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Search of human proteins with 224589071
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224589071 BMS1-like, ribosome assembly protein [Homo
sapiens]
(1282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224589071 BMS1-like, ribosome assembly protein [Homo sapiens] 2575 0.0
gi|239758065 PREDICTED: similar to BMS1-like, ribosome assembly ... 469 e-131
gi|239743846 PREDICTED: similar to BMS1-like, ribosome assembly ... 249 2e-65
gi|239743748 PREDICTED: similar to BMS1-like, ribosome assembly ... 219 2e-56
gi|239755367 PREDICTED: similar to BMS1 homolog, ribosome assemb... 169 2e-41
gi|239744145 PREDICTED: hypothetical protein XP_002343044 [Homo ... 167 8e-41
gi|39780588 TSR1, 20S rRNA accumulation [Homo sapiens] 111 5e-24
gi|217330641 IWS1 homolog [Homo sapiens] 71 8e-12
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 64 1e-09
gi|24415404 MDN1, midasin homolog [Homo sapiens] 62 3e-09
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 60 1e-08
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 60 1e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 60 1e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 59 2e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 59 2e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 58 5e-08
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 58 5e-08
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 57 9e-08
gi|148746195 trichohyalin [Homo sapiens] 57 1e-07
gi|210032580 SET domain containing 1B [Homo sapiens] 56 2e-07
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 55 3e-07
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 55 3e-07
gi|55956788 nucleolin [Homo sapiens] 55 3e-07
gi|31982906 cingulin-like 1 [Homo sapiens] 54 7e-07
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 54 1e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 54 1e-06
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 54 1e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 52 3e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 52 3e-06
gi|221316599 chromogranin B precursor [Homo sapiens] 52 4e-06
>gi|224589071 BMS1-like, ribosome assembly protein [Homo sapiens]
Length = 1282
Score = 2575 bits (6673), Expect = 0.0
Identities = 1282/1282 (100%), Positives = 1282/1282 (100%)
Query: 1 MEAKDQKKHRKKNSGPKAAKKKKRLLQDLQLGDEEDARKRNPKAFAVQSAVRMARSFHRT 60
MEAKDQKKHRKKNSGPKAAKKKKRLLQDLQLGDEEDARKRNPKAFAVQSAVRMARSFHRT
Sbjct: 1 MEAKDQKKHRKKNSGPKAAKKKKRLLQDLQLGDEEDARKRNPKAFAVQSAVRMARSFHRT 60
Query: 61 QDLKTKKHHIPVVDRTPLEPPPIVVVVMGPPKVGKSTLIQCLIRNFTRQKLTEIRGPVTI 120
QDLKTKKHHIPVVDRTPLEPPPIVVVVMGPPKVGKSTLIQCLIRNFTRQKLTEIRGPVTI
Sbjct: 61 QDLKTKKHHIPVVDRTPLEPPPIVVVVMGPPKVGKSTLIQCLIRNFTRQKLTEIRGPVTI 120
Query: 121 VSGKKRRLTIIECGCDINMMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIM 180
VSGKKRRLTIIECGCDINMMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIM
Sbjct: 121 VSGKKRRLTIIECGCDINMMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIM 180
Query: 181 GVLTHLDSFKHNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFIT 240
GVLTHLDSFKHNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFIT
Sbjct: 181 GVLTHLDSFKHNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFIT 240
Query: 241 VMKFRPLTWQTSHPYILADRMEDLTNPEDIRTNIKCDRKVSLYGYLRGAHLKNKSQIHMP 300
VMKFRPLTWQTSHPYILADRMEDLTNPEDIRTNIKCDRKVSLYGYLRGAHLKNKSQIHMP
Sbjct: 241 VMKFRPLTWQTSHPYILADRMEDLTNPEDIRTNIKCDRKVSLYGYLRGAHLKNKSQIHMP 300
Query: 301 GVGDFAVSDISFLPDPCALPEQQKKRCLNEKEKLVYAPLSGVGGVLYDKDAVYVDLGGSH 360
GVGDFAVSDISFLPDPCALPEQQKKRCLNEKEKLVYAPLSGVGGVLYDKDAVYVDLGGSH
Sbjct: 301 GVGDFAVSDISFLPDPCALPEQQKKRCLNEKEKLVYAPLSGVGGVLYDKDAVYVDLGGSH 360
Query: 361 VFQDEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQM 420
VFQDEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQM
Sbjct: 361 VFQDEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQM 420
Query: 421 DLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAV 480
DLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAV
Sbjct: 421 DLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAV 480
Query: 481 KGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGS 540
KGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGS
Sbjct: 481 KGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGS 540
Query: 541 KAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSL 600
KAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSL
Sbjct: 541 KAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSL 600
Query: 601 SAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKE 660
SAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKE
Sbjct: 601 SAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKE 660
Query: 661 TSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQ 720
TSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQ
Sbjct: 661 TSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQ 720
Query: 721 PDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELY 780
PDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELY
Sbjct: 721 PDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELY 780
Query: 781 GDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEY 840
GDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEY
Sbjct: 781 GDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEY 840
Query: 841 DEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQN 900
DEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQN
Sbjct: 841 DEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQN 900
Query: 901 FDPHYPIILGGLGNSEGNVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIE 960
FDPHYPIILGGLGNSEGNVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIE
Sbjct: 901 FDPHYPIILGGLGNSEGNVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIE 960
Query: 961 DHNGRQRLLKYTPQHMHCGAAFWGPITPQGTGFLAIQSVSGIMPDFRIAATGVVLDLDKS 1020
DHNGRQRLLKYTPQHMHCGAAFWGPITPQGTGFLAIQSVSGIMPDFRIAATGVVLDLDKS
Sbjct: 961 DHNGRQRLLKYTPQHMHCGAAFWGPITPQGTGFLAIQSVSGIMPDFRIAATGVVLDLDKS 1020
Query: 1021 IKIVKKLKLTGFPYKIFKNTSFIKGMFNSALEVAKFEGAVIRTVSGIRGQIKKALRAPEG 1080
IKIVKKLKLTGFPYKIFKNTSFIKGMFNSALEVAKFEGAVIRTVSGIRGQIKKALRAPEG
Sbjct: 1021 IKIVKKLKLTGFPYKIFKNTSFIKGMFNSALEVAKFEGAVIRTVSGIRGQIKKALRAPEG 1080
Query: 1081 AFRASFEDKLLMSDIVFMRTWYPVSIPAFYNPVTSLLKPVGEKDTWSGMRTTGQLRLAHG 1140
AFRASFEDKLLMSDIVFMRTWYPVSIPAFYNPVTSLLKPVGEKDTWSGMRTTGQLRLAHG
Sbjct: 1081 AFRASFEDKLLMSDIVFMRTWYPVSIPAFYNPVTSLLKPVGEKDTWSGMRTTGQLRLAHG 1140
Query: 1141 VRLKANKDSLYKPILRQKKHFNSLHIPKALQKALPFKNKPKTQAKAGKVPKDRRRPAVIR 1200
VRLKANKDSLYKPILRQKKHFNSLHIPKALQKALPFKNKPKTQAKAGKVPKDRRRPAVIR
Sbjct: 1141 VRLKANKDSLYKPILRQKKHFNSLHIPKALQKALPFKNKPKTQAKAGKVPKDRRRPAVIR 1200
Query: 1201 EPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLFR 1260
EPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLFR
Sbjct: 1201 EPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLFR 1260
Query: 1261 IQGQKERRNQKSSLKGAEGQLQ 1282
IQGQKERRNQKSSLKGAEGQLQ
Sbjct: 1261 IQGQKERRNQKSSLKGAEGQLQ 1282
>gi|239758065 PREDICTED: similar to BMS1-like, ribosome assembly
protein [Homo sapiens]
Length = 331
Score = 469 bits (1206), Expect = e-131
Identities = 234/300 (78%), Positives = 245/300 (81%), Gaps = 32/300 (10%)
Query: 856 QKQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQNFDPHYPIILGGLGNS 915
++ +LNR EFEDQDDEARV YEGFRPG+YVR+EIENVPCEFVQNFDPHYPIILGGLGNS
Sbjct: 32 EQTVELNRTEFEDQDDEARVPYEGFRPGVYVRVEIENVPCEFVQNFDPHYPIILGGLGNS 91
Query: 916 EGNVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQH 975
EGNVG VQM LKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQH
Sbjct: 92 EGNVGDVQMHLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQH 151
Query: 976 MHCGAAFWGPITPQGTGFLAIQSVSGIMPDFRIAATGVVLDLDKSIKIVKKLKLTGFPYK 1035
MHCGAAFW P+TPQGTGFLAIQSVSGIMPDFRIAATGVVLDLDKSIKIVKKLK TGFPYK
Sbjct: 152 MHCGAAFWDPVTPQGTGFLAIQSVSGIMPDFRIAATGVVLDLDKSIKIVKKLKPTGFPYK 211
Query: 1036 IFKNTSFIKGMFNSALEVAKFEGAVIRTVSGIRGQIKKALRAPEGAFRASFEDKLLMSDI 1095
IFKNTSFIK + S+ E + E L SDI
Sbjct: 212 IFKNTSFIKYGYESSFE--------------------------------NVEVNYLFSDI 239
Query: 1096 VFMRTWYPVSIPAFYNPVTSLLKPVGEKDTWSGMRTTGQLRLAHGVRLKANKDSLYKPIL 1155
VF RTWYPVSIPAFYNPVTSLLKPVGEKDTWS TTGQLRL HGVRLKANKDSLYK ++
Sbjct: 240 VFTRTWYPVSIPAFYNPVTSLLKPVGEKDTWSRTWTTGQLRLTHGVRLKANKDSLYKVLV 299
>gi|239743846 PREDICTED: similar to BMS1-like, ribosome assembly
protein (yeast) [Homo sapiens]
Length = 175
Score = 249 bits (635), Expect = 2e-65
Identities = 114/126 (90%), Positives = 120/126 (95%)
Query: 858 QAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQNFDPHYPIILGGLGNSEG 917
+ +LN EFEDQDDEARVQYEGFRPGMYVR+EIENVPCEFVQNFDP YPIILGGLGNSEG
Sbjct: 49 KTRLNHVEFEDQDDEARVQYEGFRPGMYVRVEIENVPCEFVQNFDPLYPIILGGLGNSEG 108
Query: 918 NVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQHMH 977
NVG+VQMRLKKH WYKKILKS+DPIIFSVGWRRFQTI LYYIEDHNGRQRLLKYTPQH+H
Sbjct: 109 NVGHVQMRLKKHLWYKKILKSQDPIIFSVGWRRFQTILLYYIEDHNGRQRLLKYTPQHIH 168
Query: 978 CGAAFW 983
CGAAFW
Sbjct: 169 CGAAFW 174
>gi|239743748 PREDICTED: similar to BMS1-like, ribosome assembly
protein (yeast) [Homo sapiens]
Length = 166
Score = 219 bits (557), Expect = 2e-56
Identities = 104/120 (86%), Positives = 110/120 (91%), Gaps = 2/120 (1%)
Query: 856 QKQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQNFDPHYPIILGGLGNS 915
++ +LN EFEDQDDEARVQYEGFRPGMYVR+EIENVPCEFVQNFDP YPIILGGLGNS
Sbjct: 32 EQTVELNHVEFEDQDDEARVQYEGFRPGMYVRVEIENVPCEFVQNFDPLYPIILGGLGNS 91
Query: 916 EGNVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQH 975
EGNVG+VQMRLKKH WYKKILKS+DPIIFSVGWRRFQTI LYYIEDHNGRQRLLK P H
Sbjct: 92 EGNVGHVQMRLKKHLWYKKILKSQDPIIFSVGWRRFQTILLYYIEDHNGRQRLLK--PYH 149
>gi|239755367 PREDICTED: similar to BMS1 homolog, ribosome
assembly protein [Homo sapiens]
Length = 97
Score = 169 bits (428), Expect = 2e-41
Identities = 84/96 (87%), Positives = 88/96 (91%)
Query: 1 MEAKDQKKHRKKNSGPKAAKKKKRLLQDLQLGDEEDARKRNPKAFAVQSAVRMARSFHRT 60
ME KDQKK RKKNSGPK KKKKR LQDLQLGDEEDA+KRNPKAFAVQSAV MARSFHRT
Sbjct: 1 METKDQKKQRKKNSGPKDEKKKKRHLQDLQLGDEEDAQKRNPKAFAVQSAVWMARSFHRT 60
Query: 61 QDLKTKKHHIPVVDRTPLEPPPIVVVVMGPPKVGKS 96
QDLKTKKH IPVVDRTPLEPPPIVVVVMGPPK+ ++
Sbjct: 61 QDLKTKKHRIPVVDRTPLEPPPIVVVVMGPPKLERA 96
>gi|239744145 PREDICTED: hypothetical protein XP_002343044 [Homo
sapiens]
Length = 97
Score = 167 bits (422), Expect = 8e-41
Identities = 83/96 (86%), Positives = 87/96 (90%)
Query: 1 MEAKDQKKHRKKNSGPKAAKKKKRLLQDLQLGDEEDARKRNPKAFAVQSAVRMARSFHRT 60
ME KDQKK RKKNSGPK KKKKR LQDLQLGDEEDA+KRNPKAFAVQSAV MARSFHRT
Sbjct: 1 METKDQKKQRKKNSGPKDEKKKKRHLQDLQLGDEEDAQKRNPKAFAVQSAVWMARSFHRT 60
Query: 61 QDLKTKKHHIPVVDRTPLEPPPIVVVVMGPPKVGKS 96
QDLKTKKH IPVVDRTPLEPPPIVVVV GPPK+ ++
Sbjct: 61 QDLKTKKHRIPVVDRTPLEPPPIVVVVTGPPKLERA 96
>gi|39780588 TSR1, 20S rRNA accumulation [Homo sapiens]
Length = 804
Score = 111 bits (277), Expect = 5e-24
Identities = 85/350 (24%), Positives = 166/350 (47%), Gaps = 10/350 (2%)
Query: 765 DDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEESAKKK 824
++++ + + E ++ D D + + + K + E +E+ +E+D + +A+ +
Sbjct: 440 EEEEEYETMTIGESVHDDLYDKKVDEEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIR 499
Query: 825 HLDKKRKLKEMFDAEYDEGESTYFDDLK-GEMQKQAQLNRAEFEDQDDEARVQYEGFRPG 883
K R LK + +D E+ D + + Q ++ F++ +++ + EG G
Sbjct: 500 -FQKYRGLKSFRTSPWDPKENLPQDYARIFQFQNFTNTRKSIFKEVEEK---EVEGAEVG 555
Query: 884 MYVRIEIENVPCEFVQNFDPHYPIILGGLGNSEGNVGYVQMRLKKHRWYKKILKSRDPII 943
YV + + VP V+ F P+I L E + + M +++ + +K+++ +I
Sbjct: 556 WYVTLHVSEVPVSVVECFRQGTPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEELI 615
Query: 944 FSVGWRRFQTIPLYYIEDHNGRQRLLKYTPQHMHCGAAFWGPIT-PQGTGFLAIQSVSGI 1002
F G+RRF+ PL+ + +L ++ M A + PIT P + L Q +G+
Sbjct: 616 FHCGFRRFRASPLFSQHTAADKHKLQRFLTADMALVATVYAPITFPPASVLLFKQKSNGM 675
Query: 1003 MPDFRIAATGVVLDLDKSIKIVKKLKLTGFPYKIFKNTSFIKGMFNSALEVAKFEGAVIR 1062
+ ATG ++ +D ++K++ L+G P+KIF + ++ MF + +V F+ +R
Sbjct: 676 ---HSLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVLWFKPVELR 732
Query: 1063 TVSGIRGQIKKALRAPEGAFRASFEDKLLMSDIVFMRTWYPVSIPAFYNP 1112
T G RG IK+ L G + SF+ KL D V M + V Y+P
Sbjct: 733 TKWGRRGHIKEPL-GTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDP 781
Score = 69.7 bits (169), Expect = 2e-11
Identities = 96/403 (23%), Positives = 156/403 (38%), Gaps = 54/403 (13%)
Query: 136 DINMMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIMGVLTHLDSFKHNKQL 195
D+++++D+AKVAD +L L+D G++ L+ G P + + KQ+
Sbjct: 142 DLHVVLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKKQI 201
Query: 196 ---KKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFITVMKFRPLTWQTS 252
KK K ++ RF P KL L QE L R + K + L ++
Sbjct: 202 DTRKKLSKAVEKRF-----PHDKLLLLD-------TQQEAGMLLRQLANQKQQHLAFRDR 249
Query: 253 HPYILADRMEDLTNPEDIRTNIKCDRKVSLYGYLRGAHLKNKSQIHMPGVGDFAVSDISF 312
Y+ A ++ + + E+ N+ K+S GY+RG L +H+ G GDF + I
Sbjct: 250 RAYLFAHAVDFVPSEEN---NLVGTLKIS--GYVRGQTLNVNRLLHIVGYGDFQMKQIDA 304
Query: 313 LPDPCALPEQQKKRCLNEKEKLVYAPLSGVGGVLYD-KDAVYVDLGGSHVFQDEVGPTHE 371
DP L + K + + V + K + D G Q EV P
Sbjct: 305 PGDPFPLNPRGIKPQKDPDMAMEICATDAVDDMEEGLKVLMKADPGRQESLQAEVIP--- 361
Query: 372 LVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKA 431
++ + S++K E K K++ T + +
Sbjct: 362 ---------DPMEGEQTWPTEEELSEAKDFLKES--------SKVVKKVPKGTSSYQAEW 404
Query: 432 IF-GDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAE-MTDQYMAVKGIKRRKLE 489
I G G+ D+ E D+M +D +E S DE +EEEE E MT + +K++
Sbjct: 405 ILDGGSQSGGEGDEYEYDDMEHEDFMEEESQDESSEEEEEYETMTIGESVHDDLYDKKVD 464
Query: 490 LEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTA 532
E +++M LE+ E E DE D A
Sbjct: 465 EEAEAKM-----------LEKYKQERLEEMFPDEVDTPRDVAA 496
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 70.9 bits (172), Expect = 8e-12
Identities = 118/522 (22%), Positives = 197/522 (37%), Gaps = 70/522 (13%)
Query: 403 SEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSD 462
S D + G P ++++ + G D E++ +DGL G
Sbjct: 7 SGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHV 66
Query: 463 EEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEAD 522
++E +E + + + R+K E E P +DS+++ + E+EE
Sbjct: 67 TDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETR 126
Query: 523 ESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHC 582
+ + + E+ ++G + E G PA+ S+ L+KS P DS
Sbjct: 127 KLPGSD--SENEELLNGHASDSENEDVGKHPAS-DSEIEELQKS--------PASDSETE 175
Query: 583 TAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLS--------KPSQVSSGQKLGPQNF 634
A + S+ ESEE A DSENEE + ++S KP QVS + P
Sbjct: 176 DALKPQISDSESEEPPRHQA--SDSENEEPPKPRMSDSESEELPKP-QVSDSESEEPPRH 232
Query: 635 IDETSDIENLLK------EEED------YKEENNDSKETSGALKWKEDLSRKAAEAFLRQ 682
S+ E L K E ED EN + + + ED R A +
Sbjct: 233 QASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENE 292
Query: 683 QQAAPNL---------RKLIYGTVTED------NEEEDDDTLEELGGLFRVNQPDRECKH 727
+ P + + + TED E DDD+ E G + + H
Sbjct: 293 ELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKG--EDTEMQNDSFH 350
Query: 728 KADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLE 787
+D +F H D EE + + + + E + + KV + D ED E
Sbjct: 351 SDSHMDRKKF-----HSSDSEEEEHK-KQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEE 404
Query: 788 TGDVHKGKSGPNTQNED----IEKEVKEE--IDPDEEESAKKKHLDKKRKLKEMFDAEYD 841
K + + + D +K K E I D EE A K+ DKK + K++F ++ +
Sbjct: 405 KASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSE 464
Query: 842 EG--ESTYFDDLKGEMQKQAQ-----LNRAEFEDQDDEARVQ 876
G E D+ GE + + N+ + E++ E +V+
Sbjct: 465 SGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQVK 506
Score = 39.7 bits (91), Expect = 0.019
Identities = 44/195 (22%), Positives = 81/195 (41%), Gaps = 31/195 (15%)
Query: 363 QDEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDL 422
++ G E+ + S +D K S SDS+ E+ Q + ++EK+ +
Sbjct: 335 RENKGEDTEMQNDSFHSDSHMDRKKFHS-----SDSE---EEEHKKQKMDSDEDEKEGEE 386
Query: 423 NTGRMRRKAIFGD-EDES----------GDSDDEEDDEMSEDDGLENGSSDEEAEEEENA 471
R+ A+ D EDE D+DD + D +S+ G + ++EEE
Sbjct: 387 EKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGK 446
Query: 472 EMTDQYMAVKGIKRRKLEL-EEDSEMDLPAFADSDDDLERS---------SAEEGEAE-- 519
E++D+ K + E E+ + F +S D+ E E+GE +
Sbjct: 447 ELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQVK 506
Query: 520 EADESSEEEDCTAGE 534
EA++S +++ G+
Sbjct: 507 EAEDSDSDDNIKRGK 521
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 63.5 bits (153), Expect = 1e-09
Identities = 41/147 (27%), Positives = 71/147 (48%), Gaps = 4/147 (2%)
Query: 386 KMASSRVTLFSDSKPLGSEDID---NQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDS 442
K + R+ D + S+ D +G +PK +K+ L G ++K G +DE+ +
Sbjct: 201 KASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFED 260
Query: 443 DDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFA 502
D+ D E E D + +GSS + E E A+ Q KG+ + + E+SE + P
Sbjct: 261 SDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQS-DSSEESEEEKPPEE 319
Query: 503 DSDDDLERSSAEEGEAEEADESSEEED 529
D +++ E+ + E + +SSEE D
Sbjct: 320 DKEEEEEKKAPTPQEKKRRKDSSEESD 346
Score = 45.1 bits (105), Expect = 4e-04
Identities = 64/264 (24%), Positives = 96/264 (36%), Gaps = 49/264 (18%)
Query: 436 EDESGDSDDEEDDEMSE-----------DDGLENGSSDEEAEEEENAEM---TDQYMAVK 481
+D+ D D+EE ++ +D LE S +A EE + + K
Sbjct: 183 KDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAK 242
Query: 482 GIKRRKLELEEDSEMDLPAFADSDD-DLE------RSSAEEGEAEEADESSEEEDCTAGE 534
G +++K + D E AF DSDD D E S EE + ++ G
Sbjct: 243 GGRKKKKKKGSDDE----AFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGP 298
Query: 535 KGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDES 594
KG+ + E S+ P + D+ E+ KKA P +E +D S
Sbjct: 299 KGVDEQSDSSEESEEEKPP---EEDKEEEEE----KKAPTP---------QEKKRRKDSS 342
Query: 595 EESSSLSAEEEDSENEEAI--------RKKLSKPSQVSSGQKLGPQNFIDETSDIENLLK 646
EES S + DSE A+ K+ KPS SS P E + L+
Sbjct: 343 EESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLR 402
Query: 647 EEEDYKEENNDSKETSGALKWKED 670
E+ E A + + D
Sbjct: 403 AAASKLEQGKRVSEMPAAKRLRLD 426
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 62.4 bits (150), Expect = 3e-09
Identities = 123/593 (20%), Positives = 231/593 (38%), Gaps = 113/593 (19%)
Query: 404 EDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSD-------------DEEDDEM 450
E D++G + K ++ + ++GD+DE D + DEED E+
Sbjct: 4750 EKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSEL 4809
Query: 451 -SEDDGLENGSSD------EEAEEEENAEMTDQYMAVKGIKRRKLELE-EDSEMD----- 497
++DD L++G+S+ ++ EE+E AE D I + E + +++E+D
Sbjct: 4810 VAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGN 4869
Query: 498 -----LPAFADSDDDL----------ERSSAEEGEAE---EADESSEEEDCTAGEKGISG 539
P D DDL E + EEGE E E E EE A E+G
Sbjct: 4870 QEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERG--E 4927
Query: 540 SKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSS 599
++ S++ P S+ E M A EE + +S E
Sbjct: 4928 TETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKD 4987
Query: 600 LSAEE--------------------EDSENEEAIRKKLSKPSQVSSGQKLGPQNFID-ET 638
A+E EDS+ EE + + L + S GQ G +N + +
Sbjct: 4988 KEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQ-TGVENMQNTQA 5046
Query: 639 SDIENLLKEEEDYKEENN----DSKETSG------ALKWKEDLSRKAAEAFLRQQQAAPN 688
++ E+E KEE+ D+ + G A + +RK ++F R+ A N
Sbjct: 5047 MELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADN 5106
Query: 689 LRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQ-PDRECKHKADSLDCSRFLVEAPHDWDL 747
R + D+ E L + Q P ++ + + + D + + +D
Sbjct: 5107 ERSM------GDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDA 5160
Query: 748 E-------EVMNSIRDCFVTGKWEDDKDAAKVLAEDEE----LYGDFEDLETGDVHKGKS 796
+ E S +D +GK +++++ L + EE D E L+ ++ G +
Sbjct: 5161 QTYDVASKEQQQSAKD---SGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTT 5217
Query: 797 GPNTQNEDIEKEV-----KEEIDPDEEESAKKKHLDKKRKLKE-MFDAEYDEGESTYF-- 848
P +++E E+ +E+ DP +++ K+ +K + +E + T F
Sbjct: 5218 AP-LGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQP 5276
Query: 849 -----DDLKGEMQKQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCE 896
++L+ E+++Q ++ + +E +V E ++ + + + CE
Sbjct: 5277 FLKDVNELRQELERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQRLCE 5329
Score = 43.1 bits (100), Expect = 0.002
Identities = 64/270 (23%), Positives = 106/270 (39%), Gaps = 41/270 (15%)
Query: 402 GSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDD---EMSED----- 453
G +D+ +Q + +E+ + G+ + K ED SD + +D EMSED
Sbjct: 4685 GMKDVSDQ--IGNEEQVEDTFQKGQEKDK-----EDPDSKSDIKGEDNAIEMSEDFDGKM 4737
Query: 454 -DG-LENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERS 511
DG LE D+E + E ++ D++M L EE ++D + D DD+ E
Sbjct: 4738 HDGELEEQEEDDEKSDSEGGDL-DKHMG-------DLNGEEADKLDERLWGD-DDEEEDE 4788
Query: 512 SAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKK 571
E+ + EE +EED K L N D+ +K ++
Sbjct: 4789 EEEDNKTEETGPGMDEEDSELVAK------------DDNLDSGNSNKDKSQQDKKEEKEE 4836
Query: 572 AALPTFDSGHCTAEEVFASEDESE-ESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLG 630
A G E D E E +E EA+ L + S K G
Sbjct: 4837 AEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEAL--DLPDDLNLDSEDKNG 4894
Query: 631 PQNFIDETSDIENLLKEEEDYKEENNDSKE 660
++ +E + EN L+ +E +E ++++E
Sbjct: 4895 GEDTDNEEGEEENPLEIKEKPEEAGHEAEE 4924
Score = 42.0 bits (97), Expect = 0.004
Identities = 67/298 (22%), Positives = 119/298 (39%), Gaps = 35/298 (11%)
Query: 591 EDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEED 650
E + S + EE+ + + ++K K S G N I+ + D + + + E
Sbjct: 4684 EGMKDVSDQIGNEEQVEDTFQKGQEK-DKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGEL 4742
Query: 651 YKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTED-NEEEDDDTL 709
++E +D K S DL + + + A L + ++G E+ +EEE+D+
Sbjct: 4743 EEQEEDDEKSDSEG----GDLDKHMGDL---NGEEADKLDERLWGDDDEEEDEEEEDNKT 4795
Query: 710 EELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDA 769
EE G +++ D E K D+LD + EE + D G +DK
Sbjct: 4796 EETGP--GMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEAD---DGGQGEDKIN 4850
Query: 770 AKVLAEDEELYGDFEDLETGDVHKGKSG---------PNTQNEDIEKEVKEEIDPDEEES 820
++ DE D+++ E H + P+ N D E + E D D EE
Sbjct: 4851 EQI---DER---DYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGE-DTDNEEG 4903
Query: 821 AKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYE 878
++ L+ K K +E + GE+ + + Q+ E +DD+A + E
Sbjct: 4904 EEENPLEIKEKPEEAGHEAEERGETE-----TDQNESQSPQEPEEGPSEDDKAEGEEE 4956
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 60.5 bits (145), Expect = 1e-08
Identities = 62/262 (23%), Positives = 113/262 (43%), Gaps = 29/262 (11%)
Query: 363 QDEVGPTHELVQSLISTHSTIDAKMASS---RVTLFSDSKPLGSEDIDNQGLMMPKEEKQ 419
Q+E P E ++ +++ S D++ + R L + + + PKE K+
Sbjct: 1268 QNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE 1327
Query: 420 MDLNTGRMRRKAIFGDEDESG--DSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQY 477
+ GR RRK D ++S +S E+ SED+ S ++AE EEN Q
Sbjct: 1328 VK---GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQK 1384
Query: 478 MAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGI 537
KRR+++++EDS + + ++ +++ + EE E EE +E E +D
Sbjct: 1385 K-----KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD-------- 1431
Query: 538 SGSKAAGEGSK---AGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDES 594
SK+ G+G K L +++ N K ++ + + EV ED S
Sbjct: 1432 --SKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDAS 1489
Query: 595 EESSSLSAE---EEDSENEEAI 613
++ + +ED E +E +
Sbjct: 1490 PTKCPITTKLVLDEDEETKEPL 1511
Score = 52.0 bits (123), Expect = 4e-06
Identities = 90/392 (22%), Positives = 152/392 (38%), Gaps = 97/392 (24%)
Query: 378 STHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDED 437
S S+ DA+ +S D+K + ++ KE+K+ L T R++A D
Sbjct: 1113 SGSSSSDAEESSE------DNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA---DIT 1163
Query: 438 ESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMD 497
S SD E+DD+ S + GSSDE+ + +T+ + + +E
Sbjct: 1164 SSSSSDIEDDDQNS----IGEGSSDEQKIKP----VTENLVLSSHTGFCQSSGDEALSKS 1215
Query: 498 LPAFADSDDD---LERSSAEEGEAEEADES-SEEEDCTAGEKGISGSKAAGE------GS 547
+P D DDD E A++ EE + S +ED ++ ++ G K G+ G
Sbjct: 1216 VPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD 1275
Query: 548 KAGLSPANCQSDRVNLEKS-------LLMKKAALPTFDSGH------------------- 581
+ + N +SD + E LL K + +SG
Sbjct: 1276 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1335
Query: 582 --------------CTAEEVFASEDESEESSSLSAEEEDSENEEAI-----RKKLSKPSQ 622
+EEV SEDE + + + E EN+ + R+++
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1395
Query: 623 VSSGQKLGPQNFIDETSDIENLLKEEEDYKE-ENNDSK--------------------ET 661
SS K + +E + E +EEE+ +E EN+DSK ET
Sbjct: 1396 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTET 1455
Query: 662 SGALKWKEDLSRKAAEAFLRQQQAAPNLRKLI 693
ALK +E+ ++ AE +++ LR++I
Sbjct: 1456 QNALKEEEERRKRIAE----REREREKLREVI 1483
Score = 44.7 bits (104), Expect = 6e-04
Identities = 77/350 (22%), Positives = 141/350 (40%), Gaps = 43/350 (12%)
Query: 321 EQQKKRCLNEKEKLVYAPL-SGVGGVLYDKDAVYVDLGGSHVFQDEVGPTHELVQSLIST 379
+++K+ L K A + S + D D + G S + ++ P E + ++S+
Sbjct: 1144 KEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD--EQKIKPVTENL--VLSS 1199
Query: 380 HSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDES 439
H+ SS S S P+ +D D+ + K+M L + + DED S
Sbjct: 1200 HTGF---CQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKAN---LSSDEDGS 1253
Query: 440 GDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEM-TDQYMAVKGIKRRKLELEEDSEMDL 498
D + EE + + EN DEEA+ + N+E +D + K R +L + + D
Sbjct: 1254 SDDEPEEGKKRTGKQNEEN-PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG 1312
Query: 499 PAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQS 558
+ + + +G S + ED E G+S + E + + + ++
Sbjct: 1313 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1372
Query: 559 DRVNLEKSLLMKK----------AALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSE 608
+ ++S KK ++ + EE E+E EE EEE+ E
Sbjct: 1373 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE----EEEEDE 1428
Query: 609 NEEAI-----RKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKE 653
N+++ RKK+ K + KL ++ +N LKEEE+ ++
Sbjct: 1429 NDDSKSPGKGRKKIRK---ILKDDKL--------RTETQNALKEEEERRK 1467
Score = 43.5 bits (101), Expect = 0.001
Identities = 96/449 (21%), Positives = 169/449 (37%), Gaps = 61/449 (13%)
Query: 445 EEDDEMSEDDGLENGSSDEEAEEEEN-----AEMTDQYMAVKGIKRRKLELEEDSEMD-- 497
++ DE SEDD ++ EE ++ + +M QY + + E EE
Sbjct: 934 DQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKG 993
Query: 498 LPAFADSDDDLERSSAE--EGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPAN 555
+ + D E+ S + + +++ DE S+ + + G KG S + + SK G
Sbjct: 994 IKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG-KGDSCDSSEDKKSKNGAYGRE 1052
Query: 556 CQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRK 615
++ L+ K++ D E+ ED S E E K
Sbjct: 1053 -------KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSK 1105
Query: 616 KLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKA 675
+ +K Q S +SD E E+ K++ SK+ + +K K+ R +
Sbjct: 1106 RNTKEIQSGSS-----------SSDAEES-SEDNKKKKQRTSSKKKAVIVKEKK---RNS 1150
Query: 676 AEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRE----------C 725
+++QA I + + D E++D +++ E + +P E C
Sbjct: 1151 LRTSTKRKQAD------ITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFC 1204
Query: 726 KHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFED 785
+ D V D D + N I + ++ L+ DE+ D E
Sbjct: 1205 QSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLL------EEIKANLSSDEDGSSDDEP 1258
Query: 786 LETGDVHKGKSGP-NTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGE 844
E G GK N +E+ + +V E D D EES K ++ + R L+ +GE
Sbjct: 1259 -EEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRY--RHRLLRHKLTV--SDGE 1313
Query: 845 STYFDDLKGEMQKQAQ-LNRAEFEDQDDE 872
S K + K+ + NR + +D E
Sbjct: 1314 SGEEKKTKPKEHKEVKGRNRRKVSSEDSE 1342
Score = 38.5 bits (88), Expect = 0.042
Identities = 92/527 (17%), Positives = 194/527 (36%), Gaps = 77/527 (14%)
Query: 394 LFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSED 453
L D SED Q +E+K+ ++K I ++ SD E E+
Sbjct: 931 LKKDQSDETSEDDKKQSKKGTEEKKK----PSDFKKKVIKMEQQYESSSDGTEKLPEREE 986
Query: 454 --------DGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPA--FAD 503
++NG++D E + ++ + T ++K EL + +E D
Sbjct: 987 ICHFPKGIKQIKNGTTDGEKKSKKIRDKTS---------KKKDELSDYAEKSTGKGDSCD 1037
Query: 504 SDDDLERSSAEEGEAEE-----ADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQS 558
S +D + + G ++ S + +DC++ + K + G + ++ +
Sbjct: 1038 SSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK------EDGCNSSDKRL 1091
Query: 559 DRVNL-EKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEE---------DSE 608
R+ L E+ L K SG +++ +SED ++ S++++ +S
Sbjct: 1092 KRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSL 1151
Query: 609 NEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDY----------KEENNDS 658
RK+ S SS + QN I E S E +K + + +++
Sbjct: 1152 RTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEA 1211
Query: 659 KETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRV 718
S + +D E + ++ ++ + +++E ++ + G
Sbjct: 1212 LSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEE 1271
Query: 719 NQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNS------IRDCFVTGKWEDDKDAAKV 772
N D E K++ +S D D EE +R E ++
Sbjct: 1272 NPGDEEAKNQVNS----------ESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1321
Query: 773 LAEDEELYG------DFEDLETGDVHK-GKSGPNTQNEDIEKEVKEEIDPDEEESAKKKH 825
E +E+ G ED E D + G S +++ED ++ E E ++ +
Sbjct: 1322 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1381
Query: 826 LDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDE 872
KK++ + + + ++ + E +++ + E E+++DE
Sbjct: 1382 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1428
Score = 38.5 bits (88), Expect = 0.042
Identities = 87/437 (19%), Positives = 170/437 (38%), Gaps = 67/437 (15%)
Query: 456 LENGSSDEEAEE--------EENAEMTDQYMAVKGIKRRKLELE-EDSEMDLPAFADSD- 505
+++GSS +AEE ++ + + VK KR L + + D+ + + SD
Sbjct: 1111 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1170
Query: 506 DDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEK 565
+D +++S EG ++E E+ + E + D N +
Sbjct: 1171 EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPE 1230
Query: 566 SLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSS 625
+ + KK L EE+ A+ E+ SS D E EE +K+ K ++ +
Sbjct: 1231 NRIAKKMLL----------EEIKANLSSDEDGSS------DDEPEEG-KKRTGKQNEENP 1273
Query: 626 GQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQA 685
G + +N ++ SD ++ ++ Y+ K T + E+ K E ++
Sbjct: 1274 GDEEA-KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKE---HKEVK 1329
Query: 686 APNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDW 745
N RK+ +E+ +D +E G V++ + E + + S + L E +
Sbjct: 1330 GRNRRKV-------SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAE-LEENQRSY 1381
Query: 746 DLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDI 805
++ I+ ED K +E+EE + E+
Sbjct: 1382 KQKKKRRRIK------VQEDSSSENKSNSEEEE---------------------EEKEEE 1414
Query: 806 EKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAE 865
E+E +EE + +E+E+ K K RK K + D+ + + LK E +++ ++ E
Sbjct: 1415 EEEEEEEEEEEEDENDDSKSPGKGRK-KIRKILKDDKLRTETQNALKEEEERRKRIAERE 1473
Query: 866 FEDQDDEARVQYEGFRP 882
E + ++ E P
Sbjct: 1474 REREKLREVIEIEDASP 1490
Score = 35.4 bits (80), Expect = 0.35
Identities = 52/265 (19%), Positives = 94/265 (35%), Gaps = 35/265 (13%)
Query: 386 KMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMD-LNTGRMRRKAIFGDEDESGDSDD 444
K S++ ++ S K + N + KE K M + R +K I +D D+
Sbjct: 756 KGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDE 815
Query: 445 EEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADS 504
+ + ++ G +N + +E ++ RK E E S + D
Sbjct: 816 KHSKKGMDNQGHKNLKTSQEGSSDD--------------AERKQERETFSSAE--GTVDK 859
Query: 505 DDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLE 564
D + + ++A S++ D +G+ E S L + E
Sbjct: 860 DTTIMELRDRLPKKQQASASTDGVDKLSGK----------EQSFTSLEVRKVAETK---E 906
Query: 565 KSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVS 624
KS +K G E F +D+S+E+S E+D + + ++ KPS
Sbjct: 907 KSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETS-----EDDKKQSKKGTEEKKKPSDFK 961
Query: 625 SGQKLGPQNFIDETSDIENLLKEEE 649
Q + + E L + EE
Sbjct: 962 KKVIKMEQQYESSSDGTEKLPEREE 986
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 60.5 bits (145), Expect = 1e-08
Identities = 62/262 (23%), Positives = 113/262 (43%), Gaps = 29/262 (11%)
Query: 363 QDEVGPTHELVQSLISTHSTIDAKMASS---RVTLFSDSKPLGSEDIDNQGLMMPKEEKQ 419
Q+E P E ++ +++ S D++ + R L + + + PKE K+
Sbjct: 1306 QNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE 1365
Query: 420 MDLNTGRMRRKAIFGDEDESG--DSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQY 477
+ GR RRK D ++S +S E+ SED+ S ++AE EEN Q
Sbjct: 1366 VK---GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQK 1422
Query: 478 MAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGI 537
KRR+++++EDS + + ++ +++ + EE E EE +E E +D
Sbjct: 1423 K-----KRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD-------- 1469
Query: 538 SGSKAAGEGSK---AGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDES 594
SK+ G+G K L +++ N K ++ + + EV ED S
Sbjct: 1470 --SKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDAS 1527
Query: 595 EESSSLSAE---EEDSENEEAI 613
++ + +ED E +E +
Sbjct: 1528 PTKCPITTKLVLDEDEETKEPL 1549
Score = 52.0 bits (123), Expect = 4e-06
Identities = 90/392 (22%), Positives = 152/392 (38%), Gaps = 97/392 (24%)
Query: 378 STHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDED 437
S S+ DA+ +S D+K + ++ KE+K+ L T R++A D
Sbjct: 1151 SGSSSSDAEESSE------DNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA---DIT 1201
Query: 438 ESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMD 497
S SD E+DD+ S + GSSDE+ + +T+ + + +E
Sbjct: 1202 SSSSSDIEDDDQNS----IGEGSSDEQKIKP----VTENLVLSSHTGFCQSSGDEALSKS 1253
Query: 498 LPAFADSDDD---LERSSAEEGEAEEADES-SEEEDCTAGEKGISGSKAAGE------GS 547
+P D DDD E A++ EE + S +ED ++ ++ G K G+ G
Sbjct: 1254 VPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD 1313
Query: 548 KAGLSPANCQSDRVNLEKS-------LLMKKAALPTFDSGH------------------- 581
+ + N +SD + E LL K + +SG
Sbjct: 1314 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1373
Query: 582 --------------CTAEEVFASEDESEESSSLSAEEEDSENEEAI-----RKKLSKPSQ 622
+EEV SEDE + + + E EN+ + R+++
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1433
Query: 623 VSSGQKLGPQNFIDETSDIENLLKEEEDYKE-ENNDSK--------------------ET 661
SS K + +E + E +EEE+ +E EN+DSK ET
Sbjct: 1434 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTET 1493
Query: 662 SGALKWKEDLSRKAAEAFLRQQQAAPNLRKLI 693
ALK +E+ ++ AE +++ LR++I
Sbjct: 1494 QNALKEEEERRKRIAE----REREREKLREVI 1521
Score = 44.7 bits (104), Expect = 6e-04
Identities = 77/350 (22%), Positives = 141/350 (40%), Gaps = 43/350 (12%)
Query: 321 EQQKKRCLNEKEKLVYAPL-SGVGGVLYDKDAVYVDLGGSHVFQDEVGPTHELVQSLIST 379
+++K+ L K A + S + D D + G S + ++ P E + ++S+
Sbjct: 1182 KEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD--EQKIKPVTENL--VLSS 1237
Query: 380 HSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDES 439
H+ SS S S P+ +D D+ + K+M L + + DED S
Sbjct: 1238 HTGF---CQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKAN---LSSDEDGS 1291
Query: 440 GDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEM-TDQYMAVKGIKRRKLELEEDSEMDL 498
D + EE + + EN DEEA+ + N+E +D + K R +L + + D
Sbjct: 1292 SDDEPEEGKKRTGKQNEEN-PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG 1350
Query: 499 PAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQS 558
+ + + +G S + ED E G+S + E + + + ++
Sbjct: 1351 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1410
Query: 559 DRVNLEKSLLMKK----------AALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSE 608
+ ++S KK ++ + EE E+E EE EEE+ E
Sbjct: 1411 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE----EEEEDE 1466
Query: 609 NEEAI-----RKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKE 653
N+++ RKK+ K + KL ++ +N LKEEE+ ++
Sbjct: 1467 NDDSKSPGKGRKKIRK---ILKDDKL--------RTETQNALKEEEERRK 1505
Score = 43.5 bits (101), Expect = 0.001
Identities = 96/449 (21%), Positives = 169/449 (37%), Gaps = 61/449 (13%)
Query: 445 EEDDEMSEDDGLENGSSDEEAEEEEN-----AEMTDQYMAVKGIKRRKLELEEDSEMD-- 497
++ DE SEDD ++ EE ++ + +M QY + + E EE
Sbjct: 972 DQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKG 1031
Query: 498 LPAFADSDDDLERSSAE--EGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPAN 555
+ + D E+ S + + +++ DE S+ + + G KG S + + SK G
Sbjct: 1032 IKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG-KGDSCDSSEDKKSKNGAYGRE 1090
Query: 556 CQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRK 615
++ L+ K++ D E+ ED S E E K
Sbjct: 1091 -------KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSK 1143
Query: 616 KLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKA 675
+ +K Q S +SD E E+ K++ SK+ + +K K+ R +
Sbjct: 1144 RNTKEIQSGSS-----------SSDAEES-SEDNKKKKQRTSSKKKAVIVKEKK---RNS 1188
Query: 676 AEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRE----------C 725
+++QA I + + D E++D +++ E + +P E C
Sbjct: 1189 LRTSTKRKQAD------ITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFC 1242
Query: 726 KHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFED 785
+ D V D D + N I + ++ L+ DE+ D E
Sbjct: 1243 QSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLL------EEIKANLSSDEDGSSDDEP 1296
Query: 786 LETGDVHKGKSGP-NTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGE 844
E G GK N +E+ + +V E D D EES K ++ + R L+ +GE
Sbjct: 1297 -EEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRY--RHRLLRHKLTV--SDGE 1351
Query: 845 STYFDDLKGEMQKQAQ-LNRAEFEDQDDE 872
S K + K+ + NR + +D E
Sbjct: 1352 SGEEKKTKPKEHKEVKGRNRRKVSSEDSE 1380
Score = 38.5 bits (88), Expect = 0.042
Identities = 92/527 (17%), Positives = 194/527 (36%), Gaps = 77/527 (14%)
Query: 394 LFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSED 453
L D SED Q +E+K+ ++K I ++ SD E E+
Sbjct: 969 LKKDQSDETSEDDKKQSKKGTEEKKK----PSDFKKKVIKMEQQYESSSDGTEKLPEREE 1024
Query: 454 --------DGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPA--FAD 503
++NG++D E + ++ + T ++K EL + +E D
Sbjct: 1025 ICHFPKGIKQIKNGTTDGEKKSKKIRDKTS---------KKKDELSDYAEKSTGKGDSCD 1075
Query: 504 SDDDLERSSAEEGEAEE-----ADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQS 558
S +D + + G ++ S + +DC++ + K + G + ++ +
Sbjct: 1076 SSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK------EDGCNSSDKRL 1129
Query: 559 DRVNL-EKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEE---------DSE 608
R+ L E+ L K SG +++ +SED ++ S++++ +S
Sbjct: 1130 KRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSL 1189
Query: 609 NEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDY----------KEENNDS 658
RK+ S SS + QN I E S E +K + + +++
Sbjct: 1190 RTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEA 1249
Query: 659 KETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRV 718
S + +D E + ++ ++ + +++E ++ + G
Sbjct: 1250 LSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEE 1309
Query: 719 NQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNS------IRDCFVTGKWEDDKDAAKV 772
N D E K++ +S D D EE +R E ++
Sbjct: 1310 NPGDEEAKNQVNS----------ESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1359
Query: 773 LAEDEELYG------DFEDLETGDVHK-GKSGPNTQNEDIEKEVKEEIDPDEEESAKKKH 825
E +E+ G ED E D + G S +++ED ++ E E ++ +
Sbjct: 1360 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1419
Query: 826 LDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDE 872
KK++ + + + ++ + E +++ + E E+++DE
Sbjct: 1420 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1466
Score = 38.5 bits (88), Expect = 0.042
Identities = 87/437 (19%), Positives = 170/437 (38%), Gaps = 67/437 (15%)
Query: 456 LENGSSDEEAEE--------EENAEMTDQYMAVKGIKRRKLELE-EDSEMDLPAFADSD- 505
+++GSS +AEE ++ + + VK KR L + + D+ + + SD
Sbjct: 1149 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1208
Query: 506 DDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEK 565
+D +++S EG ++E E+ + E + D N +
Sbjct: 1209 EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPE 1268
Query: 566 SLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSS 625
+ + KK L EE+ A+ E+ SS D E EE +K+ K ++ +
Sbjct: 1269 NRIAKKMLL----------EEIKANLSSDEDGSS------DDEPEEG-KKRTGKQNEENP 1311
Query: 626 GQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQA 685
G + +N ++ SD ++ ++ Y+ K T + E+ K E ++
Sbjct: 1312 GDEEA-KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKE---HKEVK 1367
Query: 686 APNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDW 745
N RK+ +E+ +D +E G V++ + E + + S + L E +
Sbjct: 1368 GRNRRKV-------SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAE-LEENQRSY 1419
Query: 746 DLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDI 805
++ I+ ED K +E+EE + E+
Sbjct: 1420 KQKKKRRRIK------VQEDSSSENKSNSEEEE---------------------EEKEEE 1452
Query: 806 EKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAE 865
E+E +EE + +E+E+ K K RK K + D+ + + LK E +++ ++ E
Sbjct: 1453 EEEEEEEEEEEEDENDDSKSPGKGRK-KIRKILKDDKLRTETQNALKEEEERRKRIAERE 1511
Query: 866 FEDQDDEARVQYEGFRP 882
E + ++ E P
Sbjct: 1512 REREKLREVIEIEDASP 1528
Score = 35.4 bits (80), Expect = 0.35
Identities = 52/265 (19%), Positives = 94/265 (35%), Gaps = 35/265 (13%)
Query: 386 KMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMD-LNTGRMRRKAIFGDEDESGDSDD 444
K S++ ++ S K + N + KE K M + R +K I +D D+
Sbjct: 794 KGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDE 853
Query: 445 EEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADS 504
+ + ++ G +N + +E ++ RK E E S + D
Sbjct: 854 KHSKKGMDNQGHKNLKTSQEGSSDD--------------AERKQERETFSSAE--GTVDK 897
Query: 505 DDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLE 564
D + + ++A S++ D +G+ E S L + E
Sbjct: 898 DTTIMELRDRLPKKQQASASTDGVDKLSGK----------EQSFTSLEVRKVAETK---E 944
Query: 565 KSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVS 624
KS +K G E F +D+S+E+S E+D + + ++ KPS
Sbjct: 945 KSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETS-----EDDKKQSKKGTEEKKKPSDFK 999
Query: 625 SGQKLGPQNFIDETSDIENLLKEEE 649
Q + + E L + EE
Sbjct: 1000 KKVIKMEQQYESSSDGTEKLPEREE 1024
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 60.1 bits (144), Expect = 1e-08
Identities = 115/536 (21%), Positives = 207/536 (38%), Gaps = 107/536 (19%)
Query: 386 KMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDE------- 438
K A +V ++S GS+D D+ +PK+ K + +K +EDE
Sbjct: 125 KTAKPKVEMYS-----GSDDDDDFN-KLPKKAKG---KAQKSNKKWDGSEEDEDNSKKIK 175
Query: 439 -------SGDSDDEEDDEMSEDDGLENGSSDEEAEEEENA-EMTDQYMAVKGIKRRKLEL 490
SG+S DE D+ + G + ++ E+ E D +K + ++K E
Sbjct: 176 ERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEK 235
Query: 491 EEDSEMDLPAFADSDDDLERSSAEEGEAE--EADESSEEEDCTAGEKGISGSKAAGEGSK 548
+E D + R E+ E E + D+S ++E E+ SK +
Sbjct: 236 KERERKK----RDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVD--- 288
Query: 549 AGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSE 608
G+ PA+ +KA PT AE+ + + ++ E+E+ E
Sbjct: 289 TGVIPAS-------------EEKAETPT------AAEDDNEGDKKKKDKKKKKGEKEEKE 329
Query: 609 NEE----------AIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDS 658
E+ A+++ L+K + QK + I ++E KEEE ++E +
Sbjct: 330 KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Query: 659 KETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRV 718
K+ + KE L ++ Q++A + + E D+L + ++
Sbjct: 390 KKQKEKER-KERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYED 448
Query: 719 NQPDR-----ECKHKADSLD-CSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAA-- 770
+ + E K ++S++ C+ V + EE + + ED +DA
Sbjct: 449 KKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEP----EEEEDTEDAGLD 504
Query: 771 --KVLAEDEELYGDFEDLETGDVH-KGKSGPNTQNEDIEKEVKEEIDPDEEESAKK---- 823
+ +A DEE E +E VH + K P + E+ E+E ++E +EEE +
Sbjct: 505 DWEAMASDEET----EKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGS 560
Query: 824 ----------------KHLDKKRKLKEMFDAEYDEG-----ESTYFDDLKGEMQKQ 858
K LDKK + D+EYD E +D K ++K+
Sbjct: 561 EGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKR 616
Score = 40.4 bits (93), Expect = 0.011
Identities = 28/95 (29%), Positives = 53/95 (55%), Gaps = 9/95 (9%)
Query: 1177 KNKPKTQAKAGKVPKDRRRPAVIREPHERKILALLDALSTV-HSQKMKKAKEQRHLHNKE 1235
K K K + K K K++ + + P + + A+ +AL+ + ++ +K +E+ + E
Sbjct: 314 KKKDKKKKKGEKEEKEKEKK---KGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLE 370
Query: 1236 HFRAKQKEEEEKLKRQKDLRKKLFRIQGQKERRNQ 1270
AK+KEEE +L+++K RKK Q +KER+ +
Sbjct: 371 ELEAKRKEEE-RLEQEKRERKK----QKEKERKER 400
Score = 40.0 bits (92), Expect = 0.014
Identities = 29/130 (22%), Positives = 56/130 (43%), Gaps = 1/130 (0%)
Query: 399 KPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLEN 458
+P ED ++ GL E D T ++ + + E+ + ++EE++E ED+ E
Sbjct: 491 EPEEEEDTEDAGLD-DWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE 549
Query: 459 GSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEA 518
+E E + D+ ++ + + L+ + EM + DSDDD + +A
Sbjct: 550 EEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKA 609
Query: 519 EEADESSEEE 528
+ E E
Sbjct: 610 KRRIEKRRLE 619
Score = 37.7 bits (86), Expect = 0.071
Identities = 62/270 (22%), Positives = 109/270 (40%), Gaps = 57/270 (21%)
Query: 646 KEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEE- 704
KE+E K + KE ++D+ ++ E L Q + R+ + TE+NEEE
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKAD-RETVAVKPTENNEEEF 91
Query: 705 -----------------DDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDL 747
DD+ EEL D++ K K + + D D
Sbjct: 92 TSKDKKKKGQKGKKQSFDDNDSEEL--------EDKDSKSKKTAKPKVEMYSGSDDDDDF 143
Query: 748 EEVMNSIRDCFVTG--KW---EDDKDAAKVLAEDEELYGDFEDLETGDV----------- 791
++ + KW E+D+D +K + E + E + D
Sbjct: 144 NKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKN 203
Query: 792 HKGKSGPNTQ--NEDIEKEVK----EEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGES 845
K K GPN + NED + K + +++E +KK ++K KL+++ E +E E+
Sbjct: 204 QKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKL--KEKEELET 261
Query: 846 TYFDDLKGEMQKQAQLNRAEFEDQDDEARV 875
D K QK++Q +FE++ +++V
Sbjct: 262 GKKDQSK---QKESQ---RKFEEETVKSKV 285
Score = 32.7 bits (73), Expect = 2.3
Identities = 50/274 (18%), Positives = 100/274 (36%), Gaps = 53/274 (19%)
Query: 404 EDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDE 463
E + +G ++ K +++ R R +A G +D + E+ +
Sbjct: 399 ERLKKEGKLLTKSQRE-----ARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 453
Query: 464 EAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADE 523
++ E+ E+++ ++ + + E E P + ++D E + ++ EA +DE
Sbjct: 454 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDE 513
Query: 524 SSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCT 583
+E+ EG+K + + N E+
Sbjct: 514 ETEKV----------------EGNKVHIEV------KENPEEE----------------- 534
Query: 584 AEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIEN 643
EE E+E EES EE +SE E + + SG+ L + + +SD E
Sbjct: 535 -EEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSE- 592
Query: 644 LLKEEEDYKEENNDSKETSGALKWKEDLSRKAAE 677
Y +++ +KE K K + ++ E
Sbjct: 593 -------YDSDDDRTKEERAYDKAKRRIEKRRLE 619
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 59.3 bits (142), Expect = 2e-08
Identities = 95/478 (19%), Positives = 190/478 (39%), Gaps = 44/478 (9%)
Query: 414 PKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEM 473
P++ K + +A +++E+ + + E ++ E S EA+ E A+
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 474 TDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAG 533
+ A K K ++E+++ PA S + + + EE ++ E +S E+E+ +
Sbjct: 607 PVKEEA-KSPAEAKSPVKEEAKS--PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663
Query: 534 EKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDE 593
EK S KA + + SP ++ KS + ++A P A+ E +
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE------KAKSPVKEEAK 717
Query: 594 SEESSSLSAEEEDSENEEA---IRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEED 650
S E + +EE E+A ++++ P + S +K +D S +EE
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA---KTLDVKSPEAKTPAKEEA 774
Query: 651 YKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLE 710
+ ++ +K +E S + A++ L++ AP + + E + E
Sbjct: 775 RSPADKFPEKAKSPVK-EEVKSPEKAKSPLKEDAKAPEKE------IPKKEEVKSPVKEE 827
Query: 711 ELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTG-----KWED 765
E +V +P ++ + + +AP EE +S ++ K E+
Sbjct: 828 EKPQEVKVKEPPKKAEEE-----------KAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876
Query: 766 DKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEK-EVKEEIDPDEEESAKKK 824
K+ A ++ ++ E+ E K P + E K EVKE+ P E+ KK
Sbjct: 877 KKEPAVEKPKESKVEAKKEEAEDK-----KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK 931
Query: 825 HLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEGFRP 882
D + + AE E D + + +K + + E + ++D+ + E +P
Sbjct: 932 EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989
Score = 53.9 bits (128), Expect = 1e-06
Identities = 104/533 (19%), Positives = 203/533 (38%), Gaps = 48/533 (9%)
Query: 374 QSLISTHSTIDAKMASSRVTLFSD-----------SKPLGSEDIDNQGLMMPKEEKQMDL 422
Q L++ +D ++A+ R L + S P G I + + + ++
Sbjct: 386 QDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIK 445
Query: 423 NTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYM---- 478
+ ++ + +E EE E E + E +EE EEE AE ++
Sbjct: 446 VVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPP 505
Query: 479 ---AVKGIKRRKLELEEDS------------EMDLPAFADSDDDLERSSAEEGEAEEADE 523
A K K ++E++ E PA S + + + EE ++ +
Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 524 SSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCT 583
S E+E+ + + S KA + SPA +S KS + ++A P
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP--EKAKSPVKEEAKSPAEAKSPVK 623
Query: 584 AEEVFASEDESEESSSLSAEEEDSENEEA---IRKKLSKPSQVSSGQKLGPQNFIDETSD 640
E +E +S E + +EE E+A +++ P + S K ++ S
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP 683
Query: 641 IENLLKEEEDYK---EENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTV 697
++ K E K +E S E + + +E S + A++ ++++ P K V
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAK---SPV 740
Query: 698 TEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDC 757
E+ + + E V P+ + K ++ + E EEV + +
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP--EK 798
Query: 758 FVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNED---IEKEVKEEID 814
+ ED K K + + EE+ ++ E K K P E+ + +E+ D
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 815 PDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFE 867
+EE+ KK+ K K++E + ++ + + + K E + + ++ E E
Sbjct: 859 SKKEEAPKKE--APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE 909
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 59.3 bits (142), Expect = 2e-08
Identities = 100/470 (21%), Positives = 183/470 (38%), Gaps = 41/470 (8%)
Query: 444 DEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEED--------SE 495
DEE + E +G E+ + EE+ E ++ + V G ++ K E+ D SE
Sbjct: 581 DEEVEIPEEKEGAEDSKGN--GIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSE 638
Query: 496 MDLPAFADSDDDLER---SSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLS 552
+ +++D E + EEG + EE + +KG + GEG K
Sbjct: 639 GKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAE 698
Query: 553 PANCQS----DRVNLEKSLLMKKAALPTFDSG----HCTAEEVFASEDESEESSSLSAEE 604
+ ++ E+ +K + G H EE +E EE EE
Sbjct: 699 KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEE 758
Query: 605 EDSEN-------EEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENND 657
+ E EE RKK + + G++ G Q +E ++EE + E +
Sbjct: 759 GEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE 818
Query: 658 SKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEE-EDDDTLEELGGLF 716
+E G + +E+ E +++ + G E+ EE E ++ EE G
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878
Query: 717 RVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAED 776
+ + E + + + E EE + GK E++ + + E+
Sbjct: 879 EEEEGEGEGEEEGEGEGEE----EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 777 EELYGDFEDLE-TGDVHKGK------SGPNTQNEDIEKEVKE-EIDPDEEESAKKKHLDK 828
EE G+ ED E G+ +G+ G E+ E E +E E + +EEE + ++
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEE 994
Query: 829 KRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYE 878
+ E +EGE ++ +GE++ + + E E +++E + E
Sbjct: 995 GEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE 1044
Score = 52.0 bits (123), Expect = 4e-06
Identities = 89/427 (20%), Positives = 163/427 (38%), Gaps = 21/427 (4%)
Query: 435 DEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDS 494
+E E G+ D + +G + + EE ++ + E + K R E+EE
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731
Query: 495 EMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKG-ISGSKAAGEGSKAGLSP 553
E + + + D E +EGE +E E E E E+G + AG+ K
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG 791
Query: 554 ANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDE-SEESSSLSAEEEDSENEEA 612
+ + E K+ + G EV + E EE EEE+ E EE
Sbjct: 792 DQGEGEEEETEGRGEEKE------EGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEE 845
Query: 613 IRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLS 672
+ + + G++ G + +E + EEE+ + E + E G + E
Sbjct: 846 EGEGEEEEGE-GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEG 904
Query: 673 RKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSL 732
+ E +++ + E EEE + E+ G + + E + +
Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG 964
Query: 733 DCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAE-DEELYGDFEDLETGDV 791
+ E + + E + G+ E+ ++ + E +EE G+ E+ E G+V
Sbjct: 965 EGEE---EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021
Query: 792 HKGKSGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDL 851
G + E E+E +EE EE K+ ++ R+ +E E +E E Y +
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEE----GEEREKEGEGEENRRNRE----EEEEEEGKYQETG 1073
Query: 852 KGEMQKQ 858
+ E ++Q
Sbjct: 1074 EEENERQ 1080
Score = 49.3 bits (116), Expect = 2e-05
Identities = 91/425 (21%), Positives = 155/425 (36%), Gaps = 48/425 (11%)
Query: 415 KEEKQMDLNTGRMRRKAIF-GDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEM 473
+E+K+ + + R + + G E+E G+ ++EE D E++ + G EE E EE
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEE--KEGEGKEEGEGEE---- 763
Query: 474 TDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAG 533
V+G +R K E E E ER+ EE EE D+ EE+ T G
Sbjct: 764 ------VEG-EREKEEGERKKE-------------ERAGKEEKGEEEGDQGEGEEEETEG 803
Query: 534 ---EKGISGSKAAGEGSKA-GLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFA 589
EK G GE + G + E+ ++ + G EE
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGE 863
Query: 590 SEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEE 649
+ EE E E+ E E ++ + G+ G + E + E K EE
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923
Query: 650 DYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTL 709
+ +E + +E G + ++ E G + EE + +
Sbjct: 924 EGEEGEGEGEEEEGEGEGEDGEGEGEEEE----------------GEWEGEEEEGEGEGE 967
Query: 710 EELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDA 769
EE G + + E + + E + + EE + G+ E + +
Sbjct: 968 EEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG 1027
Query: 770 AKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVK-EEIDPDEEESAKKKHLDK 828
+ E EE G+ E E +G+ + E+ E+E K +E +E E + K
Sbjct: 1028 EEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKK 1087
Query: 829 KRKLK 833
K+K
Sbjct: 1088 VSKIK 1092
Score = 47.4 bits (111), Expect = 9e-05
Identities = 96/458 (20%), Positives = 179/458 (39%), Gaps = 43/458 (9%)
Query: 449 EMSEDDGL-ENGSSDE--EAEEEENAEMTDQYMAVKGIKRRK----LELEEDSEMDLPAF 501
E+++D L EN SDE E E + + Q+++ +GI + +E D E+++P
Sbjct: 531 ELTQDTALTENDDSDEYEEMSEMKEGKACKQHVS-QGIFMTQPATTIEAFSDEEVEIPEE 589
Query: 502 ADSDDDLERSSAEEGEAEEADE---------------SSEEEDCTAGEKGISGSKAAGEG 546
+ +D + + EE E E +E S + D +G + S E
Sbjct: 590 KEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAED 649
Query: 547 SKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSL----SA 602
G C+ E ++ D G E E E E
Sbjct: 650 GPEGRGDGTCEEGSSGAE-HWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGE 708
Query: 603 EEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETS 662
E+E E E+ +K+ ++ + ++ G +E D E ++E + KEE + +E
Sbjct: 709 EQEQKEREQGHQKERNQEMEEGGEEEHGEGE--EEEGDREEEEEKEGEGKEE-GEGEEVE 765
Query: 663 GALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPD 722
G + +E +K A ++ + TE EE ++ E GG + +
Sbjct: 766 GEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE 825
Query: 723 RECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGD 782
RE + + + + + EE + GK E++ + + E EE G+
Sbjct: 826 REEEEEEGEGE--------EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 783 FEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPD-EEESAKKKHLDKKRKLKEMFDAEYD 841
E+ E + + + E+ E E +EE + + EEE + K ++ + + + E
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937
Query: 842 EGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEG 879
EGE +D +GE +++ E E+ + E + EG
Sbjct: 938 EGEG---EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972
Score = 42.0 bits (97), Expect = 0.004
Identities = 46/205 (22%), Positives = 76/205 (37%), Gaps = 18/205 (8%)
Query: 434 GDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEE--------ENAEMTDQYMAVKGIKR 485
G+E+ G+ ++EE + E++G E EE E E E E ++ +
Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963
Query: 486 RKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGE 545
+ E E + E + +++ E EE EE +E E E+ GE G + E
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGE-GEEEEEGEVE 1022
Query: 546 GSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEE 605
G G + E+ +K EE + +E EE E
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEG---------EGEENRRNREEEEEEEGKYQETG 1073
Query: 606 DSENEEAIRKKLSKPSQVSSGQKLG 630
+ ENE ++ K S++ K G
Sbjct: 1074 EEENERQDGEEYKKVSKIKGSVKYG 1098
Score = 41.2 bits (95), Expect = 0.006
Identities = 65/337 (19%), Positives = 116/337 (34%), Gaps = 17/337 (5%)
Query: 402 GSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDE-----MSEDDGL 456
G E+ + + + +E+++ + K G+E+ +EE+ E E +
Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814
Query: 457 ENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEG 516
E G +E E E E + +G + E+ E + + ++ EEG
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEG 874
Query: 517 EAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLE------KSLLMK 570
E E +E E E GE + GEG + G + E + +
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 571 KAALPTFDSGHCTAEEVFAS-EDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKL 629
+ + G EE E E EE EE + E EE + G+
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEG-----EGEGEEEEGEGE 989
Query: 630 GPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNL 689
G + +E + E +EE + + E + E G ++ +E E + +
Sbjct: 990 GEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049
Query: 690 RKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECK 726
+ + EEE++ +E G Q E K
Sbjct: 1050 GEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYK 1086
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 58.2 bits (139), Expect = 5e-08
Identities = 85/429 (19%), Positives = 167/429 (38%), Gaps = 58/429 (13%)
Query: 425 GRMRRKAIFGDEDESGDSDDEEDDEMSEDDG-------LENGSSDEEAEEE-ENAEMTDQ 476
G R G +D+ D DD DD +DD E G+S ++E+ ++ +
Sbjct: 89 GGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASE 148
Query: 477 YMAVKGIKRRKLELEEDSEMDLPAFADS----DDDLERSSAEE-------------GEAE 519
A +G + E E+D DS D + S +EE G+
Sbjct: 149 ESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGS 208
Query: 520 EADE---SSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPT 576
E D+ S++ + E+G S +AG SK + Q++ + S L++ +
Sbjct: 209 ELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSE-QANTQDSGGSQLLEHPSRKI 267
Query: 577 FDSGHCTAEEVFASEDESEESSSLSAEEEDS-ENEEAIRKKLSKPSQVSSGQKLGPQNFI 635
F + E+ E ++++++ + DS EN + LS+P + S G
Sbjct: 268 FRKSRISEED---DRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKG--------- 315
Query: 636 DETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYG 695
D D + L +EE + S+ + A ++ S ++ E + + + Y
Sbjct: 316 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYV 375
Query: 696 TVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWD--LEEVMNS 753
ED++ ++D+ L ++ ++ ++SL+ S E+P D + +E + S
Sbjct: 376 EDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQS 435
Query: 754 IRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEI 813
++ ++ EE + + +D ++ D + K N+ E ++
Sbjct: 436 --------------HSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQL 481
Query: 814 DPDEEESAK 822
E ES K
Sbjct: 482 KNIEIESRK 490
Score = 45.4 bits (106), Expect = 3e-04
Identities = 88/391 (22%), Positives = 149/391 (38%), Gaps = 80/391 (20%)
Query: 340 SGVGGVLYDKDAVYVDLGGSHVFQDEVGP----THELVQSLISTHSTIDAKMASSRVTLF 395
+G GG DKD D G D+ GP E S + + D + +S
Sbjct: 95 TGKGGD--DKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASE---- 148
Query: 396 SDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDE-----EDDEM 450
+S P G + + E +++D N R+ K GD + +S++ D E
Sbjct: 149 -ESAPQGQDSAQDT----TSESRELD-NEDRVDSKPEGGDSTQESESEEHWVGGGSDGES 202
Query: 451 SEDDGLENGSSDEEAEEEEN--AEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDL 508
S DG E ++++ E+ +E + M G+K + E E+SE + L
Sbjct: 203 SHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSK--ESGENSEQANTQDSGGSQLL 260
Query: 509 ERSS---------AEEGEAEEADESSEEEDCTAGEKGISGSKAAG-------------EG 546
E S +EE + E D+++ E+ + S S+ G E
Sbjct: 261 EHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQED 320
Query: 547 SKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASE--------------- 591
SK LS +S V+ S ++A L + ++ + EEV +
Sbjct: 321 SKENLSQE--ESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQ 378
Query: 592 ---DESEESSSLSA---------EEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETS 639
D SEE SS + E+ DSE+ E++ P + +S
Sbjct: 379 EDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSS 438
Query: 640 DIENLLKEEEDYKEENNDSKETSGALKWKED 670
E+ EE +E+++DS+++S + KED
Sbjct: 439 SAES-QSEESHSEEDDSDSQDSS---RSKED 465
Score = 41.6 bits (96), Expect = 0.005
Identities = 86/458 (18%), Positives = 162/458 (35%), Gaps = 55/458 (12%)
Query: 438 ESGDSDDEEDDE----MSEDDGLENGSSDE----EAEEEENAEMTDQYMAVKGIKRRKLE 489
++ +S+D E+ + + LE+ S E +EE+ N + +D + +G
Sbjct: 23 QNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEG------- 75
Query: 490 LEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKA 549
L D + A RS+ + G+ ++ DE +D + G K EG +
Sbjct: 76 LGSDDHQYIYRLAGG---FSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNS 132
Query: 550 GLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSEN 609
L D + + ++A DS T E ++E S + E+
Sbjct: 133 RLGSDEDSDDTIQASE-----ESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQES 187
Query: 610 EEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEE-EDYKEENNDSKETSGALKWK 668
E S+ V G + D E + ++ E + E +S+ S +K K
Sbjct: 188 E-------SEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSK 240
Query: 669 ED-------LSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQP 721
E ++ + + L + + RK + +E +D++T+EE+ N
Sbjct: 241 ESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSN 300
Query: 722 DRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYG 781
R+ L R + D +E ++ V G + A + +++
Sbjct: 301 SRDT-----GLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSES 355
Query: 782 DFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAE-- 839
E V G N E +E+ D EE+S+ K +E D+E
Sbjct: 356 QEE------VVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS 409
Query: 840 ----YDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEA 873
+ E +D Q+ Q + + E Q +E+
Sbjct: 410 ESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEES 447
Score = 39.3 bits (90), Expect = 0.024
Identities = 39/198 (19%), Positives = 75/198 (37%), Gaps = 20/198 (10%)
Query: 364 DEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDI---DNQGLMMPKEEKQM 420
D+ E+ ++ D ++ R DS+ E++ ++Q + P E
Sbjct: 283 DDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQ 342
Query: 421 DLNTGRMRRKAIFGDE---DESGDS--------DDEEDDEMSEDDGLE--NGSSDEEAEE 467
+ N + +E + GD+ +D+ED + SE+D + S E EE
Sbjct: 343 EANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREE 402
Query: 468 EENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEE 527
+ ++E ++ E ED S S +EE +EE D S++
Sbjct: 403 QADSESSESL----NFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD 458
Query: 528 EDCTAGEKGISGSKAAGE 545
+ + + SK++ E
Sbjct: 459 SSRSKEDSNSTESKSSSE 476
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 58.2 bits (139), Expect = 5e-08
Identities = 85/429 (19%), Positives = 167/429 (38%), Gaps = 58/429 (13%)
Query: 425 GRMRRKAIFGDEDESGDSDDEEDDEMSEDDG-------LENGSSDEEAEEE-ENAEMTDQ 476
G R G +D+ D DD DD +DD E G+S ++E+ ++ +
Sbjct: 73 GGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASE 132
Query: 477 YMAVKGIKRRKLELEEDSEMDLPAFADS----DDDLERSSAEE-------------GEAE 519
A +G + E E+D DS D + S +EE G+
Sbjct: 133 ESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGS 192
Query: 520 EADE---SSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPT 576
E D+ S++ + E+G S +AG SK + Q++ + S L++ +
Sbjct: 193 ELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSE-QANTQDSGGSQLLEHPSRKI 251
Query: 577 FDSGHCTAEEVFASEDESEESSSLSAEEEDS-ENEEAIRKKLSKPSQVSSGQKLGPQNFI 635
F + E+ E ++++++ + DS EN + LS+P + S G
Sbjct: 252 FRKSRISEED---DRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKG--------- 299
Query: 636 DETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYG 695
D D + L +EE + S+ + A ++ S ++ E + + + Y
Sbjct: 300 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYV 359
Query: 696 TVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWD--LEEVMNS 753
ED++ ++D+ L ++ ++ ++SL+ S E+P D + +E + S
Sbjct: 360 EDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQS 419
Query: 754 IRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEI 813
++ ++ EE + + +D ++ D + K N+ E ++
Sbjct: 420 --------------HSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQL 465
Query: 814 DPDEEESAK 822
E ES K
Sbjct: 466 KNIEIESRK 474
Score = 45.4 bits (106), Expect = 3e-04
Identities = 88/391 (22%), Positives = 149/391 (38%), Gaps = 80/391 (20%)
Query: 340 SGVGGVLYDKDAVYVDLGGSHVFQDEVGP----THELVQSLISTHSTIDAKMASSRVTLF 395
+G GG DKD D G D+ GP E S + + D + +S
Sbjct: 79 TGKGGD--DKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASE---- 132
Query: 396 SDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDE-----EDDEM 450
+S P G + + E +++D N R+ K GD + +S++ D E
Sbjct: 133 -ESAPQGQDSAQDT----TSESRELD-NEDRVDSKPEGGDSTQESESEEHWVGGGSDGES 186
Query: 451 SEDDGLENGSSDEEAEEEEN--AEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDL 508
S DG E ++++ E+ +E + M G+K + E E+SE + L
Sbjct: 187 SHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSK--ESGENSEQANTQDSGGSQLL 244
Query: 509 ERSS---------AEEGEAEEADESSEEEDCTAGEKGISGSKAAG-------------EG 546
E S +EE + E D+++ E+ + S S+ G E
Sbjct: 245 EHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQED 304
Query: 547 SKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASE--------------- 591
SK LS +S V+ S ++A L + ++ + EEV +
Sbjct: 305 SKENLSQE--ESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQ 362
Query: 592 ---DESEESSSLSA---------EEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETS 639
D SEE SS + E+ DSE+ E++ P + +S
Sbjct: 363 EDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSS 422
Query: 640 DIENLLKEEEDYKEENNDSKETSGALKWKED 670
E+ EE +E+++DS+++S + KED
Sbjct: 423 SAES-QSEESHSEEDDSDSQDSS---RSKED 449
Score = 39.3 bits (90), Expect = 0.024
Identities = 39/198 (19%), Positives = 75/198 (37%), Gaps = 20/198 (10%)
Query: 364 DEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDI---DNQGLMMPKEEKQM 420
D+ E+ ++ D ++ R DS+ E++ ++Q + P E
Sbjct: 267 DDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQ 326
Query: 421 DLNTGRMRRKAIFGDE---DESGDS--------DDEEDDEMSEDDGLE--NGSSDEEAEE 467
+ N + +E + GD+ +D+ED + SE+D + S E EE
Sbjct: 327 EANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREE 386
Query: 468 EENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEE 527
+ ++E ++ E ED S S +EE +EE D S++
Sbjct: 387 QADSESSESL----NFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD 442
Query: 528 EDCTAGEKGISGSKAAGE 545
+ + + SK++ E
Sbjct: 443 SSRSKEDSNSTESKSSSE 460
Score = 38.5 bits (88), Expect = 0.042
Identities = 71/378 (18%), Positives = 132/378 (34%), Gaps = 37/378 (9%)
Query: 510 RSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLM 569
RS+ + G+ ++ DE +D + G K EG + L D + +
Sbjct: 77 RSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASE---- 132
Query: 570 KKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKL 629
++A DS T E ++E S + E+E S+ V G
Sbjct: 133 -ESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESE-------SEEHWVGGGSDG 184
Query: 630 GPQNFIDETSDIENLLKEE-EDYKEENNDSKETSGALKWKED-------LSRKAAEAFLR 681
+ D E + ++ E + E +S+ S +K KE ++ + + L
Sbjct: 185 ESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLL 244
Query: 682 QQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEA 741
+ + RK + +E +D++T+EE+ N R+ L R +
Sbjct: 245 EHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDT-----GLSQPRRDSKG 299
Query: 742 PHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQ 801
D +E ++ V G + A + +++ E V G N
Sbjct: 300 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEE------VVSESRGDNPD 353
Query: 802 NEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAE------YDEGESTYFDDLKGEM 855
E +E+ D EE+S+ K +E D+E + E +D
Sbjct: 354 PTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSS 413
Query: 856 QKQAQLNRAEFEDQDDEA 873
Q+ Q + + E Q +E+
Sbjct: 414 QEGLQSHSSSAESQSEES 431
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 57.4 bits (137), Expect = 9e-08
Identities = 54/190 (28%), Positives = 83/190 (43%), Gaps = 27/190 (14%)
Query: 430 KAIFGDEDESGDSDDEED-DEMSEDDGLE-NGSSDEEAEEEENAEMTDQYMAVKGIKRRK 487
KA DE DSD ED DE ED+G E + +DE +E+E E +G + +
Sbjct: 81 KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE--------EGDREEE 132
Query: 488 LELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGS 547
E+EE+ E D D+D E EE E EE +E EEE+ + ++ +
Sbjct: 133 EEIEEEDE-------DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTE 185
Query: 548 KAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLS-AEEED 606
K D N E + A + G + + + ESE +S+ S + E+D
Sbjct: 186 K---------DDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDD 236
Query: 607 SENEEAIRKK 616
S+ E + +K
Sbjct: 237 SDKNENLGRK 246
Score = 37.7 bits (86), Expect = 0.071
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query: 764 EDDKDAAKVLAEDEELYGDFED---LETGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEES 820
ED+ + EDEE GD E+ +E D + G + ++E+ E+E +EE +EEE
Sbjct: 112 EDNDEPGDEDEEDEE--GDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE---EEEEE 166
Query: 821 AKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEF-EDQDDEARVQYE 878
+ H + M D E D+ + +D+ E+ ++ LN + ED AR + E
Sbjct: 167 ENEDHQMNCHNTRIMQDTEKDDNNNDEYDNY-DELVAKSLLNLGKIAEDAAYRARTESE 224
Score = 36.6 bits (83), Expect = 0.16
Identities = 58/226 (25%), Positives = 90/226 (39%), Gaps = 39/226 (17%)
Query: 403 SEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEE-DDEMSEDDGLENGSS 461
SED D G +E + D R + I +EDE D D E+ +DE E+
Sbjct: 111 SEDNDEPG-----DEDEEDEEGDREEEEEI-EEEDEDDDEDGEDVEDEEEEE-------- 156
Query: 462 DEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSS------AEE 515
+EE EEEE E D M + + ++D+ D D+ D+L S E
Sbjct: 157 EEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNND---EYDNYDELVAKSLLNLGKIAE 213
Query: 516 GEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKA-AL 574
A A SE T+ K G K+ LS ++L+ ++ + +L
Sbjct: 214 DAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELS--------LDLDSDVVRETVDSL 265
Query: 575 PTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKP 620
GH V SE+ ++ + + S ++DS N + L KP
Sbjct: 266 KLLAQGH----GVVLSENMNDRNYADSMSQQDSRNMNYV--MLGKP 305
Score = 35.0 bits (79), Expect = 0.46
Identities = 60/264 (22%), Positives = 106/264 (40%), Gaps = 44/264 (16%)
Query: 591 EDESEESSSLSAE--EEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEE 648
EDE EE S + E +ED E+EE R++ + + ++ DE + E +EE
Sbjct: 104 EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEE--EEE 161
Query: 649 EDYKEENNDSKETSGALKWKEDLSRK-------------AAEAFLR----QQQAAPNLR- 690
E+ +EEN D + + +D + A++ L + AA R
Sbjct: 162 EEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRART 221
Query: 691 KLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEV 750
+ + T ++ E+D D E LG ++ D + +++D + L + H L E
Sbjct: 222 ESEMNSNTSNSLEDDSDKNENLGRKSELSL-DLDSDVVRETVDSLKLLAQG-HGVVLSEN 279
Query: 751 MNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVK 810
MN D++ A +++ + ++ V GK N E + +E
Sbjct: 280 MN-------------DRNYADSMSQQDSRNMNY-------VMLGKPMNNGLMEKMVEESD 319
Query: 811 EEIDPDEEESAKKKHLDKKRKLKE 834
EE+ E + + D RKL E
Sbjct: 320 EEVCLSSLECLRNQCFDLARKLSE 343
Score = 33.1 bits (74), Expect = 1.8
Identities = 37/193 (19%), Positives = 73/193 (37%), Gaps = 29/193 (15%)
Query: 592 DESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDY 651
D+S+ + + +EED E + + G ++ DE D E + EE+
Sbjct: 91 DDSDGTEDMDEKEEDEGEEYS-----------EDNDEPGDEDEEDEEGDREEEEEIEEED 139
Query: 652 KEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEE 711
++++ D ++ + +E+ + E Q + +++ T +DN ++ D +E
Sbjct: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
Query: 712 LGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAK 771
L L+ + +A + E MNS + EDD D +
Sbjct: 200 LVA--------------KSLLNLGKIAEDAAYRARTESEMNS----NTSNSLEDDSDKNE 241
Query: 772 VLAEDEELYGDFE 784
L EL D +
Sbjct: 242 NLGRKSELSLDLD 254
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 57.0 bits (136), Expect = 1e-07
Identities = 94/480 (19%), Positives = 189/480 (39%), Gaps = 69/480 (14%)
Query: 409 QGLMMPKEEKQMDLNTGRMRRKAI-FGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEE 467
Q + +EEK+ R R K + F +E+E + E+DGL+ ++E
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Query: 468 EENAEMTDQYMAVKGIKRR-----KLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEAD 522
+ + + + +RR K L+E + + +++L+R E+ +E +
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 523 ESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHC 582
EE+ E+ E K Q + +K L K+ L
Sbjct: 928 RQYREEEQLQQEE---EQLLREEREKRRRQERERQYRK---DKKLQQKEEQL-------- 973
Query: 583 TAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIE 642
EE + E EE E E+ +R++ K + ++ ++ + + + E
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ--EEE 1031
Query: 643 NLLKEEED---YKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTE 699
LL+EE + +E +E + +E L + E R+Q+ RK E
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERET-RRRQELERQYRK------EE 1084
Query: 700 DNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFV 759
+ ++E++ L E R + +R+C+ + + ++ + L E R
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEE--------LQQEEEQLLREEREKRR---- 1132
Query: 760 TGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEID-PDEE 818
++ + E+EE+ + E L + K + +++E++ +EE + EE
Sbjct: 1133 ------RQELERQYREEEEVQQEEEQLLREEPEK------RRRQELERQYREEEELQQEE 1180
Query: 819 ESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYE 878
E ++ +K+R+ +E +Y E E E+Q+Q + R EDQ + + Q+E
Sbjct: 1181 EQLLREEQEKRRQERE---RQYREEE---------ELQRQKRKQRYRDEDQRSDLKWQWE 1228
Score = 40.0 bits (92), Expect = 0.014
Identities = 101/494 (20%), Positives = 185/494 (37%), Gaps = 66/494 (13%)
Query: 391 RVTLFSDSKPLGSEDI--DNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDD 448
R TL++ KP E + + Q L +EE Q + R R +++ +EE
Sbjct: 886 RHTLYA--KPALQEQLRKEQQLLQEEEEELQREEREKRRR-------QEQERQYREEEQL 936
Query: 449 EMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDL 508
+ E+ L EE E+ E QY K +KL+ +E+ + +
Sbjct: 937 QQEEEQLLR-----EEREKRRRQERERQYR-----KDKKLQQKEEQ------LLGEEPEK 980
Query: 509 ERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGE---GSKAGLSPANCQSDRVNLEK 565
R E + E +E +EE+ E+ + E K L Q R EK
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Query: 566 SLLMKKAALPTFDSGHCTAEEVFASEDE-SEESSSLSAEEEDSENEEAIRKKLSKPS--Q 622
L ++ E + E+E +E L EE ++ + + ++ K Q
Sbjct: 1041 RRLQER-------------ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 623 VSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQ 682
Q L + + E +EEE+ ++E + +++L R+ E Q
Sbjct: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147
Query: 683 QQAAPNLRKLIYGTVTEDNE---EEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLV 739
Q+ LR+ ++ E E+++ +E L R Q R + + R
Sbjct: 1148 QEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ----YREEE 1203
Query: 740 EAPHDWDLEEVMNSIRDCFVTGKWEDDKDAA----KVLAEDEELYGDFEDLETGDVHKGK 795
E + + + + +WE +K+ A KV + E F LE + +
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE-NEQFRQLEDSQLRDRQ 1262
Query: 796 SGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEM 855
S +D++ + E+ + D E+ +++ + R E E +E + D K
Sbjct: 1263 S-----QQDLQHLLGEQQERDREQE-RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS-- 1314
Query: 856 QKQAQLNRAEFEDQ 869
Q++ QL R E E++
Sbjct: 1315 QEEKQLLREEREEK 1328
Score = 39.3 bits (90), Expect = 0.024
Identities = 30/127 (23%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
Query: 1156 RQKKHFNSLHIPKALQKALPFKNKPKTQAKAGKVPKDRRRPAVIREPHERKILALLDALS 1215
+Q + L + L++ + + + + K ++RR + RE ER+ + +
Sbjct: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Query: 1216 TVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLFRIQGQKERRNQKSSLK 1275
H Q+ +K + +R + R + EEEE+ ++Q+ ++L R Q+ERR Q+ +
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR--EQEERREQRLKRQ 522
Query: 1276 GAEGQLQ 1282
E +LQ
Sbjct: 523 EEEERLQ 529
Score = 37.7 bits (86), Expect = 0.071
Identities = 28/91 (30%), Positives = 53/91 (58%), Gaps = 8/91 (8%)
Query: 1188 KVPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQR---HLHNKEHFRAKQKE- 1243
++ ++RR + RE ER+ LL Q++K+ +E+R L +E R +Q+E
Sbjct: 557 RLEQERREQRLKREQEERRD-QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
Query: 1244 EEEKLKR---QKDLRKKLFRIQGQKERRNQK 1271
E++LKR +++ R++L + + Q+ERR Q+
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Score = 35.0 bits (79), Expect = 0.46
Identities = 84/462 (18%), Positives = 170/462 (36%), Gaps = 64/462 (13%)
Query: 436 EDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSE 495
E+E G ++ E E +E++E++E E D+ + + R++ E +E E
Sbjct: 130 EEEPGQRRRQKRQEQER----ELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185
Query: 496 MDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPAN 555
E + + E +E +EE E + +G +
Sbjct: 186 RRA----------EEEQLQSCKGHETEEFPDEEQLRRREL----LELRRKGREEKQQQRR 231
Query: 556 CQSDRV---NLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEA 612
+ DRV EK ++ L EE E+E + L EEE E
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVL--------RKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 613 IRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEE-DYKEENNDSKETSGALKWKEDL 671
+ + + Q+L + + + E ++EE ++E + +E + + +
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ 343
Query: 672 SRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADS 731
+ + R+Q+ ++L E EE + L L R Q RE + + +
Sbjct: 344 EERREQQLRREQEEERREQQL----RREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
Query: 732 LDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDV 791
+ + L R+ + L +++L + E+ +
Sbjct: 400 --------QLRREQQLRREQQLRRE--------------QQLRREQQLRREQEE----ER 433
Query: 792 HKGKSGPNTQNEDIEKEVKEEID--PDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFD 849
H+ K + + +++E +E D EEE+ + + +K++LK + E E +
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE 493
Query: 850 DLKGEMQ--KQAQLNRAEFEDQDDEARVQYEGFRPGMYVRIE 889
+ + E Q ++ QL R + E ++ + Q E R +R E
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Score = 34.7 bits (78), Expect = 0.60
Identities = 81/487 (16%), Positives = 186/487 (38%), Gaps = 46/487 (9%)
Query: 413 MPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEA---EEEE 469
+ +EE+Q+ RR+ + + +E++++ ++ + + E EEEE
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 470 NAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEED 529
+ +Q + + KRR+ ELE + ++ L R E+ E + EEE+
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREE-EELQQEEEQLLREEQEKRRQERERQYREEEE 1204
Query: 530 CTAGEKGISGSKAAGEGSKAGLS-PANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVF 588
++ + E ++ L + + + + K F +
Sbjct: 1205 LQRQKRK---QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ---LEDSQL 1258
Query: 589 ASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFID------ETSDIE 642
++ L E+++ + E+ R+ + ++L + + ++ + +
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK 1318
Query: 643 NLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNE 702
LL+EE +EE +ET + +E L ++ E LR+Q+ R+ E
Sbjct: 1319 QLLREE---REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE------EELRH 1369
Query: 703 EEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDL------EEVMNSIRD 756
+E E R + +R+ + L C + D D +++ RD
Sbjct: 1370 QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Query: 757 CFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEV-KEEIDP 815
K+ +++ + + + + + L K + E E+++ ++E D
Sbjct: 1430 ----RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 816 ---DEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDE 872
+EE+ +++ D+K + +E+ E E + ++ E Q Q + +F ++ +
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQEL---RSQEPERKFLEE---EQQLHRQQRQRKFLQEEQQ 1539
Query: 873 ARVQYEG 879
R Q G
Sbjct: 1540 LRRQERG 1546
Score = 34.7 bits (78), Expect = 0.60
Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 12/91 (13%)
Query: 1200 REPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLF 1259
R+ +RK L L + ++ R +E R Q+ EE++L RQ+ R + F
Sbjct: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR--QEREEQQLSRQE--RDRKF 1581
Query: 1260 RIQGQKERRNQ--------KSSLKGAEGQLQ 1282
R++ QK RR + + L+ EGQ Q
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Score = 34.3 bits (77), Expect = 0.79
Identities = 19/83 (22%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
Query: 1200 REPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLF 1259
+E ER+ A + L + + ++ ++ L +E ++K EEK +++++ + ++F
Sbjct: 181 QEREERR--AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF 238
Query: 1260 RIQGQKERRNQKSSLKGAEGQLQ 1282
+ + +KE R +++ L+ E +LQ
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQ 261
Score = 34.3 bits (77), Expect = 0.79
Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 7/91 (7%)
Query: 1181 KTQAKAGKVPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAK 1240
K + K + R+R E RK+ + ++ ++ ++Q+ L ++ R K
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKL-----ERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 1241 QKEEEEKLKRQKDLRKKLFRIQGQKERRNQK 1271
Q EEE+ ++Q++ R++ R + Q+ERR Q+
Sbjct: 310 Q--EEERREQQEERREQQERREQQEERREQQ 338
Score = 33.9 bits (76), Expect = 1.0
Identities = 23/84 (27%), Positives = 47/84 (55%), Gaps = 10/84 (11%)
Query: 1193 RRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEE---EKLK 1249
R+R V+R+ E+ L +++++ +EQ ++ R +++EEE ++L+
Sbjct: 247 RKRETVLRKEEEK-----LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
Query: 1250 RQKDLRKKL--FRIQGQKERRNQK 1271
R++ LR+K R + Q+ERR Q+
Sbjct: 302 REQQLRRKQEEERREQQEERREQQ 325
Score = 33.1 bits (74), Expect = 1.8
Identities = 45/217 (20%), Positives = 83/217 (38%), Gaps = 16/217 (7%)
Query: 407 DNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAE 466
+ + L+ EE+Q+ R R F +E++ + E + E+ L + +
Sbjct: 1671 EEEQLLQEGEEQQLR----RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Query: 467 EEENAEM-TDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESS 525
EEE T+Q + + RK+ EE + + +R EE + + E
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 526 EEEDCTAGEKGISGSKAAGEGSKAGLSPAN------CQSDRVNLEKSLLMKKAALPTFDS 579
+ + K + E + L P + +++ LE+ ++ L
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE----QEQRLRQERD 1842
Query: 580 GHCTAEEVFASEDES-EESSSLSAEEEDSENEEAIRK 615
AEE FA++++S E L EEE +E RK
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Score = 32.7 bits (73), Expect = 2.3
Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 1198 VIREPHERKILALLDALSTVHSQKMKKA------KEQRHLHNKEHFRAKQKEEEEKLKRQ 1251
V R+ ERK L L +K ++ +E++ LH +E R K EEE++L+RQ
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR-KFLEEEQQLRRQ 1497
Query: 1252 KDLRKKLFRIQGQKERRNQKSSLKGAEGQLQ 1282
+ R + FR ++E R+Q+ K E + Q
Sbjct: 1498 E--RDRKFR---EQELRSQEPERKFLEEEQQ 1523
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 10/72 (13%)
Query: 1200 REPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLF 1259
R+ ERK L Q++++ + +R +E R Q+ E+E+L+RQ+ RK L
Sbjct: 1702 RQERERKFLQ--------EEQQLRRQELERKFREEEQLR--QETEQEQLRRQERYRKILE 1751
Query: 1260 RIQGQKERRNQK 1271
Q + ER Q+
Sbjct: 1752 EEQLRPEREEQQ 1763
Score = 32.0 bits (71), Expect = 3.9
Identities = 28/135 (20%), Positives = 68/135 (50%), Gaps = 21/135 (15%)
Query: 1142 RLKANKDSLYKPILRQKKHFNSLHIPKALQKALPFKNKPKTQAKAGKVPKDRRRPAVIR- 1200
RLK ++ +L++++ + + ++ L + K + + ++ ++ RR ++
Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK---REEVERLEQEERREQRLKR 622
Query: 1201 -EPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKD---LRK 1256
EP E + Q++ K++EQ ++ R +Q+ E++LKR+++ L +
Sbjct: 623 EEPEEER------------RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 1257 KLFRIQGQKERRNQK 1271
+L R + ++ERR Q+
Sbjct: 671 RLKR-EHEEERREQE 684
Score = 31.6 bits (70), Expect = 5.1
Identities = 19/91 (20%), Positives = 45/91 (49%)
Query: 1181 KTQAKAGKVPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAK 1240
+ Q + + ++RR + RE ER+ L ++ + +++ ++ R +
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 1241 QKEEEEKLKRQKDLRKKLFRIQGQKERRNQK 1271
Q E++L+R++ LR++ + Q+ RR Q+
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Score = 31.2 bits (69), Expect = 6.7
Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 1181 KTQAKAGKVPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAK 1240
K + + + ++RR + RE ER+ L Q+ ++++Q +E
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 1241 QKEEEEKLKRQKDLRKKLFRIQGQKERRNQ 1270
K EEEK Q+ ++L R Q+ERR+Q
Sbjct: 550 LKREEEKRLEQERREQRLKR--EQEERRDQ 577
Score = 31.2 bits (69), Expect = 6.7
Identities = 36/153 (23%), Positives = 71/153 (46%), Gaps = 9/153 (5%)
Query: 1129 MRTTGQLRLAHGVR-LKANKDSLYKPI--LRQKKHFNSLHIPKALQKALPFKNKPKTQAK 1185
M QLR G + L+ +D ++ L Q++ LH + +K L + + + Q +
Sbjct: 1598 MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER 1657
Query: 1186 AGKVPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEE 1245
++ DR R RE E ++L + ++ +K +E+ ++ K +EE
Sbjct: 1658 EQQLRHDRDRK--FRE--EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 1246 EKLKRQKDLRKKLFRIQGQKERRNQKSSLKGAE 1278
++L+RQ+ RK FR + Q + ++ L+ E
Sbjct: 1714 QQLRRQELERK--FREEEQLRQETEQEQLRRQE 1744
Score = 30.8 bits (68), Expect = 8.7
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 1181 KTQAKAGKVPKDRRRPAVIREPHE--RKILALLDALSTVHSQKMKKAKEQRHLHNKEHFR 1238
K + + + ++RR+ + R+ E R+ L+ Q+ ++ + +R + R
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 1239 AKQKEEEEKLKRQKDLRKKLFRIQGQKERRNQ 1270
K++EEEE+L Q+ LR + + Q+ERR Q
Sbjct: 519 LKRQEEEERL--QQRLRSEQQLRREQEERREQ 548
Score = 30.8 bits (68), Expect = 8.7
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 14/109 (12%)
Query: 1177 KNKPKTQAKAGKVPKDRRRPAVIREPHERKILALLDALSTVHSQKMKKAKEQRHLHNKE- 1235
K + K + G+ P+ RRR ++ E + L Q +++ +E+R E
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREE------EELQQEEEQLLREEREKRRRQEWER 1018
Query: 1236 HFRAK---QKEEEEKLKRQKDLRKKLFRIQGQKERRNQKSSLKGAEGQL 1281
+R K Q+EEE+ L+ +++ R R+Q ++ + ++ L+ E QL
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKR----RLQERERQYREEEELQQEEEQL 1063
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 56.2 bits (134), Expect = 2e-07
Identities = 58/249 (23%), Positives = 102/249 (40%), Gaps = 8/249 (3%)
Query: 399 KPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLEN 458
+P ++D+ G KE + + +A +E+E D DD +D + SE+D E+
Sbjct: 1022 RPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDD-ED 1080
Query: 459 GSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGE- 517
+ E +E++E ++ +++ K E SE F S + SS +E E
Sbjct: 1081 TALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESS--EFESSSESSPSSSEDEEEV 1138
Query: 518 -AEEADESSEEEDCTAGEKGISGSKAAGE--GSKAGLSPANCQSDRVNLEKSLLMKKAAL 574
A E +E EEE+ A E S E G +A L+P D + +E+ + ++ A+
Sbjct: 1139 VAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAV 1198
Query: 575 PTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPS-QVSSGQKLGPQN 633
+ E E S EE E A+ P+ +V + L P+
Sbjct: 1199 APEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER 1258
Query: 634 FIDETSDIE 642
+ ++E
Sbjct: 1259 APEHDLEVE 1267
Score = 47.0 bits (110), Expect = 1e-04
Identities = 59/229 (25%), Positives = 91/229 (39%), Gaps = 54/229 (23%)
Query: 462 DEEAEEEENAEMTDQYMAVK-------GIKRRK---LELEEDSEMDLPAFADSDDDLERS 511
DEE+E E + +M D + G++RR LEL+ E D +S + + S
Sbjct: 991 DEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEK---ESLSEEQES 1047
Query: 512 SAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKK 571
+ EE EAEE +E +++D + ++ ++ + LS A+ EK
Sbjct: 1048 TEEEEEAEEEEEEEDDDDDDSDDR----DESENDDEDTALSEAS--------EK------ 1089
Query: 572 AALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGP 631
D G EE + E++S S E SE E S + P
Sbjct: 1090 ------DEGDSDEEETVSIVTSKAEATSSSESSESSEFE--------------SSSESSP 1129
Query: 632 QNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFL 680
+ DE E + +EEE+ +EE E S A ED + EA L
Sbjct: 1130 SSSEDEE---EVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAAL 1175
Score = 33.1 bits (74), Expect = 1.8
Identities = 50/273 (18%), Positives = 101/273 (36%), Gaps = 52/273 (19%)
Query: 574 LPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEE---------------------A 612
LP+F + +S D+ S S +EED E+E
Sbjct: 959 LPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVG 1018
Query: 613 IRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLS 672
+R++ ++P ++ SG + + + E + +E E+ +EE +D + S E+
Sbjct: 1019 VRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDD 1078
Query: 673 RKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSL 732
A ++E +E+++ D+ EE + E ++S
Sbjct: 1079 EDTA--------------------LSEASEKDEGDSDEE--ETVSIVTSKAEATSSSESS 1116
Query: 733 DCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETG--D 790
+ S F + E + V + E++++ +++AE+ ED E +
Sbjct: 1117 ESSEFESSSESSPSSSEDEEEV----VAREEEEEEEEEEMVAEESMASAGPEDFEQDGEE 1172
Query: 791 VHKGKSGPNTQNEDIEKEV---KEEIDPDEEES 820
P + +E+EV E + P+E S
Sbjct: 1173 AALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 55.5 bits (132), Expect = 3e-07
Identities = 87/395 (22%), Positives = 141/395 (35%), Gaps = 83/395 (21%)
Query: 461 SDEEAEEEENAEMTDQYMAVKG-IKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAE 519
S+ + + NA+ T MA + I +K E ED + E ++E E
Sbjct: 403 SEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDG-----------GEFEEGASENNAKE 451
Query: 520 EADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDS 579
+ E EE C E K EGS
Sbjct: 452 SSPEKEAEEGCPEKESEEGCPKRGFEGS-------------------------------- 479
Query: 580 GHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETS 639
S+ ESEE + + EEDS +E+ +K L + + K + E+
Sbjct: 480 ---------CSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESE 530
Query: 640 DIENLLKEEED---YKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGT 696
+ KE E+ KE + D E + + E L ++ + L + +
Sbjct: 531 EEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDK 590
Query: 697 VTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRD 756
E+N+ E+ + E+ G +++ E + DS + EE ++
Sbjct: 591 ELEENDSENSE-FEDDGSEKVLDEEGSEREFDEDS-------------DEKEEEEDTYEK 636
Query: 757 CFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPD 816
F DD+ K EDEE Y D + LE D K + G + E + KE+ D D
Sbjct: 637 VF------DDESDEK---EDEE-YADEKGLEAAD-KKAEEGDADEKLFEESDDKEDEDAD 685
Query: 817 --EEESAKKKHLDKKRKLKEMFDAEYDEGESTYFD 849
E E A +K + +++FD E D E + D
Sbjct: 686 GKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDD 720
Score = 51.6 bits (122), Expect = 5e-06
Identities = 63/277 (22%), Positives = 114/277 (41%), Gaps = 24/277 (8%)
Query: 404 EDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDE 463
E ID + ++ + + K +++ ++E +E G E S +
Sbjct: 424 EPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQK 483
Query: 464 EAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEE----GEAE 519
E+EE +++ K + +K L+ D E + A +S+DDL + S EE E+E
Sbjct: 484 ESEEGNPVRGSEEDSPKK--ESKKKTLKNDCEENGLA-KESEDDLNKESEEEVGPTKESE 540
Query: 520 EADESSEEEDCTAGEKGISGSKAAGE--GSKAGLSPANCQSDRVN--LEKSLLMKKAALP 575
E D E ++ + ++ GS+ E G + L + + L+K L +
Sbjct: 541 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS 600
Query: 576 TF-DSGHCTAEEVFASEDESEESSSLSAEEEDS-------ENEEAIRKKLSKPSQVSSGQ 627
F D G + SE E +E S EEED+ E++E ++ + + +
Sbjct: 601 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD 660
Query: 628 KLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGA 664
K + D E L +E +D ++E+ D KE A
Sbjct: 661 KKAEEGDAD-----EKLFEESDDKEDEDADGKEVEDA 692
Score = 51.6 bits (122), Expect = 5e-06
Identities = 47/178 (26%), Positives = 81/178 (45%), Gaps = 18/178 (10%)
Query: 363 QDEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSE-DIDNQGL-------MMP 414
++EVGPT E + S D S + + G E D+D +G ++
Sbjct: 530 EEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLD 589
Query: 415 KEEKQMDLNTGRMR---RKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENA 471
KE ++ D + + +E + D++ D++ E+D E D+E++E+E+
Sbjct: 590 KELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEK-VFDDESDEKEDE 648
Query: 472 EMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEED 529
E D+ KG++ + EE + D F +SDD E A+ E E+ADE E+D
Sbjct: 649 EYADE----KGLEAADKKAEE-GDADEKLFEESDDK-EDEDADGKEVEDADEKLFEDD 700
Score = 50.1 bits (118), Expect = 1e-05
Identities = 61/262 (23%), Positives = 113/262 (43%), Gaps = 34/262 (12%)
Query: 414 PKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEM 473
P + D ++K + D +E+G + + EDD E + E +E+EE+++ +
Sbjct: 490 PVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESE--EEVGPTKESEEDDSEKE 547
Query: 474 TDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEA-----DESSEEE 528
+D+ + K + E+ SE + ++ LE+ EEG +E D+ EE
Sbjct: 548 SDEDCSEK-------QSEDGSEREF-----EENGLEKDLDEEGSEKELHENVLDKELEEN 595
Query: 529 DCTAGEKGISGSKAA--GEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEE 586
D E GS+ EGS+ + + + + + D + +
Sbjct: 596 DSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKG 655
Query: 587 VFASEDESEESSS---LSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIEN 643
+ A++ ++EE + L E +D E+E+A K++ + +KL F D+ S+ E
Sbjct: 656 LEAADKKAEEGDADEKLFEESDDKEDEDADGKEVE-----DADEKL----FEDDDSN-EK 705
Query: 644 LLKEEEDYKEENNDSKETSGAL 665
L EEED E+ D + G L
Sbjct: 706 LFDEEEDSSEKLFDDSDERGTL 727
Score = 39.3 bits (90), Expect = 0.024
Identities = 62/297 (20%), Positives = 111/297 (37%), Gaps = 48/297 (16%)
Query: 595 EESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEE 654
E + L + S +E A + S+ S K+ Q + E + +++ + E+
Sbjct: 377 EANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTED 436
Query: 655 NNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGG 714
+ +E + KE K AE ++++ K + E E+ + +
Sbjct: 437 GGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGS-- 494
Query: 715 LFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLA 774
+ P +E K K DC + + DL +
Sbjct: 495 --EEDSPKKESKKKTLKNDCEENGLAKESEDDLNK------------------------- 527
Query: 775 EDEELYGDFEDLETGDVHK--GKSGPNTQNED-IEKEVKE---EIDPDEEESAKKKH--- 825
E EE G ++ E D K + Q+ED E+E +E E D DEE S K+ H
Sbjct: 528 ESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENV 587
Query: 826 LDKKRKLKEMFDAEY----------DEGESTYFDDLKGEMQKQAQLNRAEFEDQDDE 872
LDK+ + + ++E+ +EG FD+ E +++ F+D+ DE
Sbjct: 588 LDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDE 644
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 55.5 bits (132), Expect = 3e-07
Identities = 87/395 (22%), Positives = 141/395 (35%), Gaps = 83/395 (21%)
Query: 461 SDEEAEEEENAEMTDQYMAVKG-IKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAE 519
S+ + + NA+ T MA + I +K E ED + E ++E E
Sbjct: 403 SEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDG-----------GEFEEGASENNAKE 451
Query: 520 EADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDS 579
+ E EE C E K EGS
Sbjct: 452 SSPEKEAEEGCPEKESEEGCPKRGFEGS-------------------------------- 479
Query: 580 GHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETS 639
S+ ESEE + + EEDS +E+ +K L + + K + E+
Sbjct: 480 ---------CSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESE 530
Query: 640 DIENLLKEEED---YKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGT 696
+ KE E+ KE + D E + + E L ++ + L + +
Sbjct: 531 EEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDK 590
Query: 697 VTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRD 756
E+N+ E+ + E+ G +++ E + DS + EE ++
Sbjct: 591 ELEENDSENSE-FEDDGSEKVLDEEGSEREFDEDS-------------DEKEEEEDTYEK 636
Query: 757 CFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPD 816
F DD+ K EDEE Y D + LE D K + G + E + KE+ D D
Sbjct: 637 VF------DDESDEK---EDEE-YADEKGLEAAD-KKAEEGDADEKLFEESDDKEDEDAD 685
Query: 817 --EEESAKKKHLDKKRKLKEMFDAEYDEGESTYFD 849
E E A +K + +++FD E D E + D
Sbjct: 686 GKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDD 720
Score = 51.6 bits (122), Expect = 5e-06
Identities = 63/277 (22%), Positives = 114/277 (41%), Gaps = 24/277 (8%)
Query: 404 EDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDE 463
E ID + ++ + + K +++ ++E +E G E S +
Sbjct: 424 EPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQK 483
Query: 464 EAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEE----GEAE 519
E+EE +++ K + +K L+ D E + A +S+DDL + S EE E+E
Sbjct: 484 ESEEGNPVRGSEEDSPKK--ESKKKTLKNDCEENGLA-KESEDDLNKESEEEVGPTKESE 540
Query: 520 EADESSEEEDCTAGEKGISGSKAAGE--GSKAGLSPANCQSDRVN--LEKSLLMKKAALP 575
E D E ++ + ++ GS+ E G + L + + L+K L +
Sbjct: 541 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS 600
Query: 576 TF-DSGHCTAEEVFASEDESEESSSLSAEEEDS-------ENEEAIRKKLSKPSQVSSGQ 627
F D G + SE E +E S EEED+ E++E ++ + + +
Sbjct: 601 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD 660
Query: 628 KLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGA 664
K + D E L +E +D ++E+ D KE A
Sbjct: 661 KKAEEGDAD-----EKLFEESDDKEDEDADGKEVEDA 692
Score = 51.6 bits (122), Expect = 5e-06
Identities = 47/178 (26%), Positives = 81/178 (45%), Gaps = 18/178 (10%)
Query: 363 QDEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSE-DIDNQGL-------MMP 414
++EVGPT E + S D S + + G E D+D +G ++
Sbjct: 530 EEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLD 589
Query: 415 KEEKQMDLNTGRMR---RKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENA 471
KE ++ D + + +E + D++ D++ E+D E D+E++E+E+
Sbjct: 590 KELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEK-VFDDESDEKEDE 648
Query: 472 EMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEED 529
E D+ KG++ + EE + D F +SDD E A+ E E+ADE E+D
Sbjct: 649 EYADE----KGLEAADKKAEE-GDADEKLFEESDDK-EDEDADGKEVEDADEKLFEDD 700
Score = 50.1 bits (118), Expect = 1e-05
Identities = 61/262 (23%), Positives = 113/262 (43%), Gaps = 34/262 (12%)
Query: 414 PKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEM 473
P + D ++K + D +E+G + + EDD E + E +E+EE+++ +
Sbjct: 490 PVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESE--EEVGPTKESEEDDSEKE 547
Query: 474 TDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEA-----DESSEEE 528
+D+ + K + E+ SE + ++ LE+ EEG +E D+ EE
Sbjct: 548 SDEDCSEK-------QSEDGSEREF-----EENGLEKDLDEEGSEKELHENVLDKELEEN 595
Query: 529 DCTAGEKGISGSKAA--GEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEE 586
D E GS+ EGS+ + + + + + D + +
Sbjct: 596 DSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKG 655
Query: 587 VFASEDESEESSS---LSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIEN 643
+ A++ ++EE + L E +D E+E+A K++ + +KL F D+ S+ E
Sbjct: 656 LEAADKKAEEGDADEKLFEESDDKEDEDADGKEVE-----DADEKL----FEDDDSN-EK 705
Query: 644 LLKEEEDYKEENNDSKETSGAL 665
L EEED E+ D + G L
Sbjct: 706 LFDEEEDSSEKLFDDSDERGTL 727
Score = 39.3 bits (90), Expect = 0.024
Identities = 62/297 (20%), Positives = 111/297 (37%), Gaps = 48/297 (16%)
Query: 595 EESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEE 654
E + L + S +E A + S+ S K+ Q + E + +++ + E+
Sbjct: 377 EANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTED 436
Query: 655 NNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGG 714
+ +E + KE K AE ++++ K + E E+ + +
Sbjct: 437 GGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGS-- 494
Query: 715 LFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLA 774
+ P +E K K DC + + DL +
Sbjct: 495 --EEDSPKKESKKKTLKNDCEENGLAKESEDDLNK------------------------- 527
Query: 775 EDEELYGDFEDLETGDVHK--GKSGPNTQNED-IEKEVKE---EIDPDEEESAKKKH--- 825
E EE G ++ E D K + Q+ED E+E +E E D DEE S K+ H
Sbjct: 528 ESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENV 587
Query: 826 LDKKRKLKEMFDAEY----------DEGESTYFDDLKGEMQKQAQLNRAEFEDQDDE 872
LDK+ + + ++E+ +EG FD+ E +++ F+D+ DE
Sbjct: 588 LDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDE 644
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 55.5 bits (132), Expect = 3e-07
Identities = 63/238 (26%), Positives = 97/238 (40%), Gaps = 24/238 (10%)
Query: 435 DEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDS 494
DED+ D DDE+DD+ EDD S+EEA E A+ V +K + + +ED
Sbjct: 186 DEDDEDDEDDEDDDDDEEDD------SEEEAMETTPAKGKKAAKVVP-VKAKNVAEDEDE 238
Query: 495 EMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAG----EKGISGSKAAGEGSKAG 550
E D D DDD + ++ + EE +E EEE +K ++ KAA E K
Sbjct: 239 EED-DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297
Query: 551 LSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEE----D 606
+ + NL L + P +G +VFA D + + + D
Sbjct: 298 VEGTE-PTTAFNLFVGNLNFNKSAPELKTG---ISDVFAKNDLAVVDVRIGMTRKFGYVD 353
Query: 607 SENEEAIRKKLSKPSQVSSGQKLGPQNFIDETS----DIENLLKEEEDYKEENNDSKE 660
E+ E + K L G ++ + + S D LL + YK ++ KE
Sbjct: 354 FESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKE 411
Score = 51.6 bits (122), Expect = 5e-06
Identities = 50/199 (25%), Positives = 79/199 (39%), Gaps = 43/199 (21%)
Query: 434 GDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEED 493
G + DSD+EEDD+ ED+ D+E E+E+ E+ + A+K +ED
Sbjct: 137 GKNAKKEDSDEEEDDDSEEDE------EDDEDEDEDEDEI--EPAAMKAAAAAPASEDED 188
Query: 494 SEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSP 553
E D +DD E+ + +E D+S EE T KG +K +K
Sbjct: 189 DE-------DDEDD------EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAK----- 230
Query: 554 ANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAI 613
N D E E+ ED+ ++ EEE+ E EE +
Sbjct: 231 -NVAEDEDEEEDD----------------EDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273
Query: 614 RKKLSKPSQVSSGQKLGPQ 632
++ K + + QK P+
Sbjct: 274 KEAPGKRKKEMAKQKAAPE 292
Score = 45.8 bits (107), Expect = 3e-04
Identities = 59/269 (21%), Positives = 106/269 (39%), Gaps = 48/269 (17%)
Query: 443 DDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFA 502
+D ED+EMSED+ D EE + + A K+ + + + PA
Sbjct: 26 EDSEDEEMSEDE-----EDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPA-- 78
Query: 503 DSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVN 562
++++ G+ A T +K ++ +KA K G +P
Sbjct: 79 ------KKAAVTPGKKAAA---------TPAKKTVTPAKAVTTPGKKGATPGKA------ 117
Query: 563 LEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQ 622
L + K AA+P G + + + EE +EED E+E+ ++ +
Sbjct: 118 LVATPGKKGAAIPA--KGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAM 175
Query: 623 VSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQ 682
++ ++ DE + +E+D +E +DS+E A++ +KAA+
Sbjct: 176 KAAAAAPASEDEDDEDDE-----DDEDDDDDEEDDSEEE--AMETTPAKGKKAAKV---- 224
Query: 683 QQAAPNLRKLIYGTVTEDNEEEDDDTLEE 711
P K V ED +EE+DD E+
Sbjct: 225 ---VPVKAK----NVAEDEDEEEDDEDED 246
Score = 38.9 bits (89), Expect = 0.032
Identities = 68/319 (21%), Positives = 136/319 (42%), Gaps = 57/319 (17%)
Query: 515 EGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAAL 574
E ++E+ + S +EED ++GE+ + K +G KA + A +V + + KK A+
Sbjct: 25 EEDSEDEEMSEDEEDDSSGEEVVIPQK---KGKKAAATSAK----KVVVSPT---KKVAV 74
Query: 575 PTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQ--VSSGQKLGPQ 632
T A++ + + ++ ++ KK + P + V++ K G
Sbjct: 75 AT------PAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAA 128
Query: 633 NFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKL 692
+ +N KE+ D +EE++DS+E + +++ + A ++ AAP
Sbjct: 129 IPAKGAKNGKNAKKEDSD-EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP----- 182
Query: 693 IYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMN 752
+ED ++EDD+ E+ + D E + ++++ + P +
Sbjct: 183 ----ASEDEDDEDDEDDED-------DDDDEEDDSEEEAMETT------PAKGKKAAKVV 225
Query: 753 SIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEE 812
++ AK +AEDE+ D ED + D + + +D E+E +EE
Sbjct: 226 PVK--------------AKNVAEDEDEEEDDEDEDDDDDEDDED--DDDEDDEEEEEEEE 269
Query: 813 IDPDEEESAKKKHLDKKRK 831
+P +E K+K K+K
Sbjct: 270 EEPVKEAPGKRKKEMAKQK 288
Score = 36.2 bits (82), Expect = 0.21
Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 6/109 (5%)
Query: 764 EDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEESAKK 823
E+D D+ + +DE+ D +++E + + P +++ED E + +E D D+EE
Sbjct: 148 EEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEED--- 204
Query: 824 KHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDE 872
D + + E A+ + K + + + E ED DD+
Sbjct: 205 ---DSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDD 250
Score = 34.7 bits (78), Expect = 0.60
Identities = 44/215 (20%), Positives = 89/215 (41%), Gaps = 34/215 (15%)
Query: 416 EEKQMDLNT--GRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEM 473
EE+ M+ G+ K + + +DEE+D+ EDD + D++ E++E E
Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266
Query: 474 TDQYMAVKGIK-RRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTA 532
++ VK +RK E+ ++ +A E + ++ + +
Sbjct: 267 EEEEEPVKEAPGKRKKEM-----------------AKQKAAPEAKKQKVEGTEPTTAFNL 309
Query: 533 GEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSL-LMKKAALPTFDSG-------HCTA 584
++ +K+A E K G+S ++D ++ + + +K F+S T
Sbjct: 310 FVGNLNFNKSAPE-LKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTG 368
Query: 585 EEVFASEDESEESSSLSAEEEDSENEEAIRKKLSK 619
+VF +E + E+ +DS+ E R L+K
Sbjct: 369 LKVFGNEIKLEKPKG-----KDSKKERDARTLLAK 398
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 54.3 bits (129), Expect = 7e-07
Identities = 114/541 (21%), Positives = 211/541 (39%), Gaps = 60/541 (11%)
Query: 371 ELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRK 430
+L L H +D+ S + + L D Q L++ KEE++ L
Sbjct: 702 DLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELT 761
Query: 431 AIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEE----------EENAEMTDQ---Y 477
A+ G E S D+E D++ E E + E EE N DQ
Sbjct: 762 ALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTE 821
Query: 478 MAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGI 537
M VK ++ +L+ SE A +E +E +A+E + E E E +
Sbjct: 822 MRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALV 881
Query: 538 SGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASE---DES 594
K E A R LE L + L T E+ SE +ES
Sbjct: 882 HARKEEKEAVSA----------RRALENELEAAQGNL-----SQTTQEQKQLSEKLKEES 926
Query: 595 EESSSLSAEEEDSENE--------EAIRKKLSKPSQVSSGQKLGPQNFIDE--TSDIENL 644
E+ L + + ENE E ++K+++ + S L QN +DE + L
Sbjct: 927 EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRREL 986
Query: 645 LKEEEDYKEENNDS-KETSGALKWKE----------DLSRKAAEAFLRQQQAAPNLRKLI 693
+ + KE+ ++ K A+K ++ D R EA ++Q L+ L
Sbjct: 987 AEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLE 1046
Query: 694 YGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNS 753
Y + + ++D L + +V+Q + E + + ++ D + + +E++ N
Sbjct: 1047 YELEAKSHLKDDRSRLVKQME-DKVSQLEMELEEERNNSDLLSERISRSRE-QMEQLRNE 1104
Query: 754 IRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEI 813
+ + + + D + ++++L LE G K G Q E E+++ +
Sbjct: 1105 LLQ-ERAARQDLECDKISLERQNKDLKSRIIHLE-GSYRSSKEGLVVQMEARIAELEDRL 1162
Query: 814 DPDEEESAKKKHLDKK--RKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDD 871
+ +E + A + +++ RK+KE+ DE S D K ++ + + + + E+ ++
Sbjct: 1163 ESEERDRANLQLSNRRLERKVKELVMQVDDEHLS--LTDQKDQLSLRLKAMKRQVEEAEE 1220
Query: 872 E 872
E
Sbjct: 1221 E 1221
Score = 41.6 bits (96), Expect = 0.005
Identities = 74/390 (18%), Positives = 158/390 (40%), Gaps = 59/390 (15%)
Query: 515 EGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAAL 574
+G+ E + S E A G K E K + Q+ KK ++
Sbjct: 467 DGKVLETEGSQESTVIRAPSLGAQSKKE--EEVKTATATLMLQNRATATSPDSGAKKISV 524
Query: 575 PTFDSG---HCTAEEVFASEDESEESSSLSAE--------EEDSENEEAIRKKLSKPSQV 623
TF S T + + ++ +++++ +A+ E ++N++A ++K++ +
Sbjct: 525 KTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEK 584
Query: 624 -------SSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSK-----ETSGALKWKEDL 671
++G G + TS++++LL+++ E + + E KE+
Sbjct: 585 IQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEER 644
Query: 672 SRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADS 731
R A L + ++ N + T+ + EE + + + L LF+V +RE +H+ +
Sbjct: 645 ERMRAN--LEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKM-ERE-QHQTEI 700
Query: 732 LDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDV 791
D L++ ++ + D + K +D++ ++ E + D +DL
Sbjct: 701 RD-------------LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIA-- 745
Query: 792 HKGKSGPNTQNEDIEKEVKEEIDP-----DEEESAKKKHLDKKRKLKEMFDAEYDEGEST 846
+ ED+ ++ + E+ EE S+ + +DK LKE +DAE +
Sbjct: 746 -------KEEQEDLLRKRERELTALKGALKEEVSSHDQEMDK---LKEQYDAELQALRES 795
Query: 847 YFDDLKGEMQKQAQLNRAEFEDQDDEARVQ 876
+ K ++ N +E + E RV+
Sbjct: 796 VEEATKNVEVLASRSNTSEQDQAGTEMRVK 825
Score = 38.9 bits (89), Expect = 0.032
Identities = 97/517 (18%), Positives = 207/517 (40%), Gaps = 65/517 (12%)
Query: 398 SKPLGSEDIDNQGLMMPKEEK-------QMDLNTGRMRRKAIFGDEDESGDSDDEEDDEM 450
S+ GS +NQ E K ++ + ++R+ E ++ + EE + M
Sbjct: 590 SRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQL--EVKNQQNIKEERERM 647
Query: 451 SEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLER 510
+ LE S + EEN+ + + +G R+ LE +M+ DL+
Sbjct: 648 RAN--LEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQD 705
Query: 511 SSAEEGEAEEADESSEEEDCTAGEKG--ISGSKAAGEGSKAGLSPANCQSDRV-NLEKSL 567
+E +E D + ED EKG I A + + L Q D + E+ L
Sbjct: 706 QLSE--MHDELDSAKRSED---REKGALIEELLQAKQDLQDLLIAKEEQEDLLRKREREL 760
Query: 568 LMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQ 627
K AL S H + + ++E + + EE ++N E + + + Q +G
Sbjct: 761 TALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGT 820
Query: 628 KLGPQNFIDETSDIE-----------NLLKEEEDYKEENNDSKET----SGALKWKEDL- 671
++ + +E ++ L ++ ED K + +KET G ++ E+
Sbjct: 821 EMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEAL 880
Query: 672 --SRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEE---------EDDDTLEELGGLFRVNQ 720
+RK + + ++A N + G +++ +E E+ + E+L L N+
Sbjct: 881 VHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRL--KNE 938
Query: 721 PDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELY 780
+ E H +++ ++ +++ + R + + + D+ K E E+
Sbjct: 939 MENERWHLGKTIE--------KLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQ 990
Query: 781 GDFEDLETGDVHKGKSGPNTQNED---IEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFD 837
++ +T + K + ++ +E+E+++ +E K++ L++ K D
Sbjct: 991 RQLKE-KTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLK-----D 1044
Query: 838 AEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEAR 874
EY+ ++ D + + KQ + ++ E + +E R
Sbjct: 1045 LEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEER 1081
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 53.9 bits (128), Expect = 1e-06
Identities = 95/452 (21%), Positives = 166/452 (36%), Gaps = 96/452 (21%)
Query: 435 DEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDS 494
D+DE GDS + E+ DD + G+S + + ++E +D R + D
Sbjct: 46 DQDERGDSGQPSNKELFGDDSEDEGAS-HHSGSDNHSERSD--------NRSEASERSDH 96
Query: 495 EMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPA 554
E + P+ D E + +E E +D S + EK S + G K+
Sbjct: 97 EDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSD---- 152
Query: 555 NCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIR 614
QSD ++ S E S+++ ++S + +++++EE +
Sbjct: 153 --QSDDEKIQNS---------------DDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQ 195
Query: 615 KKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDLSRK 674
+ Q+S +K SD E + + D +++N+D +E L +E +
Sbjct: 196 LSDDERQQLSEEEK--------ANSDDERPVASDNDDEKQNSDDEE-QPQLSDEEKMQNS 246
Query: 675 AAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDC 734
E R Q + R D+EEE D E G +DS D
Sbjct: 247 DDE---RPQASDEEHRH-------SDDEEEQDHKSESARG--------------SDSED- 281
Query: 735 SRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKD--AAKVLAEDEELYGDFEDLETGDVH 792
EV+ R + E D D K + +L+G +D+ +G
Sbjct: 282 --------------EVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGS-- 325
Query: 793 KGKSGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLK 852
G+ P T + +++ + D EEE + ++ E+ D G YF L
Sbjct: 326 DGEDKPPTPGQPVDENGLPQ-DQQEEEPIPETRIE-----VEIPKVNTDLGNDLYFVKLP 379
Query: 853 GEMQKQ-----AQLNRAEFEDQ---DDEARVQ 876
+ + Q EFED+ D+E R +
Sbjct: 380 NFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTR 411
Score = 41.6 bits (96), Expect = 0.005
Identities = 31/124 (25%), Positives = 61/124 (49%), Gaps = 20/124 (16%)
Query: 407 DNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDE--E 464
D++ + +EEK + R ++DE +SDDEE ++S+++ ++N S DE +
Sbjct: 198 DDERQQLSEEEKANSDD----ERPVASDNDDEKQNSDDEEQPQLSDEEKMQN-SDDERPQ 252
Query: 465 AEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADES 524
A +EE+ D E E+D + + +DS+D++ R + A +++
Sbjct: 253 ASDEEHRHSDD-------------EEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEAD 299
Query: 525 SEEE 528
S+ E
Sbjct: 300 SDTE 303
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 53.5 bits (127), Expect = 1e-06
Identities = 75/307 (24%), Positives = 129/307 (42%), Gaps = 40/307 (13%)
Query: 436 EDESGDSDDEEDDEMSEDDGLENGSSD-------EEAEEEE---NAEMTDQYMAVKGIKR 485
E+E G ++EE+DE ++ D E G S+ EE E+EE AE + K K+
Sbjct: 528 EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKK 587
Query: 486 ---------RKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKG 536
K EL D++++ P A S + +S EE +S EE G+
Sbjct: 588 VEEKSEEVATKEELVADAKVEKPEKAKS--PVPKSPVEEKGKSPVPKSPVEE---KGKSP 642
Query: 537 ISGSKAAGEG-SKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAE---EVFASED 592
+ S +G S SP + + + KS + +KA P S A+ EV E
Sbjct: 643 VPKSPVEEKGKSPVPKSPVE-EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQ 701
Query: 593 ESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYK 652
+ EE E +++ EE + KK KP V +K + +++ + K + +
Sbjct: 702 KEEEEK----EVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHL 757
Query: 653 EENNDSKETSGALKWKEDLSRKAAEAFLRQQ---QAAPNLRK--LIYGTVTEDNEEEDDD 707
E+ ++KE L+ +++ + E ++ + A RK + E EE + +
Sbjct: 758 EK--ETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQE 815
Query: 708 TLEELGG 714
T E+ G
Sbjct: 816 TKEKGSG 822
Score = 41.6 bits (96), Expect = 0.005
Identities = 92/496 (18%), Positives = 204/496 (41%), Gaps = 71/496 (14%)
Query: 413 MPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAE 472
+ ++ K+++ +R+K + GD+ D+E E+ LE + ++ + ++
Sbjct: 122 LEQQNKEIEAEIQALRQKQ--ASHAQLGDAYDQEIRELRAT--LEMVNHEKAQVQLDSDH 177
Query: 473 MTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTA 532
+ + +K + L +D+E + A D+E +S + E ++ +S ++E
Sbjct: 178 LEEDIHRLKERFEEEARLRDDTEAAIRALRK---DIEEASLVKVELDKKVQSLQDE---- 230
Query: 533 GEKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASED 592
++ ++ E A L A Q+ + +E+ +K + TA + S+
Sbjct: 231 ----VAFLRSNHEEEVADLL-AQIQASHITVERKDYLK--------TDISTALKEIRSQL 277
Query: 593 ESEESSSLSAEEE------------DSENEEAIR---KKLSKPSQVSSGQKLGPQNFIDE 637
ES ++ EE +N+EAIR +++++ + + + ++
Sbjct: 278 ESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGT 337
Query: 638 TSDIENLLKE-EEDYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLI--- 693
+E L + EE + + + ++T L+ + ++ LR+ Q N++ +
Sbjct: 338 KESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIE 397
Query: 694 ---YGTVTEDNEEEDDDTLEELGGLFRVNQPD-------RECKHKADSLDCSRFLVEA-- 741
Y + E E + G ++P ++ K +A L VE
Sbjct: 398 IAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEII 457
Query: 742 ------PHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGK 795
++EE + +I + E+ K+AA+ ++EE + E++
Sbjct: 458 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAE--EKEEEPEAEEEEVAAKKSPVKA 515
Query: 796 SGPNTQNEDIEKEVKE--EIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKG 853
+ P + E+ EKE +E E + +E+E AK ++ KE +E +EGE +G
Sbjct: 516 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE-GSSEKEEGEQE-----EG 569
Query: 854 EMQKQAQLNRAEFEDQ 869
E + +A+ AE +++
Sbjct: 570 ETEAEAEGEEAEAKEE 585
Score = 36.2 bits (82), Expect = 0.21
Identities = 67/316 (21%), Positives = 119/316 (37%), Gaps = 30/316 (9%)
Query: 583 TAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIE 642
T E + ++E +E++ EE ++E EE KK P + ++ + + +E E
Sbjct: 477 TEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK--SPVKATAPEVKEEEGEKEEEEGQE 534
Query: 643 NLLKEEE----DYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVT 698
+E+E D EE KE S K + + EA ++A K +
Sbjct: 535 EEEEEDEGAKSDQAEEGGSEKEGSSE-KEEGEQEEGETEAEAEGEEAEAKEEKKV----- 588
Query: 699 EDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCF 758
+ + E+ T EEL +V +P++ S + P E+ + +
Sbjct: 589 -EEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 647
Query: 759 VT--GKWEDDKDAAKVLAEDEELYGDFEDLETGDV---------HKGKSGPNTQNEDIEK 807
V GK K + + E+ V K + G Q E+ EK
Sbjct: 648 VEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK 707
Query: 808 EVKEEIDPDEEESAKK----KHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNR 863
EVKE P EE+ KK K + +K+K + E T +K ++K+ +
Sbjct: 708 EVKEA--PKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEG 765
Query: 864 AEFEDQDDEARVQYEG 879
+ + ++ + EG
Sbjct: 766 KPLQQEKEKEKAGGEG 781
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 53.5 bits (127), Expect = 1e-06
Identities = 75/307 (24%), Positives = 129/307 (42%), Gaps = 40/307 (13%)
Query: 436 EDESGDSDDEEDDEMSEDDGLENGSSD-------EEAEEEE---NAEMTDQYMAVKGIKR 485
E+E G ++EE+DE ++ D E G S+ EE E+EE AE + K K+
Sbjct: 152 EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKK 211
Query: 486 ---------RKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKG 536
K EL D++++ P A S + +S EE +S EE G+
Sbjct: 212 VEEKSEEVATKEELVADAKVEKPEKAKS--PVPKSPVEEKGKSPVPKSPVEE---KGKSP 266
Query: 537 ISGSKAAGEG-SKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAE---EVFASED 592
+ S +G S SP + + + KS + +KA P S A+ EV E
Sbjct: 267 VPKSPVEEKGKSPVPKSPVE-EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQ 325
Query: 593 ESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYK 652
+ EE E +++ EE + KK KP V +K + +++ + K + +
Sbjct: 326 KEEEEK----EVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHL 381
Query: 653 EENNDSKETSGALKWKEDLSRKAAEAFLRQQ---QAAPNLRK--LIYGTVTEDNEEEDDD 707
E+ ++KE L+ +++ + E ++ + A RK + E EE + +
Sbjct: 382 EK--ETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQE 439
Query: 708 TLEELGG 714
T E+ G
Sbjct: 440 TKEKGSG 446
Score = 39.3 bits (90), Expect = 0.024
Identities = 32/126 (25%), Positives = 63/126 (50%), Gaps = 10/126 (7%)
Query: 746 DLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDI 805
++EE + +I + E+ K+AA+ ++EE + E++ + P + E+
Sbjct: 92 EMEEALTAITEELAVSMKEEKKEAAE--EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 149
Query: 806 EKEVKE--EIDPDEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNR 863
EKE +E E + +E+E AK ++ KE +E +EGE +GE + +A+
Sbjct: 150 EKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE-GSSEKEEGEQE-----EGETEAEAEGEE 203
Query: 864 AEFEDQ 869
AE +++
Sbjct: 204 AEAKEE 209
Score = 36.2 bits (82), Expect = 0.21
Identities = 67/316 (21%), Positives = 119/316 (37%), Gaps = 30/316 (9%)
Query: 583 TAEEVFASEDESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIE 642
T E + ++E +E++ EE ++E EE KK P + ++ + + +E E
Sbjct: 101 TEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKK--SPVKATAPEVKEEEGEKEEEEGQE 158
Query: 643 NLLKEEE----DYKEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVT 698
+E+E D EE KE S K + + EA ++A K +
Sbjct: 159 EEEEEDEGAKSDQAEEGGSEKEGSSE-KEEGEQEEGETEAEAEGEEAEAKEEKKV----- 212
Query: 699 EDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCF 758
+ + E+ T EEL +V +P++ S + P E+ + +
Sbjct: 213 -EEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 271
Query: 759 VT--GKWEDDKDAAKVLAEDEELYGDFEDLETGDV---------HKGKSGPNTQNEDIEK 807
V GK K + + E+ V K + G Q E+ EK
Sbjct: 272 VEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK 331
Query: 808 EVKEEIDPDEEESAKK----KHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNR 863
EVKE P EE+ KK K + +K+K + E T +K ++K+ +
Sbjct: 332 EVKEA--PKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEG 389
Query: 864 AEFEDQDDEARVQYEG 879
+ + ++ + EG
Sbjct: 390 KPLQQEKEKEKAGGEG 405
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 52.4 bits (124), Expect = 3e-06
Identities = 102/456 (22%), Positives = 173/456 (37%), Gaps = 56/456 (12%)
Query: 455 GLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAE 514
GL G +E E+ E ++ ++ K KL E M + + + +E
Sbjct: 1733 GLSQGPGVDEGEDGEGSQRLNRD------KDPKLGEAEGDAMAQEREGKTHNSETSAGSE 1786
Query: 515 EGEAEEADESSEEEDCTAG-----EKGISGSKAAGEGSKAGLSPANCQSDRVNLEKSLLM 569
GEAE+ E E T G E + G AAG G QSD ++
Sbjct: 1787 LGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPG------QSDGAEGIEAPEA 1840
Query: 570 KKAALPTFDSGHCTAEEVFASEDESE---ESSSLSA---------EEEDSENEEAIRKKL 617
+ A P + E A E E E ES + A E ED E EA +
Sbjct: 1841 EGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEV- 1899
Query: 618 SKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKE-ENNDSKETSGALKWKEDLSRKAA 676
+P + + ET +E L E ED E E +++E A + E ++ +
Sbjct: 1900 -QPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPES 1958
Query: 677 EAFLRQQ---QAAP---NLRKLIYGTVTEDNEEE---DDDTLEELGGLFRVNQPDRECKH 727
E Q+ +A P ++ L T++ E E + + +E + + + E +
Sbjct: 1959 EVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQP 2018
Query: 728 KADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLE 787
++D VEA + EE + T K E D E E + ++ E
Sbjct: 2019 ESDG-------VEAQPKSEGEEAQEVEGE---TQKTEGDAQPESDGVEAPEAEEEAQEAE 2068
Query: 788 TGDVHKGKSGPNTQNEDIEKEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEG---- 843
G+V + + + ++ED++ + E E E + + + + E +A EG
Sbjct: 2069 -GEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQP 2127
Query: 844 ESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEG 879
ES + + E + Q + E +D + EA+ + EG
Sbjct: 2128 ESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEG 2163
Score = 42.7 bits (99), Expect = 0.002
Identities = 54/206 (26%), Positives = 89/206 (43%), Gaps = 19/206 (9%)
Query: 435 DEDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDS 494
+EDE+ + D EE S + L + EE + EE E T+ +G++ ++LEE
Sbjct: 1272 NEDEA-ERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEG----EGLQEEAVQLEETK 1326
Query: 495 EMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLSPA 554
+ + LE + EGE ++ +E+ EE G +G+ E K G
Sbjct: 1327 TEE--GLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEG-PEG 1383
Query: 555 NCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEAIR 614
Q + LE+ L K+ LP + G +E+ SE S + S E++ + EEA R
Sbjct: 1384 GLQGEA--LEEGL--KEEGLP--EEGSVHGQEL--SEASSPDGKG-SQEDDPVQEEEAGR 1434
Query: 615 KKLSKPSQVSSG--QKLGPQNFIDET 638
S + G + P + + ET
Sbjct: 1435 ASASAEPCPAEGTEEPTEPPSHLSET 1460
Score = 42.7 bits (99), Expect = 0.002
Identities = 73/329 (22%), Positives = 135/329 (41%), Gaps = 40/329 (12%)
Query: 363 QDEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDIDN---QGLMMPKEEKQ 419
++E P E V++L T +A+ +++P SED++ +G M EE+
Sbjct: 1967 EEEAQPESEDVEALEVEVETQEAE---------GEAQP-ESEDVEAPEAEGEMQEAEEEA 2016
Query: 420 MDLNTGRMRRKAIFGDEDES--GDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQY 477
+ G + G+E + G++ E D E DG+E ++EEA+E E +
Sbjct: 2017 QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEG-----EV 2071
Query: 478 MAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEEAD--ESSEEE-DCTAGE 534
+G E E+ + A + + + EGEA++A+ E+ E E +
Sbjct: 2072 QEAEG--EAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPES 2129
Query: 535 KGISGSKAAGEG--SKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASED 592
+GI +A GE G+ + + + + + ++A + E V A E
Sbjct: 2130 EGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE----EEAQPELEGVEAPEA 2185
Query: 593 ESE---ESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEE 649
E E ES + A E + E + + + + P Q P+ ET + E + E
Sbjct: 2186 EGEAQPESEGIEAPEAEGEAQPEL-EGVEAPEAEEEAQ---PEPEGVETPEAEGEAQPES 2241
Query: 650 DYKEENNDSKETSGALKWKEDLSRKAAEA 678
+ E K+ S + + S +A+E+
Sbjct: 2242 E--GETQGEKKGSPQVSLGDGQSEEASES 2268
Score = 42.0 bits (97), Expect = 0.004
Identities = 76/373 (20%), Positives = 143/373 (38%), Gaps = 35/373 (9%)
Query: 436 EDESGDSDDEEDDEMSEDDGLE----NGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELE 491
E E ++ + E + E + +E G + E+E E E + +G + + E+
Sbjct: 1902 ESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVI 1961
Query: 492 EDSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGL 551
E E + A +S+D E + E + E ED A E A GE +A
Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPE-------AEGEMQEAE- 2013
Query: 552 SPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEE 611
A +SD V + ++A ++ + S+ + A+E + E +E
Sbjct: 2014 EEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE 2073
Query: 612 AIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGALKWKEDL 671
A + + V + + G E+ +E E E K E ++ ET G + E
Sbjct: 2074 AEGEAHPESEDVDAQEAEGEAQ--PESEGVEAPEAEGEAQKAEGIEAPETEGEAQ-PESE 2130
Query: 672 SRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADS 731
+A EA + +A P G +D E E E + + + E + + +
Sbjct: 2131 GIEAPEA---EGEAQPESE----GVEAQDAEGEAQPESEGI----EAQEAEEEAQPELEG 2179
Query: 732 LDCSRFLVEAPH-DWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGD 790
VEAP + + + I G+ + + + + +EE + E +ET +
Sbjct: 2180 -------VEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPE 2232
Query: 791 VHKGKSGPNTQNE 803
+G++ P ++ E
Sbjct: 2233 A-EGEAQPESEGE 2244
Score = 40.8 bits (94), Expect = 0.008
Identities = 113/576 (19%), Positives = 199/576 (34%), Gaps = 147/576 (25%)
Query: 348 DKDAVYVDLGGSHVFQDEVGPTHELVQSLISTHSTIDAKMASSRVTLFSDSKPLGSEDID 407
DKD + G + Q+ G TH S S +A+ ++ ++ GS D
Sbjct: 1755 DKDPKLGEAEGDAMAQEREGKTHNSETSAGSELG--EAEQEGEGISERGETGGQGSGHED 1812
Query: 408 N-------------------QGLMMPKEEKQMDLNTGRMRRKAIFGDEDES-GDSDDEED 447
N +G+ P+ E + + + GD E+ G++ E +
Sbjct: 1813 NLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESE 1872
Query: 448 D-EMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDD 506
D E E +G S++ E E+ + + + K E + ++E + +D
Sbjct: 1873 DVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEK-EAQPETESVEALETEGED 1931
Query: 507 DLERSSAEEGEAEEA----------------------DESSEEEDCTAGEKGISGSKAAG 544
+ E AE EAEEA + E ED A E + +A G
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 545 EGSKAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEE 604
E ++ ESE+ + AE
Sbjct: 1992 E--------------------------------------------AQPESEDVEAPEAEG 2007
Query: 605 EDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDSKETSGA 664
E E EE + + S G + P++ +E ++E ++ E + +D E A
Sbjct: 2008 EMQEAEEEAQPE-------SDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEA 2060
Query: 665 LKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDDTLEELGGLFRVNQPDRE 724
+ ++ + EA + +A P E ED D E G QP+ E
Sbjct: 2061 EEEAQEAEGEVQEA---EGEAHP--------------ESEDVDAQEAEGEA----QPESE 2099
Query: 725 CKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDEELYGDFE 784
VEAP + I G+ + + + + + E + E
Sbjct: 2100 G-------------VEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE 2146
Query: 785 DLETGDVHKGKSGPNTQNEDIE-KEVKEEIDPDEEESAKKKHLDKKRKLKEMFDAEYDEG 843
+E D +G++ P ++E IE +E +EE P+ E + + + E +A EG
Sbjct: 2147 GVEAQDA-EGEAQP--ESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEG 2203
Query: 844 ESTYFDDLKGEMQKQAQLNRAEFEDQDDEARVQYEG 879
E+ Q +L E + ++EA+ + EG
Sbjct: 2204 EA------------QPELEGVEAPEAEEEAQPEPEG 2227
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 52.4 bits (124), Expect = 3e-06
Identities = 73/296 (24%), Positives = 120/296 (40%), Gaps = 54/296 (18%)
Query: 436 EDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRR-KLELEE-- 492
+DE GD +ED+E +++ +E EE +E +AE Q ++ ++R +L LEE
Sbjct: 283 DDEDGDFQPQEDEEEDDEETIEV----EEQQEGNDAEA--QRREIELLRREGELPLEELL 336
Query: 493 -----------DSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEED----CTAGEKGI 537
S P+ DSD R EEG EE + E + T K
Sbjct: 337 RSLPPQLLEGPSSPSQTPSSHDSDT---RDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQP 393
Query: 538 SGSKAAGEGSKAGLSPANCQSDRVNLEKSL------LMKKAALPTFDSGHCTAEEVFASE 591
E A A + D + E+ L M+ + L G + EE+
Sbjct: 394 WHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAR--EGELSMEELLQQY 451
Query: 592 DESEESSSLSAEEEDSENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDY 651
+ S S+E+ED + +A V + + PQ D +S +++ ED
Sbjct: 452 AGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEP--PQE--DSSSQSDSVEDRSEDE 507
Query: 652 KEENNDSKETSGALKWKEDLSRKAAEAFLRQQQAAPNLRKLIYGTVTEDNEEEDDD 707
++E+++ +ETSG+ +E S ++ +A + Q D EEEDDD
Sbjct: 508 EDEHSEEEETSGSSASEESESEESEDAQSQSQ---------------ADEEEEDDD 548
Score = 47.8 bits (112), Expect = 7e-05
Identities = 56/231 (24%), Positives = 94/231 (40%), Gaps = 15/231 (6%)
Query: 436 EDESGDSDDEEDDEMSEDDGLENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSE 495
E S S + DG E G+ E E + E+ AV ++ +ED E
Sbjct: 345 EGPSSPSQTPSSHDSDTRDGPEEGA---EEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDE 401
Query: 496 MDLPAFADSDDDLERSSAEE---GEAEEADESSE---EEDCTAGE--KGISGSKAAGEGS 547
+++D+ + +AEE GE + A E SE E + + E + +G+ A G GS
Sbjct: 402 EFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAPGSGS 461
Query: 548 KAGLSPANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDS 607
++ + E ++ P DS + SEDE +E S EEE++
Sbjct: 462 SEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHS----EEEET 517
Query: 608 ENEEAIRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEENNDS 658
A + S+ S+ + Q + D+ +E LL +E+ E + S
Sbjct: 518 SGSSASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSEADAGS 568
Score = 38.9 bits (89), Expect = 0.032
Identities = 29/120 (24%), Positives = 49/120 (40%), Gaps = 18/120 (15%)
Query: 397 DSKPLGSEDIDNQGLMMPKEEKQMDLNTGRMRRKAIFGDEDESGDSDDEEDDEMSEDDGL 456
D S D + +G + +E Q D ++ D D ++E+DE SE++
Sbjct: 468 DEVDANSSDCEPEGPVEAEEPPQEDSSS----------QSDSVEDRSEDEEDEHSEEEET 517
Query: 457 ENGSSDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEG 516
S+ EE+E EE+ + Q A E EED + + D++ + A G
Sbjct: 518 SGSSASEESESEESEDAQSQSQAD--------EEEEDDDFGVEYLLARDEEQSEADAGSG 569
Score = 32.0 bits (71), Expect = 3.9
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 10/108 (9%)
Query: 456 LENGS--SDEEAEEEENAEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDL----- 508
LE GS + +E E ++AE T + +G + L + E + ++LP A SD+ L
Sbjct: 2611 LEAGSIPNGQEQEAPDSAEGTTLTVLPEG-EELPLCVSESNGLELPPSAASDEPLQEPLE 2669
Query: 509 -ERSSAEEGEAEEADESSEE-EDCTAGEKGISGSKAAGEGSKAGLSPA 554
+R+S E EA+ S E+ ++ E + ++ S G SPA
Sbjct: 2670 ADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPA 2717
Score = 31.2 bits (69), Expect = 6.7
Identities = 32/182 (17%), Positives = 75/182 (41%), Gaps = 32/182 (17%)
Query: 696 TVTEDNEEEDDDTLEELGGLFRVNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIR 755
T E+ E+++DT+ Q + E H + + +R + +EE++
Sbjct: 404 TANEEEAEDEEDTIAA------EEQLEGEVDHAMELSELAR-----EGELSMEELLQQYA 452
Query: 756 DCFVTGKWEDDKDAAKVLAEDEELYGDFEDLETGDVHKGKSGPNTQNEDIEKEVKEEIDP 815
+ G + + +++E+ + D E + + P + V++ +
Sbjct: 453 GAYAPGSGSSEDE------DEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSED 506
Query: 816 DEEESAKKKHLDKKRKLKEMFDAEYDEGESTYFDDLKGEMQKQAQLNRAEFEDQDDEARV 875
+E+E ++++ +E +E +E E + Q Q+Q A+ E++DD+ V
Sbjct: 507 EEDEHSEEEETSGSSASEE---SESEESE---------DAQSQSQ---ADEEEEDDDFGV 551
Query: 876 QY 877
+Y
Sbjct: 552 EY 553
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 52.0 bits (123), Expect = 4e-06
Identities = 98/461 (21%), Positives = 171/461 (37%), Gaps = 91/461 (19%)
Query: 441 DSDDEEDDEMSEDDGLENGSSDEEAEEEENAE--------MTDQYMAVKGIKRRKLELEE 492
+ ED+E E + + G E++ EE++ E ++ IK+ +L
Sbjct: 158 EKSQREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARS 217
Query: 493 DSEMDLPAFADSDDDLERSSAEEGEAEEADESSEEEDCTAGEKGISGSKAAGEGSKAGLS 552
++ + E+SS E GE + E+ +E G + E S+ G
Sbjct: 218 ETHA-AGHSQEKTHSREKSSQESGEETGSQENHPQES--------KGQPRSQEESEEGEE 268
Query: 553 PANCQSDRVNLEKSLLMKKAALPTFDSGHCTAEEVFASEDESEESSSLSAEEEDSENEEA 612
A + D K+ P G + D S + SL +EE+ EE+
Sbjct: 269 DATSEVD----------KRRTRPRHHHGR-------SRPDRSSQGGSLPSEEKGHPQEES 311
Query: 613 IRKKLSKPSQVSSGQKLGPQNFIDETSDIENLLKEEEDYKEE--NNDSKETSGALKWKED 670
+ S S S G+K D S +EE +Y EE + L+W+
Sbjct: 312 ---EESNVSMASLGEKR------DHHSTHYRASEEEPEYGEEIKGYPGVQAPEDLEWERY 362
Query: 671 LSRKAAEAFLRQQQAAPN-------------LRKLIYGTVTEDNEEEDDDTLEELGGLFR 717
R + E + Q+ + L K+ +G E EE + + G R
Sbjct: 363 RGRGSEEYRAPRPQSEESWDEEDKRNYPSLELDKMAHGYGEESEEERGLEPGK--GRHHR 420
Query: 718 VNQPDRECKHKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTGKWEDDKDAAKVLAEDE 777
+ +D+ + RFL E H E M+ R + A K L +
Sbjct: 421 GRGGEPRAYFMSDTREEKRFLGEGHHRVQ-ENQMDKAR--------RHPQGAWKELDRNY 471
Query: 778 ELYGDFEDLETGDVHKGKSGPNTQNEDIE--KEVKEEIDPDEEESAKKKHLDKKRKLKEM 835
YG+ +G G Q D++ KE +EE +++ + +K+++L E+
Sbjct: 472 LNYGE----------EGAPGKWQQQGDLQDTKENREEARFQDKQYSSHHTAEKRKRLGEL 521
Query: 836 FDAEYD--EGESTYFDD--------LKGEMQKQAQLNRAEF 866
F+ YD + +S++F+ L+GE + + LN F
Sbjct: 522 FNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNF 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,623,402
Number of Sequences: 37866
Number of extensions: 2528077
Number of successful extensions: 29614
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 269
Number of HSP's successfully gapped in prelim test: 759
Number of HSP's that attempted gapping in prelim test: 14282
Number of HSP's gapped (non-prelim): 9153
length of query: 1282
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1168
effective length of database: 13,930,794
effective search space: 16271167392
effective search space used: 16271167392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.