sbjct: 61 SHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNE 120
Query: 121 DSNEEEEESENDWEE-------------------------------------AKTRERSE 143
DSNEEEEESENDWEE AKTRERSE
Sbjct: 121 DSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSE 180
Query: 144 KIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPDLHAIGLSIIPAR 203
KIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPDLHAIGLSIIPAR
Sbjct: 181 KIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPDLHAIGLSIIPAR 240
Query: 204 FTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQDNLQTTLERRFAIYSARDDEELVH 263
FTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQDNLQTTLERRFAIYSARDDEELVH
Sbjct: 241 FTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQDNLQTTLERRFAIYSARDDEELVH 300
Query: 264 IFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKP 323
IFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKP
Sbjct: 301 IFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKP 360
Query: 324 KTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGR 383
KTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGR
Sbjct: 361 KTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGR 420
Query: 384 ERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGS 443
ERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGS
Sbjct: 421 ERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGS 480
Query: 444 KSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLEVFCEQEE 503
KSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLEVFCEQEE
Sbjct: 481 KSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLEVFCEQEE 540
Query: 504 KWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDA 563
KWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDA
Sbjct: 541 KWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDA 600
Query: 564 EWWAETLRPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIY 623
EWWAETLRPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIY
Sbjct: 601 EWWAETLRPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIY 660
Query: 624 PETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLA 683
PETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLA
Sbjct: 661 PETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLA 720
Query: 684 EPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLH 743
EPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLH
Sbjct: 721 EPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLH 780
Query: 744 RVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKK 803
RVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKK
Sbjct: 781 RVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKK 840
Query: 804 EKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTDAGGGLSSDEEEGTSSQAEAARIL 863
EKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTDAGGGLSSDEEEGTSSQAEAARIL
Sbjct: 841 EKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTDAGGGLSSDEEEGTSSQAEAARIL 900
Query: 864 AASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPFEQL 903
AASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPFEQL
Sbjct: 901 AASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPFEQL 940
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/208 (26%), Positives = 86/208 (41%), Gaps = 20/208 (9%)
Query: 293 KGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCR--PSAKGKRNK 350
+G + K++ P G + EN KPK + K E+ A R PS KGK
Sbjct: 951 EGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKI-- 1008
Query: 351 GGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVAS-RVSYKEESGSDEAGSGSDFE 409
K SS +D DK + A + P S +++ S E+ S +
Sbjct: 1009 ----KSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQN 1064
Query: 410 LSSGEASDP-------SDEDSEPGPPKQRKAPA-PQRTKAGSKSASRTHRGSHRKDPSLP 461
S EA P SD+DS+ P +++ P+ +++ S + R+H G D S P
Sbjct: 1065 KSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEND-SRP 1123
Query: 462 AASSSSS--SSKRGKKMCSDGEKAEKRS 487
A+ S+ S S+RG G+ + S
Sbjct: 1124 ASPSAESDHESERGSDNEGSGQGSGNES 1151
Score = 40.4 bits (93), Expect = 0.007
Identities = 42/145 (28%), Positives = 58/145 (40%), Gaps = 37/145 (25%)
Query: 353 RKKRSKPSSSE---EDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFE 409
+KKR K S SE EDE G++++K +R P G E GSD D E
Sbjct: 934 KKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKG-------------EEGSD------DDE 974
Query: 410 LSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSS 469
+G P + P +++KAP P+R K K S SSS S
Sbjct: 975 TENG----PKPKKRRPPKAEKKKAPKPERLPPSMKG----------KIKSKAIISSSDDS 1020
Query: 470 SKRGK-KMCSDGEKAEKRSIAGIDQ 493
S K K+ +G S + D+
Sbjct: 1021 SDEDKLKIADEGHPRNSNSNSDSDE 1045
Score = 34.7 bits (78), Expect = 0.41
Identities = 39/152 (25%), Positives = 60/152 (39%), Gaps = 30/152 (19%)
Query: 3 RKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDE----KPPKKSLLSKVSQGKRKR 58
R++ +G E G + + K K + R + EE + +DE PKK K
Sbjct: 937 RRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAE------ 990
Query: 59 GCSHPGGSADGPAKKKVAKVTVKSENLK-VIKDEALSDGDDLRDFPSDLKKAHH-LKRGA 116
KKK K ++K IK +A+ D LK A R +
Sbjct: 991 -------------KKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNS 1037
Query: 117 TMNEDSNEEEE-----ESENDWEEAKTRERSE 143
N DS+E+E+ SE+D +E + + SE
Sbjct: 1038 NSNSDSDEDEQRKKCASSESDSDENQNKSGSE 1069
Score = 33.9 bits (76), Expect = 0.70
Identities = 45/196 (22%), Positives = 80/196 (40%), Gaps = 35/196 (17%)
Query: 322 KPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPH 381
K K KG+ E+ +G + K+ K R + + S +++ G K +K RRP
Sbjct: 934 KKKRRKGSGSEQ---EGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKK---RRPP 987
Query: 382 GRERRVASRV-----SYKEE-------SGSDEAGSGSDFELSSGEASDPSDEDSEPGPPK 429
E++ A + S K + S SD++ +++ S+ +S+ +
Sbjct: 988 KAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDE 1047
Query: 430 QRKAPAPQRT-------KAGSKSAS----RTHRGSHRKDPSLPAASSSSSSSKRGKKMCS 478
QRK A + K+GS++ S R R D P+ S S++ S
Sbjct: 1048 QRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ-----S 1102
Query: 479 DGEKAEK-RSIAGIDQ 493
D E + RS +G+ +
Sbjct: 1103 DNESVQSGRSHSGVSE 1118
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 52.4 bits (124), Expect = 2e-06
Identities = 37/169 (21%), Positives = 68/169 (40%), Gaps = 3/169 (1%)
Query: 321 TKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRP 380
++ + S + + ++ R S K + G K S S G + + ++ +
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 381 HGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTK 440
R ++ SR KE+S S +G S +A + + G PK R +P+ ++K
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSR-SPSRHKSK 297
Query: 441 AGSKSASRTHRGSHRKDPSLPAASSSSSS--SKRGKKMCSDGEKAEKRS 487
+ S+S S+ R K S+ S S R + G ++ RS
Sbjct: 298 SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Score = 48.9 bits (115), Expect = 2e-05
Identities = 38/171 (22%), Positives = 76/171 (44%), Gaps = 9/171 (5%)
Query: 293 KGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGG 352
K + S+ R + GGS S ++ K K K ++ EE+ ++ R ++ R +G
Sbjct: 325 KSLRQSRSR-SRSKGGSRSRSRSRSKSKDKRKGRKRSR-EESRSRSRSRSKSERSRKRGS 382
Query: 353 RKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSS 412
++ SS ++ + D+ + + R +ER A S + E + +G++ E S
Sbjct: 383 KRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRS 442
Query: 413 GEASDPSDEDSEPGPPKQRKAPAPQ-------RTKAGSKSASRTHRGSHRK 456
S+ + + P + R A + R+++ S+S SR+ SH +
Sbjct: 443 RSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/192 (21%), Positives = 75/192 (39%), Gaps = 7/192 (3%)
Query: 296 KPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKK 355
KP R + S + S+ H++ S+ + + +K R S G R++ +
Sbjct: 176 KPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSR-SRSGSRSRSKSRS 234
Query: 356 RSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEA 415
RS+ S + E ++ ++ R H A + K + ++E +D + ++
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHS-----AGKSRSKSKDQAEEKIQNND-NVGKPKS 288
Query: 416 SDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKK 475
PS S+ + + + K GS S R+ S R+ S + S S R +
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRS 348
Query: 476 MCSDGEKAEKRS 487
D K KRS
Sbjct: 349 KSKDKRKGRKRS 360
Score = 47.0 bits (110), Expect = 8e-05
Identities = 41/202 (20%), Positives = 76/202 (37%), Gaps = 7/202 (3%)
Query: 293 KGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKG-KRNKG 351
K K S R + S + + +E + S+G QE++ + R +KG R++
Sbjct: 285 KPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS 344
Query: 352 GRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELS 411
+ +SK + + ++ R R R+ S+ K S + +D S
Sbjct: 345 RSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS 404
Query: 412 SGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTH-RGSHRKDPSLPAASSSSSSS 470
+ S E ++ + AG+ +R+ R + + P+LP+ S S S S
Sbjct: 405 RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS 464
Query: 471 -----KRGKKMCSDGEKAEKRS 487
R K ++ RS
Sbjct: 465 ASKTRSRSKSRSRSASRSPSRS 486
Score = 40.0 bits (92), Expect = 0.010
Identities = 38/164 (23%), Positives = 71/164 (43%), Gaps = 19/164 (11%)
Query: 9 GEPRGRELRSQKSKAKSKARR-----EEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHP 63
G+P+ R KSK+KS++R EEE+ + + +KSL S+ + K
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSK------ 337
Query: 64 GGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNEDSN 123
GGS + +K K + K ++E+ S S K KRG+ + +
Sbjct: 338 GGSRSRSRSRSKSK--DKRKGRKRSREESRSRS------RSRSKSERSRKRGSKRDSKAG 389
Query: 124 EEEEESENDWEEAKTRERSEKIKLEFETYLRRAMKRFNKGVHED 167
+++ + D + +++R S + E E + +R +G E+
Sbjct: 390 SSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESEN 433
Score = 35.4 bits (80), Expect = 0.24
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 34/200 (17%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
+S K + PSKE+ + + ++ S+ +K + + + + K R +
Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSK-----SKDQAEEKIQNNDNVGKPKSRSPS--- 292
Query: 348 RNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSD 407
R+K K RS+ QE+ + G R S+ +S S G
Sbjct: 293 RHKSKSKSRSR------------SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGS 340
Query: 408 FELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSS 467
S S +D G + R+ + R+++ SKS RGS R S +
Sbjct: 341 ---RSRSRSRSKSKDKRKGRKRSRE-ESRSRSRSRSKSERSRKRGSKR--------DSKA 388
Query: 468 SSSKRGKKMCSDGEKAEKRS 487
SSK+ KK D ++++ RS
Sbjct: 389 GSSKKKKK--EDTDRSQSRS 406
Score = 30.8 bits (68), Expect = 5.9
Identities = 24/138 (17%), Positives = 50/138 (36%), Gaps = 23/138 (16%)
Query: 5 RAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPG 64
+++ + R R +S++KS++R + E + P K ++ R SH
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSK---------EKSRSRSHSA 262
Query: 65 GSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNE 124
G + +K + +E + + D++ S H K +
Sbjct: 263 GKSRSKSKDQA--------------EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERR 308
Query: 125 EEEESENDWEEAKTRERS 142
EEE +++E+S
Sbjct: 309 VEEEKRGSVSRGRSQEKS 326
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 51.2 bits (121), Expect = 4e-06
Identities = 64/222 (28%), Positives = 87/222 (39%), Gaps = 39/222 (17%)
Query: 274 LLTRLVLSLQPIPLKSAT----AKG-----KKPSKERLTADPGGSSETSSQVLENHTKPK 324
LL + ++L PL S AKG K E L +P S E S +E T
Sbjct: 2015 LLQQYQVALSASPLTSLPRLLDAKGIILEEMKVKSENLKEEPQSSEEESMSSVETRTL-- 2072
Query: 325 TSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRE 384
K E K P A G + GG+ E D + + P ++
Sbjct: 2073 ----IKSEPVSPKNGVLPQATGDQKSGGK--------CETDRRMVAARTEPLTPNPASKK 2120
Query: 385 RRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSK 444
RV R S ES SD S SD E SS + S S + +++GS
Sbjct: 2121 PRVHKRGS---ESSSD---SDSDSERSSCSSRSSSSSSSS----------SCSHSRSGSS 2164
Query: 445 SASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKR 486
S+S + S S +SSSSSSS ++ SD E+A+KR
Sbjct: 2165 SSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKR 2206
Score = 32.0 bits (71), Expect = 2.7
Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 363 EEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDED 422
EED D+++K G E + S E S +A SGSD SS E SD S+ED
Sbjct: 2828 EEDSRIKDQEDKG------GTEPSPLNENSTDEGSEKADASSGSDSTSSSSEDSDSSNED 2881
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 50.8 bits (120), Expect = 6e-06
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 11/215 (5%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
+ A K KK ++ T + G E+ Q + K K ++ K +G+
Sbjct: 17 EKAKEKDKK-AEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAE---EKEGE 72
Query: 348 RNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSD 407
++ K+ + + E+ EG + KA + +E+ + E + EA +
Sbjct: 73 KDAAAAKEEAPKAEPEKTEGAAEA--KAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPA 130
Query: 408 FELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPS---LPAAS 464
+ +PS E+ EP + APA Q TK+ AS + GS PS PAA+
Sbjct: 131 ESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAAT 190
Query: 465 SSSSSSKRGKKMCSDGE--KAEKRSIAGIDQWLEV 497
+ SS+ + + + E K + A DQ + V
Sbjct: 191 EAPSSTPKAQGPAASAEEPKPVEAPAANSDQTVTV 225
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 50.4 bits (119), Expect = 7e-06
Identities = 53/229 (23%), Positives = 89/229 (38%), Gaps = 29/229 (12%)
Query: 286 PLKSATAKGKK---PSKERLTADPGGSSETSSQVLENHTKPK-TSKGT--KQEETFAKGT 339
P K+ +K P+K+ + S SS+ E +KP T+K + K T
Sbjct: 340 PTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPA 399
Query: 340 CRPSAKGKRNKGGRKK---RSKPSSSEEDEGPGDKQEKATQ----RRPHGRERRVASRVS 392
+P+A K+ GG +K R SSS E+E ++EK + +P + S +
Sbjct: 400 VKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPA 459
Query: 393 YKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRG 452
+ GS ++ S SD S E S + P K AP + + K + +
Sbjct: 460 KQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNS 519
Query: 453 SHRKD----------------PSLPAASSSSSSSKRGKKMCSDGEKAEK 485
S D P P A+ +S+ + + K + E+ E+
Sbjct: 520 SSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEE 568
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/165 (31%), Positives = 68/165 (41%), Gaps = 25/165 (15%)
Query: 342 PSAKGKRNKGGRKKRSKPSSSEEDE--GPGDKQEKATQRR---PHGRERRVASRVSYKEE 396
P AK K K S+ SS EE+E GP K+ +R P G+ AS S EE
Sbjct: 73 PVAK-KAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEE 131
Query: 397 SGSDE-----------------AGSGSDFELSSGEASDPSDEDSEPGPPKQRKAP-APQR 438
S D+ A + + + SD SE PPK +K P
Sbjct: 132 SSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVT 191
Query: 439 TKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKA 483
KA +K+ + R + K + AASSSSSSS S+ EKA
Sbjct: 192 VKAQTKAPPKPARAAP-KIANGKAASSSSSSSSSSSSDDSEEEKA 235
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/198 (21%), Positives = 79/198 (39%), Gaps = 8/198 (4%)
Query: 283 QPIP--LKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTC 340
QP+ +K K P K+ ++D S + + +N KPK + T + +T K
Sbjct: 144 QPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQ-KPKITPVTVKAQT--KAPP 200
Query: 341 RPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQR-RPHGRERRVASRVSYKEESGS 399
+P+ + G+ S SSS ++EKA + +++V ++ K +
Sbjct: 201 KPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTP 260
Query: 400 DEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPA--PQRTKAGSKSASRTHRGSHRKD 457
S S+ S E ++PGP P+ P + G++ + +
Sbjct: 261 TRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVE 320
Query: 458 PSLPAASSSSSSSKRGKK 475
S ++ S SSS+ KK
Sbjct: 321 SSEDSSDESDSSSEEEKK 338
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 3/169 (1%)
Query: 304 ADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSE 363
AD S E SS E TK K TK + T P+ + + S SSSE
Sbjct: 421 ADSSSSEEESSSSEEEKTK-KMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSE 479
Query: 364 EDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDS 423
E+E K A +++P A + G E+ + S + SS E +
Sbjct: 480 EEEEKTSKS--AVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKG 537
Query: 424 EPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKR 472
P P + T K+A + K + S S S KR
Sbjct: 538 SPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKR 586
Score = 42.7 bits (99), Expect = 0.002
Identities = 47/205 (22%), Positives = 75/205 (36%), Gaps = 19/205 (9%)
Query: 285 IPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSA 344
+P K AK + T S ++SS E KP +K + P
Sbjct: 243 VPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSV-PPPSAPPPK 301
Query: 345 KGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKE-------ES 397
K + +K K E E D+ + +++ + V S+ + K ES
Sbjct: 302 KSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAES 361
Query: 398 GSDEAGSGS--DFELSSGEASDPSDEDSEPG----PPKQRKAPAPQRTKAGSKSASRTHR 451
SD + S S D E S A + ++P P + A AP++ G +
Sbjct: 362 SSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL---- 417
Query: 452 GSHRKDPSLPAASSSSSSSKRGKKM 476
+ + D S SSSS ++ KKM
Sbjct: 418 -TRKADSSSSEEESSSSEEEKTKKM 441
Score = 40.4 bits (93), Expect = 0.007
Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 13/145 (8%)
Query: 4 KRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVS--------QGK 55
K++ G +P + + Q+ S+ +E + + E++KPP K+++SK + +
Sbjct: 301 KKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAE 360
Query: 56 RKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRG 115
S S D A K A T S N K + ++ + + ++
Sbjct: 361 SSSDSSDSDSSEDDEAPSKPAGTTKNSSN----KPAVTTKSPAVKPAAAPKQPVGGGQKL 416
Query: 116 ATMNEDSNEEEEESENDWEEAKTRE 140
T DS+ EEES + EE KT++
Sbjct: 417 LTRKADSSSSEEESSSS-EEEKTKK 440
Score = 39.7 bits (91), Expect = 0.013
Identities = 46/202 (22%), Positives = 78/202 (38%), Gaps = 26/202 (12%)
Query: 282 LQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCR 341
+Q P K A K R+ PG ++ +S+ + Q++ + +
Sbjct: 97 VQGPPAKKAAVPAK-----RVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVK 151
Query: 342 PSAKGKR--NKGGRKKRSKPSSSEEDEGPGDKQEKAT------QRRPHGRERRVASRVSY 393
P AK + K + S SS EDE P +++ K T Q + + R A +++
Sbjct: 152 PQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIAN 211
Query: 394 KEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGS 453
+ + S + SS +SD S+E+ PK+ KA K+A+ R S
Sbjct: 212 GKAASSSSSS-------SSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKS 264
Query: 454 HRKDPSLPAASSSSSSSKRGKK 475
+ SSS + KK
Sbjct: 265 SSSE------DSSSDEEEEQKK 280
Score = 36.6 bits (83), Expect = 0.11
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 30/142 (21%)
Query: 2 ARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPK-----------KSLLS- 49
A K+ GG G++L ++K+ + S EEE + E+EK K K+ LS
Sbjct: 405 APKQPVGG---GQKLLTRKADSSSS----EEESSSSEEEKTKKMVATTKPKATAKAALSL 457
Query: 50 ---KVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDL 106
+ QG R S++ ++K +K VK + KV A S P+
Sbjct: 458 PAKQAPQGSRDSSSDSDSSSSE-EEEEKTSKSAVKKKPQKVAGGAAPSK-------PASA 509
Query: 107 KKAHHLKRGATMNEDSNEEEEE 128
KK ++ ++DS+EEEEE
Sbjct: 510 KKGKAESSNSSSSDDSSEEEEE 531
Score = 36.2 bits (82), Expect = 0.14
Identities = 45/207 (21%), Positives = 78/207 (37%), Gaps = 23/207 (11%)
Query: 286 PLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAK 345
P +A A P+K+ SS++ S E + + K++ G PS
Sbjct: 447 PKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKP 506
Query: 346 GKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHG----------RERRVASRVSYKE 395
KG + + SS + E +K + RP + A++ S +E
Sbjct: 507 ASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEE 566
Query: 396 ESGSDEAG-----SGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQ---RTKAGSKSAS 447
E +A SGS + EA+ +++E K+ K P + K G K AS
Sbjct: 567 EEEKKKAAVVVSKSGSLKKRKQNEAA----KEAETPQAKKIKLQTPNTFPKRKKGEKRAS 622
Query: 448 RTHRGSHRKDPSLPA-ASSSSSSSKRG 473
R ++ + + + +S +KRG
Sbjct: 623 SPFRRVREEEIEVDSRVADNSFDAKRG 649
Score = 30.8 bits (68), Expect = 5.9
Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 8/141 (5%)
Query: 8 GGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPK--KSLLSKVSQGKRKRGCSHPGG 65
G +P+ + ++ KAKS + + D+ +++PPK K ++ V+ + + P
Sbjct: 149 GVKPQAKAAKAPPKKAKSS----DSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPAR 204
Query: 66 SADGPAKKKVAKVTVKSENLKVIKD--EALSDGDDLRDFPSDLKKAHHLKRGATMNEDSN 123
+A A K A + S + D E + + P A + AT +
Sbjct: 205 AAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKS 264
Query: 124 EEEEESENDWEEAKTRERSEK 144
E+S +D EE + + K
Sbjct: 265 SSSEDSSSDEEEEQKKPMKNK 285
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 50.4 bits (119), Expect = 7e-06
Identities = 51/212 (24%), Positives = 90/212 (42%), Gaps = 23/212 (10%)
Query: 287 LKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKG 346
+KS + +KP + ++ P + E + K + K +K+EE K +P +
Sbjct: 820 VKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP---KTEEKKDSKKEEAPKKEAPKPKVEE 876
Query: 347 KRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGS 406
K+ K + ++++E DK++ T E+ ++V KE++ E +
Sbjct: 877 KKEPAVEKPKESKVEAKKEEAE-DKKKVPTP------EKEAPAKVEVKEDAKPKEKTEVA 929
Query: 407 DFELSSGEASDPSD--EDSEPGP----PKQRKAPAPQ---RTKAGSKSASRTHRGSHRKD 457
E +A +PS E E P K+ KA P+ +T+A +K +T K+
Sbjct: 930 KKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT----LSKE 985
Query: 458 PSLPAASSSSSSSKRGKKMCSDGEKAEKRSIA 489
PS P A + SS +K EKA + A
Sbjct: 986 PSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 40.4 bits (93), Expect = 0.007
Identities = 41/206 (19%), Positives = 79/206 (38%), Gaps = 12/206 (5%)
Query: 284 PIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPS 343
P +KS K K P+KE + P E S E P K ++ ++ AK +
Sbjct: 541 PAEVKSPE-KAKSPAKEEAKSPP----EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 344 AKGKRNKGGRKKRSKPSSSEEDEGPGDKQE--KATQRRPHGRERRVASRVSYKEESGSDE 401
A+ K +++K EE + P + + K + P + ++ KEE+ S E
Sbjct: 596 AEAKS-----PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650
Query: 402 AGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLP 461
+ E + S +E P++ K+P K+ K+ S + + +
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710
Query: 462 AASSSSSSSKRGKKMCSDGEKAEKRS 487
+ S ++ K + K +++
Sbjct: 711 PVKEEAKSPEKAKSPVKEEAKTPEKA 736
Score = 40.0 bits (92), Expect = 0.010
Identities = 46/218 (21%), Positives = 91/218 (41%), Gaps = 19/218 (8%)
Query: 282 LQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPK--TSKGTKQEETFAKGT 339
L IP S K K K ++ SE + ++E T+ T + T++EE AK
Sbjct: 426 LPKIPSVSTHIKVKSEEKIKVVE----KSEKETVIVEEQTEETQVTEEVTEEEEKEAK-- 479
Query: 340 CRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGS 399
+GK +GG ++ ++ EE + P ++ + ++ + A + +
Sbjct: 480 ---EEEGKEEEGGEEEEAE-GGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEK 535
Query: 400 DEAGSGSDFELSSGEASDPSDEDSEPGPP------KQRKAPAPQRTKAGSKSASRTHRGS 453
+EA S ++ + S +A P+ E+++ P ++ K+PA ++ +KS ++ S
Sbjct: 536 EEAKSPAEVK-SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594
Query: 454 HRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGI 491
+ S A S + K E +S A +
Sbjct: 595 PAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632
Score = 38.1 bits (87), Expect = 0.037
Identities = 53/222 (23%), Positives = 83/222 (37%), Gaps = 37/222 (16%)
Query: 285 IPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSA 344
+ +KS AK + R AD + S V E P+ +K +E+ A P
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKF-PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP-- 815
Query: 345 KGKRNKGGRKKRSKPSSSEEDEGPGDKQ-----EKATQRRPHGRERRVASRVSYKEESGS 399
KK S +E+E P + + +KA + + + + S KEE+
Sbjct: 816 ---------KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866
Query: 400 DEAGSGSDFEL----------SSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRT 449
EA E S EA ED + P +++APA K +K +T
Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT 926
Query: 450 H------RGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEK 485
+ K+PS PA ++ K+ K EKA+K
Sbjct: 927 EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK----EEKAKK 964
Score = 36.6 bits (83), Expect = 0.11
Identities = 49/203 (24%), Positives = 79/203 (38%), Gaps = 22/203 (10%)
Query: 284 PIPLKSATAKGKKPSKE--RLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCR 341
P +KS K K P+KE + A+ + S V E P +K +EE + +
Sbjct: 575 PAEVKSPE-KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK 633
Query: 342 PSAKGKR-NKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVS-------- 392
K K K K K S E++E ++ K+ + + S V
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693
Query: 393 ----YKEESGSDE-AGSGSDFELSSGE-ASDPSDEDSEPGP----PKQRKAPAPQRTKAG 442
KEE+ S E A S E S E A P E+++ P + +A +P++ K+
Sbjct: 694 AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP 753
Query: 443 SKSASRTHRGSHRKDPSLPAASS 465
K+ + + K P+ A S
Sbjct: 754 EKAKTLDVKSPEAKTPAKEEARS 776
Score = 36.6 bits (83), Expect = 0.11
Identities = 39/154 (25%), Positives = 62/154 (40%), Gaps = 17/154 (11%)
Query: 2 ARKRAAGGEPRGRELRSQKS-----KAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKR 56
A + A P+ E + K K K + EE++E A E K K + ++ K+
Sbjct: 842 AEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK 901
Query: 57 KRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGA 116
K P + PAK +V + E +V K E DD + + K K A
Sbjct: 902 K----VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP----DDAK--AKEPSKPAEKKEAA 951
Query: 117 TMNEDSNEE--EEESENDWEEAKTRERSEKIKLE 148
+D+ EE ++ E EAK +E + + E
Sbjct: 952 PEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Score = 34.7 bits (78), Expect = 0.41
Identities = 38/200 (19%), Positives = 71/200 (35%), Gaps = 19/200 (9%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
+ T + +K +KE + G E ++ E TK ++ E AK + AK
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP 527
Query: 348 RNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSD 407
+K EE + P + + + P KEE+ S +
Sbjct: 528 AE-------AKSPEKEEAKSPAEVKSPEKAKSPA------------KEEAKSPPEAKSPE 568
Query: 408 FELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSS 467
E + A S E ++ ++ K+PA ++ +KS + S + S + S
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628
Query: 468 SSSKRGKKMCSDGEKAEKRS 487
+ + + K E +S
Sbjct: 629 PAEVKSPEKAKSPTKEEAKS 648
Score = 34.7 bits (78), Expect = 0.41
Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 10/148 (6%)
Query: 2 ARKRAAGGEPRGRELRSQ---KSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKR 58
A+ A P E +S KS K+K+ +EE + E + P K+ S ++
Sbjct: 524 AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK 583
Query: 59 GCSHPGGSADGPAKKK---VAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRG 115
S A PA+ K AK VK E EA S + P+++K K
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS--PAEAKSPVKEEAKSPAEVKSPEKAK-- 639
Query: 116 ATMNEDSNEEEEESENDWEEAKTRERSE 143
+ E++ E+ + EEAK+ E+++
Sbjct: 640 SPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Score = 32.3 bits (72), Expect = 2.0
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 6/109 (5%)
Query: 30 EEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIK 89
EEEE++A E+E ++ + ++G + S P A P K+ AK VK E
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKE--AKSPVKEEAKS--P 527
Query: 90 DEALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEAKT 138
EA S + P+++K K A E++ E + EEAK+
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPA--KEEAKSPPEAKSPEKEEAKS 574
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 50.1 bits (118), Expect = 9e-06
Identities = 48/188 (25%), Positives = 88/188 (46%), Gaps = 12/188 (6%)
Query: 288 KSATAKGKKPS-KERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKG 346
KS K S K+R++ GSS+ S++ +++ K + +K + +E +K + K
Sbjct: 132 KSQEVSSKSGSMKDRIS----GSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKE 187
Query: 347 KRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGS 406
+ K G K RSK S + + K + +RR R+ + S K++ A G
Sbjct: 188 RELKSGHKDRSK-SHRKRETPKSYKTVDSPKRRSRSPHRKWSD--SSKQDDSPSGASYGQ 244
Query: 407 DFELSSGEASDPSDEDS---EPGPPKQRKAPA-PQRTKAGSKSASRTHRGSHRKDPSLPA 462
D++LS + S+ DS PG +R++ + P + + +S++R+ R+ S+
Sbjct: 245 DYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSP 304
Query: 463 ASSSSSSS 470
S SSS
Sbjct: 305 YSRRRSSS 312
Score = 31.6 bits (70), Expect = 3.5
Identities = 29/129 (22%), Positives = 48/129 (37%), Gaps = 4/129 (3%)
Query: 17 RSQKSKAKSKARREEEEEDAFEDEKPPKKSLL-SKVSQGKRKRGCSHPGGSADGPAKKKV 75
R S +K K + + P S L +++S+ K++R + DG K
Sbjct: 364 RHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGS 423
Query: 76 AKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEE 135
+ EN V EA G + + P +K +N E ++ +D +
Sbjct: 424 PVFLPRKENSSV---EAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
Query: 136 AKTRERSEK 144
K E SEK
Sbjct: 481 VKLDENSEK 489
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 50.1 bits (118), Expect = 9e-06
Identities = 48/188 (25%), Positives = 88/188 (46%), Gaps = 12/188 (6%)
Query: 288 KSATAKGKKPS-KERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKG 346
KS K S K+R++ GSS+ S++ +++ K + +K + +E +K + K
Sbjct: 132 KSQEVSSKSGSMKDRIS----GSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKE 187
Query: 347 KRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGS 406
+ K G K RSK S + + K + +RR R+ + S K++ A G
Sbjct: 188 RELKSGHKDRSK-SHRKRETPKSYKTVDSPKRRSRSPHRKWSD--SSKQDDSPSGASYGQ 244
Query: 407 DFELSSGEASDPSDEDS---EPGPPKQRKAPA-PQRTKAGSKSASRTHRGSHRKDPSLPA 462
D++LS + S+ DS PG +R++ + P + + +S++R+ R+ S+
Sbjct: 245 DYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSP 304
Query: 463 ASSSSSSS 470
S SSS
Sbjct: 305 YSRRRSSS 312
Score = 31.6 bits (70), Expect = 3.5
Identities = 29/129 (22%), Positives = 48/129 (37%), Gaps = 4/129 (3%)
Query: 17 RSQKSKAKSKARREEEEEDAFEDEKPPKKSLL-SKVSQGKRKRGCSHPGGSADGPAKKKV 75
R S +K K + + P S L +++S+ K++R + DG K
Sbjct: 364 RHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGS 423
Query: 76 AKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEE 135
+ EN V EA G + + P +K +N E ++ +D +
Sbjct: 424 PVFLPRKENSSV---EAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK 480
Query: 136 AKTRERSEK 144
K E SEK
Sbjct: 481 VKLDENSEK 489
>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
[Homo sapiens]
Length = 531
Score = 50.1 bits (118), Expect = 9e-06
Identities = 42/181 (23%), Positives = 69/181 (38%), Gaps = 15/181 (8%)
Query: 309 SSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGP 368
+ E LENH + + + E ++ GG + + SS E EG
Sbjct: 363 AQEARKAQLENHEPEEEEEEEMETE-------------EKEAGGSDEEQEKGSSSEKEGS 409
Query: 369 GDKQEKATQRRPHG-RERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDE-DSEPG 426
D+ + R G R+ S ++ES DEA + D E G +D D+ DS+
Sbjct: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
Query: 427 PPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKR 486
Q + + + +GS + R R P+ S S+ + SD +A+
Sbjct: 470 DRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
Query: 487 S 487
S
Sbjct: 530 S 530
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 49.3 bits (116), Expect = 2e-05
Identities = 40/194 (20%), Positives = 78/194 (40%), Gaps = 11/194 (5%)
Query: 293 KGKKPSKERLTADPGGSSETSSQVLE----NHTKPKTSKGTKQEETFAKGTCRPSAKGKR 348
K K+ E++ GG + + N +P S G++ E+T + GK
Sbjct: 613 KSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKS 672
Query: 349 NKGGRKKRSKPSSSEEDEGPGDKQEKATQRR--PHGRERRVASRVSYKEESGSDEAGSGS 406
++ +KK+ K SS + + D +EK+++ ++R+ R K + +D
Sbjct: 673 HRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPK 732
Query: 407 DFELSSGEASDPSDEDSEPGPPKQRKAPAPQ-----RTKAGSKSASRTHRGSHRKDPSLP 461
SG + P ++R PA + + + G S+S+ H G K P
Sbjct: 733 PEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPP 792
Query: 462 AASSSSSSSKRGKK 475
++ + +KR +
Sbjct: 793 SSCQRRAGTKRSSR 806
Score = 43.9 bits (102), Expect = 7e-04
Identities = 51/209 (24%), Positives = 85/209 (40%), Gaps = 31/209 (14%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
KS+ A+ + SK+R + + + P S+ + E G+ P + +
Sbjct: 698 KSSKAESGEKSKKR---------KKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRR 748
Query: 348 RNKGGRKKRSKP----SSSEEDEGPGDKQEKATQRRPHGRE-------RRV----ASRVS 392
R + ++RS P SS ++DEG G + R H E RR +SR S
Sbjct: 749 RAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSS 808
Query: 393 YKEE--SGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTH 450
++ + SG +++ S L S S+E+ E + R+++G + +S H
Sbjct: 809 HRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSR---SRSRSGRRHSS--H 863
Query: 451 RGSHRKDPSLPAASSSSSSSKRGKKMCSD 479
R S R S ASS S R + D
Sbjct: 864 RSSRRSYSSSSDASSDQSCYSRQRSYSDD 892
Score = 40.0 bits (92), Expect = 0.010
Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 16/166 (9%)
Query: 309 SSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGP 368
S + SS L + + S+ ++E++ ++ + S G+R+ R R SSS +
Sbjct: 820 SDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSD---- 875
Query: 369 GDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPP 428
++ + + R+R SY ++S SD + S + SD SD S
Sbjct: 876 -----ASSDQSCYSRQR------SYSDDSYSDYSDRSRRHSKRSHD-SDDSDYASSKHRS 923
Query: 429 KQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGK 474
K+ K + + S S SR+ SH ++ S S SSS R +
Sbjct: 924 KRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSR 969
Score = 36.6 bits (83), Expect = 0.11
Identities = 42/191 (21%), Positives = 62/191 (32%), Gaps = 12/191 (6%)
Query: 305 DPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGG---------RKK 355
D GG +S K + + Q K + R S + + + G R
Sbjct: 770 DEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLH 829
Query: 356 RSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEA 415
+ PS E+E D + ++ R R + R S + S S +A S
Sbjct: 830 QKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSY 889
Query: 416 SDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKK 475
SD S D + R+ S AS HR K S S S S R +
Sbjct: 890 SDDSYSDYS---DRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRS 946
Query: 476 MCSDGEKAEKR 486
E++ R
Sbjct: 947 RSHTRERSRSR 957
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 48.9 bits (115), Expect = 2e-05
Identities = 64/259 (24%), Positives = 93/259 (35%), Gaps = 51/259 (19%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
K K K+ + G + + KP T KGT EE G R
Sbjct: 334 KKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIAR------ 387
Query: 348 RNKGGRKKRS----KPSSSEEDEGPGDKQEKATQRRPHGRE-RRVASRVSYKEESGSDEA 402
NK G K R+ KP + D + + +G + +RV+SR E+ SDE
Sbjct: 388 ENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEK 447
Query: 403 GSGSDF--ELSSGEAS-------------DPSDEDSEPGPPKQRKAPAPQRTKA------ 441
S S+ E GE S +EDS G ++ K RT +
Sbjct: 448 DSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPG 507
Query: 442 ----------------GSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEK 485
G K +T S RK P+L A S S + DGEK+
Sbjct: 508 LKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKS-- 565
Query: 486 RSIAGIDQ-WLEVFCEQEE 503
R+++ Q L+ C++E+
Sbjct: 566 RTVSSQKQPALKAICDKED 584
Score = 47.4 bits (111), Expect = 6e-05
Identities = 59/223 (26%), Positives = 87/223 (39%), Gaps = 23/223 (10%)
Query: 275 LTRLVLSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEET 334
++R V S +P LK+ + K G S T S +P K T+ E+
Sbjct: 258 ISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS-----FDQPPGLKATRDEKD 312
Query: 335 FAKGTCRPSAKGKRNK--GGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGR-ERRVASRV 391
R G++ + RKK + ++S+E D T+ + G R+V+S+
Sbjct: 313 SLLNIARGKKNGEKTRRVSSRKKPALKATSDEK----DSFSNITRGKKDGEISRKVSSQK 368
Query: 392 SYKEESGSDEAGS--GSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKA-----GSK 444
+ SDE S G E GE S + PG KA + ++ G K
Sbjct: 369 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPG----LKASSDEKDSVLNIARGKK 424
Query: 445 SASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
+T R S RK PSL A S S + DGE + K S
Sbjct: 425 YGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVS 467
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/218 (25%), Positives = 86/218 (39%), Gaps = 26/218 (11%)
Query: 288 KSATAKGKKPSKERLTADPGGSS-ETSSQVLE-------NHTKPKTSKGTKQEETFAKGT 339
KS T +K + +D S+ T++++ + + K + K T EE
Sbjct: 156 KSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNI 215
Query: 340 CRPSAKGKRN---KGGRKKRSKPSSSEEDEGPG---DKQEKATQRRPHGRERRVASRVSY 393
G+++ +K K +S E+D +K++ R ++ S
Sbjct: 216 ATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSV 275
Query: 394 KEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQR-KAPAPQRTKAGSKSASRTHRG 452
KE+S + A D GE S D PG R + + G K+ +T R
Sbjct: 276 KEDSVLNIAREKKD-----GEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRV 330
Query: 453 SHRKDPSLPAAS---SSSSSSKRGKKMCSDGEKAEKRS 487
S RK P+L A S S S+ RGKK DGE + K S
Sbjct: 331 SSRKKPALKATSDEKDSFSNITRGKK---DGEISRKVS 365
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 48.5 bits (114), Expect = 3e-05
Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 10/190 (5%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
K+ AKG + K++ +D ++ E S G+ + + + + +
Sbjct: 237 KAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEE 296
Query: 348 RNKGGRKKRSKPSSSEEDEGP-GDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGS 406
KG ++ SEE++ P DK+E+ ++ P +E++ + + S+E+ S
Sbjct: 297 GPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKK-------RRKDSSEESDSSE 349
Query: 407 DFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSS 466
+ ++ S EAS + PPK+ + P+ ++ S+ + + G +L AA+S
Sbjct: 350 ESDIDS-EASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSS-TLRAAASK 407
Query: 467 SSSSKRGKKM 476
KR +M
Sbjct: 408 LEQGKRVSEM 417
Score = 32.3 bits (72), Expect = 2.0
Identities = 31/150 (20%), Positives = 55/150 (36%), Gaps = 31/150 (20%)
Query: 342 PSAKGKRN--KGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGS 399
P AK K KGGRKK+ K S +E ++++
Sbjct: 232 PKAKKKAPLAKGGRKKKKKKGSDDE---------------------------AFEDSDDG 264
Query: 400 DEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHR-KDP 458
D G D+ +S G +S + +S+ P+Q + P ++ S S + K+
Sbjct: 265 DFEGQEVDY-MSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEE 323
Query: 459 SLPAASSSSSSSKRGKKMCSDGEKAEKRSI 488
+ + KR K + + +E+ I
Sbjct: 324 EEEKKAPTPQEKKRRKDSSEESDSSEESDI 353
Score = 30.8 bits (68), Expect = 5.9
Identities = 35/168 (20%), Positives = 61/168 (36%), Gaps = 23/168 (13%)
Query: 356 RSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFEL----- 410
R + ++EE E +++ K ++RR+ + ++E ++ G EL
Sbjct: 151 RHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDL 210
Query: 411 -----SSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPS------ 459
S +ASD S E+ P ++KAP + + K D
Sbjct: 211 EDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQE 270
Query: 460 ---LPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLEVFCEQEEK 504
+ SSSS K E+ K G+D+ + E EE+
Sbjct: 271 VDYMSDGSSSSQEEPESKAKAPQQEEGPK----GVDEQSDSSEESEEE 314
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 47.8 bits (112), Expect = 5e-05
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Query: 17 RSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVA 76
+ +K K K + ++E++ ++EKP K+ + +V + +K P K
Sbjct: 650 KEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEV 709
Query: 77 KVTVKSENLKVIKDEALSDGDDLRDFPSDLKKA----HHLKRGATMNEDSNEEEEESEND 132
K VK E K +K E +++ P D KK+ K+ A + ++EE + D
Sbjct: 710 KKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKD 769
Query: 133 WEEAKTRERSEKIKL 147
A + KIK+
Sbjct: 770 SVAAGKPKEKGKIKV 784
Score = 38.5 bits (88), Expect = 0.028
Identities = 43/215 (20%), Positives = 80/215 (37%), Gaps = 13/215 (6%)
Query: 283 QPIPLKSATAKGKKPSKE-----RLTADPGGSSETSSQV-----LENHTKPK-TSKGTKQ 331
+P+P KS + K+ + E + P S+ V ++ TKP T K
Sbjct: 550 KPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPS 609
Query: 332 EETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRV 391
+E + + K + + + K E P DK+E+ + + ++ + +
Sbjct: 610 KEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPI 669
Query: 392 SYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHR 451
+E+ +E E+ E +P E + PPK+ K + K K + +
Sbjct: 670 KKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK 729
Query: 452 GSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKR 486
+K P A SS+ KK + K K+
Sbjct: 730 KEIKKLPK--DAKKSSTPLSEAKKPAALKPKVPKK 762
Score = 32.3 bits (72), Expect = 2.0
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 4 KRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHP 63
K+ EP+ + K K ++EE+++ ++EK PKK + K+ S P
Sbjct: 689 KKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKS---STP 745
Query: 64 GGSADGPAKKKVAKVTVKSENLK 86
A PA K KV K E++K
Sbjct: 746 LSEAKKPAALK-PKVPKKEESVK 767
Score = 31.2 bits (69), Expect = 4.5
Identities = 31/139 (22%), Positives = 56/139 (40%), Gaps = 27/139 (19%)
Query: 3 RKRAAGGEPRGRE------LRSQKSKAKSKARREEEEEDAFEDEKPPKKS-----LLSKV 51
R+ A G+ R E + + +++ +A E++ EDA E+E P+K +++ V
Sbjct: 990 RESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVV 1049
Query: 52 SQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHH 111
+ G G P K+ A+ + E I DE L G +
Sbjct: 1050 DKAAEAGGAEEQYGFLTTPTKQLGAQ-SPGREPASSIHDETLPGGSESE----------- 1097
Query: 112 LKRGATMNEDSNEEEEESE 130
AT +++ N E++ E
Sbjct: 1098 ----ATASDEENREDQPEE 1112
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 47.4 bits (111), Expect = 6e-05
Identities = 57/218 (26%), Positives = 86/218 (39%), Gaps = 26/218 (11%)
Query: 288 KSATAKGKKPSKERLTADPGGS-SETSSQVLENHT-------KPKTSKGTKQEETFAKGT 339
KS T +K + T D S S ++++ + KP T EE
Sbjct: 430 KSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSI 489
Query: 340 CRPSAKGKRNK--GGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGR-ERRVASRVSYKEE 396
R + G++++ RKK + ++S+E D T+ + G R+V+S+ +
Sbjct: 490 ARENKDGEKSRTVSSRKKPASKATSDEK----DSFSNITRGKKDGEISRKVSSQKPPTLK 545
Query: 397 SGSDEAGS--GSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKA-----GSKSASRT 449
SDE S G E GE S + PG KA + ++ G K +T
Sbjct: 546 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPG----LKASSDEKDSVLNIARGKKYGEKT 601
Query: 450 HRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
R S RK PSL A S S + DGE + K S
Sbjct: 602 KRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVS 639
Score = 45.4 bits (106), Expect = 2e-04
Identities = 59/229 (25%), Positives = 92/229 (40%), Gaps = 32/229 (13%)
Query: 295 KKPSKERLTADPGGSSETSSQVLENHT-------KPKTSKGTKQEETFAKGTCRPSAKGK 347
KKPS E + + S + + + KP KGT EE G R
Sbjct: 608 KKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAR------ 661
Query: 348 RNKGGRKKRSKPSSSEEDEG---PGDKQEK----ATQRRPHGRERRVASRVSYKEESGSD 400
NK G K R+ SSE+ G D+++ A ++ + R V+S+ ++ SD
Sbjct: 662 ENKDGEKSRTV--SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSD 719
Query: 401 EAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKA-----GSKSASRTHRGSHR 455
E S + + SE P KA + ++ G K +T R S R
Sbjct: 720 EEDSVLSIARENKDGEKSRTVSSEK--PSGLKATSAEKDSVLNIARGKKYGEKTKRVSSR 777
Query: 456 KDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQ-WLEVFCEQEE 503
K P+L A S S + DGEK+ R+++ Q L+ C++E+
Sbjct: 778 KKPALKATSDEKDSVLYIAREKKDGEKS--RTVSSQKQPALKAICDKED 824
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 47.4 bits (111), Expect = 6e-05
Identities = 57/218 (26%), Positives = 86/218 (39%), Gaps = 26/218 (11%)
Query: 288 KSATAKGKKPSKERLTADPGGS-SETSSQVLENHT-------KPKTSKGTKQEETFAKGT 339
KS T +K + T D S S ++++ + KP T EE
Sbjct: 430 KSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSI 489
Query: 340 CRPSAKGKRNK--GGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGR-ERRVASRVSYKEE 396
R + G++++ RKK + ++S+E D T+ + G R+V+S+ +
Sbjct: 490 ARENKDGEKSRTVSSRKKPALKATSDEK----DSFSNITRGKKDGEISRKVSSQKPPTLK 545
Query: 397 SGSDEAGS--GSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKA-----GSKSASRT 449
SDE S G E GE S + PG KA + ++ G K +T
Sbjct: 546 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPG----LKASSAEKDSVLNIARGKKDGEKT 601
Query: 450 HRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
R S RK PSL A S S + DGE + K S
Sbjct: 602 KRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVS 639
Score = 36.2 bits (82), Expect = 0.14
Identities = 57/266 (21%), Positives = 97/266 (36%), Gaps = 30/266 (11%)
Query: 295 KKPSKERLTADPGGSSETSSQVLENHT-------KPKTSKGTKQEETFAKGTCRPSAKGK 347
KKPS E + + S + + + KP KGT EE G R + G+
Sbjct: 608 KKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGE 667
Query: 348 RNKGGRKKRS---KPSSSEED------EGPGDKQEKATQRRPHGRERRVASRVSYKEESG 398
+++ ++ K +S E+D G D ++ T P ++ + KE+S
Sbjct: 668 KSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSP---KQPALKAICDKEDSV 724
Query: 399 SDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDP 458
+ A D ++S + K + P K G +S + S +K P
Sbjct: 725 PNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGT----VSSQKQP 780
Query: 459 SLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLEVFCEQ-EEKWVCVDCVHGVVGQ 517
+ A S S DG + R ++ V +Q EEK+ ++ GV Q
Sbjct: 781 AWKATSVKKDSVSNIATEIKDG---QIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQ 837
Query: 518 PLTCYKYATKPMTYVVGID---SDGW 540
+ K K ++ I + GW
Sbjct: 838 KQSAQKVIFKKKVSLLNIATRITGGW 863
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 46.6 bits (109), Expect = 1e-04
Identities = 46/188 (24%), Positives = 69/188 (36%), Gaps = 12/188 (6%)
Query: 299 KERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSA------KGKRNKGG 352
KER D SE+ ++ E K K K +E + + + K ++K
Sbjct: 402 KERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR 461
Query: 353 RKKRSKPSSSEEDEGPGDKQEKATQRRPHGRE-RRVASRVSYKEESGSDEAGSGSDFELS 411
K + K S E D +EK + R GR+ V + + G D+ S S E S
Sbjct: 462 SKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK-EKS 520
Query: 412 SGEASDPSDEDSEPGPPKQRKAPAPQR----TKAGSKSASRTHRGSHRKDPSLPAASSSS 467
S ++ D K R+A + R TK SRT S +D S S +
Sbjct: 521 KQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTH 580
Query: 468 SSSKRGKK 475
+ K
Sbjct: 581 DRDRSRSK 588
Score = 37.4 bits (85), Expect = 0.063
Identities = 48/215 (22%), Positives = 88/215 (40%), Gaps = 30/215 (13%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
KS+++ S ++D SS++S E+ T+ K+ K K+ + S K K
Sbjct: 192 KSSSSSSSSSSDSDSSSDSQSSSDSSDS--ESATEEKSKKRKKKHR-------KNSRKHK 242
Query: 348 RNKGGRKKRSKPSSSEEDEGPGDKQEKATQRR---PHGRERRVASRVSYKEESGSDEAGS 404
+ K RKK K +SSE + + Q ++T R P E R R K +DE
Sbjct: 243 KEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMR---KSPPKADE--- 296
Query: 405 GSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQR---TKAGSKSASRTHRGSHRKDPSLP 461
+ + + E PP + A +R T++G K R R + PS
Sbjct: 297 -------KERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPR--RYRTPSRS 347
Query: 462 AASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLE 496
+ S+ + ++A++ ++ ++W++
Sbjct: 348 RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIK 382
Score = 36.6 bits (83), Expect = 0.11
Identities = 53/221 (23%), Positives = 84/221 (38%), Gaps = 38/221 (17%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPS-AKG 346
K A +K + SKE+ S E S+ N K S+ ++ K + S +KG
Sbjct: 454 KRAKSKSRSKSKEK-----SKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKG 508
Query: 347 KRNKGGR-KKRSKPSSSEEDEGPGDKQEKATQR-------------------------RP 380
K + R K++SK S+ +E K ++ +R R
Sbjct: 509 KDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRS 568
Query: 381 HGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTK 440
R RRV SR ++ S S E + E S + + PG + + +R +
Sbjct: 569 RDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDR---RRRR 625
Query: 441 AGSKSASRTHRGSHRKDPSLPAASSSS---SSSKRGKKMCS 478
S+S+ R S KD S SS +S+ K+M S
Sbjct: 626 RDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYS 666
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 9/103 (8%)
Query: 789 ENEQAVIERKEKEKKEKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTDAGGGLSSD 848
E E + K E R L +L+ K + +E KR S +++ SSD
Sbjct: 153 EIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSS---------SSD 203
Query: 849 EEEGTSSQAEAARILAASWPQNREDEEKQKLKGGPKKTKREKK 891
+ + SQ+ + + S + + + K+K + +K K+EKK
Sbjct: 204 SDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKK 246
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 46.2 bits (108), Expect = 1e-04
Identities = 46/198 (23%), Positives = 72/198 (36%), Gaps = 17/198 (8%)
Query: 290 ATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRN 349
A + G KP + SS +SS + + K +G K E P +G++
Sbjct: 238 ADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPL-----PKPRGRKP 292
Query: 350 KGGRKKRSKPSSSEEDE----------GPGDKQEKATQRRPHGRE--RRVASRVSYKEES 397
K R S S S+ DE ++E +RR E RR+ + ++E
Sbjct: 293 KPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352
Query: 398 GSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKD 457
+ A G S G + D ED EP + RK + +K
Sbjct: 353 RRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKS 412
Query: 458 PSLPAASSSSSSSKRGKK 475
P +SS+ + K G+K
Sbjct: 413 AKKPQSSSTEPARKPGQK 430
Score = 41.2 bits (95), Expect = 0.004
Identities = 78/405 (19%), Positives = 147/405 (36%), Gaps = 65/405 (16%)
Query: 12 RGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPA 71
R E R ++ +A+ + +EEE E EK K+ + +G+ +RG GGS+
Sbjct: 318 RRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERG---SGGSSGDEL 374
Query: 72 KKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKA---------HHLKRGATMNEDS 122
++ V + + + SD + + + KK+ ++ +
Sbjct: 375 REDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRV 434
Query: 123 NEEEEESENDWEEAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFY 182
EE++ + +TR+RSE ++ R+ K+ V E K+H A
Sbjct: 435 RPEEKQQAKPVKVERTRKRSEGFSMD-----RKVEKKKEPSVEEKLQKLHSEIKFALK-- 487
Query: 183 RNNICSQPDLHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQDNL 242
PD+ R L +GT V +++ D +
Sbjct: 488 ----VDSPDV---------KRCLNALEE--------------LGTLQVTSQILQKNTDVV 520
Query: 243 QTTLERRFAIYSARDDEELVHIFLLILRALQLLTRL---VL--SLQPIPLKSATAKGKKP 297
T ++ Y A D ++ +A ++ TRL VL ++ + + K+
Sbjct: 521 ATL--KKIRRYKANKD--------VMEKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEK 570
Query: 298 SKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRS 357
++E+L + E + E+ S E T KG SA+ K ++ GR
Sbjct: 571 AEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKG---ESAEDKEHEEGRDSEE 627
Query: 358 KPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEA 402
P ++ +E RP G +R+ R E+ +E+
Sbjct: 628 GPRCGSSEDLHDSVREGPDLDRP-GSDRQERERARGDSEALDEES 671
Score = 38.9 bits (89), Expect = 0.022
Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 24/162 (14%)
Query: 289 SATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKR 348
S + + +K S + A S E +S+ K T ++ K R +G
Sbjct: 165 SVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEK----KAAVRAPRRGPL 220
Query: 349 NKGGRKKRSKPSSSEED---EGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSG 405
GGRKK+ PS+S+ D + G K E R S S + S
Sbjct: 221 --GGRKKKKAPSASDSDSKADSDGAKPEPVAMAR---------------SASSSSSSSSS 263
Query: 406 SDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSAS 447
SD ++S + +P P + + P P+R + S S S
Sbjct: 264 SDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDS 305
Score = 33.1 bits (74), Expect = 1.2
Identities = 38/148 (25%), Positives = 57/148 (38%), Gaps = 20/148 (13%)
Query: 353 RKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSS 412
R + S D ++ A + R R+ +S + S S+E S S S
Sbjct: 139 RMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSES-----S 193
Query: 413 GEASDPSDEDSEPGPPKQRKAPAPQRTKAG----------SKSASRTHRGSHRKDPSLPA 462
E+ SD+D P K+ AP+R G S S S+ + +P A
Sbjct: 194 SESEKTSDQDFTP--EKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMA 251
Query: 463 ASSSSSSSKRGKKMCSDGEKAEKRSIAG 490
S+SSSSS SD + + K+ G
Sbjct: 252 RSASSSSSSSSS---SDSDVSVKKPPRG 276
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 46.2 bits (108), Expect = 1e-04
Identities = 46/200 (23%), Positives = 76/200 (38%), Gaps = 26/200 (13%)
Query: 287 LKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKG 346
L + K K+PS + T+ + + +P K +K+E+ K R ++
Sbjct: 223 LPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS 282
Query: 347 K-----------RNKGGRKKRSKPSSSEEDEGPGDKQEKATQRR-------PHGRERRVA 388
K + R+ RS+ S P ++ + +RR P R RR
Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR 342
Query: 389 SRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASR 448
S V + S + +GS S +S S S P P +R + P++T+ S SAS
Sbjct: 343 SPVRRRRRSSASLSGSSS--------SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASP 394
Query: 449 THRGSHRKDPSLPAASSSSS 468
R P+ P + S
Sbjct: 395 PRRRHRPSPPATPPPKTRHS 414
Score = 37.7 bits (86), Expect = 0.049
Identities = 39/192 (20%), Positives = 66/192 (34%), Gaps = 7/192 (3%)
Query: 303 TADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRN----KGGRKKRSK 358
++ GSS +S + K + ++ + PS + ++ +G R++
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS 551
Query: 359 PSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDP 418
P + P +R P RR + S S S S
Sbjct: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK 611
Query: 419 SDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGS---HRKDPSLPAASSSSSSSKRGKK 475
S P PPK+R +P+P + S S R S R+ PSL + SS R +
Sbjct: 612 RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTR 671
Query: 476 MCSDGEKAEKRS 487
+ ++ S
Sbjct: 672 EARSPQPNKRHS 683
Score = 35.8 bits (81), Expect = 0.18
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 5/136 (3%)
Query: 345 KGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRP--HGRERRVASRVSYKEESGSD-E 401
K +R++ R+++S+ S P ++ K + R H + R S K+E +
Sbjct: 165 KRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
Query: 402 AGSGSDFELSSGEASDPSD--EDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPS 459
S E S EA+ SD + +P P + K P+P++ K +T S + S
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
Query: 460 LPAASSSSSSSKRGKK 475
S S S R ++
Sbjct: 285 RSRTRSRSPSHTRPRR 300
Score = 35.0 bits (79), Expect = 0.32
Identities = 49/190 (25%), Positives = 67/190 (35%), Gaps = 26/190 (13%)
Query: 286 PLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAK 345
P K TA P K R + P S H+ P KQ + PS
Sbjct: 609 PPKRRTASPPPPPKRRASPSPPPKRRVS------HSPPP-----KQRSSPVTKRRSPSLS 657
Query: 346 GKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSG 405
K KG RS + E P + + RP A + S A S
Sbjct: 658 SKHRKGSSPSRS----TREARSPQPNKRHSPSPRPR------APQTSSSPPPVRRGASSS 707
Query: 406 SDFELSSGEASDPSDEDSE-PGPPKQRKA--PAPQ--RTKAGSKSASRTHRGSHRKDPSL 460
S ++ P S P P K +KA P+PQ R + S+S S + + +K P+
Sbjct: 708 PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP 767
Query: 461 PAASSSSSSS 470
P+ S S S
Sbjct: 768 PSPVQSQSPS 777
Score = 33.1 bits (74), Expect = 1.2
Identities = 43/189 (22%), Positives = 68/189 (35%), Gaps = 18/189 (9%)
Query: 299 KERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSK 358
KE + + +S ++ K K K K+ + R + K ++RS
Sbjct: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSS 187
Query: 359 PSSSEEDEGPGDKQEKATQRR-----PHGRERRVA---SRVSYKEESGSDEAGSGSDFEL 410
P E T+ R P +E+ V KE S EA S SD +
Sbjct: 188 PVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS-VQEATSTSD--I 244
Query: 411 SSGEASDPSDEDSEPGPPKQRKAPAPQ-------RTKAGSKSASRTHRGSHRKDPSLPAA 463
+P E EP P K K + R+++ S+S +R+ SH + +
Sbjct: 245 LKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRS 304
Query: 464 SSSSSSSKR 472
S S S +R
Sbjct: 305 RSRSYSPRR 313
Score = 32.7 bits (73), Expect = 1.6
Identities = 47/211 (22%), Positives = 73/211 (34%), Gaps = 11/211 (5%)
Query: 284 PIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTK-QEETFAKGTCRP 342
P P A P K R++ P + SS V + + +SK K + + R
Sbjct: 617 PPPPPKRRASPSPPPKRRVSHSPP-PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS 675
Query: 343 SAKGKRNKGGRKKRSKPSSSEED---EGPGDKQEKATQRRPHGRERRVASRVSYKEESGS 399
KR+ + R+ +SS G ++ P R R SR E
Sbjct: 676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTP--EPKKI 733
Query: 400 DEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRT----HRGSHR 455
+A S S + +S EP K P+P ++++ S + S S
Sbjct: 734 KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPT 793
Query: 456 KDPSLPAASSSSSSSKRGKKMCSDGEKAEKR 486
PS P S K+ KK K +K+
Sbjct: 794 PSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824
Score = 31.2 bits (69), Expect = 4.5
Identities = 45/229 (19%), Positives = 71/229 (31%), Gaps = 26/229 (11%)
Query: 284 PIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPS 343
P P + ++ + R +A GSS +SS K K T + PS
Sbjct: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR-RLSPS 391
Query: 344 AKGKRNK---------------------GGRKKRSKPSSSEEDEGPGDKQEKATQRR--- 379
A R + R ++S+ S S + K T++R
Sbjct: 392 ASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP 451
Query: 380 -PHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQR 438
P + R+V S +++ G A + S DS + + P
Sbjct: 452 SPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSH 511
Query: 439 TKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
K G R H S PS +S R ++ S +RS
Sbjct: 512 VKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 46.2 bits (108), Expect = 1e-04
Identities = 46/198 (23%), Positives = 72/198 (36%), Gaps = 17/198 (8%)
Query: 290 ATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRN 349
A + G KP + SS +SS + + K +G K E P +G++
Sbjct: 238 ADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPL-----PKPRGRKP 292
Query: 350 KGGRKKRSKPSSSEEDE----------GPGDKQEKATQRRPHGRE--RRVASRVSYKEES 397
K R S S S+ DE ++E +RR E RR+ + ++E
Sbjct: 293 KPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352
Query: 398 GSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKD 457
+ A G S G + D ED EP + RK + +K
Sbjct: 353 RRERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKS 412
Query: 458 PSLPAASSSSSSSKRGKK 475
P +SS+ + K G+K
Sbjct: 413 AKKPQSSSTEPARKPGQK 430
Score = 40.4 bits (93), Expect = 0.007
Identities = 80/393 (20%), Positives = 143/393 (36%), Gaps = 76/393 (19%)
Query: 12 RGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPA 71
R E R ++ +A+ + +EEE E EK K+ + +G+ +RG GGS+
Sbjct: 318 RRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERG---SGGSSGDEL 374
Query: 72 KKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKA---------HHLKRGATMNEDS 122
++ V + + + SD + + + KK+ ++ +
Sbjct: 375 REDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARKPGQKEKRV 434
Query: 123 NEEEEESENDWEEAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFY 182
EE++ + +TR+RSE ++ R+ K+ V E K+H A
Sbjct: 435 RPEEKQQAKPVKVERTRKRSEGFSMD-----RKVEKKKEPSVEEKLQKLHSEIKFALK-- 487
Query: 183 RNNICSQPDLHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQDNL 242
PD+ R L +GT V +++ D +
Sbjct: 488 ----VDSPDV---------KRCLNALEE--------------LGTLQVTSQILQKNTDVV 520
Query: 243 QTTLERRFAIYSARDDEELVHIFLLILRALQLLTRL---VL--SLQPIPLKSATAKGKKP 297
T ++ Y A D ++ +A ++ TRL VL ++ + + K+
Sbjct: 521 ATL--KKIRRYKANKD--------VMEKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEK 570
Query: 298 SKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRS 357
++E+L + E + E+ S E T KG SA+ K ++ GR
Sbjct: 571 AEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKG---ESAEDKEHEEGRDSEE 627
Query: 358 KP-SSSEED-----EGP------GDKQEKATQR 378
P S ED EGP D+QE+ R
Sbjct: 628 GPRCGSSEDLHDVREGPDLDRPGSDRQERERAR 660
Score = 38.9 bits (89), Expect = 0.022
Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 24/162 (14%)
Query: 289 SATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKR 348
S + + +K S + A S E +S+ K T ++ K R +G
Sbjct: 165 SVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPEK----KAAVRAPRRGPL 220
Query: 349 NKGGRKKRSKPSSSEED---EGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSG 405
GGRKK+ PS+S+ D + G K E R S S + S
Sbjct: 221 --GGRKKKKAPSASDSDSKADSDGAKPEPVAMAR---------------SASSSSSSSSS 263
Query: 406 SDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSAS 447
SD ++S + +P P + + P P+R + S S S
Sbjct: 264 SDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSDS 305
Score = 33.1 bits (74), Expect = 1.2
Identities = 38/148 (25%), Positives = 57/148 (38%), Gaps = 20/148 (13%)
Query: 353 RKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSS 412
R + S D ++ A + R R+ +S + S S+E S S S
Sbjct: 139 RMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSES-----S 193
Query: 413 GEASDPSDEDSEPGPPKQRKAPAPQRTKAG----------SKSASRTHRGSHRKDPSLPA 462
E+ SD+D P K+ AP+R G S S S+ + +P A
Sbjct: 194 SESEKTSDQDFTP--EKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMA 251
Query: 463 ASSSSSSSKRGKKMCSDGEKAEKRSIAG 490
S+SSSSS SD + + K+ G
Sbjct: 252 RSASSSSSSSSS---SDSDVSVKKPPRG 276
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/240 (22%), Positives = 97/240 (40%), Gaps = 8/240 (3%)
Query: 237 SEQDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLT--RLVLSLQPIPLKSATAKG 294
SE++ + T+E+ A + IF +I + ++ L R ++ L+ + +
Sbjct: 1523 SEEEEVVVTIEKPPAAEPTYTTWKRARIFPMIFKKVRGLADKRGIVDLEGEEWQRRLEEE 1582
Query: 295 KKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRK 354
K +LT D ++E++ + E + T ++ E T ++ + +
Sbjct: 1583 DKDYL-KLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPS--EE 1639
Query: 355 KRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGE 414
+ S SEE E + EKA + R R + V KE G E E E
Sbjct: 1640 EESSTPESEESESTESEGEKARKNIVLARRRPMVEEV--KEVKGRKEEPQEEQKEPKMEE 1697
Query: 415 ASDPSDEDSEPGPPKQRKAPAPQR-TKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRG 473
+E+S P P ++ P Q + GS ++ G ++ S +SSSSS S+ G
Sbjct: 1698 EEHSEEEESGPAPVEESTDPEAQDIPEEGSAESASVEGGVESEEESESGSSSSSSESQSG 1757
Score = 39.7 bits (91), Expect = 0.013
Identities = 43/165 (26%), Positives = 63/165 (38%), Gaps = 26/165 (15%)
Query: 300 ERLTADPGGSSETSSQVLENHT------KPKTSKGTKQEETFAKGTCRPSAKGKRNKGGR 353
E T + SET S+ E+ T + S+G K + RP + + GR
Sbjct: 1623 ESETTEEESESETPSEEEESSTPESEESESTESEGEKARKNIVLARRRPMVEEVKEVKGR 1682
Query: 354 KKRSKPS-----------SSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEA 402
K+ + S EE+ GP +E E A ES S E
Sbjct: 1683 KEEPQEEQKEPKMEEEEHSEEEESGPAPVEESTDPEAQDIPEEGSA-------ESASVEG 1735
Query: 403 GSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSAS 447
G S+ E SG +S S +S+ G P + PA R+K ++ S
Sbjct: 1736 GVESEEESESGSSS--SSSESQSGGPWGYQVPAYDRSKNANQKKS 1778
Score = 38.5 bits (88), Expect = 0.028
Identities = 34/163 (20%), Positives = 70/163 (42%), Gaps = 10/163 (6%)
Query: 310 SETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPG 369
SET+ + E+ T + + + E ++ T K ++N ++R P E E G
Sbjct: 1624 SETTEEESESETPSEEEESSTPESEESESTESEGEKARKNIVLARRR--PMVEEVKEVKG 1681
Query: 370 DKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPK 429
K+E +E + ++ +E S +E+G E + EA D +E S
Sbjct: 1682 RKEEP--------QEEQKEPKMEEEEHSEEEESGPAPVEESTDPEAQDIPEEGSAESASV 1733
Query: 430 QRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKR 472
+ + + +++GS S+S + +PA S +++++
Sbjct: 1734 EGGVESEEESESGSSSSSSESQSGGPWGYQVPAYDRSKNANQK 1776
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 45.8 bits (107), Expect = 2e-04
Identities = 50/210 (23%), Positives = 80/210 (38%), Gaps = 23/210 (10%)
Query: 296 KPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKK 355
+P+KER ++ SS +SS + + +S G+ ++ +G+ P K
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS--EGSSLPVQPEVALKRVPSP 2582
Query: 356 RSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEA 415
P + + P + +RR +S S S S + S S SS +
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Query: 416 SDPSDEDS--EPGP---PKQ---RKAPAPQRTKAG----------SKSASRTHRGSHRKD 457
S S S +PGP PK +K P +R S+S S + R
Sbjct: 2643 SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPS 2702
Query: 458 PSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
P SSSS+RG + G++ + RS
Sbjct: 2703 PQPSPRDQQSSSSERGSRR---GQRGDSRS 2729
Score = 42.0 bits (97), Expect = 0.003
Identities = 56/250 (22%), Positives = 95/250 (38%), Gaps = 31/250 (12%)
Query: 257 DDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQ- 315
D E + L L +++ Q I K AT + K+ +PGG ET Q
Sbjct: 59 DHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD---VNPGGKEETPGQR 115
Query: 316 --VLENHTKPKTSKGTKQEETFAKG---------TCRPSAKGKRNKGGRKKRSKPSS--- 361
V E H + ++ + A G + P + + K + KP S
Sbjct: 116 PAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVR 175
Query: 362 -SEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSD 420
S P KQ+K +++ GR +S +++S + E+
Sbjct: 176 ESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK--------HRSESESKKR 227
Query: 421 EDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDG 480
+ P P +RK+ +R ++ S + + R +HR S +ASSS +S R + S
Sbjct: 228 KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHR-STSADSASSSDTSRSRSR---SAA 283
Query: 481 EKAEKRSIAG 490
K ++AG
Sbjct: 284 AKTHTTALAG 293
Score = 41.2 bits (95), Expect = 0.004
Identities = 48/185 (25%), Positives = 65/185 (35%), Gaps = 18/185 (9%)
Query: 293 KGKKPSKERLTADPGGS-SETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKG 351
+ + S + L P S E S +K KT +Q ++ P K
Sbjct: 1536 RSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQR---SRSGSSPEVDSKSRLS 1592
Query: 352 GRKKRSKPSSSEEDE---GPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDF 408
R+ RS S +D+ P + + P R R + SGS G G
Sbjct: 1593 PRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPR---RSRSGSSSKGRGPSP 1649
Query: 409 ELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRT--HRGSHRKDPSLPAASSS 466
E SS S P PPK R A R+ K+ SRT R S R P L +
Sbjct: 1650 EGSSSTESSPEH------PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 467 SSSSK 471
S S+
Sbjct: 1704 SRRSR 1708
Score = 40.8 bits (94), Expect = 0.006
Identities = 49/201 (24%), Positives = 77/201 (38%), Gaps = 12/201 (5%)
Query: 290 ATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSK-GTKQEETFAKGTCRPSAKGKR 348
++ + K S+ L GSS Q ++ T P+ S+ G+ Q + ++ R S
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCPKQ--KSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS 820
Query: 349 NKGGRKKRSKPSSSEEDEGPGDKQEKATQRR------PHGRERRVA-SRVSYKEESGSDE 401
+K ++ S P K + T R P E+ V R S E S E
Sbjct: 821 PPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE 880
Query: 402 AGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQ-RTKAGSKSASRTHRGSHRKDPSL 460
S + S +S P + S P ++ +PQ + KA R+H GS PS
Sbjct: 881 LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS- 939
Query: 461 PAASSSSSSSKRGKKMCSDGE 481
S ++ R CS+ E
Sbjct: 940 RVTSRTTPRRSRSVSPCSNVE 960
Score = 40.0 bits (92), Expect = 0.010
Identities = 50/227 (22%), Positives = 85/227 (37%), Gaps = 21/227 (9%)
Query: 273 QLLTRLVLSLQPI--PLKSATAKGKKPSK--ERLTADPGGSSETSSQVLENHTK------ 322
Q L LS +P+ P +++ + + P K E+L P SS SS TK
Sbjct: 379 QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL---PQSSSSESSPPSPQPTKVSRHAS 435
Query: 323 --PKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRP 380
P++ K + + + P++K + + GR KR K S G + AT +R
Sbjct: 436 SSPESPKPAPAPGSHREISSSPTSKNRSH--GRAKRDKSHSHTPSRRMGRSRSPATAKRG 493
Query: 381 HGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTK 440
R R R + S + G + P P + + + +
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQ---RWGRSRSPQRRGRSRSPQRPGWSRSRNTQR 550
Query: 441 AGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
G ++R R SH + P+ S S + ++RG+ + RS
Sbjct: 551 RGRSRSARRGR-SHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRS 596
Score = 39.7 bits (91), Expect = 0.013
Identities = 36/146 (24%), Positives = 50/146 (34%), Gaps = 23/146 (15%)
Query: 363 EEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASD----- 417
E G +Q A +ERR +S S S S + S S S +SD
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
Query: 418 ------------------PSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPS 459
P + E PP+ A +R+ + S S+S + S S
Sbjct: 2568 LPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS 2627
Query: 460 LPAASSSSSSSKRGKKMCSDGEKAEK 485
++SSSSSSS S K
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAK 2653
Score = 38.5 bits (88), Expect = 0.028
Identities = 50/207 (24%), Positives = 78/207 (37%), Gaps = 26/207 (12%)
Query: 286 PLKSATAKGKKPSKERLTADPGGSSET-SSQVLENHTKPKTSKGTKQEETFAKGTCRPSA 344
P + + P + L P S + SS L N + + E + + T +
Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP 1532
Query: 345 KGKRNKGGRKKRS--KPSSSEEDEGPGDKQ--EKATQRRPHGRERRVASRVSYKEESGSD 400
G+R++ G + KPS+S ++ D KA R P + R
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSR-------------- 1578
Query: 401 EAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSL 460
SGS E+ S P S P + K A R ++GS S+ + R +L
Sbjct: 1579 ---SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR---AL 1632
Query: 461 PAASSSSSSSKRGKKMCSDGEKAEKRS 487
P S S SSSK G+ +G + + S
Sbjct: 1633 PRRSRSGSSSK-GRGPSPEGSSSTESS 1658
Score = 37.7 bits (86), Expect = 0.049
Identities = 42/222 (18%), Positives = 80/222 (36%), Gaps = 17/222 (7%)
Query: 290 ATAKGKKPSKERLTADPGG-----SSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSA 344
+++KG+ PS E ++ S T+ + + +PKT T ++ + +
Sbjct: 1640 SSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTR 1699
Query: 345 KGKRNKGGRKKRSKPSSSEED-----EGPGDKQEKATQRRPHGRERRVASRVSYKEESGS 399
K + ++ R S P + P + ++ R RR AS K S
Sbjct: 1700 KARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRR 1759
Query: 400 DEAGSGSDFELSSGEASDPSDEDS-----EPGPPKQRKAPAPQRTKAGSKSASRTHRGS- 453
+ S L + ++ + Q + QR+++ S+ R GS
Sbjct: 1760 GRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819
Query: 454 -HRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQW 494
H + P+ +S +SS +RG+ + RS W
Sbjct: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPW 1861
Score = 37.4 bits (85), Expect = 0.063
Identities = 36/162 (22%), Positives = 57/162 (35%), Gaps = 11/162 (6%)
Query: 322 KPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPH 381
+P S G +Q A AK +R+ S SSS ++
Sbjct: 2508 EPPASTGAQQPSALA---ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 382 GRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKA 441
G V V+ K A + + G +P+ P K+R + + + +
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEA---VREGRPPEPT-----PAKRKRRSSSSSSSSSS 2616
Query: 442 GSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKA 483
S S+S + S S ++SSSSSSS G +A
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658
Score = 33.5 bits (75), Expect = 0.92
Identities = 42/178 (23%), Positives = 64/178 (35%), Gaps = 9/178 (5%)
Query: 298 SKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAK-GTCRPSAKGKRNKGGRKKR 356
S+ R T G S S++ +H++ ++G + T A+ G R +R R
Sbjct: 543 SRSRNTQRRGRSR--SARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPT 600
Query: 357 SKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEAS 416
+ S S G ++ R P R R S V + S S SG S A
Sbjct: 601 RRRSRSRTPARRG----RSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRS--RSRTPAR 654
Query: 417 DPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGK 474
P + ++ P R S+S + RG R S S S +RG+
Sbjct: 655 RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGR 712
Score = 33.1 bits (74), Expect = 1.2
Identities = 39/214 (18%), Positives = 78/214 (36%), Gaps = 24/214 (11%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKG--TKQEETFAKGTCRPSAK 345
+S T + S+ R A G S + + ++ +T + ++ +G
Sbjct: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP 718
Query: 346 GKRNKGG----RKKRSKPSS--SEEDEGPGDKQEKATQRRPHGRER---RVASRVSYKEE 396
+R + G RK +S+ S S + P K+ + + RR + SR+S +
Sbjct: 719 QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRS 778
Query: 397 -SGSD------------EAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGS 443
SGS + SGS + S PPKQ+ +++ + S
Sbjct: 779 LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSS 838
Query: 444 KSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMC 477
+ G+ + S+ + ++ S ++ C
Sbjct: 839 SPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC 872
Score = 32.0 bits (71), Expect = 2.7
Identities = 37/192 (19%), Positives = 68/192 (35%), Gaps = 7/192 (3%)
Query: 284 PIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPS 343
P T+ + S E T P E + + + + S ++ T +
Sbjct: 309 PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368
Query: 344 AKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAG 403
+R+ G + + S+E P + R P ++ S + S +
Sbjct: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPT 428
Query: 404 SGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPS-LPA 462
S SS E+ P+ P P R+ + +K S ++ + SH PS
Sbjct: 429 KVSRHASSSPESPKPA-----PAPGSHREISSSPTSKNRSHGRAKRDK-SHSHTPSRRMG 482
Query: 463 ASSSSSSSKRGK 474
S S +++KRG+
Sbjct: 483 RSRSPATAKRGR 494
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 45.4 bits (106), Expect = 2e-04
Identities = 63/248 (25%), Positives = 94/248 (37%), Gaps = 56/248 (22%)
Query: 280 LSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGT 339
++L+ L+S + KG P P SS+ +P T+ K AK
Sbjct: 256 MALKETKLESTSPKGGPPPPP--PPPPRASSK----------RPATADSPKPS---AKKQ 300
Query: 340 CRPSAKGKRNKGGRKKRSKPSSSEEDEGPG-DKQEKATQRRPHGRERRVASRVSYKEESG 398
+ S+KG R+ G R+ SSS D+ P DK ++ E R A + EES
Sbjct: 301 KKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESN 360
Query: 399 S-DEAGSGSDFELSSGEASDPSDEDSEPG--PPKQRKAPAPQR---------------TK 440
S DEA S+ SS S S + S P Q + P R +
Sbjct: 361 SEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSS 420
Query: 441 AGSKSASRTHRG------------SHRKDPSLPAAS----------SSSSSSKRGKKMCS 478
+G ++A +T+ G + D SLP+ +S S +R + CS
Sbjct: 421 SGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCS 480
Query: 479 DGEKAEKR 486
EK K+
Sbjct: 481 KPEKILKK 488
Score = 45.1 bits (105), Expect = 3e-04
Identities = 48/188 (25%), Positives = 77/188 (40%), Gaps = 19/188 (10%)
Query: 322 KPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKP-SSSEEDEGPGDKQEKATQRR- 379
K K S G+K + T +P K ++ +K S+ SSS+E E K K T R+
Sbjct: 174 KTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKL 233
Query: 380 PHGR----ERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPA 435
GR E+ + ++KE A + E +S + P P +R A A
Sbjct: 234 GEGRLPKEEKAPPPKAAFKEPK---MALKETKLESTSPKGGPPPPPPPPPRASSKRPATA 290
Query: 436 PQRTKAGSKSASRTHRGSHRKDPSLPAASSSSS----------SSKRGKKMCSDGEKAEK 485
+ K + +GS + P SSSSS SS RG+K+ ++ E E
Sbjct: 291 DSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREA 350
Query: 486 RSIAGIDQ 493
+ +++
Sbjct: 351 KKALEVEE 358
>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
sapiens]
Length = 1447
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/189 (21%), Positives = 74/189 (39%), Gaps = 19/189 (10%)
Query: 275 LTRLVLSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLEN----HTKPKTSKGTK 330
LT+LV +P + + +G S+ P +LEN ++ PK K +
Sbjct: 1234 LTKLVQEQKPKGSQRSRKRGHTASESDEQQWPE-EKRLKEDILENEDEQNSPPKKGKRGR 1292
Query: 331 QEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASR 390
+ GT + K +K G KK+S P + EE+E ++Q T+++ ++ RV+ R
Sbjct: 1293 PPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEE-EEERQSGNTEQKSKSKQHRVSRR 1351
Query: 391 VSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTH 450
+ ES A + + + G + K P+P + K +
Sbjct: 1352 AQQRAES-------------PESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQ 1398
Query: 451 RGSHRKDPS 459
+ D S
Sbjct: 1399 AATKENDSS 1407
Score = 38.1 bits (87), Expect = 0.037
Identities = 44/179 (24%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 309 SSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGP 368
SSE E++T G K ++ R + R GRKK + + EE G
Sbjct: 1176 SSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPR---GRKK-TPVTEQEEKLGM 1231
Query: 369 GDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPP 428
D + +++P G +R SR S SDE + L + ED + PP
Sbjct: 1232 DDLTKLVQEQKPKGSQR---SRKRGHTASESDEQQWPEEKRLKEDILEN---EDEQNSPP 1285
Query: 429 KQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
K+ K P + G G+ +++P++ S S K G + E+ E++S
Sbjct: 1286 KKGKRGRPPKPLGG---------GTPKEEPTM-KTSKKGSKKKSGPPAPEEEEEEERQS 1334
Score = 37.7 bits (86), Expect = 0.049
Identities = 38/178 (21%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 304 ADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSK-PSSS 362
+D S+ LE K + T+QEE + ++ KG ++ R + ++S
Sbjct: 1198 SDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTAS 1257
Query: 363 EEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDP-SDE 421
E DE ++++ + + + + K G G+ E + + S S +
Sbjct: 1258 ESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKK 1317
Query: 422 DSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHR-----KDPSLPAASSSSSSSKRGK 474
S P P++ + Q KS S+ HR S R + P A S+ S+ ++G+
Sbjct: 1318 KSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGR 1375
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 45.4 bits (106), Expect = 2e-04
Identities = 58/239 (24%), Positives = 82/239 (34%), Gaps = 33/239 (13%)
Query: 281 SLQPIPLKSATAKGKKPSKERLTADPGGSS------ETSSQVLENH---TKPKTSK---- 327
SL P PL + A KP K R + G E V +H T PK+ K
Sbjct: 2421 SLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEA 2480
Query: 328 ----------GTKQEETF--------AKGTCRPSAKG-KRNKGGRKKRSKPSSSEEDEGP 368
G ++ ++ A G+ P A K G + P + ED G
Sbjct: 2481 LLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGN 2540
Query: 369 GDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPP 428
+KA Q G E +S S S S + S S E E D + +
Sbjct: 2541 PKSPDKA-QAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
Query: 429 KQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
+ A + + S S+S + S S ++SSSSSSS S + S
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
Score = 43.9 bits (102), Expect = 7e-04
Identities = 58/213 (27%), Positives = 84/213 (39%), Gaps = 35/213 (16%)
Query: 283 QPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRP 342
QP P A P P S + + T+PK K EE+ AKG RP
Sbjct: 2395 QPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRP 2454
Query: 343 SAKGK-----RNKGGRKKRSKPSSS----EEDEGPGDKQEKATQRRPHGRERRVASRVSY 393
+ + ++G +SK + ED G G QE + + S SY
Sbjct: 2455 GEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQE----------PKSLLSLGSY 2504
Query: 394 KEESGSDEAGS----GSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRT 449
+GS E + +D +L+ + EDS P KA A Q S+S+S +
Sbjct: 2505 PPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDS-GNPKSPDKAQAEQDGAEESESSSSS 2563
Query: 450 HRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEK 482
GS +SSSSSSS G + ++GE+
Sbjct: 2564 SSGS---------SSSSSSSSSSGSE--TEGEE 2585
Score = 43.9 bits (102), Expect = 7e-04
Identities = 41/183 (22%), Positives = 62/183 (33%), Gaps = 16/183 (8%)
Query: 295 KKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRK 354
K P K + D SE+SS + +S + ET + + G GGR
Sbjct: 2542 KSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN 2601
Query: 355 ------KRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDF 408
+ + P+SS ++ +S S S S + S S
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
Query: 409 ELSSGEASD---------PSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPS 459
SS +S SD+++ P P A A TKA +K A + +H
Sbjct: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA-TKQAGKARPSAHSPGKK 2720
Query: 460 LPA 462
PA
Sbjct: 2721 TPA 2723
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/216 (23%), Positives = 78/216 (36%), Gaps = 25/216 (11%)
Query: 279 VLSLQPIPLKSATAKGKKPSKER----LTADPGGSSETSSQVLENHTKPKTSKGTKQEET 334
+LSL P + +++ K P + L +PG E+ PK+ + E+
Sbjct: 2498 LLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPG-----PGLTFEDSGNPKSPDKAQAEQD 2552
Query: 335 FAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYK 394
A+ + S+ + S S E E GDK GR AS +
Sbjct: 2553 GAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTG-GRNCSAASSRAAS 2611
Query: 395 EESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSH 454
S S + S S SS +S S S + + S S+S + S
Sbjct: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSS---------------SSSSSSSSSSSSSSSS 2656
Query: 455 RKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAG 490
S ++SSSSSS+ CS ++A AG
Sbjct: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAG 2692
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 45.1 bits (105), Expect = 3e-04
Identities = 45/165 (27%), Positives = 67/165 (40%), Gaps = 15/165 (9%)
Query: 329 TKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVA 388
T ++ A G PS G++ G R ++++ SS QE R H RR
Sbjct: 3716 THEQSESAHGRAGPSTGGRQ--GSRHEQARDSSRHSAS-----QEGQDTIRGHPGSRRGG 3768
Query: 389 SRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASR 448
+ SY E+S SGS ++ + D+ G R A R + S SR
Sbjct: 3769 RQGSYHEQSVDRSGHSGSHHSHTTSQGR----SDASHGQSGSRSASRETRNEEQSGDGSR 3824
Query: 449 THRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQ 493
H GS + S A SS S S +G+ S G + +R + + Q
Sbjct: 3825 -HSGSRHHEASTQADSSRHSQSGQGE---SAGSRRSRRQGSSVSQ 3865
Score = 40.0 bits (92), Expect = 0.010
Identities = 53/196 (27%), Positives = 75/196 (38%), Gaps = 24/196 (12%)
Query: 299 KERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSK 358
KE G SS S L + + S+ T G PS G++ G R ++++
Sbjct: 1424 KESARGQSGESSGRSRSFLYQVSSHEQSESTH-------GQTAPSTGGRQ--GSRHEQAR 1474
Query: 359 PSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEA-SD 417
SS Q+ R H R + SY E+S SG ++ + SD
Sbjct: 1475 NSSRHSAS-----QDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSD 1529
Query: 418 PSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMC 477
S S P R A R + S SR H GS +PS A SS S +G+
Sbjct: 1530 ASHGQSGP-----RSASRQTRNEEQSGDGSR-HSGSRHHEPSTRAGSSRHSQVGQGE--- 1580
Query: 478 SDGEKAEKRSIAGIDQ 493
S G K +R + + Q
Sbjct: 1581 SAGSKTSRRQGSSVSQ 1596
Score = 37.4 bits (85), Expect = 0.063
Identities = 41/164 (25%), Positives = 62/164 (37%), Gaps = 7/164 (4%)
Query: 343 SAKGK-RNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDE 401
SA G+ R GR++ S + + QE R H R + S+ E+S
Sbjct: 3398 SAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRS 3457
Query: 402 AGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLP 461
SGS ++ + D+ G R A R S SR H SH + S
Sbjct: 3458 GHSGSHHSHTTSQGR----SDASRGQSGSRSASRQTRNDEQSGDGSR-HSWSHHHEASTQ 3512
Query: 462 AASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLEVFCEQEEKW 505
A SS S S +G+ + + S++ D + E E+W
Sbjct: 3513 ADSSRHSQSGQGQSAGPRTSRNQGSSVSQ-DSDSQGHSEDSERW 3555
Score = 37.4 bits (85), Expect = 0.063
Identities = 30/143 (20%), Positives = 56/143 (39%), Gaps = 13/143 (9%)
Query: 339 TCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESG 398
T + + + G + S+ + +EE G G + + R H + S S +SG
Sbjct: 3792 TSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGS---RHHEASTQADS--SRHSQSG 3846
Query: 399 SDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAP--------QRTKAGSKSASRTH 450
E+ S SD ++ P ++R A ++++ GS+ +H
Sbjct: 3847 QGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSH 3906
Query: 451 RGSHRKDPSLPAASSSSSSSKRG 473
R + S P S SS++ + G
Sbjct: 3907 RDTASHVQSSPVQSDSSTAKEHG 3929
Score = 34.7 bits (78), Expect = 0.41
Identities = 53/228 (23%), Positives = 83/228 (36%), Gaps = 51/228 (22%)
Query: 289 SATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTS-KGTKQEETFAKGTCRPSAKGK 347
S+ + ++ + PG S H+ + G+ T ++G S
Sbjct: 2773 SSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS---- 2828
Query: 348 RNKGGRKKRSKPSSSEEDEGPG-----------------DKQEKATQRRPHG--RERRVA 388
R + G + S+ + +EE G G + +A Q + G R RR
Sbjct: 2829 RGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 2888
Query: 389 SRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASR 448
S VS SD G D E SG AS + A ++ + GS+
Sbjct: 2889 SSVS----QDSDSEGHSEDSERWSGSAS------------RNHHGSAQEQLRDGSR---- 2928
Query: 449 THRGSHRKDPS--LPAASSSSSSSKRGKKMCSDGEKA----EKRSIAG 490
H SH++D + +A SS S R + S G+ A + RS AG
Sbjct: 2929 -HPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAG 2975
Score = 33.5 bits (75), Expect = 0.92
Identities = 33/147 (22%), Positives = 57/147 (38%), Gaps = 8/147 (5%)
Query: 343 SAKGK-RNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDE 401
SA G+ R GR++ S + + QE R H RR + S+ E+S
Sbjct: 1129 SAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRS 1188
Query: 402 AGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSK-SASRTHRGSHRKDPSL 460
SGS ++ + + R+ +++ GS+ S SR H + D S
Sbjct: 1189 GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSR 1248
Query: 461 PA------ASSSSSSSKRGKKMCSDGE 481
+ +S S +S +G + D +
Sbjct: 1249 HSQVGQEQSSGSRTSRHQGSSVSQDSD 1275
Score = 32.0 bits (71), Expect = 2.7
Identities = 52/231 (22%), Positives = 84/231 (36%), Gaps = 34/231 (14%)
Query: 298 SKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRS 357
S + T G S ++ +Q + H + + + QE R + +R+ + S
Sbjct: 743 SGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESA----RDRSGERSRRSGSFLYQVS 798
Query: 358 KPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEES--------GSDEAG-SGSDF 408
SE G ++ H + R SR S ++ GS G GS
Sbjct: 799 THKQSESSHG-WTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHH 857
Query: 409 ELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRT------------HRGSHRK 456
E S + S + A R ++GS+SASRT H GS
Sbjct: 858 EQSVDRSGHSGSHHSHTTSQGRSDA---SRGQSGSRSASRTTRNEEQSRDGSRHSGSRHH 914
Query: 457 DPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGI--DQWLEVFCEQEEKW 505
+ S A S S + +G+ S+G + +R + + D E E E+W
Sbjct: 915 EASSHADISRHSQAGQGQ---SEGSRTSRRQGSSVSQDSDSEGHSEDSERW 962
Score = 32.0 bits (71), Expect = 2.7
Identities = 40/196 (20%), Positives = 63/196 (32%), Gaps = 36/196 (18%)
Query: 309 SSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKG--------------KRNKGGRK 354
+S+ + H P +S+G +Q + R G + G +
Sbjct: 1481 ASQDGQDTIRGH--PGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPR 1538
Query: 355 KRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGE 414
S+ + +EE G G + + P R + ES + +S
Sbjct: 1539 SASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDR 1598
Query: 415 ASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGK 474
S+ EDSE S+SASR H GS R+ + + S R
Sbjct: 1599 DSEGHSEDSE----------------RRSESASRNHYGSAREQSRHGSRNPRSHQEDR-- 1640
Query: 475 KMCSDGEKAEKRSIAG 490
S G AE +G
Sbjct: 1641 --ASHGHSAESSRQSG 1654
Score = 32.0 bits (71), Expect = 2.7
Identities = 41/190 (21%), Positives = 68/190 (35%), Gaps = 20/190 (10%)
Query: 309 SSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK----------RNKGGRKKRSK 358
S+ S+ T P T + A+ + R SA + ++GGR+
Sbjct: 1770 STHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHY 1829
Query: 359 PSSSEEDEGPGD------KQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSS 412
S + G QE++ R R V+ + +++SG SGS +S
Sbjct: 1830 EQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEAS 1889
Query: 413 GEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKR 472
A S S+ G Q P R + S S +G H +D + S+S +
Sbjct: 1890 SRAD--SSRHSQVG-QGQSSGPRTSRNQGSSVSQDSDSQG-HSEDSERWSGSASRNHLGS 1945
Query: 473 GKKMCSDGEK 482
+ DG +
Sbjct: 1946 AWEQSRDGSR 1955
Score = 32.0 bits (71), Expect = 2.7
Identities = 59/235 (25%), Positives = 86/235 (36%), Gaps = 51/235 (21%)
Query: 288 KSATAKGK-----KPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRP 342
+S +A+GK + KE G SS S L + + S+ T G P
Sbjct: 2057 QSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTH-------GQSAP 2109
Query: 343 SAKGKRNK--GGRKKRSKPSSSEEDE-------GP------GDKQEKATQRRPH------ 381
S G++ + S+ S+S+E + GP G QE++ R H
Sbjct: 2110 STGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHS 2169
Query: 382 -----GRE--------RRVASRVSY-KEESGSDEAGSGSDFELSSGEASDPSDEDSEPGP 427
GR R ASR +Y KE+SG SGS +S A S S G
Sbjct: 2170 HTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD--SSRHSLVG- 2226
Query: 428 PKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEK 482
Q P R + S S G H +D + S+S + ++ DG +
Sbjct: 2227 QGQSSGPRTSRPRGSSVSQDSDSEG-HSEDSERRSGSASRNHHGSAQEQSRDGSR 2280
Score = 31.2 bits (69), Expect = 4.5
Identities = 40/183 (21%), Positives = 71/183 (38%), Gaps = 25/183 (13%)
Query: 291 TAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKR-- 348
+A+ + S R G SSQ + + P G++ +++ T S G+R
Sbjct: 1646 SAESSRQSGTRHAETSSGGQAASSQE-QARSSPGERHGSRHQQSADSST--DSGTGRRQD 1702
Query: 349 --------NKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSD 400
N+G ++ S +E Q PH + + ++R E SG
Sbjct: 1703 SSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGR- 1761
Query: 401 EAGSGSD-FELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSAS-------RTHRG 452
SGS +++S+ E S+ + + P ++++ Q + SAS R H G
Sbjct: 1762 ---SGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPG 1818
Query: 453 SHR 455
S R
Sbjct: 1819 SSR 1821
Score = 30.8 bits (68), Expect = 5.9
Identities = 40/190 (21%), Positives = 69/190 (36%), Gaps = 17/190 (8%)
Query: 295 KKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRK 354
K+PS + G+ S E K S K+E T R GK + K
Sbjct: 123 KRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSK 182
Query: 355 KRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGS-----DEAGSGSDFE 409
K + E+ GD +++ ++R + V E +G ++G + +
Sbjct: 183 KE---KNKTENTRLGDNRKRLSERLEEKEDNE--EGVYDYENTGRMTQKWIQSGHIATYY 237
Query: 410 LSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSS 469
EA D +D E +R + KS+S+ +R H +P S +
Sbjct: 238 TIQDEAYDTTDSLLEENKIYERS------RSSDGKSSSQVNRSRHENTSQVP-LQESRTR 290
Query: 470 SKRGKKMCSD 479
+RG ++ D
Sbjct: 291 KRRGSRVSQD 300
Score = 30.4 bits (67), Expect = 7.8
Identities = 48/193 (24%), Positives = 75/193 (38%), Gaps = 45/193 (23%)
Query: 329 TKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVA 388
T ++ + G PS +G++ G R ++++ SS G T R G R
Sbjct: 3068 THEQSESSHGWTGPSTRGRQ--GSRHEQAQDSSRHSASQYGQD----TIRGHPGSSR--G 3119
Query: 389 SRVSYKEESGSDEAG-SGSDFELSSGEA-SDPSDEDSEPGPPKQRKAPAPQRTKAGSKSA 446
R Y E D +G SGS ++ + SD S R ++GS+SA
Sbjct: 3120 GRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS------------------RGQSGSRSA 3161
Query: 447 SRT------------HRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGI--D 492
SRT H S + S A S S + +G+ S+G + +R + + D
Sbjct: 3162 SRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQ---SEGSRRSRRQGSSVSQD 3218
Query: 493 QWLEVFCEQEEKW 505
E E E+W
Sbjct: 3219 SDSEGHSEDSERW 3231
>gi|120587019 zinc finger protein 318 [Homo sapiens]
Length = 2279
Score = 45.1 bits (105), Expect = 3e-04
Identities = 34/111 (30%), Positives = 45/111 (40%), Gaps = 7/111 (6%)
Query: 386 RVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKS 445
R ++R S D+ G G SSG +S P+ S P PP + P R + S S
Sbjct: 3 RSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPAR-RPRSPS 61
Query: 446 ASRTHRGS------HRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAG 490
R R S R PS P A S S RG+++ G + S G
Sbjct: 62 GHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPGPAGFRGSSRG 112
Score = 30.4 bits (67), Expect = 7.8
Identities = 16/45 (35%), Positives = 24/45 (53%)
Query: 850 EEGTSSQAEAARILAASWPQNREDEEKQKLKGGPKKTKREKKAAA 894
EE + +A + + R+ E K+KL PK+ K+EKKA A
Sbjct: 1175 EERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKA 1219
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 45.1 bits (105), Expect = 3e-04
Identities = 40/187 (21%), Positives = 69/187 (36%), Gaps = 9/187 (4%)
Query: 305 DPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEE 364
+ G S+E +HT+ K+ +K + + ++ R+K + S S
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 355
Query: 365 DEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSE 424
+ ++ + ++ R H R++R +R KE+ E D E E +++ E
Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----KDRE-KEREREKEREKEKE 410
Query: 425 PGPPKQR-KAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGK---KMCSDG 480
G K R K R K K R H KD +R K K +
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 481 EKAEKRS 487
K +K+S
Sbjct: 471 RKKDKKS 477
Score = 40.8 bits (94), Expect = 0.006
Identities = 49/209 (23%), Positives = 81/209 (38%), Gaps = 9/209 (4%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
KS + + + SK R + S + K SK ++ ++ ++ R K
Sbjct: 321 KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT 380
Query: 348 RNKGGRKKRSKPSSSEEDEGPGDKQEKATQR-----RPHGRER-RVASRVSYKEESGSDE 401
R K K+R K E++ ++EK +R R RE+ R + +E E
Sbjct: 381 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 440
Query: 402 AGSGSDFELSSGEASDPS-DEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSL 460
D E + + ++D ++RK RT S +ASR R S R+
Sbjct: 441 HEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500
Query: 461 PAASSSSS--SSKRGKKMCSDGEKAEKRS 487
+ SSS S +SK K+ S R+
Sbjct: 501 RSRSSSRSPRTSKTIKRKSSRSPSPRSRN 529
Score = 36.2 bits (82), Expect = 0.14
Identities = 35/156 (22%), Positives = 66/156 (42%), Gaps = 17/156 (10%)
Query: 4 KRAAGGEPRGRELRSQ-KSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSH 62
K + + R RSQ K +++S R ++D + P KK SK + ++ R SH
Sbjct: 315 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR--SKSRERRKSRSRSH 372
Query: 63 PGGSADGPAKKKVAKVTVKSENLKVIKDEALS-------------DGDDLRDFPSDLKKA 109
+K K VK ++ + ++ D + +D D +K
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 432
Query: 110 HHLKRGATMNEDSNEEEEESENDWEEAKTRERSEKI 145
+R +D ++E+E E D E+ + ++RS++I
Sbjct: 433 REREREKEHEKD-RDKEKEKEQDKEKEREKDRSKEI 467
Score = 34.3 bits (77), Expect = 0.54
Identities = 42/220 (19%), Positives = 84/220 (38%), Gaps = 20/220 (9%)
Query: 281 SLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTK--PKTSKGTKQEETFAKG 338
+++P KS KG + S+ + SS++ S+ + +K ++ ++ + +
Sbjct: 292 AIEPESGKSNERKGGR-SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRR 350
Query: 339 TCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESG 398
+ P K +++ RK RS+ S ++ + D +EK ++ + R R KE
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRK---DTREKIKEKERVKEKDREKEREREKEREK 407
Query: 399 SDEAGSGSDFELSSGEASDPSDEDSEPGPPKQR-----------KAPAPQRTKAGSKSAS 447
E G D E ++D E ++R K + K K S
Sbjct: 408 EKERGKNKD---RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRS 464
Query: 448 RTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
+ +KD S ++S+R + + + RS
Sbjct: 465 KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 504
Score = 33.1 bits (74), Expect = 1.2
Identities = 29/141 (20%), Positives = 58/141 (41%), Gaps = 6/141 (4%)
Query: 288 KSATAKGKKPSKERL---TADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCR-PS 343
K K KK K R + + S +SS+ +S+ + +T + + R PS
Sbjct: 465 KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS 524
Query: 344 AKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAG 403
+ + K ++++ + SE E + + G+E+ + S KE+ + E
Sbjct: 525 PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 584
Query: 404 SGSDFELSSGEASDPSDEDSE 424
S E+ +A P E+++
Sbjct: 585 SSVSKEVDDKDA--PRTEENK 603
Score = 30.8 bits (68), Expect = 5.9
Identities = 36/190 (18%), Positives = 71/190 (37%), Gaps = 17/190 (8%)
Query: 295 KKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRK 354
KK SK R S + + + K K + K+++ + + +R K +
Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER----EREKEREKEKER 411
Query: 355 KRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGE 414
++K E ++ +EK +R + + KE+ E E+
Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 471
Query: 415 ASDPSDEDSEPGPP------KQRKAPAPQRTKAGSKSASRTHRGS---HRKDPSLPAASS 465
D PP ++ ++ + +R + S+S+SR+ R S RK P+ S
Sbjct: 472 KKDKKSRT----PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS 527
Query: 466 SSSSSKRGKK 475
+ K+ +K
Sbjct: 528 RNKKDKKREK 537
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 45.1 bits (105), Expect = 3e-04
Identities = 40/187 (21%), Positives = 69/187 (36%), Gaps = 9/187 (4%)
Query: 305 DPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEE 364
+ G S+E +HT+ K+ +K + + ++ R+K + S S
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 239
Query: 365 DEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSE 424
+ ++ + ++ R H R++R +R KE+ E D E E +++ E
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE----KDRE-KEREREKEREKEKE 294
Query: 425 PGPPKQR-KAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGK---KMCSDG 480
G K R K R K K R H KD +R K K +
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 481 EKAEKRS 487
K +K+S
Sbjct: 355 RKKDKKS 361
Score = 40.8 bits (94), Expect = 0.006
Identities = 49/209 (23%), Positives = 81/209 (38%), Gaps = 9/209 (4%)
Query: 288 KSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGK 347
KS + + + SK R + S + K SK ++ ++ ++ R K
Sbjct: 205 KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT 264
Query: 348 RNKGGRKKRSKPSSSEEDEGPGDKQEKATQR-----RPHGRER-RVASRVSYKEESGSDE 401
R K K+R K E++ ++EK +R R RE+ R + +E E
Sbjct: 265 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 324
Query: 402 AGSGSDFELSSGEASDPS-DEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSL 460
D E + + ++D ++RK RT S +ASR R S R+
Sbjct: 325 HEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384
Query: 461 PAASSSSS--SSKRGKKMCSDGEKAEKRS 487
+ SSS S +SK K+ S R+
Sbjct: 385 RSRSSSRSPRTSKTIKRKSSRSPSPRSRN 413
Score = 36.2 bits (82), Expect = 0.14
Identities = 35/156 (22%), Positives = 66/156 (42%), Gaps = 17/156 (10%)
Query: 4 KRAAGGEPRGRELRSQ-KSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSH 62
K + + R RSQ K +++S R ++D + P KK SK + ++ R SH
Sbjct: 199 KSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR--SKSRERRKSRSRSH 256
Query: 63 PGGSADGPAKKKVAKVTVKSENLKVIKDEALS-------------DGDDLRDFPSDLKKA 109
+K K VK ++ + ++ D + +D D +K
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 316
Query: 110 HHLKRGATMNEDSNEEEEESENDWEEAKTRERSEKI 145
+R +D ++E+E E D E+ + ++RS++I
Sbjct: 317 REREREKEHEKD-RDKEKEKEQDKEKEREKDRSKEI 351
Score = 34.3 bits (77), Expect = 0.54
Identities = 42/220 (19%), Positives = 84/220 (38%), Gaps = 20/220 (9%)
Query: 281 SLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTK--PKTSKGTKQEETFAKG 338
+++P KS KG + S+ + SS++ S+ + +K ++ ++ + +
Sbjct: 176 AIEPESGKSNERKGGR-SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRR 234
Query: 339 TCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESG 398
+ P K +++ RK RS+ S ++ + D +EK ++ + R R KE
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRK---DTREKIKEKERVKEKDREKEREREKEREK 291
Query: 399 SDEAGSGSDFELSSGEASDPSDEDSEPGPPKQR-----------KAPAPQRTKAGSKSAS 447
E G D E ++D E ++R K + K K S
Sbjct: 292 EKERGKNKD---RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRS 348
Query: 448 RTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRS 487
+ +KD S ++S+R + + + RS
Sbjct: 349 KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 388
Score = 33.1 bits (74), Expect = 1.2
Identities = 29/141 (20%), Positives = 58/141 (41%), Gaps = 6/141 (4%)
Query: 288 KSATAKGKKPSKERL---TADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCR-PS 343
K K KK K R + + S +SS+ +S+ + +T + + R PS
Sbjct: 349 KEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPS 408
Query: 344 AKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAG 403
+ + K ++++ + SE E + + G+E+ + S KE+ + E
Sbjct: 409 PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD 468
Query: 404 SGSDFELSSGEASDPSDEDSE 424
S E+ +A P E+++
Sbjct: 469 SSVSKEVDDKDA--PRTEENK 487
Score = 30.8 bits (68), Expect = 5.9
Identities = 36/190 (18%), Positives = 71/190 (37%), Gaps = 17/190 (8%)
Query: 295 KKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRK 354
KK SK R S + + + K K + K+++ + + +R K +
Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER----EREKEREKEKER 295
Query: 355 KRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGE 414
++K E ++ +EK +R + + KE+ E E+
Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 355
Query: 415 ASDPSDEDSEPGPP------KQRKAPAPQRTKAGSKSASRTHRGS---HRKDPSLPAASS 465
D PP ++ ++ + +R + S+S+SR+ R S RK P+ S
Sbjct: 356 KKDKKSRT----PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS 411
Query: 466 SSSSSKRGKK 475
+ K+ +K
Sbjct: 412 RNKKDKKREK 421
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,737,184
Number of Sequences: 37866
Number of extensions: 2004176
Number of successful extensions: 17480
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 702
Number of HSP's that attempted gapping in prelim test: 12594
Number of HSP's gapped (non-prelim): 4611
length of query: 903
length of database: 18,247,518
effective HSP length: 111
effective length of query: 792
effective length of database: 14,044,392
effective search space: 11123158464
effective search space used: 11123158464
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.