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Search of human proteins with 224593278
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
(796 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 1554 0.0
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 271 2e-72
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 253 5e-67
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 238 2e-62
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 238 2e-62
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 231 3e-60
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 221 2e-57
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 217 4e-56
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 216 7e-56
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 215 1e-55
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 211 2e-54
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 211 2e-54
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 211 3e-54
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 211 3e-54
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 210 4e-54
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 210 5e-54
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 209 6e-54
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 208 1e-53
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 208 1e-53
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 208 1e-53
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 208 2e-53
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 205 2e-52
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 204 3e-52
gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens] 200 4e-51
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 197 2e-50
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 196 5e-50
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 195 1e-49
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 195 1e-49
gi|4758112 HLA-B associated transcript 1 [Homo sapiens] 194 3e-49
gi|18375623 HLA-B associated transcript 1 [Homo sapiens] 194 3e-49
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 1554 bits (4023), Expect = 0.0
Identities = 796/796 (100%), Positives = 796/796 (100%)
Query: 1 MVLAQRRRGGCEKLRAGPQAVLASGSGFCDNMLADLGLIGTIGEDDEVPVEPESDSGDEE 60
MVLAQRRRGGCEKLRAGPQAVLASGSGFCDNMLADLGLIGTIGEDDEVPVEPESDSGDEE
Sbjct: 1 MVLAQRRRGGCEKLRAGPQAVLASGSGFCDNMLADLGLIGTIGEDDEVPVEPESDSGDEE 60
Query: 61 EEGPIVLGRRQKALGKNRSADFNPDFVFTEKEGTYDGSWALADVMSQLKKKRAATTLDEK 120
EEGPIVLGRRQKALGKNRSADFNPDFVFTEKEGTYDGSWALADVMSQLKKKRAATTLDEK
Sbjct: 61 EEGPIVLGRRQKALGKNRSADFNPDFVFTEKEGTYDGSWALADVMSQLKKKRAATTLDEK 120
Query: 121 IEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADE 180
IEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADE
Sbjct: 121 IEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADE 180
Query: 181 NILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQ 240
NILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQ
Sbjct: 181 NILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQ 240
Query: 241 PTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRE 300
PTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRE
Sbjct: 241 PTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRE 300
Query: 301 LGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSF 360
LGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSF
Sbjct: 301 LGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSF 360
Query: 361 HLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNP 420
HLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNP
Sbjct: 361 HLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNP 420
Query: 421 VRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMH 480
VRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMH
Sbjct: 421 VRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMH 480
Query: 481 ILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTM 540
ILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTM
Sbjct: 481 ILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTM 540
Query: 541 PNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFR 600
PNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFR
Sbjct: 541 PNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFR 600
Query: 601 DKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERK 660
DKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERK
Sbjct: 601 DKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERK 660
Query: 661 KEKIAKALQEFDLALRGKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAERLAKRNRR 720
KEKIAKALQEFDLALRGKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAERLAKRNRR
Sbjct: 661 KEKIAKALQEFDLALRGKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAERLAKRNRR 720
Query: 721 AKRARAMPEEEPVRGPAKKQKQGKKSVFDEELTNTSKKALKQYRAGPSFEERKQLGLPHQ 780
AKRARAMPEEEPVRGPAKKQKQGKKSVFDEELTNTSKKALKQYRAGPSFEERKQLGLPHQ
Sbjct: 721 AKRARAMPEEEPVRGPAKKQKQGKKSVFDEELTNTSKKALKQYRAGPSFEERKQLGLPHQ 780
Query: 781 RRGGNFKSKSRYKRRK 796
RRGGNFKSKSRYKRRK
Sbjct: 781 RRGGNFKSKSRYKRRK 796
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 271 bits (693), Expect = 2e-72
Identities = 154/417 (36%), Positives = 244/417 (58%), Gaps = 6/417 (1%)
Query: 215 DENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFAL 274
+E +F+D+ ++ L +A +G+ +PT IQ IP+ L G+DI A TG+GKT AFAL
Sbjct: 21 EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80
Query: 275 PVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEA 334
P+L L+ P++ LVL PTREL Q+ L + + + VGG+D SQ
Sbjct: 81 PILNALLETPQRL---FALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSL 137
Query: 335 ALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSH 394
AL P I+IATPGRLIDHL N F+L +++ L++DEADR+L+ FE ++ +I+++
Sbjct: 138 ALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPR 197
Query: 395 HRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIV 454
R+T LFSATMT +V+ L +LKNPV+ V+S L+Q +I I P++ ++ +
Sbjct: 198 DRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFI-PSK--FKDTYL 254
Query: 455 AALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQI 514
+L + M+F T R +LL +G LHG +SQ++RL +L +FK +
Sbjct: 255 VYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKAR 314
Query: 515 DILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKM 574
IL+ATDVA+RGLDI V V+NF +P K Y+HRVGRTARAGR+G++++ V + + ++
Sbjct: 315 SILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVEL 374
Query: 575 LKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQIN 631
+ I + D ++ +++ + ++ L+ E+K+ + +A N
Sbjct: 375 FQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDN 431
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 253 bits (646), Expect = 5e-67
Identities = 159/472 (33%), Positives = 256/472 (54%), Gaps = 21/472 (4%)
Query: 220 FQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLER 279
F ++ LS L++ +G KQPTP+Q CIP L G+D CA TG+GKTAAF LP+L++
Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
Query: 280 LIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAA 339
L P LVL PTREL Q+ R L + + C+ VGG+D+ +Q L
Sbjct: 64 LSEDPYGI---FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRK 120
Query: 340 PDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEY---FEEQMKEIIRMCSHHR 396
P ++IATPGRL DHL + +F + I L++DEADR+L++ F ++ I+ R
Sbjct: 121 PHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARR 180
Query: 397 QTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAA 456
QT+LFSAT+TD +++L ++ P + L Q ++ + E ++A +
Sbjct: 181 QTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVP---EKVKDAYLVH 237
Query: 457 LLTRTFTDH----VMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDE 512
L+ R +H +++FT T K + ++L LH + Q +R AL +FK
Sbjct: 238 LIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
Query: 513 QIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDER 572
IL+ATDVA+RGLDI V+ VIN P K Y+HRVGRTARAGR G++++LV + +
Sbjct: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI 357
Query: 573 KMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINT 632
++ I + K ++ + + +L+ ++ + ++ ++LEA + + +IN
Sbjct: 358 HLVHAIEEQIKKKLEEFSVEEAEVLQILTQVNVVRRE--CEIKLEAAHFD---EKKEINK 412
Query: 633 AKRLLEKGKEAVVQ---EPERSWFQTKEERKKEKIAKALQEFDLALRGKKKR 681
K+L+ +GK+ ++ + E + + K R KEK+ + L+ G K R
Sbjct: 413 RKQLILEGKDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGR 464
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 238 bits (606), Expect = 2e-62
Identities = 204/629 (32%), Positives = 304/629 (48%), Gaps = 72/629 (11%)
Query: 191 VKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIP 250
V+ + KKKKK +GGF Q M LS P+ K I G+K PTPIQ+ IP
Sbjct: 85 VRAQNKKKKK---SGGF-------------QSMGLSYPVFKGIMKKGYKVPTPIQRKTIP 128
Query: 251 VGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTR 310
V L GKD+ A A TG+GKTA F LP+ ERL Q R L+L PTREL +Q T+
Sbjct: 129 VILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGA-RALILSPTRELALQTLKFTK 187
Query: 311 QLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLIL 370
+L +F + T L +GG ++ Q AAL PDI+IATPGRL+ H+ S L S+E ++
Sbjct: 188 ELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVF 246
Query: 371 DEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTD 430
DEADR+ + F EQ++EII QT+LFSAT+ + + A L PV I ++ +T
Sbjct: 247 DEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTK 306
Query: 431 VAPFLRQEFIRIRPNREGDREAIVAALLTRTFT--DHVMLFTQTKKQAHRMHILLGLMGL 488
+ L+ F +R E + A++ LL D ++F TK A + LL +
Sbjct: 307 LNEQLKTSFFLVR---EDTKAAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRV 363
Query: 489 QVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYV 548
++ L T R L +F + L+ TD+AARGLDI + VIN++ P K ++
Sbjct: 364 SCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFL 423
Query: 549 HRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEK 608
HRVGR ARAGR+G + SLV DE L ++ R L LK + ++
Sbjct: 424 HRVGRVARAGRSGTAYSLVAPDEIPYLLDL-----HLFLGRSLTLARPLKEPSGVAGVDG 478
Query: 609 DVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKKEKIAKAL 668
+ V Q +E++ S Q L +G V ++ + +++ E I +A
Sbjct: 479 MLGRVPQSVVDEED---SGLQSTLEASLELRGLARVADNAQQQYVRSRPAPSPESIKRA- 534
Query: 669 QEFDLALRG------------KKKRKKFMKDAKKKG------EMTAEERSQ-FEILKAQM 709
+E DL G + +R + + K E+ A R ++++A+
Sbjct: 535 KEMDLVGLGLHPLFSSRFEEEELQRLRLVDSIKNYRSRATIFEINASSRDLCSQVMRAKR 594
Query: 710 FAERLA-KRNRRAKRARAMPEEEPV----RGPAKKQKQGKKSVFDEELTNTSKKALKQYR 764
+R A R ++ ++ R +E PV PA ++KQ +K +E
Sbjct: 595 QKDRKAIARFQQGQQGRQEQQEGPVGPAPSRPALQEKQPEKEEEEE-------------- 640
Query: 765 AGPSFEE--RKQLGLPHQRRGGNFKSKSR 791
AG S E+ + +G QR G N +K R
Sbjct: 641 AGESVEDIFSEVVGRKRQRSGPNRGAKRR 669
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 238 bits (606), Expect = 2e-62
Identities = 204/629 (32%), Positives = 304/629 (48%), Gaps = 72/629 (11%)
Query: 191 VKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIP 250
V+ + KKKKK +GGF Q M LS P+ K I G+K PTPIQ+ IP
Sbjct: 85 VRAQNKKKKK---SGGF-------------QSMGLSYPVFKGIMKKGYKVPTPIQRKTIP 128
Query: 251 VGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTR 310
V L GKD+ A A TG+GKTA F LP+ ERL Q R L+L PTREL +Q T+
Sbjct: 129 VILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGA-RALILSPTRELALQTLKFTK 187
Query: 311 QLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLIL 370
+L +F + T L +GG ++ Q AAL PDI+IATPGRL+ H+ S L S+E ++
Sbjct: 188 ELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRLV-HVAVEMSLKLQSVEYVVF 246
Query: 371 DEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTD 430
DEADR+ + F EQ++EII QT+LFSAT+ + + A L PV I ++ +T
Sbjct: 247 DEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTK 306
Query: 431 VAPFLRQEFIRIRPNREGDREAIVAALLTRTFT--DHVMLFTQTKKQAHRMHILLGLMGL 488
+ L+ F +R E + A++ LL D ++F TK A + LL +
Sbjct: 307 LNEQLKTSFFLVR---EDTKAAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRV 363
Query: 489 QVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYV 548
++ L T R L +F + L+ TD+AARGLDI + VIN++ P K ++
Sbjct: 364 SCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFL 423
Query: 549 HRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEK 608
HRVGR ARAGR+G + SLV DE L ++ R L LK + ++
Sbjct: 424 HRVGRVARAGRSGTAYSLVAPDEIPYLLDL-----HLFLGRSLTLARPLKEPSGVAGVDG 478
Query: 609 DVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKKEKIAKAL 668
+ V Q +E++ S Q L +G V ++ + +++ E I +A
Sbjct: 479 MLGRVPQSVVDEED---SGLQSTLEASLELRGLARVADNAQQQYVRSRPAPSPESIKRA- 534
Query: 669 QEFDLALRG------------KKKRKKFMKDAKKKG------EMTAEERSQ-FEILKAQM 709
+E DL G + +R + + K E+ A R ++++A+
Sbjct: 535 KEMDLVGLGLHPLFSSRFEEEELQRLRLVDSIKNYRSRATIFEINASSRDLCSQVMRAKR 594
Query: 710 FAERLA-KRNRRAKRARAMPEEEPV----RGPAKKQKQGKKSVFDEELTNTSKKALKQYR 764
+R A R ++ ++ R +E PV PA ++KQ +K +E
Sbjct: 595 QKDRKAIARFQQGQQGRQEQQEGPVGPAPSRPALQEKQPEKEEEEE-------------- 640
Query: 765 AGPSFEE--RKQLGLPHQRRGGNFKSKSR 791
AG S E+ + +G QR G N +K R
Sbjct: 641 AGESVEDIFSEVVGRKRQRSGPNRGAKRR 669
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 231 bits (588), Expect = 3e-60
Identities = 141/417 (33%), Positives = 221/417 (52%), Gaps = 55/417 (13%)
Query: 215 DENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFAL 274
+E +F+D+ ++ L +A +G+ +PT IQ IP+ L G+DI A TG+GKT AFAL
Sbjct: 21 EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80
Query: 275 PVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEA 334
P+L L+ P++ LVL PTREL Q+ L + + + VGG+D SQ
Sbjct: 81 PILNALLETPQRL---FALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSL 137
Query: 335 ALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSH 394
AL P I+IATPGRLIDHL N F+L +++ L++DEADR+L+ FE ++ +I+++
Sbjct: 138 ALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPR 197
Query: 395 HRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIV 454
R+T LFSATMT +V+ L +LKNPV+ V+S L+Q +I
Sbjct: 198 DRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYI-------------- 243
Query: 455 AALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQI 514
F +K ++ R L +L +FK +
Sbjct: 244 --------------FIPSKFKSKR------------------------LGSLNKFKAKAR 265
Query: 515 DILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKM 574
IL+ATDVA+RGLDI V V+NF +P K Y+HRVGRTARAGR+G++++ V + + ++
Sbjct: 266 SILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVEL 325
Query: 575 LKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQIN 631
+ I + D ++ +++ + ++ L+ E+K+ + +A N
Sbjct: 326 FQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDN 382
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 221 bits (563), Expect = 2e-57
Identities = 180/569 (31%), Positives = 282/569 (49%), Gaps = 42/569 (7%)
Query: 53 ESDSGDEEEEGPIVLGRRQKALGKNRSADFNPDFVFTEKEGTYDGSWALADVMSQLKKKR 112
E+ +GD EE +G R+ + K++ N T+ G + V +K
Sbjct: 37 ETQNGDVSEE---TMGSRK--VKKSKQKPMNVGLSETQNGGMSQEAVGNIKVTKSPQKST 91
Query: 113 AATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASE 172
T + ++ + + E+K K +K K + +EP ++ EN + SE+E++E
Sbjct: 92 VLTNGEAAMQ-------SSNSESKKKKKKKRKMVND-AEPDTKKAKTENKGK-SEEESAE 142
Query: 173 TDYSSADENILTKADTLKVKDRKKKKKKGQEAG--GFFEDASQYDENLSFQDM-NL-SRP 228
T + EN + K D D + + G G FED S F + NL +
Sbjct: 143 T--TKETENNVEKPDN----DEDESEVPSLPLGLTGAFEDTS-------FASLCNLVNEN 189
Query: 229 LLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLI---YKPR 285
LKAI MGF T IQ I L G+D+ A A TG+GKT AF +P +E ++ + PR
Sbjct: 190 TLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPR 249
Query: 286 QAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIA 345
T VL+L PTREL +Q V ++L T L +GG + ++ L +I++A
Sbjct: 250 NG--TGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVA 307
Query: 346 TPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATM 405
TPGRL+DH+ N P F +++ L++DEADR+LD FEE++K+II++ RQTMLFSAT
Sbjct: 308 TPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQ 367
Query: 406 TDEVKDLASVSL-KNPVRIFVNSNTDVAPF--LRQEFIRIRPNREGDREAIVAALLTRTF 462
T +V+DLA +SL K P+ + V+ + A L Q ++ + P+ + R ++ L +
Sbjct: 368 TRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYV-VCPSEK--RFLLLFTFLKKNR 424
Query: 463 TDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDV 522
+M+F + + LL + L V +HG Q +R +F + L+ TDV
Sbjct: 425 KKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDV 484
Query: 523 AARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAA 582
AARGLDI V ++ + P+ K Y+HRVGRTAR L+ E +K +
Sbjct: 485 AARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYLKQS 544
Query: 583 KAPVKARILPQDVILKFRDKIEKMEKDVY 611
K P+ I + ++EK+ + Y
Sbjct: 545 KVPLSEFDFSWSKISDIQSQLEKLIEKNY 573
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 217 bits (552), Expect = 4e-56
Identities = 166/549 (30%), Positives = 269/549 (48%), Gaps = 74/549 (13%)
Query: 76 KNRSADFNPDFVFTEKEGTYD-GSWALADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKE 134
++ S D+NP ++ E+ G +A + + +K+ + + +EK R + E +E
Sbjct: 280 EDTSIDYNP--LYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEE 337
Query: 135 AKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADENILTKADTLKVKDR 194
A+ KL K KEAK+ + + + ++ + DYS I TK + R
Sbjct: 338 ARLRKLRK-KEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYS-----ITTKGGKIPNPIR 391
Query: 195 KKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLL 254
S++D +L +L+ I G+K+PTPIQ+ IP+GL
Sbjct: 392 ------------------------SWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQ 427
Query: 255 GKDICACAATGTGKTAAFALPVLERLIYKPR--------QAPVTRVLVLVPTRELGIQVH 306
+DI A TG+GKTAAF +P+L + P+ Q P ++L PTREL Q+
Sbjct: 428 NRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPY--AIILAPTRELAQQIE 485
Query: 307 SVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIE 366
T + + I T +GG+ + Q LR +I+IATPGRLID L N LS
Sbjct: 486 EETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLEN-RYLVLSRCT 544
Query: 367 VLILDEADRMLDEYFEEQMKEII-------------------RMCSH-------HRQTML 400
++LDEADRM+D FE +++I+ +M ++ +RQT++
Sbjct: 545 YVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVM 604
Query: 401 FSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTR 460
F+ATM V+ LA L+ P +++ S + Q+ + E ++ + A+L +
Sbjct: 605 FTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLM---SESEKRKKLLAILEQ 661
Query: 461 TFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVAT 520
F +++F KK + L MG LHG Q QR AL K DILVAT
Sbjct: 662 GFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVAT 721
Query: 521 DVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVK 580
DVA RG+DI+ V V+N+ M I+ Y+HR+GRT RAG++G +++ + +++ + E+ +
Sbjct: 722 DVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQ 781
Query: 581 A-AKAPVKA 588
A ++PV +
Sbjct: 782 AILESPVSS 790
Score = 36.6 bits (83), Expect = 0.094
Identities = 37/157 (23%), Positives = 75/157 (47%), Gaps = 21/157 (13%)
Query: 617 EAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKKEKIAKALQEFDLALR 676
E +E ++ +AQ + + LL K K+A + + F +K ER+ E + + QE +
Sbjct: 128 EEDEHGDKKPKAQPLSLEELLAK-KKAEEEAEAKPKFLSKAEREAEALKRRQQEVE---- 182
Query: 677 GKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAERLAKRNRRAKRARAMPEEEPVRGP 736
+R++ +++ +KK R QF+ L +M E +R RR +R R E
Sbjct: 183 ---ERQRMLEEERKK-------RKQFQDLGRKML-EDPQERERRERRERMERETN----- 226
Query: 737 AKKQKQGKKSVFDEELTNTSKKALKQYRAGPSFEERK 773
+ ++G++ + +E+ + A+K+ G + R+
Sbjct: 227 GNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRR 263
Score = 33.9 bits (76), Expect = 0.61
Identities = 40/186 (21%), Positives = 78/186 (41%), Gaps = 14/186 (7%)
Query: 44 EDDEVPVEPESDSGDEEEEG-PIVLGRRQKALGKNRSADFNPDFVFTEKEGTYDGSWALA 102
+D + + E + GD++ + P+ L A+ P F+ S A
Sbjct: 120 KDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFL----------SKAER 169
Query: 103 DVMSQLKKKRAATTLDEKIEKVRKKRKT-EDKEAKSGKLEKEKEAKEGSEPKEQEDLQEN 161
+ + ++++ +E+ RKKRK +D K + +E+E +E E E+E
Sbjct: 170 EAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNE 229
Query: 162 DEEGSEDEASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQ 221
DEEG + E D S + + + + +K R++ + F DAS+ D ++ +
Sbjct: 230 DEEGRQKIREEKD-KSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASE-DTSIDYN 287
Query: 222 DMNLSR 227
+ R
Sbjct: 288 PLYKER 293
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 216 bits (550), Expect = 7e-56
Identities = 137/383 (35%), Positives = 203/383 (53%), Gaps = 28/383 (7%)
Query: 219 SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLE 278
SF D+ + ++ I + +PTP+QK IP+ +D+ ACA TG+GKTAAF LP+L
Sbjct: 181 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 240
Query: 279 RLIY-----------------KPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTC 321
++ + +Q P++ LVL PTREL +Q++ R+ + + C
Sbjct: 241 QIYSDGPGEALRAMKENGRYGRRKQYPIS--LVLAPTRELAVQIYEEARKFSYRSRVRPC 298
Query: 322 LAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYF 381
+ GG D+ Q L +L+ATPGRL+D + L + L+LDEADRMLD F
Sbjct: 299 VVYGGADIGQQIRDLERGCHLLVATPGRLVDMMER-GKIGLDFCKYLVLDEADRMLDMGF 357
Query: 382 EEQMKEIIRMCSHH----RQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQ 437
E Q++ I+ + R TM+FSAT E++ LA L + + V + + Q
Sbjct: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417
Query: 438 EFIRIRPNREGDREAIVAALLTRTFTDHVML-FTQTKKQAHRMHILLGLMGLQVGELHGN 496
+ + + E D+ + + LL T D + L F +TKK A + L G +HG+
Sbjct: 418 KVVWVE---ESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 474
Query: 497 LSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTAR 556
SQ R EAL +F+ + ILVAT VAARGLDI VK VINF +P+ I+ YVHR+GRT R
Sbjct: 475 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGR 534
Query: 557 AGRAGRSVSLVGEDERKMLKEIV 579
G G + S E + K+++
Sbjct: 535 VGNLGLATSFFNERNINITKDLL 557
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 215 bits (547), Expect = 1e-55
Identities = 133/395 (33%), Positives = 211/395 (53%), Gaps = 6/395 (1%)
Query: 215 DENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFAL 274
+E F D LS+ LK + ++ T IQK I + L GKD+ A TG+GKT AF +
Sbjct: 66 NEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLV 125
Query: 275 PVLERLIYKPRQAPVTR--VLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQ 332
PVLE L Y+ + VL++ PTREL Q V R++ + + + L +GG D+K +
Sbjct: 126 PVLEAL-YRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHE 184
Query: 333 EAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMC 392
+ +IL+ TPGRL+ H+ SFH + +++L+LDEADR+LD F + M +I
Sbjct: 185 AERINNI-NILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENL 243
Query: 393 SHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREA 452
RQT+LFSAT T VKDLA +SLKNP ++V+ + E I +
Sbjct: 244 PKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISV 303
Query: 453 IVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLM-GLQVGELHGNLSQTQRLEALRRFKD 511
+ + L + ++ F+ K+ + + L G+ + LHG Q +R+E F
Sbjct: 304 LYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVR 363
Query: 512 EQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDE 571
++ +L ATD+AARGLD V V+ F P Y+HR GRTAR G ++ ++ E
Sbjct: 364 KRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSE 423
Query: 572 RKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKM 606
+ M++++++ K PVK + + ++ + K+E +
Sbjct: 424 KAMVQQLLQ-KKVPVKEIKINPEKLIDVQKKLESI 457
Score = 31.2 bits (69), Expect = 4.0
Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 13/122 (10%)
Query: 108 LKKKRAATTLDEKIEKV--RKKRKTEDKEAKSGKLEKEKEA-KEGSEPKEQED--LQEND 162
L K + ++K +K RKK K + +E + + E +EA K ++ K++E+ L +D
Sbjct: 722 LHKAKERLQEEDKFDKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSD 781
Query: 163 EEGSEDEASETD-------YSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYD 215
++ +D+ + Y S++++ + K+ D KKK+ + + ED
Sbjct: 782 DDDDDDDGFDPSTLPDPDKYRSSEDSDSEDMEN-KISDTKKKQGMKKRSNSEVEDVGPTS 840
Query: 216 EN 217
N
Sbjct: 841 HN 842
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 211 bits (538), Expect = 2e-54
Identities = 133/383 (34%), Positives = 205/383 (53%), Gaps = 28/383 (7%)
Query: 219 SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLE 278
+F D+++ ++ I + +PTP+QK IP+ +D+ ACA TG+GKTAAF LP+L
Sbjct: 179 NFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILS 238
Query: 279 RLIY-----------------KPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTC 321
++ + +Q P++ LVL PTREL +Q++ R+ + + C
Sbjct: 239 QIYTDGPGEALKAVKENGRYGRRKQYPIS--LVLAPTRELAVQIYEEARKFSYRSRVRPC 296
Query: 322 LAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYF 381
+ GG D+ Q L +L+ATPGRL+D + L + L+LDEADRMLD F
Sbjct: 297 VVYGGADIGQQIRDLERGCHLLVATPGRLVDMMER-GKIGLDFCKYLVLDEADRMLDMGF 355
Query: 382 EEQMKEIIRMCSHH----RQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQ 437
E Q++ I+ + R TM+FSAT E++ LA L + + V + + Q
Sbjct: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415
Query: 438 EFIRIRPNREGDREAIVAALLTRTFTDHVML-FTQTKKQAHRMHILLGLMGLQVGELHGN 496
+ + + + D+ + + +L T +D + L F +TKK A + L G +HG+
Sbjct: 416 KVVWVE---DLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 472
Query: 497 LSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTAR 556
SQ R EAL +F+ + ILVAT VAARGLDI V+ VINF +P+ I+ YVHR+GRT R
Sbjct: 473 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532
Query: 557 AGRAGRSVSLVGEDERKMLKEIV 579
G G + S E + K+++
Sbjct: 533 VGNLGLATSFFNEKNMNITKDLL 555
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 211 bits (538), Expect = 2e-54
Identities = 133/383 (34%), Positives = 205/383 (53%), Gaps = 28/383 (7%)
Query: 219 SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLE 278
+F D+++ ++ I + +PTP+QK IP+ +D+ ACA TG+GKTAAF LP+L
Sbjct: 179 NFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILS 238
Query: 279 RLIY-----------------KPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTC 321
++ + +Q P++ LVL PTREL +Q++ R+ + + C
Sbjct: 239 QIYTDGPGEALKAVKENGRYGRRKQYPIS--LVLAPTRELAVQIYEEARKFSYRSRVRPC 296
Query: 322 LAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYF 381
+ GG D+ Q L +L+ATPGRL+D + L + L+LDEADRMLD F
Sbjct: 297 VVYGGADIGQQIRDLERGCHLLVATPGRLVDMMER-GKIGLDFCKYLVLDEADRMLDMGF 355
Query: 382 EEQMKEIIRMCSHH----RQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQ 437
E Q++ I+ + R TM+FSAT E++ LA L + + V + + Q
Sbjct: 356 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 415
Query: 438 EFIRIRPNREGDREAIVAALLTRTFTDHVML-FTQTKKQAHRMHILLGLMGLQVGELHGN 496
+ + + + D+ + + +L T +D + L F +TKK A + L G +HG+
Sbjct: 416 KVVWVE---DLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGD 472
Query: 497 LSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTAR 556
SQ R EAL +F+ + ILVAT VAARGLDI V+ VINF +P+ I+ YVHR+GRT R
Sbjct: 473 RSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGR 532
Query: 557 AGRAGRSVSLVGEDERKMLKEIV 579
G G + S E + K+++
Sbjct: 533 VGNLGLATSFFNEKNMNITKDLL 555
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 211 bits (536), Expect = 3e-54
Identities = 150/501 (29%), Positives = 248/501 (49%), Gaps = 45/501 (8%)
Query: 117 LDEKIEKVRKKRKTEDKEAKSGK-----LEKEKEAKE-----------GSEPKEQEDLQE 160
++++ + K+ + +DKE K+ K +E+E + + G +E+ED E
Sbjct: 123 VEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLE 182
Query: 161 NDEEGSED-------------EASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGF 207
D +G+ + SE DY ++N + + + ++ +
Sbjct: 183 YDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLR 242
Query: 208 FEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTG 267
A+ SF L+ I + QPTPIQ +PV L G+D+ A TG+G
Sbjct: 243 VSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSG 302
Query: 268 KTAAFALPVLERLI----YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLA 323
KTAAF P+L ++ +P P+ +++ PTREL Q+H+ ++ + N+ +
Sbjct: 303 KTAAFIWPMLIHIMDQKELEPGDGPIA--VIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
Query: 324 VGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEE 383
GG + Q AL+ +I++ TPGRLIDH+ + +L + L+ DEADRM D FE
Sbjct: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEY 419
Query: 384 QMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVN----SNTDVAPFLRQEF 439
Q++ I RQT+LFSAT +++ LA L +P+R+ +N DV + E
Sbjct: 420 QVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIV--EI 477
Query: 440 IRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQ 499
+ P++ + L+ T + V+LF K A + L G +G LHG++ Q
Sbjct: 478 LHSGPSKWN---WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQ 534
Query: 500 TQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGR 559
++R + + FK + I +LVATDVAARGLDI +KTVIN+ + I + HR+GRT RAG
Sbjct: 535 SERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGE 594
Query: 560 AGRSVSLVGEDERKMLKEIVK 580
G + +L+ + ++V+
Sbjct: 595 KGVAYTLLTPKDSNFAGDLVR 615
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 211 bits (536), Expect = 3e-54
Identities = 150/501 (29%), Positives = 248/501 (49%), Gaps = 45/501 (8%)
Query: 117 LDEKIEKVRKKRKTEDKEAKSGK-----LEKEKEAKE-----------GSEPKEQEDLQE 160
++++ + K+ + +DKE K+ K +E+E + + G +E+ED E
Sbjct: 123 VEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLE 182
Query: 161 NDEEGSED-------------EASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGF 207
D +G+ + SE DY ++N + + + ++ +
Sbjct: 183 YDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLR 242
Query: 208 FEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTG 267
A+ SF L+ I + QPTPIQ +PV L G+D+ A TG+G
Sbjct: 243 VSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSG 302
Query: 268 KTAAFALPVLERLI----YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLA 323
KTAAF P+L ++ +P P+ +++ PTREL Q+H+ ++ + N+ +
Sbjct: 303 KTAAFIWPMLIHIMDQKELEPGDGPIA--VIVCPTRELCQQIHAECKRFGKAYNLRSVAV 360
Query: 324 VGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEE 383
GG + Q AL+ +I++ TPGRLIDH+ + +L + L+ DEADRM D FE
Sbjct: 361 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVSYLVFDEADRMFDMGFEY 419
Query: 384 QMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVN----SNTDVAPFLRQEF 439
Q++ I RQT+LFSAT +++ LA L +P+R+ +N DV + E
Sbjct: 420 QVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIV--EI 477
Query: 440 IRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQ 499
+ P++ + L+ T + V+LF K A + L G +G LHG++ Q
Sbjct: 478 LHSGPSKWN---WLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQ 534
Query: 500 TQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGR 559
++R + + FK + I +LVATDVAARGLDI +KTVIN+ + I + HR+GRT RAG
Sbjct: 535 SERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGE 594
Query: 560 AGRSVSLVGEDERKMLKEIVK 580
G + +L+ + ++V+
Sbjct: 595 KGVAYTLLTPKDSNFAGDLVR 615
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 210 bits (535), Expect = 4e-54
Identities = 126/383 (32%), Positives = 214/383 (55%), Gaps = 16/383 (4%)
Query: 201 GQEAGGFFEDASQYDENL-SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDIC 259
G E G E S ++E + SF DMNLS LL+ I A GF++P+ IQ+ I + G D+
Sbjct: 16 GMEPEGVIE--SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVI 73
Query: 260 ACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNIT 319
A A +GTGKTA FA+ +L+++ T+ LVL PTREL Q+ V L + +
Sbjct: 74 AQAQSGTGKTATFAISILQQI---ELDLKATQALVLAPTRELAQQIQKVVMALGDYMGAS 130
Query: 320 TCLAVGGLDVKSQEAALRA-APDILIATPGRLIDHLHN---CPSFHLSSIEVLILDEADR 375
+GG +V+++ L+ AP I++ TPGR+ D L+ P + I++ +LDEAD
Sbjct: 131 CHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKY----IKMFVLDEADE 186
Query: 376 MLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFL 435
ML F++Q+ +I + + + Q +L SATM +V ++ +++P+RI V +
Sbjct: 187 MLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGI 246
Query: 436 RQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHG 495
RQ +I + E + + T T T V +F T+++ + + V +HG
Sbjct: 247 RQFYINVE-REEWKLDTLCDLYETLTITQAV-IFINTRRKVDWLTEKMHARDFTVSAMHG 304
Query: 496 NLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTA 555
++ Q +R +R F+ +L+ TD+ ARG+D++ V VIN+ +P ++Y+HR+GR
Sbjct: 305 DMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGG 364
Query: 556 RAGRAGRSVSLVGEDERKMLKEI 578
R GR G ++++V E++++ L++I
Sbjct: 365 RFGRKGVAINMVTEEDKRTLRDI 387
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 210 bits (534), Expect = 5e-54
Identities = 165/592 (27%), Positives = 279/592 (47%), Gaps = 69/592 (11%)
Query: 110 KKRAATTLDEKIEKVRKKRKTEDKEAKSGKL-EKEKEAKEGSEPKEQEDLQENDEEGSED 168
+K++ T+ + + V K+ D + K G+L E +++A E S +E+ DLQ
Sbjct: 254 EKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQ--------- 304
Query: 169 EASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENL---------- 218
+ T Y + +L D K++ +K E + SQ + N+
Sbjct: 305 -TALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAK-MSQEEVNVFRLEMEGITV 362
Query: 219 ----------SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGK 268
S+ +S +L ++ G+++PTPIQ IP + G+D+ A TG+GK
Sbjct: 363 KGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGK 422
Query: 269 TAAFALPVLERLI----YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAV 324
T AF LP+ ++ + + P+ +++ PTREL +Q+ ++ ++ +
Sbjct: 423 TIAFLLPMFRHIMDQRSLEEGEGPIA--VIMTPTRELALQITKECKKFSKTLGLRVVCVY 480
Query: 325 GGLDVKSQEAALRAAPDILIATPGRLIDHL--HNCPSFHLSSIEVLILDEADRMLDEYFE 382
GG + Q A L+ +I++ TPGR+ID L ++ +L + ++LDEADRM D FE
Sbjct: 481 GGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFE 540
Query: 383 EQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRI 442
Q+ I+ RQT++FSAT ++ LA L P+ + V + V + Q+ I I
Sbjct: 541 PQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVI 600
Query: 443 RPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVG--ELHGNLSQT 500
E +++ + L + + + KQ H +L LM LHG + Q
Sbjct: 601 ----EEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQY 656
Query: 501 QRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRA 560
R + FK+ +LVAT VAARGLD++ + V+N++ PN + YVHR GRT RAG
Sbjct: 657 DRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNK 716
Query: 561 GRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEE 620
G + + + ED+ + +I+KA + + +P D +EK+ D
Sbjct: 717 GYAYTFITEDQARYAGDIIKALE--LSGTAVPPD--------LEKLWSDF---------- 756
Query: 621 KEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKKEKIAKALQEFD 672
K+ Q++E +I K GK E E++ E +K +K A LQ+ D
Sbjct: 757 KDQQKAEGKI-IKKSSGFSGKGFKFDETEQA--LANERKKLQKAALGLQDSD 805
Score = 31.6 bits (70), Expect = 3.0
Identities = 21/102 (20%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 109 KKKRAATTLDEKIEKVRKKRKTE------DKEAKSGKLEKEKEAKEGSE-PKEQEDLQEN 161
+++R + + D + + R + + +K K+ + KE +G E KE++ +++
Sbjct: 80 RERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDD 139
Query: 162 DEEGSEDEASETDYSSADENILTKADTLKVKDRKKKKKKGQE 203
E+ E +A D + +E + + + ++ K R++++KK E
Sbjct: 140 KEDEKEKDAGNFDQNKLEEEMRKRKERVE-KWREEQRKKAME 180
Score = 31.6 bits (70), Expect = 3.0
Identities = 29/113 (25%), Positives = 58/113 (51%), Gaps = 15/113 (13%)
Query: 70 RQKALGKNRSADFNPDFVFTEKEGTYD-GSWALADVMSQLKKKRAATTLDEKIEKVRKKR 128
++K G S + D E E D G++ + +++K++ E++EK R+++
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRK------ERVEKWREEQ 174
Query: 129 KTEDKEAKSGKLEKE-KEAKEG------SEPKEQEDLQENDEEGSEDEASETD 174
+ + E G+L+KE +E K+G + +++D E ++EG+E E E D
Sbjct: 175 RKKAME-NIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELD 226
Score = 30.4 bits (67), Expect = 6.7
Identities = 46/218 (21%), Positives = 88/218 (40%), Gaps = 31/218 (14%)
Query: 545 KHYVHRVGRTARAGRAGRSVSLV------GEDERKMLKEIVKAAKAPVKARILPQDVILK 598
+HY R R+G RS S G+D R ++ + + +
Sbjct: 6 RHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERS------------R 53
Query: 599 FRDKIEKMEKDVYAVLQLEAEEK----EMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQ 654
RDK +D + + + E+ E ++S ++ R +G+ + P +
Sbjct: 54 SRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKK 113
Query: 655 TKEE-RKKEKIAKALQEFDLALRGKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAER 713
T+ R KEK + + + KKK K +D K+K ++ E ++ + ER
Sbjct: 114 TENRSRSKEKT-----DGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRK--ER 166
Query: 714 LAKRNRRAKRARAMPEEEPVRGPAKKQKQGKKSVFDEE 751
+ K R +R +AM ++ ++ KQGKK +++
Sbjct: 167 VEKW-REEQRKKAMENIGELKKEIEEMKQGKKWSLEDD 203
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 209 bits (533), Expect = 6e-54
Identities = 129/390 (33%), Positives = 221/390 (56%), Gaps = 14/390 (3%)
Query: 193 DRKKKKKKGQEAGGFFEDASQYDENL-SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPV 251
+R+ +G + G E S ++E + +F DMNL LL+ I A GF++P+ IQ+ I
Sbjct: 9 NREHGGPEGMDPDGVIE--SNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIP 66
Query: 252 GLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQ 311
+ G D+ A A +GTGKTA FA+ +L++L + ++ T+ LVL PTREL Q+ V
Sbjct: 67 CIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKE---TQALVLAPTRELAQQIQKVILA 123
Query: 312 LAQFCNITTCLAVGGLDVKSQEAALRA-APDILIATPGRLIDHLHNCPSFHLSS--IEVL 368
L + T +GG +V+++ L+A AP I++ TPGR+ D L+ +LS I++
Sbjct: 124 LGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRR---YLSPKWIKMF 180
Query: 369 ILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSN 428
+LDEAD ML F++Q+ EI + + Q +L SATM +V ++ +++P+RI V
Sbjct: 181 VLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE 240
Query: 429 TDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGL 488
++Q +I + E + + T T T V +F T+++ + +
Sbjct: 241 ELTLEGIKQFYINVE-REEWKLDTLCDLYETLTITQAV-IFLNTRRKVDWLTEKMHARDF 298
Query: 489 QVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYV 548
V LHG++ Q +R +R F+ +L+ TD+ ARG+D++ V VIN+ +P ++Y+
Sbjct: 299 TVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYI 358
Query: 549 HRVGRTARAGRAGRSVSLVGEDERKMLKEI 578
HR+GR R GR G +++ V E+++++L++I
Sbjct: 359 HRIGRGGRFGRKGVAINFVTEEDKRILRDI 388
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 208 bits (530), Expect = 1e-53
Identities = 136/377 (36%), Positives = 209/377 (55%), Gaps = 20/377 (5%)
Query: 218 LSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVL 277
L+F++ NL + L I G+ + TP+QK IP+ L G+D+ ACA TG+GKTAAF LP+L
Sbjct: 288 LTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 347
Query: 278 ERLI--------YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDV 329
++ +K Q P +++ PTREL Q++ R+ + + + GG +
Sbjct: 348 AHMMHDGITASRFKELQEP--ECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQL 405
Query: 330 KSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEII 389
+ +IL ATPGRL+D + L I+ L+LDEADRMLD F +MK++I
Sbjct: 406 GHSIRQIVQGCNILCATPGRLMDIIGK-EKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464
Query: 390 RM----CSHHRQTMLFSATMTDEVKDLASVSLK-NPVRIFVNSNTDVAPFLRQEFIRIRP 444
RQT++FSAT +E++ LA+ LK N + + V ++Q +++
Sbjct: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQV-- 522
Query: 445 NREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLE 504
+ RE +V +L + M+F +TKK+A + L + +HG+ Q +R +
Sbjct: 523 GQFSKREKLVE-ILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQ 581
Query: 505 ALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSV 564
AL F+ + +LVAT VAARGLDIE V+ VINF +P+TI YVHR+GRT R G GR++
Sbjct: 582 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 641
Query: 565 SLVG-EDERKMLKEIVK 580
S E + + + +VK
Sbjct: 642 SFFDLESDNHLAQPLVK 658
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 208 bits (530), Expect = 1e-53
Identities = 136/377 (36%), Positives = 209/377 (55%), Gaps = 20/377 (5%)
Query: 218 LSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVL 277
L+F++ NL + L I G+ + TP+QK IP+ L G+D+ ACA TG+GKTAAF LP+L
Sbjct: 288 LTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 347
Query: 278 ERLI--------YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDV 329
++ +K Q P +++ PTREL Q++ R+ + + + GG +
Sbjct: 348 AHMMHDGITASRFKELQEP--ECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQL 405
Query: 330 KSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEII 389
+ +IL ATPGRL+D + L I+ L+LDEADRMLD F +MK++I
Sbjct: 406 GHSIRQIVQGCNILCATPGRLMDIIGK-EKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464
Query: 390 RM----CSHHRQTMLFSATMTDEVKDLASVSLK-NPVRIFVNSNTDVAPFLRQEFIRIRP 444
RQT++FSAT +E++ LA+ LK N + + V ++Q +++
Sbjct: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQV-- 522
Query: 445 NREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLE 504
+ RE +V +L + M+F +TKK+A + L + +HG+ Q +R +
Sbjct: 523 GQFSKREKLVE-ILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQ 581
Query: 505 ALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSV 564
AL F+ + +LVAT VAARGLDIE V+ VINF +P+TI YVHR+GRT R G GR++
Sbjct: 582 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 641
Query: 565 SLVG-EDERKMLKEIVK 580
S E + + + +VK
Sbjct: 642 SFFDLESDNHLAQPLVK 658
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 208 bits (530), Expect = 1e-53
Identities = 136/377 (36%), Positives = 209/377 (55%), Gaps = 20/377 (5%)
Query: 218 LSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVL 277
L+F++ NL + L I G+ + TP+QK IP+ L G+D+ ACA TG+GKTAAF LP+L
Sbjct: 254 LTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 313
Query: 278 ERLI--------YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDV 329
++ +K Q P +++ PTREL Q++ R+ + + + GG +
Sbjct: 314 AHMMHDGITASRFKELQEP--ECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQL 371
Query: 330 KSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEII 389
+ +IL ATPGRL+D + L I+ L+LDEADRMLD F +MK++I
Sbjct: 372 GHSIRQIVQGCNILCATPGRLMDIIGK-EKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 430
Query: 390 RM----CSHHRQTMLFSATMTDEVKDLASVSLK-NPVRIFVNSNTDVAPFLRQEFIRIRP 444
RQT++FSAT +E++ LA+ LK N + + V ++Q +++
Sbjct: 431 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQV-- 488
Query: 445 NREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLE 504
+ RE +V +L + M+F +TKK+A + L + +HG+ Q +R +
Sbjct: 489 GQFSKREKLVE-ILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQ 547
Query: 505 ALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSV 564
AL F+ + +LVAT VAARGLDIE V+ VINF +P+TI YVHR+GRT R G GR++
Sbjct: 548 ALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAI 607
Query: 565 SLVG-EDERKMLKEIVK 580
S E + + + +VK
Sbjct: 608 SFFDLESDNHLAQPLVK 624
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 208 bits (529), Expect = 2e-53
Identities = 166/580 (28%), Positives = 279/580 (48%), Gaps = 45/580 (7%)
Query: 46 DEVPV---EPESDSGDEEEEGPIVLGRR------QKALGKNRSADFNPDFVFTEKEGTYD 96
DEVP E++ D+E+ P V R+ QK L + R E+E
Sbjct: 14 DEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGA-------AEEEQQDS 66
Query: 97 GSWALADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEG-SEPKEQ 155
GS D ++ +L ++ + +++K + + AK +L++E++ E +E +
Sbjct: 67 GSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRAL 126
Query: 156 EDLQENDEEGSEDEASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYD 215
++E + + D+ +T ++ +L+ ++ + RKK E G
Sbjct: 127 MSVKEMAKGITYDDPIKTSWTPP-RYVLSMSEERHERVRKKYHIL-VEGDGIPPPIK--- 181
Query: 216 ENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALP 275
SF++M +L+ + G PTPIQ IP L G+D+ A TG+GKT F LP
Sbjct: 182 ---SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLP 238
Query: 276 VL-------ERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCN------ITTCL 322
V+ +RL + R+ P L++ P+REL Q H + + + L
Sbjct: 239 VIMFCLEQEKRLPFSKREGPYG--LIICPSRELARQTHGILEYYCRLLQEDSSPLLRCAL 296
Query: 323 AVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFE 382
+GG+ VK Q +R +++ATPGRL+D L L L LDEADRM+D FE
Sbjct: 297 CIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQK-KMVSLDICRYLALDEADRMIDMGFE 355
Query: 383 EQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRI 442
++ I RQT+LFSATM ++++ A +L PV I V + + QE +
Sbjct: 356 GDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYV 415
Query: 443 RPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQR 502
+ E + + L +T V++F + K +H L L G++ +HG Q +R
Sbjct: 416 K---EEAKMVYLLECLQKT-PPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEER 471
Query: 503 LEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGR 562
+A+ F++ + D+LVATDVA++GLD ++ VIN+ MP I++YVHR+GRT R+G G
Sbjct: 472 TKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGI 531
Query: 563 SVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDK 602
+ + + + + + +KA K ++ P +L D+
Sbjct: 532 ATTFINKACDESVLMDLKALLLEAKQKVPPVLQVLHCGDE 571
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 205 bits (521), Expect = 2e-52
Identities = 120/385 (31%), Positives = 209/385 (54%), Gaps = 6/385 (1%)
Query: 194 RKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGL 253
RK+ K+ FE + + D +F M L LL+ I A GF++P+ IQ+ I +
Sbjct: 14 RKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73
Query: 254 LGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLA 313
G+D+ A + +GTGKTA F++ VL+ L + R+ T+ L+L PTREL +Q+ L
Sbjct: 74 KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRE---TQALILAPTRELAVQIQKGLLALG 130
Query: 314 QFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEA 373
+ N+ +GG +V L ++ TPGR+ D + S +I++L+LDEA
Sbjct: 131 DYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEA 189
Query: 374 DRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAP 433
D ML++ F+EQ+ ++ R Q +L SAT+ E+ ++ + + +P+RI V +
Sbjct: 190 DEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLE 249
Query: 434 FLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGEL 493
++Q F+ + E + + T T T V +F TK++ + + V +
Sbjct: 250 GIKQFFVAVE-REEWKFDTLCDLYDTLTITQAV-IFCNTKRKVDWLTEKMREANFTVSSM 307
Query: 494 HGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGR 553
HG++ Q +R ++ F+ +L++TDV ARGLD+ V +IN+ +PN + Y+HR+GR
Sbjct: 308 HGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGR 367
Query: 554 TARAGRAGRSVSLVGEDERKMLKEI 578
+ R GR G +++ V D+ ++L++I
Sbjct: 368 SGRYGRKGVAINFVKNDDIRILRDI 392
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 204 bits (518), Expect = 3e-52
Identities = 137/455 (30%), Positives = 231/455 (50%), Gaps = 15/455 (3%)
Query: 142 KEKEAKEGSEPKEQEDLQENDEEGSEDEAS-ETDYSSADENILTKADTLKVKDRKKKKKK 200
K K + E +E+ L + SE E+ Y + + ++++ K
Sbjct: 132 KAKHLLQVKEKEEKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLK----- 186
Query: 201 GQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICA 260
Q+ G + + F+ +L L + G++ PTPIQ IPVGLLG+DI A
Sbjct: 187 -QQLGILVQGQEVTRPIIDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILA 245
Query: 261 CAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQ-FCNIT 319
A TG+GKTAAF LPV+ R +++ + L+L PTREL IQ+ ++L +
Sbjct: 246 SADTGSGKTAAFLLPVIMRALFESK---TPSALILTPTRELAIQIERQAKELMSGLPRMK 302
Query: 320 TCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDE 379
T L VGGL + Q L+ ++IATPGRL+D + S L ++++++DEAD ML
Sbjct: 303 TVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKM 361
Query: 380 YFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEF 439
F++Q+ +I+ + QT+L SAT+ ++ LAS L NPVRI +RQ
Sbjct: 362 GFQQQVLDILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQII 421
Query: 440 IRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRM-HILLGLMGLQVGELHGNLS 498
+ + + ++ + F V++F K A + + + GL+ +H S
Sbjct: 422 LWVEDPAK-KKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKS 480
Query: 499 QTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAG 558
Q +R L+ + +++V+T V RGLD+ V+ V+NF MP+++ YVH++GR R G
Sbjct: 481 QIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLG 540
Query: 559 RAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQ 593
+ G +++ + + +++ +I K K P + + PQ
Sbjct: 541 QNGTAITFINNNSKRLFWDIAKRVK-PTGSILPPQ 574
>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
Length = 547
Score = 200 bits (509), Expect = 4e-51
Identities = 142/472 (30%), Positives = 226/472 (47%), Gaps = 44/472 (9%)
Query: 216 ENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALP 275
E L F+ M L LL+A+T +G+ +PT IQ+ IP+ L GKD+ A A TG+GKTAA+A+P
Sbjct: 5 EALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIP 64
Query: 276 VLERLIYKPRQAPVT----RVLVLVPTRELGIQVHSVTRQLAQFC--NITTCLAVGGLDV 329
+L+ L+++ PV R LVLVPT+EL Q S+ +QLA +C ++ D
Sbjct: 65 MLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDS 124
Query: 330 KSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEII 389
SQ A L PD+++ TP R++ HL S+E+L++DEAD + FEE++K ++
Sbjct: 125 VSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLL 184
Query: 390 RMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGD 449
Q L SAT ++V+ L + L NPV + + + P Q+F + E
Sbjct: 185 CHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDK 244
Query: 450 REAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRF 509
+ A L +LF T ++++R+ + L + L+G L R + +F
Sbjct: 245 FLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQF 304
Query: 510 KDEQIDILVATDV---------------------------AARGLDIEGVKTVINFTMPN 542
D ++ATD ARG+D V V+NF +P
Sbjct: 305 NQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPP 364
Query: 543 TIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDK 602
T + Y+HR GRTARA G ++ V E+ L +I + + IL L ++ +
Sbjct: 365 TPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPIL-----LPYQFR 419
Query: 603 IEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQ 654
+E++E Y M+ Q RL E +E + E +++F+
Sbjct: 420 MEEIEGFRYRC------RDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFE 465
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 197 bits (502), Expect = 2e-50
Identities = 125/371 (33%), Positives = 195/371 (52%), Gaps = 8/371 (2%)
Query: 218 LSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVL 277
L+F + N ++ I F +PT IQ PV L G D+ A TG+GKT ++ LP +
Sbjct: 94 LNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAI 153
Query: 278 ERLIYKP----RQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQE 333
+ ++P P+ LVL PTREL QV V + + C + + GG Q
Sbjct: 154 VHINHQPFLERGDGPIC--LVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQI 211
Query: 334 AALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCS 393
L +I IATPGRLID L C +L L+LDEADRMLD FE Q+++I+
Sbjct: 212 RDLERGVEICIATPGRLIDFLE-CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIR 270
Query: 394 HHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAI 453
RQT+++SAT EV+ LA LK+ + I + + A + + + + E D + I
Sbjct: 271 PDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLI 330
Query: 454 -VAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDE 512
+ + + ++F +TK++ + + G +HG+ SQ +R L FK
Sbjct: 331 RLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHG 390
Query: 513 QIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDER 572
+ IL+ATDVA+RGLD+E VK VIN+ PN+ + Y+HR+GRTAR+ + G + + +
Sbjct: 391 KAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNI 450
Query: 573 KMLKEIVKAAK 583
K + +++ +
Sbjct: 451 KQVSDLISVLR 461
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 196 bits (499), Expect = 5e-50
Identities = 129/354 (36%), Positives = 192/354 (54%), Gaps = 6/354 (1%)
Query: 229 LLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPR--- 285
+++ I GF++PTPIQ P+ L G D+ A TGTGKT + +P L+ +P
Sbjct: 253 VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKG 312
Query: 286 QAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIA 345
Q +LVL PTREL +QV + + + + + GG + Q L+ DI+IA
Sbjct: 313 QRNRPGMLVLTPTRELALQVEGECCKYS-YKGLRSVCVYGGGNRDEQIEELKKGVDIIIA 371
Query: 346 TPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATM 405
TPGRL D L +L +I L+LDEAD+MLD FE Q+ +I+ RQT++ SAT
Sbjct: 372 TPGRLND-LQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATW 430
Query: 406 TDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDH 465
V LA LK P+ ++V + VA ++ I + E + L + + TD
Sbjct: 431 PHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEE-KWSHMQTFLQSMSSTDK 489
Query: 466 VMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAAR 525
V++F K A + L L + V LHG+ Q R +AL FK ++ IL+ATD+A+R
Sbjct: 490 VIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASR 549
Query: 526 GLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIV 579
GLD+ V V NF P I+ YVHR+GRT RAGR G S++ + ++ ++ E++
Sbjct: 550 GLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELI 603
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 195 bits (496), Expect = 1e-49
Identities = 130/374 (34%), Positives = 198/374 (52%), Gaps = 12/374 (3%)
Query: 229 LLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKP---R 285
LLK+I +G +PTPIQ P+ L G D+ A TGTGKT ++ +P L +P
Sbjct: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISRE 292
Query: 286 QAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIA 345
Q +LVL PTREL + V + + + + + + GG + Q + DI+IA
Sbjct: 293 QRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNRNGQIEDISKGVDIIIA 351
Query: 346 TPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATM 405
TPGRL D N S +L SI L++DEAD+MLD FE Q+++I+ RQT++ SAT
Sbjct: 352 TPGRLNDLQMN-NSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATW 410
Query: 406 TDEVKDLASVSLKNPVRIFV-NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTF-T 463
D V+ LA LK+P+ ++V N N ++Q I E ++ A+ +
Sbjct: 411 PDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNII---VTTEKEKRALTQEFVENMSPN 467
Query: 464 DHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVA 523
D V++F K A + + G+ LHGN Q+ + A+ FK I IL+ TD+
Sbjct: 468 DKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIV 527
Query: 524 ARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAK 583
+RGLD+ V V N+ P I YVHRVG R G+ G SV+L+ + + KM E++K
Sbjct: 528 SRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILD 587
Query: 584 APVKARILPQDVIL 597
++ +P+D+++
Sbjct: 588 RANQS--VPEDLVV 599
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 195 bits (496), Expect = 1e-49
Identities = 149/547 (27%), Positives = 266/547 (48%), Gaps = 53/547 (9%)
Query: 110 KKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDE 169
+K+ + + K E+ +KKRKT E S +EG+ + ++ E+
Sbjct: 72 EKKEESLTERKREQSKKKRKTMTSEIAS--------QEEGATIQWMSSVEAKIEDKKVQR 123
Query: 170 ASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPL 229
E+ +S L K ++++ K +G + Q D Q+ ++ L
Sbjct: 124 --ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLD-----QEYKINSRL 176
Query: 230 LKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPV 289
L+ I GF+ PTPIQ IPV L G+++ A A TG+GKT AF++P+L +L +
Sbjct: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKG-- 234
Query: 290 TRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAP------DIL 343
R L++ PTREL Q+H ++++ + K+ AA + P DIL
Sbjct: 235 FRALIISPTRELASQIHRELIKISEGTGFRIHMIH-----KAAVAAKKFGPKSSKKFDIL 289
Query: 344 IATPGRLIDHL-HNCPSFHLSSIEVLILDEADRMLDEY---FEEQMKEIIRMCSHHR-QT 398
+ TP RLI L + P L+S+E L++DE+D++ ++ F +Q+ I C+ H+ +
Sbjct: 290 VTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRR 349
Query: 399 MLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALL 458
+FSAT +V+ ++L N + + + + + QE + + E + + L+
Sbjct: 350 AMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFV--GSETGKLLAMRELV 407
Query: 459 TRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILV 518
+ F V++F Q+ ++A + L G+ V +H +Q QR + F+ +I +L+
Sbjct: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
Query: 519 ATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLK-- 576
T + ARG+D +GV VIN+ P + Y+HR+GRT RAG G++++ ED++ +L+
Sbjct: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
Query: 577 -EIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKR 635
+++ A PV + I F+ + K +K + K+ + E+ T K
Sbjct: 528 ANVIQQAGCPV------PEYIKGFQKLLSKQKKKMI---------KKPLERESISTTPKC 572
Query: 636 LLEKGKE 642
LEK K+
Sbjct: 573 FLEKAKD 579
>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 194 bits (493), Expect = 3e-49
Identities = 122/367 (33%), Positives = 201/367 (54%), Gaps = 18/367 (4%)
Query: 220 FQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLER 279
F+D L LL+AI GF+ P+ +Q CIP +LG D+ A +G GKTA F L L++
Sbjct: 47 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
Query: 280 LIYKPRQAPVT---RVLVLVPTRELGIQVHSVTRQLAQFC-NITTCLAVGGLDVKSQEAA 335
L PVT VLV+ TREL Q+ + +++ N+ + GGL +K E
Sbjct: 107 L------EPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEV 160
Query: 336 LRA-APDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEY-FEEQMKEIIRMCS 393
L+ P I++ TPGR++ N S +L I+ ILDE D+ML++ ++EI RM
Sbjct: 161 LKKNCPHIVVGTPGRILALARN-KSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTP 219
Query: 394 HHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPF-LRQEFIRIRPNREGDREA 452
H +Q M+FSAT++ E++ + +++P+ IFV+ T + L+Q +++++ N + +
Sbjct: 220 HEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRK-- 277
Query: 453 IVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDE 512
+ LL + V++F ++ ++ + LL +H + Q +RL ++FKD
Sbjct: 278 -LFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDF 336
Query: 513 QIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVG-EDE 571
Q ILVAT++ RG+DIE V N+ MP Y+HRV R R G G +++ V E++
Sbjct: 337 QRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEND 396
Query: 572 RKMLKEI 578
K+L ++
Sbjct: 397 AKILNDV 403
>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 194 bits (493), Expect = 3e-49
Identities = 122/367 (33%), Positives = 201/367 (54%), Gaps = 18/367 (4%)
Query: 220 FQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLER 279
F+D L LL+AI GF+ P+ +Q CIP +LG D+ A +G GKTA F L L++
Sbjct: 47 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
Query: 280 LIYKPRQAPVT---RVLVLVPTRELGIQVHSVTRQLAQFC-NITTCLAVGGLDVKSQEAA 335
L PVT VLV+ TREL Q+ + +++ N+ + GGL +K E
Sbjct: 107 L------EPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEV 160
Query: 336 LRA-APDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEY-FEEQMKEIIRMCS 393
L+ P I++ TPGR++ N S +L I+ ILDE D+ML++ ++EI RM
Sbjct: 161 LKKNCPHIVVGTPGRILALARN-KSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTP 219
Query: 394 HHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPF-LRQEFIRIRPNREGDREA 452
H +Q M+FSAT++ E++ + +++P+ IFV+ T + L+Q +++++ N + +
Sbjct: 220 HEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRK-- 277
Query: 453 IVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDE 512
+ LL + V++F ++ ++ + LL +H + Q +RL ++FKD
Sbjct: 278 -LFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDF 336
Query: 513 QIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVG-EDE 571
Q ILVAT++ RG+DIE V N+ MP Y+HRV R R G G +++ V E++
Sbjct: 337 QRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDEND 396
Query: 572 RKMLKEI 578
K+L ++
Sbjct: 397 AKILNDV 403
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,593,982
Number of Sequences: 37866
Number of extensions: 1348475
Number of successful extensions: 22939
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 427
Number of HSP's successfully gapped in prelim test: 708
Number of HSP's that attempted gapping in prelim test: 11060
Number of HSP's gapped (non-prelim): 7661
length of query: 796
length of database: 18,247,518
effective HSP length: 110
effective length of query: 686
effective length of database: 14,082,258
effective search space: 9660428988
effective search space used: 9660428988
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.