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Search of human proteins with 224586875
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224586875 coiled-coil domain containing 65 [Homo sapiens]
(484 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224586875 coiled-coil domain containing 65 [Homo sapiens] 942 0.0
gi|217416374 hypothetical protein LOC92749 [Homo sapiens] 84 4e-16
gi|100814339 coiled-coil domain containing 146 [Homo sapiens] 68 2e-11
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 67 3e-11
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 67 3e-11
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 67 4e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 65 1e-10
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 65 2e-10
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 64 2e-10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 64 3e-10
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 63 7e-10
gi|71061468 centromere protein E [Homo sapiens] 62 1e-09
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 62 2e-09
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 62 2e-09
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 61 2e-09
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 61 2e-09
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 59 8e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 1e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 1e-08
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 59 1e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 58 2e-08
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 57 3e-08
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 57 3e-08
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 57 3e-08
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 57 3e-08
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 57 3e-08
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 57 3e-08
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 57 3e-08
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 57 4e-08
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 57 4e-08
>gi|224586875 coiled-coil domain containing 65 [Homo sapiens]
Length = 484
Score = 942 bits (2436), Expect = 0.0
Identities = 484/484 (100%), Positives = 484/484 (100%)
Query: 1 MPKKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNK 60
MPKKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNK
Sbjct: 1 MPKKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNK 60
Query: 61 INTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSH 120
INTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSH
Sbjct: 61 INTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSH 120
Query: 121 LHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQ 180
LHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQ
Sbjct: 121 LHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQ 180
Query: 181 NYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDR 240
NYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDR
Sbjct: 181 NYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDR 240
Query: 241 KAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELV 300
KAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELV
Sbjct: 241 KAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELV 300
Query: 301 LVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEE 360
LVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEE
Sbjct: 301 LVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEE 360
Query: 361 EKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQH 420
EKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQH
Sbjct: 361 EKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQH 420
Query: 421 RRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAHPGDKQ 480
RRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAHPGDKQ
Sbjct: 421 RRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAHPGDKQ 480
Query: 481 HPTT 484
HPTT
Sbjct: 481 HPTT 484
>gi|217416374 hypothetical protein LOC92749 [Homo sapiens]
Length = 740
Score = 83.6 bits (205), Expect = 4e-16
Identities = 65/316 (20%), Positives = 148/316 (46%), Gaps = 1/316 (0%)
Query: 6 KMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQW 65
K+AK L + + Q + E + +E + + +KL E S ++I ++W
Sbjct: 82 KLAKLLLCGTELVTNIQVAIDIREIHRRVEEEEIKRQRIEKLENEVKTSQDKFDEITSKW 141
Query: 66 RTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVD 125
++ +EL + + +++ K+ +I L ++L ++QY L+ ++
Sbjct: 142 EEGKQKRIPQELWEMLNTQQLHCAGLLEDKNKLISELQQELKTKDDQYVKDLKKQSDDIC 201
Query: 126 QLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDS 185
LL ++ + +++ EL + K FE ER+ ++ ++K+ A E Y+++
Sbjct: 202 LLLERMEEQVKNVMKTFREELYNIEKAFEVERQELLASNKKKWEQALQAHNAKELEYLNN 261
Query: 186 EYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFE 245
+ +++ N + + EE + +++ LE V+ L ++ Q Y E + +
Sbjct: 262 RMKKVEDYEKQLNRQRIWDCEEYNMIKIKLEQDVQILEQQLQQRKAIYQLNQEKLEYNLQ 321
Query: 246 TLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLR 305
L+ +DE+S+ Q +KI +L D + + K ++ ++EN+ + +D + +++Q +
Sbjct: 322 VLKKRDEESTVIKSQQKRKINRLHDILNNLRSKYAKQIKQFQEENQSLTSDYKRLVMQFK 381
Query: 306 KL-KAQRTQARAASQK 320
+L KA R A +K
Sbjct: 382 ELQKAMRHFALIDDEK 397
>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
Length = 955
Score = 68.2 bits (165), Expect = 2e-11
Identities = 107/495 (21%), Positives = 216/495 (43%), Gaps = 78/495 (15%)
Query: 5 EKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDK---LAKEEHNSALNLNKI 61
EK+ + + EK+ ++ +Q++ + KK E +S + +K + + E AL +
Sbjct: 246 EKITRKKVEMEKKKIVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEGKRAL----L 301
Query: 62 NTQWRTVLREVKTRELHKDIEILSQTFERVVDC--------KDNVIKSLAKDLSEAEEQY 113
+ R + VK EL ++ E S T ++D K N L++ E E +
Sbjct: 302 EIKEREHNQLVKLLELARENEATSLTERGILDLNLRNSLIDKQNYHDELSRKQREKERDF 361
Query: 114 AHALRSHLHNVDQLLALQRHRL---SLLEESYNMELEALTKEFETERKTIIDQHEKEIHY 170
+L ++ LL + L L + +E+EA+ K+ T + + +E+H
Sbjct: 362 -----RNLRKMELLLKVSWDALRQTQALHQRLLLEMEAIPKDDST-----LSERRRELHK 411
Query: 171 LQDIFMA-MEQNYIDSEYESKLEFQSMWNDLKNMNLEEK------HFLRLHLENRVEDLW 223
++ + Q I SE ESKL Q + + K + +E + LR+ + ++++
Sbjct: 412 EVEVAKRNLAQQKIISEMESKLVEQQLAEENKLLKEQENMKELVVNLLRM-TQIKIDEKE 470
Query: 224 RKFQDVLK---NYTDATEDRKAAFETLQVKDEKSSK-EIEVQMKKIQKLQDAITISKGKI 279
+K +D LK YT+ ++ KA + L+++ K K EI ++++ KL D
Sbjct: 471 QKSKDFLKAQQKYTNIVKEMKA--KDLEIRIHKKKKCEIYRRLREFAKLYDT-------- 520
Query: 280 MIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKI 339
IRN++ + L K + + + + +L L + N+ + RK+
Sbjct: 521 -------------IRNERNKFVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQERKL 567
Query: 340 VDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYI 399
+ +LK A E+ + V S + KE++ Q NN++ L +T + + +
Sbjct: 568 QN---SMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMV 624
Query: 400 GMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIV 459
+ KRY K ++QHR + + + E+ Y + I++ +++ +LN +
Sbjct: 625 QLR---KRYEK------AVQHRNESGVQLIEREEEICIFY-EKINIQEKM--KLNGEIEI 672
Query: 460 NYQSNLLQPLSIRIA 474
+ +Q L ++IA
Sbjct: 673 HLLEEKIQFLKMKIA 687
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 67.4 bits (163), Expect = 3e-11
Identities = 100/452 (22%), Positives = 192/452 (42%), Gaps = 46/452 (10%)
Query: 13 SDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREV 72
SD KQ + ++L E AK++ + Q D L LNK Q + + E
Sbjct: 497 SDSKQHI----EVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEK 552
Query: 73 KTR--ELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAH------ALRSHLHNV 124
T+ E+H D++ + ER V+ I++L + L + E+Q + +L++ N
Sbjct: 553 GTQAGEIH-DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNT 611
Query: 125 DQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYID 184
D L L+ E + E ++ E E++ ID ++K++ L++ ++ + +
Sbjct: 612 DTALTTLEEALAEKERTIERLKEQRDRD-EREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 670
Query: 185 SEYESKLEFQSMWNDLKNMNLEEKHFLR---LHLENRVEDLWRKFQDVLKNYTDATEDRK 241
E S L+ + + L + L++ L+ + LE + E+ + + K + A E R
Sbjct: 671 KE-ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA 729
Query: 242 AAF----------ETLQVKDEKSSKEIEVQ--MKKIQKLQDAITISKGKIMIHSRESEDE 289
+ E + KDE S + EV ++ ++++++ KI R+ +D+
Sbjct: 730 SPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQ 789
Query: 290 NRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKL 349
N+ + N K V+ +K +AR L S +LRK D+ E++ +
Sbjct: 790 NKKVANLKHKEQVEKKKSAQMLEEARRRED----NLNDSSQQLQDSLRKKDDRIEELEEA 845
Query: 350 AEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYN 409
+ E E VL S T E++ +EEL + KV + M+
Sbjct: 846 LRESVQITAEREMVLAQEESARTNAEKQ------VEELLMAMEKVKQELESMK------A 893
Query: 410 KVKLEQLSLQHRRAQLLDINGKLREMLKQYLD 441
K+ Q SL + L ++ + R+ L++ L+
Sbjct: 894 KLSSTQQSLAEKETHLTNLRAERRKHLEEVLE 925
Score = 53.1 bits (126), Expect = 5e-07
Identities = 73/401 (18%), Positives = 162/401 (40%), Gaps = 44/401 (10%)
Query: 22 QQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELH--- 78
Q + A ++ + + L F +D ++ L + N Q E + +EL
Sbjct: 226 QMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLR 285
Query: 79 ---KDIEILSQTFERVVDCKDNVIKSLAKDLSE-------AEEQYAHALR-----SHLHN 123
+++E+ +T ++ ++ +D IK L + L EE + R H+H+
Sbjct: 286 KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHH 345
Query: 124 VDQLLALQRHRLSLLEESYNMELEALTKEFETER-KTIIDQHEKEIHYLQDIFMAMEQNY 182
++ LL + S+L E + E +T+ +T+I+ + +I ++ +E+
Sbjct: 346 LESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEI 405
Query: 183 IDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKA 242
+ L + ++K M + H ++N+VE L + ++A
Sbjct: 406 QMLKSNGALSTEEREEEMKQMEVYRSH--SKFMKNKVEQL-----------KEELSSKEA 452
Query: 243 AFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLV 302
+E L+ K EI +++ + + + K+ + + D ++I KE +
Sbjct: 453 QWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTA 512
Query: 303 QLRKLKAQRTQARAASQKNLVRLTLESNATL--KALRKIVD----KGEKILKLAEICRKF 356
+ ++ +T+ A +RL LE T+ K ++I D KG + ++ ++
Sbjct: 513 KEQRAAILQTEVDA------LRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML 566
Query: 357 ETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVD 397
+ +E KV + +EQ ++ + L E + + D
Sbjct: 567 DVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAD 607
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 67.4 bits (163), Expect = 3e-11
Identities = 100/452 (22%), Positives = 192/452 (42%), Gaps = 46/452 (10%)
Query: 13 SDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREV 72
SD KQ + ++L E AK++ + Q D L LNK Q + + E
Sbjct: 469 SDSKQHI----EVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEK 524
Query: 73 KTR--ELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAH------ALRSHLHNV 124
T+ E+H D++ + ER V+ I++L + L + E+Q + +L++ N
Sbjct: 525 GTQAGEIH-DLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNT 583
Query: 125 DQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYID 184
D L L+ E + E ++ E E++ ID ++K++ L++ ++ + +
Sbjct: 584 DTALTTLEEALAEKERTIERLKEQRDRD-EREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 642
Query: 185 SEYESKLEFQSMWNDLKNMNLEEKHFLR---LHLENRVEDLWRKFQDVLKNYTDATEDRK 241
E S L+ + + L + L++ L+ + LE + E+ + + K + A E R
Sbjct: 643 KE-ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARA 701
Query: 242 AAF----------ETLQVKDEKSSKEIEVQ--MKKIQKLQDAITISKGKIMIHSRESEDE 289
+ E + KDE S + EV ++ ++++++ KI R+ +D+
Sbjct: 702 SPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQ 761
Query: 290 NRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKL 349
N+ + N K V+ +K +AR L S +LRK D+ E++ +
Sbjct: 762 NKKVANLKHKEQVEKKKSAQMLEEARRRED----NLNDSSQQLQDSLRKKDDRIEELEEA 817
Query: 350 AEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYN 409
+ E E VL S T E++ +EEL + KV + M+
Sbjct: 818 LRESVQITAEREMVLAQEESARTNAEKQ------VEELLMAMEKVKQELESMK------A 865
Query: 410 KVKLEQLSLQHRRAQLLDINGKLREMLKQYLD 441
K+ Q SL + L ++ + R+ L++ L+
Sbjct: 866 KLSSTQQSLAEKETHLTNLRAERRKHLEEVLE 897
Score = 50.1 bits (118), Expect = 5e-06
Identities = 82/422 (19%), Positives = 161/422 (38%), Gaps = 53/422 (12%)
Query: 20 LFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHK 79
L ++ + +E + F +L KE +KI T W+ R V+ H
Sbjct: 167 LLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKI-TIWKEQYRVVQEENQHM 225
Query: 80 DIEI------------LSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHA----------- 116
+ I L+Q F++ D + +L+E Q HA
Sbjct: 226 QMTIQALQDELRIQRDLNQLFQQ--DSSSRTGEPCVAELTEENFQRLHAEHERQAKELFL 283
Query: 117 LRSHLHNVDQLLALQRHRLSLLEESYNMELEALTK--------EFETERKTIIDQHEKEI 168
LR L ++ + Q+ L+ +ES LE L E + ER + + E +
Sbjct: 284 LRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHV 343
Query: 169 HYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNL----EEKHFLRLHLENRVEDLWR 224
H+L+ + E+ E F++ + K L E K +E + DL
Sbjct: 344 HHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEE 403
Query: 225 KFQDVLKNYTDATEDRKAAFETLQVKDEKSS---KEIEVQMKKIQKLQDAITISKGKIMI 281
+ Q + N +TE+R+ + ++V S +I +++ + + + K+
Sbjct: 404 EIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLET 463
Query: 282 HSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATL--KALRKI 339
+ + D ++I KE + + ++ +T+ A +RL LE T+ K ++I
Sbjct: 464 LTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDA------LRLRLEEKETMLNKKTKQI 517
Query: 340 VD----KGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVM 395
D KG + ++ ++ + +E KV + +EQ ++ + L E + +
Sbjct: 518 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 577
Query: 396 VD 397
D
Sbjct: 578 AD 579
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 67.0 bits (162), Expect = 4e-11
Identities = 103/454 (22%), Positives = 196/454 (43%), Gaps = 78/454 (17%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAK-EEHNSALNLNKI 61
K E++ KT S ++L +K L EEE K+ RL + L+ ++++ E+ A + +K
Sbjct: 393 KDEEITKTE-SQCREL----RKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKS 447
Query: 62 N-TQWRTVLREVK--TRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALR 118
TQ L + K T++L ++E V+KS K+L +E + A
Sbjct: 448 ECTQLHLNLEKEKNLTKDLLNELE---------------VVKSRVKELECSESRLEKA-- 490
Query: 119 SHLHNVDQLLALQRHRLSLLEESYNM---------ELEALTKEFETERKTIIDQHEKEIH 169
L D L L+ + L++E NM +++ L K F+ E+ ++D EK I
Sbjct: 491 -ELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIE 549
Query: 170 YLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDV 229
+ + + SE E K+ + D L+ + L V+ L ++ +
Sbjct: 550 ESKKLLK------LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGI 603
Query: 230 LKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDE 289
+ + T R L ++ KE+ +++++++K + + +G +M ++EDE
Sbjct: 604 EEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLM----KTEDE 659
Query: 290 NRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKL 349
+ +K + ++ +A SQ+ LE A K ++KGE + +
Sbjct: 660 YDQLE----------QKFRTEQDKANFLSQQ------LEEIKHQIAKNKAIEKGEVVSQE 703
Query: 350 AEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDY-IGMENFWKRY 408
AE+ +F EE K + V KE + + L ++L+++ VDY + + F +
Sbjct: 704 AELRHRFRLEEAKSRDLKAEVQALKE----KIHELMNKEDQLSQLQVDYSVLQQRFMEEE 759
Query: 409 NK-----------VKLEQLSLQHRRAQLLDINGK 431
NK K +LS ++ RA +NG+
Sbjct: 760 NKNKNMGQEVLNLTKELELSKRYSRALRPSVNGR 793
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 65.1 bits (157), Expect = 1e-10
Identities = 77/384 (20%), Positives = 166/384 (43%), Gaps = 31/384 (8%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVK 73
+ +LLL QQ+L AE + K+ + +S L+ ++ + E + LN + WR +E K
Sbjct: 313 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR---QEEK 369
Query: 74 TRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRH 133
+E +E + ++ I+ + + E EE+ + ++ + Q
Sbjct: 370 IQE-----------WEEKIQEQEEKIREQEEKIREQEEKMRRQ-EEMMWEKEEKMRRQEE 417
Query: 134 RLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEF 193
+ EE + E + ++ E R+ HE+E Q+ E+ + E + E
Sbjct: 418 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE- 476
Query: 194 QSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEK 253
MW + + +E+ + + E +WR+ + + + E+++ E + ++EK
Sbjct: 477 AKMWRQEEKIREQEE-----KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 531
Query: 254 SSKEIEV--QMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQR 311
++ E+ Q +KI + ++ I + K+ + D+ IR +E V Q K++ Q
Sbjct: 532 IREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591
Query: 312 TQARAASQKNLVRLTLESNATLKALRKIVDKGEKIL----KLAEICRKFETEEEKVLPFY 367
+ R +K + + T + K+ ++ EK+ K+ E K +EEK+
Sbjct: 592 EKIREQEEK----IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Query: 368 SSVLTPKEQEGIQKNNLEELTEEL 391
+ +E+ Q+ ++E E++
Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKM 671
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 64.7 bits (156), Expect = 2e-10
Identities = 97/475 (20%), Positives = 206/475 (43%), Gaps = 64/475 (13%)
Query: 8 AKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRT 67
A++ LS K+ + K E+ K+ L ++ ++L + +A+NL K + Q R+
Sbjct: 1445 AESELSCTKE----KTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRS 1500
Query: 68 VLREVKTRELH--KDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVD 125
+ + K E H K EIL + ++V KD+ + L+K +E+ L+ +++
Sbjct: 1501 LQADAKDLEQHKIKQEEILKE-INKIVAAKDSDFQCLSK----KKEKLTEELQKLQKDIE 1555
Query: 126 QLLALQRHRLSLLEES------YNMELEALTKEFETERK--TIIDQ---HEK-EIHYLQD 173
+ H L +L+ES ELE L + ++++ ++D+ H+K E+H LQ
Sbjct: 1556 MAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQG 1615
Query: 174 IFMAMEQNYIDS----------------EYESKLEFQSMWNDLKNMNLEEKHFLRLHLEN 217
+ + + ++ E +S LE S N+ + E+ ++
Sbjct: 1616 SMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQ 1675
Query: 218 RVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKG 277
+E Q VL+ + + K + LQ+++ E+Q K+Q Q + K
Sbjct: 1676 EIEKEEENLQVVLRQMSKHKTELKNILDMLQLENH------ELQGLKLQHDQRVSELEKT 1729
Query: 278 KIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALR 337
++ + + E EN + ++ ++ +K +R ++ + R+T ES A +
Sbjct: 1730 QVAVLEEKLELENLQQISQQQKGEIEWQKQLLER------DKREIERMTAESRALQSCVE 1783
Query: 338 KIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVM-- 395
+ + E + + +I K + ++VL +E ++++NLE+L + K+
Sbjct: 1784 CLSKEKEDLQEKCDIWEKKLAQTKRVL------AAAEENSKMEQSNLEKLELNVRKLQQE 1837
Query: 396 VDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVL 450
+D + + +N + Q LQ +R + L+E L D ++++ + L
Sbjct: 1838 LDQLNRDKL-SLHNDISAMQQQLQEKREAV----NSLQEELANVQDHLNLAKQDL 1887
Score = 50.1 bits (118), Expect = 5e-06
Identities = 75/358 (20%), Positives = 150/358 (41%), Gaps = 48/358 (13%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSAL------ 56
+KE+ ++ + ++ L +Q+ E+E+ +K +L Q L LA EE L
Sbjct: 1954 QKERESEESKLETSKVTLKEQQHQLEKELTDQKSKL-DQVLSKVLAAEERVRTLQEEERW 2012
Query: 57 --NLNKINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYA 114
+L K +Q + L E + + + K E+L+ E S+ D S Q+
Sbjct: 2013 CESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEA---------DSMRADFSLLRNQFL 2063
Query: 115 HALRS---HLHNVDQLLALQRHRL--SLLEESYNMELEALTKEFETERKTIIDQHEKEIH 169
+ + ++ + L +QR +L +LLE+ E + KE T D HE+
Sbjct: 2064 TERKKAEKQVASLKEALKIQRSQLEKNLLEQK--QENSCIQKEMATIELVAQDNHERARR 2121
Query: 170 YLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDV 229
++++ N + EY + + DL+ +E +R L++ V+D + +
Sbjct: 2122 LMKEL------NQMQYEYTELKKQMANQKDLERRQMEISDAMRT-LKSEVKD---EIRTS 2171
Query: 230 LKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQ------KLQDAITISKGKIMIHS 283
LKN + A E + ++E E+E + + ++ + S+ IM
Sbjct: 2172 LKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDEH 2231
Query: 284 RESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVD 341
E +R+ ++ + QLR +++ + L++ ++ TL +LR+ VD
Sbjct: 2232 WRGEALREKLRHREDRLKAQLRHCMSKQAEV-------LIKGKRQTEGTLHSLRRQVD 2282
Score = 45.4 bits (106), Expect = 1e-04
Identities = 91/414 (21%), Positives = 173/414 (41%), Gaps = 53/414 (12%)
Query: 4 KEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEH--NSALNLNKI 61
K + K S+EK+ +L A+ + + LL Q LKD H + + ++
Sbjct: 752 KNALGKAQFSEEKEQE--NSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEV 809
Query: 62 NTQWRTVLREVKT----RELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHAL 117
+ + R++K +H ++L ++ + D + + LA+ E +E
Sbjct: 810 AARVDELRRKLKLGTGEMNIHSPSDVLGKS---LADLQKQFSEILARSKWERDEAQVRER 866
Query: 118 RSHLHNVDQLLALQRHRLSLLEESYNME----LEALTKEFETERKTIIDQHEKEIHYLQD 173
+ + + +ALQ+ +L+ +E + LEA + + + I Q E EIHYLQ+
Sbjct: 867 K-----LQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQE 921
Query: 174 IFMAME--QNYIDSE-YESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVL 230
+ME Q D + E+ E + + L+ + ++K + +V L ++ + +
Sbjct: 922 NLKSMEEIQGLTDLQLQEADEEKERILAQLRELE-KKKKLEDAKSQEQVFGLDKELKKLK 980
Query: 231 KNYTDATEDRKAAFETLQVKDEKSSKE---IEVQMKKIQKLQDAITISKGKIMIHSRESE 287
K AT D+ A E KD+ S +++ ++ ++LQ+A S+ + ++
Sbjct: 981 K--AVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSR-------KAAQ 1031
Query: 288 DENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKIL 347
R + E+ L+Q L+ + Q R +K V S +I
Sbjct: 1032 AARDLTRAEAEIELLQ-NLLRQKGEQFRLEMEKTGVGTGANSQVL------------EIE 1078
Query: 348 KLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMV--DYI 399
KL E + TE ++ LT + +G +N LEE+ E +V DYI
Sbjct: 1079 KLNETMERQRTEIARLQNVLD--LTGSDNKGGFENVLEEIAELRREVSYQNDYI 1130
Score = 43.5 bits (101), Expect = 4e-04
Identities = 71/331 (21%), Positives = 152/331 (45%), Gaps = 40/331 (12%)
Query: 28 EEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKIN----TQWRTVLREVKTRELHKDIEI 83
++++ +K+E + S L+++LA + + LNL K + T+ + VL +TR L KDI
Sbjct: 1856 QQQLQEKREAVNS--LQEELANVQDH--LNLAKQDLLHTTKHQDVLLSEQTR-LQKDISE 1910
Query: 84 LSQTFE---RVVDCKDNVIKSLAKDLSEAE----EQYAHALRSHLHNVDQLLALQRHRLS 136
+ FE + + K ++ L ++ E + +Q R + L+ +++
Sbjct: 1911 WANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVT 1970
Query: 137 LLEESYNMELEALTKEFETERKTIIDQ-------HEKEIHYLQDIFMAMEQNYIDSEYES 189
L E+ + +E E T++K+ +DQ E+ + LQ+ E+ + +S ++
Sbjct: 1971 LKEQQHQLEKEL------TDQKSKLDQVLSKVLAAEERVRTLQE-----EERWCESLEKT 2019
Query: 190 KLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQV 249
+ + ++ + L EK L L+ + + F +L+N TE +KA + +
Sbjct: 2020 LSQTKRQLSE-REQQLVEKSGELLALQKEADSMRADFS-LLRNQF-LTERKKAEKQVASL 2076
Query: 250 KDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKA 309
K+ + +++ +++ Q+ I K I ++ R R KEL +Q +
Sbjct: 2077 KEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTEL 2136
Query: 310 QRTQARAASQKNLVRLTLESNATLKALRKIV 340
++ + A+QK+L R +E + ++ L+ V
Sbjct: 2137 KK---QMANQKDLERRQMEISDAMRTLKSEV 2164
Score = 38.9 bits (89), Expect = 0.011
Identities = 88/424 (20%), Positives = 174/424 (41%), Gaps = 74/424 (17%)
Query: 22 QQKLLAEEEMAKKKERLLSQFL-KDKLAK-------------EEHNSALNLNKINTQWRT 67
++K++ EE+ K+ R L + +DKL K EE S LN + +T
Sbjct: 280 EKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKT 339
Query: 68 VLREVKTRELHKDIEILSQTFERVVDCKD---NVIKSLAKDLSEAEEQYAHALRSHLHN- 123
+ TR K E+ + +D K N S ++ +A ++ + +S
Sbjct: 340 I---ELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKAPDESPYIGKSRYKRN 396
Query: 124 --------VDQLLALQRHRLSLLEESYNMELEA-----LTKEFETERKTI---------- 160
+D A+Q ++ E+ N + L + E + K I
Sbjct: 397 MFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSEL 456
Query: 161 ---IDQHEKEIHYLQDIFMAME---QNYIDSEYESKLEFQSMWNDLKNMNL--EEKHFLR 212
I++ E++I + F +E Q SE L ++ + L+ +N +E L
Sbjct: 457 HDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLE 516
Query: 213 LHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAI 272
L +E + +++ K +++ +D + A ++L KD K S ++ +K K Q
Sbjct: 517 LQMEKQKQEIAGKQKEI--------KDLQIAIDSLDSKDPKHS---HMKAQKSGKEQQLD 565
Query: 273 TISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNAT 332
++K + SR E +R + +E+ + L+ Q T+ + A+ + L + +
Sbjct: 566 IMNKQYQQLESRLDEILSRIAKETEEI-----KDLEEQLTEGQIAANEALKK---DLEGV 617
Query: 333 LKALRKIVD--KGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEE 390
+ L++ + KG+ E CRK E+E +L + V ++Q I + E + +E
Sbjct: 618 ISGLQEYLGTIKGQATQAQNE-CRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKE 676
Query: 391 LTKV 394
L ++
Sbjct: 677 LAEL 680
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 64.3 bits (155), Expect = 2e-10
Identities = 103/491 (20%), Positives = 203/491 (41%), Gaps = 88/491 (17%)
Query: 4 KEKMAKTPLS----DEKQLLLFQQK------LLAEEEMAKKKERLLSQFLKDKLA----- 48
KE++AKT +EK + L Q+K + AE + E Q +K K+
Sbjct: 864 KEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKI 923
Query: 49 KEEHNSALNLNKINTQWRTVLREVKTR--ELHKDIEILSQTFERVVDCK---DNVIKSLA 103
KE A + +IN + R+++ EL KDI+ L T +V K +N +K+L
Sbjct: 924 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 983
Query: 104 KDLSEAEEQYAHALR-------SHLHNVDQLLALQRHRLSLLEESYNME--LEALTKEFE 154
++++ +E A + +H +D L A + +L + +E ++ L E
Sbjct: 984 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1043
Query: 155 TERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMN--LEEKHFLR 212
E+K +D + D+ +A E +D E ND + ++ L++K F
Sbjct: 1044 QEKKIRMDLERAKRKLEGDLKLAQEST-MDIE-----------NDKQQLDEKLKKKEFEM 1091
Query: 213 LHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAI 272
L++++ED + L ++ +K KE++ +++++++ +A
Sbjct: 1092 SGLQSKIEDE----------------------QALGMQLQKKIKELQARIEELEEEIEAE 1129
Query: 273 TISKGKIMIH----SRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLE 328
S+ K SRE E+ + + Q+ K + + + +++L TL+
Sbjct: 1130 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM-RRDLEEATLQ 1188
Query: 329 SNATLKALRK-----IVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNN 383
AT LRK + + GE+I L + +K E E+ ++ + + E K N
Sbjct: 1189 HEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGN 1248
Query: 384 LEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGI 443
LE++ L + +++K ++ Q L +L+ +Y +
Sbjct: 1249 LEKMCRALE-------------DQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL 1295
Query: 444 SVSDEVLSQLN 454
D ++SQL+
Sbjct: 1296 DEKDTLVSQLS 1306
Score = 38.9 bits (89), Expect = 0.011
Identities = 89/458 (19%), Positives = 181/458 (39%), Gaps = 61/458 (13%)
Query: 27 AEEEMAKKKERLLSQFLKD-------------KLAKEEHNSALNLNKINTQWRTVLREVK 73
A+ EM KK+E + +D L K+ +S L + + V ++++
Sbjct: 1163 AQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLE 1222
Query: 74 TR--ELHKDIEILSQTFERVVDCKDNVIK---SLAKDLSEAEEQYAHALRSHLHNVDQLL 128
E+ +I+ L+ E V K N+ K +L LSE + + R ++ L
Sbjct: 1223 KEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRL----INDLT 1278
Query: 129 ALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYE 188
A QR RL Y+ +L+ E+ T++ Q + Q +E+ + + E
Sbjct: 1279 A-QRARLQTESGEYSRQLD--------EKDTLVSQLSRG---KQAFTQQIEE--LKRQLE 1324
Query: 189 SKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQ 248
+++ +S + + LR E ++ + Q + + +ET
Sbjct: 1325 EEIKAKSALAHALQSSRHDCDLLREQYEEE-QEAKAELQRAMSKANSEVAQWRTKYETDA 1383
Query: 249 VKDEKSSKEIEVQMKKI-QKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKL 307
++ ++E+E KK+ Q+LQDA + + E + ++N+ E +++ + +
Sbjct: 1384 IQ---RTEELEEAKKKLAQRLQDAEEHVEA-VNAKCASLEKTKQRLQNEVEDLMIDVERT 1439
Query: 308 KAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFY 367
A A Q+N ++ E + ++ +K R TE K+ Y
Sbjct: 1440 NAA-CAALDKKQRNFDKILAEWKQKCEETHAELEASQKE------SRSLSTELFKIKNAY 1492
Query: 368 SSVLTPKEQEGIQKNNLEELTEELTKVMVD----YIGMENFWKRYNKVKLE--------Q 415
L E + NL++ +LT+ + + +E K+ + K E +
Sbjct: 1493 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAE 1552
Query: 416 LSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQL 453
SL+H ++L I +L ++ + I+ DE + Q+
Sbjct: 1553 ASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQM 1590
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 63.9 bits (154), Expect = 3e-10
Identities = 103/489 (21%), Positives = 200/489 (40%), Gaps = 67/489 (13%)
Query: 15 EKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKT 74
E+QL QQKLL ++ ++ L Q + + K++ + L+ +KI Q E +
Sbjct: 818 EEQLAQLQQKLL---DLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQN 874
Query: 75 RELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHR 134
E+ + ++ L+Q +E S +D ++ +EQ Q+L + +
Sbjct: 875 SEMEQKVKSLTQVYE-----------SKLEDGNKEQEQ-----------TKQILVEKENM 912
Query: 135 LSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQ 194
+ + E E+E LT++ + E IH L + + +N + K + +
Sbjct: 913 ILQMREGQKKEIEILTQKLSAK--------EDSIHILNEEYETKFKNQEKKMEKVKQKAK 964
Query: 195 SMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKS 254
M LK L+++ L+ LEN +L +K + + + A + E +
Sbjct: 965 EMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETN 1024
Query: 255 SKEIEVQMKKI--QKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRT 312
KE + ++ ++L D I+I + K+ + E ++ + +KE + +L++
Sbjct: 1025 QKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFG 1084
Query: 313 QARAASQKNLVRLT---LESNATLKALR-KIVDKGEKILKLAEICRKFETEEEKVLPFYS 368
+ K + L ++ + TL L+ ++ K + LA+ K + EK+ +
Sbjct: 1085 CEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLN 1144
Query: 369 SVLTPKEQEGIQ-------------KNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQ 415
L KE +Q K + ELT +L ++ +++ ++ NK LE
Sbjct: 1145 KSL--KENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK-SLED 1201
Query: 416 LSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAH 475
SL+ + KL E L LD E L + ++N S+ + RI+H
Sbjct: 1202 KSLEFK---------KLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISH 1252
Query: 476 PGDKQHPTT 484
QH TT
Sbjct: 1253 ---CQHRTT 1258
Score = 59.3 bits (142), Expect = 8e-09
Identities = 100/482 (20%), Positives = 216/482 (44%), Gaps = 46/482 (9%)
Query: 4 KEKMAKTPLSDEKQLLLFQQKLLA---------EEEMAKKKERLLSQFLKDKLAKEEHNS 54
+E++AK EK+L +Q+L +E+M E+ S++LK KE+ S
Sbjct: 475 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 534
Query: 55 ALNLNKINTQWRTVLREVKTRELHKDIEILSQTFE-RVVDCKDNVIKSLAKDLSEAEEQY 113
L L ++ Q + +L E + + +D++ ++T+ R+++ + ++ KSL ++ +++++
Sbjct: 535 -LALEELELQKKAILTESENKL--RDLQQEAETYRTRILELESSLEKSLQENKNQSKDLA 591
Query: 114 AHA-LRSHLHNVDQLLALQRHRLSLLEESYNME------LEALTKEFETERKTIIDQHEK 166
H + HN + + +++H+ L + + L+ L ++++TE + + ++ E+
Sbjct: 592 VHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQ 651
Query: 167 EIHYLQDIFMAMEQNYIDSEYESKLE-FQSMWNDLKNMNLEEKHFL--RLHLENRVEDLW 223
E L + Q +I+ E LE +L++++ E L R LE + L
Sbjct: 652 EKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVL- 710
Query: 224 RKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQK-LQDAITISKGKIMIH 282
+ D +K +A D + QV + KE EV +++ +K L+D I + +
Sbjct: 711 KDQTDKMKQELEAKMDEQKNHHQQQV--DSIIKEHEVSIQRTEKALKDQINQLELLLKER 768
Query: 283 SRESEDENRYIRNDKELVL-----VQLRKLKAQRTQARAASQKNLVRLTLESNATLKALR 337
+ ++ ++ N + + +Q K Q+ ++ + E A L+ +
Sbjct: 769 DKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQ--Q 826
Query: 338 KIVDKGEKILKLAEICRKFETEEEKVLPFYSS----VLTPKEQEGIQKNNLEELTEELTK 393
K++D + + L + + E +++ V + V +Q Q + +E+ + LT+
Sbjct: 827 KLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 886
Query: 394 VMVDYIGMENFWKRYNK---VKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVL 450
V + N + K V+ E + LQ R Q +I E+L Q L S +L
Sbjct: 887 VYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEI-----EILTQKLSAKEDSIHIL 941
Query: 451 SQ 452
++
Sbjct: 942 NE 943
Score = 54.3 bits (129), Expect = 2e-07
Identities = 111/534 (20%), Positives = 208/534 (38%), Gaps = 117/534 (21%)
Query: 4 KEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINT 63
+EK + ++EK L L Q + E+ KK+ L L K +KEE AL +++ +
Sbjct: 1574 EEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVK-SKEEELKALE-DRLES 1631
Query: 64 QWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHN 123
+ L E+K + K I Q L + E EEQY SHL
Sbjct: 1632 ESAAKLAELKRKAEQKIAAIKKQ---------------LLSQMEEKEEQYKKGTESHLSE 1676
Query: 124 VDQLLALQRHRLSLLEESYN----------------MELEALTKEFETERKTIIDQ-HEK 166
++ L + + +LEE + A T++ E + + + + +E+
Sbjct: 1677 LNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEE 1736
Query: 167 EIHYLQDIFMAME----------QNYIDSEYESKLEFQSMWNDLKNMNLE--EKHFLRLH 214
+I LQ E + + S +E + ++Q L++ + E + H
Sbjct: 1737 KISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH 1796
Query: 215 LENRVEDLWRKFQDVL---------KNYTDATEDRKAAFE----TLQVKD------EKSS 255
L+ +E+ +K+ ++ KN A ++ + F+ TLQ K+ E+
Sbjct: 1797 LQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKI 1856
Query: 256 KEIE-----------VQM-------KKIQKLQDAITISKGKIMIHSRESEDENRYI---- 293
KE++ V+M +K+Q LQ +K ++ E ++
Sbjct: 1857 KELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPK 1916
Query: 294 --------RNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVD--KG 343
ND E L + K + + QK+L L E L+ L+K D +
Sbjct: 1917 LLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQERE 1976
Query: 344 EKILK------------LAEICRKFET-----EEEKVLPFYSSVLTPKEQEG-IQKNNLE 385
EKI + L ++ R+F T E+E + ++ +E E + +++ E
Sbjct: 1977 EKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE 2036
Query: 386 ELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQY 439
E + L K+ ++ KRY ++ + A++ D+ +L E+ K+Y
Sbjct: 2037 ETNQLLKKIAEKDDDLKRTAKRYEEIL--DAREEEMTAKVRDLQTQLEELQKKY 2088
Score = 51.2 bits (121), Expect = 2e-06
Identities = 84/418 (20%), Positives = 179/418 (42%), Gaps = 48/418 (11%)
Query: 71 EVKTRELHKDIEILSQTFERV---VDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQL 127
E + R+L ++ L+ +F++ ++ K+N IKS+ D+ + AL+ N Q
Sbjct: 1275 EAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTE-KEALQKEGGNQQQA 1333
Query: 128 LALQRHRLSLLEESYNMELEALT--KEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDS 185
+ + ++ L++ + + A+T KE E+K I K+ L D+ + ++ + S
Sbjct: 1334 ASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQ---LTDLNVQLQNSISLS 1390
Query: 186 EYESKLE-FQSMWNDLKNMNLEEKHFLRLHLEN----------RVEDLWRKFQDVLKNYT 234
E E+ + + +++ K L++ L ++ +V+D KF + K
Sbjct: 1391 EKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQ 1450
Query: 235 DATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIR 294
+ + LQ++ E SKE + ++I L++ + + E ED+ +
Sbjct: 1451 SRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKME 1510
Query: 295 NDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALR-----KIVDKGEKILKL 349
+ + +L+ A+ + + ++ + T+E + + L+ K ++ E + KL
Sbjct: 1511 KKESNLETELKSQTARIMEL----EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKL 1566
Query: 350 -------AEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELT------EELTKVMV 396
E + + EEK+L + V + K + +K LE + EE K +
Sbjct: 1567 QHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALE 1626
Query: 397 DYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLN 454
D + E+ K + + + + QLL ++ E +QY G ++ LS+LN
Sbjct: 1627 DRLESESAAKLAELKRKAEQKIAAIKKQLL---SQMEEKEEQYKKG---TESHLSELN 1678
Score = 37.0 bits (84), Expect = 0.040
Identities = 42/191 (21%), Positives = 90/191 (47%), Gaps = 36/191 (18%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKIN 62
+K+K+ K + +K L + +++ E E+ KK+ Q ++K+ +E+ + L K N
Sbjct: 1938 EKQKLGKEIVRLQKDLRMLRKEHQQELEILKKE---YDQEREEKIKQEQEDLEL---KHN 1991
Query: 63 TQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLH 122
+ + ++RE T+ K+ E+ ++ + +++A+E A L SH
Sbjct: 1992 STLKQLMREFNTQLAQKEQELEM---------------TIKETINKAQEVEAELLESHQE 2036
Query: 123 NVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEI-HYLQDIFMAMEQN 181
+QLL + + +L+ K +E I+D E+E+ ++D+ +E+
Sbjct: 2037 ETNQLLKKIAEK--------DDDLKRTAKRYE----EILDAREEEMTAKVRDLQTQLEE- 2083
Query: 182 YIDSEYESKLE 192
+ +Y+ KLE
Sbjct: 2084 -LQKKYQQKLE 2093
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 62.8 bits (151), Expect = 7e-10
Identities = 90/408 (22%), Positives = 182/408 (44%), Gaps = 25/408 (6%)
Query: 29 EEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQTF 88
E+ K+ ER LS+ + + KEE K+ Q ++K ++L + +E S+T
Sbjct: 452 EDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETV 511
Query: 89 ERVVDCKDNVIK---SLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNME 145
+ + + ++K L L A +Q + LR L++V ALQ L EE +
Sbjct: 512 DELTGKNNQILKEKDELKTQLYAALQQIEN-LRKELNDVLTKRALQEEELHSKEEKLR-D 569
Query: 146 LEALTKEFETERKTIID---QHEKEIHYLQDI--FMAMEQNYIDSEYESKLEFQSMWNDL 200
+++ + E E K +D + E E+ I M +E+ +++ E ++L+ +
Sbjct: 570 IKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEI-AELKKSQAQDKA 628
Query: 201 KNMNLEEK----HFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSK 256
K + ++E +R L N++ + R + VLK+ +D T K+ E +
Sbjct: 629 KLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEETATIITQLKL 688
Query: 257 EIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARA 316
E +V ++++ L ++ K K H + ++ ++ + +K +R LKA+ + +
Sbjct: 689 ERDVHQRELKDLTSSLQSVKTK---HEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKN 745
Query: 317 AS---QKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEE-EKVLPFYSSVLT 372
+ + L +L + + + L + ++ +K LKL C K + EE EK + L
Sbjct: 746 MAKIHRGQLEKLKSQCDRLTEELTQNENENKK-LKLKYQCLKDQLEEREKHISIEEEHLR 804
Query: 373 PKEQEGIQKNNLEELTEELTKVMVDYIGME--NFWKRYNKVKLEQLSL 418
E+ +Q + E + ++ IG E K ++K +E+L +
Sbjct: 805 RMEEARLQLKDQLLCLETEQESILGVIGKEIDAACKTFSKDSVEKLKV 852
Score = 39.7 bits (91), Expect = 0.006
Identities = 85/428 (19%), Positives = 160/428 (37%), Gaps = 87/428 (20%)
Query: 89 ERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRH-------------RL 135
+R ++ KD LA + + + + L +D+L +Q H ++
Sbjct: 385 KRCMERKDKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQI 444
Query: 136 SLL----------EESYNMEL---EALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNY 182
S L E Y EL EAL +E E R+ + + ++ I + ++
Sbjct: 445 SELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQWK-----LKHKK 499
Query: 183 IDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLE---NRVEDLWRKFQDVLKNYTDATED 239
++ E + E N L+EK L+ L ++E+L ++ DVL E+
Sbjct: 500 LERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEE 559
Query: 240 RKAAFETLQ-VKDEKSSKEIEV------------QMKKIQKLQDAITISKGKI------- 279
+ E L+ +K ++ E+EV ++KK K+Q + + K +
Sbjct: 560 LHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAEL 619
Query: 280 ----------MIHSRESEDENRYIRND-----------KELVLVQLRKLKAQRTQARAAS 318
++ +ES + IR D K+ VL L L AQ +
Sbjct: 620 KKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDEET 679
Query: 319 QKNLVRLTLESNATLKALRKIVDKGEKI-----LKLAEICRKFETE----EEKVLPFYSS 369
+ +L LE + + L+ + + + + E+ + F+ E E + +
Sbjct: 680 ATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAE 739
Query: 370 VLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQL--SLQHRRAQLLD 427
L K I + LE+L + ++ + EN K+ K+K + L L+ R +
Sbjct: 740 SLEEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKL-KLKYQCLKDQLEEREKHISI 798
Query: 428 INGKLREM 435
LR M
Sbjct: 799 EEEHLRRM 806
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 62.0 bits (149), Expect = 1e-09
Identities = 108/484 (22%), Positives = 212/484 (43%), Gaps = 82/484 (16%)
Query: 21 FQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKD 80
F+QK + + ++ ER+ + + ++ +S+L K ++T + KTRE+ +
Sbjct: 829 FEQKY---KMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQER 885
Query: 81 IEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEE 140
+ + Q E+ ++ +D+ ++++ ++ + E+ L+ L V + L ++ L L+E
Sbjct: 886 LNEMEQLKEQ-LENRDSTLQTVEREKTLITEK----LQQTLEEV-KTLTQEKDDLKQLQE 939
Query: 141 SYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDL 200
S +E + L + ID E+ + + ES + Q N L
Sbjct: 940 SLQIERDQLKSDIHDTVNMNIDTQEQ----------------LRNALESLKQHQETINTL 983
Query: 201 KNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEV 260
K+ + E+ LH+E + +FQ + D +D +A D K ++ IE
Sbjct: 984 KS-KISEEVSRNLHMEENTGETKDEFQQKMVG-IDKKQDLEAKNTQTLTADVKDNEIIEQ 1041
Query: 261 QMK---------KIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQR 311
Q K ++Q++ +++ K ++ +E+ + I N +EL L+ +LK Q
Sbjct: 1042 QRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMT--IENQEELRLLG-DELKKQ- 1097
Query: 312 TQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVL 371
Q A +KN A++K +GE L+ C + EEK L S L
Sbjct: 1098 -QEIVAQEKN------------HAIKK---EGE----LSRTCDRLAEVEEK-LKEKSQQL 1136
Query: 372 TPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGK 431
K+Q+ L + EE++++ +EN N++K ++L+L+H + L++ K
Sbjct: 1137 QEKQQQ------LLNVQEEMSEMQKKINEIENL---KNELKNKELTLEHMETERLELAQK 1187
Query: 432 LREMLKQYLDGISVSDEVLSQLNPLF----------IVNYQSNLLQPL-SIRIAHPGDKQ 480
L E ++ + I+ +VL +L F I ++ LQ ++IAH K+
Sbjct: 1188 LNENYEE-VKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKE 1246
Query: 481 HPTT 484
H T
Sbjct: 1247 HQET 1250
Score = 60.8 bits (146), Expect = 3e-09
Identities = 111/473 (23%), Positives = 215/473 (45%), Gaps = 76/473 (16%)
Query: 9 KTPLSDEKQLLLFQQKLLAEEEMAKKKERL-----LSQFLKDKLAKEEHNSALNLN---K 60
K+ EKQ QQ L +EEM++ ++++ L LK+K EH L K
Sbjct: 1132 KSQQLQEKQ----QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQK 1187
Query: 61 INTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSL-AKDLSEAEE-QYAHA-L 117
+N + V K R++ K+++ ++FE D I+ + A L EE + AH L
Sbjct: 1188 LNENYEEVKSITKERKVLKELQ---KSFETERDHLRGYIREIEATGLQTKEELKIAHIHL 1244
Query: 118 RSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMA 177
+ H +D+L + + + + ++E + T + + +H Q++
Sbjct: 1245 KEHQETIDELRRSVSEKTAQIINTQDLE----------KSHTKLQEEIPVLHEEQELLPN 1294
Query: 178 MEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLEN-RVEDLWRKFQDVLKNYTDA 236
+++ E ++LE + + K+ R+ +E R+ + +++ Q+ +K+ T
Sbjct: 1295 VKEVSETQETMNELELLTEQSTTKDSTT----LARIEMERLRLNEKFQESQEEIKSLTKE 1350
Query: 237 TEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRND 296
++ K E L+VK ++ + I + KIQ+ Q SK + ++ +E ++E I ++
Sbjct: 1351 RDNLKTIKEALEVKHDQLKEHIRETLAKIQESQ-----SKQEQSLNMKEKDNETTKIVSE 1405
Query: 297 KE--------LVLVQLRKL-KAQRTQARAASQKNLVR-----------LTLESNATLKAL 336
E L+ +++ L ++R Q K++ + L ES+ + +
Sbjct: 1406 MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI 1465
Query: 337 RKIVDK---GEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQE--GIQKNNLEELTEEL 391
++IV K E+ LK+A C K E+E+ + L+ KE E IQK LE + ++L
Sbjct: 1466 KEIVAKHLETEEELKVAHCCLK---EQEETINELRVNLSEKETEISTIQK-QLEAINDKL 1521
Query: 392 -TKVMVDYIGMENF-WKRYNKV--KLEQLS--LQHRRAQ---LLDINGKLREM 435
K+ Y E F K+ ++V K+ +L +HR+A+ L I K+ E+
Sbjct: 1522 QNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLEL 1574
Score = 53.1 bits (126), Expect = 5e-07
Identities = 92/445 (20%), Positives = 188/445 (42%), Gaps = 62/445 (13%)
Query: 43 LKDKLAKE-EHNSALN--------LNKINTQWRTVLREV--KTRELHKDIEILSQTFERV 91
L+ +L KE E N AL L + ++ + +E+ K+ ELH + F V
Sbjct: 725 LQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEV 784
Query: 92 VDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTK 151
V K++ ++ L +++ + ++ A +S+ + DQ + E+ Y M LE
Sbjct: 785 VH-KESRVQGLLEEIGKTKDDLA-TTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLE---- 838
Query: 152 EFETERKTIIDQHEKEIHYLQDI-FMAMEQNYIDSEYESKL-EFQSMWNDLKNMN--LEE 207
E E + I++ ++ + + + E +Y E + K E Q N+++ + LE
Sbjct: 839 ENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLEN 898
Query: 208 KHFLRLHLENRVEDLWRKFQDVL---KNYTDATEDRKAAFETLQVKDEK----------- 253
+ +E + K Q L K T +D K E+LQ++ ++
Sbjct: 899 RDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNM 958
Query: 254 ---SSKEIEVQMKKIQKLQDAITISKGKIM------IHSRESEDENRYIRNDKELVLVQL 304
+ +++ ++ +++ Q+ I K KI +H E+ E + K + + +
Sbjct: 959 NIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKK 1018
Query: 305 RKLKAQRTQARAAS---------QKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRK 355
+ L+A+ TQ A Q+ + L E N + L ++ + E++ + +
Sbjct: 1019 QDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIE 1078
Query: 356 FETEEEKVLPFYSSVLTPKEQEGI--QKNNLEELTEELTKVMVDYIGMENFWKRYNKVKL 413
E ++ L L K+QE + +KN+ + EL++ +E K+K
Sbjct: 1079 MTIENQEELRLLGDELK-KQQEIVAQEKNHAIKKEGELSRTCDRLAEVEE------KLKE 1131
Query: 414 EQLSLQHRRAQLLDINGKLREMLKQ 438
+ LQ ++ QLL++ ++ EM K+
Sbjct: 1132 KSQQLQEKQQQLLNVQEEMSEMQKK 1156
Score = 45.4 bits (106), Expect = 1e-04
Identities = 90/431 (20%), Positives = 187/431 (43%), Gaps = 71/431 (16%)
Query: 9 KTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTV 68
KT ++++ Q L + K L +E+ K+ + Q +D+L + H++ +N+N I+TQ
Sbjct: 910 KTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDT-VNMN-IDTQ---- 963
Query: 69 LREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAE------------------ 110
+L +E L Q E + K + + ++++L E
Sbjct: 964 ------EQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDK 1017
Query: 111 EQYAHALRSHLHNVD----QLLALQRHRLSLLEESYNME--LEALTKEFE---TERKTII 161
+Q A + D +++ QR SL++E ++ LE++ E E T+ K I
Sbjct: 1018 KQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENI 1077
Query: 162 D---QHEKEIHYLQDIFMAMEQNYI-DSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLEN 217
+ ++++E+ L D ++ + + K E + + +EEK L+
Sbjct: 1078 EMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEK------LKE 1131
Query: 218 RVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKG 277
+ + L K Q +L + +E +K E +K+E +KE+ ++ + ++L+ A +++
Sbjct: 1132 KSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNEN 1191
Query: 278 KIMIHSRESE-----DENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNAT 332
+ S E + + +++ + +R+++A Q + + + L E T
Sbjct: 1192 YEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLK-EHQET 1250
Query: 333 LKALRKIV-DKGEKILKLAEICRKFET----------EEEKVLPFYSSVLTPKEQEGIQK 381
+ LR+ V +K +I+ ++ K T EE+++LP V +E
Sbjct: 1251 IDELRRSVSEKTAQIINTQDL-EKSHTKLQEEIPVLHEEQELLPNVKEVSETQE----TM 1305
Query: 382 NNLEELTEELT 392
N LE LTE+ T
Sbjct: 1306 NELELLTEQST 1316
Score = 44.3 bits (103), Expect = 3e-04
Identities = 105/493 (21%), Positives = 208/493 (42%), Gaps = 80/493 (16%)
Query: 28 EEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELH-KDIEILSQ 86
EE + KER + +++ L E NL + T+ E+K +H K+ +
Sbjct: 1679 EEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETID 1738
Query: 87 TFERVVDCKDNVIKSLAKDLSEAEE-------------QYAHA-LRSHLHNVDQLLALQR 132
+V K N I ++ KDL + + + AH L+ +D+L +
Sbjct: 1739 KLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVS 1798
Query: 133 HRLSLLE------ESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSE 186
+ L E+ N +L+ +E + +I +K+++ Q MEQ +
Sbjct: 1799 EKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITL-KKDVNETQKKVSEMEQLKKQIK 1857
Query: 187 YES----KLEFQSMWNDLK-NMNLEEKHFLRLHLEN--RVEDLWRKFQDVLKNYTDATED 239
+S KLE +++ K + NLEE + +N RVE+ + +D LK
Sbjct: 1858 DQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLK-------- 1909
Query: 240 RKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKEL 299
E+LQ E ++++E+Q Q+L+ A +SK +E+ D+ R ++K
Sbjct: 1910 -----ESLQ---ETKARDLEIQ----QELKTARMLSK-----EHKETVDKLREKISEK-- 1950
Query: 300 VLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETE 359
+Q+ ++ +++ QK + L + L+ + +KI ++ ++ ++FE +
Sbjct: 1951 -TIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQ 2009
Query: 360 EEKV--LPFYSSVLTPKEQEGI--------QKNNLEELTEELTKVMVDYIG----MENFW 405
+ + + LT K E + +++ L + E L +I M
Sbjct: 2010 NLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARD 2069
Query: 406 KRYNKVKLEQLSL----QHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFI-VN 460
++ ++VK E+ L QH L + +++E+LK+Y S D+ LN L + +
Sbjct: 2070 RQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRY----SEMDDHYECLNRLSLDLE 2125
Query: 461 YQSNLLQPLSIRI 473
+ + LS+R+
Sbjct: 2126 KEIEFQKELSMRV 2138
Score = 35.8 bits (81), Expect = 0.089
Identities = 79/408 (19%), Positives = 164/408 (40%), Gaps = 45/408 (11%)
Query: 5 EKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQ 64
+K+ + + ++L+ L ++E+ K++R ++ L K+ K ++++ + I T
Sbjct: 387 QKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCL-GKINKMKNSNYADQFNIPTN 445
Query: 65 WRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNV 124
T KT +L I +L + E V D V + LSE E A L + +
Sbjct: 446 ITT-----KTHKL--SINLLREIDESVCSESD-VFSNTLDTLSEIEWNPATKLLNQENIE 497
Query: 125 DQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAME-QNYI 183
+L +L+ +L+ + + E E + + K +D+ F A+E +
Sbjct: 498 SELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDE-----------FEALERKTKK 546
Query: 184 DSEYESKLEFQSMWNDLK-----NMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATE 238
D E + E ++ N +K N +LE + ++ L ED +K Q+ + +
Sbjct: 547 DQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENI 606
Query: 239 DRKAAFETLQVKDEKSSKE--IEVQMKKIQKLQDAITISKGKIMIHSRESEDENRY--IR 294
++ ++D K K+ + + + +++ + + + + E Y +
Sbjct: 607 KMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQME 666
Query: 295 NDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESN-----------ATLKALRKIVDKG 343
ND +L QL K + Q +T ++ L+ KI D
Sbjct: 667 NDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQ 726
Query: 344 EKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEEL 391
+++ K E + E E+V+ P E E ++K +++ +EEL
Sbjct: 727 KELNKEVE---ENEALREEVILLSELKSLPSEVERLRK-EIQDKSEEL 770
Score = 32.3 bits (72), Expect = 0.99
Identities = 84/410 (20%), Positives = 156/410 (38%), Gaps = 62/410 (15%)
Query: 15 EKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKT 74
EK+LL Q+ L E ++K + + LK ++H LN +
Sbjct: 2078 EKRLLSDGQQHLTES--LREKCSRIKELLKRYSEMDDHYECLNRLSL------------- 2122
Query: 75 RELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHR 134
+L K+IE + RV +LS Q H + L +Q +++ HR
Sbjct: 2123 -DLEKEIEFQKELSMRV-----------KANLSLPYLQTKHIEK--LFTANQRCSMEFHR 2168
Query: 135 LSLLEESYNMELEALTKEFETERKTI-------IDQHEKEIHYLQDIFMAMEQNYIDSEY 187
+ + L +TK E + ++I ID+ EK+ L I + + S
Sbjct: 2169 IM---KKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRE 2225
Query: 188 ESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETL 247
L+ +NM+L + L+ E+ + +FQ VL N + T+ + T
Sbjct: 2226 LRDLKLN------QNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNT- 2278
Query: 248 QVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRK- 306
+ EK I+ + +I ++ + IM S E E+ + I + E L L++
Sbjct: 2279 RFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEK 2338
Query: 307 ----LKAQRTQARAASQKNLVRLTLESN--------ATLKALRKIVDKGEKILKLAEICR 354
K +T + + V T + N AT KI + + + E
Sbjct: 2339 NEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAM 2398
Query: 355 KFET---EEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGM 401
E+ + +K L + ++ + + + N E T+E +V+ D + +
Sbjct: 2399 HKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVAL 2448
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 61.6 bits (148), Expect = 2e-09
Identities = 94/452 (20%), Positives = 195/452 (43%), Gaps = 61/452 (13%)
Query: 4 KEKMAKTPLS----DEKQLLLFQQK------LLAEEEMAKKKERLLSQFLKDKLA----- 48
K+++AK+ +EK + L ++K + AE E E Q +K K+
Sbjct: 866 KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKI 925
Query: 49 KEEHNSALNLNKINTQWRTVLREVKTR--ELHKDIEILSQTFERVVDCK---DNVIKSLA 103
KE A + +IN + R+++ EL KDI+ L T +V K +N +K+L
Sbjct: 926 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 985
Query: 104 KDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQ 163
++++ +D+ +A L+E++ L+ L E E + T+
Sbjct: 986 EEMA---------------GLDETIAKLTKEKKALQEAHQQTLDDLQAE-EDKVNTLTKA 1029
Query: 164 HEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLK-NMNLEEKHFLRLHLENR-VED 221
K + D+ ++EQ E + +++ + L+ ++ L ++ + + E + +++
Sbjct: 1030 KIKLEQQVDDLEGSLEQ-----EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084
Query: 222 LWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMI 281
+K + + N ED +A L ++ +K KE++ +++++++ +A S+ K
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQA----LGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 282 H----SRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALR 337
SRE E+ + + Q+ K + + + +++L TL+ AT LR
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM-RRDLEEATLQHEATAATLR 1199
Query: 338 K-----IVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELT 392
K + + GE+I L + +K E E+ ++ + + E K NLE++ L
Sbjct: 1200 KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE 1259
Query: 393 KVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQ 424
+ + E +R + L+ Q R Q
Sbjct: 1260 DQLSELKSKEEEQQRL----INDLTAQRGRLQ 1287
Score = 39.3 bits (90), Expect = 0.008
Identities = 114/556 (20%), Positives = 207/556 (37%), Gaps = 113/556 (20%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKIN 62
++EK + L K+ L KL E M + E+ Q L +KL K+E + +KI
Sbjct: 1045 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEK---QQLDEKLKKKEFEISNLQSKIE 1101
Query: 63 TQWRTVLR-EVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHL 121
+ ++ + K +EL IE L + E + K + DLS E+ + L
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAG 1160
Query: 122 HNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQ---DIFMAM 178
+ + + R + ++ +LE T + E T+ +H + L D +
Sbjct: 1161 GATSAQIEMNKKREAEFQKM-RRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1219
Query: 179 EQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRL--HLENRVEDLWRKFQDVLKNYTDA 236
+Q + E K+E + ++++ ++ + + ++ LE+++ +L K ++ + D
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDL 1279
Query: 237 TEDR---------------------------KAAFETLQVKDEKSSKEIEVQMKKI---- 265
T R K AF T Q+++ K E E++ K
Sbjct: 1280 TAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAF-TQQIEELKRQLEEEIKAKNALAHA 1338
Query: 266 --------------------QKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLR 305
K + +SK + ++ E I+ +EL + +
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE--EAK 1396
Query: 306 KLKAQRTQAR-----------AASQKNLVRLTLE----------SNATLKALRKIVDKGE 344
K AQR QA A+ +K RL E +NA AL K +
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
Query: 345 KILKL---------AEI------CRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTE 389
KIL AE+ R TE K+ Y L E + NL++
Sbjct: 1457 KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1516
Query: 390 ELTKVMVD----YIGMENFWKRYNKVKLE--------QLSLQHRRAQLLDINGKLREMLK 437
+LT+ + + +E K+ + K E + SL+H ++L I +L ++
Sbjct: 1517 DLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKS 1576
Query: 438 QYLDGISVSDEVLSQL 453
+ I+ DE + QL
Sbjct: 1577 EVDRKIAEKDEEIDQL 1592
Score = 37.7 bits (86), Expect = 0.024
Identities = 60/321 (18%), Positives = 130/321 (40%), Gaps = 47/321 (14%)
Query: 29 EEMAKKKERLLSQFLKDKLAKEEHNSALN-----LNKINTQWRTVLREVKTRELHKDIEI 83
EEMA E + + K +E H L+ +K+NT + ++K + D+E
Sbjct: 986 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKA---KIKLEQQVDDLEG 1042
Query: 84 LSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLL----- 138
+ +++ + + L DL A+E + + +D+ L + +S L
Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMD-IENEKQQLDEKLKKKEFEISNLQSKIE 1101
Query: 139 -EESYNMELEALTKEFETERKTIIDQHEKE--------------IHYLQDIFMAMEQN-- 181
E++ ++L+ KE + + + ++ E E L++I +E+
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1161
Query: 182 ----YIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDAT 237
I+ + + EFQ M DL+ L+ E L +K D + +
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQH--------EATAATLRKKHADSVAELGEQI 1213
Query: 238 EDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDK 297
++ + ++ K EK E+++++ + + ++ +KG + R ED+ +++ +
Sbjct: 1214 DN----LQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKE 1269
Query: 298 ELVLVQLRKLKAQRTQARAAS 318
E + L AQR + + S
Sbjct: 1270 EEQQRLINDLTAQRGRLQTES 1290
Score = 31.6 bits (70), Expect = 1.7
Identities = 43/205 (20%), Positives = 82/205 (40%), Gaps = 24/205 (11%)
Query: 249 VKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLK 308
+K ++ KE+ ++ QK++D + S+ K R + E +V L K K
Sbjct: 846 LKSAETEKEMATMKEEFQKIKDELAKSEAK---------------RKELEEKMVTLLKEK 890
Query: 309 AQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYS 368
A + L ++A + + I K + K+ E+ + E EEE +
Sbjct: 891 NDLQLQVQAEAEGL------ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTA 944
Query: 369 SVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDI 428
+++ K ++++L L KV + EN K + E L A+L
Sbjct: 945 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE---EMAGLDETIAKLTKE 1001
Query: 429 NGKLREMLKQYLDGISVSDEVLSQL 453
L+E +Q LD + ++ ++ L
Sbjct: 1002 KKALQEAHQQTLDDLQAEEDKVNTL 1026
Score = 29.6 bits (65), Expect = 6.4
Identities = 53/273 (19%), Positives = 102/273 (37%), Gaps = 42/273 (15%)
Query: 23 QKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIE 82
++L A E ++ ++ Q L D + + N + INT+ ++L DI
Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK----------KKLETDIS 1741
Query: 83 ILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESY 142
+ E ++ ++ AEE+ A+ ++L Q L
Sbjct: 1742 QMQGEMEDIL-----------QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1790
Query: 143 NME--LEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDL 200
NME ++ L + + + +K+I L+ +E ++SE + E +
Sbjct: 1791 NMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGE-VESEQKRNAEA------V 1843
Query: 201 KNMNLEEKHFLRLHLEN--------RVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDE 252
K + E+ L + R++DL K Q +K+Y E+ + T K
Sbjct: 1844 KGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFR 1903
Query: 253 KSSKEIEVQMKKIQKLQDAITISKGKIMIHSRE 285
K E+E + ++ D K+ + SRE
Sbjct: 1904 KLQHELE----EAEERADIAESQVNKLRVKSRE 1932
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 61.6 bits (148), Expect = 2e-09
Identities = 94/452 (20%), Positives = 195/452 (43%), Gaps = 61/452 (13%)
Query: 4 KEKMAKTPLS----DEKQLLLFQQK------LLAEEEMAKKKERLLSQFLKDKLA----- 48
K+++AK+ +EK + L ++K + AE E E Q +K K+
Sbjct: 866 KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKI 925
Query: 49 KEEHNSALNLNKINTQWRTVLREVKTR--ELHKDIEILSQTFERVVDCK---DNVIKSLA 103
KE A + +IN + R+++ EL KDI+ L T +V K +N +K+L
Sbjct: 926 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 985
Query: 104 KDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQ 163
++++ +D+ +A L+E++ L+ L E E + T+
Sbjct: 986 EEMA---------------GLDETIAKLTKEKKALQEAHQQTLDDLQAE-EDKVNTLTKA 1029
Query: 164 HEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLK-NMNLEEKHFLRLHLENR-VED 221
K + D+ ++EQ E + +++ + L+ ++ L ++ + + E + +++
Sbjct: 1030 KIKLEQQVDDLEGSLEQ-----EKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084
Query: 222 LWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMI 281
+K + + N ED +A L ++ +K KE++ +++++++ +A S+ K
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQA----LGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 282 H----SRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALR 337
SRE E+ + + Q+ K + + + +++L TL+ AT LR
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM-RRDLEEATLQHEATAATLR 1199
Query: 338 K-----IVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELT 392
K + + GE+I L + +K E E+ ++ + + E K NLE++ L
Sbjct: 1200 KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLE 1259
Query: 393 KVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQ 424
+ + E +R + L+ Q R Q
Sbjct: 1260 DQLSELKSKEEEQQRL----INDLTAQRGRLQ 1287
Score = 39.3 bits (90), Expect = 0.008
Identities = 114/556 (20%), Positives = 207/556 (37%), Gaps = 113/556 (20%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKIN 62
++EK + L K+ L KL E M + E+ Q L +KL K+E + +KI
Sbjct: 1045 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEK---QQLDEKLKKKEFEISNLQSKIE 1101
Query: 63 TQWRTVLR-EVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHL 121
+ ++ + K +EL IE L + E + K + DLS E+ + L
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSRELEEISERLEEAG 1160
Query: 122 HNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQ---DIFMAM 178
+ + + R + ++ +LE T + E T+ +H + L D +
Sbjct: 1161 GATSAQIEMNKKREAEFQKM-RRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRV 1219
Query: 179 EQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRL--HLENRVEDLWRKFQDVLKNYTDA 236
+Q + E K+E + ++++ ++ + + ++ LE+++ +L K ++ + D
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDL 1279
Query: 237 TEDR---------------------------KAAFETLQVKDEKSSKEIEVQMKKI---- 265
T R K AF T Q+++ K E E++ K
Sbjct: 1280 TAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAF-TQQIEELKRQLEEEIKAKNALAHA 1338
Query: 266 --------------------QKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLR 305
K + +SK + ++ E I+ +EL + +
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE--EAK 1396
Query: 306 KLKAQRTQAR-----------AASQKNLVRLTLE----------SNATLKALRKIVDKGE 344
K AQR QA A+ +K RL E +NA AL K +
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
Query: 345 KILKL---------AEI------CRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTE 389
KIL AE+ R TE K+ Y L E + NL++
Sbjct: 1457 KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1516
Query: 390 ELTKVMVD----YIGMENFWKRYNKVKLE--------QLSLQHRRAQLLDINGKLREMLK 437
+LT+ + + +E K+ + K E + SL+H ++L I +L ++
Sbjct: 1517 DLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKS 1576
Query: 438 QYLDGISVSDEVLSQL 453
+ I+ DE + QL
Sbjct: 1577 EVDRKIAEKDEEIDQL 1592
Score = 37.7 bits (86), Expect = 0.024
Identities = 60/321 (18%), Positives = 130/321 (40%), Gaps = 47/321 (14%)
Query: 29 EEMAKKKERLLSQFLKDKLAKEEHNSALN-----LNKINTQWRTVLREVKTRELHKDIEI 83
EEMA E + + K +E H L+ +K+NT + ++K + D+E
Sbjct: 986 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKA---KIKLEQQVDDLEG 1042
Query: 84 LSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLL----- 138
+ +++ + + L DL A+E + + +D+ L + +S L
Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMD-IENEKQQLDEKLKKKEFEISNLQSKIE 1101
Query: 139 -EESYNMELEALTKEFETERKTIIDQHEKE--------------IHYLQDIFMAMEQN-- 181
E++ ++L+ KE + + + ++ E E L++I +E+
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1161
Query: 182 ----YIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDAT 237
I+ + + EFQ M DL+ L+ E L +K D + +
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQH--------EATAATLRKKHADSVAELGEQI 1213
Query: 238 EDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDK 297
++ + ++ K EK E+++++ + + ++ +KG + R ED+ +++ +
Sbjct: 1214 DN----LQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKE 1269
Query: 298 ELVLVQLRKLKAQRTQARAAS 318
E + L AQR + + S
Sbjct: 1270 EEQQRLINDLTAQRGRLQTES 1290
Score = 31.6 bits (70), Expect = 1.7
Identities = 43/205 (20%), Positives = 82/205 (40%), Gaps = 24/205 (11%)
Query: 249 VKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLK 308
+K ++ KE+ ++ QK++D + S+ K R + E +V L K K
Sbjct: 846 LKSAETEKEMATMKEEFQKIKDELAKSEAK---------------RKELEEKMVTLLKEK 890
Query: 309 AQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYS 368
A + L ++A + + I K + K+ E+ + E EEE +
Sbjct: 891 NDLQLQVQAEAEGL------ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTA 944
Query: 369 SVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDI 428
+++ K ++++L L KV + EN K + E L A+L
Sbjct: 945 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE---EMAGLDETIAKLTKE 1001
Query: 429 NGKLREMLKQYLDGISVSDEVLSQL 453
L+E +Q LD + ++ ++ L
Sbjct: 1002 KKALQEAHQQTLDDLQAEEDKVNTL 1026
Score = 29.6 bits (65), Expect = 6.4
Identities = 53/273 (19%), Positives = 102/273 (37%), Gaps = 42/273 (15%)
Query: 23 QKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIE 82
++L A E ++ ++ Q L D + + N + INT+ ++L DI
Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK----------KKLETDIS 1741
Query: 83 ILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESY 142
+ E ++ ++ AEE+ A+ ++L Q L
Sbjct: 1742 QMQGEMEDIL-----------QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1790
Query: 143 NME--LEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDL 200
NME ++ L + + + +K+I L+ +E ++SE + E +
Sbjct: 1791 NMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGE-VESEQKRNAEA------V 1843
Query: 201 KNMNLEEKHFLRLHLEN--------RVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDE 252
K + E+ L + R++DL K Q +K+Y E+ + T K
Sbjct: 1844 KGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFR 1903
Query: 253 KSSKEIEVQMKKIQKLQDAITISKGKIMIHSRE 285
K E+E + ++ D K+ + SRE
Sbjct: 1904 KLQHELE----EAEERADIAESQVNKLRVKSRE 1932
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 61.2 bits (147), Expect = 2e-09
Identities = 98/481 (20%), Positives = 205/481 (42%), Gaps = 40/481 (8%)
Query: 4 KEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINT 63
+E A+ E++ LL +QK + E +++LL + +KL KE+ K+
Sbjct: 1960 QELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQE--TEKLMKEKLEVQCQAEKVRD 2017
Query: 64 QWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHN 123
+ ++VK E+ D+E F + K+ + L + ++A E+ +R L
Sbjct: 2018 DLQ---KQVKALEI--DVEEQVSRFIELEQEKNTELMDLRQQ-NQALEKQLEKMRKFLD- 2070
Query: 124 VDQLLALQRHRLSLLEESYNMELEALT-------KEFETERKTIIDQHEKE-IHYLQDIF 175
+Q + + R +E +E + E +T + H KE ++
Sbjct: 2071 -EQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELL 2129
Query: 176 MAMEQNYID----SEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLK 231
++ EQ D +E KLEF+ + + + KHF + + + + L+
Sbjct: 2130 LSKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELS-----LEVQLQ 2184
Query: 232 NYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENR 291
DA + ++ L+ + E+ +E+E + +++Q+L + I K + +E E EN+
Sbjct: 2185 AERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENK 2244
Query: 292 YIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAE 351
++D E + + +++ A TQ + ++ E + L + V K ++ LK+
Sbjct: 2245 LFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITT 2304
Query: 352 ICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVM------VDYIGMENFW 405
+ E + E + + + + K N EE E+L +V+ + IG +
Sbjct: 2305 DNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSM 2364
Query: 406 KRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNL 465
++ + E SL+H+ LD+ + L+Q ++ + ++E+ N L N++ N
Sbjct: 2365 NAHS-LSEEADSLKHQ----LDVVIAEKLALEQQVE--TANEEMTFMKNVLKETNFKMNQ 2417
Query: 466 L 466
L
Sbjct: 2418 L 2418
Score = 30.8 bits (68), Expect = 2.9
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 108 EAEEQYAHALRSHLHNVD-----QLLALQRHRLSLLEESYNMELEALTKEFETERKTIID 162
E E H+ ++L ++D +L +LQ + LEE ELE+L + + K
Sbjct: 1301 ETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQ-ELESLISSLQQQLKETEQ 1359
Query: 163 QHEKEIHYLQDIFMAMEQNYI 183
+E EIH LQ A+ ++ +
Sbjct: 1360 NYEAEIHCLQKRLQAVSESTV 1380
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 61.2 bits (147), Expect = 2e-09
Identities = 100/489 (20%), Positives = 218/489 (44%), Gaps = 54/489 (11%)
Query: 27 AEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQ 86
A EM ++K L Q ++ + + ++ + LNK+ +++ + + T + K++E Q
Sbjct: 362 AVAEMEQEKFDLQKQHTEN-IQELLEDTNVRLNKMESEY--MAQTQSTNHMIKELEARVQ 418
Query: 87 TFERVVDCKDNVIKSLAKDLSEAEEQY---------AHALRSHLHNV-DQLLALQRHRLS 136
+ + + L ++ +E E Y A R+ LH D L+ +
Sbjct: 419 QLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMK 478
Query: 137 LLEESYNMELEALTKEFE---TERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEF 193
LL+ Y+ ++ L +E ++ ++I++ E+ + L+ E + + +F
Sbjct: 479 LLQTKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKF 538
Query: 194 QSMWNDLKNMNLEEKHFLRLHLENRVEDLWRK---FQDVLKN----YTDATEDRK----- 241
Q + LK++ ++ H L+ L+ ED +K F++ LK T TE ++
Sbjct: 539 QMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQ 598
Query: 242 --AAFETLQVKDEKSSKEIEVQMKK-IQKLQDAITISKGKIMIHSRESEDENRYIRNDKE 298
AA E + + E +S+++ +MK+ ++K++ +T SK S+E + IR E
Sbjct: 599 ADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYE 658
Query: 299 LVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEI-----C 353
+V+L KL+ ++ + Q N E ++ ++ + ++ EK L+ A +
Sbjct: 659 QQIVEL-KLEHEQEKTHLLQQHNA-----EKDSLVRDHEREIENLEKQLRAANMEHENQI 712
Query: 354 RKFETEEEKVLPFYSSVLTPKEQEGI-----QKNNLEEL----TEELTKVMVDYIGMENF 404
++F+ + +V+ + + +E I +K L EL EE + ++ + N
Sbjct: 713 QEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNK 772
Query: 405 WKRYN---KVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNY 461
K + K++L++ L N KL+++ K+Y ++ S +++++L
Sbjct: 773 LKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLK 832
Query: 462 QSNLLQPLS 470
+ N Q L+
Sbjct: 833 EENSQQQLA 841
Score = 57.4 bits (137), Expect = 3e-08
Identities = 106/520 (20%), Positives = 222/520 (42%), Gaps = 56/520 (10%)
Query: 4 KEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINT 63
K KM + +EK L QQK A+ + +++ + LK ++H + + K+
Sbjct: 260 KTKMMEAKFHEEK--LKLQQKHDADVQKILERKNNEIEELKTLYRSKQHETEETIRKLEK 317
Query: 64 QWRTVLREVKT-RELHKD-IEILSQTFERVVDCKDN-VIKSLAKDLSEAEEQYAHALRSH 120
+ +T++R+ + RE +D I L + E+ + +N K L ++E E++ + H
Sbjct: 318 KVQTLIRDCQVIRETKEDQIAELKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQH 377
Query: 121 LHNVDQLLALQRHRLSLLEESYN----------MELEA----LTKEFET----ERKTIID 162
N+ +LL RL+ +E Y ELEA LT E E +K I +
Sbjct: 378 TENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQE 437
Query: 163 QHEKEIHY------LQDI-----FMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFL 211
+ E E Y LQ++ + E++++ ++YE ++ D L+++H L
Sbjct: 438 KAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHAL 497
Query: 212 RL-HLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIE------VQMKK 264
+ +E+L + + + ++ RK Q++D+++ ++E + KK
Sbjct: 498 SASKASSMIEELEQNVCQLKQQLQESELQRKQ-----QLRDQENKFQMEKSHLKHIYEKK 552
Query: 265 IQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLV-QLRKLKAQRTQARAASQKNLV 323
LQ + KGK + + E +++L V ++++L+AQ+ A K V
Sbjct: 553 AHDLQS--ELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQV 610
Query: 324 RLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNN 383
L E K ++ ++ EK+ + ++ K + + + ++ I +
Sbjct: 611 ELNSE-----KVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELK 665
Query: 384 LEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGI 443
LE +E T ++ + ++ R ++ ++E L Q R A ++ +++E K+ I
Sbjct: 666 LEH-EQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAAN-MEHENQIQEFKKRDAQVI 723
Query: 444 SVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAHPGDKQHPT 483
+ + + +L I Q + + + +KQ T
Sbjct: 724 ADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRAT 763
Score = 48.5 bits (114), Expect = 1e-05
Identities = 70/287 (24%), Positives = 120/287 (41%), Gaps = 49/287 (17%)
Query: 35 KERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLR--EVKTRELHKDIEILSQTFERVV 92
++R Q ++ KL E+ + L L + N + +++R E + L K + + E +
Sbjct: 654 RQRYEQQIVELKLEHEQEKTHL-LQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQI 712
Query: 93 DCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKE 152
K A+ +++ E Q H LR L NV+ Q L LL E E + T+E
Sbjct: 713 Q---EFKKRDAQVIADMEAQ-VHKLREELINVNSQRKQQLVELGLLREE---EKQRATRE 765
Query: 153 FETERKTIIDQHEK-----EIHYLQDIFMAMEQ-----NYIDSEYESKL--------EFQ 194
E + + EK + + + M +E+ I+ EY KL E Q
Sbjct: 766 HEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQ 825
Query: 195 SMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKS 254
+ + LK N +++ L E R++D+ +KF+D K D A + LQ + E
Sbjct: 826 TTISSLKEENSQQQ----LAAERRLQDVRQKFEDEKKQLI---RDNDQAIKVLQDELENR 878
Query: 255 SKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVL 301
S ++ KK+Q + ES+++ YIR + E L
Sbjct: 879 SNQVRCAEKKLQHKE--------------LESQEQITYIRQEYETKL 911
Score = 31.2 bits (69), Expect = 2.2
Identities = 41/201 (20%), Positives = 81/201 (40%), Gaps = 48/201 (23%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLRE 71
++ +++ L + LL EEE K++ + + +KL E + L K + E
Sbjct: 740 VNSQRKQQLVELGLLREEE--KQRATREHEIVVNKLKAESEKMKIELKKTHA----AETE 793
Query: 72 VKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQ 131
+ + + ++ + + + + + +I L +S +E+ N Q LA +
Sbjct: 794 MTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEE----------NSQQQLAAE 843
Query: 132 RHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQD------------------ 173
R L+ + ++FE E+K +I +++ I LQD
Sbjct: 844 RR------------LQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQH 891
Query: 174 -IFMAMEQ-NYIDSEYESKLE 192
+ EQ YI EYE+KL+
Sbjct: 892 KELESQEQITYIRQEYETKLK 912
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 59.3 bits (142), Expect = 8e-09
Identities = 102/497 (20%), Positives = 212/497 (42%), Gaps = 94/497 (18%)
Query: 4 KEKMAKTPLS----DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLN 59
KE++A++ +EK + L Q+K + ++ + E L+ EE L +
Sbjct: 864 KEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDA--------EERCEGLIKS 915
Query: 60 KINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNV---IKSLAKDLSEAE------ 110
KI L E K +EL + +E + +V K N+ SL +D+ + E
Sbjct: 916 KI-------LLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKV 968
Query: 111 EQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHY 170
E+ HA + + N+ + ++ LEE+ + LTKE +K++ + H++ +
Sbjct: 969 EKEKHATENKVKNLSE-------EMTALEEN----ISKLTKE----KKSLQEAHQQTLDD 1013
Query: 171 LQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVL 230
LQ +E++ ++ + + + +DL+ +LE++ LR LE L +
Sbjct: 1014 LQ-----VEEDKVNGLIKINAKLEQQTDDLEG-SLEQEKKLRADLERAKRKLEGDLKMSQ 1067
Query: 231 KNYTDATEDRKAAFETLQVKD-EKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDE 289
++ D D++ E L+ K+ E S + ++ +++ LQ I + + I E E E
Sbjct: 1068 ESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIE 1127
Query: 290 NRY-----IRNDKELVLVQLRKLKAQRTQARAAS-----------------QKNLVRLTL 327
+ I + + +L ++ + +A A+ +++L TL
Sbjct: 1128 AEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATL 1187
Query: 328 ESNATLKALRK-----IVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKN 382
+ AT LRK + + GE+I L + +K E E+ ++ K + +
Sbjct: 1188 QHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSEL----------KMEIDDMAS 1237
Query: 383 NLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQH----RRAQLLDINGKLREMLKQ 438
N+E L++ + + +E+ + +Q L H ++A+L NG+L +++
Sbjct: 1238 NIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297
Query: 439 ---YLDGISVSDEVLSQ 452
+ ++ S + L+Q
Sbjct: 1298 KESLISQLTKSKQALTQ 1314
Score = 45.4 bits (106), Expect = 1e-04
Identities = 90/433 (20%), Positives = 180/433 (41%), Gaps = 81/433 (18%)
Query: 26 LAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVK----TRELHKDI 81
L E K ER +D + ++N +N + W + ++K + E K++
Sbjct: 800 LMRVEFKKMMER------RDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEM 853
Query: 82 EILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEES 141
+ + FER K+ + +S A+ E EE+ L+ D L +Q +L++
Sbjct: 854 ATMKEDFERT---KEELARSEARR-KELEEKMVSLLQE---KNDLQLQVQSETENLMDAE 906
Query: 142 YNME--------LEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEF 193
E LEA KE TER ++ E+ +A ++N D K +
Sbjct: 907 ERCEGLIKSKILLEAKVKEL-TERLEEEEEMNSEL-------VAKKRNLEDKCSSLKRDI 958
Query: 194 QSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFET------- 246
+ L + +EKH EN+V++L + + +N + T+++K+ E
Sbjct: 959 DDLELTLTKVE-KEKHAT----ENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD 1013
Query: 247 LQVKDEK-------------SSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYI 293
LQV+++K + ++E +++ +KL+ + +K K+ + S++ +
Sbjct: 1014 LQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDL 1073
Query: 294 RNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEIC 353
NDK+ + +L+K + + +Q +A ++ E +L+ +KI + +I +L E
Sbjct: 1074 ENDKQQIEEKLKKKEFELSQLQA-------KIDDEQVHSLQFQKKIKELQARIEELEEEI 1126
Query: 354 RKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEEL------TKVMVDYIGMENFWKR 407
T K+ ++Q LEE++E L T ++ +
Sbjct: 1127 EAEHTLRAKI----------EKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQ 1176
Query: 408 YNKVKLEQLSLQH 420
+ LE+ +LQH
Sbjct: 1177 KMRRDLEEATLQH 1189
Score = 38.1 bits (87), Expect = 0.018
Identities = 78/424 (18%), Positives = 171/424 (40%), Gaps = 85/424 (20%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKD-KLAKEEHNSALN---- 57
++ K + +SD + + K L E E KK L+ Q D ++A EE +L
Sbjct: 1504 RENKNLQEEISDLTEQIAETGKNLQEAEKTKK---LVEQEKSDLQVALEEVEGSLEHEES 1560
Query: 58 -LNKINTQWRTVLREVKTRELHKDIEI--LSQTFERVVDCKDNVI--------------K 100
+ ++ + V E+ + + KD EI L + +R + +V+ K
Sbjct: 1561 KILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKK 1620
Query: 101 SLAKDLSEAEEQYAH----------------------------ALRSHLHNVDQLLALQR 132
+ DL+E E Q H ALRS+ +QL ++R
Sbjct: 1621 KMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVER 1680
Query: 133 HRLSLLEESYNME--LEALTKEFETERKTIIDQHEK-EIHYLQDIFMAMEQNYIDSEY-E 188
LLEE M+ LE + + ++D ++ ++ + Q+ + + ++++ +
Sbjct: 1681 RNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQ 1740
Query: 189 SKLEFQSMWNDLKNM----------------NLEEKHFLRLHLENRVEDLWRKFQDVLKN 232
+ E ++ + +N L+++ HLE ++L + +D+
Sbjct: 1741 CQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800
Query: 233 YTDATE----DRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESED 288
+A + K + L+ + + E++V+ K+ + + K+ + ++E+
Sbjct: 1801 LDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEE 1860
Query: 289 ENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILK 348
+++ I ++LV K+K+ + QA A + ++N L R++ + E+ +
Sbjct: 1861 DHKNILRLQDLVDKLQAKVKSYKRQAEEAEE--------QANTQLSRCRRVQHELEEAAE 1912
Query: 349 LAEI 352
A+I
Sbjct: 1913 RADI 1916
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 58.9 bits (141), Expect = 1e-08
Identities = 80/427 (18%), Positives = 182/427 (42%), Gaps = 47/427 (11%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVK 73
+ +LLL QQ+L AE + K+ + +S L+ ++ + E + LN + WR +E K
Sbjct: 252 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR---QEEK 308
Query: 74 TRELHKDI----EILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLA 129
+E + I E + + E++ + ++ + + +++ +E+ + ++ +
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 130 LQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYES 189
Q + EE + E + ++ E R+ HE+E Q+ E+ + E
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426
Query: 190 KLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQV 249
+ E MW + + +E+ + + + +WR+ + + + E+++ E +
Sbjct: 427 EQE-AKMWRQEEKIREQEE-----KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 250 KDEKSSKEIEV--QMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKL 307
++EK ++ E+ Q +K+ + ++ I + K+ + ++ IR +E + Q K+
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Query: 308 KAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFY 367
+ Q R + + E + K+ + EKI + E K +EEK+
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEE---KVWRQEEKI---- 593
Query: 368 SSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLD 427
+EQE +K +E E WK+ K++ ++ +Q + ++ +
Sbjct: 594 ------REQE--EKRQEQE---------------EKMWKQEEKIREQEEKIQEQEEKIRE 630
Query: 428 INGKLRE 434
K+RE
Sbjct: 631 QEEKIRE 637
Score = 50.8 bits (120), Expect = 3e-06
Identities = 76/387 (19%), Positives = 165/387 (42%), Gaps = 47/387 (12%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKL-----AKEEHNSALN 57
K+EKM + E+ + ++K+ +EEM +KE + + L++K+ +E+
Sbjct: 361 KEEKMRR----QEEMMWEKEEKMRRQEEMMWEKEEKIRE-LEEKMHEQEKIREQEEKRQE 415
Query: 58 LNKINTQ----------WRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLS 107
KI Q WR +E K RE + I + R + K + + + ++
Sbjct: 416 EEKIREQEKRQEQEAKMWR---QEEKIREQEEKIREQEKKMWRQEE-KIHEQEKIREEEK 471
Query: 108 EAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKE 167
E++ +H +++ Q+ ++ EE + E + ++ E R+ E+E
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWR-QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 168 IHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLH-LENRVEDLWRKF 226
+ EQ + E E E + +W + K E+K + + + + E +WR+
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 227 QDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRES 286
+ + + E R+ E + ++EK I Q +KIQ+ ++ I + KI +
Sbjct: 591 EKI----REQEEKRQEQEEKMWKQEEK----IREQEEKIQEQEEKIREQEEKIREQEEMT 642
Query: 287 EDENRYIRNDKELVLVQLRKLKAQ-----RTQARAASQKNLVRLTLESNATLKALRKIVD 341
+++ + +E + Q K++ Q R + + Q+ +R E ++ +++
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR---EQEEKIREQEEMMQ 699
Query: 342 KGEKIL-----KLAEICRKFETEEEKV 363
+ E+ + K+ E K + +EEK+
Sbjct: 700 EQEEKMWEQEEKMCEQEEKMQEQEEKM 726
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 58.9 bits (141), Expect = 1e-08
Identities = 77/425 (18%), Positives = 185/425 (43%), Gaps = 56/425 (13%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVK 73
+ +LLL QQ+L AE + K+ + +S L+ ++ + E + LN + WR +E K
Sbjct: 252 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR---QEEK 308
Query: 74 TRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRH 133
+E + I+ + E++ + ++ + + ++ +E+ + ++++ +
Sbjct: 309 IQEWEEKIQ---EQEEKIREQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 134 RLSLLEESYNMELEALTKEFET---ERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESK 190
++ LEE E E +E E E++ I +Q EK E+ I + + +
Sbjct: 364 KMRRLEEMM-WEKEEKIRELEEKMHEQEKIREQEEKR----------QEEEKIREQEKRQ 412
Query: 191 LEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVK 250
+ MW + + +E+ + + + +WR+ + + + E+++ E + +
Sbjct: 413 EQEAKMWRQEEKIREQEE-----KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467
Query: 251 DEKSSKEIEV-QMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKA 309
+EK ++ E+ + K+ Q+ I + K+ + D+ IR +E + Q K++
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 310 QRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSS 369
Q + R +K + + + K+ ++ EK+ + K +EEK+
Sbjct: 528 QEEKIREQEEK----IREQEEMMQEQEEKMGEQEEKMQEQ----EKMRRQEEKI------ 573
Query: 370 VLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDIN 429
+EQE + E++ E+ K+ W++ K++ ++ +Q + ++ +
Sbjct: 574 ----REQEEKIREQKEKIREQEEKI----------WEQEEKIREQEEMMQEQEEKMWEQE 619
Query: 430 GKLRE 434
K+ E
Sbjct: 620 EKMCE 624
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 58.5 bits (140), Expect = 1e-08
Identities = 102/446 (22%), Positives = 186/446 (41%), Gaps = 94/446 (21%)
Query: 37 RLLSQFLKDKLAKEEHNSALNLNKINTQWRT-VLREVKTRELHKDIEILSQTFERVVDCK 95
R + L++KL ++E SAL L + N R V+ E++ R L T ER
Sbjct: 1471 RATCKSLEEKLKEKE--SALRLAEQNILSRDKVINELRLR--------LPATAER----- 1515
Query: 96 DNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFET 155
+ +I L + E E + H L+ Q +A + RL+ EE L K E
Sbjct: 1516 EKLIAELGR--KEMEPKSHHTLKI----AHQTIANMQARLNQKEEVLKKYQRLLEKAREE 1569
Query: 156 ERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLE--FQSMWNDLKNMNL---EEKHF 210
+R+ I+ +HE+++H L + ++ + +S L Q+ W+ +K KHF
Sbjct: 1570 QRE-IVKKHEEDLHIL--------HHRLELQADSSLNKFKQTAWDLMKQSPTPVPTNKHF 1620
Query: 211 LRL-------------------HLENRVEDLWR----------KFQDV----LKNYTDAT 237
+RL L+ +DL R +F+++ +N+ D
Sbjct: 1621 IRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEV 1680
Query: 238 EDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDK 297
+ KA E L+ ++S KE + ++Q ++A + + M + E ++ +
Sbjct: 1681 KKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQ 1740
Query: 298 ELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFE 357
+ L R L R + AA+++ ++ T + A L +++IVD+ + LK + E
Sbjct: 1741 QKAL--SRALLELRAEMTAAAEERIISATSQKEAHLN-VQQIVDRHTRELK-----TQVE 1792
Query: 358 TEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLS 417
E +L ++ T K +E +NL +L EL K K YNK+ E+
Sbjct: 1793 DLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQ----------KAYNKILREKEE 1842
Query: 418 LQHRRAQLLDINGKLREMLKQYLDGI 443
+ N +L+ +K+ G+
Sbjct: 1843 IDQE-------NDELKRQIKRLTSGL 1861
Score = 48.1 bits (113), Expect = 2e-05
Identities = 86/399 (21%), Positives = 165/399 (41%), Gaps = 74/399 (18%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLRE 71
+S K++ + + K L E + A+ +++ EE N L E
Sbjct: 1053 VSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFEL--------------E 1098
Query: 72 VKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALR----------SHL 121
K EL K I + +Q E+++ +D + S++K +S+A+ Q L S L
Sbjct: 1099 TKFAELTK-INLDAQKVEQML--RDELADSVSKAVSDADRQRILELEKNEMELKVEVSKL 1155
Query: 122 HNVDQLLALQRHRLSLLEESYNMELEALTKEF-----ETERKTIIDQHEKEIHYLQDIFM 176
+ + Q L+ ++S + E+E+L + +++ K++I + + LQ +
Sbjct: 1156 REISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQ-LSE 1214
Query: 177 AMEQNYIDSEYESKLEFQSMWNDLKNMNLEEK----HFLRLHLENRVEDLWRKFQDVLKN 232
A ++S SKL+ +N L+EK ++ RL NR + L + Q + +
Sbjct: 1215 ATALGKLES-ITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQ 1273
Query: 233 YTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRY 292
++ A L +++ S I++Q K+ KIM + S+ E+R
Sbjct: 1274 FSGALP--------LAQQEKFSKTMIQLQNDKL------------KIMQEMKNSQQEHRN 1313
Query: 293 IRN---DKELVLVQLRKLKAQRTQARAASQKNLVRLTLES--NATLKALRKIVDKGEKIL 347
+ N + EL L L +L + + A + + +E LK R++V E+I
Sbjct: 1314 MENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKDKEEIK 1373
Query: 348 KLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEE 386
L I ++E ++ E+E +Q+N E
Sbjct: 1374 YLNNIISEYE-----------RTISSLEEEIVQQNKFHE 1401
Score = 47.0 bits (110), Expect = 4e-05
Identities = 100/454 (22%), Positives = 191/454 (42%), Gaps = 66/454 (14%)
Query: 29 EEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQT- 87
+++ + E L + + + KE N + L K N +K L K+ +L Q+
Sbjct: 706 DQLTGRNEELRQELRESR--KEAINYSQQLAKAN---------LKIDHLEKETSLLRQSE 754
Query: 88 ----FERVVDCKDNVIKSLAKDLSEAEEQYAHALRS-------------HLHNVDQLLAL 130
+ +D D + S A ++ E H L+ L + ++ A+
Sbjct: 755 GSNVVFKGIDLPDGIAPSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAV 814
Query: 131 QRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESK 190
RH+ SLL + Y E E ++TE KTI ++ K L+D ++Q+ I +
Sbjct: 815 IRHQQSLLYKEYLSEKET----WKTESKTIKEEKRK----LED---QVQQDAIKVK---- 859
Query: 191 LEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATE-DRKAAFETLQV 249
E+ ++ N L+ M+ +E + ++ L + +++ YT E +R+ E +
Sbjct: 860 -EYNNLLNALQ-MDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEKQ 917
Query: 250 KDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKA 309
K+E S E EV +KI LQ ++ KI + + +N ++ EL Q +L A
Sbjct: 918 KNELLSMEAEV-CEKIGCLQRFKEMAIFKIA--ALQKVVDNSVSLSELELANKQYNELTA 974
Query: 310 ------QRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKV 363
Q+ NL L E N +LK + ++K +I K + E+E
Sbjct: 975 KYRDILQKDNMLVQRTSNLEHLECE-NISLKEQVESINKELEITKEKLHTIEQAWEQETK 1033
Query: 364 LPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIG----MENFWKRYNKVKLEQLSLQ 419
L SS+ K ++ I +++ +++++T + + + E+ K Y ++ SL+
Sbjct: 1034 LGNESSM--DKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLR---TSLK 1088
Query: 420 HRRAQLLDINGKLREMLKQYLDGISVSDEVLSQL 453
+ ++ K E+ K LD V + +L
Sbjct: 1089 QMEERNFELETKFAELTKINLDAQKVEQMLRDEL 1122
Score = 44.3 bits (103), Expect = 3e-04
Identities = 85/432 (19%), Positives = 188/432 (43%), Gaps = 47/432 (10%)
Query: 24 KLLAEEEMAKKKERLLSQFLKD--KLAKEEHNSALNLNKINTQWRTVLREVKTRELHK-- 79
KL E + KKK L Q + D K + + L+ ++ +R+ L + K EL +
Sbjct: 161 KLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSK-KNYELIQYL 219
Query: 80 -DIEILSQTFERVVDCKDNVIKSLAKDLSEAE---EQYAHALRSHLHNVDQLLALQRHRL 135
+I+ L++ E++ + K+L + + E E ++Y + +++ +H D ++ +L
Sbjct: 220 DEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEY-NRMKAIVHQTDNVI----DQL 274
Query: 136 SLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQS 195
+ Y ++++ LT +++ ++ + I + + + + S+ + +E+Q
Sbjct: 275 KKENDHYQLQVQELTDLLKSK-----NEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQ 329
Query: 196 MWNDL----KNMNLEEKHFLRLHLENRVEDLWRKFQ---DVLKNYTDATEDRKAAFETLQ 248
M ++L KN L+ + L+ +++ + + + ++ YT E E L+
Sbjct: 330 MLHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLK 389
Query: 249 VKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIR-NDKELVLVQLRKL 307
+ +++ + + K+Q + I K K R +E R DKELV L++L
Sbjct: 390 NELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELV-EALKRL 448
Query: 308 KAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFY 367
K + + K KI D+ +IL ++ E K+ F
Sbjct: 449 KDYESGVYGLED------AVVEIKNCKNQIKIRDREIEIL-----TKEINKLELKISDFL 497
Query: 368 SSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQL-SLQHRRAQLL 426
+E+ G++ + +LTE + + ++ N++ L+++ SL+ R L
Sbjct: 498 DENEALRERVGLEPKTMIDLTEFRNSKHL----KQQQYRAENQILLKEIESLEEER---L 550
Query: 427 DINGKLREMLKQ 438
D+ K+R+M ++
Sbjct: 551 DLKKKIRQMAQE 562
Score = 39.3 bits (90), Expect = 0.008
Identities = 108/543 (19%), Positives = 205/543 (37%), Gaps = 118/543 (21%)
Query: 2 PKKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKE----RLLSQF--LKDKLAKEEHNSA 55
P KEK AK L ++ +Q K+ K+KE L Q LKD AK +
Sbjct: 1899 PMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKL 1958
Query: 56 LNLNKINTQWRTV--------------LREVKTRELHKDIEILSQTFERVVDCKDNVIKS 101
K+ T TV L E+K R L + +IL + + +D+V++
Sbjct: 1959 TLQRKLKTTGMTVDQVLGIRALESEKELEELKKRNLDLENDILYMRAHQALP-RDSVVED 2017
Query: 102 L------------AKDLSEAEEQYAHALRSHLHNVDQLLA---LQRHRLSLLEESYNM-- 144
L A + +++ Y+ S + + D LQ+ L L E+ +
Sbjct: 2018 LHLQNRYLQEKLHALEKQFSKDTYSKPSISGIESDDHCQREQELQKENLKLSSENIELKF 2077
Query: 145 ELEALTKEF----------------------ETERKT-----------IIDQHEKEIHYL 171
+LE K+ E +RK I + EK I +
Sbjct: 2078 QLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLM 2137
Query: 172 QDIFMAMEQN---------YIDSEYESKLEFQS--MWNDLKNMNLEEKHFLRLHLENRVE 220
+ + +++ + SE + +E ++ + +L+ + H L +H E++ +
Sbjct: 2138 KKVVEKVQRENEQLKKASGILTSEKMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTK 2197
Query: 221 DLWR------KFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITI 274
+ + + LK TDA E + A L++ +EK + ++E K++Q
Sbjct: 2198 GTEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQ-------- 2249
Query: 275 SKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQ-------KNLVRLTL 327
SR + E ++ K +V+ ++ + K + + A + K LV+
Sbjct: 2250 -----FAESRGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEAT 2304
Query: 328 ESNATLKALRKIVDKGEKILKLAEICRKFETE-----EEKVLPFYSSVLTPKEQEGIQ-- 380
E + + +++ KILK + ETE E +VL + L ++ E I
Sbjct: 2305 EREQKVNKYNEDLEQQIKILK--HVPEGAETEQGLKRELQVLRLANHQLDKEKAELIHQI 2362
Query: 381 KNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYL 440
+ N ++ E T D + E ++K+ L QH + ++ + +L +
Sbjct: 2363 EANKDQSGAESTIPDADQL-KEKIKDLETQLKMSDLEKQHLKEEIKKLKKELENFDPSFF 2421
Query: 441 DGI 443
+ I
Sbjct: 2422 EEI 2424
Score = 36.2 bits (82), Expect = 0.068
Identities = 73/383 (19%), Positives = 159/383 (41%), Gaps = 40/383 (10%)
Query: 28 EEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQT 87
+EE+A LS+ ++L E+ + ++L +I L ++K +E+ +E + +
Sbjct: 21 QEELADNLLISLSKVEVNELKSEKQENVIHLFRITQS----LMKMKAQEVELALEEVEKA 76
Query: 88 FERVVDCKDNV---IKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNM 144
E ++ + + L +L A++ L N ++ L++ E +
Sbjct: 77 GEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRN--EICQLEKQL-----EQKDR 129
Query: 145 ELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYES-KLEFQSMWNDLKNM 203
ELE + KE E E+K E L++ E + + E + K + + + D+ +
Sbjct: 130 ELEDMEKELEKEKKV------NEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDY 183
Query: 204 NLEEKHFLRLHLENRVEDLWRKFQDVLKN-----YTDATEDRKAAFETLQVKDEKSSKEI 258
+ L R ED + Q KN Y D + A E ++V++++ K +
Sbjct: 184 QKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNL 243
Query: 259 EVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAAS 318
E +++++K+ D ++ K ++H ++ + ND + VQ + T +
Sbjct: 244 EESVQEMEKMTD--EYNRMKAIVHQTDNVIDQLKKENDHYQLQVQ------ELTDLLKSK 295
Query: 319 QKNLVRLTLESNATLKALRKIV-DKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQE 377
+ + + NA ++ + I+ K ++I++ ++ + + Q+
Sbjct: 296 NEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQ 355
Query: 378 GIQKNN-----LEELTEELTKVM 395
GIQ+ + L E E+ TK M
Sbjct: 356 GIQERDSQIKMLTEQVEQYTKEM 378
Score = 34.3 bits (77), Expect = 0.26
Identities = 49/234 (20%), Positives = 99/234 (42%), Gaps = 47/234 (20%)
Query: 67 TVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQ 126
T + E K +EL DI +Q+ + D +K L K+ +E E++ + + +++Q
Sbjct: 2272 TRMYETKLKELETDIAKKNQS---ITD-----LKQLVKEATEREQK----VNKYNEDLEQ 2319
Query: 127 LLALQRH--RLSLLEESYNMELEAL---TKEFETERKTIIDQHEKEIHYLQDIFMAMEQN 181
+ + +H + E+ EL+ L + + E+ +I Q E + ++
Sbjct: 2320 QIKILKHVPEGAETEQGLKRELQVLRLANHQLDKEKAELIHQIEANKD------QSGAES 2373
Query: 182 YIDSEYESKLEFQSMWNDLKNMNLEEKHF------LRLHLENRVEDLWRKFQDVLKNYTD 235
I + K + + + LK +LE++H L+ LEN + + +D+ NY
Sbjct: 2374 TIPDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKELENFDPSFFEEIEDLKYNY-- 2431
Query: 236 ATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDE 289
E+ K I ++ +K++KL + + + + S E EDE
Sbjct: 2432 ---------------KEEVKKNILLE-EKVKKLSEQLGVELTSPVAASEEFEDE 2469
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 57.8 bits (138), Expect = 2e-08
Identities = 113/512 (22%), Positives = 217/512 (42%), Gaps = 96/512 (18%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLRE 71
+ DEK F+++L EEE E+ ++ L ++A + ++ + T E
Sbjct: 1334 VEDEKNS--FREQLEEEEEAKHNLEKQIAT-LHAQVADMKKKMEDSVGCLETA-----EE 1385
Query: 72 VKTRELHKDIEILSQTFERVVDCKDNVIKS---LAKDLSEA------EEQYAHALRSHLH 122
VK R+L KD+E LSQ E V D + K+ L ++L + + Q A L
Sbjct: 1386 VK-RKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQK 1444
Query: 123 NVDQLLALQR----------------------HRLSL---LEESYNM--ELEALTKEFET 155
DQLLA ++ LSL LEE+ ELE L K+F T
Sbjct: 1445 KFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRT 1504
Query: 156 ERKTII---DQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLR 212
E + ++ D K +H L+ A+EQ E +++LE +L++ L+ +
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQV--EEMKTQLE------ELED-ELQATEDAK 1555
Query: 213 LHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAI 272
L LE ++ + +F+ L+ + +E++K + +E+E +++ +K +
Sbjct: 1556 LRLEVNLQAMKAQFERDLQGRDEQSEEKKKQL-------VRQVREMEAELEDERKQRSMA 1608
Query: 273 TISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQA------RAASQKNLVRLT 326
++ K+ + ++ E +++ + QLRKL+AQ AS++ ++
Sbjct: 1609 VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQA 1668
Query: 327 LESNATLKALRKIVDKGEKILKLAEICRKFETEE-------------------EKVLPFY 367
E+ LK++ + + ++ L AE ++ +E E+
Sbjct: 1669 KENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLE 1728
Query: 368 SSVLTPKEQEGIQKNNLEELTEELTK--VMVDYIGMENFWKRYNKVKLEQLSLQHRRAQL 425
+ + +E+ ++ N E + + L K + +D I + +R + K E Q R Q
Sbjct: 1729 ARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER-QN 1787
Query: 426 LDINGKLREM----LKQYLDGISVSDEVLSQL 453
++ KL+EM +Y I+ + ++QL
Sbjct: 1788 KELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819
Score = 42.4 bits (98), Expect = 0.001
Identities = 80/380 (21%), Positives = 160/380 (42%), Gaps = 53/380 (13%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMA-KKKERLLSQFLKDKLAK-----EEHNSAL 56
+++ + S+EK+ L +Q E E+ ++K+R ++ + KL E H +
Sbjct: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629
Query: 57 NLN---------KINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLS 107
N N K+ Q + +RE+ ++ EIL+Q E + +KS+ ++
Sbjct: 1630 NKNRDEAIKQLRKLQAQMKDCMRELDDTRASRE-EILAQAKEN-----EKKLKSMEAEMI 1683
Query: 108 EAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELE-ALTKEFETERKTIIDQHEK 166
+ +E+ A A R+ Q+ R L +E N + AL E + + I Q E+
Sbjct: 1684 QLQEELAAAERAKRQ-------AQQERDELADEIANSSGKGALALEEKRRLEARIAQLEE 1736
Query: 167 EIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHF-----LRLHLENRVED 221
E+ Q + D ++ L+ + DL NLE H R LE + ++
Sbjct: 1737 ELEEEQGNTELIN----DRLKKANLQIDQINTDL---NLERSHAQKNENARQQLERQNKE 1789
Query: 222 LWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMI 281
L K Q++ KA+ L+ K + ++++ + K+ Q + ++ K+
Sbjct: 1790 LKVKLQEMEGT---VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846
Query: 282 HSRESEDENR---YIRNDKELVLVQLRKLKAQRTQARA------ASQKNLVRLTLESNAT 332
+ +DE R ++ + +L++LK Q +A AS++ L R ++ T
Sbjct: 1847 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 1906
Query: 333 LKALRKIVDKGEKILKLAEI 352
A+ + V + L+ ++
Sbjct: 1907 ADAMNREVSSLKNKLRRGDL 1926
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 57.4 bits (137), Expect = 3e-08
Identities = 99/493 (20%), Positives = 211/493 (42%), Gaps = 56/493 (11%)
Query: 4 KEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINT 63
+E A+ E++ LL +QK + E +++LL + +KL KE+ K+
Sbjct: 1960 QELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQE--TEKLMKEKLEVQCQAEKVRD 2017
Query: 64 QWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHN 123
+ ++VK E+ D+E F + K+ + L + ++A E+ +R L
Sbjct: 2018 DLQ---KQVKALEI--DVEEQVSRFIELEQEKNTELMDLRQQ-NQALEKQLEKMRKFLD- 2070
Query: 124 VDQLLALQRHRLSLLEESYNMELEALTKEFET-ERKTIIDQHE-KEIHYLQDIFMAMEQN 181
+Q + + R + + E++ L ++ + R I +H+ +E+ L + +
Sbjct: 2071 -EQAIDREHER-----DVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHL----KE 2120
Query: 182 YIDSEYESKLEFQSMWNDLKNMN--LEEKHFLRLHLENRV---EDLWRKFQD-------- 228
D E L + + D++ N +E+ F LE + D ++K +D
Sbjct: 2121 KTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVE 2180
Query: 229 ---------VLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKI 279
L+ DA + ++ L+ + E+ +E+E + +++Q+L + I K +
Sbjct: 2181 AKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 2240
Query: 280 MIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKI 339
+E E EN+ ++D E + + +++ A TQ + ++ E + L +
Sbjct: 2241 TTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQ 2300
Query: 340 VDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVM---- 395
V K ++ LK+ + E + E + + + + K N EE E+L +V+
Sbjct: 2301 VTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQ 2360
Query: 396 --VDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQL 453
+ IG + ++ + E SL+H+ LD+ + L+Q ++ + ++E+
Sbjct: 2361 QELANIGQKTSMNAHS-LSEEADSLKHQ----LDVVIAEKLALEQQVE--TANEEMTFMK 2413
Query: 454 NPLFIVNYQSNLL 466
N L N++ N L
Sbjct: 2414 NVLKETNFKMNQL 2426
Score = 30.8 bits (68), Expect = 2.9
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 108 EAEEQYAHALRSHLHNVD-----QLLALQRHRLSLLEESYNMELEALTKEFETERKTIID 162
E E H+ ++L ++D +L +LQ + LEE ELE+L + + K
Sbjct: 1301 ETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQ-ELESLISSLQQQLKETEQ 1359
Query: 163 QHEKEIHYLQDIFMAMEQNYI 183
+E EIH LQ A+ ++ +
Sbjct: 1360 NYEAEIHCLQKRLQAVSESTV 1380
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 57.4 bits (137), Expect = 3e-08
Identities = 85/444 (19%), Positives = 182/444 (40%), Gaps = 35/444 (7%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALN-----LNKINTQWR 66
+++E+ +L Q A EE + KE++ L++KL + E + + ++ + +
Sbjct: 530 VTEEEINVLKQDLQNALEESERNKEKVRE--LEEKLVEREKGTVIKPPVEEYEEMKSSYC 587
Query: 67 TVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQ 126
+V+ + + E + E ++ KD + + ++ S+ E A+ + +++
Sbjct: 588 SVIENMNKEKAFL-FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 646
Query: 127 LLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSE 186
Q LS L + ELE K E T H+ E L + D+
Sbjct: 647 ----QVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL 702
Query: 187 YESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFET 246
E K ++ + N+L + K + EN V + V+ A ++ +
Sbjct: 703 SEMKSQYSKVLNELTQL----KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISN 756
Query: 247 LQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRES-----EDENRYIRNDKELVL 301
L K+ +SKE+EV + Q L++ ++ + S E E E + + + +
Sbjct: 757 L--KEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV 814
Query: 302 VQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEE 361
+ K+ ++ Q R S+ + V+ E+ TL K ++ E+ +KF+ +E
Sbjct: 815 KEKEKVHSEVVQIR--SEVSQVKREKENIQTLLK--------SKEQEVNELLQKFQQAQE 864
Query: 362 KVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHR 421
++ + + E + + E+++E+TK+ + + K + L+
Sbjct: 865 ELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 924
Query: 422 RAQLLDINGKLREMLKQYLDGISV 445
+ Q+ + +L E KQ+ + ISV
Sbjct: 925 QQQVKQLQNQLAECKKQHQEVISV 948
Score = 45.8 bits (107), Expect = 9e-05
Identities = 83/405 (20%), Positives = 180/405 (44%), Gaps = 50/405 (12%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKD-------------KLAKEEHNSALNLNK 60
++++ LF++ A+EE+ K K+ L SQ ++ ++ E + L++
Sbjct: 594 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 653
Query: 61 INTQWRTVLREVKTRELHKDI--EILSQTFERVVDCKDNVIKSLAKD-LSEAEEQYAHAL 117
+ + + L + + R+ +D+ E + + + NV ++ A+D LSE + QY+ L
Sbjct: 654 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 713
Query: 118 RSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMA 177
+ L + QL+ Q+ + E L+ + T +T + E++I L++ +
Sbjct: 714 -NELTQLKQLVDAQKENSVSITE----HLQVI-----TTLRTAAKEMEEKISNLKEHLAS 763
Query: 178 MEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDA- 236
E E + E +M + + + EK L+ LE+ V L K ++ +K
Sbjct: 764 KEVEVAKLEKQLLEEKAAMTDAMVPRSSYEK--LQSSLESEVSVLASKLKESVKEKEKVH 821
Query: 237 TEDRKAAFETLQVKDEK-------SSKEIEVQ--MKKIQKLQDAITISKGKIMIHSRESE 287
+E + E QVK EK SKE EV ++K Q+ Q+ + K S+ E
Sbjct: 822 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 881
Query: 288 DENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKIL 347
D+++ I + ++ KLK + +L +L+ ++++ + +++ +++
Sbjct: 882 DKDKKINEMSK----EVTKLK--------EALNSLSQLSYSTSSSKRQSQQLEALQQQVK 929
Query: 348 KLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELT 392
+L + + + ++V+ Y L Q + ++ + L + LT
Sbjct: 930 QLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILT 974
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 57.4 bits (137), Expect = 3e-08
Identities = 85/444 (19%), Positives = 182/444 (40%), Gaps = 35/444 (7%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALN-----LNKINTQWR 66
+++E+ +L Q A EE + KE++ L++KL + E + + ++ + +
Sbjct: 519 VTEEEINVLKQDLQNALEESERNKEKVRE--LEEKLVEREKGTVIKPPVEEYEEMKSSYC 576
Query: 67 TVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQ 126
+V+ + + E + E ++ KD + + ++ S+ E A+ + +++
Sbjct: 577 SVIENMNKEKAFL-FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 635
Query: 127 LLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSE 186
Q LS L + ELE K E T H+ E L + D+
Sbjct: 636 ----QVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL 691
Query: 187 YESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFET 246
E K ++ + N+L + K + EN V + V+ A ++ +
Sbjct: 692 SEMKSQYSKVLNELTQL----KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISN 745
Query: 247 LQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRES-----EDENRYIRNDKELVL 301
L K+ +SKE+EV + Q L++ ++ + S E E E + + + +
Sbjct: 746 L--KEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV 803
Query: 302 VQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEE 361
+ K+ ++ Q R S+ + V+ E+ TL K ++ E+ +KF+ +E
Sbjct: 804 KEKEKVHSEVVQIR--SEVSQVKREKENIQTLLK--------SKEQEVNELLQKFQQAQE 853
Query: 362 KVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHR 421
++ + + E + + E+++E+TK+ + + K + L+
Sbjct: 854 ELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 913
Query: 422 RAQLLDINGKLREMLKQYLDGISV 445
+ Q+ + +L E KQ+ + ISV
Sbjct: 914 QQQVKQLQNQLAECKKQHQEVISV 937
Score = 45.8 bits (107), Expect = 9e-05
Identities = 83/405 (20%), Positives = 180/405 (44%), Gaps = 50/405 (12%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKD-------------KLAKEEHNSALNLNK 60
++++ LF++ A+EE+ K K+ L SQ ++ ++ E + L++
Sbjct: 583 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 642
Query: 61 INTQWRTVLREVKTRELHKDI--EILSQTFERVVDCKDNVIKSLAKD-LSEAEEQYAHAL 117
+ + + L + + R+ +D+ E + + + NV ++ A+D LSE + QY+ L
Sbjct: 643 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 702
Query: 118 RSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMA 177
+ L + QL+ Q+ + E L+ + T +T + E++I L++ +
Sbjct: 703 -NELTQLKQLVDAQKENSVSITE----HLQVI-----TTLRTAAKEMEEKISNLKEHLAS 752
Query: 178 MEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDA- 236
E E + E +M + + + EK L+ LE+ V L K ++ +K
Sbjct: 753 KEVEVAKLEKQLLEEKAAMTDAMVPRSSYEK--LQSSLESEVSVLASKLKESVKEKEKVH 810
Query: 237 TEDRKAAFETLQVKDEK-------SSKEIEVQ--MKKIQKLQDAITISKGKIMIHSRESE 287
+E + E QVK EK SKE EV ++K Q+ Q+ + K S+ E
Sbjct: 811 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 870
Query: 288 DENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKIL 347
D+++ I + ++ KLK + +L +L+ ++++ + +++ +++
Sbjct: 871 DKDKKINEMSK----EVTKLK--------EALNSLSQLSYSTSSSKRQSQQLEALQQQVK 918
Query: 348 KLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELT 392
+L + + + ++V+ Y L Q + ++ + L + LT
Sbjct: 919 QLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILT 963
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 57.4 bits (137), Expect = 3e-08
Identities = 85/444 (19%), Positives = 182/444 (40%), Gaps = 35/444 (7%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALN-----LNKINTQWR 66
+++E+ +L Q A EE + KE++ L++KL + E + + ++ + +
Sbjct: 498 VTEEEINVLKQDLQNALEESERNKEKVRE--LEEKLVEREKGTVIKPPVEEYEEMKSSYC 555
Query: 67 TVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQ 126
+V+ + + E + E ++ KD + + ++ S+ E A+ + +++
Sbjct: 556 SVIENMNKEKAFL-FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 614
Query: 127 LLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSE 186
Q LS L + ELE K E T H+ E L + D+
Sbjct: 615 ----QVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL 670
Query: 187 YESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFET 246
E K ++ + N+L + K + EN V + V+ A ++ +
Sbjct: 671 SEMKSQYSKVLNELTQL----KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISN 724
Query: 247 LQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRES-----EDENRYIRNDKELVL 301
L K+ +SKE+EV + Q L++ ++ + S E E E + + + +
Sbjct: 725 L--KEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV 782
Query: 302 VQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEE 361
+ K+ ++ Q R S+ + V+ E+ TL K ++ E+ +KF+ +E
Sbjct: 783 KEKEKVHSEVVQIR--SEVSQVKREKENIQTLLK--------SKEQEVNELLQKFQQAQE 832
Query: 362 KVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHR 421
++ + + E + + E+++E+TK+ + + K + L+
Sbjct: 833 ELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 892
Query: 422 RAQLLDINGKLREMLKQYLDGISV 445
+ Q+ + +L E KQ+ + ISV
Sbjct: 893 QQQVKQLQNQLAECKKQHQEVISV 916
Score = 45.8 bits (107), Expect = 9e-05
Identities = 83/405 (20%), Positives = 180/405 (44%), Gaps = 50/405 (12%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKD-------------KLAKEEHNSALNLNK 60
++++ LF++ A+EE+ K K+ L SQ ++ ++ E + L++
Sbjct: 562 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 621
Query: 61 INTQWRTVLREVKTRELHKDI--EILSQTFERVVDCKDNVIKSLAKD-LSEAEEQYAHAL 117
+ + + L + + R+ +D+ E + + + NV ++ A+D LSE + QY+ L
Sbjct: 622 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 681
Query: 118 RSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMA 177
+ L + QL+ Q+ + E L+ + T +T + E++I L++ +
Sbjct: 682 -NELTQLKQLVDAQKENSVSITE----HLQVI-----TTLRTAAKEMEEKISNLKEHLAS 731
Query: 178 MEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDA- 236
E E + E +M + + + EK L+ LE+ V L K ++ +K
Sbjct: 732 KEVEVAKLEKQLLEEKAAMTDAMVPRSSYEK--LQSSLESEVSVLASKLKESVKEKEKVH 789
Query: 237 TEDRKAAFETLQVKDEK-------SSKEIEVQ--MKKIQKLQDAITISKGKIMIHSRESE 287
+E + E QVK EK SKE EV ++K Q+ Q+ + K S+ E
Sbjct: 790 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 849
Query: 288 DENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKIL 347
D+++ I + ++ KLK + +L +L+ ++++ + +++ +++
Sbjct: 850 DKDKKINEMSK----EVTKLK--------EALNSLSQLSYSTSSSKRQSQQLEALQQQVK 897
Query: 348 KLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELT 392
+L + + + ++V+ Y L Q + ++ + L + LT
Sbjct: 898 QLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILT 942
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 57.4 bits (137), Expect = 3e-08
Identities = 85/444 (19%), Positives = 182/444 (40%), Gaps = 35/444 (7%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALN-----LNKINTQWR 66
+++E+ +L Q A EE + KE++ L++KL + E + + ++ + +
Sbjct: 527 VTEEEINVLKQDLQNALEESERNKEKVRE--LEEKLVEREKGTVIKPPVEEYEEMKSSYC 584
Query: 67 TVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQ 126
+V+ + + E + E ++ KD + + ++ S+ E A+ + +++
Sbjct: 585 SVIENMNKEKAFL-FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 643
Query: 127 LLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSE 186
Q LS L + ELE K E T H+ E L + D+
Sbjct: 644 ----QVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL 699
Query: 187 YESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFET 246
E K ++ + N+L + K + EN V + V+ A ++ +
Sbjct: 700 SEMKSQYSKVLNELTQL----KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISN 753
Query: 247 LQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRES-----EDENRYIRNDKELVL 301
L K+ +SKE+EV + Q L++ ++ + S E E E + + + +
Sbjct: 754 L--KEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV 811
Query: 302 VQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEE 361
+ K+ ++ Q R S+ + V+ E+ TL K ++ E+ +KF+ +E
Sbjct: 812 KEKEKVHSEVVQIR--SEVSQVKREKENIQTLLK--------SKEQEVNELLQKFQQAQE 861
Query: 362 KVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHR 421
++ + + E + + E+++E+TK+ + + K + L+
Sbjct: 862 ELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 921
Query: 422 RAQLLDINGKLREMLKQYLDGISV 445
+ Q+ + +L E KQ+ + ISV
Sbjct: 922 QQQVKQLQNQLAECKKQHQEVISV 945
Score = 45.8 bits (107), Expect = 9e-05
Identities = 83/405 (20%), Positives = 180/405 (44%), Gaps = 50/405 (12%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKD-------------KLAKEEHNSALNLNK 60
++++ LF++ A+EE+ K K+ L SQ ++ ++ E + L++
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 650
Query: 61 INTQWRTVLREVKTRELHKDI--EILSQTFERVVDCKDNVIKSLAKD-LSEAEEQYAHAL 117
+ + + L + + R+ +D+ E + + + NV ++ A+D LSE + QY+ L
Sbjct: 651 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 118 RSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMA 177
+ L + QL+ Q+ + E L+ + T +T + E++I L++ +
Sbjct: 711 -NELTQLKQLVDAQKENSVSITE----HLQVI-----TTLRTAAKEMEEKISNLKEHLAS 760
Query: 178 MEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDA- 236
E E + E +M + + + EK L+ LE+ V L K ++ +K
Sbjct: 761 KEVEVAKLEKQLLEEKAAMTDAMVPRSSYEK--LQSSLESEVSVLASKLKESVKEKEKVH 818
Query: 237 TEDRKAAFETLQVKDEK-------SSKEIEVQ--MKKIQKLQDAITISKGKIMIHSRESE 287
+E + E QVK EK SKE EV ++K Q+ Q+ + K S+ E
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 878
Query: 288 DENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKIL 347
D+++ I + ++ KLK + +L +L+ ++++ + +++ +++
Sbjct: 879 DKDKKINEMSK----EVTKLK--------EALNSLSQLSYSTSSSKRQSQQLEALQQQVK 926
Query: 348 KLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELT 392
+L + + + ++V+ Y L Q + ++ + L + LT
Sbjct: 927 QLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILT 971
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 57.4 bits (137), Expect = 3e-08
Identities = 85/444 (19%), Positives = 182/444 (40%), Gaps = 35/444 (7%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALN-----LNKINTQWR 66
+++E+ +L Q A EE + KE++ L++KL + E + + ++ + +
Sbjct: 527 VTEEEINVLKQDLQNALEESERNKEKVRE--LEEKLVEREKGTVIKPPVEEYEEMKSSYC 584
Query: 67 TVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQ 126
+V+ + + E + E ++ KD + + ++ S+ E A+ + +++
Sbjct: 585 SVIENMNKEKAFL-FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 643
Query: 127 LLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSE 186
Q LS L + ELE K E T H+ E L + D+
Sbjct: 644 ----QVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL 699
Query: 187 YESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFET 246
E K ++ + N+L + K + EN V + V+ A ++ +
Sbjct: 700 SEMKSQYSKVLNELTQL----KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISN 753
Query: 247 LQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRES-----EDENRYIRNDKELVL 301
L K+ +SKE+EV + Q L++ ++ + S E E E + + + +
Sbjct: 754 L--KEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV 811
Query: 302 VQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEE 361
+ K+ ++ Q R S+ + V+ E+ TL K ++ E+ +KF+ +E
Sbjct: 812 KEKEKVHSEVVQIR--SEVSQVKREKENIQTLLK--------SKEQEVNELLQKFQQAQE 861
Query: 362 KVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHR 421
++ + + E + + E+++E+TK+ + + K + L+
Sbjct: 862 ELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 921
Query: 422 RAQLLDINGKLREMLKQYLDGISV 445
+ Q+ + +L E KQ+ + ISV
Sbjct: 922 QQQVKQLQNQLAECKKQHQEVISV 945
Score = 45.8 bits (107), Expect = 9e-05
Identities = 83/405 (20%), Positives = 180/405 (44%), Gaps = 50/405 (12%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKD-------------KLAKEEHNSALNLNK 60
++++ LF++ A+EE+ K K+ L SQ ++ ++ E + L++
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 650
Query: 61 INTQWRTVLREVKTRELHKDI--EILSQTFERVVDCKDNVIKSLAKD-LSEAEEQYAHAL 117
+ + + L + + R+ +D+ E + + + NV ++ A+D LSE + QY+ L
Sbjct: 651 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 118 RSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMA 177
+ L + QL+ Q+ + E L+ + T +T + E++I L++ +
Sbjct: 711 -NELTQLKQLVDAQKENSVSITE----HLQVI-----TTLRTAAKEMEEKISNLKEHLAS 760
Query: 178 MEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDA- 236
E E + E +M + + + EK L+ LE+ V L K ++ +K
Sbjct: 761 KEVEVAKLEKQLLEEKAAMTDAMVPRSSYEK--LQSSLESEVSVLASKLKESVKEKEKVH 818
Query: 237 TEDRKAAFETLQVKDEK-------SSKEIEVQ--MKKIQKLQDAITISKGKIMIHSRESE 287
+E + E QVK EK SKE EV ++K Q+ Q+ + K S+ E
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 878
Query: 288 DENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKIL 347
D+++ I + ++ KLK + +L +L+ ++++ + +++ +++
Sbjct: 879 DKDKKINEMSK----EVTKLK--------EALNSLSQLSYSTSSSKRQSQQLEALQQQVK 926
Query: 348 KLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELT 392
+L + + + ++V+ Y L Q + ++ + L + LT
Sbjct: 927 QLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILT 971
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 57.4 bits (137), Expect = 3e-08
Identities = 85/444 (19%), Positives = 182/444 (40%), Gaps = 35/444 (7%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALN-----LNKINTQWR 66
+++E+ +L Q A EE + KE++ L++KL + E + + ++ + +
Sbjct: 527 VTEEEINVLKQDLQNALEESERNKEKVRE--LEEKLVEREKGTVIKPPVEEYEEMKSSYC 584
Query: 67 TVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQ 126
+V+ + + E + E ++ KD + + ++ S+ E A+ + +++
Sbjct: 585 SVIENMNKEKAFL-FEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNK 643
Query: 127 LLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSE 186
Q LS L + ELE K E T H+ E L + D+
Sbjct: 644 ----QVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL 699
Query: 187 YESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFET 246
E K ++ + N+L + K + EN V + V+ A ++ +
Sbjct: 700 SEMKSQYSKVLNELTQL----KQLVDAQKENSVSIT--EHLQVITTLRTAAKEMEEKISN 753
Query: 247 LQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRES-----EDENRYIRNDKELVL 301
L K+ +SKE+EV + Q L++ ++ + S E E E + + + +
Sbjct: 754 L--KEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESV 811
Query: 302 VQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEE 361
+ K+ ++ Q R S+ + V+ E+ TL K ++ E+ +KF+ +E
Sbjct: 812 KEKEKVHSEVVQIR--SEVSQVKREKENIQTLLK--------SKEQEVNELLQKFQQAQE 861
Query: 362 KVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHR 421
++ + + E + + E+++E+TK+ + + K + L+
Sbjct: 862 ELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEAL 921
Query: 422 RAQLLDINGKLREMLKQYLDGISV 445
+ Q+ + +L E KQ+ + ISV
Sbjct: 922 QQQVKQLQNQLAECKKQHQEVISV 945
Score = 45.8 bits (107), Expect = 9e-05
Identities = 83/405 (20%), Positives = 180/405 (44%), Gaps = 50/405 (12%)
Query: 14 DEKQLLLFQQKLLAEEEMAKKKERLLSQFLKD-------------KLAKEEHNSALNLNK 60
++++ LF++ A+EE+ K K+ L SQ ++ ++ E + L++
Sbjct: 591 NKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQ 650
Query: 61 INTQWRTVLREVKTRELHKDI--EILSQTFERVVDCKDNVIKSLAKD-LSEAEEQYAHAL 117
+ + + L + + R+ +D+ E + + + NV ++ A+D LSE + QY+ L
Sbjct: 651 LYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 118 RSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMA 177
+ L + QL+ Q+ + E L+ + T +T + E++I L++ +
Sbjct: 711 -NELTQLKQLVDAQKENSVSITE----HLQVI-----TTLRTAAKEMEEKISNLKEHLAS 760
Query: 178 MEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDA- 236
E E + E +M + + + EK L+ LE+ V L K ++ +K
Sbjct: 761 KEVEVAKLEKQLLEEKAAMTDAMVPRSSYEK--LQSSLESEVSVLASKLKESVKEKEKVH 818
Query: 237 TEDRKAAFETLQVKDEK-------SSKEIEVQ--MKKIQKLQDAITISKGKIMIHSRESE 287
+E + E QVK EK SKE EV ++K Q+ Q+ + K S+ E
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 878
Query: 288 DENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKIL 347
D+++ I + ++ KLK + +L +L+ ++++ + +++ +++
Sbjct: 879 DKDKKINEMSK----EVTKLK--------EALNSLSQLSYSTSSSKRQSQQLEALQQQVK 926
Query: 348 KLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELT 392
+L + + + ++V+ Y L Q + ++ + L + LT
Sbjct: 927 QLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILT 971
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 57.0 bits (136), Expect = 4e-08
Identities = 110/445 (24%), Positives = 182/445 (40%), Gaps = 61/445 (13%)
Query: 29 EEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQTF 88
EE +K E SQ L+ K + EE L R E + R LH IE LS
Sbjct: 1114 EETTQKAE---SQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKV 1170
Query: 89 ERVVDCKDNVIKSLAKDLSE---AEEQYAHALR---------SHLHNVDQLLALQ-RHRL 135
V K+ V L LSE ++EQ LR V Q+ +L+ R R+
Sbjct: 1171 --VASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRV 1228
Query: 136 SLLEESYNMELEALTKEFETERKTI------IDQHEKEIHYLQDIFMAMEQNYIDSEYES 189
LLE EL+ L ER+ + + QHE+ + + + + ME N + E +
Sbjct: 1229 ELLER----ELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKE 1284
Query: 190 KLE--FQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRK---FQDVLKNYTDATEDRKAAF 244
+LE Q M ++ + L+ L L+ +L K Q K + + KA
Sbjct: 1285 RLEQDLQQMQAKVRKLELDI-----LPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARN 1339
Query: 245 ETL--QVKD------EKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRND 296
+ L Q KD K E EV K+IQ+L + I K +I N + N+
Sbjct: 1340 QHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIA-------RSNASLTNN 1392
Query: 297 KELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKF 356
+ L+ L RT+ + QK+L ++ +K + ++ G + E +
Sbjct: 1393 QNLIQSLKEDLNKVRTE-KETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYE---EL 1448
Query: 357 ETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEEL----TKVMVDYIGMENFWKRYNKVK 412
+ +++KV+ + +++ + ++EL E L TK +EN K ++ +
Sbjct: 1449 KAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKE 1508
Query: 413 LEQLSLQHRRAQLLDINGKLREMLK 437
E +LQ + QL +LR+ L+
Sbjct: 1509 TEARNLQEQTVQLQSELSRLRQDLQ 1533
Score = 51.6 bits (122), Expect = 2e-06
Identities = 86/419 (20%), Positives = 178/419 (42%), Gaps = 62/419 (14%)
Query: 23 QKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRE------ 76
+ L E+EM K E LSQ + LA++ + L N Q E +T++
Sbjct: 782 ENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQI 841
Query: 77 --LHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHR 134
L +I L + E V+ + + ++L L + + Q HL+ + L Q+
Sbjct: 842 EKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEI 901
Query: 135 LSLLEESYNMELEALT-------------KEFETERKTIIDQHEKEIHYLQDIFMAMEQN 181
+L + NME++ + KE + + + Q E++++ L++ N
Sbjct: 902 ATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSN 961
Query: 182 YIDSEYESKL-EFQSMWNDLKNMNLEEKHFLRLHLENRVE---DLWRKFQDVLKNYTDAT 237
+Y++ + + N K + E + + + L+ E L +K +V K +
Sbjct: 962 V--EQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQ 1019
Query: 238 EDRKAAFETL-----QVKDEKSSKEIEVQMKKIQKLQDAIT---------ISKGKIMIHS 283
+D++ A E++ ++K SS + EVQ + +Q+ A++ + KI +
Sbjct: 1020 DDKRRAIESMEQQLSELKKTLSSVQNEVQ-EALQRASTALSNEQQARRDCQEQAKIAV-- 1076
Query: 284 RESEDENRYIRNDKELVL----VQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKI 339
E +N+Y ++EL+L V+ + ++ A+ +++L T ++ + L +
Sbjct: 1077 ---EAQNKY---ERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKAS 1130
Query: 340 VDKGEKILK---LAEICRKFETEEEKVL-----PFYSSVLTPKEQEGIQKNNLEELTEE 390
++ E++LK +CR + E++ L S + +EG+Q L+EE
Sbjct: 1131 WEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEE 1189
Score = 51.2 bits (121), Expect = 2e-06
Identities = 84/445 (18%), Positives = 189/445 (42%), Gaps = 50/445 (11%)
Query: 23 QKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIE 82
Q L ++ M +KE+ Q L+D + + L+++ +V EV+ L +
Sbjct: 1001 QTQLEKKLMEVEKEK---QELQDDKRRAIESMEQQLSELKKTLSSVQNEVQ-EALQRAST 1056
Query: 83 ILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESY 142
LS + DC++ AK EA+ +Y L H +V+ L A + + S
Sbjct: 1057 ALSNEQQARRDCQEQ-----AKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMA--SV 1109
Query: 143 NMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKN 202
LE T++ E++ E+ L+D D E +++L +
Sbjct: 1110 RQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDK 1169
Query: 203 MNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAA---FETLQVKDEKSSKEIE 259
+ K ++ L + + + + +L+ +++ A FE QV+ + + +E
Sbjct: 1170 VVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVE 1229
Query: 260 VQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLV-----QLRKLKAQRTQA 314
+ +++Q+LQD++ + K+ + ++ ++ + + +V LR+ K + Q
Sbjct: 1230 LLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQD 1289
Query: 315 RAASQKNLVRLTL------ESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVL---- 364
Q + +L L E+NA L ++ +K+L+ E ++++ + ++
Sbjct: 1290 LQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLE--EDVKRWKARNQHLVSQQK 1347
Query: 365 ----PFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIG-----------MENFWKRYN 409
Y +L+ KE + +++LTEE+ ++ + +++ + N
Sbjct: 1348 DPDTEEYRKLLSEKE---VHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLN 1404
Query: 410 KVKLEQLSLQ-HRRAQLLDINGKLR 433
KV+ E+ ++Q A+++DI K++
Sbjct: 1405 KVRTEKETIQKDLDAKIIDIQEKVK 1429
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/280 (20%), Positives = 120/280 (42%), Gaps = 38/280 (13%)
Query: 130 LQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYES 189
L+R L+ L +S +LE + ++E + +HEK + EQ Y + E
Sbjct: 9 LERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEK-------FKVESEQQYFEIEKRL 61
Query: 190 KLEFQSMWNDLKNMNLEEKHFLRLHLE---NRVEDLWRKFQD----------VLKNYTDA 236
+ + N+ + E LRL LE N+++ L K ++ + +T
Sbjct: 62 SHSQERLVNETR-----ECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRT 116
Query: 237 TEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAI---TISKGKIMIHSRESEDEN--- 290
E+ +A L +E+ S+E+E + +++L + + +KG++ + E + +
Sbjct: 117 KEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSV 176
Query: 291 ----RYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKI 346
+ + +KEL+ Q L T+ + + + L + N L+ + +K E++
Sbjct: 177 KYREKRLEQEKELLHSQNTWL---NTELKTKTDELLALGREKGNEILELKCNLENKKEEV 233
Query: 347 LKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEE 386
+L E +T E + +LT ++ Q+ ++EE
Sbjct: 234 SRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 273
Score = 41.2 bits (95), Expect = 0.002
Identities = 94/433 (21%), Positives = 171/433 (39%), Gaps = 69/433 (15%)
Query: 15 EKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKT 74
E++L Q L AE E + + ++Q + E N + NK+ LRE K
Sbjct: 1232 ERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKM-------LREEKE 1284
Query: 75 RELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHR 134
R L +D++ + Q R ++ ++ +LSE + +V + A +H
Sbjct: 1285 R-LEQDLQQM-QAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHL 1342
Query: 135 LSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQ------DIFMAMEQNYIDSEYE 188
+S ++ E L E E K I Q +EI L+ + + QN I S E
Sbjct: 1343 VSQQKDPDTEEYRKLLSEKEVHTKRI-QQLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1401
Query: 189 S----KLEFQSMWNDL--KNMNLEEK-------HFLRLHLENRVEDLWRKFQDVLKNYTD 235
+ E +++ DL K ++++EK + + + E+L + V++
Sbjct: 1402 DLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQ 1461
Query: 236 ATEDRKAAFETLQVKDE---------KSSKEIEVQMKKIQKLQDAITISKGKIMIHSRES 286
++ D + ++Q E SK +E Q++ +QK T+S E
Sbjct: 1462 SSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQK-----TLS---------EK 1507
Query: 287 EDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKI 346
E E R ++ + +L +L+ Q Q R ++ L + E K + IV KI
Sbjct: 1508 ETEARNLQEQTVQLQSELSRLR-QDLQDRTTQEEQLRQQITEKEE--KTRKAIVAAKSKI 1564
Query: 347 LKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIG----ME 402
LA + + E E++ K++ G +EL +T + Y G +E
Sbjct: 1565 AHLAGVKDQLTKENEEL----------KQRNGALDQQKDELDVRITALKSQYEGRISRLE 1614
Query: 403 NFWKRYNKVKLEQ 415
+ + + LEQ
Sbjct: 1615 RELREHQERHLEQ 1627
Score = 33.1 bits (74), Expect = 0.58
Identities = 89/432 (20%), Positives = 164/432 (37%), Gaps = 62/432 (14%)
Query: 4 KEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINT 63
KE AK P+ ++ E E A+K LS L+ + KE + +K N
Sbjct: 428 KEVEAKAPILKRQR---------EEYERAQKAVASLSVKLEQAM-KEIQRLQEDTDKANK 477
Query: 64 QWRTVLR-----EVKTRELHKDIEILSQTFERVVD---CKDNVIKSLAKDLSEAEEQYAH 115
Q + R E++ ++L + I +L E +D + S D+S + E +
Sbjct: 478 QSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSA--DISSSSEVISQ 535
Query: 116 ALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIF 175
L S+ N+++L + L L E T+E E + T E ++ L+
Sbjct: 536 HLVSY-RNIEELQQQNQRLLVALRELGE------TREREEQETTSSKITELQLK-LESAL 587
Query: 176 MAMEQNYIDSEYESKLEFQSM-WNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYT 234
+EQ +++ +L + D+ + L + + + L D + T
Sbjct: 588 TELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPST 647
Query: 235 DATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIR 294
T A + V + + E + +K++Q++ + + ++ + EN I+
Sbjct: 648 SQTVSTPAP---VPVIESTEAIEAKAALKQLQEIFE-----------NYKKEKAENEKIQ 693
Query: 295 NDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICR 354
N+ QL KL+ Q T R+ + K +L S + +I L E +
Sbjct: 694 NE------QLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQ 747
Query: 355 KFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLE 414
K T ++QE I ++L K+ V + EN K +KL
Sbjct: 748 KLTA-------------TTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLS 794
Query: 415 QLSLQHRRAQLL 426
++ L +R LL
Sbjct: 795 EVRLSQQRESLL 806
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 57.0 bits (136), Expect = 4e-08
Identities = 97/445 (21%), Positives = 186/445 (41%), Gaps = 44/445 (9%)
Query: 15 EKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALN--LNKINTQWRTVLREV 72
+++L + Q+KL EE + +++ ++ A E+ N L+ L ++ + T+ V
Sbjct: 251 QQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTV 310
Query: 73 KTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQR 132
+T ++ +IL + E V + +L +++ EQ+ A Q A
Sbjct: 311 ETER--EESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQA--------GQAQAELE 360
Query: 133 HRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLE 192
R S LE+ + E+E T + +KT + + L+D + Q+ + +S
Sbjct: 361 SRYSALEQKHKAEMEEKTSHILSLQKT-GQELQSACDALKDQNSKLLQDKNEQAVQSAQT 419
Query: 193 FQSMWNDLKNMNLEEKHFL-RLHLENRVEDLWRKFQDVLKNYTDA-TEDRKAAFE--TLQ 248
Q + + L+ + E FL RL L+ F DV T A TE+ A+ + ++
Sbjct: 420 IQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVE 479
Query: 249 VKDEK-----SSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQ 303
+++EK SS E+E + +KL IT+ E +NR D+E+ +
Sbjct: 480 LENEKGALLLSSIELEELKAENEKLSSQITL-----------LEAQNRTGEADREVSEIS 528
Query: 304 LRKLKAQRTQARAASQKNLVRLTLESN----ATLKALRKIVDKGEKILKLAEICRKFETE 359
+ + +R+ + S ++++ T + L K + LKL ++ E
Sbjct: 529 IVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEA 588
Query: 360 EEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQ 419
+ +VL + E EGI ++ E+ + D+ M N V+ EQ S +
Sbjct: 589 DHEVLD--QKEMKQMEGEGIAPIKMKVFLEDTGQ---DFPLMPNEESSLPAVEKEQASTE 643
Query: 420 H--RRAQLLDINGKLREMLKQYLDG 442
H R ++ + +N E+ DG
Sbjct: 644 HQSRTSEEISLNDAGVELKSTKQDG 668
Score = 52.4 bits (124), Expect = 9e-07
Identities = 107/526 (20%), Positives = 209/526 (39%), Gaps = 84/526 (15%)
Query: 10 TPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQF------LKDKLAKEEHNSALNLNKINT 63
T L +E L L+ +L +EE + L S L+++L + +A + +I
Sbjct: 2619 TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIED 2678
Query: 64 QWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHN 123
+ + L+ LH D I+ E + + LA+DL E E++ + +
Sbjct: 2679 KLKKELKH-----LHHDAGIMRNETETA----EERVAELARDLVEMEQKLLMVTKENKGL 2729
Query: 124 VDQLLALQRHRLSLLE--ESYNMELEALTKEFETERKTIIDQHEKEI-HYLQDIFMAMEQ 180
Q+ + R SL + N EL+ L ++++ K + E+ + + +D ++
Sbjct: 2730 TAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETA 2789
Query: 181 NYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDV------LKNYT 234
++S E+ L + N L K LHL +++ED + + Q L+N
Sbjct: 2790 FSMNSTEENSLSHL----EKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNER 2845
Query: 235 DATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAI-TISKGKIMIHSRESEDENRYI 293
D + F + ++S+ + ++Q L+ A+ ++ + + + +Y+
Sbjct: 2846 DHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYL 2905
Query: 294 RNDKELVLVQLRKLKAQ------RTQARAASQKNLVRLTLESNATLKALR---------- 337
+ ++E + +L LKAQ +T+A Q+ L + L L LR
Sbjct: 2906 QINQE--ITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHE 2963
Query: 338 ---------KIVDKGEKILKLAEICRKFETEEEKVLPF------YSSVLTPKEQEGIQKN 382
I DK +++ L + R+ + + P +S T +G Q
Sbjct: 2964 RRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNL 3023
Query: 383 NLE------ELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREML 436
E +L + L ++ + ++ ++++ E+ +L QL D + LRE
Sbjct: 3024 VYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLS---IQLCDTSQSLRENQ 3080
Query: 437 KQYLDGISVSDEVLSQLNPLFIVNYQSNLLQ--PLSIRIAHPGDKQ 480
+ Y D LN ++ Q LQ PL+I +A PG Q
Sbjct: 3081 QHYGD----------LLNHCAVLEKQVQELQAGPLNIDVA-PGAPQ 3115
Score = 47.4 bits (111), Expect = 3e-05
Identities = 88/444 (19%), Positives = 179/444 (40%), Gaps = 53/444 (11%)
Query: 12 LSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLRE 71
L +KQ+ ++ K E ++ +K L K+ L++ E L + N + E
Sbjct: 2257 LEHDKQI--WESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKL---E 2311
Query: 72 VKTRELHKDIEILSQTFERVVDCKDN---VIKSLAKDLSEAEEQYAHALRSHLHNVDQLL 128
+ + L + LS + E+ + K N +I+ D+ ++ Y L + L +L
Sbjct: 2312 SELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQ-LETDLQASRELT 2370
Query: 129 ALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYE 188
+ +++ E+ L + + + QH+KEI L+++ E+ I E E
Sbjct: 2371 SRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEE 2430
Query: 189 SKL------EFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKA 242
+K + +K N+++K + +K+ + DR
Sbjct: 2431 NKKAVDKTNQLMETLKTIKKENIQQK---------------AQLDSFVKSMSSLQNDRDR 2475
Query: 243 AFETLQVKDEKSSKEIEVQMKKIQKLQDAIT-ISKGKIMIHSRESEDENRYIRNDK-ELV 300
Q +E + + + ++K Q +Q+A +K K I S ++ N K +
Sbjct: 2476 IVGDYQQLEE---RHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE 2532
Query: 301 LVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEE 360
L+Q R+ Q + + QK L+ + L+ N L+ K KL E ++ E
Sbjct: 2533 LIQYREDLNQVITIKDSQQKQLLEVQLQQNKELE---------NKYAKLEEKLKESEEAN 2583
Query: 361 EKVLPFYSSVLTPKEQEGIQ----KNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQL 416
E + ++++ K+ + K ++ +LT ++T + + G + KVK E++
Sbjct: 2584 EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE--GTLGLYHAQLKVKEEEV 2641
Query: 417 SLQHRRAQLLDINGKLREMLKQYL 440
HR + L + K L++ L
Sbjct: 2642 ---HRLSALFSSSQKRIAELEEEL 2662
Score = 47.0 bits (110), Expect = 4e-05
Identities = 91/428 (21%), Positives = 167/428 (39%), Gaps = 44/428 (10%)
Query: 44 KDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLA 103
K+KL KE + + +T+W+ K +EL K+ EIL Q++E V + + + +
Sbjct: 1583 KEKLVKEIESLKSSKIAESTEWQE-----KHKELQKEYEILLQSYENVSNEAERIQHVVE 1637
Query: 104 KDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKE---FETERKTI 160
E +E Y + + + LQ + E M A +K+ E E +
Sbjct: 1638 AVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEEN- 1696
Query: 161 IDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVE 220
D+ E+H D + + S K E + + + + ++ K F L E +
Sbjct: 1697 -DRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLS---KKFQSLMSEK--D 1750
Query: 221 DLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKS--SKEIEVQMKKIQKLQDAITISKGK 278
L + QD LK+ + ++A E + D ++ ++E + + QD++++S
Sbjct: 1751 SLSEEVQD-LKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRP 1809
Query: 279 IMIHSRES-EDENRYIRNDKEL------VLVQLRKLKAQRTQARAASQKNLVRLTLESNA 331
S S + N + D L Q+ +LK + QKN N
Sbjct: 1810 TCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENE 1869
Query: 332 TLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEE----- 386
L +I K ++ L E K +++ S V KE +K++LEE
Sbjct: 1870 KNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQ 1929
Query: 387 ----------LTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLR-EM 435
+++T + +E+ K K E L+ + QL+ K+ E+
Sbjct: 1930 LAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSE---LEEEKQQLVKEKTKVESEI 1986
Query: 436 LKQYLDGI 443
K+YL+ I
Sbjct: 1987 RKEYLEKI 1994
Score = 47.0 bits (110), Expect = 4e-05
Identities = 77/367 (20%), Positives = 154/367 (41%), Gaps = 48/367 (13%)
Query: 29 EEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTV--LREVKTRELHKDIEILSQ 86
+E+ K+K++ + Q KD + +E SAL RTV L V+T E KD+EI +
Sbjct: 2011 QELLKEKQQEVKQLQKDCIRYQEKISALE--------RTVKALEFVQT-ESQKDLEITKE 2061
Query: 87 TFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMEL 146
+ V+ + LA ++ + A R N+ LQ ++ ES ++
Sbjct: 2062 NLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK-----ESVKSQM 2116
Query: 147 EALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLE 206
+ ++ E + ++H KE +Q+ A+ + + E E+ E Q + L
Sbjct: 2117 KQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLE-ETIGEIQ--------VTLN 2167
Query: 207 EKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQ 266
+K L+ ++ + K+ + +DR + + + K S I+ + ++I+
Sbjct: 2168 KKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIR 2227
Query: 267 KLQDAITISKGKI---MIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLV 323
+D ++ K ++ IH E + + +DK Q+ + KAQ V
Sbjct: 2228 LKEDNCSVLKDQLRQMSIHMEELKINISRLEHDK-----QIWESKAQTE----------V 2272
Query: 324 RLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNN 383
+L + TL+ K E + +L E + + + ++ S + + K+Q N+
Sbjct: 2273 QLQQKVCDTLQGENK-----ELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNS 2327
Query: 384 LEELTEE 390
LE+ E+
Sbjct: 2328 LEKCKEQ 2334
Score = 45.4 bits (106), Expect = 1e-04
Identities = 79/364 (21%), Positives = 145/364 (39%), Gaps = 62/364 (17%)
Query: 33 KKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQTFERVV 92
K+ E LLSQ ++ + EE N ++K N T L+ +K + + ++ +F + +
Sbjct: 2411 KELENLLSQEEEENIVLEEENKKA-VDKTNQLMET-LKTIKKENIQQKAQL--DSFVKSM 2466
Query: 93 DCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKE 152
N + D + EE++ S + DQL+ + L+E E+ L
Sbjct: 2467 SSLQNDRDRIVGDYQQLEERHL----SIILEKDQLIQEAAAENNKLKE----EIRGLRSH 2518
Query: 153 FETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLR 212
+ + I Y +D+ + DS+ + LE Q N
Sbjct: 2519 MDDLNSENAKLDAELIQYREDLNQVITIK--DSQQKQLLEVQLQQNK------------- 2563
Query: 213 LHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAI 272
LEN+ + K ++ LK +A ED + +F LQ + + SKEIE I +L +
Sbjct: 2564 -ELENK----YAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQV 2618
Query: 273 TI--SKGKIMIHSRE---------------SEDENRYIRNDKELVLVQLRKLKAQRTQAR 315
T +G + ++ + S + R ++ELV VQ K + +
Sbjct: 2619 TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAK-KVGEIE 2677
Query: 316 AASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKE 375
+K L L ++ +R + E+ ++AE+ R E+K+L + KE
Sbjct: 2678 DKLKKELKHLHHDAG----IMRNETETAEE--RVAELARDLVEMEQKLL------MVTKE 2725
Query: 376 QEGI 379
+G+
Sbjct: 2726 NKGL 2729
Score = 45.1 bits (105), Expect = 1e-04
Identities = 84/371 (22%), Positives = 159/371 (42%), Gaps = 61/371 (16%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKL-AKEEHNSALNLNKI 61
++ KM LS + Q L+ ++ L+EE K + + + L A E+H++ N+ +
Sbjct: 1729 ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEE 1788
Query: 62 NTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHL 121
TQ ++ E T E T V + +++KD S +E + ++L
Sbjct: 1789 GTQ--SIPGE--TEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDE-----INNYL 1839
Query: 122 HNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQ---HEKEIHYLQDIFMAM 178
+DQL + R++ LEE E ++ E E+ T++ Q + E+ LQ+ M
Sbjct: 1840 QQIDQL----KERIAGLEEEKQKNKE-FSQTLENEKNTLLSQISTKDGELKMLQEEVTKM 1894
Query: 179 EQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDAT- 237
N ++ + + +L S LK EEK L L N++ +L + ++ TDA
Sbjct: 1895 --NLLNQQIQEEL---SRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQI 1949
Query: 238 ---------EDRKAAFETL-----QVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHS 283
++ K L Q+ EK+ E E++ + ++K+Q A K H+
Sbjct: 1950 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNK--SHA 2007
Query: 284 RESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNA---TLKALRKIV 340
+E L++L ++ Q QK+ +R + +A T+KAL +
Sbjct: 2008 KE------------------LQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQ 2049
Query: 341 DKGEKILKLAE 351
+ +K L++ +
Sbjct: 2050 TESQKDLEITK 2060
Score = 39.7 bits (91), Expect = 0.006
Identities = 69/380 (18%), Positives = 151/380 (39%), Gaps = 51/380 (13%)
Query: 29 EEMAKKKERLLSQFLK-DKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQT 87
EE+ + +E++ Q L+ + L H + ++ + + + ++ E ++++
Sbjct: 1337 EEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDE 1396
Query: 88 FERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELE 147
++++ K+ + L+ LSE E AL + + ++E+ E
Sbjct: 1397 LQKLISKKEEDVSYLSGQLSEKEA-----------------ALTKIQTEIIEQ------E 1433
Query: 148 ALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQ--NYIDSEYESKLEFQ--------SMW 197
L K T+ + +H++ I LQ M+Q I E +K + Q S
Sbjct: 1434 DLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRK 1493
Query: 198 NDLK-NMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSK 256
LK N +L+E+ L +E L + DV + +++ L + E+ K
Sbjct: 1494 EALKENKSLQEELSL---ARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDK 1550
Query: 257 EI-EVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQAR 315
I E+ ++ + + K+ + + DKE ++ ++ LK+ +
Sbjct: 1551 LITEMDRSLLENQSLSSSCESLKLALEG---------LTEDKEKLVKEIESLKSSKIAES 1601
Query: 316 AASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKE 375
Q+ L E L++ + ++ E+I + E R+ E++++ S K+
Sbjct: 1602 TEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ---EKQELYGKLRSTEANKK 1658
Query: 376 QEGIQKNNLEELTEELTKVM 395
+ Q E+ EE+ + M
Sbjct: 1659 ETEKQLQEAEQEMEEMKEKM 1678
Score = 34.3 bits (77), Expect = 0.26
Identities = 101/500 (20%), Positives = 193/500 (38%), Gaps = 125/500 (25%)
Query: 3 KKEKMAKTPLSDEKQLLLFQQKLLAEEEMAK-----KKERLLSQFLKDKLAKEEHNSALN 57
++++ + L + K+LL +L EEE+A KKE LS+ + ++ +++ N +
Sbjct: 990 QRKRKLQAALINRKELLQRVSRL--EEELANLKDESKKEIPLSETERGEVEEDKENKEYS 1047
Query: 58 LNKINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSE---AEEQYA 114
+ ++ + + +K K++E+ + + KDL E AEEQ+
Sbjct: 1048 EKCVTSKCQEIEIYLKQTISEKEVEL----------------QHIRKDLEEKLAAEEQFQ 1091
Query: 115 HALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDI 174
++ ++Q L + +++ LL+ + E +A+ ++ T D +
Sbjct: 1092 ALVKQ----MNQTLQDKTNQIDLLQAEIS-ENQAIIQKLITSNTDASDG--------DSV 1138
Query: 175 FMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYT 234
+ E I E W LEEK L LE E L +K Q+ L +
Sbjct: 1139 ALVKETVVISPPCTGSSEH---WKP----ELEEKI---LALEKEKEQLQKKLQEALTS-- 1186
Query: 235 DATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIR 294
RKA + Q K+ +E++ Q +LQ+ E EN I
Sbjct: 1187 -----RKAILKKAQEKERHLREELKQQKDDYNRLQEQFD-----------EQSKENENIG 1230
Query: 295 NDKELVLVQLR-----KLKAQRTQARAASQKNL------------VRLTLESN------- 330
+ + +Q+R KL + Q +S L + LESN
Sbjct: 1231 DQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPS 1290
Query: 331 --------------ATLKALRKIV--DKGEKILKLAEICRKFETEEEKVLPFYSSVLTPK 374
A +KA K + +K E LK++ + + E+V +
Sbjct: 1291 HSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQI---- 1346
Query: 375 EQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLRE 434
++G++ +L+ ++ E + E+ ++ +L+ L+H R ++ KL E
Sbjct: 1347 NKQGLEIESLKTVSHEAE------VHAESLQQKLESSQLQIAGLEHLR----ELQPKLDE 1396
Query: 435 MLKQYLDGISVSDEVLSQLN 454
+ K IS +E +S L+
Sbjct: 1397 LQKL----ISKKEEDVSYLS 1412
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,970,914
Number of Sequences: 37866
Number of extensions: 681178
Number of successful extensions: 4123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 546
Number of HSP's that attempted gapping in prelim test: 3168
Number of HSP's gapped (non-prelim): 1209
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.