Guide to the Human Genome
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Search of human proteins with 224465242

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224465242 BTB (POZ) domain containing 8 [Homo sapiens]
         (378 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224465242 BTB (POZ) domain containing 8 [Homo sapiens]             761   0.0  
gi|25777626 ankyrin repeat and BTB (POZ) domain containing 1 iso...    65   8e-11
gi|25777624 ankyrin repeat and BTB (POZ) domain containing 1 iso...    65   8e-11
gi|57242759 regulator of chromosome condensation (RCC1) and BTB ...    64   3e-10
gi|57863304 inhibitor of Bruton's tyrosine kinase [Homo sapiens]       63   4e-10
gi|48717263 speckle-type POZ protein-like [Homo sapiens]               62   8e-10
gi|209571547 kelch repeat and BTB (POZ) domain containing 4 isof...    59   5e-09
gi|209693446 kelch repeat and BTB (POZ) domain containing 4 isof...    59   7e-09
gi|5174473 intracisternal A particle-promoted polypeptide isofor...    58   2e-08
gi|223890235 intracisternal A particle-promoted polypeptide isof...    58   2e-08
gi|11056006 kelch-like 12 [Homo sapiens]                               58   2e-08
gi|40018614 DRE1 protein [Homo sapiens]                                57   3e-08
gi|55925604 kelch-like 18 [Homo sapiens]                               57   4e-08
gi|24432026 kelch-like [Homo sapiens]                                  55   8e-08
gi|148664209 kelch-like 10 [Homo sapiens]                              55   1e-07
gi|56117834 speckle-type POZ protein [Homo sapiens]                    55   1e-07
gi|56117832 speckle-type POZ protein [Homo sapiens]                    55   1e-07
gi|56117830 speckle-type POZ protein [Homo sapiens]                    55   1e-07
gi|56117828 speckle-type POZ protein [Homo sapiens]                    55   1e-07
gi|4507183 speckle-type POZ protein [Homo sapiens]                     55   1e-07
gi|56117836 speckle-type POZ protein [Homo sapiens]                    55   1e-07
gi|55925608 kelch-like 21 [Homo sapiens]                               54   2e-07
gi|223468659 kelch repeat and BTB (POZ) domain containing 2 [Hom...    54   2e-07
gi|40807500 kelch-like 20 [Homo sapiens]                               53   4e-07
gi|14780904 kelch-like 1 protein [Homo sapiens]                        52   9e-07
gi|156616301 kelch-like 32 [Homo sapiens]                              52   9e-07
gi|14211841 ankyrin repeat and BTB (POZ) domain containing 1 iso...    52   1e-06
gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens]    51   1e-06
gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens]    51   1e-06
gi|44680141 BTB (POZ) domain containing 5 [Homo sapiens]               51   1e-06

>gi|224465242 BTB (POZ) domain containing 8 [Homo sapiens]
          Length = 378

 Score =  761 bits (1965), Expect = 0.0
 Identities = 378/378 (100%), Positives = 378/378 (100%)

Query: 1   MARCGEGSAAPMVLLGSAGVCSKGLQRKGPCERRRLKATVSEQLSQDLLRLLREEFHTDV 60
           MARCGEGSAAPMVLLGSAGVCSKGLQRKGPCERRRLKATVSEQLSQDLLRLLREEFHTDV
Sbjct: 1   MARCGEGSAAPMVLLGSAGVCSKGLQRKGPCERRRLKATVSEQLSQDLLRLLREEFHTDV 60

Query: 61  TFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAVENVEALEFRTFLQIIYS 120
           TFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAVENVEALEFRTFLQIIYS
Sbjct: 61  TFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAVENVEALEFRTFLQIIYS 120

Query: 121 SNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSSDCSLQKHEIPEDISDRDDDFIS 180
           SNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSSDCSLQKHEIPEDISDRDDDFIS
Sbjct: 121 SNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSSDCSLQKHEIPEDISDRDDDFIS 180

Query: 181 NDNYDLEPASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWA 240
           NDNYDLEPASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWA
Sbjct: 181 NDNYDLEPASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWA 240

Query: 241 ESSQEYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIYIL 300
           ESSQEYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIYIL
Sbjct: 241 ESSQEYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIYIL 300

Query: 301 RRDYCNFFQKPVPRTLTSILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANIPP 360
           RRDYCNFFQKPVPRTLTSILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANIPP
Sbjct: 301 RRDYCNFFQKPVPRTLTSILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANIPP 360

Query: 361 EIQKSCLNMLIQSLVSIT 378
           EIQKSCLNMLIQSLVSIT
Sbjct: 361 EIQKSCLNMLIQSLVSIT 378


>gi|25777626 ankyrin repeat and BTB (POZ) domain containing 1
           isoform 3 [Homo sapiens]
          Length = 453

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 76/271 (28%), Positives = 112/271 (41%), Gaps = 31/271 (11%)

Query: 48  LLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAVENVE 107
           L RLL +  H+DV F V    F+ H+ VL AR    YF  +  T     +   +    + 
Sbjct: 80  LQRLLEQGIHSDVVFVVHGKPFRVHRCVLGAR--SAYFANMLDTKWKGKSVVVLRHPLIN 137

Query: 108 ALEFRTFLQIIYSSNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSSDCSLQK--- 164
            + F   LQ +Y+   +I         +   +  +     D+   KCE  S+    K   
Sbjct: 138 PVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLE-AKCEKVSEFVASKPGT 196

Query: 165 -------HEIPEDISDRDDDFISNDNYDLEPASELGEDLLKLYVKPC------CPDIDIF 211
                     P D   R+D  +  D   L P  EL  DL +L   PC      CPDI   
Sbjct: 197 CVKVLTIEPPPADPRLREDMALLAD-CALPP--ELRGDLWELPF-PCPDGFNSCPDICFR 252

Query: 212 VDGKRFKAHRAILSARSSYFAAMLSGCWAESSQ-------EYVTLQGISHVELNVMMHFI 264
           V G  F  H+A    RS YF A+L   + ES +         VTL GIS      +++++
Sbjct: 253 VAGCSFLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYM 312

Query: 265 YGGTLDIPDKTNVGQILNMADMYGLEGLKEV 295
           Y    ++  +     +L++ADMY L GLK +
Sbjct: 313 YSDHTELSPEA-AYDVLSVADMYLLPGLKRL 342


>gi|25777624 ankyrin repeat and BTB (POZ) domain containing 1
           isoform 2 [Homo sapiens]
          Length = 478

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 76/271 (28%), Positives = 112/271 (41%), Gaps = 31/271 (11%)

Query: 48  LLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAVENVE 107
           L RLL +  H+DV F V    F+ H+ VL AR    YF  +  T     +   +    + 
Sbjct: 105 LQRLLEQGIHSDVVFVVHGKPFRVHRCVLGAR--SAYFANMLDTKWKGKSVVVLRHPLIN 162

Query: 108 ALEFRTFLQIIYSSNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSSDCSLQK--- 164
            + F   LQ +Y+   +I         +   +  +     D+   KCE  S+    K   
Sbjct: 163 PVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLE-AKCEKVSEFVASKPGT 221

Query: 165 -------HEIPEDISDRDDDFISNDNYDLEPASELGEDLLKLYVKPC------CPDIDIF 211
                     P D   R+D  +  D   L P  EL  DL +L   PC      CPDI   
Sbjct: 222 CVKVLTIEPPPADPRLREDMALLAD-CALPP--ELRGDLWELPF-PCPDGFNSCPDICFR 277

Query: 212 VDGKRFKAHRAILSARSSYFAAMLSGCWAESSQ-------EYVTLQGISHVELNVMMHFI 264
           V G  F  H+A    RS YF A+L   + ES +         VTL GIS      +++++
Sbjct: 278 VAGCSFLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYM 337

Query: 265 YGGTLDIPDKTNVGQILNMADMYGLEGLKEV 295
           Y    ++  +     +L++ADMY L GLK +
Sbjct: 338 YSDHTELSPEA-AYDVLSVADMYLLPGLKRL 367


>gi|57242759 regulator of chromosome condensation (RCC1) and BTB
           (POZ) domain containing protein 1 [Homo sapiens]
          Length = 531

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 40/165 (24%), Positives = 71/165 (43%), Gaps = 17/165 (10%)

Query: 192 LGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQG 251
           + E L K +  P   D+   +DGK    H+A+L  R  +F +M    W E  +E + +  
Sbjct: 356 VAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQ 415

Query: 252 ISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKP 311
            S+      + ++Y  T+D+P +  +G +L++A  Y    LK++  +I++R         
Sbjct: 416 FSYPVYRAFLQYLYTDTVDLPPEDAIG-LLDLATSYCENRLKKLCQHIIKRGI------- 467

Query: 312 VPRTLTSILECLIIAHSVGVESLFADCMKWIVKHF------ARFW 350
              T+ +       A     E L   C K+ + H       A FW
Sbjct: 468 ---TVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFW 509


>gi|57863304 inhibitor of Bruton's tyrosine kinase [Homo sapiens]
          Length = 1353

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 92/385 (23%), Positives = 139/385 (36%), Gaps = 77/385 (20%)

Query: 36  LKATVSEQLSQDLLRLLREEFHTD----VTFSVGCTLFKAHKAVLLARVPDFY------- 84
           + A  S    ++  +LLRE    D    VTF VG  LF AHK +L     DF+       
Sbjct: 538 IPAVSSSSFFEEFGKLLREADEMDSIHDVTFQVGNRLFPAHKYILAVH-SDFFQKLFLSD 596

Query: 85  -----FHTIGQTSNSLTNQEPIAVENVEALEFRTFLQIIY-------------------- 119
                F  I Q            VE V    F   LQ IY                    
Sbjct: 597 GNTSEFTDIYQKDEDSAGCHLFVVEKVHPDMFEYLLQFIYTDTCDFLTHGFKPRIHLNKN 656

Query: 120 --------SSNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSSDCSLQKHEIPED- 170
                   +S+ N  N+ E+  +K   E+  S +   +S  +      C   K+   +D 
Sbjct: 657 PEEYQGTLNSHLNKVNFHEDDNQKSAFEVYKSNQAQTVSERQKSKPKSCKKGKNIREDDP 716

Query: 171 ------ISDRDD--------DFISNDNYDLEPASELGEDLLKLYVKPCCPDIDI---FVD 213
                 ++ + D        D +  +N  +   ++   + LKL  K C    D+    VD
Sbjct: 717 VRMLQTVAKKFDFSNLSSRLDGVRFENEKINVIAKNTGNKLKLSQKKCSFLCDVTMKSVD 776

Query: 214 GKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIY-GGTLDIP 272
           GK F  H+ +L AR  YF +MLS  W E+S        I    L V++ ++Y    + I 
Sbjct: 777 GKEFPCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIHSDILKVILDYLYTDEAVVIK 836

Query: 273 DKTNVG---QILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVPRTLTSILECLIIAHSV 329
           +  NV     +L +AD   +  LKE+    L              TL +    L  A   
Sbjct: 837 ESQNVDFICSVLVVADQLLITRLKEICEVALTEKL----------TLKNAAMLLEFAAMY 886

Query: 330 GVESLFADCMKWIVKHFARFWSERS 354
             + L   C+++I  + A     RS
Sbjct: 887 SAKQLKLSCLQFIGLNMAALLEARS 911


>gi|48717263 speckle-type POZ protein-like [Homo sapiens]
          Length = 392

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 42/114 (36%), Positives = 53/114 (46%), Gaps = 1/114 (0%)

Query: 180 SNDNYDLEPASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCW 239
           +N N    P   L EDL  L+      D   FV G+ FKAH+++L+ARS  F AM     
Sbjct: 174 TNTNTLKVPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEM 233

Query: 240 AESSQEYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLK 293
            ES +  V +  +       MM FIY G     DK     +L  AD Y LE LK
Sbjct: 234 EESKKNRVEINDLDPEVFKEMMRFIYTGRAPNLDKM-ADNLLAAADKYALERLK 286



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 2/78 (2%)

Query: 43  QLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIA 102
           +L++DL  L      TD +F V    FKAHK+VL AR P   F+ + +     + +  + 
Sbjct: 185 RLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSP--VFNAMFEHEMEESKKNRVE 242

Query: 103 VENVEALEFRTFLQIIYS 120
           + +++   F+  ++ IY+
Sbjct: 243 INDLDPEVFKEMMRFIYT 260


>gi|209571547 kelch repeat and BTB (POZ) domain containing 4 isoform
           a [Homo sapiens]
          Length = 534

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 39/144 (27%), Positives = 75/144 (52%), Gaps = 4/144 (2%)

Query: 162 LQKHEIPEDI-SDRDDDFISNDNY-DLEPASELGEDLLKLYVKP-CCPDIDIFVDGKRFK 218
           L   E PE+  +  D+++  N  + D   +  + + ++KL ++     D+ I V+G+ F+
Sbjct: 14  LASMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQ 73

Query: 219 AHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVG 278
            HR +LSA+S +F +M +    E+    + LQ +S     +++ +IY GT+ +  +  + 
Sbjct: 74  LHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAE-ELQ 132

Query: 279 QILNMADMYGLEGLKEVAIYILRR 302
           +I  ++DMY L  L E     L R
Sbjct: 133 EIYEVSDMYQLTSLFEECSRFLAR 156


>gi|209693446 kelch repeat and BTB (POZ) domain containing 4 isoform
           b [Homo sapiens]
          Length = 518

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 38/140 (27%), Positives = 74/140 (52%), Gaps = 4/140 (2%)

Query: 166 EIPEDI-SDRDDDFISNDNY-DLEPASELGEDLLKLYVKP-CCPDIDIFVDGKRFKAHRA 222
           E PE+  +  D+++  N  + D   +  + + ++KL ++     D+ I V+G+ F+ HR 
Sbjct: 2   ESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRL 61

Query: 223 ILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILN 282
           +LSA+S +F +M +    E+    + LQ +S     +++ +IY GT+ +  +  + +I  
Sbjct: 62  VLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAE-ELQEIYE 120

Query: 283 MADMYGLEGLKEVAIYILRR 302
           ++DMY L  L E     L R
Sbjct: 121 VSDMYQLTSLFEECSRFLAR 140


>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
           [Homo sapiens]
          Length = 584

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)

Query: 207 DIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYG 266
           D+ + V  + FKAHR +L+A S YFAA+ +G   ESS++ V + GI      +++ FIY 
Sbjct: 38  DVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDVVPILGIEAGIFQILLDFIYT 97

Query: 267 GTLDIPDKTNVGQILNMADMYGL 289
           G ++I    NV +++  ADM  L
Sbjct: 98  GIVNI-GVNNVQELIIAADMLQL 119


>gi|223890235 intracisternal A particle-promoted polypeptide isoform
           2 [Homo sapiens]
          Length = 582

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)

Query: 207 DIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYG 266
           D+ + V  + FKAHR +L+A S YFAA+ +G   ESS++ V + GI      +++ FIY 
Sbjct: 38  DVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDVVPILGIEAGIFQILLDFIYT 97

Query: 267 GTLDIPDKTNVGQILNMADMYGL 289
           G ++I    NV +++  ADM  L
Sbjct: 98  GIVNI-GVNNVQELIIAADMLQL 119


>gi|11056006 kelch-like 12 [Homo sapiens]
          Length = 568

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 30/94 (31%), Positives = 55/94 (58%), Gaps = 1/94 (1%)

Query: 207 DIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYG 266
           D+ + V+ K F AHR +L+A S YF AM +   +E  + YV +QG++   + +++ F+Y 
Sbjct: 34  DVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDFVYT 93

Query: 267 GTLDIPDKTNVGQILNMADMYGLEGLKEVAIYIL 300
            T+ +  + NV ++L  A +  L+G+K+     L
Sbjct: 94  ETVHVTVE-NVQELLPAACLLQLKGVKQACCEFL 126


>gi|40018614 DRE1 protein [Homo sapiens]
          Length = 600

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 42/157 (26%), Positives = 71/157 (45%), Gaps = 20/157 (12%)

Query: 169 EDISDRDDDFISNDNYDLEPASELG-------------EDLLKLYVK----PCCPDIDIF 211
           ED+  RD        ++++P S  G             E++L+++ +        D+ I 
Sbjct: 12  EDLGVRDSPATKRKVFEMDPKSLTGHEFFDFSSGSSHAENILQIFNEFRDSRLFTDVIIC 71

Query: 212 VDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYGGTLDI 271
           V+GK F  HRA+LSA SSYF AM      ES +  V + GI    +   + ++Y G + I
Sbjct: 72  VEGKEFPCHRAVLSACSSYFRAMFCNDHRESREMLVEINGILAEAMECFLQYVYTGKVKI 131

Query: 272 PDKTNVGQILNMADMYGLEGLKEVAIYILRR--DYCN 306
             + NV  +   + ++ +  L++     L    D CN
Sbjct: 132 TTE-NVQYLFETSSLFQISVLRDACAKFLEEQLDPCN 167


>gi|55925604 kelch-like 18 [Homo sapiens]
          Length = 574

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 39/155 (25%), Positives = 69/155 (44%), Gaps = 11/155 (7%)

Query: 207 DIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYG 266
           D+ + +   +F AHR +L+A   YF AM +    E  Q+ + +QG+    L  +++F Y 
Sbjct: 39  DVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYN 98

Query: 267 GTLDIPDKTNVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVPRTLTSILECLIIA 326
           G L I D+ NV  +L  A    L+ +K+     LR       ++  P+    + +    A
Sbjct: 99  GNLAI-DQQNVQSLLMGASFLQLQSIKDACCTFLR-------ERLHPKNCLGVRQ---FA 147

Query: 327 HSVGVESLFADCMKWIVKHFARFWSERSFANIPPE 361
            ++    L+     +I +HF        F  +P E
Sbjct: 148 ETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPLE 182



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 2/64 (3%)

Query: 59  DVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAVENVEALEFRTFLQII 118
           DVT  +G   F AH+ VL A +P  YFH +         Q+ I ++ ++       +   
Sbjct: 39  DVTLKIGDHKFSAHRIVLAASIP--YFHAMFTNDMMECKQDEIVMQGMDPSALEALINFA 96

Query: 119 YSSN 122
           Y+ N
Sbjct: 97  YNGN 100


>gi|24432026 kelch-like [Homo sapiens]
          Length = 634

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 48/190 (25%), Positives = 84/190 (44%), Gaps = 11/190 (5%)

Query: 179 ISNDNYDLEPASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGC 238
           ++N     + +  L   LL L       D+ + V+G+  +AHR +L+A   YF  M +G 
Sbjct: 23  VNNTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGRHIEAHRILLAASCDYFRGMFAGG 82

Query: 239 WAESSQEYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIY 298
             E  QE V + G+S+  +  ++HFIY   L++   +NV + L  A         ++ I 
Sbjct: 83  LKEMEQEEVLIHGVSYNAMCQILHFIYTSELEL-SLSNVQETLVAA--------CQLQIP 133

Query: 299 ILRRDYCNFFQKPVPRTLTSILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANI 358
            +    C+F    V     +IL+   +A    +  L      +I+K+F  F     +  +
Sbjct: 134 EIIHFCCDFLMSWVDE--ENILDVYRLAELFDLSRLTEQLDTYILKNFVAFSRTDKYRQL 191

Query: 359 PPEIQKSCLN 368
           P E   S L+
Sbjct: 192 PLEKVYSLLS 201


>gi|148664209 kelch-like 10 [Homo sapiens]
          Length = 608

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 5/110 (4%)

Query: 197 LKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVE 256
           L+L  K C  D+ I V+G  F AH+ IL + SSYF A+ +  W  + ++   + GIS   
Sbjct: 32  LRLEGKLC--DVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDM 89

Query: 257 LNVMMHFIYGGTLDI-PDKTNVGQILNMADMYGLEGLKEVAIYILRRDYC 305
           + +++ + Y  T+ I PD  NV ++L  AD + + G+       L+ + C
Sbjct: 90  MKLIIEYAYTRTVPITPD--NVEKLLAAADQFNIMGIVRGCCEFLKSELC 137


>gi|56117834 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/106 (35%), Positives = 51/106 (48%), Gaps = 1/106 (0%)

Query: 188 PASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYV 247
           P   L ++L  L+      D  + V G+ F+AH+AIL+ARS  F+AM      ES +  V
Sbjct: 182 PECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRV 241

Query: 248 TLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLK 293
            +  +       MM FIY G     DK     +L  AD Y LE LK
Sbjct: 242 EINDVEPEVFKEMMCFIYTGKAPNLDKM-ADDLLAAADKYALERLK 286



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 43  QLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIA 102
           +L+ +L  L      TD    V    F+AHKA+L AR P F      +   S  N+  + 
Sbjct: 185 RLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR--VE 242

Query: 103 VENVEALEFRTFLQIIYSSNR-NIKNYEEEIL 133
           + +VE   F+  +  IY+    N+    +++L
Sbjct: 243 INDVEPEVFKEMMCFIYTGKAPNLDKMADDLL 274


>gi|56117832 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/106 (35%), Positives = 51/106 (48%), Gaps = 1/106 (0%)

Query: 188 PASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYV 247
           P   L ++L  L+      D  + V G+ F+AH+AIL+ARS  F+AM      ES +  V
Sbjct: 182 PECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRV 241

Query: 248 TLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLK 293
            +  +       MM FIY G     DK     +L  AD Y LE LK
Sbjct: 242 EINDVEPEVFKEMMCFIYTGKAPNLDKM-ADDLLAAADKYALERLK 286



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 43  QLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIA 102
           +L+ +L  L      TD    V    F+AHKA+L AR P F      +   S  N+  + 
Sbjct: 185 RLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR--VE 242

Query: 103 VENVEALEFRTFLQIIYSSNR-NIKNYEEEIL 133
           + +VE   F+  +  IY+    N+    +++L
Sbjct: 243 INDVEPEVFKEMMCFIYTGKAPNLDKMADDLL 274


>gi|56117830 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/106 (35%), Positives = 51/106 (48%), Gaps = 1/106 (0%)

Query: 188 PASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYV 247
           P   L ++L  L+      D  + V G+ F+AH+AIL+ARS  F+AM      ES +  V
Sbjct: 182 PECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRV 241

Query: 248 TLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLK 293
            +  +       MM FIY G     DK     +L  AD Y LE LK
Sbjct: 242 EINDVEPEVFKEMMCFIYTGKAPNLDKM-ADDLLAAADKYALERLK 286



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 43  QLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIA 102
           +L+ +L  L      TD    V    F+AHKA+L AR P F      +   S  N+  + 
Sbjct: 185 RLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR--VE 242

Query: 103 VENVEALEFRTFLQIIYSSNR-NIKNYEEEIL 133
           + +VE   F+  +  IY+    N+    +++L
Sbjct: 243 INDVEPEVFKEMMCFIYTGKAPNLDKMADDLL 274


>gi|56117828 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/106 (35%), Positives = 51/106 (48%), Gaps = 1/106 (0%)

Query: 188 PASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYV 247
           P   L ++L  L+      D  + V G+ F+AH+AIL+ARS  F+AM      ES +  V
Sbjct: 182 PECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRV 241

Query: 248 TLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLK 293
            +  +       MM FIY G     DK     +L  AD Y LE LK
Sbjct: 242 EINDVEPEVFKEMMCFIYTGKAPNLDKM-ADDLLAAADKYALERLK 286



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 43  QLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIA 102
           +L+ +L  L      TD    V    F+AHKA+L AR P F      +   S  N+  + 
Sbjct: 185 RLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR--VE 242

Query: 103 VENVEALEFRTFLQIIYSSNR-NIKNYEEEIL 133
           + +VE   F+  +  IY+    N+    +++L
Sbjct: 243 INDVEPEVFKEMMCFIYTGKAPNLDKMADDLL 274


>gi|4507183 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/106 (35%), Positives = 51/106 (48%), Gaps = 1/106 (0%)

Query: 188 PASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYV 247
           P   L ++L  L+      D  + V G+ F+AH+AIL+ARS  F+AM      ES +  V
Sbjct: 182 PECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRV 241

Query: 248 TLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLK 293
            +  +       MM FIY G     DK     +L  AD Y LE LK
Sbjct: 242 EINDVEPEVFKEMMCFIYTGKAPNLDKM-ADDLLAAADKYALERLK 286



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 43  QLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIA 102
           +L+ +L  L      TD    V    F+AHKA+L AR P F      +   S  N+  + 
Sbjct: 185 RLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR--VE 242

Query: 103 VENVEALEFRTFLQIIYSSNR-NIKNYEEEIL 133
           + +VE   F+  +  IY+    N+    +++L
Sbjct: 243 INDVEPEVFKEMMCFIYTGKAPNLDKMADDLL 274


>gi|56117836 speckle-type POZ protein [Homo sapiens]
          Length = 374

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/106 (35%), Positives = 51/106 (48%), Gaps = 1/106 (0%)

Query: 188 PASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYV 247
           P   L ++L  L+      D  + V G+ F+AH+AIL+ARS  F+AM      ES +  V
Sbjct: 182 PECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRV 241

Query: 248 TLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLK 293
            +  +       MM FIY G     DK     +L  AD Y LE LK
Sbjct: 242 EINDVEPEVFKEMMCFIYTGKAPNLDKM-ADDLLAAADKYALERLK 286



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 3/92 (3%)

Query: 43  QLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIA 102
           +L+ +L  L      TD    V    F+AHKA+L AR P F      +   S  N+  + 
Sbjct: 185 RLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR--VE 242

Query: 103 VENVEALEFRTFLQIIYSSNR-NIKNYEEEIL 133
           + +VE   F+  +  IY+    N+    +++L
Sbjct: 243 INDVEPEVFKEMMCFIYTGKAPNLDKMADDLL 274


>gi|55925608 kelch-like 21 [Homo sapiens]
          Length = 597

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 11/140 (7%)

Query: 214 GKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYGGTLDIPD 273
           G+ F AHRA+L+A S YF AM +G   ES  E V L G+    L +++ F Y G + +  
Sbjct: 44  GRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAV-S 102

Query: 274 KTNVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVPRTLTSILECLIIAHSVGVES 333
             N   +L  AD+     +KE     L++             L + L+    A +     
Sbjct: 103 GDNAEPLLRAADLLQFPAVKEACGAFLQQQL----------DLANCLDMQDFAEAFSCSG 152

Query: 334 LFADCMKWIVKHFARFWSER 353
           L +   ++I++H     +E+
Sbjct: 153 LASAAQRFILRHVGELGAEQ 172


>gi|223468659 kelch repeat and BTB (POZ) domain containing 2 [Homo
           sapiens]
          Length = 623

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 2/117 (1%)

Query: 187 EPASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEY 246
           E A  L E L   Y +    DI + V+G  F  H+ +L+  SSYF AM     +ES Q +
Sbjct: 12  EYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTH 71

Query: 247 VTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEG-LKEVAIYILRR 302
           V L+ +    L +++ + Y G L + D T V Q+   A    +E  L+    Y++++
Sbjct: 72  VHLRNVDAATLQIIITYAYTGNLAMNDST-VEQLYETACFLQVEDVLQRCREYLIKK 127



 Score = 33.1 bits (74), Expect = 0.42
 Identities = 21/91 (23%), Positives = 38/91 (41%), Gaps = 2/91 (2%)

Query: 32  ERRRLKATVSEQLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQT 91
           + R++    +  L + L     ++  TD+   V  T F  HK VL       YF  +  +
Sbjct: 5   DERQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVL--ATCSSYFRAMFMS 62

Query: 92  SNSLTNQEPIAVENVEALEFRTFLQIIYSSN 122
             S + Q  + + NV+A   +  +   Y+ N
Sbjct: 63  GLSESKQTHVHLRNVDAATLQIIITYAYTGN 93


>gi|40807500 kelch-like 20 [Homo sapiens]
          Length = 609

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 35/108 (32%), Positives = 58/108 (53%), Gaps = 3/108 (2%)

Query: 195 DLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISH 254
           +LL+ + + C  D+ + V  K+  AHR ILSA S YF AM +G  AES Q  V ++ I  
Sbjct: 59  NLLRKHRELC--DVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESRQTEVVIRDIDE 116

Query: 255 VELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIYILRR 302
             + +++ F Y   + + ++ NV  +L  A +  L  ++E     L+R
Sbjct: 117 RAMELLIDFAYTSQITV-EEGNVQTLLPAACLLQLAEIQEACCEFLKR 163


>gi|14780904 kelch-like 1 protein [Homo sapiens]
          Length = 748

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 1/96 (1%)

Query: 207 DIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYG 266
           D+ + V  ++  AHR +LS+ S YFAAM +    E+ QE + ++GI    L  ++ F Y 
Sbjct: 213 DVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAKQEEIKMEGIDPNALWDLVQFAYT 272

Query: 267 GTLDIPDKTNVGQILNMADMYGLEGLKEVAIYILRR 302
           G L++ + T +  +L  A +  L  + EV  + L +
Sbjct: 273 GCLELKEDT-IENLLAAACLLQLPQVVEVCCHFLMK 307


>gi|156616301 kelch-like 32 [Homo sapiens]
          Length = 620

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 24/63 (38%), Positives = 37/63 (58%)

Query: 207 DIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYG 266
           DI +  + ++F AH+A+L+A S YF AM S C  ES  + V L G++ + L   + F Y 
Sbjct: 43  DITLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYT 102

Query: 267 GTL 269
           G +
Sbjct: 103 GQI 105


>gi|14211841 ankyrin repeat and BTB (POZ) domain containing 1
           isoform 1 [Homo sapiens]
          Length = 336

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 40/118 (33%), Positives = 57/118 (48%), Gaps = 15/118 (12%)

Query: 191 ELGEDLLKLYVKPC------CPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQ 244
           EL  DL +L   PC      CPDI   V G  F  H+A    RS YF A+L   + ES +
Sbjct: 110 ELRGDLWELPF-PCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRALLDDHFRESEE 168

Query: 245 -------EYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEV 295
                    VTL GIS      +++++Y    ++  +     +L++ADMY L GLK +
Sbjct: 169 PATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEA-AYDVLSVADMYLLPGLKRL 225


>gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens]
          Length = 612

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 3/91 (3%)

Query: 207 DIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQE-YVTLQGISHVELNVMMHFIY 265
           D+   V+ KRF AHR IL+AR  YF A+L G   ES  E  + LQ  +     +++ +IY
Sbjct: 37  DVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIY 96

Query: 266 GGTLDIPDKTN--VGQILNMADMYGLEGLKE 294
            G   + D+    +   L++A  YG   L++
Sbjct: 97  TGRATLTDEKEEVLLDFLSLAHKYGFPELED 127



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 44  LSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAV 103
           LS+ +  LL  E + DVTF V    F AH+ +L AR   F     G    S    E I +
Sbjct: 22  LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAE-IPL 80

Query: 104 ENVEALEFRTFLQIIYSSNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSS 158
           ++  A  F   L+ IY+    + + +EE+L   +  + ++ K     FP+ E+S+
Sbjct: 81  QDTTAEAFTMLLKYIYTGRATLTDEKEEVL---LDFLSLAHK---YGFPELEDST 129


>gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens]
          Length = 612

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 3/91 (3%)

Query: 207 DIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQE-YVTLQGISHVELNVMMHFIY 265
           D+   V+ KRF AHR IL+AR  YF A+L G   ES  E  + LQ  +     +++ +IY
Sbjct: 37  DVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIY 96

Query: 266 GGTLDIPDKTN--VGQILNMADMYGLEGLKE 294
            G   + D+    +   L++A  YG   L++
Sbjct: 97  TGRATLTDEKEEVLLDFLSLAHKYGFPELED 127



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 44  LSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAV 103
           LS+ +  LL  E + DVTF V    F AH+ +L AR   F     G    S    E I +
Sbjct: 22  LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAE-IPL 80

Query: 104 ENVEALEFRTFLQIIYSSNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSS 158
           ++  A  F   L+ IY+    + + +EE+L   +  + ++ K     FP+ E+S+
Sbjct: 81  QDTTAEAFTMLLKYIYTGRATLTDEKEEVL---LDFLSLAHK---YGFPELEDST 129


>gi|44680141 BTB (POZ) domain containing 5 [Homo sapiens]
          Length = 571

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 46/189 (24%), Positives = 82/189 (43%), Gaps = 20/189 (10%)

Query: 193 GEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGI 252
           G +LL+ + + C  DI + V   +  AH+ +L++ S YF AM +G  +E     V  Q I
Sbjct: 24  GLNLLRQHHELC--DIILRVGDVKIHAHKVVLASVSPYFKAMFTGNLSEKENSEVEFQCI 81

Query: 253 SHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPV 312
               L  ++ + Y GT+ I   T V  +L  A++        + I ++ ++ C F +  +
Sbjct: 82  DETALQAIVEYAYTGTVFISQDT-VESLLPAANL--------LQIKLVLKECCAFLESQL 132

Query: 313 -PRTLTSILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSF-----ANIPPEIQKSC 366
            P     I      A + G   L+    K+I ++F        F     A++   +   C
Sbjct: 133 DPGNCIGISR---FAETYGCRDLYLAATKYICQNFEAVCQTEEFFELTHADLDEIVSNDC 189

Query: 367 LNMLIQSLV 375
           LN+  +  V
Sbjct: 190 LNVATEETV 198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,311,973
Number of Sequences: 37866
Number of extensions: 542804
Number of successful extensions: 1540
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1309
Number of HSP's gapped (non-prelim): 236
length of query: 378
length of database: 18,247,518
effective HSP length: 104
effective length of query: 274
effective length of database: 14,309,454
effective search space: 3920790396
effective search space used: 3920790396
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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