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Search of human proteins with 224548936
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
(715 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 1411 0.0
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 219 5e-57
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 175 1e-43
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 163 6e-40
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 158 1e-38
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 157 2e-38
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 155 9e-38
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 155 2e-37
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 151 2e-36
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 151 2e-36
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 143 6e-34
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 141 2e-33
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 137 5e-32
gi|50083281 KIAA1853 protein [Homo sapiens] 125 1e-28
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 123 5e-28
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 123 5e-28
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 120 6e-27
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 118 2e-26
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 117 4e-26
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 116 6e-26
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 110 5e-24
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 108 1e-23
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 108 2e-23
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 108 2e-23
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 108 2e-23
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 105 1e-22
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 104 2e-22
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 104 2e-22
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 103 4e-22
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 100 5e-21
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 1411 bits (3653), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Query: 1 MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPS 60
MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPS
Sbjct: 1 MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPS 60
Query: 61 SSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSR 120
SSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSR
Sbjct: 61 SSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSR 120
Query: 121 GRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN 180
GRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN
Sbjct: 121 GRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN 180
Query: 181 RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR
Sbjct: 181 RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
Query: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHS 300
KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHS
Sbjct: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHS 300
Query: 301 RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS 360
RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS
Sbjct: 301 RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS 360
Query: 361 KERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY 420
KERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY
Sbjct: 361 KERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY 420
Query: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480
KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS
Sbjct: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480
Query: 481 KERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540
KERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN
Sbjct: 481 KERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540
Query: 541 KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN 600
KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN
Sbjct: 541 KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN 600
Query: 601 KQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTS 660
KQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTS
Sbjct: 601 KQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTS 660
Query: 661 SLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKLA 715
SLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKLA
Sbjct: 661 SLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKLA 715
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 219 bits (559), Expect = 5e-57
Identities = 224/744 (30%), Positives = 323/744 (43%), Gaps = 103/744 (13%)
Query: 17 SGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSN 76
SGSS D S S ++P +P P+ R+ S K+ T P +
Sbjct: 1441 SGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR---PRS 1497
Query: 77 RPSSRSRVRSKARTPSRVSTDTRTSKASKA---SDVRCHQRRGTHSR-----GRTPGRRG 128
R S + +K TP R + + +S K + + R G+ +P R
Sbjct: 1498 RSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERS 1557
Query: 129 -SRSSKRSPSRASTPGRIRTH-GARPGMASRVR-TPTSQQKGSRGKSYGRPRTSNRERSD 185
S SS S ++ TP R R+ G+ P + S+ R +P + GS + +PR + R +S
Sbjct: 1558 ESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSG 1617
Query: 186 SQ---------PRNLSKKSYRPPGGSGIGRSSELAVTP------------------STAK 218
S PR L ++S G G S E + + S+ +
Sbjct: 1618 SDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE 1677
Query: 219 CQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRP 278
+T + P + +S SP +RK + + SR S SP S + ++ + S P
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRR----SRSASSSPETRSRTPPRHRRSPSVSSP 1733
Query: 279 QSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKG 338
+ +SRS RR RS S RT + R R+ S +G+ RS S+
Sbjct: 1734 EPAEKSRSSRRRRSASSPRTKTTSR-------RGRSPSPKPRGL---------QRSRSRS 1777
Query: 339 KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQ 398
+ + T RR RS + S++ S+ R S SRS R GS + R +S + +
Sbjct: 1778 RREKTRTTRRRDRSGS-SQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR 1836
Query: 399 RDHSRSRSPNKARDRSRSR---SPYK---------ARDRSRSRSPNKARDCSRSR-SPYK 445
R RSR+P +R RSRSR +P+K RSRSR+P +R SRSR SP
Sbjct: 1837 RRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVS 1896
Query: 446 ----------ARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKER 495
R RSRSR+ +R SRSR+P R RSRSR+P+ R S+ +P R
Sbjct: 1897 RRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRR-RSRSRTPPVTR 1955
Query: 496 DHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEER 555
RSR+P R+ +SR+S R RSR+ R+R +SR+ R RS+SR+ R
Sbjct: 1956 RRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTR 2015
Query: 556 EHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG----------Y 605
+SR+P R R R R+P R+R +SRS R SRSR+P G
Sbjct: 2016 RRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAI 2075
Query: 606 SRPRASSKEKAHSRSRTPSKEGNHSQSRT------SSKESDPSQSTVPRSP-DWKRSPTR 658
R AS SRS TP NHS SRT SS+ S S+ ++ +P D RSP
Sbjct: 2076 RRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGM 2135
Query: 659 TSSLSQNRTPSKTSSHSPSTFPSG 682
L +RTP + + G
Sbjct: 2136 LEPLGSSRTPMSVLQQAGGSMMDG 2159
Score = 219 bits (557), Expect = 9e-57
Identities = 227/750 (30%), Positives = 346/750 (46%), Gaps = 90/750 (12%)
Query: 17 SGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSN 76
S SS P + K + K +S + ++ P +P S + +K KR+ S
Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSP--------TPKSKRKSKDKKRKRSRST 251
Query: 77 RPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTP----GRRG---- 128
P+ +SR ++ + S+ + S+++ + H T GR+P GRRG
Sbjct: 252 TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT---TALAGRSPSPASGRRGEGDA 308
Query: 129 --SRSSKRSPSRASTPGRIRTHGARP--------GMASRVRTPTSQQKGSRGKSYGRPRT 178
S S R S+P + P S R S ++ S G P
Sbjct: 309 PFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP 368
Query: 179 SNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSS 238
ER P+ L+ P + SE + T + ++P +P S++ PS
Sbjct: 369 LLAERHGGSPQPLATT---PLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
Query: 239 S-RKVKSYGQMIIPSREKSYSP---TEMSSRVKSYNQASTRS-RPQSHS--------QSR 285
KV + S + + +P E+SS S N++ R+ R +SHS +SR
Sbjct: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485
Query: 286 SP---RRSRSGSQ---KRTHSRVRSHSWKRNHS-----RARSRTRKGILSQMGRHSQSRS 334
SP +R RS S+ KR HSR RS W+R+ S R+RS R+G R SRS
Sbjct: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545
Query: 335 HSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS 394
+ + + +SR+ RRGRSH SR+P+ R S SR+ ++ R + R+ RS+S +
Sbjct: 546 RNTQR-RGRSRSARRGRSH--SRSPAT-RGRSRSRTPARRGRSRSRTPARR---RSRSRT 598
Query: 395 PNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRS 454
P ++R SRSR+P + R RSRSR+P AR RSR+RSP + R SRSRSP + RSRSR+
Sbjct: 599 PTRRR--SRSRTPAR-RGRSRSRTP--ARRRSRTRSPVRRR--SRSRSPARRSGRSRSRT 651
Query: 455 PNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ-----C 509
P + R SRSR+P + R RSRSR+P++ S+ +P++ R RSR+P + R
Sbjct: 652 PAR-RGRSRSRTPAR-RGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLV 708
Query: 510 RQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR 569
R+ RS S+ R S ER+ + S + R S R+SRS S R +
Sbjct: 709 RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK 768
Query: 570 RRWRSPSKERERRQSRSSSEERDHSRSRSP--NKQSGYSRPRASSK---EKAHSRSRTPS 624
+ R R+S S S +S++P +SG S+P+A S+ ++ S S P
Sbjct: 769 AKSR-----LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPP 823
Query: 625 KEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPS-GG 683
K+ + + SR S S P +P + S T + Q+ TP + S S P
Sbjct: 824 KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS 883
Query: 684 QTLSQDD-SQADATTSKATLPGERSSSSSS 712
+T S+ S + K++ P +S S SS
Sbjct: 884 RTPSRHSCSGSSPPRVKSSTPPRQSPSRSS 913
Score = 212 bits (540), Expect = 8e-55
Identities = 219/732 (29%), Positives = 331/732 (45%), Gaps = 90/732 (12%)
Query: 19 SSMPTADPKPPASL----KSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAP 74
+ P +P P SL S++S TP + K R S S + KS+ K+
Sbjct: 160 AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR 219
Query: 75 SNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKR 134
S S + + RS R S D + K S+++ RR S S R
Sbjct: 220 SESESKKRKHRSPTPKSKRKSKDKKR-KRSRSTTPAPKSRRAHRSTSADSASSSDTSRSR 278
Query: 135 SPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKK 194
S S A+ +TH +A R +P S ++G + P T++ +R S P +K+
Sbjct: 279 SRSAAA-----KTHTT--ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS-PETATKQ 330
Query: 195 SYRPPGGSGIGRSSELAVTPSTAKCQTPTG--------IPSKEKSDNPSPSS----SRKV 242
P + + A PS + ++ TG + ++ +P P + S++
Sbjct: 331 PSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP 390
Query: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQ----SHSQSRSPRRSRSGSQKRT 298
+ P+R++S P +S + S+ PQ S S SP + +
Sbjct: 391 VNPPSEASPTRDRS-PPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
Query: 299 HSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRN 358
H + S +N S R++ K HS + S G+S++ + T +RGRS SR
Sbjct: 450 HREISSSPTSKNRSHGRAKRDKS-------HSHTPSRRMGRSRSPA-TAKRGRSR--SRT 499
Query: 359 PSKERSHSHSRSS----SKERDHRGSSSPRKESGRSQS----GSPNKQRDHSRSRSPNKA 410
P+K R HS SRS S+ G S + GRS+S G + R RS +
Sbjct: 500 PTK-RGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR 558
Query: 411 RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKA 470
R RS SRSP R RSRSR+P + R SRSR+P AR RSRSR+P + R SRSR+P +
Sbjct: 559 RGRSHSRSP-ATRGRSRSRTPAR-RGRSRSRTP--ARRRSRSRTPTRRR--SRSRTPAR- 611
Query: 471 RDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKE 530
R RSRSR+P++ R ++ SP + R RSRSP++ +SR+ ++ R RSR+P++
Sbjct: 612 RGRSRSRTPARRRSRTR--SPVRRRS--RSRSPARRSGRSRSRTPAR-RGRSRSRTPAR- 665
Query: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR-----RRWRSPSKERERRQSR 585
R R +SR+P + RS+SR+P+ R +SR+P + R R RR RS S+ +RR
Sbjct: 666 RGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS 724
Query: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
SS ER + S + S P + RSR+ S + ++SR S + S S
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Query: 646 VPRSPDWKRSPTRTSSLS-----QNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700
P+ + P R+ S S ++RTP + S S S P K+
Sbjct: 785 CPKQKS-QTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK----------------QKS 827
Query: 701 TLPGERSSSSSS 712
P +S SSSS
Sbjct: 828 KTPSRQSHSSSS 839
Score = 190 bits (482), Expect = 5e-48
Identities = 212/666 (31%), Positives = 298/666 (44%), Gaps = 80/666 (12%)
Query: 2 SSPKRSSK---PSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMS 58
SSP +K P + SGSS P D K S + ++S + V KP + +
Sbjct: 1561 SSPDSKAKTRTPLRQRSRSGSS-PEVDSKSRLSPRRSRSGSSPE--VKDKPRAAPRAQSG 1617
Query: 59 PSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTH 118
SS K+ + + P SRS SK R PS + + S R RRG+
Sbjct: 1618 SDSSPEPKAPAPRALPRR---SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT-ARRGSR 1673
Query: 119 S------RGRTPGRRGSRSSKRSP--SRASTPGRIRTHGARPGMASRVRTPTSQQKG--- 167
S + RTP RR RSS+ SP +R + R R+ A +R RTP ++
Sbjct: 1674 SSPEPKTKSRTPPRR--RSSRSSPELTRKARLSR-RSRSASSSPETRSRTPPRHRRSPSV 1730
Query: 168 SRGKSYGRPRTSNRERSDSQPR--NLSKKSYRP-PGGSGIGRSSELAVTPSTAKCQTPTG 224
S + + R+S R RS S PR S++ P P G+ RS S ++ +
Sbjct: 1731 SSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR------SRSRREKTRT 1784
Query: 225 IPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQS 284
+++S + +S R+ +S + + R + S SR + ++S S + +S
Sbjct: 1785 TRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS--GYHSRSPARQESSRTSSRRRRGRS 1842
Query: 285 RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQS 344
R+P SR KR+ SR WKR+ SRA T R S+SR+ + +++S
Sbjct: 1843 RTPPTSR----KRSRSRTSPAPWKRSRSRASPATH--------RRSRSRTPLISRRRSRS 1890
Query: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS 404
RT R + SR S R S SR+S R S +P RS+S +P +R SRS
Sbjct: 1891 RTSPVSRRRSRSRT-SVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRR-RSRS 1948
Query: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
R+P R RSRSR+P R RSRSR+ R SRSR+ R RSRSR+ R SRS
Sbjct: 1949 RTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS 2008
Query: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRR- 523
R+ R RSRSR+P R S+ +P R RSRSP R+ +SR+ R R
Sbjct: 2009 RTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSL 2068
Query: 524 SRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQ 583
+RSP R+R S S + DRS+S +P R H SR+P + + R
Sbjct: 2069 TRSPPAIRRRSASGSSS---DRSRSATPPATRNHSGSRTPPV--------ALNSSRMSCF 2117
Query: 584 SRSSSEERDHSRSRSPN--KQSGYSRPRASSKEKA--------------HSRSRTPSKEG 627
SR S R RSP + G SR S ++A H R+ P
Sbjct: 2118 SRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPE--- 2174
Query: 628 NHSQSR 633
NH+QSR
Sbjct: 2175 NHAQSR 2180
Score = 183 bits (464), Expect = 6e-46
Identities = 199/644 (30%), Positives = 290/644 (45%), Gaps = 67/644 (10%)
Query: 57 MSPSSSKSTKSTSTKRAP---------SNRPSSRSRVRSKARTPSRVSTDTRTSKASKAS 107
M S++S+ +S++ +P SN+ S + + RTPSR + + +S K
Sbjct: 1371 MKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDG 1430
Query: 108 DVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQK- 166
R RR G +PG R + TP R G+ PGM RTP+ +
Sbjct: 1431 LPRTPSRRSRS--GSSPGLRDG---------SGTPSRHSLSGSSPGMKDIPRTPSRGRSE 1479
Query: 167 -GSRGKSYGRPRTSN-RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTG 224
S + P+T R RS S P L+ K P SE +V T +TP G
Sbjct: 1480 CDSSPEPKALPQTPRPRSRSPSSPE-LNNKCLTPQRERS---GSESSVDQKTV-ARTPLG 1534
Query: 225 IPSKEKSDNP---SPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
S+ S PS+S + +S S+ K+ +P SR + S P+
Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSR--------SGSSPEVD 1586
Query: 282 SQSR-SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKS 340
S+SR SPRRSRSGS + R+ ++ S + + + R S+S S SKG+
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
Query: 341 QNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD 400
+ + S +P K R+ SS E + + PR+ S RS K R
Sbjct: 1647 PSPEGSSSTESS---PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 401 HSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARD 460
RSRS + + + +RSR+P + R RS S + +SRS + R S R+ +R
Sbjct: 1704 SRRSRSASSSPE-TRSRTPPRHR---RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR- 1758
Query: 461 HSRSRSPN---KARDRSRSRS------PSKERDHSQLGSPSKERDHRRSRSPSKERQCRQ 511
R RSP+ + RSRSRS ++ RD S S S R +RSRS S+ + R+
Sbjct: 1759 --RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSG-SSQSTSRRRQRSRSRSRVTRRRR 1815
Query: 512 SRSSSKERDHRRSRSP--SKERQRRQSRSPNKERDRSQSR-SPSEEREHRQSRSPSKERD 568
S R R S S R+R +SR+P R RS+SR SP+ + R SP+ R
Sbjct: 1816 GGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR- 1874
Query: 569 RRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGN 628
R R R+P R R +SR+S R SRSR+ + SR RAS + SRSRTP
Sbjct: 1875 RSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRR-SRSRASPVSRRRSRSRTPPVTRR 1933
Query: 629 HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTS 672
S+SRT + T P + +RS +RT +++ R+ S+TS
Sbjct: 1934 RSRSRTPTTRRRSRSRTPPVTR--RRSRSRTPPVTRRRSRSRTS 1975
Score = 166 bits (420), Expect = 7e-41
Identities = 207/721 (28%), Positives = 323/721 (44%), Gaps = 115/721 (15%)
Query: 16 PSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPAT--SRNSVMSPSSSKSTKSTSTKRA 73
P + PT D PP S + ++ + S P+ T SR++ SP S K + + R
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452
Query: 74 PSNRPSSRSRVRSKAR-------TPSRVSTDTRTSKASK--ASDVRCHQRRGTHSRGRTP 124
S+ P+S++R +A+ TPSR +R+ +K S R +RG HSR R+P
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRG-HSRSRSP 511
Query: 125 GRRGSRSSKRSPSRASTPGRIRTHG-ARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRER 183
R SRS++R S R R+ RPG + R+ +Q++ GR R++ R R
Sbjct: 512 QWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWS---RSRNTQRR-------GRSRSARRGR 561
Query: 184 SDSQ-PRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKV 242
S S+ P + R P G RS TP+ + ++ T P++ +S + +P+
Sbjct: 562 SHSRSPATRGRSRSRTPARRGRSRSR----TPARRRSRSRT--PTRRRSRSRTPARR--- 612
Query: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRV 302
R +S +P SR TRS + S+SRSP R S+ RT +R
Sbjct: 613 ---------GRSRSRTPARRRSR--------TRSPVRRRSRSRSPARRSGRSRSRTPAR- 654
Query: 303 RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKE 362
R S R +R R R+R ++ S+SR+ ++ + +++SRTPRRGRS + S
Sbjct: 655 RGRSRSRTPAR-RGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRS---LVR 709
Query: 363 RSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKA 422
R SHSR+ + R GSSS RK R+ QR + SP + R SR ++
Sbjct: 710 RGRSHSRTPQR-RGRSGSSSERKNKSRT------SQRRSRSNSSPEMKKSRISSR---RS 759
Query: 423 RDRSRSRSPNKAR-DCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSK 481
R S RS K+R RS S + +S++P + RSRS ++ +++SR+P +
Sbjct: 760 RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR-----RSRS-GSSQPKAKSRTPPR 813
Query: 482 ERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNK 541
R S P K+ +S++PS RQS SSS +S +P ++ S N+
Sbjct: 814 -RSRSSSSPPPKQ----KSKTPS-----RQSHSSSSPHPKVKSGTPPRQGS-ITSPQANE 862
Query: 542 ERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK 601
+ Q RS E + +S + R SP + + R S SRS SP
Sbjct: 863 QSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP-----SRSSSPQP 917
Query: 602 QSGYSRPRASSKEKAHSRSRTPSKEGNHS-----QSRTSSKESDPSQSTVPR-------S 649
+ + S ++++HS S +PS S +SR+ S S+ +PR S
Sbjct: 918 K---VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSS 974
Query: 650 PDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSS 709
PD K P P ++ S S S +P + +Q + SK+ P E+S
Sbjct: 975 PDTKVKP--------ETPPRQSHSGSISPYP---KVKAQTPPGPSLSGSKSPCPQEKSKD 1023
Query: 710 S 710
S
Sbjct: 1024 S 1024
Score = 144 bits (364), Expect = 2e-34
Identities = 216/795 (27%), Positives = 311/795 (39%), Gaps = 147/795 (18%)
Query: 2 SSPKRSSKPSMS--LAPSGSSMPTADPKP-PASLKSTKSATPNRSLVPTKPATSRNSVMS 58
+SP R P S P SS ++ P P P + S++P P + R S
Sbjct: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS 456
Query: 59 PSSS-----KSTKSTSTKRAPSNR------PSSRSRVRSKARTP-------SRVSTDTRT 100
P+S ++ + S PS R P++ R RS++RTP SR R+
Sbjct: 457 PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516
Query: 101 SKASKASDVRCHQRRG---------------THSRGRTPGRRGSRSSKRSPSRASTPGRI 145
A + R QRRG T RGR+ R RS RSP +T GR
Sbjct: 517 RSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSP---ATRGR- 572
Query: 146 RTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIG 205
SR RTP RG+S R RT R RS S+ + R P G
Sbjct: 573 ----------SRSRTP-----ARRGRS--RSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615
Query: 206 RSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSR 265
RS TP+ + +T + + + +S +P+ S R +S +P R
Sbjct: 616 RSR----TPARRRSRTRSPVRRRSRSRSPARRS-------------GRSRSRTPAR-RGR 657
Query: 266 VKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQ 325
+S A R R +S + +R RSRS + R R RS + +R SR+RS R+G
Sbjct: 658 SRSRTPA-RRGRSRSRTPARRSGRSRSRTPAR-RGRSRSRTPRRGRSRSRSLVRRGRSHS 715
Query: 326 MGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER-SHSHSRSSSKERDHRGS--SS 382
+ RS S + +N+SRT +R N S K R S SRS S R S S
Sbjct: 716 RTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSL 775
Query: 383 PRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS 442
R SG S Q RSRS ++ +++SR+P + R RS S P K +S++
Sbjct: 776 RRSLSGSSPCPKQKSQTPPRRSRS-GSSQPKAKSRTPPR-RSRSSSSPPPK----QKSKT 829
Query: 443 PYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRS 502
P + S S P K + + R + ++ +S + +R SP E +SR+
Sbjct: 830 PSRQSHSSSSPHP-KVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPE---LKSRT 885
Query: 503 PSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN-------KERDRSQSRSPSEER 555
PS R S S S + S P + R S P ++R S S SPS R
Sbjct: 886 PS-----RHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSR 940
Query: 556 -----EHRQSRSPS-----KERDRRRW-RSPSKERERRQSRSSSEERDHSRSRSPNKQ-- 602
R+SRS S + R R+ S S + + + + HS S SP +
Sbjct: 941 VTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVK 1000
Query: 603 ---------SGYSRPRASSKEK--------------AHSRSRTPSKEGNHSQSRTSSKES 639
SG P K K A +S TP E S K
Sbjct: 1001 AQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQ 1060
Query: 640 DPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSK 699
+ SPD RS T + + Q+ + S + T P GG+ S+ S S+
Sbjct: 1061 SQT------SPD-HRSDTSSPEVRQSHSESPSLQSKSQTSPKGGR--SRSSSPVTELASR 1111
Query: 700 ATLPGERSSSSSSKL 714
+ + +R S+S +
Sbjct: 1112 SPIRQDRGEFSASPM 1126
Score = 131 bits (329), Expect = 2e-30
Identities = 190/727 (26%), Positives = 283/727 (38%), Gaps = 120/727 (16%)
Query: 20 SMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPS 79
S P + +P SL +S + SL + + +S P S K S N
Sbjct: 1270 SSPEVEERPAVSLTLDQSQS-QASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG 1328
Query: 80 SRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHS---RGRTPGRRGSRSSKRSP 136
S R+ + ++T + + +Q S + ++ G SS+ SP
Sbjct: 1329 SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSP 1388
Query: 137 SRASTPGRIRTHG-ARPGMASRVRTPTSQQKGSRGKSY---GRPRT-SNRERSDSQPRNL 191
G + P + + RTP+ ++ S G PRT S R RS S P L
Sbjct: 1389 DAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSP-GL 1447
Query: 192 SKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIP 251
S P S G S + P T PS+ +S+ SS + K+ Q
Sbjct: 1448 RDGSGTPSRHSLSGSSPGMKDIPRT---------PSRGRSEC---DSSPEPKALPQT--- 1492
Query: 252 SREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNH 311
R +S SP S P+ +++ +P+R RSGS+ + + +
Sbjct: 1493 PRPRSRSP----------------SSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQR 1536
Query: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
SR+ S + +S S S S+ ++RTP R RS + S
Sbjct: 1537 SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS---------------GS 1581
Query: 372 SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSP 431
S E D + SPR+ S +K R R++S + + ++ +P RSRS S
Sbjct: 1582 SPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641
Query: 432 NKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSP 491
+K R S S + S P K+R +R S + +++SR+P + R S SP
Sbjct: 1642 SKGRGPSPEGS---SSTESSPEHPPKSRT-ARRGSRSSPEPKTKSRTPPRRR--SSRSSP 1695
Query: 492 S---KERDHRRSRSPSKERQCR--------QSRSSSKERDHRRSRSP------------- 527
K R RRSRS S + R +S S S +SRS
Sbjct: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT 1755
Query: 528 -----------------SKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRR 570
S+ R RR+ + RDRS S S S R ++SRS S+ RR
Sbjct: 1756 TSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS-SQSTSRRRQRSRSRSRVTRRR 1814
Query: 571 RW------RSPSKE--------RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKA 616
R RSP+++ R R +SR+ R SRSR+ SR RAS
Sbjct: 1815 RGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR 1874
Query: 617 HSRSRTPSKEGNHSQSRTS--SKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674
SRSRTP S+SRTS S+ S+++V R R+ + S++RTP T
Sbjct: 1875 RSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRR 1934
Query: 675 SPSTFPS 681
S S P+
Sbjct: 1935 SRSRTPT 1941
Score = 130 bits (327), Expect = 4e-30
Identities = 222/820 (27%), Positives = 320/820 (39%), Gaps = 137/820 (16%)
Query: 5 KRSSKPSMSLAPS-GSSMPTADPKP--------PASLKSTKSATPNRSLVPTKPATSRNS 55
K P S S SS PT D A K + P + P
Sbjct: 1128 KSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
Query: 56 VMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRR 115
P + S K P RS S T + S +S+ + +V +
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEV---VEK 1244
Query: 116 GTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQ------QKGSR 169
G+ S + S S + + RP ++ + SQ + S
Sbjct: 1245 SEEPAGQILSHLSSELKEMSTSNFESSPEVEE---RPAVSLTLDQSQSQASLEAVEVPSM 1301
Query: 170 GKSYGRPRTS--NRERSDSQPRNLSKKS---YRPPGGSGI----GRSSELAVT---PSTA 217
S+G P S ++E S+S R S S +R G G G SSE+ P
Sbjct: 1302 ASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLN 1361
Query: 218 KCQTPTGIPSKEKSDNPSPSSSRKVK---------SYGQMI----------IPSREKSYS 258
+ +T + KE+S S SS ++ S Q I PSRE+S S
Sbjct: 1362 QLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSS 1421
Query: 259 PTEMSSRVKSYNQASTRSR----PQSHSQSRSP-RRSRSGSQKRTHSRVRSHSWKRNHSR 313
+ + S RSR P S +P R S SGS R+ S R S
Sbjct: 1422 ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS--RGRSE 1479
Query: 314 ARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWS--------RNPSKERSH 365
S L Q R +SRS S + N+ TP+R RS + S R P +RS
Sbjct: 1480 CDSSPEPKALPQTPR-PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR 1538
Query: 366 SHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDR 425
S SS+E D + S+SP++ S SP+ + +++R+P R RSRS S + +
Sbjct: 1539 S---GSSQELDVKPSASPQERS--ESDSSPDSK---AKTRTP--LRQRSRSGSSPEVDSK 1588
Query: 426 SRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDH 485
SR SP ++R S K R R++S + + ++ +P RSRS S SK R
Sbjct: 1589 SRL-SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGP 1647
Query: 486 SQLGS---------PSKERDHRR-----------SRSPSKERQCRQSRS-SSKERDHRRS 524
S GS P K R RR SR+P + R R S + K R RRS
Sbjct: 1648 SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
Query: 525 RSPSKERQRRQSRSPNKERDRS-QSRSPSEE----REHRQSRSPSKERDRRRWRSPSKER 579
RS S + R P R S S P+E+ R R + SP + RR RSPS +
Sbjct: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767
Query: 580 ---ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSK----EGNHSQ- 631
+R +SRS E+ +R R +SG S+ + ++++ SRSR + G HS+
Sbjct: 1768 RGLQRSRSRSRREKTRTTRRRD---RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
Query: 632 ------SRTSSKESDPSQSTVPRS----------PDWKRSPTRTSSLSQNRTPSKTSSHS 675
SRTSS+ T P S WKRS +R S + R+ S+T S
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
Query: 676 PSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKLA 715
S +S+ S+ S+ ++ RS S +S ++
Sbjct: 1885 RRRSRSRTSPVSRRRSR-----SRTSVTRRRSRSRASPVS 1919
Score = 129 bits (323), Expect = 1e-29
Identities = 154/539 (28%), Positives = 230/539 (42%), Gaps = 95/539 (17%)
Query: 251 PSREKSYSPTEMSSRVKSYNQASTRSRPQS----HSQSRSPRRSRSGSQKRTHSRVRSHS 306
P K YS SS +S + + + S+S SPRR R S K+ R S S
Sbjct: 165 PEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESES 224
Query: 307 WKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTP-----RRGRSHNWSRNPSK 361
KR H RS T K S+ +S K + +++S TP R RS + S
Sbjct: 225 KKRKH---RSPTPK---------SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS 272
Query: 362 ERSHSHSRSSSKERDHRGSS--SPRKESGRSQSG-SPNKQRDHSRSRSPNKARDRSRS-R 417
+ S S SRS++ + + SP SGR G +P + + ++ P+ ++
Sbjct: 273 DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPS 332
Query: 418 SPYKARDRSR--------SRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP-- 467
SPY+ +D+ + S SP ++ +P SP S+ P
Sbjct: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
Query: 468 -----NKARDRSRSRSPSKERDHSQLGS------PSKERDHRRSR--------SPSKERQ 508
+ RDRS +SP K S S P+K H S +P R+
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452
Query: 509 CRQSRSSSKERDHRR-----SRSPSKERQRRQSRSP-NKERDRSQSRSPSEEREHRQSRS 562
S +SK R H R S S + R+ +SRSP +R RS+SR+P++ R H +SRS
Sbjct: 453 ISSS-PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTK-RGHSRSRS 510
Query: 563 PSKERDR------------RRWRSPSKER--------ERRQSRSSSEERDHSRSRSPNKQ 602
P R R RR RS S +R +R+ RS S R S SRSP +
Sbjct: 511 PQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATR 570
Query: 603 SGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSS- 661
G SR R ++ + SRSRTP++ S+SRT ++ S++ R R+P R S
Sbjct: 571 -GRSRSRTPAR-RGRSRSRTPAR--RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR 626
Query: 662 -------LSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
S++R+P++ S S S P+ + S+ + A S++ P RS S S+
Sbjct: 627 TRSPVRRRSRSRSPARRSGRSRSRTPA-RRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
Score = 106 bits (264), Expect = 9e-23
Identities = 188/773 (24%), Positives = 282/773 (36%), Gaps = 103/773 (13%)
Query: 13 SLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKR 72
SL G S + D + S + + + +K TS S SSS T+ S
Sbjct: 1054 SLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSP 1113
Query: 73 APSNRPS-SRSRVRSKARTP--SRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGS 129
+R S S + +P SR +D+ + ++ + R T
Sbjct: 1114 IRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQ 1173
Query: 130 RSSKRSPSRASTPGRIRTHGARPGMA----SRVRTPTSQQKGSRGKSYGRPRTSNRERS- 184
+ SP R RP + +RTP ++ G+ + + S S
Sbjct: 1174 EDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSS 1233
Query: 185 -DSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPS----SS 239
D + + +KS P G SSEL ST+ ++ S E + P+ S S
Sbjct: 1234 QDEELMEVVEKSEEPAGQILSHLSSELKEM-STSNFES-----SPEVEERPAVSLTLDQS 1287
Query: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTH 299
+ S + +PS S+ S K + + P + SP R+ T
Sbjct: 1288 QSQASLEAVEVPSMASSWGGPHFSPEHKELSNS-----PLRENSFGSPLEFRNSGPLGTE 1342
Query: 300 SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQ---SRTPRRGRSHNWS 356
S + + + QS + S G S ++ + G S N S
Sbjct: 1343 MNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQS-TRSSGHSSSELSPDAVEKAGMSSNQS 1401
Query: 357 ----------RNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD------ 400
R PS+ERS S S K+ PR S RS+SGS RD
Sbjct: 1402 ISSPVLDAVPRTPSRERSSSASSPEMKD------GLPRTPSRRSRSGSSPGLRDGSGTPS 1455
Query: 401 -HSRS----------RSPNKARD---------------RSRSRSPYKARDRSRSRSPNKA 434
HS S R+P++ R R RSRSP ++ +P +
Sbjct: 1456 RHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRE 1515
Query: 435 RDCSRS--------RSPYKARDRSRSRSP----NKARDHSRSRSPNKARDRSRSRSPSKE 482
R S S R+P R RS S A RS S + ++++R+P ++
Sbjct: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQ 1575
Query: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
R S S E D + SP + R K R R++S S ++ +P
Sbjct: 1576 RSRS---GSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL 1632
Query: 543 RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQ 602
RS+S S S+ R S S E P RR SRSS E + SR+ P ++
Sbjct: 1633 PRRSRSGSSSKGRGPSPEGSSSTESSPEH--PPKSRTARRGSRSSPEPKTKSRT-PPRRR 1689
Query: 603 SGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSL 662
S S P + K + RSR+ S ++SRT + + P + RS R S
Sbjct: 1690 SSRSSPELTRKARLSRRSRSASSSPE-TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
Query: 663 SQNRTPSKTSSH---SPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
S RT KT+S SPS P G L + S++ ++ T +RS SS S
Sbjct: 1749 SSPRT--KTTSRRGRSPSPKPRG---LQRSRSRSRREKTRTTRRRDRSGSSQS 1796
Score = 99.8 bits (247), Expect = 8e-21
Identities = 204/846 (24%), Positives = 305/846 (36%), Gaps = 180/846 (21%)
Query: 6 RSSKPSMSLAPSGSSMPTADPK-----PPASLKSTKSATP----NRSLVPTKPAT----- 51
RS P ++ S S PT + PP + + ++S TP RS T P T
Sbjct: 1924 RSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSR 1983
Query: 52 SRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTP------SRVSTDTRTSKASK 105
SR S ++ S+S S T+R +R S +R RS++RTP SR T K S+
Sbjct: 1984 SRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR 2043
Query: 106 ASDVRCHQRRGTHSRGRTPGR-RGSRSSKRSP---------------SRASTPGRIRTH- 148
+ +RR SR RTP RG RS RSP SR++TP R H
Sbjct: 2044 SRSPLAIRRR---SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHS 2100
Query: 149 GAR-----------------------------PGMASRV---RTPTS--QQKGSRGKSYG 174
G+R PGM + RTP S QQ G
Sbjct: 2101 GSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGP 2160
Query: 175 RPRTSNRERSDSQPRNLSKKSYR-------------PPGGSGIGRSSELAVTPSTAKCQT 221
PR + +R+ S P N ++ PP S G ++ ++ P+
Sbjct: 2161 GPRIPDHQRT-SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPA------ 2213
Query: 222 PTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
P + S + + +S S M + S PT + N A +R+ +
Sbjct: 2214 PVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAV-------NLADSRTPAAAA 2266
Query: 282 SQS-RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKS 340
+ + SPR + + S + N + AR+ LS G + + + S
Sbjct: 2267 AMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSS 2326
Query: 341 QNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD 400
SRTP+ S N S +H+ + R +++ S S +P
Sbjct: 2327 ---SRTPQAPASANLVGPRS-----AHATAPVNIAGSRTAAALAPASLTSARMAPALSGA 2378
Query: 401 HSRS-RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR-SRSPNK- 457
+ S R P A +R R+ DR+RSR+P A SR S SR ++P++
Sbjct: 2379 NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS 2438
Query: 458 ----ARDHSRSRSPNKARDRSR-----------SRS----------------------PS 480
A+D RS P+ D+SR S+S P+
Sbjct: 2439 LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPA 2498
Query: 481 KERDHSQLGSPSKE---------------RDHRRSRSPSKERQCRQSRSSSKERDHRRSR 525
HS +G P ++ R S S S S SSS
Sbjct: 2499 PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS 2558
Query: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSR 585
S S P R S +P+ + R+ R P +R+ RS S S
Sbjct: 2559 SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSS-----SSS 2613
Query: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
SSS S S S + S S +SS + S S +P+K G + + +S + P
Sbjct: 2614 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGER 2673
Query: 646 VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGE 705
RSP R P + S++ + S PS PS Q +++ + + G+
Sbjct: 2674 RSRSP---RKPIDSLRDSRSLSYSPVERRRPSPQPS-------PRDQQSSSSERGSRRGQ 2723
Query: 706 RSSSSS 711
R S S
Sbjct: 2724 RGDSRS 2729
Score = 83.6 bits (205), Expect = 6e-16
Identities = 155/612 (25%), Positives = 238/612 (38%), Gaps = 58/612 (9%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPAS-------LKSTKSATPNRSLVPTKPATSRN 54
S P+ ++ ++LA + S+ TA P P S + + P SL T PA +
Sbjct: 2171 SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL-RTAPAANLA 2229
Query: 55 SVMSPSSSKSTKSTSTKRAPS-----NRPSSRSRVRSKARTPSRVSTDTRTSKASKASDV 109
S + P++S + + ++ R P+ N SR+ + A + T S + A D
Sbjct: 2230 SRI-PAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLA-DP 2287
Query: 110 RCHQRRGTHSRG-RTPGRRGSRS---SKRSPSRASTPGRIRTHGARP-----GMASRVRT 160
R + G RTP + S S P+ A+ P RT A G S T
Sbjct: 2288 RTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHAT 2347
Query: 161 PTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTP--STAK 218
GSR + P + R + S R P S R S P A+
Sbjct: 2348 APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPL-SAYERVSGRTSPPLLDRAR 2406
Query: 219 CQTPTGIPSKEKSDN---PSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR 275
+TP PS+ + + PSPSS ++ P++++ SP + +S +
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS-RCLIAQ 2465
Query: 276 SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSH 335
+ P + SQS S SG+ T S +H+ S G+ + +
Sbjct: 2466 TTPVAGSQSLS-----SGAVATTTSSAG------DHNGMLSVPAPGVPHSDVGEPPASTG 2514
Query: 336 SKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSP 395
++ S + P + R + S + S S S S SSS SSS + S
Sbjct: 2515 AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV 2574
Query: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP 455
+R S + +P +A R P A+ + RS S + + S S S S S S
Sbjct: 2575 ALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS-------SSSSSS 2627
Query: 456 NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSS 515
+ + S S S + + S S SP+K + L P+ + + P ER+ R R
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA-LPKPASPK-----KPPPGERRSRSPRKP 2681
Query: 516 SKERDHRRSRSPSKERQRRQSRSPN-KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRS 574
RS S S +RR S P+ +++ S S S + SRSPS +R RR S
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR-RRETPS 2740
Query: 575 PSKERERRQSRS 586
P R R SRS
Sbjct: 2741 PRPMR-HRSSRS 2751
Score = 77.0 bits (188), Expect = 6e-14
Identities = 171/754 (22%), Positives = 276/754 (36%), Gaps = 87/754 (11%)
Query: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS 62
+P S K S S + PA+ + ++S TP L+ + + SR S +S S
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP---LISRRRSRSRTSPVSRRRS 1900
Query: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGR 122
+S S + +R+ S R S SR RS++RTP TR S+ R SR R
Sbjct: 1901 RSRTSVTRRRSRS-RASPVSRRRSRSRTPPV----TRRRSRSRTPTTR------RRSRSR 1949
Query: 123 TPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRE 182
TP RS R+P R RT P R R+ TS R +S P T R
Sbjct: 1950 TPPVTRRRSRSRTPPVTRRRSRSRTS---PITRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2006
Query: 183 RSDSQPRNLSK-KSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
RS + P + +S PP RS + ++ ++P I + +S P + ++
Sbjct: 2007 RSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKR 2066
Query: 242 VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSR 301
+ I R S S ++ S +++T ++HS SR+P + + S+ SR
Sbjct: 2067 SLTRSPPAIRRRSASGSSSDRS-------RSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119
Query: 302 VRSHSWKRNHSRARSRTRKGILSQMG--RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNP 359
+ R+ G+L +G R S G S PR +
Sbjct: 2120 PSMSPTPLDRCRS-----PGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDH----QRT 2170
Query: 360 SKERSHSHSR--------SSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKAR 411
S +H+ SR S R S+ + SQ +P + + N A
Sbjct: 2171 SVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLAS 2230
Query: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRS----RSRSPNKARDHSRSRSP 467
+ + +R+ + A + + SR+P A + R+ A + + R+P
Sbjct: 2231 RIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTP 2290
Query: 468 NK-ARDRSRSRSPSKERDHSQLGS---PSKERDHRRSRSPSKERQCRQSRSSSKERDHRR 523
A + + +R+P+ S GS P+ SR+P S
Sbjct: 2291 TAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPV 2350
Query: 524 SRSPSKERQRRQSRSPNKER--------DRSQSRSPSEEREHRQSRSPSKERDRRRWRSP 575
+ + S+ S R + + R P E R+ DR R R+P
Sbjct: 2351 NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP 2410
Query: 576 SKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTS 635
QSR +SE R+ SP+ + G + P S A + R+P QSR
Sbjct: 2411 PSAPS--QSRMTSE-----RAPSPSSRMGQA-PSQSLLPPAQDQPRSPVPSAFSDQSRCL 2462
Query: 636 SKESDPSQSTVPRSPDWKRSPTRTSSLSQNR-----------------TPSKTSSHSPST 678
++ P + S T TSS + P+ T + PS
Sbjct: 2463 IAQTTPVAGSQSLSSG--AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA 2520
Query: 679 FPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
+ + S + +++S ++ SSSSSS
Sbjct: 2521 LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554
Score = 62.4 bits (150), Expect = 1e-09
Identities = 82/331 (24%), Positives = 129/331 (38%), Gaps = 67/331 (20%)
Query: 447 RDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKE 506
++ + + P H + K +R R+ + + S +R R ++ P+ E
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISD-SYVDGSSFDPQRRAREAKQPAPE 166
Query: 507 RQ-----CRQSRSSSKERDHRRSRSPSKERQRR-QSRSPNKERDRS------QSRSPSEE 554
R+S SS ++ + K+R RR +S SP +ER +S +S S S++
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
Query: 555 REHR----QSRSPSKERDRRRWRS-----PSKERERRQSRSSSEERDHSRS--------- 596
R+HR +S+ SK++ R+R RS S+ R S S+ D SRS
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT 286
Query: 597 -------RSPNKQSG--------YSRP------RASSKEKAHSRSRTPSKEGNHSQSRTS 635
RSP+ SG +S P R SS E A + +P ++ + + S
Sbjct: 287 HTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKS 346
Query: 636 SKESDPS---QSTVPRSP----------DWKRSPTRTSSLSQN--RTPSKTSSHSPSTFP 680
+ PS ST P P P T+ LSQ PS+ S + P
Sbjct: 347 ATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPP 406
Query: 681 SGGQTLSQDDSQADATTSKATLPGERSSSSS 711
+ L Q S + S R +SSS
Sbjct: 407 KSPEKLPQSSSSESSPPSPQPTKVSRHASSS 437
Score = 39.3 bits (90), Expect = 0.013
Identities = 48/184 (26%), Positives = 83/184 (45%), Gaps = 52/184 (28%)
Query: 530 ERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSE 589
+R+ R+++ P E + S RE SRSP+ ++ +++ + K+R RR S SSS
Sbjct: 154 QRRAREAKQPAPEPPKPYSLV----RESSSSRSPTPKQKKKKKK---KDRGRR-SESSSP 205
Query: 590 ERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRS 649
R+ +S K R + SK++ H RS TP S+ ++ K+ S+ST P +
Sbjct: 206 RRERKKSSKKKKH----RSESESKKRKH-RSPTPK-----SKRKSKDKKRKRSRSTTP-A 254
Query: 650 PDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSS 709
P +R+ TS+ DS + + TS++ RS S
Sbjct: 255 PKSRRAHRSTSA----------------------------DSASSSDTSRS-----RSRS 281
Query: 710 SSSK 713
+++K
Sbjct: 282 AAAK 285
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 175 bits (444), Expect = 1e-43
Identities = 124/335 (37%), Positives = 179/335 (53%), Gaps = 42/335 (12%)
Query: 263 SSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI 322
S R +SY+++ + SR +S S+ RSRSGS K +HS+ RS S + SR++SR+R
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 323 LSQMGRH---------SQSRSHSKGKSQNQSRTPRRGRSHN-------WSRNPSKERSHS 366
S+ + S+SRSHS GKS+++S+ + N SR+PS+ +S S
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298
Query: 367 HSRSSSKER----DHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKA 422
SRS S+ER + RGS S GRSQ S + R SRS+ +++R RSRS+S K
Sbjct: 299 KSRSRSQERRVEEEKRGSVS----RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
Query: 423 RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR---DRSRSRSP 479
+ R RSR +++R SRS+S RSR RD S K + DRS+SRSP
Sbjct: 355 KGRKRSREESRSRSRSRSKS-------ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 480 SKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP 539
S+ S SKER+H +S S +E + + + + RSRS SK + S S
Sbjct: 408 SR--------SVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESR 459
Query: 540 NKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRS 574
++ + S++RS S+ R SRSPS+ R R RS
Sbjct: 460 SRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 175 bits (443), Expect = 2e-43
Identities = 125/355 (35%), Positives = 192/355 (54%), Gaps = 36/355 (10%)
Query: 288 RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTP 347
R+ R K R RS+S R+HSR+RSR+R R S+SRS S S ++SR+
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHS------RKSRSRSGSSKSSHSKSRS- 220
Query: 348 RRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSP 407
RS + SR+ SK RS S SRS SK+ R SP KE RS+S S K R S+ ++
Sbjct: 221 ---RSRSGSRSRSKSRSRSQSRSRSKKEKSR---SPSKEKSRSRSHSAGKSRSKSKDQAE 274
Query: 408 NKARD-----RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHS 462
K ++ + +SRSP + + +S+SRS ++ R + +R RS+ +S ++R S
Sbjct: 275 EKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS 334
Query: 463 RSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR 522
RS+ +++R RSRS+S K + + S+E RSRS SK +SR +RD +
Sbjct: 335 RSKGGSRSRSRSRSKSKDKRKGRKR----SREESRSRSRSRSKS---ERSRKRGSKRDSK 387
Query: 523 RSRSPSKERQ---RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKER 579
S K+++ R QSRSP SRS S+EREH +S S +E + + +
Sbjct: 388 AGSSKKKKKEDTDRSQSRSP--------SRSVSKEREHAKSESSQREGRGESENAGTNQE 439
Query: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRT 634
R +SRS+S+ + + S S ++ S+ R+ SK ++ S SR+PS+ + S SR+
Sbjct: 440 TRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 165 bits (418), Expect = 1e-40
Identities = 114/322 (35%), Positives = 164/322 (50%), Gaps = 16/322 (4%)
Query: 328 RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH-RGSSSPRKE 386
R S SRS S +S+++SR R+ RS + S S +S S SRS S+ R R S R
Sbjct: 182 RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSR 241
Query: 387 SGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKA 446
S + +S SP+K++ SRS S K+R +S+ ++ K ++ P K+R SR +S K+
Sbjct: 242 SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP-KSRSPSRHKSKSKS 300
Query: 447 RDRSRSR--SPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
R RS+ R K SR RS K+ +SRSRS SK S+ S SK +D R+ R S
Sbjct: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS 360
Query: 505 KERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPS 564
+E +SRS SK R+ S + + ++ DRSQSRSPS RS S
Sbjct: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS--------RSVS 412
Query: 565 KERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQS----GYSRPRASSKEKAHSRS 620
KER+ + S +E + + + SRSRS +K SR R+ S K SRS
Sbjct: 413 KEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRS 472
Query: 621 RTPSKEGNHSQSRTSSKESDPS 642
++ S+ + S SR+ S+ S
Sbjct: 473 KSRSRSASRSPSRSRSRSHSRS 494
Score = 149 bits (377), Expect = 7e-36
Identities = 114/340 (33%), Positives = 175/340 (51%), Gaps = 37/340 (10%)
Query: 383 PRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS 442
P RS S S + R SRSR K+R RS S ++ RSRSRS +++R SRSRS
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 443 PYKARDRS-RSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501
++R + +SRSP+K + SRS S K+R +S+ ++ K +++ +G P +SR
Sbjct: 237 QSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP-------KSR 289
Query: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561
SPS R +S SK R R Q R +E+ S SR S+E+ RQSR
Sbjct: 290 SPS------------------RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
Query: 562 SPSKER--DRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSR 619
S S+ + R R RS SK +++R+ R S E SRSRS +K S SR R S ++
Sbjct: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSK-SERSRKRGSKRDSKAGS 390
Query: 620 SRTPSKEG-----NHSQSRTSSKESDPSQSTVPRSP---DWKRSPTRTSSLSQNRTPSKT 671
S+ KE + S SR+ SKE + ++S + + + + T + S++R+ SK+
Sbjct: 391 SKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKS 450
Query: 672 SSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
+ PS S ++ S+ S++ + + A+ RS S S
Sbjct: 451 KPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
Score = 139 bits (350), Expect = 9e-33
Identities = 113/368 (30%), Positives = 187/368 (50%), Gaps = 52/368 (14%)
Query: 75 SNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKR 134
S R S SR RS +R+ SR S+ S+ S R + +HS+ R+ R GSRS +
Sbjct: 179 SRRRRSYSRSRSHSRSRSR-------SRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
Query: 135 SPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKK 194
S SR+ + R + + R+P+ ++ SR S G+ R+ ++++++ + +N
Sbjct: 232 SRSRSQSRSRSKKE--------KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQN---- 279
Query: 195 SYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSRE 254
+G+ K ++P+ SK KS S S R+V+ E
Sbjct: 280 ------NDNVGKP----------KSRSPSRHKSKSKSR--SRSQERRVEE---------E 312
Query: 255 KSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRA 314
K S + S+ KS Q+ +RSR + S+SRS RSRS S+ + R RS R+ SR+
Sbjct: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS--RSRSKSKDKRKGRKRSREESRSRSRS 370
Query: 315 RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE 374
RS++ + R S++ S K K ++ R+ +S + SR+ SKER H+ S SS +E
Sbjct: 371 RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS----QSRSPSRSVSKEREHAKSESSQRE 426
Query: 375 RDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA 434
++ + RS+S S +K + + S S ++++ S++RS K+R RS SRSP+++
Sbjct: 427 GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS 486
Query: 435 RDCSRSRS 442
R S SRS
Sbjct: 487 RSRSHSRS 494
Score = 138 bits (347), Expect = 2e-32
Identities = 111/325 (34%), Positives = 175/325 (53%), Gaps = 44/325 (13%)
Query: 175 RPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP 234
R R+ +R RS S+ R+ S+ S + SG +SS S ++ ++ +G S+ KS +
Sbjct: 181 RRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSH-----SKSRSRSRSGSRSRSKSRSR 235
Query: 235 SPSSSRKVKSYGQMIIPSREKSYSPTEMS--SRVKSYNQASTRSRPQSH---SQSRSPRR 289
S S SR K + PS+EKS S + + SR KS +QA + + + +SRSP R
Sbjct: 236 SQSRSRSKKEKSRS--PSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 290 SRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRR 349
+S S+ R+ S+ R ++ S +R R+++ L R S+SRS SKG S+++SR+ +
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSL----RQSRSRSRSKGGSRSRSRSRSK 349
Query: 350 GRSHNWSRNPSKERSHSHSRSSSK---------ERDHRGSSSPRK---ESGRSQSGSPN- 396
+ R S+E S S SRS SK +RD + SS +K ++ RSQS SP+
Sbjct: 350 SKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSR 409
Query: 397 ---KQRDHSRSRSPNKA------------RDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441
K+R+H++S S + RSRSRS K++ S S ++++ S++R
Sbjct: 410 SVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTR 469
Query: 442 SPYKARDRSRSRSPNKARDHSRSRS 466
S K+R RS SRSP+++R S SRS
Sbjct: 470 SRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 127 bits (318), Expect = 5e-29
Identities = 92/290 (31%), Positives = 149/290 (51%), Gaps = 19/290 (6%)
Query: 438 SRSRSPYKARDRSRSRSPNKARDHSRSRS------PNKARDRSRSRSPSKERDHSQLGSP 491
SR R Y +R RS SRS +++R +SRS + ++ RSRSRS S+ R S+ S
Sbjct: 179 SRRRRSY-SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 492 SKERDHR-RSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQ-----RRQSRSPNKERDR 545
S+ R + +SRSPSKE+ +S S+ K R + ++ K + + +SRSP++ + +
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSK 297
Query: 546 SQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGY 605
S+SRS S+ER + + S R R + +S + R R +S+ S R SRS+S +K+ G
Sbjct: 298 SKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGR 357
Query: 606 SRPRASSKEKAHSRSRT--PSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLS 663
R R S+ ++ SRS++ K G+ S+ S + + T RSP+R+ S
Sbjct: 358 KRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDT---DRSQSRSPSRSVSKE 414
Query: 664 QNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATT-SKATLPGERSSSSSS 712
+ S++S T + S++ + + SK LP E S S S
Sbjct: 415 REHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS 464
Score = 94.0 bits (232), Expect = 4e-19
Identities = 100/389 (25%), Positives = 177/389 (45%), Gaps = 65/389 (16%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
S KR+ + +G + + KP + + + S + + S ++ SR S S
Sbjct: 151 SDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS 210
Query: 62 SKSTKSTSTKRAPS---NRPSSRSRVRS-------KARTPSRVSTDTRTSKA----SKAS 107
SKS+ S S R+ S +R SRSR +S K+R+PS+ + +R+ A SK+
Sbjct: 211 SKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSK 270
Query: 108 DVRCHQRRGTHSRG----RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRT--P 161
D + + + G R+P R S+S RS S+ R + G SR R+
Sbjct: 271 DQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER-----RVEEEKRGSVSRGRSQEK 325
Query: 162 TSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQT 221
+ +Q SR +S G R+ +R RS S+ + +K RS E + + S ++ ++
Sbjct: 326 SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK-----------RSREESRSRSRSRSKS 374
Query: 222 PTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
K D+ + SS +K K E + R +S + + + S+ + H
Sbjct: 375 ERSRKRGSKRDSKAGSSKKKKK-----------------EDTDRSQSRSPSRSVSKEREH 417
Query: 282 SQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQ 341
++S S +R G + + + S SR+ S+++ + S+ S+S S ++ +S+
Sbjct: 418 AKSESSQREGRGESENAGTNQETRS----RSRSNSKSKPNLPSESRSRSKSASKTRSRSK 473
Query: 342 NQSRTPRRGRSHNWSRNPSKERSHSHSRS 370
++SR+ SR+PS+ RS SHSRS
Sbjct: 474 SRSRSA--------SRSPSRSRSRSHSRS 494
Score = 92.0 bits (227), Expect = 2e-18
Identities = 77/246 (31%), Positives = 122/246 (49%), Gaps = 31/246 (12%)
Query: 494 ERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE----RDRSQSR 549
E + R+ R + R+ RS S+ R H RSRS S+ ++ +SRS + + + RS+SR
Sbjct: 164 EVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSR 223
Query: 550 SPSEEREHRQSRSPSKERDRR-RWRSPSKERERRQSRSSSEERDHS-------------- 594
S S R +SRS S+ R ++ + RSPSKE+ R +S S+ + R S
Sbjct: 224 SGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 595 ---RSRSPNKQSGYSRPRASS------KEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
+SRSP++ S+ R+ S +EK S SR S+E + QSR+ S+ S+S
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS- 342
Query: 646 VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGE 705
RS +S + ++R S++ S S S + S+ DS+A ++ K +
Sbjct: 343 --RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
Query: 706 RSSSSS 711
RS S S
Sbjct: 401 RSQSRS 406
Score = 54.7 bits (130), Expect = 3e-07
Identities = 44/128 (34%), Positives = 65/128 (50%), Gaps = 14/128 (10%)
Query: 587 SSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTV 646
S R +SRSRS +SR R+ S+ SRSR+ S + +HS+SR+ S+ S
Sbjct: 179 SRRRRSYSRSRS------HSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS---- 228
Query: 647 PRSPDWKRSPTRT-SSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGE 705
RS RS +R+ S ++R+PSK S S S S G++ S+ QA+ G+
Sbjct: 229 -RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRS--HSAGKSRSKSKDQAEEKIQNNDNVGK 285
Query: 706 RSSSSSSK 713
S S S+
Sbjct: 286 PKSRSPSR 293
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 163 bits (412), Expect = 6e-40
Identities = 159/597 (26%), Positives = 258/597 (43%), Gaps = 60/597 (10%)
Query: 99 RTSKASKA-SDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASR 157
+T ASK ++VR + + R S S +S+ + ++ S
Sbjct: 158 KTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSS 217
Query: 158 VRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTP-ST 216
+++K + K R + S + + + + R SKKS S + L P ST
Sbjct: 218 DSESATEEKSKKRKKKHR-KNSRKHKKEKKKRKKSKKS-----ASSESEAENLEAQPQST 271
Query: 217 AKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRS 276
+ + IP SP + + + + RE+ +S+ SY + +
Sbjct: 272 VRPEEIPPIPENRFLMRKSPPKADEKERKNR----ERERERECNPPNSQPASYQRRLLVT 327
Query: 277 RPQSHSQSRSPRRSRSGSQKRTHSRVRSHS----WKRNHSRAR-------SRTRKGILSQ 325
R + R PRR R+ S+ R+ R R W++ RA+ R KG S+
Sbjct: 328 RSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSE 387
Query: 326 MGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK 385
+ +++ S + + + T R S + +R KE+ +S+SKERD R +S
Sbjct: 388 LNEIKENQ-RSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSE--- 443
Query: 386 ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYK 445
+K ++ + R+ +K+R +S+ +S K RD +R+ K R RS K
Sbjct: 444 --------KDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEK-----RMRSRSK 490
Query: 446 ARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRS----- 500
RD + K D +K +D+ RSRS K + QL S S E DH +S
Sbjct: 491 GRDHENVKEKEKQSD-------SKGKDQERSRSKEKSK---QLESKSNEHDHSKSKEKDR 540
Query: 501 RSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH--- 557
R+ S+ R+C ++ R RS S++R RR RS +RDRS+S+ RE
Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRV-RSRTHDRDRSRSKEYHRYREQEYR 599
Query: 558 RQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAH 617
R+ RS S+ER RS SK+R RR+ S S ER+ S+SR+ +K + KE +
Sbjct: 600 RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSE 659
Query: 618 SRSRTPSKEGNHSQSRTS-SKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSS 673
S R SK +H+ S S K++D QS + + SS+ +N+ K S
Sbjct: 660 SEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRS 716
Score = 155 bits (393), Expect = 9e-38
Identities = 150/593 (25%), Positives = 253/593 (42%), Gaps = 47/593 (7%)
Query: 66 KSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPG 125
K KR S+ SS S S + + S+ S+D+ S++ A++ + +R+ H +
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSES--ATEEKSKKRKKKHRKNSRKH 241
Query: 126 RRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRT--PTSQQKGSRGKSYGRPRTSNRER 183
++ + K+S AS+ A+P R P + + KS P+ +ER
Sbjct: 242 KKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKS--PPKADEKER 299
Query: 184 SDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVK 243
+ + ++ PP L VT S K I + +PS SR
Sbjct: 300 KNRERER--ERECNPPNSQPASYQRRLLVTRSGRK------IKGRGPRRYRTPSRSRSRD 351
Query: 244 SYGQMIIPSREKSYSPTEMSSRVKS---YNQASTRSRPQSHSQSRSPRRSRSGSQKRT-H 299
+ + P + RV S + + + RSP R + +K T H
Sbjct: 352 RFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKE--RKITDH 409
Query: 300 SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNP 359
V ++N + + K + S K K++ + R + RS + ++
Sbjct: 410 RNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSK 469
Query: 360 SKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARD---RSRS 416
SKER H+R+ K R + + S +K +D RSRS K++ +S
Sbjct: 470 SKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNE 529
Query: 417 RSPYKARDRSRSRSPNKARDC--SRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRS 474
K++++ R R+ +++R+C ++ + Y +R R RSRS +++R R RS RDRS
Sbjct: 530 HDHSKSKEKDR-RAQSRSRECDITKGKHSYNSRTRERSRSRDRSR---RVRSRTHDRDRS 585
Query: 475 RSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRR 534
RS+ + R+ + RR RS S+ER+ RS SK+R RR S S ER+
Sbjct: 586 RSKEYHRYRE---------QEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREES 636
Query: 535 QSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRW-RSPSKERERRQS-----RSSS 588
QSR+ +K R++ S +E + R SK RD S K+ +R QS + SS
Sbjct: 637 QSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSS 696
Query: 589 EERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDP 641
++ + S NK+ R SS EK + +S+ + H +++ ES P
Sbjct: 697 QDNELKSSMLKNKEDEKIR---SSVEKENQKSKGQENDHVHEKNKKFDHESSP 746
Score = 93.6 bits (231), Expect = 6e-19
Identities = 120/493 (24%), Positives = 198/493 (40%), Gaps = 65/493 (13%)
Query: 21 MPTADPKPPASLKSTKSATPNRSLVP--TKPATSRNSVMSPSSSKSTKSTSTKRAPS-NR 77
M + PK + + R P ++PA+ + ++ S + K +R + +R
Sbjct: 287 MRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSR 346
Query: 78 PSSRSRVRSKARTPS-----------RVSTDTRTSKASKA----------SDVRCHQRRG 116
SR R R P RVS+ R K K+ S VR +R+
Sbjct: 347 SRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKI 406
Query: 117 THSRG--RTPGRRGSRSSKRSPSRASTPGR-IRTHGARPGMASRVRTPTSQQKGSRGKSY 173
T R +P R+ + K ++++ R IR + + + + ++ S+ +S
Sbjct: 407 TDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKD---DKYKNKVKKRAKSKSRSK 463
Query: 174 GRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDN 233
+ ++ ++ER RN K+ G E S +K + SKEKS
Sbjct: 464 SKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKE-KQSDSKGKDQERSRSKEKSKQ 522
Query: 234 PSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSG 293
S+ S + + +++ SYN +R+R +S S+ RS RR RS
Sbjct: 523 LESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYN---SRTRERSRSRDRS-RRVRS- 577
Query: 294 SQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSH 353
RTH R RS S + + R + R+G +SRS + +SR+ R R
Sbjct: 578 ---RTHDRDRSRSKEYHRYREQEYRRRG---------RSRSRERRTPPGRSRSKDRRRRR 625
Query: 354 NWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDR 413
SR S ER S SR+ K R+ SS RKE+ S+ +K RDH+ S + ++ +
Sbjct: 626 RDSR--SSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNN-SREKKA 682
Query: 414 SRSRSPYK-----ARDRSRSRSPNKARDCSRSRSPY-------KARDRSRSRSPNKARDH 461
R +SP+ ++D S K ++ + RS K ++ NK DH
Sbjct: 683 DRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDH 742
Query: 462 SRSRSPNKARDRS 474
S P D+S
Sbjct: 743 ESS--PGTDEDKS 753
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/249 (22%), Positives = 92/249 (36%), Gaps = 23/249 (9%)
Query: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRVRSKAR----TPSRVSTDTRTSKASKASDVRCHQ 113
S SK +S S + S R +S++R T + S ++RT + S++ D
Sbjct: 516 SKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRV 575
Query: 114 RRGTHSRGRTPGRR---------GSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQ 164
R TH R R+ + R RS R + PGR R+ R R R +
Sbjct: 576 RSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRR-----RRRRDSRS 630
Query: 165 QKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTG 224
+ +S + + N+E S + S+ R S SS + + Q+P
Sbjct: 631 SEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFS 690
Query: 225 IPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQS 284
+ DN SS K K + I S EK S+ + + +++ H S
Sbjct: 691 KIKQSSQDNELKSSMLKNKE-DEKIRSSVEKE----NQKSKGQENDHVHEKNKKFDHESS 745
Query: 285 RSPRRSRSG 293
+SG
Sbjct: 746 PGTDEDKSG 754
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 158 bits (400), Expect = 1e-38
Identities = 198/783 (25%), Positives = 290/783 (37%), Gaps = 122/783 (15%)
Query: 8 SKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNR---SLVPTKPATSRNSVMSPSSSK- 63
S PS S AP + P ++ TK+ P + V P + S + +K
Sbjct: 1219 SGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKRAKV 1278
Query: 64 STKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRT 123
TK TS + P R + R R K T++RT+ S + ++ H RR +T
Sbjct: 1279 RTKKTSDSKYPMKRITKRLRKHRK------FYTNSRTTIESPSRELAAHLRRKRIGATQT 1332
Query: 124 PGRRGSRSSKRSPSRASTP------------------------GRIRTHGARPGM----- 154
+ S KR P + S P GR G RP
Sbjct: 1333 ----STASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASK 1388
Query: 155 -------ASRVRTPTSQQKGSRGKSYGRPRTSNRERSD------------SQPRNLSKKS 195
A P+S ++ R P S ++ D QPR
Sbjct: 1389 NYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQ 1448
Query: 196 YRP---PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPS 252
RP P + S+ + TA P K+ SSSR K++ + S
Sbjct: 1449 PRPLRLPKPT----DSQSGIAFQTASVGQPLRTVQKD-------SSSRSKKNFYRNETSS 1497
Query: 253 REKSYSPTEMSSRVKSYNQASTRSRPQ-----------SHSQSRSPRRSRSGSQKRTHSR 301
+E T +RV++ + S + +H + P R + + R
Sbjct: 1498 QESKNLSTP-GTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSER 1556
Query: 302 VRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSK 361
R + RNH R+++ L + RSH +N S R +W R+PS+
Sbjct: 1557 TRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSER----SW-RSPSQ 1611
Query: 362 ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS----RSPNKARDRSRSR 417
S S RG SP + S R P+++R HS S RSP++ RS S
Sbjct: 1612 RNHCSPPERSCHSLSERGLHSPSQRSHRG----PSQRRHHSPSERSHRSPSERSHRSSSE 1667
Query: 418 SPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSR 477
+++ + R P++ CS S +++ + R P++ R HS S+ +++ R R
Sbjct: 1668 RRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHR 1727
Query: 478 SPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR 537
SPS+ HS RR SPS+ C S S RR RSPS+ R S
Sbjct: 1728 SPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSE 1787
Query: 538 SPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSR 597
+ SPSE R H R RSPS+ R R S S R RS
Sbjct: 1788 KSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHR-SFERSHRRISERSH 1846
Query: 598 SPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPT 657
SP+++S S SR + G+ S +T S+ S RSP R
Sbjct: 1847 SPSEKSHLS-------PLERSRCSPSERRGHSSSGKTCHSPSERSH----RSPSGMRQ-G 1894
Query: 658 RTSSLSQNRTPSKTSSHSPSTF----PSGGQTLSQDDSQADATTS---KATLPGERSSSS 710
RTS S +R+ + + HSPS PSG S + + K + PGER S S
Sbjct: 1895 RTSERS-HRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHS 1953
Query: 711 SSK 713
S+
Sbjct: 1954 LSR 1956
Score = 119 bits (297), Expect = 1e-26
Identities = 175/612 (28%), Positives = 246/612 (40%), Gaps = 62/612 (10%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
SS KR + + L P+GS++ D +++ + P R+ +P R + S
Sbjct: 1403 SSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAY-SFQPRPLRLPKPTDSQ 1461
Query: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
S T++ P S RSK + R T ++ SK R +RG
Sbjct: 1462 SGIAFQTASVGQPLRTVQKDSSSRSK-KNFYRNETSSQESKNLSTPGTR------VQARG 1514
Query: 122 RT-PGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN 180
R PG R+ R T + H P R RTP + +R R S
Sbjct: 1515 RILPGSPVKRTWHRHLKDKLTH---KEHN-HPSFY-RERTPRGPSERTRHNPSWRNHRSP 1569
Query: 181 RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
ERS Q +L ++ + P S S + +PS ++P S+ +P S
Sbjct: 1570 SERS--QRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSP----SQRNHCSPPERSCH 1623
Query: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHS 300
+ G + PS+ P++ R S ++ S RS + +S S RR RS SQ R+H
Sbjct: 1624 SLSERG-LHSPSQRSHRGPSQR--RHHSPSERSHRSPSERSHRSSSERRHRSPSQ-RSHR 1679
Query: 301 --RVRSHSW--KRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWS 356
RSH +R H R+ +G S+ R HS K + R+P R RSH
Sbjct: 1680 GPSERSHCSPSERRHRSPSQRSHRG-------PSERRHHSPSKRSH--RSPAR-RSH--- 1726
Query: 357 RNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRS 416
R+PS+ HS S S R SP + S S S + R RSP++ R S S
Sbjct: 1727 RSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPS 1786
Query: 417 -RSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
+S + +RS + R RS + +RS RSP++ R H RS + R R
Sbjct: 1787 EKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSH-RSPSERRSH-RSFERSHRRISER 1844
Query: 476 SRSPSKERDHSQLG----SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKER 531
S SPS++ S L SPS+ R H S + C S ER H RSPS R
Sbjct: 1845 SHSPSEKSHLSPLERSRCSPSERRGH-----SSSGKTCH----SPSERSH---RSPSGMR 1892
Query: 532 QRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEER 591
Q R S ++ SPSE R R S R RSP KE + E
Sbjct: 1893 QGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS--FPGERP 1950
Query: 592 DHSRSRSPNKQS 603
HS SR Q+
Sbjct: 1951 SHSLSRDFKNQT 1962
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 157 bits (398), Expect = 2e-38
Identities = 191/731 (26%), Positives = 282/731 (38%), Gaps = 90/731 (12%)
Query: 3 SPKRSSKP-SMSLAPSGSSMPTADPKPPASLK--STKSATPNRSLVPTKPATSRNSVMSP 59
SP+ +K S S AP P+P +K S + AT ++ P
Sbjct: 200 SPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP 259
Query: 60 SSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHS 119
S K++K K RP SRSR +S++RT SR + TR + R + S
Sbjct: 260 SPEKNSKKEKEKE--KTRPRSRSRSKSRSRTRSRSPSHTRPRR-----------RHRSRS 306
Query: 120 RGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTS 179
R +P RR S + SP R + P R+ P R R+P +++ S G +S
Sbjct: 307 RSYSPRRRPSPRRRPSPRRRTPPRRMPP----PPRHRRSRSPVRRRRRSSASLSGSSSSS 362
Query: 180 NRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSS 239
+ RS S P+ K++ PP + R S A P +P P + +P+P S
Sbjct: 363 SSSRSRSPPKKPPKRTSSPPRKTR--RLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420
Query: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTH 299
+ + S SP S +V + R P + R S S K
Sbjct: 421 NRTRK--------SRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472
Query: 300 SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNP 359
+R R +++ QS S S S ++ P+R SH +
Sbjct: 473 MAAADSVQQRRQYRRQNQ-------------QSSSDSGSSSSSEDERPKR--SHVKNGEV 517
Query: 360 SKERSHSHSRSSSKE-RDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
+ R HS SRS+S R + +SPR RS S P ++R RSP+ A R R+
Sbjct: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRR-----RSPSPAPPPRRRRT 572
Query: 419 PYKA-RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSR 477
P R R+ S P + R SP R S S P + R+ SP R S
Sbjct: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKR-----RTASPPPPPKRRASP 627
Query: 478 SPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR 537
SP +R S P K+R ++ S + + SS R R +RSP + +R S
Sbjct: 628 SPPPKRRVSH-SPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP--QPNKRHSP 684
Query: 538 SPNKERDRSQSRSP------SEEREHRQSRSPSKERDRRRWRSPS-KERERRQSRSSSEE 590
SP ++ S P S + RQS SPS RR R+P K+ ++ S S
Sbjct: 685 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV 744
Query: 591 RDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS-TVPRS 649
R S SRS SG P A S ++ S N S + K P+ S + PR+
Sbjct: 745 RRVSSSRS---VSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
Query: 650 PDW-----KRSPTRTSSLSQNRTPSKTSSH--------------SPSTFPSGGQTLSQDD 690
D K+ + +++ K H +P+ + TL+Q++
Sbjct: 802 SDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEE 861
Query: 691 SQADATTSKAT 701
A K T
Sbjct: 862 PVAAPEPKKET 872
Score = 138 bits (348), Expect = 2e-32
Identities = 178/650 (27%), Positives = 250/650 (38%), Gaps = 112/650 (17%)
Query: 115 RGTHSRGRTPGRRGSRSSKRSPSRASTP---GRIRTHGARPGMASRVRTPTSQQKGSRGK 171
R R R+P RR SRS SP R S+P R R+H P ++ R+P+
Sbjct: 163 REKRERSRSPRRRKSRSP--SPRRRSSPVRRERKRSHSRSPRHRTKSRSPS--------- 211
Query: 172 SYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKS 231
P +E++ P S K P E T K P IP ++
Sbjct: 212 ----PAPEKKEKTPELPEP-SVKVKEPS-------VQEATSTSDILKVPKPEPIPEPKE- 258
Query: 232 DNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSR 291
PSP + K +EK T SR +S +++ TRSR SH++ R RSR
Sbjct: 259 --PSPEKNSK-----------KEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305
Query: 292 SG--SQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRR 349
S S +R S R R RT + RH +SRS + RR
Sbjct: 306 SRSYSPRRRPS-------PRRRPSPRRRTPPRRMPPPPRHRRSRSPVR----------RR 348
Query: 350 GRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD--------- 400
RS S S S SRS K+ R SS PRK S S SP ++R
Sbjct: 349 RRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP 408
Query: 401 ----HSRS-RSPNKARDRSRSRSP---------YKARDRSRSRSP-NKARDCSRSRSPYK 445
HS + + N+ R S SP +K ++ S SP K R S S
Sbjct: 409 PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEED 468
Query: 446 ARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE---RDHSQLGSPSKERDHRRSRS 502
+ + + R R ++ + D S S E R H + G + R H SRS
Sbjct: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
Query: 503 PSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS--------------QS 548
S + RQ +S + R R P R+R S +P R R+ +
Sbjct: 529 ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
Query: 549 RSPSEER-----EHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQS 603
RSPS R + R S SP +RR SP +RR S S +R S S P ++S
Sbjct: 589 RSPSPRRYSPPIQRRYSPSPP---PKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRS 645
Query: 604 G-YSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSL 662
++ R+ S H + +PS+ ++S +K PS PR+P SP
Sbjct: 646 SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPR--PRAPQTSSSPPPVRR- 702
Query: 663 SQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
+ +P + S SPST P + + + + S + R SSS S
Sbjct: 703 GASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRS 752
Score = 128 bits (321), Expect = 2e-29
Identities = 149/573 (26%), Positives = 232/573 (40%), Gaps = 50/573 (8%)
Query: 164 QQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPT 223
+ K R K RERS S PR +S P RSS + + ++P
Sbjct: 149 EDKDKRDKEEKESSREKRERSRS-PRRRKSRSPSPRR-----RSSPVRRERKRSHSRSPR 202
Query: 224 GIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQ 283
+K +S +P+P K + + +E S +S + + P+ S
Sbjct: 203 H-RTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSP 261
Query: 284 SRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQ 343
++ ++ + + R SR RS S R SR+ S TR + S+SRS+S + +
Sbjct: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRP----RRRHRSRSRSYSPRRRPSP 317
Query: 344 SRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSR 403
R P R R P R H RS S R R SS+ S S S S R
Sbjct: 318 RRRPSPRRRTPPRRMPPPPR---HRRSRSPVRRRRRSSASLSGSSSSSSSS--------R 366
Query: 404 SRSPNKARDRSRSRSPYKARDRSRSRSP--NKARDCSRSRSPYKARDRSRSRSPNKARDH 461
SRSP K + S P K R S S SP + R + P K R + N+ R
Sbjct: 367 SRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKS 426
Query: 462 SRSRSP---------NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQS 512
S SP +K ++ S SP+ + +L +++ + + + S +++ +
Sbjct: 427 RVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYR 486
Query: 513 RSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH--RQSRSPSKERDRR 570
R + + S S S++ + ++S N E R + SPS R+ + + R RR
Sbjct: 487 RQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRR 546
Query: 571 RWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR-TPSKEGNH 629
R RSPS RR+ RS S R R+P P + ++ S R +P + +
Sbjct: 547 R-RSPSPPPTRRR-RSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY 604
Query: 630 SQS-----RTSSKESDPSQSTVPRSPDWKR---SPT---RTSSLSQNRTPSKTSSHSPST 678
S S RT+S P + P P +R SP R+S +++ R+PS +S H +
Sbjct: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS 664
Query: 679 FPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
PS T Q + S + P +SSS
Sbjct: 665 SPS-RSTREARSPQPNKRHSPSPRPRAPQTSSS 696
Score = 113 bits (283), Expect = 5e-25
Identities = 120/399 (30%), Positives = 172/399 (43%), Gaps = 71/399 (17%)
Query: 339 KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSP-RKESGRSQSGSPNK 397
K Q++ + +R + S +ERS S R S+ R SSP R+E RS S SP
Sbjct: 145 KKQDEDKD-KRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSP-- 201
Query: 398 QRDHSRSRSPNKARDRSRSRSP------YKARDRS--------------------RSRSP 431
R ++SRSP+ A ++ + ++P K ++ S + P
Sbjct: 202 -RHRTKSRSPSPAPEK-KEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP 259
Query: 432 NKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPN----KARDRSRSRSPSKERDHSQ 487
+ ++ + + K R RSRSRS K+R +RSRSP+ + R RSRSRS S R S
Sbjct: 260 SPEKNSKKEKEKEKTRPRSRSRS--KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP 317
Query: 488 LGSPSKER-----------DHRRSRSPSKERQCRQSRS---SSKERDHRRSRSPSKERQR 533
PS R HRRSRSP + R+ R S S SS RSRSP K+ +
Sbjct: 318 RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR-RSSASLSGSSSSSSSSRSRSPPKKPPK 376
Query: 534 RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQS-------RS 586
R S P K R S S SP R HR S + R +P + R+S R+
Sbjct: 377 RTSSPPRKTRRLSPSASP-PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
Query: 587 SSEERDHSRSRSPNKQSGYSRPR-----ASSKEKAHSRSRTPSKEGNHS---QSRTSSKE 638
S + H + S +PR S ++K + S + Q++ SS +
Sbjct: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
Query: 639 SDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPS 677
S S S+ P KRS + + + R S + S SPS
Sbjct: 496 SGSSSSSEDERP--KRSHVKNGEVGRRRRHSPSRSASPS 532
Score = 102 bits (254), Expect = 1e-21
Identities = 101/330 (30%), Positives = 142/330 (43%), Gaps = 39/330 (11%)
Query: 397 KQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPN 456
K+ R K + RD+ S + R+ RSRSP R +SRSP+
Sbjct: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRE--RSRSPR----RRKSRSPS 181
Query: 457 KARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS-----KERQCRQ 511
R RS + R RS SRSP + R S+ SP+ E+ + P KE ++
Sbjct: 182 PRR---RSSPVRRERKRSHSRSP-RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
Query: 512 SRSSS------KERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSK 565
+ S+S K + PS E+ ++ + K R RS+SRS S R +SRSPS
Sbjct: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS--RSRTRSRSPSH 295
Query: 566 ERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSK 625
R RRR RS S+ R+ R S R R R+P PR H RSR+P +
Sbjct: 296 TRPRRRHRSRSRSYSPRR-RPSPRRRPSPRRRTP--------PRRMPPPPRHRRSRSPVR 346
Query: 626 EGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQT 685
S S + S S S S+ RSP K+ P RTSS P KT SPS P +
Sbjct: 347 RRRRS-SASLSGSSSSSSSSRSRSPP-KKPPKRTSS-----PPRKTRRLSPSASPPRRRH 399
Query: 686 LSQDDSQADATTSKATLPGERSSSSSSKLA 715
+ T + P + + + S+++
Sbjct: 400 RPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429
Score = 102 bits (254), Expect = 1e-21
Identities = 116/394 (29%), Positives = 165/394 (41%), Gaps = 67/394 (17%)
Query: 361 KERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY 420
K+R + +S ++ KE + S ++R+ RSRSP R +SRS SP
Sbjct: 132 KQRQIEQEKLASMKKQDEDKDKRDKE----EKESSREKRE--RSRSPR--RRKSRSPSP- 182
Query: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480
R RS + R S SRSP R R++SRSP+ A + + ++P + + PS
Sbjct: 183 ----RRRSSPVRRERKRSHSRSP---RHRTKSRSPSPAPE-KKEKTPELPEPSVKVKEPS 234
Query: 481 KERDHS--------------QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS 526
+ S + PS E++ ++ + K R +SRS SK R RSRS
Sbjct: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRP--RSRSRSKSRSRTRSRS 292
Query: 527 PSKERQRR----QSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR 582
PS R RR +SRS + R S R PS R R P R RR RSP + R R
Sbjct: 293 PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRS-RSPVRRRRRS 351
Query: 583 QS--RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD 640
+ SS SRSRSP K+ P+ +S +R +PS + R S +
Sbjct: 352 SASLSGSSSSSSSSRSRSPPKKP----PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP 407
Query: 641 PSQSTVPRSPDWKRSPTRTS--SLSQNRTPSKTSSH-------SPSTFP----------- 680
P ++ +P + + TR S S+S RT K + H SPS P
Sbjct: 408 PPKTRHSPTPQ-QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESE 466
Query: 681 --SGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
GG+ + D Q + S SSS
Sbjct: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
Score = 94.7 bits (234), Expect = 3e-19
Identities = 129/558 (23%), Positives = 224/558 (40%), Gaps = 93/558 (16%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
S +R + S SL+ S SS ++ + P ++++P R P+ S S
Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS 402
Query: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
+T T+ +P+ + S+R+R + +P R S K +K +GT R
Sbjct: 403 PPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS-----GKVTK--------HKGTEKR- 448
Query: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
SPS A P ++ + ++ S Q+ + + + +S+
Sbjct: 449 ------------ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS 496
Query: 182 ERSDSQPRNLSKKSYRPPGGSGIGR--SSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSS 239
S S K+S+ G G R S + +PS K Q T P + +PSP +
Sbjct: 497 GSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS-PRGRRRRSPSPPPT 555
Query: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTH 299
R+ +S P R ++ +P P+ + S PRR RS S +R
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPP-----------------PRRRTPSPPPRR-RSPSPRRYS 597
Query: 300 SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNP 359
+ +R +S + R+ + S + + S P+R SH+ P
Sbjct: 598 PPI-----QRRYSPSPPPKRR---------TASPPPPPKRRASPSPPPKRRVSHS---PP 640
Query: 360 SKERSH--SHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHS-RSRSPNKARD---- 412
K+RS + RS S HR SSP + + ++S PNK+ S R R+P +
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700
Query: 413 -RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR 471
R S SP + + S S P R SR+ P K + ++ S SP R S SRS + +
Sbjct: 701 RRGASSSPQRRQSPSPSTRP--IRRVSRTPEPKKIK-KAASPSPQSVRRVSSSRSVSGSP 757
Query: 472 DRSRSR-----SPSKERDHSQLGSPSKERDHRRSRSPS-------------KERQCRQSR 513
+ + + SP + + S SP+ +S +PS K+++ ++ +
Sbjct: 758 EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDK 817
Query: 514 SSSKERDHRRSRSPSKER 531
K++ H++ + KE+
Sbjct: 818 KHKKDKKHKKHKKHKKEK 835
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
sapiens]
Length = 2365
Score = 155 bits (393), Expect = 9e-38
Identities = 175/713 (24%), Positives = 305/713 (42%), Gaps = 116/713 (16%)
Query: 39 TPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDT 98
T S+ P S S SP+ + ++ ST+ P R SS R+ R SR S+
Sbjct: 241 TQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIP--RASSPHRITQ--RDTSRASSTQ 296
Query: 99 RTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRV 158
+ + S+AS + R + ++ TP R S + + +P +ST +
Sbjct: 297 Q--EISRASSTQQETSRASSTQEDTP--RASSTQEDTPRASST---------------QW 337
Query: 159 RTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAK 218
TP + SR PRTS+ ++ + Q +S TP
Sbjct: 338 NTPRASSP-SRSTQLDNPRTSSTQQDNPQ-------------------TSFPTCTPQREN 377
Query: 219 CQTPTGIPSKEKSDNPSPSSSRKVK--SYGQMIIPSREKSYSPTEMSSRVKSYNQASTRS 276
+TP ++ +P+ ++ R+ S Q P ++ SP ++R + R
Sbjct: 378 PRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNR-ATRDNPRTSCAQRD 436
Query: 277 RPQSHSQSR--------------SPRRSRSGSQKR-THSRVRSHSWKRNHSRARSRTRKG 321
P++ S SR +PR SR+ S R T R+ +R++ RA S +R
Sbjct: 437 NPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSR-- 494
Query: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSS 381
R + + S ++ + SRT R+ + + R+S +RD+ +S
Sbjct: 495 ----ATRDNPTTSCAQRDNPRASRTSSPNRA-----------TRDNPRTSCAQRDNPRAS 539
Query: 382 SPRKESGRSQSGSPNKQRDH---SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA-RDC 437
SP + + R + QRD+ SR+ SPN+A R R+ RD R+ SPN+A RD
Sbjct: 540 SPNR-AARDNPTTSCAQRDNPRASRTSSPNRA-TRDNPRTSCAQRDNPRASSPNRATRDN 597
Query: 438 SRSRSPYKARDR-SRSRSPNKA-----------RDHSRSRSPNKARDRSRSRSPSKERDH 485
+ + R SR+ SPN+A RD+ R+ SPN+ + R+ RD
Sbjct: 598 PTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDD 657
Query: 486 SQLGSPSKE------------RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQR 533
+ SP++ RD+ R+ SPS+ Q R+S +RD R+ SP++ Q+
Sbjct: 658 PRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQ 717
Query: 534 RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDH 593
R+ RD ++ S + + R+ +RD R SP++ ++ R+S +D+
Sbjct: 718 ENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDN 777
Query: 594 SRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTV----PRS 649
R+ SPN+ + PR S ++ + R+ +P + RT +++ P S+ P++
Sbjct: 778 PRTSSPNRAT-RDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKT 836
Query: 650 PDWKRSPTRTSSLSQNRTPS-KTSSHSPSTFPSGGQTLSQDDSQADATTSKAT 701
KR R + ++RT S +P T S Q +Q ++ ++ ++T
Sbjct: 837 SCTKRDNLRPTCTQRDRTQSFSFQRDNPGT--SSSQCCTQKENLRPSSPHRST 887
Score = 154 bits (390), Expect = 2e-37
Identities = 180/678 (26%), Positives = 290/678 (42%), Gaps = 83/678 (12%)
Query: 86 SKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSR--SSKRSPSRASTPG 143
++ R S +S + S ++AS + H + + +P +R + +S R RAS+P
Sbjct: 223 ARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPH 282
Query: 144 RIR---THGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPG 200
RI T A R ++QQ+ SR S + PR S + P
Sbjct: 283 RITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPR-ASSTQWNTPR 341
Query: 201 GSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPT 260
S RS++L P T+ Q DNP S P RE +P
Sbjct: 342 ASSPSRSTQLD-NPRTSSTQ----------QDNPQTSFPT--------CTPQRENPRTPC 382
Query: 261 EMSS--RVKSYNQASTRSRPQ-SHSQSRSPRRSRSGSQKR-THSRVRSHSWKRNHSRARS 316
R S N+ + R + S +Q +P+ SR+ S R T R+ +R++ RA S
Sbjct: 383 VQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASS 442
Query: 317 RTRKGILSQMGRHSQSRSHSKGKSQNQSRT--PRRGRSHNWSRNPSKERSHSHSRSSSKE 374
+R R + + S ++ + SRT P R N R +R + + S S+
Sbjct: 443 PSRAT------RDNPTTSCAQRDNPRASRTSSPNRATRDN-PRTSCAQRDNPRASSPSRA 495
Query: 375 -RDHRGSSSPRKESGR-SQSGSPNK-----------QRDHSRSRSPNKA-RDRSRSRSPY 420
RD+ +S ++++ R S++ SPN+ QRD+ R+ SPN+A RD +
Sbjct: 496 TRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQ 555
Query: 421 KARDR-SRSRSPNKA-RDCSRSRSPYKARDRSRSRSPNKA-RDH-------------SRS 464
+ R SR+ SPN+A RD R+ RD R+ SPN+A RD+ SR+
Sbjct: 556 RDNPRASRTSSPNRATRD--NPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRT 613
Query: 465 RSPNKA-----------RDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSR 513
SPN+A RD R+ SP++ + RD R+ SP++ Q R
Sbjct: 614 SSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPR 673
Query: 514 SSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWR 573
+S RD+ R+ SPS+ Q+ R+ +RD ++ SP+ + R+ RD R
Sbjct: 674 TSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRAS 733
Query: 574 SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSR 633
S ++ +R R+S +RD+ R+ SPN+ R S + + R+ +P++ R
Sbjct: 734 SRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNR-ATRDNPR 792
Query: 634 TSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693
TS + D +++ P + +P RT S T +P T + L +Q
Sbjct: 793 TSCAQRDNLRASSPIRATQQDNP-RTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQR 851
Query: 694 DATTSKATLPGERSSSSS 711
D T S + +SSS
Sbjct: 852 DRTQSFSFQRDNPGTSSS 869
Score = 151 bits (381), Expect = 2e-36
Identities = 175/740 (23%), Positives = 305/740 (41%), Gaps = 80/740 (10%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASL---KSTKSATPNRSLVPTKPATSRNSVMS 58
S+ + +S+ S + + + T + P AS + ++++P+RS P TS +
Sbjct: 304 STQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDN 363
Query: 59 PSSSKST-----KSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTS-KASKASDVRCH 112
P +S T ++ T + P + S R+ R SR S R + KAS+ S
Sbjct: 364 PQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSS---- 419
Query: 113 QRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKS 172
R T RT ++R RAS+P R A R S+ +
Sbjct: 420 PNRATRDNPRTS------CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRAT 473
Query: 173 YGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSD 232
PRTS +R + + + S+ + P S R + A + T P++ D
Sbjct: 474 RDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRA---------SRTSSPNRATRD 524
Query: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
NP S +++ + R S N+A+ + S +Q +PR SR+
Sbjct: 525 NPRTSCAQRD--------------------NPRASSPNRAARDNPTTSCAQRDNPRASRT 564
Query: 293 GSQKR-THSRVRSHSWKRNHSRARSRTRKG------ILSQMGRHSQSRSHSKGKS-QNQS 344
S R T R+ +R++ RA S R +Q SR+ S ++ ++
Sbjct: 565 SSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP 624
Query: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS 404
RT R + + +P++ R+S RD +SSP + + + RD+ R+
Sbjct: 625 RTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRA 684
Query: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
SP++ + R+ RD R+ SPN+ R+ RD R+ S N+
Sbjct: 685 SSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNP 744
Query: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS 524
R+ RD R+ SP++ L + +D+ R+ SP++ + R+S +RD+ R+
Sbjct: 745 RTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATR-DNPRTSCAQRDNLRA 803
Query: 525 RSPSKERQRRQSRS---PNKERDRS-QSRSPSEEREHRQSRSPS-KERDRRRWRSPSKER 579
SP + Q+ R+ N R S Q +P R + P+ +RDR + S ++
Sbjct: 804 SSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDN 863
Query: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK-------AHSRSRTPSKEGNHSQS 632
S ++++ R SP++ + ++ PR SS + A R +G + S
Sbjct: 864 PGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSS 923
Query: 633 RTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692
+ SK+S+ +++ P P Q +PS+ + H P S G T S+
Sbjct: 924 PSRSKQSEVPWASIALRPTQGDRP-------QTSSPSRPAQHDPPQ-SSFGPTQYNLPSR 975
Query: 693 ADATTSKATLPGERSSSSSS 712
A TS + PG +S+S +S
Sbjct: 976 A---TSSSHNPGHQSTSRTS 992
Score = 37.4 bits (85), Expect = 0.049
Identities = 72/306 (23%), Positives = 104/306 (33%), Gaps = 38/306 (12%)
Query: 380 SSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS- 438
S SP G S P + R + D R R R P CS
Sbjct: 1243 SPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPR-------RLAQRQPGPQAQCSS 1295
Query: 439 --RSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERD 496
R+ SP +A R + R S + +A+D RS+ PS+ + S
Sbjct: 1296 GGRTHSPGRAEVE---RLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPS 1352
Query: 497 HRRSRSPSKERQCRQSRSSSKERDHRRS--RSPSKERQRRQSRSPNKERDRSQSRSPSEE 554
+ + P+K Q +R S E H S + P +RQ + S P R+ +R+P E
Sbjct: 1353 RQVTMLPAK--QAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLP----PRTSARTP--E 1404
Query: 555 REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE 614
RE R R E + R P + ++ S+ RS + Q G P
Sbjct: 1405 RELRTQR--PLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGC 1462
Query: 615 KAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674
S + EG + KES W+ PT + P +
Sbjct: 1463 GEPSLGAAKAPEGAWGGTSREYKESWGQPEA------WEEKPT-------HELPRELGKR 1509
Query: 675 SPSTFP 680
SP T P
Sbjct: 1510 SPLTSP 1515
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 155 bits (391), Expect = 2e-37
Identities = 186/732 (25%), Positives = 290/732 (39%), Gaps = 100/732 (13%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPT---------KPATS 52
SSPK SS S S P D + + +K P P K
Sbjct: 223 SSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKE 282
Query: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKA---RTPSRVSTDTRTSKASKASDV 109
+ V K+ R + R + RS + + S +S+ +S + S +
Sbjct: 283 KYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSI 342
Query: 110 RCH----QRRGTHS----RGRTPGRRGSRS-----SKRSPSRASTPGRIRTHGARPGMAS 156
+ H +R+ T S R TP R S S S SP R +P R R+ G
Sbjct: 343 QRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHD 402
Query: 157 RVRTPTS------QQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSEL 210
RT S +++ +RGK R + S ER Q ++ S + +R GR
Sbjct: 403 HERTSQSHDRRHERREDTRGKR-DREKDSREEREYEQDQS-SSRDHRDDREPRDGRDRRD 460
Query: 211 AVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYN 270
A + E D+ SR+++ Y + SR+ P + S +++
Sbjct: 461 ARDTRDRR----------ELRDSRDMRDSREMRDYSRDTKESRD----PRDSRSTRDAHD 506
Query: 271 QASTRSRPQSHSQSRSPRRSRSGSQK-----------RTHSRVRSHSWKRNHSRARSRTR 319
R + P SRS + R SR S S RN RSR R
Sbjct: 507 YRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGR 566
Query: 320 KGILSQMG----RHSQSRSHSKGKS-----QNQSRTPRRGR-----SHNWSRNPSKERSH 365
L + G R SQ SHS + + +S P R R + + +R+ S ER H
Sbjct: 567 VPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRH 626
Query: 366 SH-SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSR-----SRSPNKARDRSRSRSP 419
R ++ERD R SSP + GR+ +++R+ R R +AR+R R R
Sbjct: 627 GERDRRDNRERDQR-PSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERER 685
Query: 420 YKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSP 479
+ R+R R R ++ R+ R +AR+R R R + R+ R R ++ R+R R R
Sbjct: 686 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDR 745
Query: 480 SKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP 539
KER+ + +ER+ R R +ER+ +ER+ R+R KER+R++
Sbjct: 746 EKERERER-----EERERERERERERERE--------RERERERARERDKERERQRDWE- 791
Query: 540 NKERDRSQSRSPSEE-REHRQSRSPSKER-DRRRWR---SPSKERERRQSRSSSEERDHS 594
+K++ R R EE RE R R ER ++R+R SPS + ++ R S + D
Sbjct: 792 DKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAY 851
Query: 595 RSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKR 654
S + R + SRS +PS Q R ++ P + R + +
Sbjct: 852 NSGDDKNEK--HRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 909
Query: 655 SPTRTSSLSQNR 666
+ SS+ + R
Sbjct: 910 LKEKVSSVDKQR 921
Score = 147 bits (370), Expect = 4e-35
Identities = 183/713 (25%), Positives = 274/713 (38%), Gaps = 83/713 (11%)
Query: 57 MSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRG 116
+SP +S S S PS R SS+S R + P S + K S S Q+R
Sbjct: 197 VSPEVVRSKLSPS----PSLRKSSKSPKRKSS--PKSSSASKKDRKTSAVSSPLLDQQR- 249
Query: 117 THSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRP 176
+S+ ++G R+ P + + + + R+ T K RG+ + R
Sbjct: 250 -NSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGK-DRGRDFERQ 307
Query: 177 RTSNRERSDSQP--RNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTP------TGIPSK 228
R + + P ++ S S R S SS +PS + +TP T P
Sbjct: 308 REKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPL 367
Query: 229 EKSDNPSPSSS----RKVKSYGQMIIPSREKS---YSPTEMSSRVKSYNQASTRSRPQSH 281
+S +P PS S ++ +S + P REK + T S + + TR +
Sbjct: 368 RRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDRE 427
Query: 282 SQSRSPRR-SRSGSQKRTHSRVRSHSWKRNHSRAR-SRTRKGILSQMGRHSQSRSHSKGK 339
SR R + S R H R R+ AR +R R+ + +
Sbjct: 428 KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 487
Query: 340 SQNQSRTPRRGRS----HNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSP 395
+SR PR RS H++ ++ +H + +E G + R+ES R++
Sbjct: 488 DTKESRDPRDSRSTRDAHDYRDREGRD-THRKEDTYPEESRSYGRNHLREESSRTEIR-- 544
Query: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSR---------SPNKARDCSRSRSPYKA 446
N+ R+ SRS N RSR R P SR S + D +RS Y
Sbjct: 545 NESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPE 604
Query: 447 RDRSRSR-SPNKARDHS-------RSRSPNKARD-------RSRSRSPSKERDHSQ---- 487
RDR R + ++ARD S R R N+ RD R + R+ ERD +
Sbjct: 605 RDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664
Query: 488 LGSPSKERDHR-RSRSPSKERQCRQSRSSSKERDHRR--SRSPSKERQRRQSRSPNKERD 544
+ RD R R R +ER + R +ERD R R +ER R + R KERD
Sbjct: 665 VDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERD 724
Query: 545 RSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604
R + R +RE + R +E++R R R +ERER + R ER+ R R
Sbjct: 725 RERDRDRDHDRERERERERDREKERERER---EERERERERERERERERERERE------ 775
Query: 605 YSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTR---TSS 661
RA ++K R R + R +E D ++S R S
Sbjct: 776 ----RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGS 831
Query: 662 LSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKL 714
S ++P + HSP S D ++ S+ P E S S S L
Sbjct: 832 PSPRQSPKRRREHSPD---SDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHL 881
Score = 123 bits (308), Expect = 7e-28
Identities = 179/825 (21%), Positives = 296/825 (35%), Gaps = 142/825 (17%)
Query: 7 SSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTK 66
SS+ S + SGSS+ P P K T S + R+L P ++ SP S S
Sbjct: 328 SSRHHSSSSQSGSSIQRHSPSPRR--KRTPSPSYQRTLTPPLRRSA-----SPYPSHSLS 380
Query: 67 STSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGR 126
S K++P P RS +R K R ++ + + + D R + R SR
Sbjct: 381 SPQRKQSP---PRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYE 437
Query: 127 RGSRSSK-RSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSD 185
+ SS+ R GR R +R + + Y R +R+ D
Sbjct: 438 QDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRD 497
Query: 186 SQPRNLSKKSYRPPGGSGIGRSSELAVTPSTA-------KCQTPTGIPSKEKSDNPSP-S 237
S+ YR G R + S + + + T I ++ ++++ S
Sbjct: 498 SRSTR-DAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIR 556
Query: 238 SSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQAST-----RSRPQSHSQSRSPRRSRS 292
+ R +S G+ +P + S S++ S++ S +R + R P R
Sbjct: 557 NDRMGRSRGR--VPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNR 614
Query: 293 GSQKRTHSRVRSHSWK-RNHSRARSRTRKGILSQMGRHSQ--------SRSHSKGKSQNQ 343
Q R S R H + R +R R + + GR+ + R + +
Sbjct: 615 -DQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRD 673
Query: 344 SRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSP--NKQRDH 401
R R R R +ER R KER+ + +E R + ++ RDH
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 402 SRSRSPNKARDRSRSRSPYKA-RDRSRSRSPNKARDCSRSRSPYKARDRSRSRS-----P 455
R R + RDR + R + R+R R R + R+ R R + RD+ R R
Sbjct: 734 DRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDK 793
Query: 456 NKARDHSRS--------RSPNKARDRSRSR-------------SPSKERDHSQ-----LG 489
+K RD R R+P D +S+ SP + R+HS
Sbjct: 794 DKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNS 853
Query: 490 SPSKERDHR-----------RSRSPSKERQCRQSRSSSKERDHRRSRSP----------- 527
K HR RS SPS + RQ R ++R R S
Sbjct: 854 GDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEK 913
Query: 528 --SKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWR------------ 573
S ++QR Q+ R R+Q + E R++ + + ++++ +
Sbjct: 914 VSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKED 973
Query: 574 -------------------SPSK-------ERERRQSRSSSEERDHSRSRSPNKQSGYSR 607
SP K E++R++S+ S+ D ++ K+ G
Sbjct: 974 DVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRT 1033
Query: 608 PRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRT 667
P ++KE+ + SQ + + SD S VP + + ++ + T
Sbjct: 1034 PPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGST 1093
Query: 668 PSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
PS SS P P + A ATT ATL +++++S
Sbjct: 1094 PSPLSSLLPPPPPV---------ATATATTVPATLAATTAAAATS 1129
Score = 76.3 bits (186), Expect = 9e-14
Identities = 159/685 (23%), Positives = 238/685 (34%), Gaps = 74/685 (10%)
Query: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDV-RC 111
RN KS K + +PS R S + R + + S D + K S V R
Sbjct: 811 RNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRP 870
Query: 112 HQRRGTHSRGRTPGRRGS-RSSKRSPSRASTPGRIRTHGARPGMAS--RVRTPTSQQKGS 168
+ R T R+G + R P R + R + ++S + R T + S
Sbjct: 871 QESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESS 930
Query: 169 RGKSY---GRPRTSNRERSDS-----------QPRNLSKKSYRPPG--GSGIGRSSELAV 212
R ++ G ++ +RE SD Q + + KK G I +SE
Sbjct: 931 RMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQ 990
Query: 213 TPSTAKCQTPTGIPSKEK--------SDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSS 264
S K Q I K K SD + S+K + I ++E+ +
Sbjct: 991 VFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKN 1050
Query: 265 RVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSR----------A 314
+ +Q + S P R+ + T + S S A
Sbjct: 1051 GILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATA 1110
Query: 315 RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE 374
+ T L+ + + + + + S TP ++ ++ S + H +R E
Sbjct: 1111 TATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCH-RTRVEKVE 1169
Query: 375 RDH-----RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS-RSRSPYKARDRSRS 428
H P + S GS R H+ R + + D + RS R R
Sbjct: 1170 TPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLH 1229
Query: 429 RSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQL 488
+RD +++S +R K + SRS S DR SRS S R
Sbjct: 1230 SG---SRDREKTKSLEITGERKSRIDQLKRGEPSRSTSS----DRQDSRSHSSRRS---- 1278
Query: 489 GSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQS 548
SP +R SRS S + + R E D R R RQR R +K+ R++
Sbjct: 1279 -SPESDRQVH-SRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRD 1336
Query: 549 RSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRP 608
R ERE +ER+R + R +ERER S S +RD R R+ S
Sbjct: 1337 RDRLRERE--------RERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVK 1388
Query: 609 RASSK-EKAHSRSRTPSKEGNHSQSRTSSKE-SDPSQSTVPRSPDWKRSPTRTSSLSQNR 666
R +K E H R E S KE D +V + +S RT SL
Sbjct: 1389 RCEAKLEGEHER----DLESTSRDSLALDKERMDKDLGSVQGFEETNKS-ERTESLEAGD 1443
Query: 667 TPSK-TSSHSPSTFPSGGQTLSQDD 690
SK +HS + G DD
Sbjct: 1444 DESKLDDAHSLGSGAGEGYEPISDD 1468
Score = 62.8 bits (151), Expect = 1e-09
Identities = 82/338 (24%), Positives = 135/338 (39%), Gaps = 30/338 (8%)
Query: 346 TPR-RGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS 404
+PR +G S N+ R+P + R +K +D + P+K + S K+ R
Sbjct: 64 SPRGKGYSSNYRRSPERPTGDLRERMKNKRQDV--DTEPQKRNTEESSSPVRKESSRGRH 121
Query: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
R + ++ R+P + + D Y + R+ +
Sbjct: 122 REKEDIK-ITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKL 180
Query: 465 RSPN--KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR 522
N K + + S E S+L SPS + S+SP ++ + S +S K+R
Sbjct: 181 EQENMEKREEIIIKKEVSPEVVRSKL-SPSPSL-RKSSKSPKRKSSPKSSSASKKDRKTS 238
Query: 523 RSRSPSKERQRRQSRSPNKER-DRSQSRSPS-----------EEREHRQSRSPSKERD-R 569
SP ++QR + +K++ R+ S P +E+ + R K RD +
Sbjct: 239 AVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGK 298
Query: 570 RRWRSPSKERERR-QSRSSSEERDH-----SRSRSPNKQSGYSRPRASSKEKAHSRSRTP 623
R R ++RE+R + RS+S H SR S + QSG S R S + R RTP
Sbjct: 299 DRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPR---RKRTP 355
Query: 624 SKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSS 661
S + + + + P S SP K+SP R S
Sbjct: 356 SPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRS 393
Score = 47.0 bits (110), Expect = 6e-05
Identities = 79/379 (20%), Positives = 129/379 (34%), Gaps = 63/379 (16%)
Query: 7 SSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTK 66
++ P + +P S +P P PP + + + + ATS ++ S+ +T
Sbjct: 1087 ATTPGSTPSPLSSLLP---PPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATP 1143
Query: 67 STSTKRAPSNRPSSRSRVRS---KARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRT 123
+ +T +N S R R+ K TP D + H +
Sbjct: 1144 TNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQ------------------HRKPMD 1185
Query: 124 PGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRER 183
R S S RS +R+ T GR+R+ P S R+ Q GR R +
Sbjct: 1186 QKRSSSLGSNRS-NRSHTSGRLRS----PSNDSAHRSGDDQS--------GRKRVLH--- 1229
Query: 184 SDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVK 243
S S+ R +K S E+ + Q G PS+ S + S S +
Sbjct: 1230 SGSRDREKTK-------------SLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSR 1276
Query: 244 SYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVR 303
R S ++ SR S++ + R R R +++R R
Sbjct: 1277 ---------RSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDA 1327
Query: 304 SHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER 363
W RN R R R R+ + R R + S + R R R + + +
Sbjct: 1328 DKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESV 1387
Query: 364 SHSHSR-SSSKERDHRGSS 381
++ ERD +S
Sbjct: 1388 KRCEAKLEGEHERDLESTS 1406
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 151 bits (381), Expect = 2e-36
Identities = 111/364 (30%), Positives = 176/364 (48%), Gaps = 44/364 (12%)
Query: 315 RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE 374
+S RKG +SRSH++ KS++ S++ R + R+ SK RS SH+RS S++
Sbjct: 299 KSNERKG--------GRSRSHTRSKSRSSSKSHSRRK-----RSQSKHRSRSHNRSRSRQ 345
Query: 375 RDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA 434
+D R S SP K+ +S+ ++ R HSR + + R++ + + K +DR + R K
Sbjct: 346 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD-TREKIKEKERVKEKDREKEREREKE 404
Query: 435 RDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKE 494
R+ + R K RD+ R + K ++ R R K ++ R + KE+D KE
Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKE------KE 458
Query: 495 RDHRRSRSPSKERQCRQSRSSSKERDH---RRSRSPSKERQRRQSRSPNKERDRSQSRSP 551
R+ RS+ ++R+ + +S + R + RRSRS S+ER+RR R RS SRSP
Sbjct: 459 REKDRSKEIDEKRK-KDKKSRTPPRSYNASRRSRSSSRERRRR--------RSRSSSRSP 509
Query: 552 --SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609
S+ + + SRSPS ++ + KER+ SE R+ RS S K S
Sbjct: 510 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDH-----ISERRERERSTSMRKSSN----D 560
Query: 610 ASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPS 669
KEK S T KE H++ SS + PR+ + K L++ +
Sbjct: 561 RDGKEKLEKNS-TSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLST 619
Query: 670 KTSS 673
KT +
Sbjct: 620 KTEA 623
Score = 134 bits (338), Expect = 2e-31
Identities = 107/357 (29%), Positives = 164/357 (45%), Gaps = 25/357 (7%)
Query: 354 NWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDR 413
N S N + ++++KE + +S S + P + + R +++ R
Sbjct: 254 NHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTR 313
Query: 414 SRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDR 473
S+SRS K+ R R RS +K R S +RS + +DR RS+SP+K R S+SR K+R R
Sbjct: 314 SKSRSSSKSHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR--SKSRERRKSRSR 370
Query: 474 SRSRSPSKE-RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRR--SRSPSKE 530
S SR K+ R+ + KE+D + R KER+ + R +K+RD R R KE
Sbjct: 371 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 430
Query: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRS------PSKERERRQS 584
+ R + R E+DR + + +++E + + SKE D +R + P R+S
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 490
Query: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD--PS 642
RSSS ER RSRS ++ PR S K S SR+PS + + + KE D
Sbjct: 491 RSSSRERRRRRSRSSSRS-----PRTSKTIKRKS-SRSPSPRSRNKKDKKREKERDHISE 544
Query: 643 QSTVPRSPDWKRSPT---RTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADAT 696
+ RS ++S L +N T K H+ P + DD A T
Sbjct: 545 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE--PDSSVSKEVDDKDAPRT 599
Score = 132 bits (332), Expect = 1e-30
Identities = 97/336 (28%), Positives = 174/336 (51%), Gaps = 38/336 (11%)
Query: 380 SSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSR 439
S++ ESG+S + R H+RS+S + ++ SR R RS+S +++R +R
Sbjct: 290 SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR---------RKRSQSKHRSRSHNR 340
Query: 440 SRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRR 499
SRS + +DR RS+SP+K R SR R + RSRS S K +D ++E+ +
Sbjct: 341 SRS--RQKDRRRSKSPHKKRSKSRERR----KSRSRSHSRDKRKD-------TREKIKEK 387
Query: 500 SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQ 559
R K+R+ + R +E++ R ++ ++++R + R +KE+DR + R E+EH +
Sbjct: 388 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER----EKEHEK 443
Query: 560 SRSPSKERDRRRWRSPSKERERRQSRSSSEER-DHSRSRSPNKQSGYS-RPRASSKEKAH 617
R KE+++ + KERE+ +S+ E+R +SR+P + S R R+SS+E+
Sbjct: 444 DRDKEKEKEQDK----EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 499
Query: 618 SRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPS 677
RSR+ S+ + S+T ++S S S R+ K+ +S+ R +++S S
Sbjct: 500 RRSRSSSR--SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557
Query: 678 TFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
+ G ++ + ++T+ K + SS SK
Sbjct: 558 SNDRDG----KEKLEKNSTSLKEKEHNKEPDSSVSK 589
Score = 127 bits (320), Expect = 3e-29
Identities = 93/316 (29%), Positives = 150/316 (47%), Gaps = 30/316 (9%)
Query: 291 RSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRG 350
R G + R+H+R +S S ++HSR RK S+ S +RS S+ K + +S++P +
Sbjct: 303 RKGGRSRSHTRSKSRSSSKSHSR-----RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 357
Query: 351 RSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR-KESGRSQSGSPNKQRDHSRSRSPNK 409
RS SR K RS SHSR K+ + R KE R + K+R+ + R NK
Sbjct: 358 RSK--SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415
Query: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARD-------HS 462
RD+ R + K +++ R R K + R + K +D+ + R +++++
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475
Query: 463 RSRSPNKA-----RDRSRSRSPSKERDHSQLGSP--SKERDHRRSRSPSKERQCRQSRSS 515
+SR+P ++ R RS SR + R S SP SK + SRSPS + ++ +
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 535
Query: 516 SKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSP 575
KERDH S+ R+R +S S K S R E+ E + KE ++ S
Sbjct: 536 EKERDH-----ISERRERERSTSMRKS---SNDRDGKEKLEKNSTSLKEKEHNKEPDSSV 587
Query: 576 SKERERRQSRSSSEER 591
SKE + + + + E +
Sbjct: 588 SKEVDDKDAPRTEENK 603
Score = 116 bits (290), Expect = 8e-26
Identities = 92/325 (28%), Positives = 155/325 (47%), Gaps = 26/325 (8%)
Query: 254 EKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSR 313
E S R +S+ ++ +RS +SHS RR RS S+ R+ S RS S +++ R
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHS-----RRKRSQSKHRSRSHNRSRSRQKDRRR 350
Query: 314 ARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSK 373
++S +K S+ R S+SRSHS+ K ++ +R + + ++ KER R K
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKD-TREKIKEKERVKEKDREKEREREKEREKEK 409
Query: 374 ERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRS-PN 432
ER +E R + +++R+ + ++ +++ + + K R++ RS+
Sbjct: 410 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469
Query: 433 KARDCSRSRSPYKA-----RDRSRSRSPNKARDHSRSRSP--NKARDRSRSRSPSKERDH 485
K + +SR+P ++ R RS SR + R S SRSP +K R SRSPS +
Sbjct: 470 KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN 529
Query: 486 SQLGSPSKERDHRRSRSPSKERQCRQS-RSSSKERDHRRSRSPSKERQRRQSRSPNKERD 544
+ KERDH R +ER+ S R SS +RD KE+ + S S KE++
Sbjct: 530 KKDKKREKERDHISER---RERERSTSMRKSSNDRD-------GKEKLEKNSTS-LKEKE 578
Query: 545 RSQSRSPSEEREHRQSRSPSKERDR 569
++ S +E +P E ++
Sbjct: 579 HNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 72.8 bits (177), Expect = 1e-12
Identities = 82/369 (22%), Positives = 143/369 (38%), Gaps = 62/369 (16%)
Query: 121 GRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN 180
G++ R+G RS RS +R+ + ++H R S+ R+ + + SR K R ++ +
Sbjct: 298 GKSNERKGGRS--RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 355
Query: 181 RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
++RS S+ R S+ S+ S + +
Sbjct: 356 KKRSKSRERRKSR---------------------------------SRSHSRDKRKDTRE 382
Query: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHS 300
K+K ++ REK R K + R + + + R R + + R
Sbjct: 383 KIKEKERVKEKDREKE------REREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436
Query: 301 RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS 360
R + H R+ + + + ++ + + K K +SRTP R S+N SR
Sbjct: 437 REKEHEKDRDKEKEKEQDKE---KEREKDRSKEIDEKRKKDKKSRTPPR--SYNASR--- 488
Query: 361 KERSHSHSRSSSKERDHRGSSSPR--KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
RS S SR + R S SPR K R S SP+ + + + + K RD R
Sbjct: 489 --RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER- 545
Query: 419 PYKARDRSRSRSPNKARDCSRSRSPYKARDRS-RSRSPNKARDHSRSRSPNKARDRSRSR 477
R+R RS S K+ + + + S + + NK D S S+ + D+ R
Sbjct: 546 ----RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK---EVDDKDAPR 598
Query: 478 SPSKERDHS 486
+ + H+
Sbjct: 599 TEENKIQHN 607
Score = 72.0 bits (175), Expect = 2e-12
Identities = 86/354 (24%), Positives = 139/354 (39%), Gaps = 20/354 (5%)
Query: 44 LVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRS--RVRSKARTPSRVSTDTRTS 101
+ P A VM + ++ S + + R R RS R+ SR S+ + +
Sbjct: 266 MTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR 325
Query: 102 KASKASDVRCHQRRGTHSRGRTPGRRGSRS--SKRSPSRASTPGRIRTHGARPGMASRVR 159
+ K S + R SR R RR S+S KRS SR R R+H +R +
Sbjct: 326 R--KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 383
Query: 160 TPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKC 219
++ + + R R RE+ + +N + R R + +
Sbjct: 384 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK-----DREKDKEKDRERERE 438
Query: 220 QTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQ 279
+ KEK R+ K + I R+K + + +SYN AS RSR
Sbjct: 439 KEHEKDRDKEKEKEQDKEKERE-KDRSKEIDEKRKKD---KKSRTPPRSYN-ASRRSR-- 491
Query: 280 SHSQSRSPRRSRSGSQK-RTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKG 338
S S+ R RRSRS S+ RT ++ S + R+R++ K + S+ R +
Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
Query: 339 KSQNQSRTPRRGRSHNWSRNPS-KERSHSHSRSSSKERDHRGSSSPRKESGRSQ 391
S +S R G+ + S KE+ H+ SS ++ +PR E + Q
Sbjct: 552 TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQ 605
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 151 bits (381), Expect = 2e-36
Identities = 111/364 (30%), Positives = 176/364 (48%), Gaps = 44/364 (12%)
Query: 315 RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE 374
+S RKG +SRSH++ KS++ S++ R + R+ SK RS SH+RS S++
Sbjct: 183 KSNERKG--------GRSRSHTRSKSRSSSKSHSRRK-----RSQSKHRSRSHNRSRSRQ 229
Query: 375 RDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA 434
+D R S SP K+ +S+ ++ R HSR + + R++ + + K +DR + R K
Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKD-TREKIKEKERVKEKDREKEREREKE 288
Query: 435 RDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKE 494
R+ + R K RD+ R + K ++ R R K ++ R + KE+D KE
Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKE------KE 342
Query: 495 RDHRRSRSPSKERQCRQSRSSSKERDH---RRSRSPSKERQRRQSRSPNKERDRSQSRSP 551
R+ RS+ ++R+ + +S + R + RRSRS S+ER+RR R RS SRSP
Sbjct: 343 REKDRSKEIDEKRK-KDKKSRTPPRSYNASRRSRSSSRERRRR--------RSRSSSRSP 393
Query: 552 --SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609
S+ + + SRSPS ++ + KER+ SE R+ RS S K S
Sbjct: 394 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDH-----ISERRERERSTSMRKSSN----D 444
Query: 610 ASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPS 669
KEK S T KE H++ SS + PR+ + K L++ +
Sbjct: 445 RDGKEKLEKNS-TSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLST 503
Query: 670 KTSS 673
KT +
Sbjct: 504 KTEA 507
Score = 134 bits (338), Expect = 2e-31
Identities = 107/357 (29%), Positives = 164/357 (45%), Gaps = 25/357 (7%)
Query: 354 NWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDR 413
N S N + ++++KE + +S S + P + + R +++ R
Sbjct: 138 NHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTR 197
Query: 414 SRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDR 473
S+SRS K+ R R RS +K R S +RS + +DR RS+SP+K R S+SR K+R R
Sbjct: 198 SKSRSSSKSHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR--SKSRERRKSRSR 254
Query: 474 SRSRSPSKE-RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRR--SRSPSKE 530
S SR K+ R+ + KE+D + R KER+ + R +K+RD R R KE
Sbjct: 255 SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKE 314
Query: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRS------PSKERERRQS 584
+ R + R E+DR + + +++E + + SKE D +R + P R+S
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 374
Query: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD--PS 642
RSSS ER RSRS ++ PR S K S SR+PS + + + KE D
Sbjct: 375 RSSSRERRRRRSRSSSRS-----PRTSKTIKRKS-SRSPSPRSRNKKDKKREKERDHISE 428
Query: 643 QSTVPRSPDWKRSPT---RTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADAT 696
+ RS ++S L +N T K H+ P + DD A T
Sbjct: 429 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE--PDSSVSKEVDDKDAPRT 483
Score = 132 bits (332), Expect = 1e-30
Identities = 97/336 (28%), Positives = 174/336 (51%), Gaps = 38/336 (11%)
Query: 380 SSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSR 439
S++ ESG+S + R H+RS+S + ++ SR R RS+S +++R +R
Sbjct: 174 SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR---------RKRSQSKHRSRSHNR 224
Query: 440 SRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRR 499
SRS + +DR RS+SP+K R SR R + RSRS S K +D ++E+ +
Sbjct: 225 SRS--RQKDRRRSKSPHKKRSKSRERR----KSRSRSHSRDKRKD-------TREKIKEK 271
Query: 500 SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQ 559
R K+R+ + R +E++ R ++ ++++R + R +KE+DR + R E+EH +
Sbjct: 272 ERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER----EKEHEK 327
Query: 560 SRSPSKERDRRRWRSPSKERERRQSRSSSEER-DHSRSRSPNKQSGYS-RPRASSKEKAH 617
R KE+++ + KERE+ +S+ E+R +SR+P + S R R+SS+E+
Sbjct: 328 DRDKEKEKEQDK----EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 383
Query: 618 SRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPS 677
RSR+ S+ + S+T ++S S S R+ K+ +S+ R +++S S
Sbjct: 384 RRSRSSSR--SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441
Query: 678 TFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
+ G ++ + ++T+ K + SS SK
Sbjct: 442 SNDRDG----KEKLEKNSTSLKEKEHNKEPDSSVSK 473
Score = 127 bits (320), Expect = 3e-29
Identities = 93/316 (29%), Positives = 150/316 (47%), Gaps = 30/316 (9%)
Query: 291 RSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRG 350
R G + R+H+R +S S ++HSR RK S+ S +RS S+ K + +S++P +
Sbjct: 187 RKGGRSRSHTRSKSRSSSKSHSR-----RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 241
Query: 351 RSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR-KESGRSQSGSPNKQRDHSRSRSPNK 409
RS SR K RS SHSR K+ + R KE R + K+R+ + R NK
Sbjct: 242 RSK--SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299
Query: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARD-------HS 462
RD+ R + K +++ R R K + R + K +D+ + R +++++
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359
Query: 463 RSRSPNKA-----RDRSRSRSPSKERDHSQLGSP--SKERDHRRSRSPSKERQCRQSRSS 515
+SR+P ++ R RS SR + R S SP SK + SRSPS + ++ +
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 419
Query: 516 SKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSP 575
KERDH S+ R+R +S S K S R E+ E + KE ++ S
Sbjct: 420 EKERDH-----ISERRERERSTSMRKS---SNDRDGKEKLEKNSTSLKEKEHNKEPDSSV 471
Query: 576 SKERERRQSRSSSEER 591
SKE + + + + E +
Sbjct: 472 SKEVDDKDAPRTEENK 487
Score = 116 bits (290), Expect = 8e-26
Identities = 92/325 (28%), Positives = 155/325 (47%), Gaps = 26/325 (8%)
Query: 254 EKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSR 313
E S R +S+ ++ +RS +SHS RR RS S+ R+ S RS S +++ R
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHS-----RRKRSQSKHRSRSHNRSRSRQKDRRR 234
Query: 314 ARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSK 373
++S +K S+ R S+SRSHS+ K ++ +R + + ++ KER R K
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKD-TREKIKEKERVKEKDREKEREREKEREKEK 293
Query: 374 ERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRS-PN 432
ER +E R + +++R+ + ++ +++ + + K R++ RS+
Sbjct: 294 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353
Query: 433 KARDCSRSRSPYKA-----RDRSRSRSPNKARDHSRSRSP--NKARDRSRSRSPSKERDH 485
K + +SR+P ++ R RS SR + R S SRSP +K R SRSPS +
Sbjct: 354 KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRN 413
Query: 486 SQLGSPSKERDHRRSRSPSKERQCRQS-RSSSKERDHRRSRSPSKERQRRQSRSPNKERD 544
+ KERDH R +ER+ S R SS +RD KE+ + S S KE++
Sbjct: 414 KKDKKREKERDHISER---RERERSTSMRKSSNDRD-------GKEKLEKNSTS-LKEKE 462
Query: 545 RSQSRSPSEEREHRQSRSPSKERDR 569
++ S +E +P E ++
Sbjct: 463 HNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 72.8 bits (177), Expect = 1e-12
Identities = 82/369 (22%), Positives = 143/369 (38%), Gaps = 62/369 (16%)
Query: 121 GRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN 180
G++ R+G RS RS +R+ + ++H R S+ R+ + + SR K R ++ +
Sbjct: 182 GKSNERKGGRS--RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 239
Query: 181 RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
++RS S+ R S+ S+ S + +
Sbjct: 240 KKRSKSRERRKSR---------------------------------SRSHSRDKRKDTRE 266
Query: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHS 300
K+K ++ REK R K + R + + + R R + + R
Sbjct: 267 KIKEKERVKEKDREKE------REREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320
Query: 301 RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS 360
R + H R+ + + + ++ + + K K +SRTP R S+N SR
Sbjct: 321 REKEHEKDRDKEKEKEQDKE---KEREKDRSKEIDEKRKKDKKSRTPPR--SYNASR--- 372
Query: 361 KERSHSHSRSSSKERDHRGSSSPR--KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
RS S SR + R S SPR K R S SP+ + + + + K RD R
Sbjct: 373 --RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER- 429
Query: 419 PYKARDRSRSRSPNKARDCSRSRSPYKARDRS-RSRSPNKARDHSRSRSPNKARDRSRSR 477
R+R RS S K+ + + + S + + NK D S S+ + D+ R
Sbjct: 430 ----RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK---EVDDKDAPR 482
Query: 478 SPSKERDHS 486
+ + H+
Sbjct: 483 TEENKIQHN 491
Score = 72.0 bits (175), Expect = 2e-12
Identities = 86/354 (24%), Positives = 139/354 (39%), Gaps = 20/354 (5%)
Query: 44 LVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRS--RVRSKARTPSRVSTDTRTS 101
+ P A VM + ++ S + + R R RS R+ SR S+ + +
Sbjct: 150 MTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR 209
Query: 102 KASKASDVRCHQRRGTHSRGRTPGRRGSRS--SKRSPSRASTPGRIRTHGARPGMASRVR 159
+ K S + R SR R RR S+S KRS SR R R+H +R +
Sbjct: 210 R--KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 267
Query: 160 TPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKC 219
++ + + R R RE+ + +N + R R + +
Sbjct: 268 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK-----DREKDKEKDRERERE 322
Query: 220 QTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQ 279
+ KEK R+ K + I R+K + + +SYN AS RSR
Sbjct: 323 KEHEKDRDKEKEKEQDKEKERE-KDRSKEIDEKRKKD---KKSRTPPRSYN-ASRRSR-- 375
Query: 280 SHSQSRSPRRSRSGSQK-RTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKG 338
S S+ R RRSRS S+ RT ++ S + R+R++ K + S+ R +
Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
Query: 339 KSQNQSRTPRRGRSHNWSRNPS-KERSHSHSRSSSKERDHRGSSSPRKESGRSQ 391
S +S R G+ + S KE+ H+ SS ++ +PR E + Q
Sbjct: 436 TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQ 489
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 143 bits (360), Expect = 6e-34
Identities = 109/439 (24%), Positives = 174/439 (39%), Gaps = 45/439 (10%)
Query: 253 REKSYSPTEMS-SRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNH 311
REK + E R + + R R + + R + R R R R R
Sbjct: 66 REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK 125
Query: 312 SRARSRTRKGILSQMGRHSQS-----RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHS 366
R R R+G + GR Q+ R + + + R R R RN KER
Sbjct: 126 ERERETEREG---ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
Query: 367 HSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRS 426
+R +ER+ + + E S+ G R+ R R +R R + R R
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERG-----RERERERETETETERKRQTDRERDRQRK 237
Query: 427 RSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHS-RSRSPNKARDRSRSRSPSKERDH 485
R K + R+ RD+ R R ++ RD R + + DR R R ++R+
Sbjct: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
Query: 486 SQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDR 545
+ +ER+ R R+ +ER+ + R ++R+ R R +ER+R++ ++ER+R
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
Query: 546 SQSRSPSEEREH---------RQSRSPSKERDRRRWRSPSKERERR--QSRSSSEERDHS 594
R + E RQS +ER+R R R KERER+ + R E +
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 595 RSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSK----------------- 637
R R +++S R R +EK R R ++ + R +
Sbjct: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVV 477
Query: 638 ESDPSQSTVPRSPDWKRSP 656
+SDP++ T R WK SP
Sbjct: 478 QSDPNRPT--RGIRWKSSP 494
Score = 139 bits (351), Expect = 7e-33
Identities = 98/403 (24%), Positives = 161/403 (39%), Gaps = 29/403 (7%)
Query: 274 TRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSR 333
+R RP S SPRR G + H +RN + R R R+ + R
Sbjct: 27 SRRRPGSQE---SPRRRGLG---QAHKDADGDDRERNRQKERERRRE---KRQTERETDR 77
Query: 334 SHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSG 393
+ + +++ R R R R +ER R +E++ +E+ R
Sbjct: 78 KRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER 137
Query: 394 SPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR 453
++Q D R R + ++ R R + R R R+ K R+ ++R + R+R R +
Sbjct: 138 GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
Query: 454 SPNKARDHSRSRSPNKARDRS------RSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
NK D R + R+R R R +ERD + +ER+ + R + ER
Sbjct: 198 E-NKTEDRHSERGRERERERETETETERKRQTDRERDRQR--KTEREREKQAERERASER 254
Query: 508 QCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKER 567
+ + + +ERD R R RQ+ + R +++R R R ER+ + R +ER
Sbjct: 255 ETERDKERERERDRDRDRD---RRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
Query: 568 DRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEG 627
+R R R +ERER + R ERD + R R R E R+R +EG
Sbjct: 312 ERNRKRERERERERERERQRETERDREKER--------ERKRKRQTEMDRERNRQTGREG 363
Query: 628 NHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSK 670
R +E + + + + +R R + R K
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
Score = 138 bits (347), Expect = 2e-32
Identities = 97/409 (23%), Positives = 156/409 (38%), Gaps = 18/409 (4%)
Query: 271 QASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHS 330
Q R + R R R +++ R R +R R + R R+ + +
Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE 118
Query: 331 QSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRS 390
+ R+ K + + R RGR +ER + ++ D + +
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 391 QSGSPNKQRDHSRSR---SPNKARDRSRSRSPYKARDR------SRSRSPNKARDCSR-- 439
+ N+Q R R NK DR R + R+R R R ++ RD R
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 440 SRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRR 499
R K +R R+ RD R R ++ RDR R R +ER + ERD
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRET 297
Query: 500 SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQ 559
R ++R+ + R +++R+ R R +ERQR R KER+R + R +RE +
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
Query: 560 SRSPSKERDRRRWRSPSKERERRQSRSSSE-ERDHSRSRSPNKQSGYSRPRASSKEKAHS 618
R R R +ER+R+ +R E ERD R R ++ + R +E
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 619 RSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRT 667
R R +E + R +E R D +R R + + R+
Sbjct: 418 REREKDRESERGRERGREREKQKG-----RERDRERQTDRQAGRQRKRS 461
Score = 77.8 bits (190), Expect = 3e-14
Identities = 52/215 (24%), Positives = 91/215 (42%), Gaps = 9/215 (4%)
Query: 472 DRSRSRSPSKERDHSQ-LGSPSKERD---HRRSRSPSKERQCRQSRSSSKERDHRRSRSP 527
D SR R S+E + LG K+ D R+R +ER+ R+ R + +E D +R R
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRR 83
Query: 528 SKERQRRQSRSPNKERDRSQSRSPSEEREH----RQSRSPSKERDRRRWRSPSKERERRQ 583
K+R R++ R ++RDR + R +RE + R+ KER+R R + R+R+
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
Query: 584 SRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQ 643
ER + +Q+ R R + + + R R +++ + R KE+
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Query: 644 STVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPST 678
R + +R + + R + T
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKT 238
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 141 bits (356), Expect = 2e-33
Identities = 102/314 (32%), Positives = 154/314 (49%), Gaps = 21/314 (6%)
Query: 328 RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSS----- 382
R + + K ++ R R RS + R+ S RS SRS S R+ GSSS
Sbjct: 236 RPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDREL 295
Query: 383 -PRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRS-PNKARDCSRS 440
KE R + + ++++ RSRS ++ +R RSRS + R RSRSR RD R
Sbjct: 296 EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE 355
Query: 441 RSPYKARDRSRSRSPNKARDHSRSRSPNKARDRS---RSRSPSKERDHSQLGSPSKERDH 497
R R R R R +K R + R + ++R+RS RSR +E+ H + + RD
Sbjct: 356 REKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDD 415
Query: 498 RRSRSPSKERQCRQSRSSSKERDHR---RSRSPSKERQRRQSRSPNKERDRSQSRSPSEE 554
+R K + SRS S+ER HR RSR+ K + R +K ++ S+ +S
Sbjct: 416 KRDSKKEK----KHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRS 471
Query: 555 REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG--YSRPRASS 612
R Q R+ S E+ ++R SPSKE+ R++SR S+ER H R S +K + R R+ S
Sbjct: 472 RSGSQGRTDSVEKSKKREHSPSKEKSRKRSR--SKERSHKRDHSDSKDQSDKHDRRRSQS 529
Query: 613 KEKAHSRSRTPSKE 626
E+ + +K+
Sbjct: 530 IEQESQEKQHKNKD 543
Score = 138 bits (347), Expect = 2e-32
Identities = 110/323 (34%), Positives = 160/323 (49%), Gaps = 43/323 (13%)
Query: 275 RSRPQSHSQSRSPRRSRSGSQKRTHSRV--RSHSWKRNHSRARSRTRKGILSQMGRHSQS 332
R R +S +S SPRRS S+ R+H R S S+ R R + R R + R ++
Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQR------LEREAKE 310
Query: 333 RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK---ESGR 389
R + +S++ R R RS S+ER S SRS ++ D R R+ E GR
Sbjct: 311 REKERRRSRSIDRGLERRRSR------SRERHRSRSRSRDRKGDRRDRDREREKENERGR 364
Query: 390 SQSGSPNKQRDHSRSRSPNKARDRS---RSRSPYKARDRSRSRSPNKARDCSRSRSPYKA 446
+ +K+R + R + ++R+RS RSR + + + + RD R K
Sbjct: 365 RRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424
Query: 447 RDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKE 506
RSRSR K R SRSR+ K RSRSRS K H + SKE+ ++RSRS S
Sbjct: 425 HSRSRSRE-RKHRSRSRSRNAGK---RSRSRSKEKSSKHK---NESKEKSNKRSRSGS-- 475
Query: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKE 566
Q R+ S E+ +R SPSKE+ R++SRS KER S +R+H S+ S +
Sbjct: 476 ----QGRTDSVEKSKKREHSPSKEKSRKRSRS--KER--------SHKRDHSDSKDQSDK 521
Query: 567 RDRRRWRSPSKERERRQSRSSSE 589
DRRR +S +E + +Q ++ E
Sbjct: 522 HDRRRSQSIEQESQEKQHKNKDE 544
Score = 130 bits (328), Expect = 3e-30
Identities = 98/317 (30%), Positives = 161/317 (50%), Gaps = 20/317 (6%)
Query: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
K D + + PRK + G+ R R RS + R S RSP ++R RS R +
Sbjct: 227 KNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGH 286
Query: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPS 492
+ R K R R + + ++ RSRS ++ +R RSRS + R S+ S
Sbjct: 287 GSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSR----S 342
Query: 493 KERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPS 552
++R R R +ER+ R ++RD+ + R +E++R +SR +KE+ +SR
Sbjct: 343 RDRKGDR-RDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQ---RSRGEV 398
Query: 553 EEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASS 612
EE++H++ + + RD +R ++E++ SRS S ER H RSRS ++ +G R R+ S
Sbjct: 399 EEKKHKEDKDDRRHRDDKR----DSKKEKKHSRSRSRERKH-RSRSRSRNAG-KRSRSRS 452
Query: 613 KEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTS 672
KEK+ S+ + SKE ++ +SR+ S+ S V +S + SP++ S+ R+ SK
Sbjct: 453 KEKS-SKHKNESKEKSNKRSRSGSQGRTDS---VEKSKKREHSPSKEK--SRKRSRSKER 506
Query: 673 SHSPSTFPSGGQTLSQD 689
SH S Q+ D
Sbjct: 507 SHKRDHSDSKDQSDKHD 523
Score = 124 bits (311), Expect = 3e-28
Identities = 103/319 (32%), Positives = 148/319 (46%), Gaps = 40/319 (12%)
Query: 226 PSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR 285
P + S SP SR SR SS + + R R + ++ R
Sbjct: 263 PRRSLSPRRSPRRSR-----------SRSHHREGHGSSSFDRELEREKERQRLEREAKER 311
Query: 286 SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR 345
R RS S R R RS S +R+ SR+RSR RKG R + + + R
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKG---------DRRDRDREREKENER 362
Query: 346 TPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSR 405
RR R ++ R +E+ SR SKE+ RG +K + + RD R
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHK---EDKDDRRHRDDKRDS 419
Query: 406 SPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSR 465
K RSRSR K R RSRSR+ K SRSRS K+ S+ N++++ S R
Sbjct: 420 KKEKKHSRSRSRER-KHRSRSRSRNAGKR---SRSRSKEKS-----SKHKNESKEKSNKR 470
Query: 466 SPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD--HRR 523
S + ++ R+ S SK+R+HS PSKE+ +RSR SKER ++ S SK++ H R
Sbjct: 471 SRSGSQGRTDSVEKSKKREHS----PSKEKSRKRSR--SKERSHKRDHSDSKDQSDKHDR 524
Query: 524 SRSPSKERQRRQSRSPNKE 542
RS S E++ ++ + NK+
Sbjct: 525 RRSQSIEQESQEKQHKNKD 543
Score = 119 bits (299), Expect = 7e-27
Identities = 90/292 (30%), Positives = 143/292 (48%), Gaps = 35/292 (11%)
Query: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
+ R R S SPR+ RS+S S +++ S S R++ R R +A++R + R
Sbjct: 259 RSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERR-- 316
Query: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK-----ARDRSRSRSPSKE----- 482
RSRS + +R RSRS R+ RSRS ++ RDR R R E
Sbjct: 317 ------RSRSIDRGLERRRSRS----RERHRSRSRSRDRKGDRRDRDREREKENERGRRR 366
Query: 483 -RDHSQLGSPSKERDHRRSRSPSKERQCR---QSRSSSKERDHRR----SRSPSKERQRR 534
RD+ + +E++ RSR SKE++ R + + +++D RR R KE++
Sbjct: 367 DRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHS 426
Query: 535 QSRS-PNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDH 593
+SRS K R RS+SR+ + R SK ++ + +S + R Q R+ S E+
Sbjct: 427 RSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSK 486
Query: 594 SRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKE--GNHSQSRTSSKESDPSQ 643
R SP+K+ SR R+ SKE++H R + SK+ H + R+ S E + +
Sbjct: 487 KREHSPSKEK--SRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQE 536
Score = 111 bits (278), Expect = 2e-24
Identities = 87/270 (32%), Positives = 137/270 (50%), Gaps = 21/270 (7%)
Query: 439 RSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR 498
RSRSP ++ RS +++R H R + + DR R E++ +L +KER+
Sbjct: 259 RSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELER----EKERQRLEREAKEREKE 314
Query: 499 RSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHR 558
R RS S +R + RS S+ER RSRS ++ RR ++ER++ R +R++
Sbjct: 315 RRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR---DREREKENERGRRRDRDYD 371
Query: 559 QSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHS 618
+ R +E++R R R SKE ++SR EE+ H + + R S KEK HS
Sbjct: 372 KERGNEREKERERSRERSKE---QRSRGEVEEKKHKEDKDDRRHR--DDKRDSKKEKKHS 426
Query: 619 RSRT-PSKEGNHSQSRTSSKES---DPSQSTVPRSPDWKRSPTRTSSLSQNRT----PSK 670
RSR+ K + S+SR + K S +S+ ++ ++S R+ S SQ RT SK
Sbjct: 427 RSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSK 486
Query: 671 TSSHSPSTFPSGGQTLSQDDS-QADATTSK 699
HSPS S ++ S++ S + D + SK
Sbjct: 487 KREHSPSKEKSRKRSRSKERSHKRDHSDSK 516
Score = 82.8 bits (203), Expect = 1e-15
Identities = 75/272 (27%), Positives = 110/272 (40%), Gaps = 32/272 (11%)
Query: 472 DRSRSRSPSKERDHSQLGSPSKER--DHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSK 529
D+ P K + + G+ +R + RRSRSP + R+S S+ R H R S
Sbjct: 230 DQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSS 289
Query: 530 ERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRS-SS 588
R R KER R + + E+E R+SRS + +RRR RS + R R +SR
Sbjct: 290 SFDRELERE--KERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKG 347
Query: 589 EERDHSRSRSPNKQSG------YSRPRASSKEKAHSRSRTPSKE---------------- 626
+ RD R R + G Y + R + +EK RSR SKE
Sbjct: 348 DRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407
Query: 627 ---GNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTS-SLSQNRTPSKTSSH-SPSTFPS 681
+ R S KE S+S RS +R + S++R+ K+S H + S S
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKS 467
Query: 682 GGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
++ S + D+ S S K
Sbjct: 468 NKRSRSGSQGRTDSVEKSKKREHSPSKEKSRK 499
Score = 82.0 bits (201), Expect = 2e-15
Identities = 88/337 (26%), Positives = 140/337 (41%), Gaps = 34/337 (10%)
Query: 89 RTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRT- 147
R P V + ++ ++ + G R RR SRS +RS S +P R R+
Sbjct: 220 RIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSR 279
Query: 148 --HGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIG 205
H G +S R +++ R + + R R RS S R L ++
Sbjct: 280 SHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRR---------S 330
Query: 206 RSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPT-EMSS 264
RS E + S ++ + + + + R+ + Y + REK + E S
Sbjct: 331 RSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK 390
Query: 265 RVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILS 324
+S + + + R R +++ HSR RS +R H R+RSR+R
Sbjct: 391 EQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR--ERKH-RSRSRSRNA--- 444
Query: 325 QMGRHSQSRSHSKG-KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSP 383
G+ S+SRS K K +N+S+ RS RS S R+ S E+ + SP
Sbjct: 445 --GKRSRSRSKEKSSKHKNESKEKSNKRS----------RSGSQGRTDSVEKSKKREHSP 492
Query: 384 RKESGRSQSGSPNK--QRDHSRSRSPNKARDRSRSRS 418
KE R +S S + +RDHS S+ + DR RS+S
Sbjct: 493 SKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQS 529
Score = 81.6 bits (200), Expect = 2e-15
Identities = 79/326 (24%), Positives = 136/326 (41%), Gaps = 46/326 (14%)
Query: 186 SQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSY 245
++PR + K G I R E + S + +P P + +S + S+
Sbjct: 235 TRPRKIKKDGKE--GAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGS-SSF 291
Query: 246 GQMIIPSREKSYSPTEMSSRVKSYNQAST--------RSRPQSHSQSRSPRRSRSGSQK- 296
+ + +E+ E R K ++ + RSR + +SRS R R G ++
Sbjct: 292 DRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRD 351
Query: 297 ----------RTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHS---QSRSHSKGKSQNQ 343
R R R + +R + R + R R S+ R + + H + K +
Sbjct: 352 RDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRR 411
Query: 344 SRTPRRG--RSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDH 401
R +R + SR+ S+ER H SRS S+ R S +++S +K ++
Sbjct: 412 HRDDKRDSKKEKKHSRSRSRERKH-RSRSRSRNAGKRSRSRSKEKS--------SKHKNE 462
Query: 402 SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDH 461
S+ +S ++R S+ R+ + + R SP+K K+R RSRS+ + RDH
Sbjct: 463 SKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKE----------KSRKRSRSKERSHKRDH 512
Query: 462 SRSRSPNKARDRSRSRSPSKERDHSQ 487
S S+ + DR RS+S +E Q
Sbjct: 513 SDSKDQSDKHDRRRSQSIEQESQEKQ 538
Score = 51.6 bits (122), Expect = 3e-06
Identities = 63/249 (25%), Positives = 101/249 (40%), Gaps = 26/249 (10%)
Query: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
S+S +R +R RSR RS+ R R D K ++ R R RG
Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERG--RRRDRDYDKERG 375
Query: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
+ RS +RS + S G + + R R ++ + K + R R+ R
Sbjct: 376 NEREKERERSRERSKEQRSR-GEVEEKKHKEDKDDR-RHRDDKRDSKKEKKHSRSRSRER 433
Query: 182 E-RSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
+ RS S+ RN K+S RS E + SKEKS+ S S S
Sbjct: 434 KHRSRSRSRNAGKRSR--------SRSKEKSSKHKN---------ESKEKSNKRSRSGS- 475
Query: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQK-RTH 299
+ + S+++ +SP++ SR +S ++ + R S S+ +S + R SQ
Sbjct: 476 --QGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQE 533
Query: 300 SRVRSHSWK 308
S+ + H K
Sbjct: 534 SQEKQHKNK 542
Score = 32.0 bits (71), Expect = 2.1
Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 1/116 (0%)
Query: 25 DPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRV 84
D K + + S + +R + SRN+ S KS+ K + + RSR
Sbjct: 414 DDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473
Query: 85 RSKARTPSRVSTDTRTSKASK-ASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRA 139
S+ RT S + R SK S R + +H R + + S R S++
Sbjct: 474 GSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQS 529
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 137 bits (344), Expect = 5e-32
Identities = 170/713 (23%), Positives = 245/713 (34%), Gaps = 25/713 (3%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
SS SS S S S SS + +S + + + S +S +S S SS
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
S S S+ + S SS+S S S+D+ +S +S SD + S
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD-------SSDSSN 661
Query: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
+ S SS S S +S+ + + +S + S S +SN
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 182 ERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
SDS N S S S + S+ + S + SD+ S S
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS-- 779
Query: 242 VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSR 301
+ S + S S N + + + S S S S S ++S
Sbjct: 780 ---------SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 302 VRSHSWKRNHSRARSRTRKGILSQMGRHSQS--RSHSKGKSQNQSRTPRRGRSHNWSRNP 359
S S + S S + G S S S S S S + + + S + +
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 360 SKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419
S + S S + S S D SS S S S + D+S S + + D S S
Sbjct: 891 SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950
Query: 420 YKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSP 479
+ D S S + + D S S S D S S + + + D S S + + D S S
Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNS----SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006
Query: 480 SKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP 539
S D S + S + S + S S SS D S S S
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066
Query: 540 NKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSP 599
+ D S S S+ E S S D S + S SS+ D S S
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 600 NKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRT 659
+ S S SS S S S + S S SS SD S S+ S S +
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSD 1185
Query: 660 SSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
SS S + + S SS S + S + S D S + ++ + SS SS
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Score = 135 bits (340), Expect = 1e-31
Identities = 166/710 (23%), Positives = 259/710 (36%), Gaps = 40/710 (5%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
SS SK S + S SS +D K +S ++ ++ N + + S NS S S
Sbjct: 616 SSDSSDSKSDSSKSESDSS--DSDSKSDSSDSNSSDSSDNSD--SSDSSNSSNSSDSSDS 671
Query: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
S S+ S+S+ + ++ SS S S + + S S+D+ S +S +SD + S
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNS-SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSN 730
Query: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
+ S SS S S S+ + +S S S + +
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNS----------------SDSSDSSDSSNSSDSSDSSDSS 774
Query: 182 ERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
+ SDS + S S S SS+ + + ++ + S SD+ + S S
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 242 VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSR 301
+ S S ++ S+R S N S+ S S S + S S S + ++S
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSN--SSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 302 VRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSK 361
S S + S + S S S+S S++ + + S + + + S
Sbjct: 893 DSSDSSNSSDSDSSD-------SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945
Query: 362 ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYK 421
+ S S + S S +SS +S S S + D S S + + D S S +
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 422 ARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSK 481
+ D S S + + D S S + D S S + + D S S + + + S S S
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Query: 482 ERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNK 541
D S S D S S S SS D S S S + +
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125
Query: 542 ERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK 601
D S S S+ S S+ D S + S SS+ D S S +
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 602 QSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSS 661
S S SS S S S + S S SS SD S S S + SS
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS----------SDSNESS 1235
Query: 662 LSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
S + + S SS+S + S + S DS ++ + + G + S S
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285
Score = 114 bits (286), Expect = 2e-25
Identities = 157/690 (22%), Positives = 237/690 (34%), Gaps = 44/690 (6%)
Query: 54 NSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQ 113
N V +SKS ++++ P + S R K + R +K S+ V Q
Sbjct: 315 NEVDGDKTSKSEENSAG--IPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQ 372
Query: 114 RRGTHSRGRTPGRRG----------SRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTS 163
+G +G + G R + K G ++T G V
Sbjct: 373 DKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQG------EVVNIEGP 426
Query: 164 QQKGSRGKSYGRPRTSNRERSDSQPR-NLSKKSYR--PPGGSGIGRSSELAVTPS--TAK 218
QK G G T + SD + KS + P S ++ A + S +
Sbjct: 427 GQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSS 486
Query: 219 CQTPTGIPSKEKSDNPSPSSSRKVKS----------------YGQMIIPSREKSYSPTEM 262
+ S E DN + S S+ + G +KS S
Sbjct: 487 SRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGK 546
Query: 263 SSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI 322
S S + S+ S S S S S S + S S + S + + +
Sbjct: 547 SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606
Query: 323 LSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSS 382
S S S S KS S S + S++ S + + S S +S D SS+
Sbjct: 607 SSDSSDSSDSSDSSDSKS--DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664
Query: 383 PRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS 442
S S S + D S S + + D S S + D S S S + + + + S
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 443 PYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRS 502
+ + S S + + D S S + + D S S S D S S D S
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Query: 503 PSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRS 562
+ S SS D S S S S N D S S S+ S
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS-DSSNSSDSSDSSNSSDSSD 843
Query: 563 PSKERDRRRWRSPSKERERRQSRSS-SEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
S D S ++ S SS S + +S S + S S + S + ++S
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903
Query: 622 TPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPS 681
S N S S SS SD S+S+ S + S + SS S + + S SS S ++ S
Sbjct: 904 DSSDSSNSSDSSDSSNSSDSSESS-NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962
Query: 682 GGQTLSQDDSQADATTSKATLPGERSSSSS 711
+ S D + +D++ S + SS SS
Sbjct: 963 SNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Score = 113 bits (282), Expect = 7e-25
Identities = 150/673 (22%), Positives = 231/673 (34%), Gaps = 36/673 (5%)
Query: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGT 117
S S+S + S S + + K ++ S S + +S +S +SD +
Sbjct: 515 SDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574
Query: 118 HSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPR 177
+S + S + + + + S + +S K KS
Sbjct: 575 NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634
Query: 178 TSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP--- 234
S+ +SDS N S S + S+ + S + SD+
Sbjct: 635 DSD-SKSDSSDSNSSDSSDN---------------SDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 235 --------SPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRS 286
S SS S S + S S + SS + N + + S S S S
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Query: 287 PRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHS-----QSRSHSKGKSQ 341
S S ++S S S ++S S + S +S S S S
Sbjct: 739 NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798
Query: 342 NQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDH 401
N S + S + S + + S+S S+S + +SS +S S GS + +
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR 858
Query: 402 SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRS--RSPYKARDRSRSRSPNKAR 459
S S + + + D S S + + D S S + + D S S S + D S S + +
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 460 DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER 519
+ S S + + D S S S D S S D S S S SS
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS- 977
Query: 520 DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKER 579
D S S S + + S S S+ + S S D S
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKES 639
+ S SS+ D S S + + S S SS S S S+ + S S SS S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 640 DPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSK 699
D S S+ S S + SS S N + S SS S + S + S D S++ ++
Sbjct: 1098 DSSDSS-DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDS 1156
Query: 700 ATLPGERSSSSSS 712
+ SS SS
Sbjct: 1157 SDSSDSSDSSDSS 1169
Score = 54.3 bits (129), Expect = 4e-07
Identities = 82/369 (22%), Positives = 136/369 (36%), Gaps = 16/369 (4%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
SS +S S + + S +S ++D S S+ S+ + S + + S +S S S
Sbjct: 947 SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006
Query: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
S S+ S+ + + + SS S S + S S + +S +S +SD S
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD----------SSN 1056
Query: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
+ S SS S S S+ + + +S +S S S + +
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN----SSDSSDSSDSSDSSDSSDSS 1112
Query: 182 ERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
+ SDS + S S S SS + + +++ + S + S SS
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172
Query: 242 VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSR 301
S S + S S S S + S+ S S S S S S + S
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232
Query: 302 VRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSK 361
S S + S S + S S S S S +S +QS++ + + S + S+
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDS--SDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290
Query: 362 ERSHSHSRS 370
+HS S
Sbjct: 1291 GSDSNHSTS 1299
Score = 38.9 bits (89), Expect = 0.017
Identities = 71/363 (19%), Positives = 122/363 (33%), Gaps = 31/363 (8%)
Query: 370 SSSKERDHRGSSSPRKESGRSQSGSPN-KQRDHSRSRSPNKAR----DRSRSRSPYKARD 424
S E + G+ + + Q G + K+ DH S N D P+ D
Sbjct: 259 SGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVD 318
Query: 425 -----RSRSRSPNKARD--CSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDR---- 473
+S S D R K R R N+ S + + K++D+
Sbjct: 319 GDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEI 378
Query: 474 ----SRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSK 529
S +R+ +KE G+ KE + K Q + E ++S +K
Sbjct: 379 KGPSSGNRNITKEVGK---GNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNK 435
Query: 530 ERQRRQSRSPNKER-DRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSS 588
N + D S + + S S D S + R + +S
Sbjct: 436 VGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNS 495
Query: 589 EERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPR 648
+E + + S +K + + S + GN + + +SD +
Sbjct: 496 DESKDNGNGSDSKGA------EDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGK-SD 548
Query: 649 SPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSS 708
S D S + SS S + + S +S + S+ + S D S +D++ S + SS
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 709 SSS 711
SS
Sbjct: 609 DSS 611
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 125 bits (315), Expect = 1e-28
Identities = 144/532 (27%), Positives = 216/532 (40%), Gaps = 89/532 (16%)
Query: 252 SREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNH 311
S +K +P S K +++ + R +S S S SP + + + H R RS S KR H
Sbjct: 95 SHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRH 154
Query: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
S + ++++ R + K Q++SR PR+ H R PS+ +S S SR S
Sbjct: 155 SSSSPKSKR------------RDEKRHKKQSRSR-PRKSHRHRHHRCPSRSQS-SESRPS 200
Query: 372 SKERDHRGSS------SPRKESGRSQSGSPNKQRDHSRSRSPNK---------------- 409
S E HRG S S R+ S R + SR P++
Sbjct: 201 SCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITG 260
Query: 410 ---ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR---SPNKARDHSR 463
A D + R RS+ + D S S + RSR + SP+ SR
Sbjct: 261 SGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSR 320
Query: 464 SRSPNKARDRSRSRSPSKERDHS----QLGSPSKERDHRRSRSPSKE------------- 506
+ D S + S ++ L S+ R+ R +SP E
Sbjct: 321 ELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPST 380
Query: 507 ------RQCRQSRSSSKERDHRRS-RSPSKERQRR--QSRSPNKERDRSQSRSPSEEREH 557
+ C +S S + R S RSP+ R QSRS + E+ RS SRSPS +
Sbjct: 381 ARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEK-RSYSRSPSYSSKS 439
Query: 558 RQSRSPSKERDRRRWRS-----PSKERERRQSRSSSEERDHSRSR------SPNKQSGYS 606
+ PS+ RR S PS+ER+ + S S++R+ R+R SP ++
Sbjct: 440 GKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRD 499
Query: 607 RP------RASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTS 660
P R +S K PS + S S TSS S S + RS RS +R+
Sbjct: 500 SPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSR 559
Query: 661 SLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
S+ RT S +SS SPS G ++ S+ S++ + + + + S SS
Sbjct: 560 RRSRTRTSSSSSSRSPS---PGSRSRSRSRSRSRSRSRSQSRSYSSADSYSS 608
Score = 119 bits (298), Expect = 1e-26
Identities = 174/669 (26%), Positives = 264/669 (39%), Gaps = 95/669 (14%)
Query: 1 MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPS 60
M+S ++ K G+ A P+P + + + S T + L T+P N V+
Sbjct: 1 MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVA--SITARKPLPRTEP--QNNPVVPAQ 56
Query: 61 SSKSTK-----------STSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDV 109
S K + S +R + R +R S + + K K
Sbjct: 57 DGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKST 116
Query: 110 RCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSR 169
R +RR + ++ +SSK+ R S + R + P R +K +
Sbjct: 117 RKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRR------DEKRHK 170
Query: 170 GKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKE 229
+S RPR S+R R P RP + C++ S E
Sbjct: 171 KQSRSRPRKSHRHRHHRCPSRSQSSESRP------------------SSCESRHRGRSPE 212
Query: 230 KSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQA-----STRSRPQSHSQS 284
+ SR+ P + S P++ ++ Y A + S +++
Sbjct: 213 EGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ-PLQMLGYLSARGVITGSGSAADLFTKT 271
Query: 285 RSP-RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQ 343
SP SR SQ+ S S ARSR ++ + S S SK + N
Sbjct: 272 ASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQE-------KGSPSGGLSKSRELNS 324
Query: 344 SRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS--PNKQRDH 401
T G S S +K + +S+ R+ RG SP E + S P+ R
Sbjct: 325 GNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSS 384
Query: 402 SR---SRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKA 458
SRS + A RS S S SRS +P + ++SRS + RS SRSP+ +
Sbjct: 385 PMKGCSRSSSYASTRSSSHS-------SRSPNPRASPRYTQSRST-SSEKRSYSRSPSYS 436
Query: 459 RDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
S RSP RSR RSPS R SPS+ERD + S S++R+ ++R
Sbjct: 437 -SKSGKRSPPSRSSRSR-RSPSYSRY-----SPSRERDPKYSEKDSQQRERERARR---- 485
Query: 519 RDHRRSRSPSKERQRRQSRSPNKERDRSQSR---------SPS-----EEREHRQSRSPS 564
RRS SP ++R RR S S + R + +R SPS S S S
Sbjct: 486 --RRRSYSPMRKR-RRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSS 542
Query: 565 KERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624
+ R RS S+ R RR+SR+ + SRS SP +S SR R+ S+ ++ S+SR+ S
Sbjct: 543 RSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS-RSRSRSRSRSRSRSQSRSYS 601
Query: 625 KEGNHSQSR 633
++S +R
Sbjct: 602 SADSYSSTR 610
Score = 113 bits (283), Expect = 5e-25
Identities = 153/515 (29%), Positives = 215/515 (41%), Gaps = 96/515 (18%)
Query: 228 KEKSDNPSPSSSRKVKSYGQ-----MIIPSREKSYSPTEMSSRVKSYNQASTRSRPQS-- 280
+ S +PSP +K KS + R S S + R + ++ +RSRP+
Sbjct: 122 RSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSH 181
Query: 281 -HSQSRSPRRSRSG--------SQKRTHSRVRSHSWKRNHSRARSRT------------- 318
H R P RS+S S+ R S +R HSR S+T
Sbjct: 182 RHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRP 241
Query: 319 ------RKGILSQMGRHSQSRSHSKGKSQNQSR-TPRRGRSHNW------SRNPSKERSH 365
G LS G + S S + ++ S T RGRS + S PS + S
Sbjct: 242 PSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSS 301
Query: 366 SHSRSSSKERDHRGSSSPRK-------ESGRS-QSGSPNKQRDHSRSRSPNKARDRSRS- 416
+ SR K G S R+ +SG S + SP + + SP SR
Sbjct: 302 ARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGF 361
Query: 417 RSPYK--ARDRSRSRSPNKARD-----CSRSRSPYKARDRSRS-RSPNKARD--HSRSRS 466
+SP A + S P+ AR CSRS S R S S RSPN +++SRS
Sbjct: 362 QSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRS 421
Query: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRS-----PSKERQCRQSRSSSKERDH 521
+ + RS SRSPS + PS+ RRS S PS+ER + S S++R+
Sbjct: 422 TSSEK-RSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRER 480
Query: 522 RRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRR-RWRSPSKERE 580
R+R +RR+S SP ++R R SPS H ++R + R R + PS
Sbjct: 481 ERAR------RRRRSYSPMRKRRRD---SPS----HLEARRITSARKRPIPYYRPSPSSS 527
Query: 581 RRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD 640
S +SS +S S S + YSR R+ S+ + SR +RTSS S
Sbjct: 528 GSLSSTSSW---YSSSSSRSASRSYSRSRSRSRSRRRSR------------TRTSSSSSS 572
Query: 641 PSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHS 675
S S RS RS +R+ S SQ+R+ S S+S
Sbjct: 573 RSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYS 607
Score = 76.3 bits (186), Expect = 9e-14
Identities = 93/319 (29%), Positives = 142/319 (44%), Gaps = 40/319 (12%)
Query: 11 SMSLAPSGSSMPTADPKPPASLKSTKSATPN--RSLVPTKP----ATSRNSVMSPSSSKS 64
S + + SG+S T+ P+ ++ S T S P A + S + PS+++S
Sbjct: 324 SGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARS 383
Query: 65 TKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTP 124
+ R+ S+ S+RS S +R+P+ ++ T S +S+ R + R ++S
Sbjct: 384 SPMKGCSRS-SSYASTRSSSHS-SRSPNPRASPRYTQSRSTSSEKRSYSRSPSYS----- 436
Query: 125 GRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERS 184
S+S KRSP S+ R R+ SR R P +K S+ + R R R RS
Sbjct: 437 ----SKSGKRSPPSRSSRSR-RSPSYSRYSPSRERDPKYSEKDSQQRE--RERARRRRRS 489
Query: 185 DSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKS 244
S R + S S L T+ + P IP PSPSSS + S
Sbjct: 490 YSPMRKRRRDS-----------PSHLEARRITSARKRP--IPYYR----PSPSSSGSLSS 532
Query: 245 YGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPR---RSRSGSQKRTHSR 301
S +S S + SR +S ++ +R+R S S SRSP RSRS S+ R+ SR
Sbjct: 533 TSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSR 592
Query: 302 VRSHSWKRNHSRARSRTRK 320
RS S + + + S TR+
Sbjct: 593 SRSQSRSYSSADSYSSTRR 611
Score = 32.7 bits (73), Expect = 1.2
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 9/99 (9%)
Query: 4 PKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSK 63
P SS S+S S SS ++ AS ++S + +RS ++ TS S SSS+
Sbjct: 522 PSPSSSGSLS---STSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTS-----SSSSSR 573
Query: 64 STKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSK 102
S S R+ S R SRSR RS++R+ S + + T +
Sbjct: 574 SPSPGSRSRSRS-RSRSRSRSRSQSRSYSSADSYSSTRR 611
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 123 bits (309), Expect = 5e-28
Identities = 173/716 (24%), Positives = 279/716 (38%), Gaps = 80/716 (11%)
Query: 46 PTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASK 105
P P T + P S S S + AP NR + P + +
Sbjct: 108 PWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQ 167
Query: 106 ASDVRCHQRRGTHSRGRTPG----------RRGSRSSKRSPSRASTPGRIRTHGARPGMA 155
+ G H PG RR SS R R+ ++ +
Sbjct: 168 HGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAV 227
Query: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPP----GGSGIG------ 205
R P ++G + + +ER + Q LSKK + GG G
Sbjct: 228 KRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSK 287
Query: 206 -------RSSELAVTPSTAKC-QTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKS- 256
+E S+ K ++P+ +P +E SD P + + K Y M++ +
Sbjct: 288 FDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSD---PEMTEEEKEYQMMLLTKMLLTE 344
Query: 257 ----YSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSR---------SGSQKRTHSRVR 303
+ E+ K ++ +T++ + +QS + SG + S
Sbjct: 345 ILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG 404
Query: 304 SHSWKRNHSRARSRTR-KGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNW------- 355
S S + R R R K Q H K + + +T R + N
Sbjct: 405 SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQN 464
Query: 356 SRNPSKERSHSHSRSSSKERDHRGSSS---PRKE------SGRSQSGSPNKQRDHSRSRS 406
S + + R + K+R ++S P+KE GRS+SGS + S SR+
Sbjct: 465 SLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRT 524
Query: 407 PNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRS 466
+ + S S S S S +R SRS SP + + SRSRSP SRSRS
Sbjct: 525 SSTSSTVSSS---------SYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRS 575
Query: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER-DHRRSR 525
++ +R+ K RD + S ER+ RR+RSPS+ER R+SRS S++R +R SR
Sbjct: 576 YSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER--RRSRSRSRDRRTNRASR 633
Query: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQ-S 584
S S++R++ + N + + + ++E+E ++ RS S ++DR++ KERER Q
Sbjct: 634 SRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKK---KDKEREREQDK 690
Query: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS 644
R ++R+ + ++ R R S E+ SRS + S + SR SK+S S
Sbjct: 691 RKEKQKREEKDFKFSSQDDRLKRKRES--ERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748
Query: 645 TVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700
D + S S +K HS S Q + S+ + S++
Sbjct: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
Score = 115 bits (287), Expect = 2e-25
Identities = 101/349 (28%), Positives = 165/349 (47%), Gaps = 34/349 (9%)
Query: 278 PQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSK 337
P + P++ +K+ SR S S + S +R+ + +S S S S S
Sbjct: 486 PNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVS-----SSSYSSSS 540
Query: 338 GKSQNQSRT--PRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSP 395
G S+ SR+ P+R + H+ SR+P+ + S SRS S+ + + K R +S
Sbjct: 541 GSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRN 600
Query: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP 455
+ +R+ R+RSP++ R RSRSRS RDR +R+ SRSR K D+ + S
Sbjct: 601 SIERERRRNRSPSRERRRSRSRS----RDRRTNRASR-----SRSRDRRKIDDQRGNLSG 651
Query: 456 NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRS- 514
N + ++ + ++RSRS +++ K+++ R + KE+Q R+ +
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDKDRKK---------KDKEREREQDKRKEKQKREEKDF 702
Query: 515 SSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR--SPSKERDRRRW 572
+D R R ER +S S + + R SR S++ + S+ S S R
Sbjct: 703 KFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSS 762
Query: 573 RSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
SP +E++ +++ HSRSRS K S S +AS K K+ SRSR
Sbjct: 763 ESPGSSKEKK-----AKKPKHSRSRSVEK-SQRSGKKASRKHKSKSRSR 805
Score = 95.5 bits (236), Expect = 2e-19
Identities = 101/340 (29%), Positives = 151/340 (44%), Gaps = 45/340 (13%)
Query: 226 PSKEKSDNPSPSSSRK-VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQS 284
P KE + SR S G SR S S T SS SY+ +S SR + S+S
Sbjct: 495 PKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSS---SYSSSSGSSR--TSSRS 549
Query: 285 RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQS 344
SP+R K+ HSR RS + K SR+RS +R+ + + R + +
Sbjct: 550 SSPKR------KKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIE 603
Query: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGR------SQSGSPNKQ 398
R RR RS PS+ER S SRS + R +R S S ++ + + SG+ +K
Sbjct: 604 RERRRNRS------PSRERRRSRSRSRDR-RTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656
Query: 399 RDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS---PYKARDRSRSRSP 455
+ ++ + K R RS + K +D+ R R +K ++ + + ++D R
Sbjct: 657 KGEAKEQERKKERSRSIDKD-RKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKR 715
Query: 456 NKARDHSRSRSPNKARDRSRSRSPSKE------RDHSQLGSPSKERDHRRSRSPSKERQC 509
R SRS S + R SR SK+ + HS GS S R S SKE++
Sbjct: 716 ESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHS--GSDSSGRSSSESPGSSKEKK- 772
Query: 510 RQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
+K+ H RSRS K QR ++ K + +S+SR
Sbjct: 773 ------AKKPKHSRSRSVEKS-QRSGKKASRKHKSKSRSR 805
Score = 87.8 bits (216), Expect = 3e-17
Identities = 92/339 (27%), Positives = 143/339 (42%), Gaps = 21/339 (6%)
Query: 175 RPRTSNRERSDSQPRNLSKKSYRP----PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEK 230
+ RT N S +P+ K+ + G S G SS + T ST+ + + S
Sbjct: 482 KKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSG 541
Query: 231 SDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRS 290
S S SS + SR +S + SR +SY++ ++ + R RRS
Sbjct: 542 SSRTSSRSSSPKRKKRH----SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRS 597
Query: 291 RSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRG 350
S +R R RS S +R SR+RSR R+ R S+SRS + K +Q R G
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRR-----TNRASRSRSRDRRKIDDQ-RGNLSG 651
Query: 351 RSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA 410
SH + +KE+ RS S ++D + KE R Q KQ+ + +
Sbjct: 652 NSHK-HKGEAKEQERKKERSRSIDKDRKKKD---KEREREQDKRKEKQKREEKDFKFSSQ 707
Query: 411 RDR-SRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK 469
DR R R + RS S S R SR S S+ S + + S S SP
Sbjct: 708 DDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGS 767
Query: 470 ARDRSRSRSPSKERDHS-QLGSPSKERDHRRSRSPSKER 507
++++ +++ P R S + S ++ R+ +S S+ R
Sbjct: 768 SKEK-KAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 72.8 bits (177), Expect = 1e-12
Identities = 93/361 (25%), Positives = 140/361 (38%), Gaps = 42/361 (11%)
Query: 36 KSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVS 95
K TPN + +P S+S S+S + ++R SS S S + S S
Sbjct: 482 KKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSS-S 540
Query: 96 TDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMA 155
+RTS S + +R+ HSR R+P + RS RS SR RI+ +
Sbjct: 541 GSSRTSSRSSSP-----KRKKRHSRSRSPTIKARRSRSRSYSR-----RIKIE------S 584
Query: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPS 215
+R R ++ S S R R NR S + R+ S+ R + RS +
Sbjct: 585 NRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD------ 638
Query: 216 TAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR 275
++ D S K G+ R+K S + R K +
Sbjct: 639 -----------RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
Query: 276 SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSH 335
+ Q R + + SQ R R +R SR+ S + K I+ R +S
Sbjct: 688 QDKRKEKQKREEKDFKFSSQDDRLKRKRES--ERTFSRSGSISVK-IIRHDSRQDSKKST 744
Query: 336 SKGKSQNQSRTPRRGRSHNWSRNPSKE---RSHSHSRSSSKERDHR-GSSSPRKESGRSQ 391
+K S+ S + GRS + S SKE + HSRS S E+ R G + RK +S+
Sbjct: 745 TK-DSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSR 803
Query: 392 S 392
S
Sbjct: 804 S 804
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 123 bits (309), Expect = 5e-28
Identities = 173/716 (24%), Positives = 279/716 (38%), Gaps = 80/716 (11%)
Query: 46 PTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASK 105
P P T + P S S S + AP NR + P + +
Sbjct: 108 PWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQ 167
Query: 106 ASDVRCHQRRGTHSRGRTPG----------RRGSRSSKRSPSRASTPGRIRTHGARPGMA 155
+ G H PG RR SS R R+ ++ +
Sbjct: 168 HGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAV 227
Query: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPP----GGSGIG------ 205
R P ++G + + +ER + Q LSKK + GG G
Sbjct: 228 KRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSK 287
Query: 206 -------RSSELAVTPSTAKC-QTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKS- 256
+E S+ K ++P+ +P +E SD P + + K Y M++ +
Sbjct: 288 FDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSD---PEMTEEEKEYQMMLLTKMLLTE 344
Query: 257 ----YSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSR---------SGSQKRTHSRVR 303
+ E+ K ++ +T++ + +QS + SG + S
Sbjct: 345 ILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRG 404
Query: 304 SHSWKRNHSRARSRTR-KGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNW------- 355
S S + R R R K Q H K + + +T R + N
Sbjct: 405 SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQN 464
Query: 356 SRNPSKERSHSHSRSSSKERDHRGSSS---PRKE------SGRSQSGSPNKQRDHSRSRS 406
S + + R + K+R ++S P+KE GRS+SGS + S SR+
Sbjct: 465 SLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRT 524
Query: 407 PNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRS 466
+ + S S S S S +R SRS SP + + SRSRSP SRSRS
Sbjct: 525 SSTSSTVSSS---------SYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRS 575
Query: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER-DHRRSR 525
++ +R+ K RD + S ER+ RR+RSPS+ER R+SRS S++R +R SR
Sbjct: 576 YSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER--RRSRSRSRDRRTNRASR 633
Query: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQ-S 584
S S++R++ + N + + + ++E+E ++ RS S ++DR++ KERER Q
Sbjct: 634 SRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKK---KDKEREREQDK 690
Query: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS 644
R ++R+ + ++ R R S E+ SRS + S + SR SK+S S
Sbjct: 691 RKEKQKREEKDFKFSSQDDRLKRKRES--ERTFSRSGSISVKIIRHDSRQDSKKSTTKDS 748
Query: 645 TVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700
D + S S +K HS S Q + S+ + S++
Sbjct: 749 KKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
Score = 115 bits (287), Expect = 2e-25
Identities = 101/349 (28%), Positives = 165/349 (47%), Gaps = 34/349 (9%)
Query: 278 PQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSK 337
P + P++ +K+ SR S S + S +R+ + +S S S S S
Sbjct: 486 PNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVS-----SSSYSSSS 540
Query: 338 GKSQNQSRT--PRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSP 395
G S+ SR+ P+R + H+ SR+P+ + S SRS S+ + + K R +S
Sbjct: 541 GSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRN 600
Query: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP 455
+ +R+ R+RSP++ R RSRSRS RDR +R+ SRSR K D+ + S
Sbjct: 601 SIERERRRNRSPSRERRRSRSRS----RDRRTNRASR-----SRSRDRRKIDDQRGNLSG 651
Query: 456 NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRS- 514
N + ++ + ++RSRS +++ K+++ R + KE+Q R+ +
Sbjct: 652 NSHKHKGEAKEQERKKERSRSIDKDRKK---------KDKEREREQDKRKEKQKREEKDF 702
Query: 515 SSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR--SPSKERDRRRW 572
+D R R ER +S S + + R SR S++ + S+ S S R
Sbjct: 703 KFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSS 762
Query: 573 RSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
SP +E++ +++ HSRSRS K S S +AS K K+ SRSR
Sbjct: 763 ESPGSSKEKK-----AKKPKHSRSRSVEK-SQRSGKKASRKHKSKSRSR 805
Score = 95.5 bits (236), Expect = 2e-19
Identities = 101/340 (29%), Positives = 151/340 (44%), Gaps = 45/340 (13%)
Query: 226 PSKEKSDNPSPSSSRK-VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQS 284
P KE + SR S G SR S S T SS SY+ +S SR + S+S
Sbjct: 495 PKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSS---SYSSSSGSSR--TSSRS 549
Query: 285 RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQS 344
SP+R K+ HSR RS + K SR+RS +R+ + + R + +
Sbjct: 550 SSPKR------KKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIE 603
Query: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGR------SQSGSPNKQ 398
R RR RS PS+ER S SRS + R +R S S ++ + + SG+ +K
Sbjct: 604 RERRRNRS------PSRERRRSRSRSRDR-RTNRASRSRSRDRRKIDDQRGNLSGNSHKH 656
Query: 399 RDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS---PYKARDRSRSRSP 455
+ ++ + K R RS + K +D+ R R +K ++ + + ++D R
Sbjct: 657 KGEAKEQERKKERSRSIDKD-RKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKR 715
Query: 456 NKARDHSRSRSPNKARDRSRSRSPSKE------RDHSQLGSPSKERDHRRSRSPSKERQC 509
R SRS S + R SR SK+ + HS GS S R S SKE++
Sbjct: 716 ESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHS--GSDSSGRSSSESPGSSKEKK- 772
Query: 510 RQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
+K+ H RSRS K QR ++ K + +S+SR
Sbjct: 773 ------AKKPKHSRSRSVEKS-QRSGKKASRKHKSKSRSR 805
Score = 87.8 bits (216), Expect = 3e-17
Identities = 92/339 (27%), Positives = 143/339 (42%), Gaps = 21/339 (6%)
Query: 175 RPRTSNRERSDSQPRNLSKKSYRP----PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEK 230
+ RT N S +P+ K+ + G S G SS + T ST+ + + S
Sbjct: 482 KKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSG 541
Query: 231 SDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRS 290
S S SS + SR +S + SR +SY++ ++ + R RRS
Sbjct: 542 SSRTSSRSSSPKRKKRH----SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRS 597
Query: 291 RSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRG 350
S +R R RS S +R SR+RSR R+ R S+SRS + K +Q R G
Sbjct: 598 NRNSIERERRRNRSPSRERRRSRSRSRDRR-----TNRASRSRSRDRRKIDDQ-RGNLSG 651
Query: 351 RSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA 410
SH + +KE+ RS S ++D + KE R Q KQ+ + +
Sbjct: 652 NSHK-HKGEAKEQERKKERSRSIDKDRKKKD---KEREREQDKRKEKQKREEKDFKFSSQ 707
Query: 411 RDR-SRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK 469
DR R R + RS S S R SR S S+ S + + S S SP
Sbjct: 708 DDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGS 767
Query: 470 ARDRSRSRSPSKERDHS-QLGSPSKERDHRRSRSPSKER 507
++++ +++ P R S + S ++ R+ +S S+ R
Sbjct: 768 SKEK-KAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 72.8 bits (177), Expect = 1e-12
Identities = 93/361 (25%), Positives = 140/361 (38%), Gaps = 42/361 (11%)
Query: 36 KSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVS 95
K TPN + +P S+S S+S + ++R SS S S + S S
Sbjct: 482 KKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSS-S 540
Query: 96 TDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMA 155
+RTS S + +R+ HSR R+P + RS RS SR RI+ +
Sbjct: 541 GSSRTSSRSSSP-----KRKKRHSRSRSPTIKARRSRSRSYSR-----RIKIE------S 584
Query: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPS 215
+R R ++ S S R R NR S + R+ S+ R + RS +
Sbjct: 585 NRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD------ 638
Query: 216 TAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTR 275
++ D S K G+ R+K S + R K +
Sbjct: 639 -----------RRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKERERE 687
Query: 276 SRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSH 335
+ Q R + + SQ R R +R SR+ S + K I+ R +S
Sbjct: 688 QDKRKEKQKREEKDFKFSSQDDRLKRKRES--ERTFSRSGSISVK-IIRHDSRQDSKKST 744
Query: 336 SKGKSQNQSRTPRRGRSHNWSRNPSKE---RSHSHSRSSSKERDHR-GSSSPRKESGRSQ 391
+K S+ S + GRS + S SKE + HSRS S E+ R G + RK +S+
Sbjct: 745 TK-DSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSR 803
Query: 392 S 392
S
Sbjct: 804 S 804
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 120 bits (300), Expect = 6e-27
Identities = 148/521 (28%), Positives = 204/521 (39%), Gaps = 55/521 (10%)
Query: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
S S+ S K+ + R R R K R S S + + K V+ H+R + S
Sbjct: 160 SSSSASPPPKKKKKKKGGHR-RSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGS 218
Query: 122 RTPGRRGSRSSK---------RSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKS 172
R R SRSSK + +PGR R+H G +S + +S SR S
Sbjct: 219 RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGR-RSHRHSSG-SSHSPSLSSHYSDSRSPS 276
Query: 173 YGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSD 232
P+ + R R+ +S P GGSG G + + + D
Sbjct: 277 RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPD 336
Query: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
PS S R + + + +PT + + S RS P S + R+
Sbjct: 337 KPSSPSPR---------VRDKAAAAAPTPPA---RGKESPSPRSAPSSQGRG---GRAAG 381
Query: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRS 352
G+ +R R R + + S R R R+ R S SRS S+ +S + S + R
Sbjct: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGS-SRSLSRARSSSDSGSGRGAPG 440
Query: 353 HNWSRNPSKERSHSHSRSSSKERDHR---GSSSPRKESGRSQSGSPNKQRDHSRSRSPN- 408
P ER H +KER R S+SP + + G K S SRSP
Sbjct: 441 P--GPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGK----SSSRSPGP 494
Query: 409 KARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPN 468
R S SRSP K+R RS + P+ S SRSP + SR + HS + +
Sbjct: 495 HPRSWSSSRSPSKSRSRSAEKRPH-----SPSRSPSPKKPLSRDKDGEGRARHSEAEA-T 548
Query: 469 KARDRSRSRSP--SKERDHSQLGSPSKERDHRR------SRSPSKERQCRQSRSSSKERD 520
+AR RSRS SP + RD P + R+ SPS C S S+ R
Sbjct: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYST--RS 606
Query: 521 HRRSRSPSKERQRRQSRS-PNKERDRSQSRSPSEEREHRQS 560
H RS SP SRS + R RS SR+PS R S
Sbjct: 607 HSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSS 647
Score = 119 bits (298), Expect = 1e-26
Identities = 148/509 (29%), Positives = 204/509 (40%), Gaps = 74/509 (14%)
Query: 256 SYSPTEMSSRVKSYNQASTRSRPQSHSQ----SRSPRRSRSGSQKRTHSRVRSHSWKRNH 311
S SP + K +R + + S+ S SP R + S K+ H R RS S R
Sbjct: 163 SASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKK-HRRDRSDSGSRRK 221
Query: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
R RSR+ K + + + R H++ + R G SH+ S + S S SR S
Sbjct: 222 RRHRSRSSKCKRKEKNKEKK-RPHTESPGRRSHRHSS-GSSHSPSLSSHYSDSRSPSRLS 279
Query: 372 SKERDH-RGSSSPRKESGRSQS-------GSPNK-----QRDHSRSRSPNKAR---DRSR 415
K RD R + S R RS S GSP + QR + P A D+
Sbjct: 280 PKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPS 339
Query: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
S SP + RD++ + +P S SP A S+ R A R R + R RSR
Sbjct: 340 SPSP-RVRDKAAAAAPTPPARGKESPSPRSAPS-SQGRGGRAAGGAGRRRRRRRRRRRSR 397
Query: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKER---- 531
S + + R + P+ R RS S ++RSSS R + P E
Sbjct: 398 SSASAPRRRGRRRPRPAPPRGSSRSLS--------RARSSSDSGSGRGAPGPGPEPGSER 449
Query: 532 ------QRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR------RRW---RSPS 576
+R + R P R R S SPS R+ K R R W RSPS
Sbjct: 450 GHGGHGKRAKERPP---RARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPS 506
Query: 577 KERERRQSRSSSEERDHSRSRSPNKQS-------GYSRPRASSKEKAHSRSRTPSKEGNH 629
K R R S+E+R HS SRSP+ + G R R S E +R R+ S
Sbjct: 507 KSRSR-----SAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIR 561
Query: 630 SQSRTSSKESDPSQSTVPRS---PDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTL 686
+ R S +P + T R P ++ SP+ +SS + +++ S SPS S G
Sbjct: 562 KRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYS 621
Query: 687 SQDDSQADATTSKATLPG----ERSSSSS 711
S+ T S + P RSSS S
Sbjct: 622 SRSHGTRSRTRSPSRTPSPSYHSRSSSES 650
Score = 98.2 bits (243), Expect = 2e-20
Identities = 133/504 (26%), Positives = 194/504 (38%), Gaps = 67/504 (13%)
Query: 254 EKSYSPTEMSSRVKSYNQA--------STRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSH 305
E+ YS E+ +V ++ Q + RP H + +PR + ++
Sbjct: 76 EQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEGAEPGLEYAPFDDD 135
Query: 306 SWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSH 365
+ S R G ++ S S + + ++G H SR + S
Sbjct: 136 DGPVDCDCPASCYR----GHRGYRTKHWSSSSASPPPKKKKKKKG-GHRRSRKKRRLESE 190
Query: 366 SHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS-----RSPNKARDRSRSRSPY 420
SSS R + S + RS SGS K+R SRS + NK + R + SP
Sbjct: 191 CSCGSSSPLRKKKKSVKKHRRD-RSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPG 249
Query: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480
+ R S S + S S S + + RS SR K RD R ++ S SRSPS
Sbjct: 250 RRSHRHSSGSSH-----SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS---SGSRSPS 301
Query: 481 KERDHSQLGSP-----SKERDHRRSRSPSKERQ--CRQSRSSSKERDHRRSRSPSKERQR 533
S GSP S +R P + S S + RD + +P+ +
Sbjct: 302 PS-GGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG 360
Query: 534 RQSRSPNKERDRSQSRS----------PSEEREHRQSRSPSKERDRRRWRSPSKERERRQ 583
++S SP + SQ R R R+SRS + RR R P R
Sbjct: 361 KESPSP-RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGS 419
Query: 584 SRSSSEERDHSRSRS----------PNKQSGYSRPRASSKE---KAHSRSRTPSKEGNHS 630
SRS S R S S S P + G+ +KE +A S +PS +
Sbjct: 420 SRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGR 479
Query: 631 QSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQD- 689
+ K S S PRS RSP+++ S S + P HSPS PS + LS+D
Sbjct: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP-----HSPSRSPSPKKPLSRDK 534
Query: 690 --DSQADATTSKATLPGERSSSSS 711
+ +A + ++AT RS S S
Sbjct: 535 DGEGRARHSEAEATRARRRSRSYS 558
Score = 94.0 bits (232), Expect = 4e-19
Identities = 138/531 (25%), Positives = 189/531 (35%), Gaps = 61/531 (11%)
Query: 23 TADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRS 82
++ PP K K RS K SS K S K+ +R S S
Sbjct: 161 SSSASPPPKKKKKKKGGHRRSR--KKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGS 218
Query: 83 RVRSKARTPSRVSTDTRTSKASKASDVRCHQRRG-THSRG--RTPGRRGSRSSKRSPSRA 139
R + + R+ S +K K RR HS G +P S RSPSR
Sbjct: 219 RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRL 278
Query: 140 STPGRI--RTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTS--NRERSDS---QPRNLS 192
S R R G++ SR +P S G +G P+ + + +RS + +P +
Sbjct: 279 SPKHRDEGRKTGSQRSSGSRSPSP------SGGSGWGSPQRNGGSGQRSGAHGGRPGSAH 332
Query: 193 KKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPS 252
+P S R A P+ P ++PSP S+ + G
Sbjct: 333 SPPDKPSSPSPRVRDKAAAAAPT----------PPARGKESPSPRSAPSSQGRGGRAAGG 382
Query: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHS 312
+ + R R +S S + +PRR + R S S R S
Sbjct: 383 AGR--------------RRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
Query: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS 372
+ S + +G R H G + P R R + S +P +H R
Sbjct: 429 SSDSGSGRGAPGPGPEPGSERGHG-GHGKRAKERPPRARPASTSPSPG-----AHGRRGG 482
Query: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
E G SS R +S S ++ SRSRS K R S SRSP + SR +
Sbjct: 483 PE----GKSSSRSPGPHPRSWSSSRSPSKSRSRSAEK-RPHSPSRSPSPKKPLSRDKD-G 536
Query: 433 KARDCSRSRSPYKARDRSRSRSP-NKARDHSRSRSPNKARDRSRSR-----SPSKERDHS 486
+ R +AR RSRS SP K R S S + +R R PS S
Sbjct: 537 EGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSS 596
Query: 487 QLGSPSKERDHRRSRSPSKERQCRQSRS-SSKERDHRRSRSPSKERQRRQS 536
L S R H RS SP SRS ++ R SR+PS R S
Sbjct: 597 CLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSS 647
Score = 72.0 bits (175), Expect = 2e-12
Identities = 109/403 (27%), Positives = 156/403 (38%), Gaps = 47/403 (11%)
Query: 3 SPKRSSKPSMSLAPSGSSMPTADP-KPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
SP SS S S +PS S D + S +S+ S +P+ S + RN S
Sbjct: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
Query: 62 SKSTKSTSTKRAPSNRPSSRS-RVRSKA------------RTPSRVSTDTRTSKASKASD 108
+ +P ++PSS S RVR KA +PS S + + +A+
Sbjct: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
Query: 109 V------RCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPT 162
R +RR + S P RRG R + +P R S+ R + + R
Sbjct: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGP 441
Query: 163 SQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTP 222
+ GS R + +R+ +P S P G+ R P
Sbjct: 442 GPEPGSE-----RGHGGHGKRAKERPPRARPASTSPSPGAHGRRGG-----PEGKSSSRS 491
Query: 223 TGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHS 282
G + S + SPS SR + + PSR S SP + SR K R+R
Sbjct: 492 PGPHPRSWSSSRSPSKSRSRSAEKRPHSPSR--SPSPKKPLSRDK---DGEGRARHSEAE 546
Query: 283 QSRSPRRSRSGSQKRTHSR-VRSHSWKRNHSRARSR-------TRKGILSQMGRHSQSRS 334
+R+ RRSRS S R R S R + AR R + S + +RS
Sbjct: 547 ATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRS 606
Query: 335 HSKGKSQNQSRTPRRGRSH---NWSRNPSKERSHS-HSRSSSK 373
HS+ S S RSH + +R+PS+ S S HSRSSS+
Sbjct: 607 HSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSE 649
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 118 bits (295), Expect = 2e-26
Identities = 104/521 (19%), Positives = 235/521 (45%), Gaps = 48/521 (9%)
Query: 223 TGIPSKEKSDNPSPSSSRKVK----SYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRP 278
T P E++ +P + VK S + P +E++ SP E+ S K+ + A ++
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560
Query: 279 QSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKG 338
++S ++S ++ ++ + +S + + S A +++ + S + ++S + +K
Sbjct: 561 PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKS 620
Query: 339 KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQ 398
+ ++++P +S +++P+KE + S ++ S E++ S K ++++ SP K
Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK- 679
Query: 399 RDHSRSRSPNKARDRSRSRSPYKARD--RSRSRSPNKARDCSRSRSPYKARDRSRSRSPN 456
++SP KA ++SP KA+ + ++SP KA+ S + K+ ++++S
Sbjct: 680 -----AKSPVKA----EAKSPEKAKSPVKEEAKSPEKAK--SPVKEEAKSPEKAKSPVKE 728
Query: 457 KARDHSRSRSPNK--ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRS 514
+A+ +++SP K A+ +++SP K + +K +RSP+ ++ +++S
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA-DKFPEKAKS 787
Query: 515 SSKE--RDHRRSRSPSKERQRRQSRS-PNKERDRSQSRSPSEEREHRQSRSPSKERDRRR 571
KE + +++SP KE + + P KE +S + + +E + P K + +
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 572 WRSPSKERERRQSRSSSEERDHSRSR-SPNKQSGYSRPRAS----SKEKAHSRSRTPSKE 626
+P E ++ + + +++ + + K+ +P+ S KE+A + + P+ E
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907
Query: 627 GN-------------HSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSS 673
++ + KE D +++ P P K+ + + + + +
Sbjct: 908 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK-----EAAPEKKDTKEEKA 962
Query: 674 HSPSTFPSGGQTLSQDDSQADATTSKATL-PGERSSSSSSK 713
P P +DD SK E+SSS+ K
Sbjct: 963 KKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQK 1003
Score = 109 bits (273), Expect = 8e-24
Identities = 98/498 (19%), Positives = 236/498 (47%), Gaps = 40/498 (8%)
Query: 206 RSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSR 265
+S A +P + ++P + S EK+ +P+ + KS + P +E++ SP E+ S
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPA---KEEAKSPPEAKSPEKEEAKSPAEVKSP 581
Query: 266 VKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQ 325
K+ + A ++ S ++++SP +++S ++ S + S + +++ + + ++
Sbjct: 582 EKAKSPAKEEAK--SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK 639
Query: 326 MGRHSQSRSHSKGKS--QNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSP 383
+++S K KS + ++++P + +S + S E++ S ++ +K + + SP
Sbjct: 640 SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK--AKSP 697
Query: 384 RKESGRS--QSGSPNKQRDHS--RSRSPNK--ARDRSRSRSPYK--ARDRSRSRSPNKAR 435
KE +S ++ SP K+ S +++SP K A+ +++SP K A+ +++SP KA+
Sbjct: 698 VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK 757
Query: 436 --DCSRSRSPYKARDRSRS---RSPNKARDHSRS--RSPNKARDRSRSRS-------PSK 481
D + A++ +RS + P KA+ + +SP KA+ + + P K
Sbjct: 758 TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK 817
Query: 482 ERDHSQLGSPSKERDHRRSRSPSK--ERQCRQSRSSSKERDHRRSRSPSKERQR---RQS 536
E S + K ++ + P K E + + + +++D ++ +P KE + +
Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877
Query: 537 RSPNKERDRSQSRSPSEEREHRQSRSPSKERDR-RRWRSPSKERERRQSRSSSEERDHSR 595
+ P E+ + +E + + P+ E++ + + + ++ + +E D ++
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Query: 596 SRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRS 655
++ P+K + + ++ EK ++ K ++ +KE D + S P P +++
Sbjct: 938 AKEPSKP---AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKA 994
Query: 656 PTRTSSLSQNRTPSKTSS 673
+S+ ++ P + ++
Sbjct: 995 EKSSSTDQKDSKPPEKAT 1012
Score = 105 bits (263), Expect = 1e-22
Identities = 97/551 (17%), Positives = 243/551 (44%), Gaps = 51/551 (9%)
Query: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGR 122
+ TKS + A S ++S V+ +A++P+ + + +A ++V+ ++ +
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEK-EEAKSPAEVKSPEK------AK 551
Query: 123 TPGRRGSRS--SKRSPSR--ASTPGRIRT-HGARPGMASRVRTPTSQQKGSRGKSYGRPR 177
+P + ++S +SP + A +P +++ A+ ++P + + KS
Sbjct: 552 SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS----P 607
Query: 178 TSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPS 237
+S ++ ++ K+ + P +S E A +P+ + ++P S EK + SP
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEV---KSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPE 664
Query: 238 SSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKR 297
++ P + ++ SP + S VK+ ++ +++ +++SP +++S ++
Sbjct: 665 KAKS---------PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715
Query: 298 THSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQN----QSRTPRRGRSH 353
S ++ S + ++ + + + + +++S K K+ + +++TP + +
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775
Query: 354 NWS-RNPSKERSHSHSRSSSKERDHRGSSSPRKESGRS-QSGSPNKQRDHSRSRSPNKAR 411
+ + + P K +S S E+ + SP KE ++ + P K+ S + K +
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEK----AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831
Query: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR 471
+ P KA + +P + + K + + +P + + + K +
Sbjct: 832 EVKVKEPPKKAEEEKAPATPK-----TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886
Query: 472 DRSRSRSPSKERDHSQLGSPSKERDHR-RSRSPSKERQCRQSRSSSKERDHRRSRSPSKE 530
+ + D ++ +P KE + + +K ++ ++ + KE D +++ PSK
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE--KTEVAKKEPDDAKAKEPSKP 944
Query: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEE 590
+++++ K+ +++ P E+ ++ + +KE D+ + PSK + + +SSS
Sbjct: 945 AEKKEAAPEKKDTKEEKAKKPEEK---PKTEAKAKEDDKTLSKEPSKPKAEKAEKSSS-- 999
Query: 591 RDHSRSRSPNK 601
D S+ P K
Sbjct: 1000 TDQKDSKPPEK 1010
Score = 103 bits (257), Expect = 6e-22
Identities = 85/444 (19%), Positives = 200/444 (45%), Gaps = 27/444 (6%)
Query: 222 PTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
P G+P PS S+ KVKS ++ + EKS T + Q + +
Sbjct: 423 PEGLPKI-----PSVSTHIKVKSEEKIKVV--EKSEKETVIVEEQTEETQVTEEVTEEEE 475
Query: 282 SQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQ 341
+++ + + K + + K S + ++S + +K +
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEK 535
Query: 342 NQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDH 401
++++P +S +++P+KE + S + S E++ S + K +++S + + +
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 402 SRSRSPNKARD--RSRSRSPYKARD--RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNK 457
+ ++SP KA+ + ++SP +A+ + ++SP + + +++SP K ++SP K
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK----EEAKSPEK 651
Query: 458 AR--DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSS 515
A+ + ++SP KA+ ++ + S E+ S + + +K + +++SP KE ++
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE--KAKSPVKEEAKSPEKAK 709
Query: 516 SKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSP 575
S ++ +S +K + ++++P K + + + S E+ ++ + + ++P
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP 769
Query: 576 SKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS---RTPSKEGNHSQS 632
+KE R S ++ +++SP K+ S +A S K +++ P KE S
Sbjct: 770 AKEEAR-----SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 633 RTSSKESDPSQSTVPRSPDWKRSP 656
+ K + P+ + +++P
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAP 848
Score = 92.8 bits (229), Expect = 1e-18
Identities = 96/552 (17%), Positives = 225/552 (40%), Gaps = 55/552 (9%)
Query: 33 KSTKSATPNRSLVPTKPATS--RNSVMSPSSSKSTKSTSTKRAPSNRPS---SRSRVRSK 87
+ TKS + P K A S + SP+ +KS + K +P+ S ++S + +
Sbjct: 499 EETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK-SPAEVKSPEKAKSPAKEE 557
Query: 88 ARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRS--SKRSPSRASTPGRI 145
A++P + + +A ++V+ ++ ++P + ++S +SP +A +P +
Sbjct: 558 AKSPPEAKSPEK-EEAKSPAEVKSPEK------AKSPAKEEAKSPAEAKSPEKAKSPVKE 610
Query: 146 RTHG---ARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGG- 201
A+ + ++P + + KS + + E++ S + +K +
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPV 670
Query: 202 SGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTE 261
+S E A +P A+ ++P S K + SP ++ P +E++ SP +
Sbjct: 671 KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS---------PVKEEAKSPEK 721
Query: 262 MSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
S VK + +++ +++SP +++S + +T + ARS K
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK- 780
Query: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRN-PSKERSHSHSRSSSKERDHRGS 380
++S + KS ++++P + + + P KE S + K ++ +
Sbjct: 781 ----FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836
Query: 381 SSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRS 440
P+K +P + + +K + + +P + + + K ++
Sbjct: 837 EPPKKAEEEKAPATPKTEE-----KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891
Query: 441 RSPYKARDRSRSRSPNK-----------ARDHSRSRSPNKARDRSRSRSPSKERDHSQLG 489
+A D+ + +P K A+ ++ K D ++++ PSK + +
Sbjct: 892 AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA 951
Query: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
K+ +++ P ++ + + + +KE D S+ PSK + + +S D+ S+
Sbjct: 952 PEKKDTKEEKAKKPEEKPK---TEAKAKEDDKTLSKEPSKPKAEKAEKS--SSTDQKDSK 1006
Query: 550 SPSEEREHRQSR 561
P + E + ++
Sbjct: 1007 PPEKATEDKAAK 1018
Score = 75.9 bits (185), Expect = 1e-13
Identities = 100/552 (18%), Positives = 214/552 (38%), Gaps = 92/552 (16%)
Query: 1 MSSPKRSSKPSMSLA---PSGSSMPTADPKPPASLKSTKSATPNRSLVPTK-PATSRNSV 56
+ SP+++ P+ A P S + K PA +KS P ++ P K A S
Sbjct: 544 VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS-----PEKAKSPAKEEAKSPAEA 598
Query: 57 MSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRG 116
SP +KS K + ++S V+ +A++P+ V + + +K +
Sbjct: 599 KSPEKAKS----PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK-------EEAK 647
Query: 117 THSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGS--RGKSYG 174
+ + ++P + +SP +A +P ++ P + ++P + S + KS
Sbjct: 648 SPEKAKSP----EKEEAKSPEKAKSP--VKAEAKSP---EKAKSPVKAEAKSPEKAKSPV 698
Query: 175 RPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNP 234
+ + E++ S + +K + E A TP AK S EK+ +P
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSPEKAK-----SPVKEEAKTPEKAKSPVKEEAKSPEKAKSP 753
Query: 235 SPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGS 294
+ + VKS + P++E++ SP + + P +++S
Sbjct: 754 EKAKTLDVKS-PEAKTPAKEEARSPAD-----------------------KFPEKAKSPV 789
Query: 295 QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHN 354
++ S ++ S + ++A K I + S + K + P++
Sbjct: 790 KEEVKSPEKAKSPLKEDAKA---PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK 846
Query: 355 WSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS 414
P E +++D + +P+KE +P + + + + K ++
Sbjct: 847 APATPKTE----------EKKDSKKEEAPKKE-------APKPKVEEKKEPAVEKPKESK 889
Query: 415 RSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRS 474
+A D+ + +P K ++ A+ + ++ K D ++++ P+K ++
Sbjct: 890 VEAKKEEAEDKKKVPTPEKEAP-AKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK 948
Query: 475 RSRSPSKERDHSQLGSP---------SKERDHRRSRSPSKERQCRQSRSSSKERDHRRSR 525
+ K+ + P +KE D S+ PSK + + +SSS D + S+
Sbjct: 949 EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSS--TDQKDSK 1006
Query: 526 SPSKERQRRQSR 537
P K + + ++
Sbjct: 1007 PPEKATEDKAAK 1018
Score = 53.5 bits (127), Expect = 7e-07
Identities = 40/210 (19%), Positives = 94/210 (44%), Gaps = 19/210 (9%)
Query: 504 SKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP 563
++E Q + + +E++ + +E + +E +S P+EE + +
Sbjct: 461 TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP---PAEEAASPEKEAK 517
Query: 564 SKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTP 623
S ++ + + +K E+ +++S +E + +++SP K+ S P A S EK ++S P
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS--P 575
Query: 624 SKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683
++ + ++++ +KE +SP S + ++P K + SP+ S
Sbjct: 576 AEVKSPEKAKSPAKEE-------------AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV 622
Query: 684 QTLSQDDSQADATTSKATLPGERSSSSSSK 713
+ ++ ++ + KA P + + S K
Sbjct: 623 KEEAKSPAEV-KSPEKAKSPTKEEAKSPEK 651
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 117 bits (293), Expect = 4e-26
Identities = 201/818 (24%), Positives = 299/818 (36%), Gaps = 131/818 (16%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATP-----NRSLVPTKPATSRNSV 56
SS + SS+ + S PK S K K A+ N+ + K + R+
Sbjct: 206 SSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDT 265
Query: 57 MSPSSSKSTKSTSTKRAPSNRPSSRSRV---RSKARTPSRVSTDTRTSKASKASDVRCHQ 113
+ +S S++ + P RP V R R V T K + + Q
Sbjct: 266 ---NEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQ 322
Query: 114 RRGTHSRGRTPGRRGS-------RSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQK 166
+ GR RG+ RS S S H R P S +K
Sbjct: 323 KPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEK 382
Query: 167 GSRGKSYGRPRTSN-RERSDSQ-PRNLSKKSY-------RPPGGSGIGRSSELAVTPSTA 217
S+G P +S ERS SQ R+ S Y R G R +
Sbjct: 383 WSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKG 442
Query: 218 KCQT---------------PTGIPSKEKSDNPSPSSSRKVKSYGQMIIPS-----REKSY 257
K Q P+ I S + S SS + +S + S R+ S
Sbjct: 443 KKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSK 502
Query: 258 SPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSW---KRNHSRA 314
S ++ S + ++ S RS+ S S SR RSR+ S+ +HSR RS S K H +
Sbjct: 503 SDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKR 562
Query: 315 RSRTRKGILSQMGRHSQSRSH----SKGKSQN-----------------QSRTPRRGRSH 353
S++ + SQ+ + ++ + +++N S P R +
Sbjct: 563 ASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPG 622
Query: 354 NWSRNPSKERSHSHSRSSSKERDHRGSSSPR--KESGRSQSGSPNKQRDHSRSRSPNKAR 411
PS ER ++ + + S KE+G S S ++ S + +K
Sbjct: 623 QKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYS 682
Query: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR 471
DRS SP RSRSRS SRSRS RS +RS + A HSRSRSP+
Sbjct: 683 DRSSESSP-----RSRSRS-------SRSRS----YSRSYTRSRSLASSHSRSRSPS--- 723
Query: 472 DRSRSRSPSKERDHSQ---------LGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR 522
SRS S +K DHSQ + S R RR RS K+ + SS
Sbjct: 724 --SRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTL 781
Query: 523 RSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRS-PSKERDRRRWRSPSKERER 581
S+ + R ++ R S SE+ + ++S KE+ + R+ +K+ +
Sbjct: 782 HSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKN 841
Query: 582 RQSRSSSEER---------------DHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKE 626
R S ER DH R+ S K+ Y+ + S+ + SK
Sbjct: 842 RGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKN 901
Query: 627 GNHSQS------RTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFP 680
+H S TS ES+ S+ + P K S +SL + K+S ST
Sbjct: 902 DSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSS--TNTSLPDDNGAWKSSKQRTSTSD 959
Query: 681 SGGQTLSQDDS----QADATTSKATLPGERSSSSSSKL 714
S G + +++ Q SK L E + KL
Sbjct: 960 SEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKL 997
Score = 85.5 bits (210), Expect = 2e-16
Identities = 150/730 (20%), Positives = 280/730 (38%), Gaps = 93/730 (12%)
Query: 29 PASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS------KSTKSTSTKRAPSNRPSSRS 82
P+ ++S+KS+T + +SR+S +S S KS K + S+R S RS
Sbjct: 462 PSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRS 521
Query: 83 --------RVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKR 134
R S++RT S+ S+ +R+ S++S H++R + S +T + +
Sbjct: 522 KSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVK 581
Query: 135 SPSRASTPGRIRTHGARPGMASRVRT-PTSQQKG-SRGKSYGRPRTSNRERSDSQPRNLS 192
+ +T + +P +A + P S SR K +P + ER +
Sbjct: 582 TEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTT 641
Query: 193 -----KKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSS---SRKVKS 244
+ +Y G SS ++ T ++S SP S S + +S
Sbjct: 642 HLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRS 701
Query: 245 YGQMIIPSRE------KSYSPTEMSSRVKSYNQASTRSRPQSHSQ------SRSPRRSRS 292
Y + SR +S SP+ S Y+ S SR S++ R+ RR RS
Sbjct: 702 YSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRS 761
Query: 293 GSQKRT--HSRVRSHSWKRNHSR-ARSRTRKGILSQMGRHSQSRSHSKGKSQN-----QS 344
+K + H + S S K HS+ + R R + + S +S Q+ QS
Sbjct: 762 SGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQS 821
Query: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKE--SGRSQSGSPNKQRDHS 402
+ + + +E++ +S S+ KE S ++GS K+++++
Sbjct: 822 AQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYA 881
Query: 403 RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHS 462
S+ +++ + R + N D S + S S S
Sbjct: 882 GSKWDSES-------------NSERDVTKNSKNDSHPSSDKEEGEATSDSES-------E 921
Query: 463 RSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSS-SKERDH 521
S K + ++S + + D + SK+ R+ + E C S ++ K + H
Sbjct: 922 VSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQ----RTSTSDSEGSCSNSENNRGKPQKH 977
Query: 522 RRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERER 581
+ SKE +R+ KE+ + + ++++H+ K + W+ P + E
Sbjct: 978 KHG---SKENLKREHTKKVKEKLKGK-----KDKKHK----APKRKQAFHWQPPLEFGEE 1025
Query: 582 RQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDP 641
+ EE D + +K+ S + K+ ++ S+E + T + SD
Sbjct: 1026 EE-----EEIDDKQVTQESKEKKVSENNETIKDNI-LKTEKSSEEDLSGKHDTVTVSSDL 1079
Query: 642 SQSTVPRSPDWKRSPTRTS-SLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKA 700
Q T D K S + T+ + +N + H + P+G + + Q D + T
Sbjct: 1080 DQFT---KDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDR 1136
Query: 701 TLPGERSSSS 710
+ P + +S
Sbjct: 1137 SSPAKVEETS 1146
Score = 81.3 bits (199), Expect = 3e-15
Identities = 89/307 (28%), Positives = 129/307 (42%), Gaps = 46/307 (14%)
Query: 164 QQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPT 223
Q S + T +E ++ NL K ++P G G ++ A T S + + T
Sbjct: 1194 QDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVG-NLAAPNAATSSAVEVKVLT 1252
Query: 224 GIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQ--SH 281
+P + S+ G + R+ + ++ R ++ +S P
Sbjct: 1253 TVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTA----RLNRRPRNQESSSDEQTPSRDDD 1308
Query: 282 SQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQ 341
SQSRSP RSRS S+ ++ R RS S+ + SR+RS T S
Sbjct: 1309 SQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSST---------------------SS 1347
Query: 342 NQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDH 401
+SR+ R RS W S+ R+ S S S + HR SS R RS S P H
Sbjct: 1348 YRSRSYSRSRSRGWY---SRGRTRSRSSSYRSYKSHRTSSRSR---SRSSSYDP-----H 1396
Query: 402 SRSRS----PNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRS--RSP 455
SRSRS +R RSRSRS ++ R RS N+ RS DRS S RSP
Sbjct: 1397 SRSRSYTYDSYYSRSRSRSRS-QRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSP 1455
Query: 456 NKARDHS 462
+++ +S
Sbjct: 1456 SESSRYS 1462
Score = 76.3 bits (186), Expect = 9e-14
Identities = 71/210 (33%), Positives = 107/210 (50%), Gaps = 28/210 (13%)
Query: 360 SKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419
SK + S + R + PR + S +P++ D S+SRSP+++R +S ++S
Sbjct: 1268 SKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRD-DDSQSRSPSRSRSKSETKSR 1326
Query: 420 YKARD------RSRSRSPN---KARDCSRSRSP-YKARDRSRSRSPNKARDHSRSRSPNK 469
++ R RSRSRS ++R SRSRS + +R R+RSRS + RS ++
Sbjct: 1327 HRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSS-----YRSYKSHR 1381
Query: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSK 529
RSRSRS S + HS+ S + + + RSRS S R RS S + R RS ++
Sbjct: 1382 TSSRSRSRSSSYD-PHSRSRSYTYDSYYSRSRSRS-----RSQRSDS----YHRGRSYNR 1431
Query: 530 ERQRRQSRSPNKERDRSQS--RSPSEEREH 557
+ +S + E DRS S RSPSE +
Sbjct: 1432 RSRSCRSYGSDSESDRSYSHHRSPSESSRY 1461
Score = 75.1 bits (183), Expect = 2e-13
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 26/196 (13%)
Query: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
+R P S ++P++ D S+SRSP SRSRS ++ + R+RS + + RSR
Sbjct: 1288 NRRPRNQESSSDEQTPSRDDD-SQSRSP------SRSRSKSETKSRHRTRSVSYSHSRSR 1340
Query: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ 535
SRS + S + R + RSRS + R SS R ++ R+ S+ R R
Sbjct: 1341 SRSST---------SSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSS 1391
Query: 536 SRSPNKERDRSQSRSPSEEREHRQSRSPSK-ERDRRRWRSPSKERERRQSRS----SSEE 590
S P+ S+SRS + + + +SRS S+ +R R S R R RS S +
Sbjct: 1392 SYDPH-----SRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESD 1446
Query: 591 RDHSRSRSPNKQSGYS 606
R +S RSP++ S YS
Sbjct: 1447 RSYSHHRSPSESSRYS 1462
Score = 67.4 bits (163), Expect = 4e-11
Identities = 61/188 (32%), Positives = 95/188 (50%), Gaps = 21/188 (11%)
Query: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557
R +R P + ++ S++ D +SRSPS+ R + +++S ++ R S S S S R
Sbjct: 1286 RLNRRPRNQESSSDEQTPSRD-DDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSS 1344
Query: 558 RQS-RSPSKERDRRR-WRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK 615
S RS S R R R W S R R +SRSSS RS ++ S SR R+SS +
Sbjct: 1345 TSSYRSRSYSRSRSRGWYS----RGRTRSRSSSY-----RSYKSHRTSSRSRSRSSSYDP 1395
Query: 616 AHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRT--------SSLSQNRT 667
HSRSR+ + + +S+SR+ S+ RS + + R+ S S +R+
Sbjct: 1396 -HSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRS 1454
Query: 668 PSKTSSHS 675
PS++S +S
Sbjct: 1455 PSESSRYS 1462
Score = 66.2 bits (160), Expect = 1e-10
Identities = 90/293 (30%), Positives = 136/293 (46%), Gaps = 45/293 (15%)
Query: 230 KSDNPSPSSSRKVKSYGQMIIPSR------EKSYSPTEMSSRVKSYNQASTRSRPQSHSQ 283
K D+ S S + +S G+ + + +K + P + + + N A+T S +
Sbjct: 1193 KQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPN-AATSSAVEVKVL 1251
Query: 284 SRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQN- 342
+ P G + ++S + R S + L++ R+ +S S + S++
Sbjct: 1252 TTVPEMKPQGLR----IEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDD 1307
Query: 343 --QSRTPRRGRSHNW--SRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQ 398
QSR+P R RS + SR+ ++ S+SHSRS S R S+S S RS+S S ++
Sbjct: 1308 DSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRS-----RSSTS----SYRSRSYSRSRS 1358
Query: 399 RD-HSRSRSPNKARDRSRSRSPYKA-RDRSRSRSPNKARD-CSRSRS----PYKARDRSR 451
R +SR R+ R RS S YK+ R SRSRS + + D SRSRS Y +R RSR
Sbjct: 1359 RGWYSRGRT----RSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSR 1414
Query: 452 SRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
SRS ++ + R RS N+ RS E D S H RS S S
Sbjct: 1415 SRS-QRSDSYHRGRSYNRRSRSCRSYGSDSESDRSY--------SHHRSPSES 1458
Score = 63.9 bits (154), Expect = 5e-10
Identities = 63/187 (33%), Positives = 94/187 (50%), Gaps = 20/187 (10%)
Query: 464 SRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRR 523
+R P S ++PS++ D SQ SPS+ R S+S +K R +S S S R R
Sbjct: 1288 NRRPRNQESSSDEQTPSRD-DDSQSRSPSRSR----SKSETKSRHRTRSVSYSHSRSRSR 1342
Query: 524 SRSPSKERQRRQSRSPNK---ERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERE 580
S S S R R SRS ++ R R++SRS S R ++ R+ S+ R R P
Sbjct: 1343 S-STSSYRSRSYSRSRSRGWYSRGRTRSRS-SSYRSYKSHRTSSRSRSRSSSYDP---HS 1397
Query: 581 RRQSRSSSEERDHSRSRSPNKQS-GYSRPRASSKEKAHSRSRTPSKEGNHSQS-RTSSKE 638
R +S + SRSRS +++S Y R R+ ++ RSR+ G+ S+S R+ S
Sbjct: 1398 RSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNR-----RSRSCRSYGSDSESDRSYSHH 1452
Query: 639 SDPSQST 645
PS+S+
Sbjct: 1453 RSPSESS 1459
Score = 58.9 bits (141), Expect = 2e-08
Identities = 99/387 (25%), Positives = 139/387 (35%), Gaps = 79/387 (20%)
Query: 360 SKERSHSHSRSSSK-ERDHRGS-------------SSPRKESGRSQSGSPNKQ----RDH 401
S S S S SSS+ E +H S S R++ S NK + H
Sbjct: 200 SSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGH 259
Query: 402 SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKA--- 458
S N+ R S K R P R + P+ A
Sbjct: 260 SERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIV 319
Query: 459 --RDHSRSRSPNKARDRS--------RSRSPSKERDHSQLGSPSKERDH----RRSRSPS 504
+ S S+S K + R RSRS S+ D +P ++ R R PS
Sbjct: 320 SDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPS 379
Query: 505 KERQCRQSRSS---SKERDHR----RSRSPS------------KERQRRQSRSPNKERDR 545
E+ + + S S D R RSRS S ++ R K + +
Sbjct: 380 GEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHK 439
Query: 546 SQSRSPSEEREHRQSR----------SPSKERDRRRWRSPSKERERRQSRSS---SEERD 592
+ + R H+Q++ SK RR S +ER R S S S +RD
Sbjct: 440 KKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRD 499
Query: 593 HSRSRSPNKQSGYSRPRASSKEKAH--------SRSRTPSKEGNHSQSRTSSKESDPSQS 644
S+S + S R S + K+H SRSRT SK +HS+SR+ S+ S S
Sbjct: 500 WSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGH 559
Query: 645 TVPRSPDWKRSPTRTSSLSQNRTPSKT 671
S +SP +T+S P KT
Sbjct: 560 RKRAS----KSPRKTASQLSENKPVKT 582
Score = 53.5 bits (127), Expect = 7e-07
Identities = 76/356 (21%), Positives = 126/356 (35%), Gaps = 37/356 (10%)
Query: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
K+ H S S S S + +H RSR R +K R + + RS
Sbjct: 190 KKPTHSEGSDSSSNSSSSSESSSESELEHERSR-----------RRKHKRRPKVK-RSKK 237
Query: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR--DRSRSRSPSKERDHSQLGS 490
+ ++ S S P R++ + HS N+ R D S R R
Sbjct: 238 RRKEASSSEEP-------RNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPV 290
Query: 491 PSKERDHRRSR---SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQ 547
P RR + E + ++ S+S K + R R R RS
Sbjct: 291 PENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSC 350
Query: 548 SRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSS------EERDHSRSRSPNK 601
S S ++ + + R +R PS E+ + + S +ER S+
Sbjct: 351 SESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWS 410
Query: 602 QSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST------VPRSPDWKRS 655
+GY ++++ H + R K+ H + K + T +P + +S
Sbjct: 411 YNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKS 470
Query: 656 PTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
TR S +R S SS S S+ S + S+ D ++ + ++ RS S S
Sbjct: 471 STRRMKSSCDRERSSRSS-SLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHS 525
Score = 50.1 bits (118), Expect = 7e-06
Identities = 158/749 (21%), Positives = 266/749 (35%), Gaps = 108/749 (14%)
Query: 27 KPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTS--TKRAPSNRPSSRSRV 84
K S +ST S +RS + + SR+S S T+S S + + S PSSRS
Sbjct: 669 KNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHS 728
Query: 85 RSKARTPSRVSTDTRTSKASKASDVRCHQR-RGTHSRGRTPGRRGSRSSKRSPSRASTPG 143
R+K S+ S + + S R +R R + + ++ S SS+++ G
Sbjct: 729 RNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKG 788
Query: 144 RIRTHGARPGMASRVR--------------TPTSQQKGSRG----------KSYGRPRT- 178
R R+ R SR T ++Q+K +G K+ G ++
Sbjct: 789 RDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSK 848
Query: 179 SNRERSDSQPRNLSKK-SYRPPGGS--------GIGRSSELAVTPSTAKCQTPTGIPSKE 229
S RE S+ R L + S GS G SE K PS +
Sbjct: 849 SERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSD 908
Query: 230 KSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRR 289
K + + S S S + + KS + T + + + +S Q S S S
Sbjct: 909 KEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPD-----DNGAWKSSKQRTSTSDSEGS 963
Query: 290 SRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRR 349
+ R + H K N R ++ K L KGK + + P+R
Sbjct: 964 CSNSENNRGKPQKHKHGSKENLKREHTKKVKEKL-------------KGKKDKKHKAPKR 1010
Query: 350 GRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK 409
++ +W P E +E D + + KE S++ K +S +
Sbjct: 1011 KQAFHWQ--PPLE----FGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEE 1064
Query: 410 ARDR-------SRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHS 462
S + D S SP A + + + + PN D
Sbjct: 1065 DLSGKHDTVTVSSDLDQFTKDDSKLSISPT-ALNTEENVACLQNIQHVEESVPNGVEDVL 1123
Query: 463 RSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR 522
++ + RS SP+K + S LG+ R +P +Q ++ +H
Sbjct: 1124 QTDDNMEICTPDRS-SPAKVEETSPLGNA-------RLDTPDINIVLKQDMAT----EHP 1171
Query: 523 RSRSPSKERQRRQSR---SPNKERDRSQSRSPSEEREHRQSRSPSKERDR--RRWR---- 573
++ +E +S+ K+ S S + + E ++ + + + ++W+
Sbjct: 1172 QAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKWKPLQG 1231
Query: 574 --------SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE--KAHSRSRTP 623
+ + + ++ E R K RP + E K +R P
Sbjct: 1232 VGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRP 1291
Query: 624 SKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683
+ + S +T S++ D SQS RSP RS + T S ++RT S + SHS S S
Sbjct: 1292 RNQESSSDEQTPSRDDD-SQS---RSPSRSRSKSETKS--RHRTRSVSYSHSRSR--SRS 1343
Query: 684 QTLSQDDSQADATTSKATLPGERSSSSSS 712
T S + S+ R+ S SS
Sbjct: 1344 STSSYRSRSYSRSRSRGWYSRGRTRSRSS 1372
Score = 47.4 bits (111), Expect = 5e-05
Identities = 56/195 (28%), Positives = 80/195 (41%), Gaps = 26/195 (13%)
Query: 32 LKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTP 91
+KS P SL T+R + + S+ + R ++ S SR RSK+ T
Sbjct: 1266 IKSKNKVRPG-SLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETK 1324
Query: 92 SRVST------DTRTSKASKASDVRCH-----QRRGTHSRGRTPGRRGS-------RSSK 133
SR T +R+ S S R + RG +SRGRT R S R+S
Sbjct: 1325 SRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSS 1384
Query: 134 RSPSRAST---PGRIRTHGARPGMASRVRTPTSQQKGS---RGKSYGRPRTSNRERSDSQ 187
RS SR+S+ R R++ SR R+ + Q+ RG+SY R S R
Sbjct: 1385 RSRSRSSSYDPHSRSRSY-TYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDS 1443
Query: 188 PRNLSKKSYRPPGGS 202
+ S +R P S
Sbjct: 1444 ESDRSYSHHRSPSES 1458
Score = 39.3 bits (90), Expect = 0.013
Identities = 64/224 (28%), Positives = 91/224 (40%), Gaps = 59/224 (26%)
Query: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGR 122
++ +S+S ++ PS S+SR S++R+ S + RT S + HSR R
Sbjct: 1292 RNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYS-----------HSRSR 1340
Query: 123 TPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRE 182
+ R S SS RS S + + R G SR RT SR SY R S+R
Sbjct: 1341 S---RSSTSSYRSRSYSRSRSR--------GWYSRGRTR------SRSSSY-RSYKSHRT 1382
Query: 183 RSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKV 242
S S+ R+ SY P S ++ T S+ + S S S++
Sbjct: 1383 SSRSRSRS---SSYDP---------------HSRSRSYTYDSYYSRSR----SRSRSQRS 1420
Query: 243 KSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRS 286
SY R +SY+ S R SY S R SH +S S
Sbjct: 1421 DSY------HRGRSYNRRSRSCR--SYGSDSESDRSYSHHRSPS 1456
Score = 35.8 bits (81), Expect = 0.14
Identities = 59/245 (24%), Positives = 86/245 (35%), Gaps = 51/245 (20%)
Query: 493 KERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERD--RSQSRS 550
K+ H S SS E +H RSR +R+ R P +R R + S
Sbjct: 190 KKPTHSEGSDSSSNSSSSSESSSESELEHERSR------RRKHKRRPKVKRSKKRRKEAS 243
Query: 551 PSEEREHRQSRSP---SKERDRRRWRSPSKERERRQSRSSSEE------------RD--- 592
SEE ++ + +P S+ D RS +R + EE RD
Sbjct: 244 SSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLLRRDMPV 303
Query: 593 ---HSRSRSPNKQSGYSRPRAS-SKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPR 648
+ P+ S + S SK + R + +SR+ S+ D S P
Sbjct: 304 VTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSETP- 362
Query: 649 SPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSS 708
P WK R L R PS G+ S+ D +D +S+ ERS
Sbjct: 363 -PHWKEEMQR---LRAYRPPS-------------GEKWSKGDKLSDPCSSRW---DERSL 402
Query: 709 SSSSK 713
S S+
Sbjct: 403 SQRSR 407
Score = 35.4 bits (80), Expect = 0.19
Identities = 48/167 (28%), Positives = 74/167 (44%), Gaps = 35/167 (20%)
Query: 23 TADPKPPASLKSTKSATPNRSLVPTKPAT---SRNSVMSPSSSKSTKSTSTKRAPSNRPS 79
++D + P+ ++S +P+RS ++ + +R+ S S S+S STS+ R+ R
Sbjct: 1297 SSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRS---RSY 1353
Query: 80 SRSRVR---SKARTPSRVS---------TDTRTSKASKASDVRCHQRRGTH----SRGRT 123
SRSR R S+ RT SR S T +R+ S + D R T+ SR R+
Sbjct: 1354 SRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRS 1413
Query: 124 PGR--------RGSRSSKRSPS-----RASTPGRIRTHGARPGMASR 157
R RG ++RS S S R +H P +SR
Sbjct: 1414 RSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSR 1460
Score = 32.7 bits (73), Expect = 1.2
Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Query: 529 KERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSS 588
++++++ + S + + S S E S+ R +R + ++RR+ SSS
Sbjct: 186 EKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSS 245
Query: 589 EERDHSRSRSPNKQSGYSRPRASSKEK 615
EE + + +P S R+ + EK
Sbjct: 246 EEPRNKHAMNPKGHS----ERSDTNEK 268
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 116 bits (291), Expect = 6e-26
Identities = 135/459 (29%), Positives = 206/459 (44%), Gaps = 87/459 (18%)
Query: 177 RTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSP 236
R S R+R + + + L + PP S A+ +PT P K +PS
Sbjct: 265 RRSRRQRREFREKRLRGRKISPP---------------SYARRDSPTYDPYKR---SPSE 306
Query: 237 SSSRKVKSYGQMIIPSREK------SYSPTEMSSRVKSYNQAS---TRSRPQSHSQSRSP 287
SSS +S + P RE+ S+ ++ + + A+ T +P + Q P
Sbjct: 307 SSSES-RSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGP 365
Query: 288 RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTP 347
R+ S +R S S S S +RS +R S SRS +G +S
Sbjct: 366 APGRNASARRRSSSSSSSSSASRTSSSRSSSR----------SSSRSR-RGGGYYRSGRH 414
Query: 348 RRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSP 407
R RS +WSR S+ RS +SRS S+ R H G S G S SP ++ + R
Sbjct: 415 ARSRSRSWSR--SRSRSRRYSRSRSRGRRHSGGGS---RDGHRYSRSPARRGGYGPRR-- 467
Query: 408 NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP 467
R RSRS S + R R + + SRSRS + SRSRS ++R HS S S
Sbjct: 468 ---RSRSRSHSGDRYRRGGRGLRHHSS---SRSRSSWSLSP-SRSRSLTRSRSHSPSPSQ 520
Query: 468 NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSR-SSSKERDHRRSR- 525
+++R RSRS+SPS SP++E+ R + SP+ + +++ ++ KE + +
Sbjct: 521 SRSRSRSRSQSPSP--------SPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKL 572
Query: 526 SPSKERQRRQSRSPNKE--RDRSQSRSPSEEREH-RQSRSPS----------KERDRRRW 572
+P ++ + R ++ N++ D+ ++ ++EH RQ R KER+RR
Sbjct: 573 TPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREK 632
Query: 573 RSPSKERE-RRQSRS----------SSEERDHSRSRSPN 600
ER+ RQSRS SS R SRSRSP+
Sbjct: 633 EREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPH 671
Score = 115 bits (289), Expect = 1e-25
Identities = 126/414 (30%), Positives = 191/414 (46%), Gaps = 52/414 (12%)
Query: 257 YSPTEMSSRVKSYNQASTRSR---PQSHSQSRSP-----RRSRSGSQKRTHSRVRSHSWK 308
YS + + + + R R P S+++ SP +RS S S + SR RS +
Sbjct: 262 YSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPG 321
Query: 309 RNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS-KERSHSH 367
R + T G + + + + + G + + P + RN S + RS S
Sbjct: 322 REE-KITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSS 380
Query: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSR 427
S SSS R SS R S + G + H+RSRS + +R RSRSR ++R R R
Sbjct: 381 SSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGR 440
Query: 428 SRSPNKARDCSR-SRSPYKA-------RDRSRSRSPNKARDHSRS-RSPNKARDRSR-SR 477
S +RD R SRSP + R RSRS S ++ R R R + +R RS S
Sbjct: 441 RHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSL 500
Query: 478 SPSKE----RDHSQLGSPSKERDHRRSR------SPSKERQCRQSRS------------- 514
SPS+ R S SPS+ R RSR SP++E+ R + S
Sbjct: 501 SPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPA 560
Query: 515 SSKERDHRRSR-SPSKERQRRQSRSPNKE--RDRSQSRSPSEEREH-RQSRSPSKERDRR 570
+ KE + + +P ++ + R ++ N++ D+ ++ ++EH RQ R R
Sbjct: 561 AGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMAR 620
Query: 571 RWRSPSKERERRQSRSSSEERDHSR-SRSPNKQSGYSRPRASSKEKAHSRSRTP 623
+ R KERERR+ ER +SR SRSP+ + YSR +SS+ ++ SRSR+P
Sbjct: 621 KIR--MKERERREKEREEWERQYSRQSRSPSPR--YSREYSSSRRRSRSRSRSP 670
Score = 102 bits (254), Expect = 1e-21
Identities = 117/411 (28%), Positives = 172/411 (41%), Gaps = 57/411 (13%)
Query: 133 KRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLS 192
KRSPS +S+ R R+ PG ++ T S G S + + S
Sbjct: 301 KRSPSESSSESRSRSRSPTPGREEKITFIT-----SFGGSDEEAAAAAAAAAASGVTTGK 355
Query: 193 KKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPS 252
+ PGG GR++ S++ + S +S + S S SR+ Y + +
Sbjct: 356 PPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHA 415
Query: 253 REKSYSPTEMSSRVKSYNQASTRSRPQS-------HSQSRSPRRSRSGSQKRTHSRVRSH 305
R +S S + SR + Y+++ +R R S H SRSP R R G R SR RSH
Sbjct: 416 RSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR-RGGYGPRRRSRSRSH 474
Query: 306 SWKRNHSRARSRTRKGILSQMGRHSQSRSHSK-GKSQNQSRTPRRGRSHNWSRNPSKERS 364
S R R + HS SRS S S ++SR+ R RSH S +PS+ RS
Sbjct: 475 SGDRYRRGGRG---------LRHHSSSRSRSSWSLSPSRSRSLTRSRSH--SPSPSQSRS 523
Query: 365 HSHSRSSSKERDHRGSSSPRKESGRSQSGSPN-----KQRDHSRSRSPNKARDRSRSRSP 419
S SRS S S SP +E + SP K+ + + + A+ + +
Sbjct: 524 RSRSRSQSP------SPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEK 577
Query: 420 YKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSP 479
K R + KA D+ ++ ++H R ++ R +R +
Sbjct: 578 LKLRMQKALNRQFKA-------------DKKAAQEKMIQQEHERQEREDELRAMAR-KIR 623
Query: 480 SKERDHSQLGSPSKERDH-RRSRSPSKERQCRQSR--SSSKERDHRRSRSP 527
KER+ + ER + R+SRSPS R SR SSS+ R RSRSP
Sbjct: 624 MKERERREKEREEWERQYSRQSRSPSP----RYSREYSSSRRRSRSRSRSP 670
Score = 99.8 bits (247), Expect = 8e-21
Identities = 118/452 (26%), Positives = 183/452 (40%), Gaps = 74/452 (16%)
Query: 153 GMASRVRTPTSQQKGSRGKSYGRPRTSNRE--------RSDSQPRNLSKKSYRPPGG--- 201
G SR + ++K RG+ P + R+ RS S+ + S+ R P
Sbjct: 264 GRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGRE 323
Query: 202 ------SGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREK 255
+ G S E A + A + G+ + + P P ++ S
Sbjct: 324 EKITFITSFGGSDEEAAAAAAAAAAS--GVTTGKPPAPPQPGGPAPGRNASARRRSSSSS 381
Query: 256 SYSPTEMSSRVKSYNQASTRSRPQS-------HSQSRSPRRSRSGSQKRTHSRVRSHSWK 308
S S +S +S +++S+RSR H++SRS SRS S+ R +SR RS
Sbjct: 382 SSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRG-- 439
Query: 309 RNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHS 368
R HS SR SR+P R R R S+ RSHS
Sbjct: 440 RRHSGGGSR---------------------DGHRYSRSPAR-RGGYGPRRRSRSRSHSGD 477
Query: 369 RSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRS 428
R R R SS R S S S S ++ SRS SP+ ++ RSRSRS RS+S
Sbjct: 478 RYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS------RSQS 531
Query: 429 RSPNKARD-CSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQ 487
SP+ AR+ +R + ++ + P ++ ++ +++ + R
Sbjct: 532 PSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRM--------- 582
Query: 488 LGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS---KERQRRQSRSPNKERD 544
+ R + + ++E+ +Q + D R+ + KER+RR+ ER
Sbjct: 583 --QKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQ 640
Query: 545 RS-QSRSPSEEREHRQSRSPSKERDRRRWRSP 575
S QSRSPS + + S S+ R R R RSP
Sbjct: 641 YSRQSRSPSP--RYSREYSSSRRRSRSRSRSP 670
Score = 92.8 bits (229), Expect = 1e-18
Identities = 95/327 (29%), Positives = 138/327 (42%), Gaps = 22/327 (6%)
Query: 401 HSRSRSPNKA-----RDRSRSRSPYKARDRSRSRSP-NKARDCSRSRSPYKARDRSRSRS 454
H+++ KA R R + R + R R R SP + AR S + PYK RS S
Sbjct: 251 HAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYK-----RSPS 305
Query: 455 PNKARDHSRSRSPNKARDRSRSRSPS---KERDHSQLGSPSKERDHRRSRSPSKERQCRQ 511
+ + SRSRSP R+ + S + + + + + + P+ +
Sbjct: 306 ESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGP 365
Query: 512 SRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPS---EEREHRQSRSPSKERD 568
+ + R S S S R S S + R S+SR H +SRS S R
Sbjct: 366 APGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRS 425
Query: 569 RRRWRSPSKERERRQSRSSSEERD-HSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEG 627
R R R S+ R R + S RD H SRSP ++ GY PR S+ ++HS R + G
Sbjct: 426 RSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYG-PRRRSRSRSHSGDR--YRRG 482
Query: 628 NHSQSRTSSKESDPSQSTVP-RSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTL 686
SS S S S P RS RS + + S SQ+R+ S++ S SPS P+ +
Sbjct: 483 GRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLT 542
Query: 687 SQDDSQADATTSKATLPGERSSSSSSK 713
S A K T P + ++K
Sbjct: 543 RPAASPAVGEKLKKTEPAAGKETGAAK 569
Score = 92.8 bits (229), Expect = 1e-18
Identities = 111/349 (31%), Positives = 155/349 (44%), Gaps = 49/349 (14%)
Query: 295 QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGR--------HSQSRSHSKGKSQNQSRT 346
+K +S RS +R R R RK R + +S S S +S+++SR+
Sbjct: 258 EKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRS 317
Query: 347 PRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRS 406
P GR + S S + +++ G ++ K Q G P R+ S
Sbjct: 318 PTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTG-KPPAPPQPGGPAPGRNAS---- 372
Query: 407 PNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRS 466
AR RS S S + R+ S S + +R SRSR R RS AR SRS S
Sbjct: 373 ---ARRRSSSSSSSSSASRTSS-SRSSSRSSSRSR-----RGGGYYRSGRHARSRSRSWS 423
Query: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERD-HRRSRSPSKERQCRQSRSSSKERDHRRSR 525
+++R R SRS S+ R HS GS RD HR SRSP++ R R RSR
Sbjct: 424 RSRSRSRRYSRSRSRGRRHSGGGS----RDGHRYSRSPAR-------RGGYGPRRRSRSR 472
Query: 526 SPSKERQRRQSRS---PNKERDRSQ-SRSPSEEREHRQSR----SPSKERDRRRWR---- 573
S S +R RR R + R RS S SPS R +SR SPS+ R R R R
Sbjct: 473 SHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSP 532
Query: 574 SPSKERERRQSRSSSE---ERDHSRSRSPNKQSGYSRPRASSKEKAHSR 619
SPS RE+ ++S E+ + K++G ++P+ + +EK R
Sbjct: 533 SPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLR 581
Score = 91.3 bits (225), Expect = 3e-18
Identities = 99/381 (25%), Positives = 152/381 (39%), Gaps = 31/381 (8%)
Query: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS 62
+P R K + + GS A A+ + P P PA RN+ SS
Sbjct: 319 TPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSS 378
Query: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGR 122
S+ S+S R S+R SSRS S++R R +++ S R R +SR R
Sbjct: 379 SSSSSSSASRTSSSRSSSRS--SSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
Query: 123 TPGRRGSRSSKRSPSRAS-TPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
+ GRR S R R S +P R +G R SR + ++G RG
Sbjct: 437 SRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL---------- 486
Query: 182 ERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
R S R+ S S P + RS + +PS ++ + S+ +S +PSPS +R+
Sbjct: 487 -RHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSR------SRSRSQSPSPSPARE 539
Query: 242 VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPR---RSRSGSQKRT 298
K P+ + TE ++ K A + PQ + R + R +K
Sbjct: 540 -KLTRPAASPAVGEKLKKTEPAAG-KETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAA 597
Query: 299 HSRV--RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWS 356
++ + H + R+ RK + + R + R + + QSR+P S +S
Sbjct: 598 QEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSP----SPRYS 653
Query: 357 RNPSKERSHSHSRSSSKERDH 377
R S R S SRS S H
Sbjct: 654 REYSSSRRRSRSRSRSPHYRH 674
Score = 82.4 bits (202), Expect = 1e-15
Identities = 118/432 (27%), Positives = 174/432 (40%), Gaps = 85/432 (19%)
Query: 71 KRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSR 130
KR+PS SS SR RS++ TP R T + + + + G T G+
Sbjct: 301 KRSPSES-SSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGK---- 355
Query: 131 SSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN 190
P PG G PG + R +S S S RTS+ R+
Sbjct: 356 -----PPAPPQPG-----GPAPGRNASARRRSSSSSSSSSAS----RTSS-------SRS 394
Query: 191 LSKKSYRPPGGSGIGRSSELAVTP----STAKCQTPTGIPSKEKSDNPSPSSSRKVKSYG 246
S+ S R G G RS A + S ++ ++ S+ + S SR Y
Sbjct: 395 SSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYS 454
Query: 247 QMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHS 306
+ P+R Y P S R +SHS R RR G + + SR RS S
Sbjct: 455 RS--PARRGGYGPRRRS-------------RSRSHSGDRY-RRGGRGLRHHSSSRSRS-S 497
Query: 307 WKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS-KERSH 365
W + SR+RS TR S SQSRS S+ +SQ+ S +P R + + +P+ E+
Sbjct: 498 WSLSPSRSRSLTRS--RSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLK 555
Query: 366 SHSRSSSKERDHRGSSSP----------RKESGRSQSGSPNK--------QRDHSRSRSP 407
++ KE G++ P R + ++ +K Q++H R
Sbjct: 556 KTEPAAGKE---TGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERE 612
Query: 408 NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP 467
++ R +R K R + R R + + R S +SRS SP +R++S SR
Sbjct: 613 DELRAMAR-----KIRMKERERREKEREEWERQYS-----RQSRSPSPRYSREYSSSR-- 660
Query: 468 NKARDRSRSRSP 479
R RSRSRSP
Sbjct: 661 --RRSRSRSRSP 670
Score = 78.6 bits (192), Expect = 2e-14
Identities = 83/290 (28%), Positives = 114/290 (39%), Gaps = 34/290 (11%)
Query: 370 SSSKERDHRGSSSPRKESGRSQSGSPNKQRD------HSRSRSPNKARDRSRSRSPYKAR 423
S + R R ++ GR S +RD + RS S + + RSRSRSP R
Sbjct: 263 SGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGR 322
Query: 424 DR------SRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSR 477
+ S S +A + + + P + + R S S
Sbjct: 323 EEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSS 382
Query: 478 SPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR 537
S S R S S RR + + +SRS S R RSR S+ R R +
Sbjct: 383 SSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRH 442
Query: 538 SPNKERDRSQSRSPSEEREHRQSRSPSKE-----RDRRRWRSPSKERERRQSRSSSEERD 592
S RD HR SRSP++ R R R RS S +R RR R R
Sbjct: 443 SGGGSRD-----------GHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL---RH 488
Query: 593 HSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPS 642
HS SRS +S +S + S+ SRS +PS + S+SR+ S+ PS
Sbjct: 489 HSSSRS---RSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPS 535
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 110 bits (275), Expect = 5e-24
Identities = 88/268 (32%), Positives = 132/268 (49%), Gaps = 12/268 (4%)
Query: 272 ASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQ 331
AS R + SP R + Q R+ + SR+RSR RK GR +
Sbjct: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
Query: 332 SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSR---SSSKERDHRGSSSPRKES- 387
SRS SK +++S+ + + H + KE S R +SS+ + R RK S
Sbjct: 63 SRSRSKEGRRHESKD-KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
Query: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
GRS S S +++R H RSRS + + RSRSR K+R RSR R +++R R R + R
Sbjct: 122 GRSHSRSRSRERRH-RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR---RIR 177
Query: 448 DRSRSRSPNKARDHSRSRSPNKARDR-SRSRSPSK-ERDHSQLGSPSKERDHRRSRSPSK 505
RSRSRS ++ R SRSR+ +++RDR R P + R S+ SP R R + ++
Sbjct: 178 SRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRG-RNTAMDAQ 236
Query: 506 ERQCRQSRSSSKERDHRRSRSPSKERQR 533
E R+ + K ++ R K++Q+
Sbjct: 237 EALARRLERAKKLQEQREKEMVEKQKQQ 264
Score = 107 bits (268), Expect = 3e-23
Identities = 87/264 (32%), Positives = 130/264 (49%), Gaps = 17/264 (6%)
Query: 370 SSSKERDHRG--SSSPRKESGRSQSG---SPNKQRDH-SRSRSPNKARDRSRSRSPYKAR 423
+S ERD +SP ++ + QS SP + H SRSRS ++ R R K R
Sbjct: 3 ASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR 62
Query: 424 DRSRSRSPNKARDCSRSRSPYKARDRS-RSRSPNKARDHSRSRSPNKARDRSRSRSPSKE 482
RSRS+ + +S +K+ + + + S +K R+ S + R + + R S+
Sbjct: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
Query: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
R HS+ S S+ER HR S+ R+ ++SRS S+ER ++SRS S+ER++ +SRS ++
Sbjct: 123 RSHSR--SRSRERRHR-----SRSRERKKSRSRSRER--KKSRSRSRERKKSRSRSRERK 173
Query: 543 RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQ 602
R R +SRS S R ++RS S+ R R R R E+ RR SRS S R N
Sbjct: 174 R-RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTA 232
Query: 603 SGYSRPRASSKEKAHSRSRTPSKE 626
A E+A KE
Sbjct: 233 MDAQEALARRLERAKKLQEQREKE 256
Score = 103 bits (258), Expect = 4e-22
Identities = 80/259 (30%), Positives = 125/259 (48%), Gaps = 17/259 (6%)
Query: 332 SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRG---SSSPRKESG 388
S K K Q++ R H++SR+ S+ R +S ++ R HR S R+
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKR-KSDNEGRKHRSRSRSKEGRRHES 75
Query: 389 RSQSGSPNKQRDHS-RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
+ +S +K +H+ + S +K R+R S + R + + R ++ R SRSRS + R
Sbjct: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-R 134
Query: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR-RSRSPSKE 506
RSRSR K+R SRSR K+R RSR R S+ R S+ER R RSRS S+
Sbjct: 135 HRSRSRERKKSR--SRSRERKKSRSRSRERKKSRSR--------SRERKRRIRSRSRSRS 184
Query: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKE 566
R ++RS S+ R R R E+ RR SRS ++ R + + +++ + E
Sbjct: 185 RHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLE 244
Query: 567 RDRRRWRSPSKERERRQSR 585
R ++ KE +Q +
Sbjct: 245 RAKKLQEQREKEMVEKQKQ 263
Score = 94.0 bits (232), Expect = 4e-19
Identities = 73/228 (32%), Positives = 109/228 (47%), Gaps = 14/228 (6%)
Query: 474 SRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER------QCRQSRSSSKERDHRRSRSP 527
S R KE+ + + + + RSRS S+ER + R+ RS S+ ++ RR S
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
Query: 528 SKERQRRQSRSPN-KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERER-RQSR 585
K ++ +S N KE + R E+ + R KER R RS S+ R R R+ R
Sbjct: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 136
Query: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
S S ER SRSRS ++ SR R K ++ SR R K S+SR+ S+ ++S
Sbjct: 137 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER---KRRIRSRSRSRSRHRHRTRS- 192
Query: 646 VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693
RS RS R + + R S++ S +PS P G+ + D +A
Sbjct: 193 --RSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEA 238
Score = 75.9 bits (185), Expect = 1e-13
Identities = 77/287 (26%), Positives = 123/287 (42%), Gaps = 41/287 (14%)
Query: 151 RPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSEL 210
R G+A +P +K + + PR S S S+ R+ +K R S+
Sbjct: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERK-----------RKSDN 56
Query: 211 AVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYN 270
++ ++ G + K SS+K KS +K +S + R+ S
Sbjct: 57 EGRKHRSRSRSKEGRRHESKD-----KSSKKHKSE-----EHNDKEHSSDKGRERLNSSE 106
Query: 271 QASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHS 330
R + + SR SRS S++R H RS S +R SR+RSR RK S
Sbjct: 107 NGEDRHKRKERKSSRGRSHSRSRSRERRH---RSRSRERKKSRSRSRERK--------KS 155
Query: 331 QSRSHSKGKSQNQSR-TPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGR 389
+SRS + KS+++SR RR RS + SR+ + R+ S SR+ S+ RD + + R
Sbjct: 156 RSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 215
Query: 390 SQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436
S S +P S P + R+ + AR R++ + R+
Sbjct: 216 SLSRTP--------SPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 254
Score = 60.5 bits (145), Expect = 5e-09
Identities = 64/253 (25%), Positives = 106/253 (41%), Gaps = 24/253 (9%)
Query: 130 RSSKRSPSRAS-TPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQP 188
R K+ S S +P + H +R SR R S +G + +S R + R S
Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHES---- 75
Query: 189 RNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQM 248
++ S K ++ + SS+ G S+N RK + +
Sbjct: 76 KDKSSKKHKSEEHNDKEHSSD-------------KGRERLNSSENGEDRHKRKERKSSRG 122
Query: 249 IIPSREKSYSPTEMS-SRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSW 307
SR +S S SR + +++ +R R +S S+SR ++SRS S++R R+RS S
Sbjct: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR-RIRSRSR 181
Query: 308 KRNHSRA----RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER 363
R+ R RSRTR + R + R S+ S+ S P RGR+ + R
Sbjct: 182 SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALAR 241
Query: 364 SHSHSRSSSKERD 376
++ ++R+
Sbjct: 242 RLERAKKLQEQRE 254
Score = 47.0 bits (110), Expect = 6e-05
Identities = 44/200 (22%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 5 KRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRS-LVPTKPATSRNSVMSPSSSK 63
K+ + +S++P S + + + + KS R ++ R SSK
Sbjct: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSK 81
Query: 64 STKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRT 123
KS + R R+ S R R S ++ + R SR R
Sbjct: 82 KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE 141
Query: 124 PGRRGSRSSKRSPSRAST----PGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTS 179
+ SRS +R SR+ + R R+ + + SR R+ + + +R +S R R+
Sbjct: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
Query: 180 NRERSDSQPRNLSKKSYRPP 199
+R++ +PR S+ R P
Sbjct: 202 DRKKRIEKPRRFSRSLSRTP 221
Score = 43.1 bits (100), Expect = 9e-04
Identities = 41/150 (27%), Positives = 59/150 (39%), Gaps = 15/150 (10%)
Query: 32 LKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPS---NRPSSRSRVRSKA 88
L S+++ K + R+ S S + +S S +R S +R +SR RS+
Sbjct: 102 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
Query: 89 RTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGR------------RGSRSSKRSP 136
R SR + R + S R R T SR RT R R SRS R+P
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 221
Query: 137 SRASTPGRIRTHGARPGMASRVRTPTSQQK 166
S GR A+ +A R+ Q+
Sbjct: 222 SPPPFRGRNTAMDAQEALARRLERAKKLQE 251
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 108 bits (271), Expect = 1e-23
Identities = 71/265 (26%), Positives = 121/265 (45%), Gaps = 7/265 (2%)
Query: 368 SRSSSKERD-HRG--SSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARD 424
SR SK RD H+ +KE R + ++R+ R R + R+R R R + R+
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER-RERERERERERERE 336
Query: 425 RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERD 484
+ + R + RD R R+ + RDR R R ++ R+ S R+ +++R R +SR +ER+
Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Query: 485 HSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERD 544
+ +ER+ R R +ER+ + R K+RD + ER++ + + KE
Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456
Query: 545 RSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604
+ E RE +++R KE +R R +E ++ + E+ D R +
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGS 516
Query: 605 YSRPRASSKEK---AHSRSRTPSKE 626
+ R +EK A R R KE
Sbjct: 517 ALQKRLRDREKEMEADERDRKREKE 541
Score = 104 bits (260), Expect = 2e-22
Identities = 83/378 (21%), Positives = 147/378 (38%), Gaps = 45/378 (11%)
Query: 332 SRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQ 391
SR SK + ++ +G+ + KER R +ER+ R R+
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERERERERRERERERERE---- 332
Query: 392 SGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR 451
++R+ + R + RDR R R+ + RDR R R ++ R+ S R+ ++R R +
Sbjct: 333 -----REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREK 387
Query: 452 SRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQ 511
SR + R+ R R + R+R R R +ER+ + K+RD + ER+ +
Sbjct: 388 SRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLE 447
Query: 512 SRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERD--- 568
+ KE ++ + R+R+++R KE +R + R +E ++ + ++ D
Sbjct: 448 RKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDR 507
Query: 569 -------------RRRWRSPSKERERRQSRSSSEERDHSRSR-------SPNKQSGYSRP 608
R R R E + R + EE + R R P+ +
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQ 567
Query: 609 RASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWK----------RSPTR 658
A + + + S+E + K +P + P+ K S
Sbjct: 568 EAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEE--EEEPEQKPCLKPTLRPISSAPS 625
Query: 659 TSSLSQNRTPSKTSSHSP 676
SS S N TP+ SP
Sbjct: 626 VSSASGNATPNTPGDESP 643
Score = 94.4 bits (233), Expect = 3e-19
Identities = 92/431 (21%), Positives = 159/431 (36%), Gaps = 39/431 (9%)
Query: 296 KRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNW 355
K+ R +R R R R R+ R + R + + + + + R R +
Sbjct: 297 KKEKERQEIEKERRERERERERERE-------RREREREREREREREKEKERERERERDR 349
Query: 356 SRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSR 415
R+ +KER R ++RD SS K+ RS+ S +++R+ R R + R+R R
Sbjct: 350 DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 409
Query: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR-------------SRSPN-KARDH 461
R + R+R R R K + R A +R + R N + R+
Sbjct: 410 EREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRER 469
Query: 462 SRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERD-------HRRSRSPSKERQCRQSRS 514
++R K +R R ++ +L ++ D + R + K + R+
Sbjct: 470 KKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEM 529
Query: 515 SSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR-SPSKERDRRRWR 573
+ ERD +R + +E ++R + + D R E RQ + E +
Sbjct: 530 EADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589
Query: 574 SPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQ-S 632
KE +R + EE + P + S P SS S + TP+ G+ S
Sbjct: 590 KQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSA----SGNATPNTPGDESPCG 645
Query: 633 RTSSKESDPSQSTVPRSPDWKRSPTRTS-SLSQNRTPSKTSSHSPSTFPSGGQTLSQDDS 691
E+ P Q + P+ R S L + +P + +S P +D
Sbjct: 646 IIIPHENSPDQ----QQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDE 701
Query: 692 QADATTSKATL 702
+D K L
Sbjct: 702 DSDDVPRKRKL 712
Score = 73.2 bits (178), Expect = 8e-13
Identities = 68/336 (20%), Positives = 118/336 (35%), Gaps = 32/336 (9%)
Query: 265 RVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILS 324
R + + R R + + R+ R R ++R R R S RN R+RSR +
Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREK----- 387
Query: 325 QMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR 384
SR + + + + R R R R +ER R K+RD
Sbjct: 388 -------SRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440
Query: 385 KESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPY 444
E + + K+ + + R+R ++R K +R R A++ R +
Sbjct: 441 YERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFL 500
Query: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
+ D RD + + + R R R E D ERD +R +
Sbjct: 501 EDYDDD--------RDDPKYYRGSALQKRLRDREKEMEAD---------ERDRKREKEEL 543
Query: 505 KERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPS 564
+E + R + D R + +RRQ P +++ E++E + R
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQ---PQIKQEPESEEEEEEKQEKEEKREEP 600
Query: 565 KERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN 600
E + + P + R S+ S + +PN
Sbjct: 601 MEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPN 636
Score = 55.8 bits (133), Expect = 1e-07
Identities = 43/175 (24%), Positives = 73/175 (41%), Gaps = 22/175 (12%)
Query: 486 SQLGSPSKERD-HRRSRSPSKERQC-----------------RQSRSSSKERDHRR--SR 525
S+L +PS+E D H R + K+ + E D R SR
Sbjct: 220 SELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISR 279
Query: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSR 585
SK R + K + + + +ER R+ R +ER+RR R +ERER + +
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERE-RERERERERRE-REREREREREREK 337
Query: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD 640
ER+ R R ++ R R +++ R R+ + + S+SR S++ +
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRE 392
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 108 bits (270), Expect = 2e-23
Identities = 123/460 (26%), Positives = 199/460 (43%), Gaps = 71/460 (15%)
Query: 221 TPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTE-MSSRVKSYNQASTRSRPQ 279
T +P KE + S K S G+ +P K P S+ ++ N+A RP
Sbjct: 1679 TEEPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADL-VRPL 1737
Query: 280 SHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGK 339
R+G + + R RS + S R S+S S K
Sbjct: 1738 LPKDMERLTSLRAG--------IEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDD 1789
Query: 340 SQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQR 399
+ + + E+S + E++ + SS R S RS+S ++
Sbjct: 1790 YEIFVKV-----------KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRK 1838
Query: 400 DHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKAR 459
S SRS +AR RS ++++ RSRSRS + R +R RS+SR
Sbjct: 1839 RTSESRS--RARKRSSKSKSHRSQTRSRSRSRRRRRS---------SRSRSKSRGRRSVS 1887
Query: 460 DHSRSRSP-NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
R RSP ++++ R R R S RD+ + RRSRS + R+ R+SRS +
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR-RRSRSVGRR 1946
Query: 519 RDH-----RRSRSPSKERQ--RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRR 571
R RRSR+PS+ + R+SR+P++ +SR+PS R+SR+PS RR
Sbjct: 1947 RSFSISPSRRSRTPSRRSRTPSRRSRTPSR-----RSRTPS-----RRSRTPS-----RR 1991
Query: 572 WRSPSKERERRQSRSSSEERDHS-------RSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624
R+PS+ RR+SRS R S RSR+P ++ P + ++ R R+P
Sbjct: 1992 SRTPSR---RRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048
Query: 625 KEGNHSQSR-----TSSKESDPSQSTVPRSPDWKRSPTRT 659
+ + +++ ++ + +++ VP P+ K +P T
Sbjct: 2049 RLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT 2088
Score = 90.5 bits (223), Expect = 5e-18
Identities = 92/275 (33%), Positives = 134/275 (48%), Gaps = 43/275 (15%)
Query: 413 RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPN-----KARDHSRSRSP 467
R+ P A D R RS A S P +A + S + K +D
Sbjct: 1749 RAGIEGPLLASDVGRDRS---AASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKK 1805
Query: 468 NKARDRSRSRSPSKERDHS--QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR--- 522
NK RD+ K+RD S SK +H+ SR + E + R + SSK + HR
Sbjct: 1806 NKNRDKGEKE---KKRDSSLRSRSKRSKSSEHK-SRKRTSESRSRARKRSSKSKSHRSQT 1861
Query: 523 RSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR 582
RSRS S+ R+RR SRS +K R R RS S+E+ R + SK R+R+R RS S++ +
Sbjct: 1862 RSRSRSR-RRRRSSRSRSKSRGR---RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT 1917
Query: 583 QSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHS-----RSRTPSKEGNHSQSRTSSK 637
S SRS +P+++ R R+ + ++ S RSRTPS+ +SRT S+
Sbjct: 1918 VRARSRTPSRRSRSHTPSRR---RRSRSVGRRRSFSISPSRRSRTPSR-----RSRTPSR 1969
Query: 638 ES-DPSQSTVPRSPDWK-RSPTRTSSLSQNRTPSK 670
S PS+ + R+P + R+P+R S RTPS+
Sbjct: 1970 RSRTPSRRS--RTPSRRSRTPSRRS-----RTPSR 1997
Score = 84.3 bits (207), Expect = 3e-16
Identities = 74/240 (30%), Positives = 111/240 (46%), Gaps = 19/240 (7%)
Query: 443 PYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE-----RDHSQLGSPSKERDH 497
P A D R RS A S P +A + S E +D + +K RD
Sbjct: 1755 PLLASDVGRDRS---AASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRD- 1810
Query: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557
+ + ++ R SK +H+ + S+ R R + RS + RSQ+RS S R
Sbjct: 1811 KGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR 1870
Query: 558 RQ-SRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKA 616
R+ SRS SK R R RS SKE+ +R + S+ R+ R RS ++ + + S
Sbjct: 1871 RRSSRSRSKSRGR---RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 617 HSRSRTPS-KEGNHSQSRTSSKESDPSQSTVPRSPDWK-RSPTRTSSL--SQNRTPSKTS 672
SRS TPS + + S R S PS+ + R+P + R+P+R S ++RTPS+ S
Sbjct: 1928 RSRSHTPSRRRRSRSVGRRRSFSISPSRRS--RTPSRRSRTPSRRSRTPSRRSRTPSRRS 1985
Score = 77.0 bits (188), Expect = 6e-14
Identities = 71/246 (28%), Positives = 116/246 (47%), Gaps = 16/246 (6%)
Query: 459 RDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
RD S + + S S S+E+D ++ K+ + ++ ++++ ++ + S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 519 RDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE 578
R R RS S E + R+ S ++ R R +S R +SRS S+ R RR RS SK
Sbjct: 1823 RS-RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR-RRSSRSRSKS 1880
Query: 579 RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK---AHSRSRTPSKEG-NHSQSRT 634
R R RS S+E+ + +K R R+SS++ +RSRTPS+ +H+ SR
Sbjct: 1881 RGR---RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR 1937
Query: 635 SSKESDPSQSTVPRSPDWK-RSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693
S + + SP + R+P+R S RTPS+ S +PS S+ S+
Sbjct: 1938 RRSRSVGRRRSFSISPSRRSRTPSRRS-----RTPSR-RSRTPSRRSRTPSRRSRTPSRR 1991
Query: 694 DATTSK 699
T S+
Sbjct: 1992 SRTPSR 1997
Score = 67.4 bits (163), Expect = 4e-11
Identities = 64/216 (29%), Positives = 100/216 (46%), Gaps = 15/216 (6%)
Query: 510 RQSRSSSKERDH-------RRSRSPSKERQRRQSRSPNKERDRS-QSRSP-SEEREHRQS 560
R S SSS+E+D + + SK+ + R K+RD S +SRS S+ EH+
Sbjct: 1778 RASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSR 1837
Query: 561 RSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS 620
+ S+ R R R RS + R Q+RS S R R RS +S R+ SKEK
Sbjct: 1838 KRTSESRSRARKRSSKSKSHRSQTRSRSRSR--RRRRSSRSRSKSRGRRSVSKEKRKRSP 1895
Query: 621 RTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSS---LSQNRTPSKTSSHSPS 677
+ SK + R+SS+++ + R+P +RS + T S S++ ++ S SPS
Sbjct: 1896 KHRSKSRERKRKRSSSRDNRKTVRARSRTPS-RRSRSHTPSRRRRSRSVGRRRSFSISPS 1954
Query: 678 TFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
S+ S+ T S+ + R S + S+
Sbjct: 1955 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990
Score = 58.9 bits (141), Expect = 2e-08
Identities = 80/313 (25%), Positives = 127/313 (40%), Gaps = 47/313 (15%)
Query: 33 KSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPS 92
+ +A+P S +P + + S S K K ++ S +++ R K
Sbjct: 1763 RDRSAASPVVSSMPERASESS------SEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK 1816
Query: 93 RVSTDTRT-SKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGAR 151
+ + R+ SK SK+S+ + ++R + SR R R S RS +R+ + R R +R
Sbjct: 1817 KRDSSLRSRSKRSKSSEHKS-RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR 1875
Query: 152 PGMASRVRTPTSQQKGSRG-KSYGRPRTSNRERSDSQP--------------RNLSKKSY 196
SR R S++K R K + R R+RS S+ R+ S
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935
Query: 197 RPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKS 256
R +GR +++PS + +TP+ +S PS S PSR +S
Sbjct: 1936 RRRRSRSVGRRRSFSISPS-RRSRTPS-----RRSRTPSRRSR----------TPSR-RS 1978
Query: 257 YSPTEMSSRVKSYNQASTRSR-PQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRAR 315
+P+ S S RSR P +SRS R RS S R +R SR+
Sbjct: 1979 RTPSRRS------RTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSP 2032
Query: 316 SRTRKGILSQMGR 328
R ++ S+ GR
Sbjct: 2033 IRRKRSRSSERGR 2045
Score = 52.8 bits (125), Expect = 1e-06
Identities = 75/274 (27%), Positives = 114/274 (41%), Gaps = 48/274 (17%)
Query: 25 DPKPPASLKSTKS---ATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSR 81
+ K +SL+S ++ ++S T + SR S S SKS +S + R+ S R
Sbjct: 1815 EKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-SKSKSHRSQTRSRSRSRRRRRS 1873
Query: 82 SRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRAS- 140
SR RSK+R VS + R S R +R+ + SR R+ R+ R+PSR S
Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN---RKTVRARSRTPSRRSR 1930
Query: 141 --TPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRP 198
TP R R R +S GR R+ + S + R S++S P
Sbjct: 1931 SHTPSRRR----------------------RSRSVGRRRSFSISPS-RRSRTPSRRSRTP 1967
Query: 199 PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYS 258
S + TPS + +TP+ + +PS R+ +S ++ R S S
Sbjct: 1968 ---------SRRSRTPS-RRSRTPSRRSRTPSRRSRTPSRRRRSRS----VVRRRSFSIS 2013
Query: 259 PTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
P + + +RS P +SRS R RS
Sbjct: 2014 PVRLRRSRTPLRRRFSRS-PIRRKRSRSSERGRS 2046
Score = 31.2 bits (69), Expect = 3.5
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 7 SSKPSMSLAPSGSSMPTADPKPPASLKST--KSAT--PNRSLVPTKPATSRNSVMSPSSS 62
+S PS+ ++ + ++P P+P +S+ T +SA +VP +P T S S+
Sbjct: 1234 ASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSA 1293
Query: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVST 96
+ T S S + +R+ S VST
Sbjct: 1294 EPTVLASEPPVMSETAETFDSMRASGHVASEVST 1327
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 108 bits (270), Expect = 2e-23
Identities = 123/460 (26%), Positives = 199/460 (43%), Gaps = 71/460 (15%)
Query: 221 TPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTE-MSSRVKSYNQASTRSRPQ 279
T +P KE + S K S G+ +P K P S+ ++ N+A RP
Sbjct: 1679 TEEPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADL-VRPL 1737
Query: 280 SHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGK 339
R+G + + R RS + S R S+S S K
Sbjct: 1738 LPKDMERLTSLRAG--------IEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDD 1789
Query: 340 SQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQR 399
+ + + E+S + E++ + SS R S RS+S ++
Sbjct: 1790 YEIFVKV-----------KDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRK 1838
Query: 400 DHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKAR 459
S SRS +AR RS ++++ RSRSRS + R +R RS+SR
Sbjct: 1839 RTSESRS--RARKRSSKSKSHRSQTRSRSRSRRRRRS---------SRSRSKSRGRRSVS 1887
Query: 460 DHSRSRSP-NKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
R RSP ++++ R R R S RD+ + RRSRS + R+ R+SRS +
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR-RRSRSVGRR 1946
Query: 519 RDH-----RRSRSPSKERQ--RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRR 571
R RRSR+PS+ + R+SR+P++ +SR+PS R+SR+PS RR
Sbjct: 1947 RSFSISPSRRSRTPSRRSRTPSRRSRTPSR-----RSRTPS-----RRSRTPS-----RR 1991
Query: 572 WRSPSKERERRQSRSSSEERDHS-------RSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624
R+PS+ RR+SRS R S RSR+P ++ P + ++ R R+P
Sbjct: 1992 SRTPSR---RRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048
Query: 625 KEGNHSQSR-----TSSKESDPSQSTVPRSPDWKRSPTRT 659
+ + +++ ++ + +++ VP P+ K +P T
Sbjct: 2049 RLTDLDKAQLLEIAKANAAAMCAKAGVPLPPNLKPAPPPT 2088
Score = 90.5 bits (223), Expect = 5e-18
Identities = 92/275 (33%), Positives = 134/275 (48%), Gaps = 43/275 (15%)
Query: 413 RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPN-----KARDHSRSRSP 467
R+ P A D R RS A S P +A + S + K +D
Sbjct: 1749 RAGIEGPLLASDVGRDRS---AASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKK 1805
Query: 468 NKARDRSRSRSPSKERDHS--QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR--- 522
NK RD+ K+RD S SK +H+ SR + E + R + SSK + HR
Sbjct: 1806 NKNRDKGEKE---KKRDSSLRSRSKRSKSSEHK-SRKRTSESRSRARKRSSKSKSHRSQT 1861
Query: 523 RSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR 582
RSRS S+ R+RR SRS +K R R RS S+E+ R + SK R+R+R RS S++ +
Sbjct: 1862 RSRSRSR-RRRRSSRSRSKSRGR---RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT 1917
Query: 583 QSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHS-----RSRTPSKEGNHSQSRTSSK 637
S SRS +P+++ R R+ + ++ S RSRTPS+ +SRT S+
Sbjct: 1918 VRARSRTPSRRSRSHTPSRR---RRSRSVGRRRSFSISPSRRSRTPSR-----RSRTPSR 1969
Query: 638 ES-DPSQSTVPRSPDWK-RSPTRTSSLSQNRTPSK 670
S PS+ + R+P + R+P+R S RTPS+
Sbjct: 1970 RSRTPSRRS--RTPSRRSRTPSRRS-----RTPSR 1997
Score = 84.3 bits (207), Expect = 3e-16
Identities = 74/240 (30%), Positives = 111/240 (46%), Gaps = 19/240 (7%)
Query: 443 PYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE-----RDHSQLGSPSKERDH 497
P A D R RS A S P +A + S E +D + +K RD
Sbjct: 1755 PLLASDVGRDRS---AASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRD- 1810
Query: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557
+ + ++ R SK +H+ + S+ R R + RS + RSQ+RS S R
Sbjct: 1811 KGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR 1870
Query: 558 RQ-SRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKA 616
R+ SRS SK R R RS SKE+ +R + S+ R+ R RS ++ + + S
Sbjct: 1871 RRSSRSRSKSRGR---RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR 1927
Query: 617 HSRSRTPS-KEGNHSQSRTSSKESDPSQSTVPRSPDWK-RSPTRTSSL--SQNRTPSKTS 672
SRS TPS + + S R S PS+ + R+P + R+P+R S ++RTPS+ S
Sbjct: 1928 RSRSHTPSRRRRSRSVGRRRSFSISPSRRS--RTPSRRSRTPSRRSRTPSRRSRTPSRRS 1985
Score = 77.0 bits (188), Expect = 6e-14
Identities = 71/246 (28%), Positives = 116/246 (47%), Gaps = 16/246 (6%)
Query: 459 RDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
RD S + + S S S+E+D ++ K+ + ++ ++++ ++ + S
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822
Query: 519 RDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE 578
R R RS S E + R+ S ++ R R +S R +SRS S+ R RR RS SK
Sbjct: 1823 RS-RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRR-RRSSRSRSKS 1880
Query: 579 RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK---AHSRSRTPSKEG-NHSQSRT 634
R R RS S+E+ + +K R R+SS++ +RSRTPS+ +H+ SR
Sbjct: 1881 RGR---RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR 1937
Query: 635 SSKESDPSQSTVPRSPDWK-RSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693
S + + SP + R+P+R S RTPS+ S +PS S+ S+
Sbjct: 1938 RRSRSVGRRRSFSISPSRRSRTPSRRS-----RTPSR-RSRTPSRRSRTPSRRSRTPSRR 1991
Query: 694 DATTSK 699
T S+
Sbjct: 1992 SRTPSR 1997
Score = 67.4 bits (163), Expect = 4e-11
Identities = 64/216 (29%), Positives = 100/216 (46%), Gaps = 15/216 (6%)
Query: 510 RQSRSSSKERDH-------RRSRSPSKERQRRQSRSPNKERDRS-QSRSP-SEEREHRQS 560
R S SSS+E+D + + SK+ + R K+RD S +SRS S+ EH+
Sbjct: 1778 RASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSR 1837
Query: 561 RSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS 620
+ S+ R R R RS + R Q+RS S R R RS +S R+ SKEK
Sbjct: 1838 KRTSESRSRARKRSSKSKSHRSQTRSRSRSR--RRRRSSRSRSKSRGRRSVSKEKRKRSP 1895
Query: 621 RTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSS---LSQNRTPSKTSSHSPS 677
+ SK + R+SS+++ + R+P +RS + T S S++ ++ S SPS
Sbjct: 1896 KHRSKSRERKRKRSSSRDNRKTVRARSRTPS-RRSRSHTPSRRRRSRSVGRRRSFSISPS 1954
Query: 678 TFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
S+ S+ T S+ + R S + S+
Sbjct: 1955 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR 1990
Score = 58.9 bits (141), Expect = 2e-08
Identities = 80/313 (25%), Positives = 127/313 (40%), Gaps = 47/313 (15%)
Query: 33 KSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPS 92
+ +A+P S +P + + S S K K ++ S +++ R K
Sbjct: 1763 RDRSAASPVVSSMPERASESS------SEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK 1816
Query: 93 RVSTDTRT-SKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGAR 151
+ + R+ SK SK+S+ + ++R + SR R R S RS +R+ + R R +R
Sbjct: 1817 KRDSSLRSRSKRSKSSEHKS-RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSR 1875
Query: 152 PGMASRVRTPTSQQKGSRG-KSYGRPRTSNRERSDSQP--------------RNLSKKSY 196
SR R S++K R K + R R+RS S+ R+ S
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935
Query: 197 RPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKS 256
R +GR +++PS + +TP+ +S PS S PSR +S
Sbjct: 1936 RRRRSRSVGRRRSFSISPS-RRSRTPS-----RRSRTPSRRSR----------TPSR-RS 1978
Query: 257 YSPTEMSSRVKSYNQASTRSR-PQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRAR 315
+P+ S S RSR P +SRS R RS S R +R SR+
Sbjct: 1979 RTPSRRS------RTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSP 2032
Query: 316 SRTRKGILSQMGR 328
R ++ S+ GR
Sbjct: 2033 IRRKRSRSSERGR 2045
Score = 52.8 bits (125), Expect = 1e-06
Identities = 75/274 (27%), Positives = 114/274 (41%), Gaps = 48/274 (17%)
Query: 25 DPKPPASLKSTKS---ATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSR 81
+ K +SL+S ++ ++S T + SR S S SKS +S + R+ S R
Sbjct: 1815 EKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-SKSKSHRSQTRSRSRSRRRRRS 1873
Query: 82 SRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRAS- 140
SR RSK+R VS + R S R +R+ + SR R+ R+ R+PSR S
Sbjct: 1874 SRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN---RKTVRARSRTPSRRSR 1930
Query: 141 --TPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRP 198
TP R R R +S GR R+ + S + R S++S P
Sbjct: 1931 SHTPSRRR----------------------RSRSVGRRRSFSISPS-RRSRTPSRRSRTP 1967
Query: 199 PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYS 258
S + TPS + +TP+ + +PS R+ +S ++ R S S
Sbjct: 1968 ---------SRRSRTPS-RRSRTPSRRSRTPSRRSRTPSRRRRSRS----VVRRRSFSIS 2013
Query: 259 PTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
P + + +RS P +SRS R RS
Sbjct: 2014 PVRLRRSRTPLRRRFSRS-PIRRKRSRSSERGRS 2046
Score = 31.2 bits (69), Expect = 3.5
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 7 SSKPSMSLAPSGSSMPTADPKPPASLKST--KSAT--PNRSLVPTKPATSRNSVMSPSSS 62
+S PS+ ++ + ++P P+P +S+ T +SA +VP +P T S S+
Sbjct: 1234 ASDPSVLVSEAAVTVPEPPPEPESSITLTPVESAVVAEEHEVVPERPVTCMVSETPAMSA 1293
Query: 63 KSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVST 96
+ T S S + +R+ S VST
Sbjct: 1294 EPTVLASEPPVMSETAETFDSMRASGHVASEVST 1327
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 108 bits (269), Expect = 2e-23
Identities = 93/288 (32%), Positives = 138/288 (47%), Gaps = 30/288 (10%)
Query: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQ---RDHSRSRSPNKARDRSRSRSPYKARD 424
S +SSKE + +S S + P+K+ R HSRSRS ++ R S ++R
Sbjct: 212 SDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRS 271
Query: 425 RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERD 484
RSR RS +K+R RS+SP + R SR R RSRS +K RD+ + KE+
Sbjct: 272 RSRRRSHSKSRSRRRSKSPRRRRSHSRERG-------RRSRSTSKTRDKKKE---DKEKK 321
Query: 485 HSQLGSPSKERDHRRSRSPSKERQCRQSRSSS----KERDHRR--SRSPSKERQRRQSRS 538
S+ P RRSRS S+ER+ R+SRS + K R +R SRSPS R +++ +
Sbjct: 322 RSKT-PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK- 379
Query: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRS 598
K++D+ +SR E ++ +S KE+DR R +S S + ++ +R EE S
Sbjct: 380 --KDKDKERSRDERERSTSKKKKSKDKEKDRER-KSESDKDVKQVTRDYDEEEQGYDSEK 436
Query: 599 PNK------QSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD 640
K ++G + + S EK S SK SD
Sbjct: 437 EKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD 484
Score = 97.8 bits (242), Expect = 3e-20
Identities = 78/269 (28%), Positives = 123/269 (45%), Gaps = 32/269 (11%)
Query: 328 RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKES 387
RHS+SRS S+ + RTP R H SR+ S+ RSHS SRS + + R S +E
Sbjct: 247 RHSRSRSRSRRR-----RTPSSSR-HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
Query: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
GR RSRS +K RD+ + + +++ RS++P K+ +R RS +R
Sbjct: 301 GR-------------RSRSTSKTRDKKK-----EDKEKKRSKTPPKSYSTAR-RSRSASR 341
Query: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
+R R RS + R + RSP R SRSPS R + K++D RSR +
Sbjct: 342 ERRRRRSRSGTRSPKKPRSPK----RKLSRSPSPRRHKKE---KKKDKDKERSRDERERS 394
Query: 508 QCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKER 567
++ +S KE+D R K+ ++ +E+ + EE++ ++ SP +
Sbjct: 395 TSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKE 454
Query: 568 DRRRWRSPSKERERRQSRSSSEERDHSRS 596
+ RE + + E D S
Sbjct: 455 CSVEKGTGDSLRESKVNGDDHHEEDMDMS 483
Score = 97.1 bits (240), Expect = 5e-20
Identities = 81/307 (26%), Positives = 130/307 (42%), Gaps = 34/307 (11%)
Query: 248 MIIPSREKSYSPTEMSSRVKSYNQA----STRSRPQSHSQSRSPRRSRSGSQKRTHSRVR 303
++ PS + S E+ +K +A S P + R RSRS S++R
Sbjct: 205 LVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSS 264
Query: 304 SHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER 363
H +R+ SR+R RSHSK +S+ +S++PRR RSH S+ER
Sbjct: 265 RH--RRSRSRSR----------------RRSHSKSRSRRRSKSPRRRRSH------SRER 300
Query: 364 SHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKAR 423
SRS+SK RD + +K S +R S SR + R RS +RSP K R
Sbjct: 301 GR-RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359
Query: 424 D--RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSK 481
R SRSP+ R + K +D+ RSR + + +S +K +DR R K
Sbjct: 360 SPKRKLSRSPSPRR---HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK 416
Query: 482 ERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNK 541
+ +E+ + + +E++ ++ S + + R+ + + +
Sbjct: 417 DVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHH 476
Query: 542 ERDRSQS 548
E D S
Sbjct: 477 EEDMDMS 483
Score = 91.7 bits (226), Expect = 2e-18
Identities = 72/241 (29%), Positives = 115/241 (47%), Gaps = 32/241 (13%)
Query: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
K R SRS +++R R R+P+ +R R RSRS S+ R HS K R RRS+SP
Sbjct: 242 KEEKRRHSRSRSRSR---RRRTPSSSRHR-RSRSRSRRRSHS------KSRSRRRSKSPR 291
Query: 505 KER-----QCRQSRSSSKERD-------HRRSRSPSK-----ERQRRQSRSPNKERDRSQ 547
+ R + R+SRS+SK RD +RS++P K R R SR + R RS
Sbjct: 292 RRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG 351
Query: 548 SRSPSEER--EHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGY 605
+RSP + R + + SRSPS RR + K++++ +SR E + +S +K+
Sbjct: 352 TRSPKKPRSPKRKLSRSPS---PRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDR 408
Query: 606 SRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQN 665
R S K+ +E + + +E P ++ P++ + SL ++
Sbjct: 409 ERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRES 468
Query: 666 R 666
+
Sbjct: 469 K 469
Score = 74.7 bits (182), Expect = 3e-13
Identities = 71/231 (30%), Positives = 108/231 (46%), Gaps = 27/231 (11%)
Query: 488 LGSPSKERDHRRSRSPSKERQCRQSRS---SSKERDHRRSRSPSKERQRRQSRSPNKERD 544
L SPS + D ++ R+++S ++ E D KE +RR SRS ++ R
Sbjct: 205 LVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPD-------KKEEKRRHSRSRSRSRR 257
Query: 545 RSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604
R R+PS R HR+SRS R R RS SK R RR+S+S R HSR R +S
Sbjct: 258 R---RTPSSSR-HRRSRS------RSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRST 307
Query: 605 YSRPRASSKEKAHSRSRTPSKE-GNHSQSRTSSKESDPSQS-TVPRSPDWKRSPTRTSSL 662
++K RS+TP K +SR++S+E +S + RSP RSP R L
Sbjct: 308 SKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKR--KL 365
Query: 663 SQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713
S++ +P + H + S+D+ + + K + E+ S+
Sbjct: 366 SRSPSPRR---HKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE 413
Score = 72.8 bits (177), Expect = 1e-12
Identities = 73/284 (25%), Positives = 115/284 (40%), Gaps = 34/284 (11%)
Query: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTH 299
R+ +S I +K SR +S + + S S+SRS RRS S S+ R
Sbjct: 227 REAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRR 286
Query: 300 SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNP 359
S +S +R+HSR R GR S+S S ++ K + R S+ P
Sbjct: 287 S--KSPRRRRSHSRER-----------GRRSRSTSKTRDKKKEDKEKKR-------SKTP 326
Query: 360 SKERSHS-HSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSR--SRSPNKARDRSRS 416
K S + SRS+S+ER R+ RS + SP K R R SRSP+ R +
Sbjct: 327 PKSYSTARRSRSASRER--------RRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEK 378
Query: 417 RSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRS 476
+ K +D+ RSR + + +S K +DR R +K + +
Sbjct: 379 K---KDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSE 435
Query: 477 RSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD 520
+ +E+ + GSP + + R+ + + E D
Sbjct: 436 KEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEED 479
Score = 58.2 bits (139), Expect = 3e-08
Identities = 65/279 (23%), Positives = 104/279 (37%), Gaps = 30/279 (10%)
Query: 22 PTADPK------PPASLKSTKSATPN----RSLVPTKPATSRNSVMSPSSSKSTKSTSTK 71
PT DP P A+L S A S V K ++SPS T S +
Sbjct: 161 PTLDPALAALGLPGANLNSQSLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIE 220
Query: 72 RAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRS 131
A ++S + S A P + R S++ S R H R R+ RR S S
Sbjct: 221 EAMKRVREAQSLI-SAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHS 279
Query: 132 SKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNL 191
RS R+ +P R R+H S+++G R +S + R +E + +
Sbjct: 280 KSRSRRRSKSPRRRRSH--------------SRERGRRSRSTSKTRDKKKEDKEKKRSKT 325
Query: 192 SKKSYRPPGGS-GIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMII 250
KSY S R + S + P ++ S +PSP +K K +
Sbjct: 326 PPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDK--- 382
Query: 251 PSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRR 289
+E+S E S+ K ++ + R + + ++
Sbjct: 383 -DKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQ 420
Score = 47.8 bits (112), Expect = 4e-05
Identities = 94/397 (23%), Positives = 140/397 (35%), Gaps = 95/397 (23%)
Query: 14 LAPSGSSMPTADPKPPAS---LKSTKSATPNRSLVPTK-PATSRNSVMSPSSSKSTKSTS 69
L P G +PT +P L + + T + +L P + NS S ++ + K S
Sbjct: 134 LLPGGGLLPTPNPLTQIGAVPLAALGAPTLDPALAALGLPGANLNS-QSLAADQLLKLMS 192
Query: 70 TKRAPSNR-------PSSRSRVRSKA--RTPSRVSTDTRTSKASKASDVRCHQRRGTHSR 120
T N PS +S SK RV A+ D + +RR + SR
Sbjct: 193 TVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSR 252
Query: 121 GRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSN 180
R+ RR SS+ SR+ + R R+H S+ +S R ++
Sbjct: 253 SRSRRRRTPSSSRHRRSRSRS--RRRSH-------------------SKSRSRRRSKSPR 291
Query: 181 RERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSR 240
R RS S+ R GR S ST+K + K+K D S
Sbjct: 292 RRRSHSRER---------------GRRSR-----STSKTR------DKKKEDKEKKRSKT 325
Query: 241 KVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSG--SQKRT 298
KSY ST R +S S+ R RRSRSG S K+
Sbjct: 326 PPKSY---------------------------STARRSRSASRERRRRRSRSGTRSPKKP 358
Query: 299 HSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRN 358
S R S + R + +K + R + RS SK K R +S +
Sbjct: 359 RSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSES---- 414
Query: 359 PSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSP 395
K+ +E+ + ++E ++GSP
Sbjct: 415 -DKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSP 450
Score = 33.9 bits (76), Expect = 0.54
Identities = 30/127 (23%), Positives = 47/127 (37%), Gaps = 11/127 (8%)
Query: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPA----------TS 52
SP+R S S K + +S TP +S + + S
Sbjct: 289 SPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRS 348
Query: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH 112
R+ SP +S K R+PS R + + + K + SR + TSK K+ D
Sbjct: 349 RSGTRSPKKPRSPK-RKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKD 407
Query: 113 QRRGTHS 119
+ R + S
Sbjct: 408 RERKSES 414
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 105 bits (262), Expect = 1e-22
Identities = 112/380 (29%), Positives = 168/380 (44%), Gaps = 53/380 (13%)
Query: 292 SGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGR 351
SGS++ + + N S RS + KG L + ++ SK +S+ ++R +
Sbjct: 142 SGSEEE--GEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKK 199
Query: 352 SHNWSRNPSKE---RSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPN 408
KE RS S R SK R S + +S + Q ++RSP
Sbjct: 200 KSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPT 259
Query: 409 KARDRSRSRSPYKARDRSRSRSPNKARDCSR---SRSPYKARDRSRSR-SPNKARDHSRS 464
+ + +S K++DR +S N++R R SRSP R +S+ R S +K R RS
Sbjct: 260 DDKVKIEDKS--KSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRS 317
Query: 465 ---------RSPNK-----ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS-KERQC 509
+SP+K +RS SR P + L SP RRSRSP +R+
Sbjct: 318 ETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSL-SPKPRDKSRRSRSPLLNDRRS 376
Query: 510 RQSRSSSKERDH-RRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRS------ 562
+QS+S S+ RR++S S ER+RR+ P + R S P ++ R+ RS
Sbjct: 377 KQSKSPSRTLSPGRRAKSRSLERKRRE---PERRRLSSPRTRPRDDILSRRERSKDASPI 433
Query: 563 ----PSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHS 618
P+ RRR RSP + R R R S R RSRSP ++ R R+ + ++ S
Sbjct: 434 NRWSPT----RRRSRSPIRRRSRSPLRRSRSPR--RRSRSPRRRDRGRRSRSRLRRRSRS 487
Query: 619 RSRTPSKEGNHSQSRTSSKE 638
R G +SR+ KE
Sbjct: 488 RG------GRRRRSRSKVKE 501
Score = 103 bits (257), Expect = 6e-22
Identities = 143/465 (30%), Positives = 221/465 (47%), Gaps = 66/465 (14%)
Query: 229 EKSDNPSPSSSRKVKSYGQMI-----IPSREKSYSPTEMSSRVKSYNQAS---------- 273
EK+ N + SS+R + G++ I ++++S S ++ +R +S + S
Sbjct: 152 EKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEK 211
Query: 274 -TRSRPQSHSQSRSP-RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQ 331
TRS+ + +S+SP +RS+S Q R + +S + +R + R ++ +
Sbjct: 212 TTRSKSKERKKSKSPSKRSKSQDQAR---KSKSPTLRRRSQEKIGKARSPTDDKVKIEDK 268
Query: 332 SRSHSKGKSQ--NQSRTPRRGRSHNWSRNPSKERSHSHSRSS-SKERDHRGSSSPRKES- 387
S+S + KS N+SR+ RG+ SR+P R S R S SKER + S + +++
Sbjct: 269 SKSKDRKKSPIINESRSRDRGKK---SRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKP 325
Query: 388 --GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSR-SRSPN-KARDCSRSRSP 443
S+ S K+ + S SR P ++ R RS SP K RD+SR SRSP R +S+SP
Sbjct: 326 IKSPSKDASSGKE-NRSPSRRPGRSPKR-RSLSP-KPRDKSRRSRSPLLNDRRSKQSKSP 382
Query: 444 YKARD---RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERD--HR 498
+ R++SRS + R R + R R R S+ R+ S+ SP R
Sbjct: 383 SRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSR-RERSKDASPINRWSPTRR 441
Query: 499 RSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHR 558
RSRSP + R+SRS RRSRSP RR+SRSP + RDR + S R R
Sbjct: 442 RSRSPIR----RRSRSPL-----RRSRSP-----RRRSRSPRR-RDRGRR---SRSRLRR 483
Query: 559 QSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHS 618
+SR S+ RRR RS KE + + S S + + S N + E+A
Sbjct: 484 RSR--SRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLE---DFDVEEEDEEALI 538
Query: 619 RSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLS 663
R ++ + + +++S+ S VP P +S TRT S S
Sbjct: 539 EQRRIQRQAIVQKYKYLAEDSNMS---VPSEPSSPQSSTRTRSPS 580
Score = 95.5 bits (236), Expect = 2e-19
Identities = 115/462 (24%), Positives = 193/462 (41%), Gaps = 101/462 (21%)
Query: 316 SRTRKGILSQMGRHSQSRSHSKG----KSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
+ + K I + G S+ +S +K K +++ R+ + H+ + K+ H H
Sbjct: 18 ANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKK 77
Query: 372 SKER------DHRGSSSPRK--------------------------------ESGRS--- 390
K + D G S ++ +SG
Sbjct: 78 HKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLIL 137
Query: 391 ---QSGSPNKQRDHSRSRSPNKARDRSRSRS------PYKARDRSRSRSPNKARDCSRSR 441
+SGS + H ++R+ N++ RS S K + RS+S +K R RS
Sbjct: 138 QGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRS- 196
Query: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRR-- 499
D+ +S+ + +RS K+++R +S+SPSK SK RR
Sbjct: 197 ------DKKKSKGGIEIVKEKTTRS--KSKERKKSKSPSKRSKSQDQARKSKSPTLRRRS 248
Query: 500 ------SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQR-RQSRSPNKERDRSQS-RSP 551
+RSP+ ++ + +S SK+R + S+ R R ++SRSP R +S+ RS
Sbjct: 249 QEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSR 308
Query: 552 SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSR--SRSPNKQSGYSRPR 609
S+ER+ ++S + +++++ +SPSK+ + S E R SR RSP ++S +PR
Sbjct: 309 SKERKSKRSET---DKEKKPIKSPSKD-----ASSGKENRSPSRRPGRSPKRRSLSPKPR 360
Query: 610 ASSKEKAHSRSRTPSKEGNHS-QSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTP 668
S+ RSR+P S QS++ S+ P + RS + KR R P
Sbjct: 361 DKSR-----RSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKR-----------REP 404
Query: 669 SKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSS 710
+ SP T P LS+ + DA+ P R S S
Sbjct: 405 ERRRLSSPRTRPR-DDILSRRERSKDASPINRWSPTRRRSRS 445
Score = 93.6 bits (231), Expect = 6e-19
Identities = 155/612 (25%), Positives = 235/612 (38%), Gaps = 112/612 (18%)
Query: 50 ATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDV 109
A S S+ + S + K S + + RSK + S + + K
Sbjct: 18 ANSEKSINEENGEVSEDQSQNKH--SRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKH 75
Query: 110 RCHQRR----GTHSRGRTPGRRGSRSS---------KRSPSRASTPGRIRTHGARPGMAS 156
+ H+R+ + G +P +R +R+ +A + + GM
Sbjct: 76 KKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGL 135
Query: 157 RVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPST 216
++ S + G+ + + R NR S R+ S K EL T
Sbjct: 136 ILQGYESGSE-EEGEIHEKARNGNR----SSTRSSSTKG-----------KLELVDNKIT 179
Query: 217 AKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMII----------PSREKSYSPTEMSSRV 266
K + SK +S + S K KS G + I R+KS SP S R
Sbjct: 180 TKKR------SKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSP---SKRS 230
Query: 267 KSYNQASTRSRPQSHSQS-------RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTR 319
KS +QA P +S RSP + + ++ S+ R S N SR+R R +
Sbjct: 231 KSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGK 290
Query: 320 KGI--LSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH 377
K + G+ RS SK + +S T + + ++PSK+ S S R
Sbjct: 291 KSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKP---IKSPSKDASSGKENRSPSRRPG 347
Query: 378 RG------SSSPRKESGRSQSGSPNKQRDHSRSRSPNKARD---RSRSRSPYKAR---DR 425
R S PR +S RS+S N +R +S+SP++ R++SRS + R +R
Sbjct: 348 RSPKRRSLSPKPRDKSRRSRSPLLNDRRS-KQSKSPSRTLSPGRRAKSRSLERKRREPER 406
Query: 426 SRSRSPN--------KARDCSRSRSPYK--ARDRSRSRSPNKARDHS---RSRSPNKARD 472
R SP R+ S+ SP + R RSRSP + R S RSRSP + R
Sbjct: 407 RRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRR-RS 465
Query: 473 RSRSRSPSKERDHSQLGSPSKERD--HRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKE 530
RS R R S+L S+ R RRSRS KE + + S S + + S + E
Sbjct: 466 RSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLE 525
Query: 531 -------------RQRRQSRSP--------NKERDRSQSRSPSEEREHRQSRSPSKERDR 569
QRR R ++ + S PS + ++RSPS +
Sbjct: 526 DFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDIL 585
Query: 570 RRWRSPSKERER 581
R + KE ER
Sbjct: 586 ERVAADVKEYER 597
Score = 77.4 bits (189), Expect = 4e-14
Identities = 135/525 (25%), Positives = 191/525 (36%), Gaps = 115/525 (21%)
Query: 19 SSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS-------KSTKSTSTK 71
SS ++ K L K T RS +K T S S K+T+S S +
Sbjct: 160 SSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKE 219
Query: 72 RAPSNRPSSRSRVRSKARTPSRVSTDTRT-SKASKASDVRCHQRRGTHSRGRTPGRRGSR 130
R S PS RS+ + +AR + R+ K KA R T + + + S+
Sbjct: 220 RKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKA-------RSPTDDKVKIEDKSKSK 272
Query: 131 SSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRN 190
K+SP + R R + R+P RGKS R R+ ++ER
Sbjct: 273 DRKKSPIINESRSRDR--------GKKSRSPVD----LRGKSKDR-RSRSKERK------ 313
Query: 191 LSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMII 250
SK+S T K + P PSK+ S S
Sbjct: 314 -SKRS-------------------ETDKEKKPIKSPSKDASSGKENRS------------ 341
Query: 251 PSREKSYSPTEMS----SRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQK---RTHSRVR 303
PSR SP S R KS S + QS+SP R+ S ++ R+ R R
Sbjct: 342 PSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKR 401
Query: 304 SHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER 363
+R S R+R R ILS+ R SK S +P R R SR+P + R
Sbjct: 402 REPERRRLSSPRTRPRDDILSR-------RERSKDASPINRWSPTRRR----SRSPIRRR 450
Query: 364 SHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKAR 423
S S R S R R S SPR+ RD R RS ++ R RSRSR + R
Sbjct: 451 SRSPLRRSRSPR--RRSRSPRR-------------RDRGR-RSRSRLRRRSRSRGGRRRR 494
Query: 424 DRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRS------- 476
RS+ + S + S S + D +A R
Sbjct: 495 SRSKVKEDKFKGSLSEG-----MKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIV 549
Query: 477 ---RSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
+ +++ + S PS + R+RSPS + + + KE
Sbjct: 550 QKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKE 594
Score = 43.1 bits (100), Expect = 9e-04
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 17/148 (11%)
Query: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS 62
SPK K S +P + + K P+ S +RSL + R + SP +
Sbjct: 356 SPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTR 415
Query: 63 K-----STKSTSTKRAPSNRPS-----SRSRVRSKARTPSRVS-TDTRTSKASKASDVRC 111
S + S +P NR S SRS +R ++R+P R S + R S++ + D
Sbjct: 416 PRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRD--- 472
Query: 112 HQRRGTHSRGRTPGRRGSRSSKRSPSRA 139
RG SR R R SR +R SR+
Sbjct: 473 ---RGRRSRSRLRRRSRSRGGRRRRSRS 497
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 104 bits (260), Expect = 2e-22
Identities = 114/417 (27%), Positives = 163/417 (39%), Gaps = 58/417 (13%)
Query: 336 SKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHR-------GSSSPRKESG 388
S G + S T RRG R P ++R S RS + R+HR GS + + S
Sbjct: 177 SGGSPASSSGTQRRGEGSE--RRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSR 234
Query: 389 RSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARD 448
S SG + S S S + R +S S + S S S K RD RS K+
Sbjct: 235 HSHSGEERAEVAKSGSSSSSGGRRKSASAT-------SSSSSSRKDRDSKAHRSRTKSSK 287
Query: 449 RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508
S + + ++ KA R RS SP RD S + HR S+S +
Sbjct: 288 EPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVS-------HRASQSLRSRKS 340
Query: 509 CRQSRSSSKERDHRRSRSPSKERQRRQ---SRSPNKERDRSQSRSPSEEREHRQSRSPSK 565
+ S R RSPS +RR SR + ER S SP R+SRSP
Sbjct: 341 PSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYS 400
Query: 566 ERDRRRWRSPSKE-RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624
RR +S S+ R SRS S R SRSRS + S S A +
Sbjct: 401 PVLRRSGKSRSRSPYSSRHSRSRSRHR-LSRSRSRHSSISPSTLTLKSSLAAELNKNKKA 459
Query: 625 KEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTS------------ 672
+ +++ ++K ++ +++ + K S T T + T + S
Sbjct: 460 RAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIK 519
Query: 673 -SHSPSTFPSGGQTLSQDDSQ---------------ADATTSKATLPGERSSSSSSK 713
H+PS PS G TL D ++ D T KA + G+ S S+++K
Sbjct: 520 IEHAPS--PSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAVIVGKESKSAATK 574
Score = 80.5 bits (197), Expect = 5e-15
Identities = 91/340 (26%), Positives = 134/340 (39%), Gaps = 51/340 (15%)
Query: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
G S S ++R R P + R S RS + R+ R + S+SRS +
Sbjct: 179 GSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHS 238
Query: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
R+ A+ S S S + + S + S S R K+RD + RS +K
Sbjct: 239 GEERAEV---AKSGSSSSSGGRRKSASATSSSSSSR---------KDRDSKAHRSRTKSS 286
Query: 508 QCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQ-SRSPSEEREHRQSRSP--- 563
+ S + +R ++ K +RR+S SP RD S S S+ R+S SP
Sbjct: 287 KEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG 346
Query: 564 -SKERDRRRWRSPSKERERRQ---SRSSSEERDHSRSRSPNKQSGYSRPRASS----KEK 615
S RR RSPS RR SR SS ER S SP S + R R+ +
Sbjct: 347 GSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRS 406
Query: 616 AHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHS 675
SRSR+P HS+SR+ + S R+ S+ SS S
Sbjct: 407 GKSRSRSPYSS-RHSRSRSRHRLS--------------------------RSRSRHSSIS 439
Query: 676 PSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKLA 715
PST ++ + A ++A E + ++ + A
Sbjct: 440 PSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKA 479
Score = 65.5 bits (158), Expect = 2e-10
Identities = 83/370 (22%), Positives = 150/370 (40%), Gaps = 27/370 (7%)
Query: 58 SPSSSKSTKST---STKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH-- 112
SP+SS T+ S +R +R SS R + + R R S+ASK+ H
Sbjct: 180 SPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSG 239
Query: 113 QRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKS 172
+ R ++ + G R S + +S+ R R A R RT +S++ S +
Sbjct: 240 EERAEVAKSGSSSSSGGRRKSASATSSSSSSR----KDRDSKAHRSRTKSSKEPPS---A 292
Query: 173 YGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELA-VTPSTAKCQTPTGIPSKEKS 231
Y P + RE ++S P GG S A + + K +P G S S
Sbjct: 293 YKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYS 352
Query: 232 ----DNPSPSSSRKVKSYGQMIIPSR--EKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR 285
+PSP S R+ SY + R + S SP SS +S + S R S+SR
Sbjct: 353 RRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSR 412
Query: 286 SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR 345
SP SR + H RS S + S + + + +++ ++ ++R+ ++ ++
Sbjct: 413 SPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAK 472
Query: 346 TPR-------RGRSHNWSRNPSKERSHSHSRSSSKERDH-RGSSSPRKESGRSQSGSPNK 397
++ S + + ++ + +S+ + +H + + E S S
Sbjct: 473 AAEATKAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTL 532
Query: 398 QRDHSRSRSP 407
+ D ++++ P
Sbjct: 533 KNDKAKTKPP 542
Score = 63.9 bits (154), Expect = 5e-10
Identities = 106/425 (24%), Positives = 165/425 (38%), Gaps = 56/425 (13%)
Query: 128 GSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQ 187
G+ S SP+ +S R R G+ R P ++ S G+S R R +R R +
Sbjct: 173 GTGGSGGSPASSSGTQR-RGEGSE-------RRPRRDRRSSSGRSKERHR-EHRRRDGQR 223
Query: 188 PRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQ 247
+ + KS SG R+ E+A + S++ +G K S S SSSRK +
Sbjct: 224 GGSEASKSRSRHSHSGEERA-EVAKSGSSSS----SGGRRKSASATSSSSSSRKDRDSKA 278
Query: 248 MIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSW 307
++ P+ K+Y + T + +S SP R S SH
Sbjct: 279 HRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPV-------SHR- 330
Query: 308 KRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367
SQ R +S S + G S SR R S S+ RS S+
Sbjct: 331 ---------------ASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPY-----SRRRSPSY 370
Query: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARD-RSRSRSPYKARDRS 426
SR SS ER S SP S +S SP SP R +SRSRSPY +R S
Sbjct: 371 SRHSSYERGGDVSPSPYSSSSWRRSRSP---------YSPVLRRSGKSRSRSPYSSR-HS 420
Query: 427 RSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHS 486
RSRS ++ SRSRS + + S + +A + +R+ +K + +
Sbjct: 421 RSRSRHR---LSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAT 477
Query: 487 QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS 546
+ + + + S + S S+S+ + + E S + D++
Sbjct: 478 KAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKA 537
Query: 547 QSRSP 551
+++ P
Sbjct: 538 KTKPP 542
Score = 39.7 bits (91), Expect = 0.010
Identities = 57/249 (22%), Positives = 94/249 (37%), Gaps = 26/249 (10%)
Query: 48 KPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKAS 107
K +S +S S+ +T S+S+ R + + RSR +S PS + + K
Sbjct: 247 KSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTE 306
Query: 108 DVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKG 167
+RR G GR S S R+ + G SR R P S
Sbjct: 307 PKAYRRRRSLSPLG---GRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSR-RLPRSPSPY 362
Query: 168 SRGKSYGRPRTSNRER-SDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIP 226
SR +S R S+ ER D P S S+ R S +P +
Sbjct: 363 SRRRSPSYSRHSSYERGGDVSPSPYSSSSW---------RRSRSPYSPVLRR-------- 405
Query: 227 SKEKSDNPSPSSSRKVKSYGQMIIP---SREKSYSPTEMSSRVKSYNQASTRSRPQSHSQ 283
KS + SP SSR +S + + SR S SP+ ++ + + + + ++
Sbjct: 406 -SGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEA 464
Query: 284 SRSPRRSRS 292
+R+ +++
Sbjct: 465 ARAAEAAKA 473
Score = 38.5 bits (88), Expect = 0.022
Identities = 52/198 (26%), Positives = 77/198 (38%), Gaps = 24/198 (12%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATP----NRSLVPTKPATSRNSVM 57
S R SK S S P+A +PP + + K+ RSL P R+
Sbjct: 270 SRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSL---SPLGGRDD-- 324
Query: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGT 117
SP S ++++S ++++PS P+ R P S +R S + R +
Sbjct: 325 SPVSHRASQSLRSRKSPS--PAGGGSSPYSRRLPRSPSPYSRRRSPS-------YSRHSS 375
Query: 118 HSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPR 177
+ RG SS SR+ +R G SR R+P S + SR +S R
Sbjct: 376 YERGGDVSPSPYSSSSWRRSRSPYSPVLRRSG-----KSRSRSPYS-SRHSRSRSRHRLS 429
Query: 178 TSNRERSDSQPRNLSKKS 195
S S P L+ KS
Sbjct: 430 RSRSRHSSISPSTLTLKS 447
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 104 bits (260), Expect = 2e-22
Identities = 114/417 (27%), Positives = 163/417 (39%), Gaps = 58/417 (13%)
Query: 336 SKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHR-------GSSSPRKESG 388
S G + S T RRG R P ++R S RS + R+HR GS + + S
Sbjct: 177 SGGSPASSSGTQRRGEGSE--RRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSR 234
Query: 389 RSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARD 448
S SG + S S S + R +S S + S S S K RD RS K+
Sbjct: 235 HSHSGEERAEVAKSGSSSSSGGRRKSASAT-------SSSSSSRKDRDSKAHRSRTKSSK 287
Query: 449 RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508
S + + ++ KA R RS SP RD S + HR S+S +
Sbjct: 288 EPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVS-------HRASQSLRSRKS 340
Query: 509 CRQSRSSSKERDHRRSRSPSKERQRRQ---SRSPNKERDRSQSRSPSEEREHRQSRSPSK 565
+ S R RSPS +RR SR + ER S SP R+SRSP
Sbjct: 341 PSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYS 400
Query: 566 ERDRRRWRSPSKE-RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624
RR +S S+ R SRS S R SRSRS + S S A +
Sbjct: 401 PVLRRSGKSRSRSPYSSRHSRSRSRHR-LSRSRSRHSSISPSTLTLKSSLAAELNKNKKA 459
Query: 625 KEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTS------------ 672
+ +++ ++K ++ +++ + K S T T + T + S
Sbjct: 460 RAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIK 519
Query: 673 -SHSPSTFPSGGQTLSQDDSQ---------------ADATTSKATLPGERSSSSSSK 713
H+PS PS G TL D ++ D T KA + G+ S S+++K
Sbjct: 520 IEHAPS--PSSGGTLKNDKAKTKPPLQVTKVENNLIVDKATKKAVIVGKESKSAATK 574
Score = 80.5 bits (197), Expect = 5e-15
Identities = 91/340 (26%), Positives = 134/340 (39%), Gaps = 51/340 (15%)
Query: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
G S S ++R R P + R S RS + R+ R + S+SRS +
Sbjct: 179 GSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHS 238
Query: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
R+ A+ S S S + + S + S S R K+RD + RS +K
Sbjct: 239 GEERAEV---AKSGSSSSSGGRRKSASATSSSSSSR---------KDRDSKAHRSRTKSS 286
Query: 508 QCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQ-SRSPSEEREHRQSRSP--- 563
+ S + +R ++ K +RR+S SP RD S S S+ R+S SP
Sbjct: 287 KEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG 346
Query: 564 -SKERDRRRWRSPSKERERRQ---SRSSSEERDHSRSRSPNKQSGYSRPRASS----KEK 615
S RR RSPS RR SR SS ER S SP S + R R+ +
Sbjct: 347 GSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRS 406
Query: 616 AHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHS 675
SRSR+P HS+SR+ + S R+ S+ SS S
Sbjct: 407 GKSRSRSPYSS-RHSRSRSRHRLS--------------------------RSRSRHSSIS 439
Query: 676 PSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSKLA 715
PST ++ + A ++A E + ++ + A
Sbjct: 440 PSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKA 479
Score = 65.5 bits (158), Expect = 2e-10
Identities = 83/370 (22%), Positives = 150/370 (40%), Gaps = 27/370 (7%)
Query: 58 SPSSSKSTKST---STKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH-- 112
SP+SS T+ S +R +R SS R + + R R S+ASK+ H
Sbjct: 180 SPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSG 239
Query: 113 QRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKS 172
+ R ++ + G R S + +S+ R R A R RT +S++ S +
Sbjct: 240 EERAEVAKSGSSSSSGGRRKSASATSSSSSSR----KDRDSKAHRSRTKSSKEPPS---A 292
Query: 173 YGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELA-VTPSTAKCQTPTGIPSKEKS 231
Y P + RE ++S P GG S A + + K +P G S S
Sbjct: 293 YKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYS 352
Query: 232 ----DNPSPSSSRKVKSYGQMIIPSR--EKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR 285
+PSP S R+ SY + R + S SP SS +S + S R S+SR
Sbjct: 353 RRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSR 412
Query: 286 SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR 345
SP SR + H RS S + S + + + +++ ++ ++R+ ++ ++
Sbjct: 413 SPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAK 472
Query: 346 TPR-------RGRSHNWSRNPSKERSHSHSRSSSKERDH-RGSSSPRKESGRSQSGSPNK 397
++ S + + ++ + +S+ + +H + + E S S
Sbjct: 473 AAEATKAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTL 532
Query: 398 QRDHSRSRSP 407
+ D ++++ P
Sbjct: 533 KNDKAKTKPP 542
Score = 63.9 bits (154), Expect = 5e-10
Identities = 106/425 (24%), Positives = 165/425 (38%), Gaps = 56/425 (13%)
Query: 128 GSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQ 187
G+ S SP+ +S R R G+ R P ++ S G+S R R +R R +
Sbjct: 173 GTGGSGGSPASSSGTQR-RGEGSE-------RRPRRDRRSSSGRSKERHR-EHRRRDGQR 223
Query: 188 PRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQ 247
+ + KS SG R+ E+A + S++ +G K S S SSSRK +
Sbjct: 224 GGSEASKSRSRHSHSGEERA-EVAKSGSSSS----SGGRRKSASATSSSSSSRKDRDSKA 278
Query: 248 MIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSW 307
++ P+ K+Y + T + +S SP R S SH
Sbjct: 279 HRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPV-------SHR- 330
Query: 308 KRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367
SQ R +S S + G S SR R S S+ RS S+
Sbjct: 331 ---------------ASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPY-----SRRRSPSY 370
Query: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARD-RSRSRSPYKARDRS 426
SR SS ER S SP S +S SP SP R +SRSRSPY +R S
Sbjct: 371 SRHSSYERGGDVSPSPYSSSSWRRSRSP---------YSPVLRRSGKSRSRSPYSSR-HS 420
Query: 427 RSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHS 486
RSRS ++ SRSRS + + S + +A + +R+ +K + +
Sbjct: 421 RSRSRHR---LSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAT 477
Query: 487 QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRS 546
+ + + + S + S S+S+ + + E S + D++
Sbjct: 478 KAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKA 537
Query: 547 QSRSP 551
+++ P
Sbjct: 538 KTKPP 542
Score = 39.7 bits (91), Expect = 0.010
Identities = 57/249 (22%), Positives = 94/249 (37%), Gaps = 26/249 (10%)
Query: 48 KPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKAS 107
K +S +S S+ +T S+S+ R + + RSR +S PS + + K
Sbjct: 247 KSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTE 306
Query: 108 DVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKG 167
+RR G GR S S R+ + G SR R P S
Sbjct: 307 PKAYRRRRSLSPLG---GRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSR-RLPRSPSPY 362
Query: 168 SRGKSYGRPRTSNRER-SDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIP 226
SR +S R S+ ER D P S S+ R S +P +
Sbjct: 363 SRRRSPSYSRHSSYERGGDVSPSPYSSSSW---------RRSRSPYSPVLRR-------- 405
Query: 227 SKEKSDNPSPSSSRKVKSYGQMIIP---SREKSYSPTEMSSRVKSYNQASTRSRPQSHSQ 283
KS + SP SSR +S + + SR S SP+ ++ + + + + ++
Sbjct: 406 -SGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEA 464
Query: 284 SRSPRRSRS 292
+R+ +++
Sbjct: 465 ARAAEAAKA 473
Score = 38.5 bits (88), Expect = 0.022
Identities = 52/198 (26%), Positives = 77/198 (38%), Gaps = 24/198 (12%)
Query: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATP----NRSLVPTKPATSRNSVM 57
S R SK S S P+A +PP + + K+ RSL P R+
Sbjct: 270 SRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSL---SPLGGRDD-- 324
Query: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGT 117
SP S ++++S ++++PS P+ R P S +R S + R +
Sbjct: 325 SPVSHRASQSLRSRKSPS--PAGGGSSPYSRRLPRSPSPYSRRRSPS-------YSRHSS 375
Query: 118 HSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPR 177
+ RG SS SR+ +R G SR R+P S + SR +S R
Sbjct: 376 YERGGDVSPSPYSSSSWRRSRSPYSPVLRRSG-----KSRSRSPYS-SRHSRSRSRHRLS 429
Query: 178 TSNRERSDSQPRNLSKKS 195
S S P L+ KS
Sbjct: 430 RSRSRHSSISPSTLTLKS 447
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 103 bits (258), Expect = 4e-22
Identities = 62/235 (26%), Positives = 105/235 (44%), Gaps = 10/235 (4%)
Query: 375 RDHRGSSSPRKESGRSQS----GSPNKQRDHSRSRSPN-KARDRSRSRSPYKARDRSRSR 429
R GS + G Q+ ++QR+ R R K RDR R R + R + +
Sbjct: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRR---KEK 107
Query: 430 SPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLG 489
N+ RD + + R+R + + + RD R R ++ R++ R R K+RD +
Sbjct: 108 ETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRET 167
Query: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
+ERD R + +E + + R E++ R ++RQR+ +E DR R
Sbjct: 168 ETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGER 227
Query: 550 SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSS--SEERDHSRSRSPNKQ 602
RE ++ R KERDR R R +++ER++ R E++ + R K+
Sbjct: 228 ETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 101 bits (251), Expect = 3e-21
Identities = 70/266 (26%), Positives = 115/266 (43%), Gaps = 36/266 (13%)
Query: 336 SKGK--SQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS-KERDHRGSSSPRKESGRSQS 392
S+G+ SQ R+ G++H + ++R R + KERD
Sbjct: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDR--------------- 94
Query: 393 GSPNKQRDHSRSRSPNKA-RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSR 451
+++RD R R + R+R R + RDR R + + R+ R R + RDR +
Sbjct: 95 ---DRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREK 151
Query: 452 SRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQ 511
R +D R R+R R R KER+ ERD R R KER+
Sbjct: 152 ERERQTEKDRDGQRETETERERDREREKQKERE--------TERDRDRQRDTEKERE--- 200
Query: 512 SRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRR 571
R + +ERD R R ERQR R +E DR + R +R + R ++ +R++
Sbjct: 201 -RQTDRERD--RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK 257
Query: 572 WRSPSKERERRQSRSSSEERDHSRSR 597
R +++ER++ + + R+ + +
Sbjct: 258 ERKKERKKERKEKKKEEKRREDKKRK 283
Score = 94.7 bits (234), Expect = 3e-19
Identities = 60/241 (24%), Positives = 106/241 (43%), Gaps = 10/241 (4%)
Query: 400 DHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKAR 459
D SR R ++ RS +A + + RD R ++ K RDR R R + R
Sbjct: 48 DFSRGRLGSQESPRSWGLG--QAHKDADGDDRQRERDRVREKTE-KERDRDRKRDRERRR 104
Query: 460 DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER 519
+ + N+ RDR + ++R+ + +ERD R R ++R+ + R + K+R
Sbjct: 105 ---KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDR 161
Query: 520 DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKER 579
D +R +ER R + + +E +R + R E+E + R +ERDR+ R ER
Sbjct: 162 DGQRETETERERDREREKQKERETERDRDRQRDTEKE--RERQTDRERDRQ--RKTQTER 217
Query: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKES 639
+R R E D R R ++ G R R +++ + R ++ + + K
Sbjct: 218 QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
Query: 640 D 640
+
Sbjct: 278 E 278
Score = 89.7 bits (221), Expect = 8e-18
Identities = 60/248 (24%), Positives = 104/248 (41%), Gaps = 19/248 (7%)
Query: 325 QMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS-KERSHSHSRSSSKERDHRGSSSP 383
++G RS G++ + R R + R + KER R + R + ++
Sbjct: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRN 112
Query: 384 RK-------ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436
R E R + ++R+ R R + RDR + R +DR R R+
Sbjct: 113 RDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE 172
Query: 437 CSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERD 496
R R K R+ R R + + R R ++ RDR R ++R+ + G +E D
Sbjct: 173 RDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE--RETD 230
Query: 497 HRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR-SPNKERDRSQSRSPSEER 555
RR R ++R KERD R R ++++R++ R KE+ + + R ++R
Sbjct: 231 RRRERQRDRDR--------GKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
Query: 556 EHRQSRSP 563
+ + SP
Sbjct: 283 KWGEGISP 290
Score = 87.0 bits (214), Expect = 5e-17
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 6/239 (2%)
Query: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
SR +++ RS +A + + RDR R ++ K RD R R + R +
Sbjct: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKT-EKERDRDRKRDRERRR---K 105
Query: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ 535
+ ++ RD + ERD R + +ER+ + R ++RD + R E+ R
Sbjct: 106 EKETNRNRDREK--QTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDG 163
Query: 536 SRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSR 595
R ER+R + R +ERE + R ++ ++ R R +ER+R++ + +R+ R
Sbjct: 164 QRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR 223
Query: 596 SRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKR 654
R R + K R R +E + + KE + R D KR
Sbjct: 224 EGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 80.9 bits (198), Expect = 4e-15
Identities = 65/274 (23%), Positives = 111/274 (40%), Gaps = 35/274 (12%)
Query: 268 SYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMG 327
S + ++ P+S ++ + + ++R RVR + K R R RK
Sbjct: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKE-----RDRDRK------- 97
Query: 328 RHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKES 387
R + R K ++N+ R + + R K R R +ERD ++
Sbjct: 98 RDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERD--------RDR 149
Query: 388 GRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKAR 447
+ + K RD R + RDR R + K R+ R R + + R R + R
Sbjct: 150 EKERERQTEKDRDGQRETETERERDREREKQ--KERETERDRDRQRDTEKERERQTDRER 207
Query: 448 DRSRSRSPNKARDHSR--SRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSK 505
DR R + R+ R R ++ R+R R R KERD +ERD + R +
Sbjct: 208 DRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERD--------RERDRKEERKKER 259
Query: 506 ERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP 539
+++ ++ R K+ + RR K+R+ + SP
Sbjct: 260 KKERKKERKEKKKEEKRRE---DKKRKWGEGISP 290
Score = 80.1 bits (196), Expect = 7e-15
Identities = 52/243 (21%), Positives = 101/243 (41%), Gaps = 12/243 (4%)
Query: 428 SRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQ 487
SR +++ RS +A + + RD R ++ K RDR R R + R
Sbjct: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKT-EKERDRDRKRDRERRR---- 104
Query: 488 LGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQ 547
KE++ R+R K+ + + R K++ R R +ER+R + R KER+R
Sbjct: 105 -----KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDRE--KERERQT 157
Query: 548 SRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSR 607
+ +RE R +ER++++ R ++R+R++ ER R R +++ R
Sbjct: 158 EKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTER 217
Query: 608 PRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRT 667
R + +E R ++ + + + +E D + ++ + + R
Sbjct: 218 QRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
Query: 668 PSK 670
K
Sbjct: 278 EDK 280
Score = 53.1 bits (126), Expect = 9e-07
Identities = 38/181 (20%), Positives = 63/181 (34%), Gaps = 6/181 (3%)
Query: 261 EMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARS--RT 318
E + K N+ R + + R + + ++R R R R R R +
Sbjct: 101 ERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKD 160
Query: 319 RKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHR 378
R G + R K K + R R R R +R R + ER
Sbjct: 161 RDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRE 220
Query: 379 GSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS 438
+E+ R + +QRD R + ++ RDR R + ++R + R K +
Sbjct: 221 TDREGERETDRRRE----RQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKR 276
Query: 439 R 439
R
Sbjct: 277 R 277
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 15/187 (8%)
Query: 485 HSQLGSPSKE----RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540
HS LG+ E D R R S+E RS + H+ + ++R+R + R
Sbjct: 33 HSSLGTLWVEVTIPLDFSRGRLGSQE----SPRSWGLGQAHKDADGDDRQRERDRVREKT 88
Query: 541 -KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSP 599
KERDR + R R+ +++ R+R R + ER+R + + ER+ R R
Sbjct: 89 EKERDRDRKRDRERRRKEKETN-----RNRDREKQTEIERDREREKQKGRERERDRGRER 143
Query: 600 NKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRT 659
+ + R EK R E + R KE + + R D ++ R
Sbjct: 144 ERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR-DRQRDTEKERERQ 202
Query: 660 SSLSQNR 666
+ ++R
Sbjct: 203 TDRERDR 209
Score = 39.3 bits (90), Expect = 0.013
Identities = 35/172 (20%), Positives = 62/172 (36%), Gaps = 9/172 (5%)
Query: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQK----RTHSRVRSHSWK 308
R++ + R + + R R + + R + R G ++ R R R +
Sbjct: 123 RDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
Query: 309 RNHSRARSRTRKGILSQMGRHSQSRSHS-KGKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367
R R R R R + + + R K +++ Q T R G R +ER
Sbjct: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRR---RERQRDR 239
Query: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSP 419
R ++R+ R RK+ + + K++ R +K R SP
Sbjct: 240 DRGKERDRE-RDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 100 bits (249), Expect = 5e-21
Identities = 59/213 (27%), Positives = 98/213 (46%), Gaps = 7/213 (3%)
Query: 384 RKESGRSQSGSPNKQRDHSRSRSPNKARDR---SRSRSPYKARDRSRSRSPNKARDCSRS 440
+ E + + + R R R ++ RDR S++ + RDR R R N+ RD R
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
Query: 441 RSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRS 500
R K DR R + RD R R + RD+ R E D + +E + R
Sbjct: 64 RE--KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
Query: 501 RSPSKERQCRQSRSSSKERDHRRSRSPSKERQR-RQSRSPNKERDRSQSRSPSEEREHRQ 559
R K+++ + R + +E D R R +ER+ R+ ++ ++ R+R + R ER+ R+
Sbjct: 122 REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK-RE 180
Query: 560 SRSPSKERDRRRWRSPSKERERRQSRSSSEERD 592
++ + D R R +R+R + R S ERD
Sbjct: 181 TKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 98.6 bits (244), Expect = 2e-20
Identities = 62/212 (29%), Positives = 98/212 (46%), Gaps = 13/212 (6%)
Query: 401 HSRSRSPNKARDRSRSRSPYKARDRSR-SRSPNKARDCSRSRSPYKARDRSRSRSPNKAR 459
H+ + + R R R R + RDR++ S++ ++ + R R + R+R R R K
Sbjct: 9 HTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQT 68
Query: 460 DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER 519
D R + RDR R R +ERD KER+ R +ERQ ++ R + R
Sbjct: 69 DREGERQRERERDRDRQRETERERD--------KERETDRHTETDRERQKQKEREMERVR 120
Query: 520 DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHR-QSRSPSKERDRRRWRS---P 575
D R + R+R+ R ++ER+R R RE + + R +ER+R+R R
Sbjct: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
Query: 576 SKERERRQSRSSSEERDHSRSRSPNKQSGYSR 607
+KERER +R+ R R ++S R
Sbjct: 181 TKERERHTDMERERQRETDRKRDRQRESERER 212
Score = 95.1 bits (235), Expect = 2e-19
Identities = 58/213 (27%), Positives = 94/213 (44%), Gaps = 9/213 (4%)
Query: 362 ERSHSHSRSSSKERDH---RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
E H+H+ + + +R R + R + S++ + +RD R R N+ RDR R R
Sbjct: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
Query: 419 PYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRS 478
K DR R + RD R R + RD+ R + D R + + +R R R
Sbjct: 66 --KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
Query: 479 PSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRS 538
K+++ + +E D R R +ER+ + R K D R R ++R+R + R
Sbjct: 124 REKQKEMGRERQTDRETDRERERQAERERETGRER---KTEDRHRERERERKRERERKRE 180
Query: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRRR 571
KER+R +RE + R +E +R R
Sbjct: 181 -TKERERHTDMERERQRETDRKRDRQRESERER 212
Score = 90.5 bits (223), Expect = 5e-18
Identities = 56/215 (26%), Positives = 92/215 (42%), Gaps = 6/215 (2%)
Query: 343 QSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH-RGSSSPRKESGRSQSGSPNKQRDH 401
+S+T R H + + +R R + +ERD + S + + S R + + R+
Sbjct: 2 ESKTEGR---HTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRER 58
Query: 402 SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDH 461
R R K DR R + RDR R R + RD R + DR R + + +
Sbjct: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
Query: 462 SRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDH 521
R R K ++ R R +E D + +ER+ R R +++R + R +ER+
Sbjct: 119 VRDREREKQKEMGRERQTDRETDRERERQAERERETGRERK-TEDRHRERERERKRERER 177
Query: 522 RRSRSPSKERQRRQSRSPNKERDRSQSRSPSEERE 556
+R + +ER R +E DR + R ERE
Sbjct: 178 KR-ETKERERHTDMERERQRETDRKRDRQRESERE 211
Score = 85.1 bits (209), Expect = 2e-16
Identities = 57/215 (26%), Positives = 94/215 (43%), Gaps = 11/215 (5%)
Query: 335 HSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS 394
H+ +++ R R R + R+ +KE S + ERD + +E R +
Sbjct: 9 HTHTETETMDRQRERRRETDRERDRAKE---SKTEDRHSERDRQRDRERNRERDRDRERE 65
Query: 395 PNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRS 454
KQ D R + RDR R R + RD+ R + D R + + +R R R
Sbjct: 66 --KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
Query: 455 PNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRS 514
K ++ R R ++ DR R R +ER + G K D R R ++R+ R+ +
Sbjct: 124 REKQKEMGRERQTDRETDRERERQAERER---ETGRERKTEDRHRERERERKRE-RERKR 179
Query: 515 SSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
+KER+ R +ERQR R +++R+ + R
Sbjct: 180 ETKERE--RHTDMERERQRETDRKRDRQRESERER 212
Score = 82.0 bits (201), Expect = 2e-15
Identities = 49/212 (23%), Positives = 90/212 (42%), Gaps = 11/212 (5%)
Query: 327 GRHSQSRSHSKGKSQNQSRTPRRGR-----SHNWSRNPSKERSHSHSRSSSKERDHRGSS 381
GRH+ + + + + + + R R R S R+ ++R R+ ++RD
Sbjct: 7 GRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREK 66
Query: 382 SPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441
+E R + ++RD R R + RD+ R + DR R + + + R R
Sbjct: 67 QTDREGERQRE----RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
Query: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501
K ++ R R ++ D R R + R+ R R +++R + +ER+ +R
Sbjct: 123 EREKQKEMGRERQTDRETDRERERQAERERETGRERK-TEDRHRERERERKRERERKRE- 180
Query: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQR 533
+ +ER R +E D +R R ER+R
Sbjct: 181 TKERERHTDMERERQRETDRKRDRQRESERER 212
Score = 79.3 bits (194), Expect = 1e-14
Identities = 56/227 (24%), Positives = 92/227 (40%), Gaps = 16/227 (7%)
Query: 295 QKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHN 354
+ +T R +H+ R R R R + R SK + ++ R +R R N
Sbjct: 2 ESKTEGR-HTHTETETMDRQRERRR-----ETDRERDRAKESKTEDRHSERDRQRDRERN 55
Query: 355 WSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS 414
R+ +ER K+ D G +E R + ++RD R + DR
Sbjct: 56 RERDRDRERE--------KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE 107
Query: 415 RSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSR-SPNKARDR 473
R + + +R R R K ++ R R + DR R R + R+ R R + ++ R+R
Sbjct: 108 RQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRER 167
Query: 474 SRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD 520
R R +ER + + D R R +R+ + R S +ERD
Sbjct: 168 ERERKRERERKR-ETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 77.0 bits (188), Expect = 6e-14
Identities = 48/205 (23%), Positives = 86/205 (41%), Gaps = 5/205 (2%)
Query: 494 ERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS---KERQRRQSRSPNKERDRSQSRS 550
E H + + + +RQ + R + +ERD + ER R++ R N+ERDR + R
Sbjct: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
Query: 551 PSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRA 610
+RE + R +ERDR R R +ER++ + E D R + ++ R R
Sbjct: 66 KQTDREGERQRE--RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
Query: 611 SSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSK 670
K+K R R +E + + R + +E + + +R R + R +
Sbjct: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKE 183
Query: 671 TSSHSPSTFPSGGQTLSQDDSQADA 695
H+ +T + D Q ++
Sbjct: 184 RERHTDMERERQRETDRKRDRQRES 208
Score = 71.6 bits (174), Expect = 2e-12
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 1/174 (0%)
Query: 482 ERDHSQLGSPSKERDHRRSRSPSKER-QCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540
E H+ + + +R R R +ER + ++S++ + + R R + R+R + R
Sbjct: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
Query: 541 KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN 600
K+ DR R ER+ + R +ERD+ R E +R + + E + R R
Sbjct: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE 125
Query: 601 KQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKR 654
KQ R R + +E R R +E + R + + R + KR
Sbjct: 126 KQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
Score = 69.7 bits (169), Expect = 9e-12
Identities = 56/235 (23%), Positives = 86/235 (36%), Gaps = 43/235 (18%)
Query: 275 RSRPQSHSQSRSPRRSRSGSQKRTHS-RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSR 333
R R + R R++ + HS R R +RN R R R R
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRER-------------- 64
Query: 334 SHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSG 393
+ +T R G R +ER R + +ERD + E+ R +
Sbjct: 65 ---------EKQTDREG-----ERQRERERDRDRQRETERERDKERETDRHTETDRERQK 110
Query: 394 SPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR 453
++ + R R K ++ R R + DR R R + R+ R R K DR R R
Sbjct: 111 QKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRER---KTEDRHRER 167
Query: 454 SPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508
+ R+ R R + ++R R +ER +E D +R R ER+
Sbjct: 168 ERERKRERERKR---ETKERERHTDMERER--------QRETDRKRDRQRESERE 211
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 13/139 (9%)
Query: 515 SSKERDHRRSRSPSKERQRRQSRSPNKERDR---SQSRSPSEEREHRQSRSPSKERDRRR 571
S E H + + + +RQR + R ++ERDR S++ ER+ ++ R ++ERDR R
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
Query: 572 WRSP----------SKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621
R +ER+R + R + ERD R + ++ R + +E R R
Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
Query: 622 TPSKEGNHSQSRTSSKESD 640
K+ + R + +E+D
Sbjct: 123 EREKQKEMGRERQTDRETD 141
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/235 (21%), Positives = 81/235 (34%), Gaps = 48/235 (20%)
Query: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHS 312
R ++ + + K+ ++ S R R + ++R R R ++ R +R+
Sbjct: 24 RRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRD 83
Query: 313 RARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSS 372
R R R+ +++ R R + R KER R
Sbjct: 84 RQRETERE--------------------RDKERETDRHTETDRERQKQKEREMERVRDRE 123
Query: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
+E KQ++ R R ++ DR R R + R+ R R
Sbjct: 124 RE----------------------KQKEMGRERQTDRETDRERERQAERERETGRER--- 158
Query: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHS---RSRSPNKARDRSRSRSPSKERD 484
K D R R + R+R R R + H+ R R R R R R +ERD
Sbjct: 159 KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.113 0.310
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,781,741
Number of Sequences: 37866
Number of extensions: 1734599
Number of successful extensions: 52838
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 644
Number of HSP's successfully gapped in prelim test: 1432
Number of HSP's that attempted gapping in prelim test: 11458
Number of HSP's gapped (non-prelim): 13121
length of query: 715
length of database: 18,247,518
effective HSP length: 109
effective length of query: 606
effective length of database: 14,120,124
effective search space: 8556795144
effective search space used: 8556795144
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.