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Search of human proteins with 223890203
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223890203 zinc finger and BTB domain containing 22 [Homo
sapiens]
(634 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223890203 zinc finger and BTB domain containing 22 [Homo sapi... 1299 0.0
gi|223890199 zinc finger and BTB domain containing 22 [Homo sapi... 1299 0.0
gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens] 233 4e-61
gi|209413766 zinc finger and BTB domain containing 43 [Homo sapi... 182 6e-46
gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens] 182 6e-46
gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens] 152 9e-37
gi|149944640 zinc finger and BTB domain containing 34 [Homo sapi... 133 6e-31
gi|170650685 zinc finger and BTB domain containing 37 isoform a ... 126 5e-29
gi|14210530 zinc finger and BTB domain containing 37 isoform b [... 126 5e-29
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens] 124 3e-28
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens] 124 3e-28
gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi... 106 7e-23
gi|16418383 transcriptional repressor NAC1 [Homo sapiens] 99 2e-20
gi|21389533 BTB (POZ) domain containing 14A [Homo sapiens] 98 2e-20
gi|66932932 promyelocytic leukemia zinc finger protein [Homo sap... 98 3e-20
gi|21359888 promyelocytic leukemia zinc finger protein [Homo sap... 98 3e-20
gi|52694665 zinc finger and BTB domain containing 20 [Homo sapiens] 96 8e-20
gi|46358366 zinc finger protein 746 [Homo sapiens] 95 2e-19
gi|32469509 zinc finger and BTB domain containing 12 [Homo sapiens] 94 4e-19
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo... 92 2e-18
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo... 92 2e-18
gi|153791350 replication initiator 1 isoform 1 [Homo sapiens] 87 4e-17
gi|153792539 replication initiator 1 isoform 1 [Homo sapiens] 87 4e-17
gi|153792647 replication initiator 1 isoform 3 [Homo sapiens] 87 4e-17
gi|153791994 replication initiator 1 isoform 1 [Homo sapiens] 87 4e-17
gi|5730122 zinc finger and BTB domain containing 6 [Homo sapiens] 86 1e-16
gi|55925466 zinc finger protein 599 [Homo sapiens] 84 5e-16
gi|38348236 zinc finger protein 497 [Homo sapiens] 83 7e-16
gi|33859678 zinc finger protein 416 [Homo sapiens] 82 1e-15
gi|13376460 zinc finger protein 556 [Homo sapiens] 82 1e-15
>gi|223890203 zinc finger and BTB domain containing 22 [Homo
sapiens]
Length = 634
Score = 1299 bits (3361), Expect = 0.0
Identities = 634/634 (100%), Positives = 634/634 (100%)
Query: 1 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS 60
MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
Sbjct: 1 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS 60
Query: 61 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA 120
IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
Sbjct: 61 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA 120
Query: 121 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT 180
AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
Sbjct: 121 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT 180
Query: 181 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP 240
VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP
Sbjct: 181 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP 240
Query: 241 VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV 300
VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV
Sbjct: 241 VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV 300
Query: 301 KRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD 360
KRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD
Sbjct: 301 KRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD 360
Query: 361 VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD 420
VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD
Sbjct: 361 VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD 420
Query: 421 MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG 480
MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG
Sbjct: 421 MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG 480
Query: 481 DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP
Sbjct: 481 DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
Query: 541 YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG 600
YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG
Sbjct: 541 YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG 600
Query: 601 DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN 634
DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
Sbjct: 601 DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN 634
>gi|223890199 zinc finger and BTB domain containing 22 [Homo
sapiens]
Length = 634
Score = 1299 bits (3361), Expect = 0.0
Identities = 634/634 (100%), Positives = 634/634 (100%)
Query: 1 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS 60
MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
Sbjct: 1 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS 60
Query: 61 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA 120
IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
Sbjct: 61 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA 120
Query: 121 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT 180
AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT
Sbjct: 121 AADIVNFLTVGSVLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGT 180
Query: 181 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP 240
VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP
Sbjct: 181 VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGP 240
Query: 241 VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV 300
VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV
Sbjct: 241 VFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYV 300
Query: 301 KRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD 360
KRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD
Sbjct: 301 KRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISD 360
Query: 361 VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD 420
VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD
Sbjct: 361 VRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLD 420
Query: 421 MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG 480
MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG
Sbjct: 421 MQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSG 480
Query: 481 DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP
Sbjct: 481 DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
Query: 541 YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG 600
YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG
Sbjct: 541 YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSG 600
Query: 601 DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN 634
DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN
Sbjct: 601 DEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN 634
>gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens]
Length = 473
Score = 233 bits (594), Expect = 4e-61
Identities = 194/567 (34%), Positives = 256/567 (45%), Gaps = 125/567 (22%)
Query: 14 PLPLSLAPP-PLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHR 72
P PL P P PA + + FP+ +S+LLESLN+ RL+G+ CDVS+ VQGRE RAH+
Sbjct: 4 PTPLPPVPASPTCNPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHK 63
Query: 73 AVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGS 132
AVLAA+SPYFHD++LL ++LPSV++ AFE +L Y+GRL + + L V S
Sbjct: 64 AVLAAASPYFHDKLLLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVAS 123
Query: 133 VLQMWHIVDKCTELLREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSH 192
LQMW +VD+C+E+LRE S G G+ S GG A + + S
Sbjct: 124 GLQMWQVVDQCSEILRELETS----------------GGGI-SARGGNSYHALLSTTSST 166
Query: 193 AS--SRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSG 250
R+S Q+P S+ +S+ A S VG GE G V V
Sbjct: 167 GGWCIRSSPFQTPVQSS----------ASTESPASTESPVG-GEGSELGEVLQIQVEE-- 213
Query: 251 GATSGKLLLEADELCDDGGDGRGAV----------VPGAGLR--RPTYTPPSIMPQKHWV 298
E +E DD + +G+ V G R P P + P+K
Sbjct: 214 ---------EEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPMTATPRK--- 261
Query: 299 YVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSI 358
+ G + P P P P ++E + EE+ GS P GG E T
Sbjct: 262 -LPEGESAPLELPAPPALPPKIFYIKQEPF------EPKEEISGSGTQP-GGAKEETKVF 313
Query: 359 SDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSG-GPTPSSYAPSHPPRPLL 417
S G EG G + L SG GPT PS
Sbjct: 314 SG------------------------GDTEGNGELGFLLPSGPGPTSGGGGPSWK----- 344
Query: 418 PLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGT 477
P+D+ GN+IL S PG QA HG V +GGT P
Sbjct: 345 PVDLHGNEIL--------SGGGGPG--GAGQAVHGPVKLGGT--------------PPAD 380
Query: 478 GSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTG 537
G K F C CGK F+ K RDRH+ + +LRPF C +CNK+FK+KHHLTEHMKTH G
Sbjct: 381 G-----KRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAG 435
Query: 538 LKPYECGVCAKKFMWRDSFMRHRGHCE 564
+ C C ++F F+RHR C+
Sbjct: 436 AL-HACPHCGRRFRVHACFLRHRDLCK 461
>gi|209413766 zinc finger and BTB domain containing 43 [Homo
sapiens]
Length = 467
Score = 182 bits (463), Expect = 6e-46
Identities = 159/549 (28%), Positives = 224/549 (40%), Gaps = 105/549 (19%)
Query: 27 PAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQV 86
P V FP+ +S +L+ LNQQR QGQLCDVSI VQG FRAH+AVLAASSPYF DQV
Sbjct: 3 PGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQV 62
Query: 87 LLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTEL 146
LLK I LP VM+P FE +L S+YTGRL M A +IV++LT S LQMWH+VDKCTE+
Sbjct: 63 LLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEV 122
Query: 147 LREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSSS 206
L EG P + +H S++QSPSSS
Sbjct: 123 L-EGN-------------------------------PTVLCQKLNH----GSDHQSPSSS 146
Query: 207 NYFSPRESTDFSSSSQEAF-AASAVGSGERRG-------GGPVFPAPVVGSGGATSGKLL 258
+Y ES + S F A + GE + + S +T L
Sbjct: 147 SYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQLTEHEYLPSNSSTEHDRL 206
Query: 259 LEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQDPD 318
+ E+ G+ + RP Y+ PSIM K W++VK P + D
Sbjct: 207 --STEMASQDGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVK-----PERLEQACEGMD 259
Query: 319 LEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPDKGEEQVNFC 378
+ +E + + + E S G E I + + +E ++ +E N+
Sbjct: 260 VHATYDEHQVTESINTVQTEHTVQPS------GVEEDFHIGEKKVEAEFDEQADES-NYD 312
Query: 379 ESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSS 438
E + +G + +++ G H L N +V +S
Sbjct: 313 EQVDFYG--------SSMEEFSGERSDGNLIGHRQEAALAAGYSENIEMVTGIKEEASHL 364
Query: 439 QAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLCHCGKAFSHKS 498
+ G + S + +G P G G CGK F K
Sbjct: 365 GFSATDKLYPCQCGK-SFTHKSQRDRHMSMHLGLRPYGCGV----------CGKKFKMKH 413
Query: 499 MRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMR 558
H+ +H ++P++C +C AK+FMWRDSF R
Sbjct: 414 HLVGHMKIHTGIKPYECNIC----------------------------AKRFMWRDSFHR 445
Query: 559 HRGHCERRH 567
H C + +
Sbjct: 446 HVTSCTKSY 454
>gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]
Length = 467
Score = 182 bits (463), Expect = 6e-46
Identities = 159/549 (28%), Positives = 224/549 (40%), Gaps = 105/549 (19%)
Query: 27 PAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQV 86
P V FP+ +S +L+ LNQQR QGQLCDVSI VQG FRAH+AVLAASSPYF DQV
Sbjct: 3 PGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQV 62
Query: 87 LLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTEL 146
LLK I LP VM+P FE +L S+YTGRL M A +IV++LT S LQMWH+VDKCTE+
Sbjct: 63 LLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEV 122
Query: 147 LREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSSS 206
L EG P + +H S++QSPSSS
Sbjct: 123 L-EGN-------------------------------PTVLCQKLNH----GSDHQSPSSS 146
Query: 207 NYFSPRESTDFSSSSQEAF-AASAVGSGERRG-------GGPVFPAPVVGSGGATSGKLL 258
+Y ES + S F A + GE + + S +T L
Sbjct: 147 SYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQLTEHEYLPSNSSTEHDRL 206
Query: 259 LEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQDPD 318
+ E+ G+ + RP Y+ PSIM K W++VK P + D
Sbjct: 207 --STEMASQDGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVK-----PERLEQACEGMD 259
Query: 319 LEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPDKGEEQVNFC 378
+ +E + + + E S G E I + + +E ++ +E N+
Sbjct: 260 VHATYDEHQVTESINTVQTEHTVQPS------GVEEDFHIGEKKVEAEFDEQADES-NYD 312
Query: 379 ESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSS 438
E + +G + +++ G H L N +V +S
Sbjct: 313 EQVDFYG--------SSMEEFSGERSDGNLIGHRQEAALAAGYSENIEMVTGIKEEASHL 364
Query: 439 QAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLCHCGKAFSHKS 498
+ G + S + +G P G G CGK F K
Sbjct: 365 GFSATDKLYPCQCGK-SFTHKSQRDRHMSMHLGLRPYGCGV----------CGKKFKMKH 413
Query: 499 MRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMR 558
H+ +H ++P++C +C AK+FMWRDSF R
Sbjct: 414 HLVGHMKIHTGIKPYECNIC----------------------------AKRFMWRDSFHR 445
Query: 559 HRGHCERRH 567
H C + +
Sbjct: 446 HVTSCTKSY 454
>gi|14249464 zinc finger and BTB domain containing 45 [Homo sapiens]
Length = 511
Score = 152 bits (384), Expect = 9e-37
Identities = 150/572 (26%), Positives = 216/572 (37%), Gaps = 124/572 (21%)
Query: 28 AAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVL 87
A AV H+ + +LLE+LN QRL G CDV++R++ RAHR VLAA SP+F D++L
Sbjct: 4 AEAVHHIHLQNFSRSLLETLNGQRLGGHFCDVTVRIREASLRAHRCVLAAGSPFFQDKLL 63
Query: 88 LKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELL 147
L G + I +P V+ ++ Y+G L +A + + LT SVL++ ++D+CT+++
Sbjct: 64 L-GHSEIRVPPVVPAQTVRQLVEFLYSGSLVVAQGEALQVLTAASVLRIQTVIDECTQII 122
Query: 148 REGRASATTTITTAAATSVTVPGAGV-------------PSGSGGTV------APATMGS 188
RA T+ T T V P A P G G PA +
Sbjct: 123 ARARAPGTSA-PTPLPTPVPPPLAPAQLRHRLRHLLAARPPGHPGAAHSRKQRQPARLQL 181
Query: 189 ARSHASSRA-SENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRG-GGPVFPAPV 246
++A + PS S R D S E G G G P FP
Sbjct: 182 PAPPTPAKAEGPDADPSLSAAPDDRGDEDDEESDDETDGEDGEGGGPGEGQAPPSFP--- 238
Query: 247 VGSGGATSGKLLLEADELCDDGGDGRG-AVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGN 305
+G L AD C++ G A GAG +++ G+
Sbjct: 239 ----DCAAGFLTAAADSACEEPPAPTGLADYSGAGRD----------------FLRGAGS 278
Query: 306 CPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISDVRTLS 365
E+ D ++ DED VP G E + + + S
Sbjct: 279 A---------------EDVFPDSYVSTWHDED------GAVPEGCPTETPVQPDCILSGS 317
Query: 366 EPPDKGEEQVNFCESSNDFGPYEGGGPVA----GLDDSGGPTPSSYAPSHPPRPLLPLDM 421
PP G G PVA L G P P APS P
Sbjct: 318 RPP----------------GVKTPGPPVALFPFHLGAPGPPAPPPSAPSGP--------- 352
Query: 422 QGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSV-----GGVPGG 476
AP PP T +G + P + G P
Sbjct: 353 ------------------APAPPPAFYPTLQPEAAPSTQLGEVPAPSAAPTTAPSGTPAR 394
Query: 477 TGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHT 536
T + HC K FS + +H+ +H +P C VC + F ++ +L +HM THT
Sbjct: 395 TPGAEPPTYECSHCRKTFSSRKNYTKHMFIHSGEKPHQCAVCWRSFSLRDYLLKHMVTHT 454
Query: 537 GLKPYECGVCAKKFMWRDSFMRHRGHCERRHR 568
G++ ++C VCAK+F + S H R HR
Sbjct: 455 GVRAFQCAVCAKRFTQKSSLNVHM----RTHR 482
>gi|149944640 zinc finger and BTB domain containing 34 [Homo
sapiens]
Length = 500
Score = 133 bits (334), Expect = 6e-31
Identities = 79/243 (32%), Positives = 124/243 (51%), Gaps = 12/243 (4%)
Query: 26 LPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQ 85
+ +++ + PE +S +L LN+ RLQG+LCD+ + +QG+ FRAH+AVLAASSPYF D
Sbjct: 1 MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDH 60
Query: 86 VLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTE 145
L M+ +S+ + +P FE +L+ YTGR+S+ D+V+FLT S LQM ++DKCT+
Sbjct: 61 SALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQ 120
Query: 146 LLREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSS 205
+L S + I+ SVTV P G + + + S+ + P++
Sbjct: 121 ILE----SIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTA 176
Query: 206 SN--YFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATSGKLLLEADE 263
S+ S S QE G +R G V + G G LL+ +
Sbjct: 177 SSDLRMETTPSKALRSRLQEE------GHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQ 230
Query: 264 LCD 266
+ +
Sbjct: 231 ITE 233
Score = 72.4 bits (176), Expect = 1e-12
Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Query: 483 NKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPY 541
N+ +C +CGK+F+ K DRH+ +H+ + PF C C KK+ K L H++ HT KP+
Sbjct: 369 NERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPF 428
Query: 542 ECGVCAKKFMWRDSFMRH 559
C +C K F ++ + +H
Sbjct: 429 RCEICGKCFPFQGTLNQH 446
Score = 43.5 bits (101), Expect = 6e-04
Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
Query: 486 FLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHM-KTHTGL 538
F+C CGK ++ K + H+ H + +PF C +C K F + L +H+ K H G+
Sbjct: 400 FVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGV 454
>gi|170650685 zinc finger and BTB domain containing 37 isoform a
[Homo sapiens]
Length = 503
Score = 126 bits (317), Expect = 5e-29
Identities = 55/116 (47%), Positives = 85/116 (73%)
Query: 32 VHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGM 91
+ + P+ ++++L LNQ R+QG+LCD+ + VQG+ FRAH+ VLAASSPYF D + L M
Sbjct: 7 IQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEM 66
Query: 92 TSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELL 147
+++S+ + +P FE +L+ YTGR+ + ADI+++LT S LQM HI+DKCT++L
Sbjct: 67 STVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQIL 122
Score = 72.8 bits (177), Expect = 9e-13
Identities = 28/71 (39%), Positives = 43/71 (60%)
Query: 489 HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAK 548
+C K+F+ K DRH+ +H+ + PF C +C KK+ K L H++ HTG KP+ C VC K
Sbjct: 377 YCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGK 436
Query: 549 KFMWRDSFMRH 559
F ++ +H
Sbjct: 437 SFPFQAILNQH 447
Score = 47.4 bits (111), Expect = 4e-05
Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 486 FLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHM-KTHTGLKPYE 542
F+C CGK ++ K + H+ H +PF C VC K F + L +H K H G P E
Sbjct: 401 FVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLE 459
Score = 43.9 bits (102), Expect = 5e-04
Identities = 17/45 (37%), Positives = 23/45 (51%)
Query: 515 CPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH 559
C C K F K L HM+ H G+ P+ C +C KK+ +D H
Sbjct: 375 CIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYH 419
>gi|14210530 zinc finger and BTB domain containing 37 isoform b
[Homo sapiens]
Length = 361
Score = 126 bits (317), Expect = 5e-29
Identities = 55/116 (47%), Positives = 85/116 (73%)
Query: 32 VHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGM 91
+ + P+ ++++L LNQ R+QG+LCD+ + VQG+ FRAH+ VLAASSPYF D + L M
Sbjct: 7 IQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEM 66
Query: 92 TSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELL 147
+++S+ + +P FE +L+ YTGR+ + ADI+++LT S LQM HI+DKCT++L
Sbjct: 67 STVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQIL 122
>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
Length = 733
Score = 124 bits (310), Expect = 3e-28
Identities = 163/656 (24%), Positives = 226/656 (34%), Gaps = 135/656 (20%)
Query: 37 PEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISL 96
P + LL LN QR +G LCDV I VQ FRAH+ VLAASS Y V+ + ++
Sbjct: 27 PGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLNLD- 85
Query: 97 PSVMDPGAFETVLASAYTGRLS-----MAAADIVN--------FLTVGSVLQMWHIVDKC 143
++ P F VL YTGRL+ AAA + L S LQ+ +V C
Sbjct: 86 HDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQIPDLVALC 145
Query: 144 TELLRE-------------------------GRASATTTITTAAATSVTVPGAGVPSGSG 178
+ L+ G +AT I + V P
Sbjct: 146 KKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPPAAEPPS 205
Query: 179 GTVAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGG 238
G A A +AS +S SP D S S AA ER
Sbjct: 206 GPEAAVNTHCAELYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELP 265
Query: 239 GPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWV 298
P G L L + +P ++ P P
Sbjct: 266 PRPDSPPSAGPAAYKEPPLALPS--------------LPPLPFQKLEEAAPPSDP----- 306
Query: 299 YVKRGGNCPAPTP------------LVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRV 346
+ G P P P + +P L +E + EE GG + V
Sbjct: 307 -FRGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAV 365
Query: 347 PVGGGPEATLSISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSS 406
GG P + P G + ++ SS + G E P G + G P P
Sbjct: 366 SPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLE-GYPCPH- 423
Query: 407 YAPSHPPRPLLPLDMQGNQILV-------FPSSSSSSSSQAPGQPPGNQAEHGAVTVGGT 459
A P + G+ + V FPSS ++ +A +G
Sbjct: 424 LAYGEP-------ESFGDNLYVCIPCGKGFPSSEQLNA-HVEAHVEEEEALYGRAEAAEV 475
Query: 460 SVGSLGVP-------GSVGGVPGGTG---------SGDGN-----------------KIF 486
+ G+ G+ V G PGG G S D + + +
Sbjct: 476 AAGAAGLGPPFGGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPY 535
Query: 487 LCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGV 545
C CGK F+ + RH+ HL L+PF C C +F ++ LTEHM+ H+G KPYEC V
Sbjct: 536 PCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQV 595
Query: 546 CAKKFMWRDSFMRHRGHCERRHRLGGVGAVPG--------PGTPTGPSLPSKRESP 593
C KF + + + H + H +GG G PG P GP K + P
Sbjct: 596 CGGKFAQQRNLISHM----KMHAVGGAAGAAGALAGLGGLPGVP-GPDGKGKLDFP 646
Score = 36.2 bits (82), Expect = 0.095
Identities = 26/73 (35%), Positives = 29/73 (39%), Gaps = 5/73 (6%)
Query: 554 DSFMRHRGH-CERRHRLGGVGAVPGPGTPTG----PSLPSKRESPGVGGGSGDEASAATP 608
D R RG ER GG AV G P G P P + PG GG D S++
Sbjct: 343 DELGRERGSPSERCEERGGDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEE 402
Query: 609 PSSRRVWSPPRVH 621
S SPP H
Sbjct: 403 TGSSEDPSPPGGH 415
>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
Length = 714
Score = 124 bits (310), Expect = 3e-28
Identities = 163/656 (24%), Positives = 226/656 (34%), Gaps = 135/656 (20%)
Query: 37 PEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISL 96
P + LL LN QR +G LCDV I VQ FRAH+ VLAASS Y V+ + ++
Sbjct: 8 PGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLNLD- 66
Query: 97 PSVMDPGAFETVLASAYTGRLS-----MAAADIVN--------FLTVGSVLQMWHIVDKC 143
++ P F VL YTGRL+ AAA + L S LQ+ +V C
Sbjct: 67 HDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQIPDLVALC 126
Query: 144 TELLRE-------------------------GRASATTTITTAAATSVTVPGAGVPSGSG 178
+ L+ G +AT I + V P
Sbjct: 127 KKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVGPPPPPAAEPPS 186
Query: 179 GTVAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGG 238
G A A +AS +S SP D S S AA ER
Sbjct: 187 GPEAAVNTHCAELYASGPGPAAALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELP 246
Query: 239 GPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWV 298
P G L L + +P ++ P P
Sbjct: 247 PRPDSPPSAGPAAYKEPPLALPS--------------LPPLPFQKLEEAAPPSDP----- 287
Query: 299 YVKRGGNCPAPTP------------LVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRV 346
+ G P P P + +P L +E + EE GG + V
Sbjct: 288 -FRGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAV 346
Query: 347 PVGGGPEATLSISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSS 406
GG P + P G + ++ SS + G E P G + G P P
Sbjct: 347 SPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLE-GYPCPH- 404
Query: 407 YAPSHPPRPLLPLDMQGNQILV-------FPSSSSSSSSQAPGQPPGNQAEHGAVTVGGT 459
A P + G+ + V FPSS ++ +A +G
Sbjct: 405 LAYGEP-------ESFGDNLYVCIPCGKGFPSSEQLNA-HVEAHVEEEEALYGRAEAAEV 456
Query: 460 SVGSLGVP-------GSVGGVPGGTG---------SGDGN-----------------KIF 486
+ G+ G+ V G PGG G S D + + +
Sbjct: 457 AAGAAGLGPPFGGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPY 516
Query: 487 LCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGV 545
C CGK F+ + RH+ HL L+PF C C +F ++ LTEHM+ H+G KPYEC V
Sbjct: 517 PCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQV 576
Query: 546 CAKKFMWRDSFMRHRGHCERRHRLGGVGAVPG--------PGTPTGPSLPSKRESP 593
C KF + + + H + H +GG G PG P GP K + P
Sbjct: 577 CGGKFAQQRNLISHM----KMHAVGGAAGAAGALAGLGGLPGVP-GPDGKGKLDFP 627
Score = 36.2 bits (82), Expect = 0.095
Identities = 26/73 (35%), Positives = 29/73 (39%), Gaps = 5/73 (6%)
Query: 554 DSFMRHRGH-CERRHRLGGVGAVPGPGTPTG----PSLPSKRESPGVGGGSGDEASAATP 608
D R RG ER GG AV G P G P P + PG GG D S++
Sbjct: 324 DELGRERGSPSERCEERGGDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEE 383
Query: 609 PSSRRVWSPPRVH 621
S SPP H
Sbjct: 384 TGSSEDPSPPGGH 396
>gi|167234429 zinc finger and BTB domain containing 17 [Homo
sapiens]
Length = 803
Score = 106 bits (264), Expect = 7e-23
Identities = 133/537 (24%), Positives = 204/537 (37%), Gaps = 56/537 (10%)
Query: 34 VSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTS 93
+ FP+ + +LE LNQQR G LCD + V G F+AH+AVLAA S YF ++L
Sbjct: 1 MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYF--KMLFVDQKD 58
Query: 94 ISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRAS 153
+ + + VL YT +LS++ ++ + L V + LQM I+ C L
Sbjct: 59 VVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHAL------- 111
Query: 154 ATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSAR-----SHASSRASENQSPSSSNY 208
+ A T PG G A AT G + A+S S + S
Sbjct: 112 ------KSLAEPATSPG-------GNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTP 158
Query: 209 FSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATSGKLLLEADELCDDG 268
P Q AAS E + P P PV TSG EA+ +
Sbjct: 159 IGPSRDLKEERGGQAQSAASGAEQTE-KADAPREPPPVELKPDPTSGMAAAEAEAALSES 217
Query: 269 GDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQDPDLEEEEEEEDL 328
+ V P QK + G PA + E EE +
Sbjct: 218 SEQEMEVEPAR---------KGEEEQKEQEEQEEEGAGPAEVKEEGSQLENGEAPEENEN 268
Query: 329 VLTCEDDEDEELGGSSR-VPVGGGPEATLSISDVRTLSEPPDKGEEQVNFCESSNDFGPY 387
+ D +ELG +R + G + T S + + + D G+E + +
Sbjct: 269 EESAGTDSGQELGSEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIH 328
Query: 388 EGGGPVAGLDDSGGPTPSSYAPSHPP--RPLLPLDMQ--GNQILVFPSSSSSSSSQAPGQ 443
G P + + S + + +H PL P + G + S + + G+
Sbjct: 329 TGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLI-SLLNLHKKRHSGE 387
Query: 444 PPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLC-HCGKAFSHKSMRDR 502
+ G + T+ G+L V SG+ K + C +CG++FS + + R
Sbjct: 388 ARYRCEDCGKLF---TTSGNLKRHQLV-------HSGE--KPYQCDYCGRSFSDPTSKMR 435
Query: 503 HVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH 559
H+ H + CP C+KKF +L H+K H P +C C K+F + RH
Sbjct: 436 HLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRH 492
Score = 65.5 bits (158), Expect = 1e-10
Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K ++C HC + F+ RHV +H +P C +C K F L H++ HTG KP
Sbjct: 498 GEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKP 557
Query: 541 YECGVCAKKFMWRDSFMRHRGH 562
Y C C K+F+ H H
Sbjct: 558 YVCERCGKRFVQSSQLANHIRH 579
Score = 64.3 bits (155), Expect = 3e-10
Identities = 31/79 (39%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K ++C CGK F S H+ H N+RP C VC+K F L++H+ HTG KP
Sbjct: 554 GEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKP 613
Query: 541 YECGVCAKKFMWRDSFMRH 559
Y C C + F D+ H
Sbjct: 614 YLCDKCGRGFNRVDNLRSH 632
Score = 62.0 bits (149), Expect = 2e-09
Identities = 57/214 (26%), Positives = 78/214 (36%), Gaps = 21/214 (9%)
Query: 353 EATLSISDVRTLS-EPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSH 411
EA LS S + + EP KGEE+ E + EG GP A + + G + AP
Sbjct: 211 EAALSESSEQEMEVEPARKGEEEQKEQEEQEE----EGAGP-AEVKEEGSQLENGEAPEE 265
Query: 412 PPRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGS-- 469
N+ S S+A G G + G+ + G
Sbjct: 266 ----------NENEESAGTDSGQELGSEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEF 315
Query: 470 --VGGVPGGTGSGDGNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKH 526
G G K F C C KAFS + H H L+P+ C C K +++
Sbjct: 316 THTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLIS 375
Query: 527 HLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHR 560
L H K H+G Y C C K F + RH+
Sbjct: 376 LLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQ 409
Score = 60.5 bits (145), Expect = 5e-09
Identities = 24/70 (34%), Positives = 37/70 (52%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGKAF+ S HV H +P+ C C K+F L H++ H ++P++C VC+K
Sbjct: 535 CGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKA 594
Query: 550 FMWRDSFMRH 559
F+ +H
Sbjct: 595 FVNVGDLSKH 604
Score = 55.8 bits (133), Expect = 1e-07
Identities = 24/70 (34%), Positives = 36/70 (51%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGK F+ RH+ +H +P+ C C ++F L H++ HTG KP +C +C K
Sbjct: 479 CGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKA 538
Query: 550 FMWRDSFMRH 559
F S + H
Sbjct: 539 FTQASSLIAH 548
Score = 54.3 bits (129), Expect = 3e-07
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 481 DGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLK 539
D +K C HC K F+ H+ +H+ P C C K+F +L H++ H+G K
Sbjct: 441 DTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEK 500
Query: 540 PYECGVCAKKFMWRDSFMRH 559
PY C C ++F + RH
Sbjct: 501 PYVCIHCQRQFADPGALQRH 520
Score = 35.4 bits (80), Expect = 0.16
Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKT-HTG 537
C KAF + +H+ +H +P+ C C + F +L H+KT H G
Sbjct: 591 CSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQG 639
>gi|16418383 transcriptional repressor NAC1 [Homo sapiens]
Length = 527
Score = 98.6 bits (244), Expect = 2e-20
Identities = 69/209 (33%), Positives = 98/209 (46%), Gaps = 9/209 (4%)
Query: 29 AAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLL 88
A + + P +++LE LN+QRLQG CDVS+ V+G F+AHRAVLAASS YF D
Sbjct: 2 AQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNN 61
Query: 89 KGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTE-LL 147
+ LP+ + P +F+ +L+ YTGRLSM D + LQ+ I++K TE L
Sbjct: 62 SRSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFFL 121
Query: 148 REGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSSSN 207
+ S + A + P + V SG + SR Q S S
Sbjct: 122 KVSSPSCDSQGLHAEEAPSSEPQSPVAQTSGWPACSTPLPLV-----SRVKTEQQESDSV 176
Query: 208 YFSPRESTDFSSSSQEAFAASAVGSGERR 236
P + S +E A G+G R+
Sbjct: 177 QCMPVAKRLWDSGQKE---AGGGGNGSRK 202
>gi|21389533 BTB (POZ) domain containing 14A [Homo sapiens]
Length = 587
Score = 98.2 bits (243), Expect = 2e-20
Identities = 49/117 (41%), Positives = 74/117 (63%)
Query: 31 VVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKG 90
++H+ P + +L LN+QRL G CDVSI V+G+ F+AHRAVLAASS YF D
Sbjct: 4 MLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNS 63
Query: 91 MTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELL 147
++ LP + P F+ +L+ YTGRL+M A++ + + LQ+ HIV++ T+L+
Sbjct: 64 KSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLM 120
>gi|66932932 promyelocytic leukemia zinc finger protein [Homo
sapiens]
Length = 673
Score = 97.8 bits (242), Expect = 3e-20
Identities = 125/549 (22%), Positives = 195/549 (35%), Gaps = 81/549 (14%)
Query: 24 LPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFH 83
+ L ++ + P + LL NQ RL G LCDV I V +EF AHR VLA +S F
Sbjct: 1 MDLTKMGMIQLQNPSHPTGLLCKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMF- 59
Query: 84 DQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKC 143
++L + + P F+ +L AYT L A D+ + L +L++ ++ ++C
Sbjct: 60 -EILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQC 118
Query: 144 TELLREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSP 203
++L +AS T T+ G H+S E+
Sbjct: 119 LKMLETIQASDDND------TEATMADGGAEEEEDRKARYLKNIFISKHSS---EESGYA 169
Query: 204 SSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATSGKLLLEADE 263
S + P D S S +F SA+ P T G+ LL+
Sbjct: 170 SVAGQSLPGPMVDQSPSVSTSFGLSAMS-----------PTKAAVDSLMTIGQSLLQ--- 215
Query: 264 LCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQD--PDLEE 321
G + P AG PT P G T ++ D P +
Sbjct: 216 ---------GTLQPPAGPEEPTLAGGGRHP----------GVAEVKTEMMQVDEVPSQDS 256
Query: 322 EEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPDKGEEQVNFCESS 381
E + D+ EE G G P + I+ R L ++ EQV
Sbjct: 257 PGAAESSISGGMGDKVEERGKEG----PGTPTRSSVITSARELHYGREESAEQVP----- 307
Query: 382 NDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAP 441
P E G G + P P + + P + + + +L PSS +S P
Sbjct: 308 ---PPAEAGQAPTGRPEHPAPPPEKHLGIYSVLP----NHKADAVLSMPSSVTSGLHVQP 360
Query: 442 GQPPGNQAEHGAVTVGGTSVGSLGVPG--------SVGGVPGGTGSGDGNKIFLCH-CGK 492
AV++ ++ G L G +G + G S C CG
Sbjct: 361 AL---------AVSMDFSTYGGLLPQGFIQRELFSKLGELAVGMKSESRTIGEQCSVCGV 411
Query: 493 AFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHT-GLKPYECGVCAKKFM 551
++H +H ++ + C +C K+F L H+ H+ G K + C C +F
Sbjct: 412 ELPDNEAVEQHRKLHSGMKTYGCELCGKRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFS 471
Query: 552 WRDSFMRHR 560
D+ HR
Sbjct: 472 KEDALETHR 480
Score = 65.1 bits (157), Expect = 2e-10
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Query: 479 SGDGNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTG 537
S G+ + C CG F +S H +H +P++C C KKF +KH L H + HTG
Sbjct: 539 SHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTG 598
Query: 538 LKPYECGVCAKKFMWRDSFMRH 559
KP+EC +C ++ + ++H
Sbjct: 599 EKPFECKLCHQRSRDYSAMIKH 620
Score = 63.5 bits (153), Expect = 6e-10
Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C+ CGK FS K + H +H +PF+C +C+++ + + +H++TH G P
Sbjct: 570 GEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASP 629
Query: 541 YECGVCAKKFMWRDSFMRH-RGH 562
Y+C +C + S +H +GH
Sbjct: 630 YQCTICTEYCPSLSSMQKHMKGH 652
Score = 62.0 bits (149), Expect = 2e-09
Identities = 27/84 (32%), Positives = 41/84 (48%)
Query: 477 TGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHT 536
T +G +F CGK F +S +H+ +H +R + C CN+ F L H+++HT
Sbjct: 482 THTGTDMAVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSHT 541
Query: 537 GLKPYECGVCAKKFMWRDSFMRHR 560
G PYEC C F + H+
Sbjct: 542 GDHPYECEFCGSCFRDESTLKSHK 565
Score = 60.5 bits (145), Expect = 5e-09
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + ++C C + F + RH+ H P++C C F+ + L H + HTG KP
Sbjct: 514 GVRSYICSECNRTFPSHTALKRHLRSHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKP 573
Query: 541 YECGVCAKKFMWRDSFMRH 559
YEC C KKF + H
Sbjct: 574 YECNGCGKKFSLKHQLETH 592
>gi|21359888 promyelocytic leukemia zinc finger protein [Homo
sapiens]
Length = 673
Score = 97.8 bits (242), Expect = 3e-20
Identities = 125/549 (22%), Positives = 195/549 (35%), Gaps = 81/549 (14%)
Query: 24 LPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFH 83
+ L ++ + P + LL NQ RL G LCDV I V +EF AHR VLA +S F
Sbjct: 1 MDLTKMGMIQLQNPSHPTGLLCKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMF- 59
Query: 84 DQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKC 143
++L + + P F+ +L AYT L A D+ + L +L++ ++ ++C
Sbjct: 60 -EILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQC 118
Query: 144 TELLREGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSP 203
++L +AS T T+ G H+S E+
Sbjct: 119 LKMLETIQASDDND------TEATMADGGAEEEEDRKARYLKNIFISKHSS---EESGYA 169
Query: 204 SSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATSGKLLLEADE 263
S + P D S S +F SA+ P T G+ LL+
Sbjct: 170 SVAGQSLPGPMVDQSPSVSTSFGLSAMS-----------PTKAAVDSLMTIGQSLLQ--- 215
Query: 264 LCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQD--PDLEE 321
G + P AG PT P G T ++ D P +
Sbjct: 216 ---------GTLQPPAGPEEPTLAGGGRHP----------GVAEVKTEMMQVDEVPSQDS 256
Query: 322 EEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPDKGEEQVNFCESS 381
E + D+ EE G G P + I+ R L ++ EQV
Sbjct: 257 PGAAESSISGGMGDKVEERGKEG----PGTPTRSSVITSARELHYGREESAEQVP----- 307
Query: 382 NDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAP 441
P E G G + P P + + P + + + +L PSS +S P
Sbjct: 308 ---PPAEAGQAPTGRPEHPAPPPEKHLGIYSVLP----NHKADAVLSMPSSVTSGLHVQP 360
Query: 442 GQPPGNQAEHGAVTVGGTSVGSLGVPG--------SVGGVPGGTGSGDGNKIFLCH-CGK 492
AV++ ++ G L G +G + G S C CG
Sbjct: 361 AL---------AVSMDFSTYGGLLPQGFIQRELFSKLGELAVGMKSESRTIGEQCSVCGV 411
Query: 493 AFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHT-GLKPYECGVCAKKFM 551
++H +H ++ + C +C K+F L H+ H+ G K + C C +F
Sbjct: 412 ELPDNEAVEQHRKLHSGMKTYGCELCGKRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFS 471
Query: 552 WRDSFMRHR 560
D+ HR
Sbjct: 472 KEDALETHR 480
Score = 65.1 bits (157), Expect = 2e-10
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Query: 479 SGDGNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTG 537
S G+ + C CG F +S H +H +P++C C KKF +KH L H + HTG
Sbjct: 539 SHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTG 598
Query: 538 LKPYECGVCAKKFMWRDSFMRH 559
KP+EC +C ++ + ++H
Sbjct: 599 EKPFECKLCHQRSRDYSAMIKH 620
Score = 63.5 bits (153), Expect = 6e-10
Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C+ CGK FS K + H +H +PF+C +C+++ + + +H++TH G P
Sbjct: 570 GEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASP 629
Query: 541 YECGVCAKKFMWRDSFMRH-RGH 562
Y+C +C + S +H +GH
Sbjct: 630 YQCTICTEYCPSLSSMQKHMKGH 652
Score = 62.0 bits (149), Expect = 2e-09
Identities = 27/84 (32%), Positives = 41/84 (48%)
Query: 477 TGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHT 536
T +G +F CGK F +S +H+ +H +R + C CN+ F L H+++HT
Sbjct: 482 THTGTDMAVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSHT 541
Query: 537 GLKPYECGVCAKKFMWRDSFMRHR 560
G PYEC C F + H+
Sbjct: 542 GDHPYECEFCGSCFRDESTLKSHK 565
Score = 60.5 bits (145), Expect = 5e-09
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + ++C C + F + RH+ H P++C C F+ + L H + HTG KP
Sbjct: 514 GVRSYICSECNRTFPSHTALKRHLRSHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKP 573
Query: 541 YECGVCAKKFMWRDSFMRH 559
YEC C KKF + H
Sbjct: 574 YECNGCGKKFSLKHQLETH 592
>gi|52694665 zinc finger and BTB domain containing 20 [Homo sapiens]
Length = 668
Score = 96.3 bits (238), Expect = 8e-20
Identities = 50/159 (31%), Positives = 91/159 (57%), Gaps = 4/159 (2%)
Query: 34 VSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTS 93
++ ++++LE+LN+QR +G CDV++R+ G RAHR VLAA SP+F D++LL G +
Sbjct: 8 INLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKLLL-GYSD 66
Query: 94 ISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRAS 153
I +PSV+ + + ++ Y+G L ++ ++ + LT S+LQ+ ++D+CT ++ +
Sbjct: 67 IEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECTRIVSQNVGD 126
Query: 154 ATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSH 192
I + + P SG+ G + G +SH
Sbjct: 127 VFPGIQDSGQDT---PRGTPESGTSGQSSDTESGYLQSH 162
Score = 69.7 bits (169), Expect = 8e-12
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 446 GNQAEHGAVTVGGTSVGSLGVPG-----SVGGVPGGTGSGDGNKIFLCHCGKAFSHKSMR 500
G Q + V+ G S + +P S G +G G+ C K F+ K
Sbjct: 461 GQQTQFVTVSQPGLSTFTAQLPAPQPLASSAGHSTASGQGEKKPYECTLCNKTFTAKQNY 520
Query: 501 DRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH 559
+H+ +H +P C +C + F +K +L +HM THTG++ Y+C +C K+F + S H
Sbjct: 521 VKHMFVHTGEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVH 579
Score = 67.8 bits (164), Expect = 3e-11
Identities = 41/116 (35%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K C C ++FS K +H+ H +R + C +CNK+F K L HM+ H G K
Sbjct: 529 GEKPHQCSICWRSFSLKDYLIKHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKS 588
Query: 541 YECGVCAKKFMWRDSFMRHRGHCERRHRL-GGVGAVPGPGTPTGPSLPSKRESPGV 595
YEC +C KKF H+ ER L P GTP G ++ PGV
Sbjct: 589 YECYICKKKF-------SHKTLLERHVALHSASNGTPPAGTPPG----ARAGPPGV 633
>gi|46358366 zinc finger protein 746 [Homo sapiens]
Length = 644
Score = 95.1 bits (235), Expect = 2e-19
Identities = 57/165 (34%), Positives = 81/165 (49%), Gaps = 13/165 (7%)
Query: 433 SSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLCHCGK 492
S S+ ++ G P G+ G T GG S GS G GG GG + DG+ + CG+
Sbjct: 467 SLSAHQRSCGAPDGS----GPGTGGGGS-GS----GGGGGGSGGGSARDGSALRCGECGR 517
Query: 493 AFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMW 552
F+ + RH +H RPF C C K+F + L +H +THTG++P+ C VC K F+
Sbjct: 518 CFTRPAHLIRHRMLHTGERPFPCTECEKRFTERSKLIDHYRTHTGVRPFTCTVCGKSFIR 577
Query: 553 RDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGG 597
+D +H +R H G G PT P+ P +SP G
Sbjct: 578 KDHLRKH----QRNHAAGAKTPARGQPLPTPPAPPDPFKSPASKG 618
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/128 (29%), Positives = 47/128 (36%), Gaps = 13/128 (10%)
Query: 491 GKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKF 550
G+A S R N P P K F K L +H G +P+ C C K F
Sbjct: 408 GEAILDPSQAPRPFN-----EPCKYPGRTKGFGHKPGLKKHPAAPPGGRPFTCATCGKSF 462
Query: 551 MWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSGDEASAATPPS 610
+ S H+ C G GPGT G S S G GGGS + SA
Sbjct: 463 QLQVSLSAHQRSC-------GAPDGSGPGTGGGGS-GSGGGGGGSGGGSARDGSALRCGE 514
Query: 611 SRRVWSPP 618
R ++ P
Sbjct: 515 CGRCFTRP 522
>gi|32469509 zinc finger and BTB domain containing 12 [Homo sapiens]
Length = 459
Score = 94.0 bits (232), Expect = 4e-19
Identities = 86/296 (29%), Positives = 120/296 (40%), Gaps = 76/296 (25%)
Query: 307 PAPTPLV-------PQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSIS 359
P P PL+ P D DLE + EEED +DEDE++ V V E+ L ++
Sbjct: 171 PLPPPLLRPVKLEFPLDEDLELKAEEED------EDEDEDVSDICIVKV----ESALEVA 220
Query: 360 DVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSH--PPRPL- 416
L P G G GG V G G SS PS PP+ +
Sbjct: 221 --HRLKPPGGLG-------------GGLGIGGSVGG--HLGELAQSSVPPSTVAPPQGVV 263
Query: 417 -----LPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVG-SLGVPGSV 470
L D +G +L+ P +S + + E AV + G SLG GS
Sbjct: 264 KACYSLSEDAEGEGLLLIPGGRASVGATS------GLVEAAAVAMAARGAGGSLGAGGSR 317
Query: 471 GGVPGGTGSGDGNK--------------------------IFLC-HCGKAFSHKSMRDRH 503
G +PGG G+ K IF+C CGK F+H S +RH
Sbjct: 318 GPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHFIFMCPRCGKQFNHSSNLNRH 377
Query: 504 VNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH 559
+N+H ++ C +C K F K L +H+ H+G +PY C C +F + + RH
Sbjct: 378 MNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCDVRFAHKPAIRRH 433
Score = 93.2 bits (230), Expect = 7e-19
Identities = 52/154 (33%), Positives = 78/154 (50%), Gaps = 10/154 (6%)
Query: 31 VVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKG 90
V+ P +A L ++NQ R + + CDV+I +FR H+ +LAA SP+ DQ LL
Sbjct: 7 VLRFQLPGHEAATLRNMNQLRAEERFCDVTIVADSLKFRGHKVILAACSPFLRDQFLLNP 66
Query: 91 MTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTEL---- 146
+ + + + +L S YTG L A DIVN+LT S LQM H+V+KC
Sbjct: 67 SSELQVSLMHSARIVADLLLSCYTGALEFAVRDIVNYLTAASYLQMEHVVEKCRNALSQF 126
Query: 147 ------LREGRASATTTITTAAATSVTVPGAGVP 174
L+E S + +++ +AT +P A P
Sbjct: 127 IEPKIGLKEDGVSEASLVSSISATKSLLPPARTP 160
>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
sapiens]
Length = 1059
Score = 91.7 bits (226), Expect = 2e-18
Identities = 63/213 (29%), Positives = 86/213 (40%), Gaps = 34/213 (15%)
Query: 441 PGQPPGNQAEHGAVTVGGTSVGSLGVP----------GSVGGVPGGTGSGDGNKIFLCH- 489
P PP +E A G++ VP G+ GG+G+ K F C
Sbjct: 495 PPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGI 554
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CG+ F + RH +H +P CPVC K+F+ HL++H HT +PY+C +C K
Sbjct: 555 CGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKV 614
Query: 550 FMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSGDEASAATP- 608
F + S RHR + HRL A+ G LPS + +PG G SA
Sbjct: 615 FGYPQSLTRHR----QVHRLQLPCALAG-----AAGLPSTQGTPGACGPGASGTSAGPTD 665
Query: 609 -------------PSSRRVWSPPRVHKVEMGFG 628
P V S VH E +G
Sbjct: 666 GLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYG 698
Score = 75.5 bits (184), Expect = 1e-13
Identities = 69/242 (28%), Positives = 92/242 (38%), Gaps = 33/242 (13%)
Query: 400 GGPTPSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGT 459
G P P + + P +D+ G+Q L F + + PG PG A GA
Sbjct: 131 GAPPPPLFDAAFPTPQWGIVDLSGHQHL-FGNLKRGGPASGPGVTPGLGAPAGAP----- 184
Query: 460 SVGSLGVPGSVGGVPGGTGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCN 519
G L P P + D K K + + +L R F C VC
Sbjct: 185 --GPLPAPSQTPPGPPAAAACDPTKD-----DKGYFRRLK-------YLMERRFPCGVCQ 230
Query: 520 KKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHR--LGGVGAVPG 577
K FK HL +HM H+G +PYECGVC + + S +RHR R H+ G P
Sbjct: 231 KSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHR----RCHKDVPPAAGGPPQ 286
Query: 578 PG---TPTGPSLPSKRESPGVGGGSGDEASAATP----PSSRRVWSPPRVHKVEMGFGGG 630
PG P G P+ + + ATP PS+ +P V GGG
Sbjct: 287 PGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGG 346
Query: 631 GG 632
G
Sbjct: 347 DG 348
Score = 72.4 bits (176), Expect = 1e-12
Identities = 54/180 (30%), Positives = 72/180 (40%), Gaps = 18/180 (10%)
Query: 404 PSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGS 463
P++ P P L PL + +++ S+ S P P A S
Sbjct: 279 PAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAP---------SADG 329
Query: 464 LGVPGSVGGVPGGTGSGDGNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKF 522
P VG P TG GDG F C C K F S +H +H +PF C VC+K F
Sbjct: 330 SAAPAGVGVPPPATGGGDGP--FACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSF 387
Query: 523 KMKHHLTEHMKTHTG-LKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTP 581
+ L H+KTH+ L CG+C K F ++H + H G G P P P
Sbjct: 388 NRRESLKRHVKTHSADLLRLPCGICGKAFRDASYLLKH----QAAHAGAGAGG-PRPVYP 442
Score = 65.5 bits (158), Expect = 1e-10
Identities = 28/71 (39%), Positives = 38/71 (53%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGK F ++ RH H RP+ C VC + F +L +H HTG + ++CGVCAK+
Sbjct: 853 CGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKR 912
Query: 550 FMWRDSFMRHR 560
F S HR
Sbjct: 913 FAQSSSLAEHR 923
Score = 61.6 bits (148), Expect = 2e-09
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C C K F+ S H +H RP C C K F+ + +L EH + H G +
Sbjct: 900 GERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERA 959
Query: 541 YECGVCAKKFMWRDSFMRHR 560
Y C C K F + S +RH+
Sbjct: 960 YRCEHCGKGFFYLSSVLRHQ 979
Score = 59.7 bits (143), Expect = 8e-09
Identities = 53/177 (29%), Positives = 64/177 (36%), Gaps = 33/177 (18%)
Query: 413 PRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTV------GGTSVGSLGV 466
P LLP G Q P SS + A G E GA GG G V
Sbjct: 723 PERLLPPAPGGLQ----PPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAV 778
Query: 467 PGSVGGVPGG------TGSGDGNKIFL----------------CH-CGKAFSHKSMRDRH 503
G+ GG G G K FL C CG++F+ H
Sbjct: 779 AGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLH 838
Query: 504 VNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHR 560
H R F CPVC K+F L H + HT +PY CGVC + F+ +HR
Sbjct: 839 RRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHR 895
Score = 57.8 bits (138), Expect = 3e-08
Identities = 36/104 (34%), Positives = 47/104 (45%), Gaps = 5/104 (4%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRP-FDCPVCNKKFKMKHHLTEHMKTHTGLK 539
G + + C HCGK F + S RH H R CP C K FK + +H+ H G +
Sbjct: 956 GERAYRCEHCGKGFFYLSSVLRHQRAHEPPRAELRCPACLKAFKDPGYFRKHLAAHQGGR 1015
Query: 540 PYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTG 583
P+ C C + F +HR + LGG GA G GT G
Sbjct: 1016 PFRCSSCGEGFANTYGLKKHR-LAHKAENLGGPGA--GAGTLAG 1056
Score = 55.8 bits (133), Expect = 1e-07
Identities = 23/71 (32%), Positives = 33/71 (46%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CG+ F +H +H R F C VC K+F L EH + H +P C C K
Sbjct: 881 CGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKT 940
Query: 550 FMWRDSFMRHR 560
F +R + + H+
Sbjct: 941 FRYRSNLLEHQ 951
Score = 39.7 bits (91), Expect = 0.009
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 2/73 (2%)
Query: 465 GVPGSVGGVPGGTGSG--DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKF 522
G PG+ G GT +G DG CG+ F H +H+ +P+ C C K F
Sbjct: 647 GTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTF 706
Query: 523 KMKHHLTEHMKTH 535
+L H H
Sbjct: 707 GFIENLMWHKLVH 719
Score = 38.9 bits (89), Expect = 0.015
Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 6/96 (6%)
Query: 513 FDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHR-GHCERRHRLGG 571
+ C C + F H+ H + H KPY C C K F + ++ M H+ H RL
Sbjct: 669 YACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLVHQAAPERL-- 726
Query: 572 VGAVPGPGTPTGPSLPSKRESPGV-GGGSGDEASAA 606
P PG P S ++ V G E AA
Sbjct: 727 --LPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAA 760
>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
sapiens]
Length = 1059
Score = 91.7 bits (226), Expect = 2e-18
Identities = 63/213 (29%), Positives = 86/213 (40%), Gaps = 34/213 (15%)
Query: 441 PGQPPGNQAEHGAVTVGGTSVGSLGVP----------GSVGGVPGGTGSGDGNKIFLCH- 489
P PP +E A G++ VP G+ GG+G+ K F C
Sbjct: 495 PPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGI 554
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CG+ F + RH +H +P CPVC K+F+ HL++H HT +PY+C +C K
Sbjct: 555 CGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKV 614
Query: 550 FMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTGPSLPSKRESPGVGGGSGDEASAATP- 608
F + S RHR + HRL A+ G LPS + +PG G SA
Sbjct: 615 FGYPQSLTRHR----QVHRLQLPCALAG-----AAGLPSTQGTPGACGPGASGTSAGPTD 665
Query: 609 -------------PSSRRVWSPPRVHKVEMGFG 628
P V S VH E +G
Sbjct: 666 GLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYG 698
Score = 75.5 bits (184), Expect = 1e-13
Identities = 69/242 (28%), Positives = 92/242 (38%), Gaps = 33/242 (13%)
Query: 400 GGPTPSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGT 459
G P P + + P +D+ G+Q L F + + PG PG A GA
Sbjct: 131 GAPPPPLFDAAFPTPQWGIVDLSGHQHL-FGNLKRGGPASGPGVTPGLGAPAGAP----- 184
Query: 460 SVGSLGVPGSVGGVPGGTGSGDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCN 519
G L P P + D K K + + +L R F C VC
Sbjct: 185 --GPLPAPSQTPPGPPAAAACDPTKD-----DKGYFRRLK-------YLMERRFPCGVCQ 230
Query: 520 KKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHR--LGGVGAVPG 577
K FK HL +HM H+G +PYECGVC + + S +RHR R H+ G P
Sbjct: 231 KSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHR----RCHKDVPPAAGGPPQ 286
Query: 578 PG---TPTGPSLPSKRESPGVGGGSGDEASAATP----PSSRRVWSPPRVHKVEMGFGGG 630
PG P G P+ + + ATP PS+ +P V GGG
Sbjct: 287 PGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGG 346
Query: 631 GG 632
G
Sbjct: 347 DG 348
Score = 72.4 bits (176), Expect = 1e-12
Identities = 54/180 (30%), Positives = 72/180 (40%), Gaps = 18/180 (10%)
Query: 404 PSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGS 463
P++ P P L PL + +++ S+ S P P A S
Sbjct: 279 PAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAP---------SADG 329
Query: 464 LGVPGSVGGVPGGTGSGDGNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKF 522
P VG P TG GDG F C C K F S +H +H +PF C VC+K F
Sbjct: 330 SAAPAGVGVPPPATGGGDGP--FACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSF 387
Query: 523 KMKHHLTEHMKTHTG-LKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTP 581
+ L H+KTH+ L CG+C K F ++H + H G G P P P
Sbjct: 388 NRRESLKRHVKTHSADLLRLPCGICGKAFRDASYLLKH----QAAHAGAGAGG-PRPVYP 442
Score = 65.5 bits (158), Expect = 1e-10
Identities = 28/71 (39%), Positives = 38/71 (53%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGK F ++ RH H RP+ C VC + F +L +H HTG + ++CGVCAK+
Sbjct: 853 CGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKR 912
Query: 550 FMWRDSFMRHR 560
F S HR
Sbjct: 913 FAQSSSLAEHR 923
Score = 61.6 bits (148), Expect = 2e-09
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C C K F+ S H +H RP C C K F+ + +L EH + H G +
Sbjct: 900 GERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERA 959
Query: 541 YECGVCAKKFMWRDSFMRHR 560
Y C C K F + S +RH+
Sbjct: 960 YRCEHCGKGFFYLSSVLRHQ 979
Score = 60.8 bits (146), Expect = 4e-09
Identities = 37/104 (35%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRP-FDCPVCNKKFKMKHHLTEHMKTHTGLK 539
G + + C HCGK F + S RH H RP CP C K FK + +H+ H G +
Sbjct: 956 GERAYRCEHCGKGFFYLSSVLRHQRAHEPPRPELRCPACLKAFKDPGYFRKHLAAHQGGR 1015
Query: 540 PYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGTPTG 583
P+ C C + F +HR + LGG GA G GT G
Sbjct: 1016 PFRCSSCGEGFANTYGLKKHR-LAHKAENLGGPGA--GAGTLAG 1056
Score = 59.7 bits (143), Expect = 8e-09
Identities = 53/177 (29%), Positives = 64/177 (36%), Gaps = 33/177 (18%)
Query: 413 PRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTV------GGTSVGSLGV 466
P LLP G Q P SS + A G E GA GG G V
Sbjct: 723 PERLLPPAPGGLQ----PPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAV 778
Query: 467 PGSVGGVPGG------TGSGDGNKIFL----------------CH-CGKAFSHKSMRDRH 503
G+ GG G G K FL C CG++F+ H
Sbjct: 779 AGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLH 838
Query: 504 VNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHR 560
H R F CPVC K+F L H + HT +PY CGVC + F+ +HR
Sbjct: 839 RRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHR 895
Score = 55.8 bits (133), Expect = 1e-07
Identities = 23/71 (32%), Positives = 33/71 (46%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CG+ F +H +H R F C VC K+F L EH + H +P C C K
Sbjct: 881 CGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKT 940
Query: 550 FMWRDSFMRHR 560
F +R + + H+
Sbjct: 941 FRYRSNLLEHQ 951
Score = 39.7 bits (91), Expect = 0.009
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 2/73 (2%)
Query: 465 GVPGSVGGVPGGTGSG--DGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKF 522
G PG+ G GT +G DG CG+ F H +H+ +P+ C C K F
Sbjct: 647 GTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTF 706
Query: 523 KMKHHLTEHMKTH 535
+L H H
Sbjct: 707 GFIENLMWHKLVH 719
Score = 38.9 bits (89), Expect = 0.015
Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 6/96 (6%)
Query: 513 FDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHR-GHCERRHRLGG 571
+ C C + F H+ H + H KPY C C K F + ++ M H+ H RL
Sbjct: 669 YACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLVHQAAPERL-- 726
Query: 572 VGAVPGPGTPTGPSLPSKRESPGV-GGGSGDEASAA 606
P PG P S ++ V G E AA
Sbjct: 727 --LPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAA 760
>gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 87.4 bits (215), Expect = 4e-17
Identities = 53/166 (31%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 465 GVPGSVGGVPGGTGSGDGNKIFLCHC-GKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFK 523
G P PGG ++ F C C GK F HK H +H RP CP C K+F
Sbjct: 218 GRPAVTAPRPGGDAV---DRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFT 274
Query: 524 MKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGT--- 580
K +LT H + HTG KPY C C ++F + + + H +R G A PGPG+
Sbjct: 275 NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSE--GSAQAAPGPGSPQL 332
Query: 581 PTGPSLPSKRESPGVGGGSGDEASAATPPSSRR--VWSPPRVHKVE 624
P GP + +P V E PP + + +PP ++ +
Sbjct: 333 PAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCD 378
Score = 69.7 bits (169), Expect = 8e-12
Identities = 30/76 (39%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 486 FLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECG 544
F+C CGKAF HK H +H +P+ CP C K F K +L H + HTG +PY C
Sbjct: 459 FVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACP 518
Query: 545 VCAKKFMWRDSFMRHR 560
C + F + + + HR
Sbjct: 519 DCDRSFSQKSNLITHR 534
Score = 67.4 bits (163), Expect = 4e-11
Identities = 33/80 (41%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CG+ FS S H H RPF CP C K F+ K +L H + HTG KP
Sbjct: 427 GERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKP 486
Query: 541 YECGVCAKKFMWRDSFMRHR 560
Y C C K F + + + HR
Sbjct: 487 YVCPDCGKAFSQKSNLVSHR 506
Score = 60.5 bits (145), Expect = 5e-09
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K ++C CGKAFS KS H +H RP+ CP C++ F K +L H K+H
Sbjct: 483 GEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C +C + F + + H+
Sbjct: 543 FCCAICGQTFDDEERLLAHQ 562
Score = 58.5 bits (140), Expect = 2e-08
Identities = 24/71 (33%), Positives = 33/71 (46%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CG++F + H H RPF C C K F K HL H + H+G +P+ C C ++
Sbjct: 380 CGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRR 439
Query: 550 FMWRDSFMRHR 560
F HR
Sbjct: 440 FSQGSHLAAHR 450
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CGK F K+ H +H RPF C C ++F HL H + H +P
Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRP 458
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C K F + HR
Sbjct: 459 FVCPDCGKAFRHKPYLAAHR 478
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 486 FLCH-CGKAFSHKSMRDRHVNMHLNL-RPFDCPVCNKKFKMKHHLTEHMK----THTGLK 539
F CH CG++F H+ H RP CP C ++F + L H++ +
Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHPPAPEAR 175
Query: 540 PYECGVCAKKFMWRDSFMRHR 560
P+ CG C + F D + H+
Sbjct: 176 PFICGNCGRSFAQWDQLVAHK 196
Score = 41.6 bits (96), Expect = 0.002
Identities = 14/47 (29%), Positives = 24/47 (51%)
Query: 513 FDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH 559
+ C C + F+++ L H + HTG +P+ C C K F + + H
Sbjct: 375 YSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAH 421
Score = 35.4 bits (80), Expect = 0.16
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTH 535
G + + C C ++FS KS H H+ F C +C + F + L H K H
Sbjct: 511 GERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 32.7 bits (73), Expect = 1.0
Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 15/70 (21%)
Query: 512 PFDCPVCNKKFKMKHHLTEHMKTHTGLKP---YECGVCAKKFM-WRDSFMRHRGH----- 562
P CP C ++F+ L H + H P + C +C + F W + R H
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 563 ------CERR 566
CERR
Sbjct: 144 PIACPKCERR 153
>gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 87.4 bits (215), Expect = 4e-17
Identities = 53/166 (31%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 465 GVPGSVGGVPGGTGSGDGNKIFLCHC-GKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFK 523
G P PGG ++ F C C GK F HK H +H RP CP C K+F
Sbjct: 218 GRPAVTAPRPGGDAV---DRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFT 274
Query: 524 MKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGT--- 580
K +LT H + HTG KPY C C ++F + + + H +R G A PGPG+
Sbjct: 275 NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSE--GSAQAAPGPGSPQL 332
Query: 581 PTGPSLPSKRESPGVGGGSGDEASAATPPSSRR--VWSPPRVHKVE 624
P GP + +P V E PP + + +PP ++ +
Sbjct: 333 PAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCD 378
Score = 69.7 bits (169), Expect = 8e-12
Identities = 30/76 (39%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 486 FLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECG 544
F+C CGKAF HK H +H +P+ CP C K F K +L H + HTG +PY C
Sbjct: 459 FVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACP 518
Query: 545 VCAKKFMWRDSFMRHR 560
C + F + + + HR
Sbjct: 519 DCDRSFSQKSNLITHR 534
Score = 67.4 bits (163), Expect = 4e-11
Identities = 33/80 (41%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CG+ FS S H H RPF CP C K F+ K +L H + HTG KP
Sbjct: 427 GERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKP 486
Query: 541 YECGVCAKKFMWRDSFMRHR 560
Y C C K F + + + HR
Sbjct: 487 YVCPDCGKAFSQKSNLVSHR 506
Score = 60.5 bits (145), Expect = 5e-09
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K ++C CGKAFS KS H +H RP+ CP C++ F K +L H K+H
Sbjct: 483 GEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C +C + F + + H+
Sbjct: 543 FCCAICGQTFDDEERLLAHQ 562
Score = 58.5 bits (140), Expect = 2e-08
Identities = 24/71 (33%), Positives = 33/71 (46%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CG++F + H H RPF C C K F K HL H + H+G +P+ C C ++
Sbjct: 380 CGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRR 439
Query: 550 FMWRDSFMRHR 560
F HR
Sbjct: 440 FSQGSHLAAHR 450
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CGK F K+ H +H RPF C C ++F HL H + H +P
Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRP 458
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C K F + HR
Sbjct: 459 FVCPDCGKAFRHKPYLAAHR 478
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 486 FLCH-CGKAFSHKSMRDRHVNMHLNL-RPFDCPVCNKKFKMKHHLTEHMK----THTGLK 539
F CH CG++F H+ H RP CP C ++F + L H++ +
Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHPPAPEAR 175
Query: 540 PYECGVCAKKFMWRDSFMRHR 560
P+ CG C + F D + H+
Sbjct: 176 PFICGNCGRSFAQWDQLVAHK 196
Score = 41.6 bits (96), Expect = 0.002
Identities = 14/47 (29%), Positives = 24/47 (51%)
Query: 513 FDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH 559
+ C C + F+++ L H + HTG +P+ C C K F + + H
Sbjct: 375 YSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAH 421
Score = 35.4 bits (80), Expect = 0.16
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTH 535
G + + C C ++FS KS H H+ F C +C + F + L H K H
Sbjct: 511 GERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 32.7 bits (73), Expect = 1.0
Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 15/70 (21%)
Query: 512 PFDCPVCNKKFKMKHHLTEHMKTHTGLKP---YECGVCAKKFM-WRDSFMRHRGH----- 562
P CP C ++F+ L H + H P + C +C + F W + R H
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 563 ------CERR 566
CERR
Sbjct: 144 PIACPKCERR 153
>gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]
Length = 624
Score = 87.4 bits (215), Expect = 4e-17
Identities = 53/166 (31%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 465 GVPGSVGGVPGGTGSGDGNKIFLCHC-GKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFK 523
G P PGG ++ F C C GK F HK H +H RP CP C K+F
Sbjct: 275 GRPAVTAPRPGGDAV---DRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFT 331
Query: 524 MKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGT--- 580
K +LT H + HTG KPY C C ++F + + + H +R G A PGPG+
Sbjct: 332 NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSE--GSAQAAPGPGSPQL 389
Query: 581 PTGPSLPSKRESPGVGGGSGDEASAATPPSSRR--VWSPPRVHKVE 624
P GP + +P V E PP + + +PP ++ +
Sbjct: 390 PAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCD 435
Score = 69.7 bits (169), Expect = 8e-12
Identities = 30/76 (39%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 486 FLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECG 544
F+C CGKAF HK H +H +P+ CP C K F K +L H + HTG +PY C
Sbjct: 516 FVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACP 575
Query: 545 VCAKKFMWRDSFMRHR 560
C + F + + + HR
Sbjct: 576 DCDRSFSQKSNLITHR 591
Score = 67.4 bits (163), Expect = 4e-11
Identities = 33/80 (41%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CG+ FS S H H RPF CP C K F+ K +L H + HTG KP
Sbjct: 484 GERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKP 543
Query: 541 YECGVCAKKFMWRDSFMRHR 560
Y C C K F + + + HR
Sbjct: 544 YVCPDCGKAFSQKSNLVSHR 563
Score = 60.5 bits (145), Expect = 5e-09
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K ++C CGKAFS KS H +H RP+ CP C++ F K +L H K+H
Sbjct: 540 GEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 599
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C +C + F + + H+
Sbjct: 600 FCCAICGQTFDDEERLLAHQ 619
Score = 58.5 bits (140), Expect = 2e-08
Identities = 24/71 (33%), Positives = 33/71 (46%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CG++F + H H RPF C C K F K HL H + H+G +P+ C C ++
Sbjct: 437 CGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRR 496
Query: 550 FMWRDSFMRHR 560
F HR
Sbjct: 497 FSQGSHLAAHR 507
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CGK F K+ H +H RPF C C ++F HL H + H +P
Sbjct: 456 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRP 515
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C K F + HR
Sbjct: 516 FVCPDCGKAFRHKPYLAAHR 535
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 486 FLCH-CGKAFSHKSMRDRHVNMHLNL-RPFDCPVCNKKFKMKHHLTEHMK----THTGLK 539
F CH CG++F H+ H RP CP C ++F + L H++ +
Sbjct: 173 FACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHPPAPEAR 232
Query: 540 PYECGVCAKKFMWRDSFMRHR 560
P+ CG C + F D + H+
Sbjct: 233 PFICGNCGRSFAQWDQLVAHK 253
Score = 41.6 bits (96), Expect = 0.002
Identities = 14/47 (29%), Positives = 24/47 (51%)
Query: 513 FDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH 559
+ C C + F+++ L H + HTG +P+ C C K F + + H
Sbjct: 432 YSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAH 478
Score = 35.4 bits (80), Expect = 0.16
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTH 535
G + + C C ++FS KS H H+ F C +C + F + L H K H
Sbjct: 568 GERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 622
Score = 32.7 bits (73), Expect = 1.0
Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 15/70 (21%)
Query: 512 PFDCPVCNKKFKMKHHLTEHMKTHTGLKP---YECGVCAKKFM-WRDSFMRHRGH----- 562
P CP C ++F+ L H + H P + C +C + F W + R H
Sbjct: 141 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 200
Query: 563 ------CERR 566
CERR
Sbjct: 201 PIACPKCERR 210
>gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 87.4 bits (215), Expect = 4e-17
Identities = 53/166 (31%), Positives = 74/166 (44%), Gaps = 11/166 (6%)
Query: 465 GVPGSVGGVPGGTGSGDGNKIFLCHC-GKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFK 523
G P PGG ++ F C C GK F HK H +H RP CP C K+F
Sbjct: 218 GRPAVTAPRPGGDAV---DRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFT 274
Query: 524 MKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLGGVGAVPGPGT--- 580
K +LT H + HTG KPY C C ++F + + + H +R G A PGPG+
Sbjct: 275 NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSE--GSAQAAPGPGSPQL 332
Query: 581 PTGPSLPSKRESPGVGGGSGDEASAATPPSSRR--VWSPPRVHKVE 624
P GP + +P V E PP + + +PP ++ +
Sbjct: 333 PAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCD 378
Score = 69.7 bits (169), Expect = 8e-12
Identities = 30/76 (39%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 486 FLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECG 544
F+C CGKAF HK H +H +P+ CP C K F K +L H + HTG +PY C
Sbjct: 459 FVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACP 518
Query: 545 VCAKKFMWRDSFMRHR 560
C + F + + + HR
Sbjct: 519 DCDRSFSQKSNLITHR 534
Score = 67.4 bits (163), Expect = 4e-11
Identities = 33/80 (41%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CG+ FS S H H RPF CP C K F+ K +L H + HTG KP
Sbjct: 427 GERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKP 486
Query: 541 YECGVCAKKFMWRDSFMRHR 560
Y C C K F + + + HR
Sbjct: 487 YVCPDCGKAFSQKSNLVSHR 506
Score = 60.5 bits (145), Expect = 5e-09
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K ++C CGKAFS KS H +H RP+ CP C++ F K +L H K+H
Sbjct: 483 GEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C +C + F + + H+
Sbjct: 543 FCCAICGQTFDDEERLLAHQ 562
Score = 58.5 bits (140), Expect = 2e-08
Identities = 24/71 (33%), Positives = 33/71 (46%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CG++F + H H RPF C C K F K HL H + H+G +P+ C C ++
Sbjct: 380 CGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRR 439
Query: 550 FMWRDSFMRHR 560
F HR
Sbjct: 440 FSQGSHLAAHR 450
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CGK F K+ H +H RPF C C ++F HL H + H +P
Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRP 458
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C K F + HR
Sbjct: 459 FVCPDCGKAFRHKPYLAAHR 478
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 486 FLCH-CGKAFSHKSMRDRHVNMHLNL-RPFDCPVCNKKFKMKHHLTEHMK----THTGLK 539
F CH CG++F H+ H RP CP C ++F + L H++ +
Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHPPAPEAR 175
Query: 540 PYECGVCAKKFMWRDSFMRHR 560
P+ CG C + F D + H+
Sbjct: 176 PFICGNCGRSFAQWDQLVAHK 196
Score = 41.6 bits (96), Expect = 0.002
Identities = 14/47 (29%), Positives = 24/47 (51%)
Query: 513 FDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH 559
+ C C + F+++ L H + HTG +P+ C C K F + + H
Sbjct: 375 YSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAH 421
Score = 35.4 bits (80), Expect = 0.16
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 1/55 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTH 535
G + + C C ++FS KS H H+ F C +C + F + L H K H
Sbjct: 511 GERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 32.7 bits (73), Expect = 1.0
Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 15/70 (21%)
Query: 512 PFDCPVCNKKFKMKHHLTEHMKTHTGLKP---YECGVCAKKFM-WRDSFMRHRGH----- 562
P CP C ++F+ L H + H P + C +C + F W + R H
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 563 ------CERR 566
CERR
Sbjct: 144 PIACPKCERR 153
>gi|5730122 zinc finger and BTB domain containing 6 [Homo sapiens]
Length = 424
Score = 85.5 bits (210), Expect = 1e-16
Identities = 43/117 (36%), Positives = 63/117 (53%)
Query: 31 VVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKG 90
V+H F + +L+ +N R Q CDVSI + EF+ H+ +LAA S + DQ LL
Sbjct: 7 VLHFQFEQQGDVVLQKMNLLRQQNLFCDVSIYINDTEFQGHKVILAACSTFMRDQFLLTQ 66
Query: 91 MTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELL 147
+ + + +L S YTG L + +++ +LT S LQM HIV+KCTE L
Sbjct: 67 SKHVRITILQSAEVGRKLLLSCYTGALEVKRKELLKYLTAASYLQMVHIVEKCTEAL 123
Score = 75.1 bits (183), Expect = 2e-13
Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 1/78 (1%)
Query: 483 NKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPY 541
+K+FLC CGK F+ K +RH+ H+ +RPF C VC K F K L +H+ H+G +PY
Sbjct: 323 HKLFLCLQCGKTFTQKKNLNRHIRGHMGIRPFQCTVCLKTFTAKSTLQDHLNIHSGDRPY 382
Query: 542 ECGVCAKKFMWRDSFMRH 559
+C C F + + +H
Sbjct: 383 KCHCCDMDFKHKSALKKH 400
Score = 40.0 bits (92), Expect = 0.007
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTG 537
G + F C C K F+ KS H+N+H RP+ C C+ FK K L +H+ + G
Sbjct: 350 GIRPFQCTVCLKTFTAKSTLQDHLNIHSGDRPYKCHCCDMDFKHKSALKKHLTSVHG 406
Score = 32.0 bits (71), Expect = 1.8
Identities = 16/70 (22%), Positives = 26/70 (37%), Gaps = 25/70 (35%)
Query: 515 CPVCNK-------------------------KFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CP C + F K +L H++ H G++P++C VC K
Sbjct: 303 CPRCPRGFLHVENYLRHLKMHKLFLCLQCGKTFTQKKNLNRHIRGHMGIRPFQCTVCLKT 362
Query: 550 FMWRDSFMRH 559
F + + H
Sbjct: 363 FTAKSTLQDH 372
>gi|55925466 zinc finger protein 599 [Homo sapiens]
Length = 588
Score = 83.6 bits (205), Expect = 5e-16
Identities = 37/80 (46%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K++ C CGKAF+H+S +H H +PF C C K F + T+HM+ HTG KP
Sbjct: 335 GKKLYECGECGKAFTHRSTFIQHNVTHTGEKPFLCKECGKTFCLNSSFTQHMRIHTGEKP 394
Query: 541 YECGVCAKKFMWRDSFMRHR 560
YECG C K F R +F+RH+
Sbjct: 395 YECGECGKAFTHRSTFIRHK 414
Score = 78.6 bits (192), Expect = 2e-14
Identities = 36/79 (45%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C+ CGKA + + RH+ +H +P+ C C K FK + HLTEH + HTG KP
Sbjct: 223 GVKPYECNECGKACRYMADVIRHMRLHTGEKPYKCIECGKAFKRRFHLTEHQRIHTGDKP 282
Query: 541 YECGVCAKKFMWRDSFMRH 559
YEC C K F R SF++H
Sbjct: 283 YECKECGKAFTHRSSFIQH 301
Score = 78.2 bits (191), Expect = 2e-14
Identities = 36/79 (45%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C CGKAF+H+S RH H +PF+C C K F L +HM+ HTG KP
Sbjct: 391 GEKPYECGECGKAFTHRSTFIRHKRTHTGEKPFECKECGKAFCDSSSLIQHMRIHTGEKP 450
Query: 541 YECGVCAKKFMWRDSFMRH 559
YEC C K F F+RH
Sbjct: 451 YECSECGKAFTHHSVFIRH 469
Score = 78.2 bits (191), Expect = 2e-14
Identities = 36/80 (45%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K ++C CGKAF+ + RH +H +PF+C C K F LT+HM+THTG KP
Sbjct: 503 GEKPYVCRECGKAFTQPANFVRHNRIHTGEKPFECKECEKAFCDNFALTQHMRTHTGEKP 562
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+EC C K F SF HR
Sbjct: 563 FECNECGKTFSHSSSFTHHR 582
Score = 73.9 bits (180), Expect = 4e-13
Identities = 34/79 (43%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G+K + C CGKAF+H+S +H H +PF C C K F +HM+ HTG K
Sbjct: 279 GDKPYECKECGKAFTHRSSFIQHNMTHTREKPFLCKECGKAFYYSSSFAQHMRIHTGKKL 338
Query: 541 YECGVCAKKFMWRDSFMRH 559
YECG C K F R +F++H
Sbjct: 339 YECGECGKAFTHRSTFIQH 357
Score = 71.6 bits (174), Expect = 2e-12
Identities = 34/79 (43%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C CGKAF+H S+ RH H +P +C C K F T HM+ HTG KP
Sbjct: 447 GEKPYECSECGKAFTHHSVFIRHNRTHSGQKPLECKECAKAFYYSSSFTRHMRIHTGEKP 506
Query: 541 YECGVCAKKFMWRDSFMRH 559
Y C C K F +F+RH
Sbjct: 507 YVCRECGKAFTQPANFVRH 525
Score = 70.5 bits (171), Expect = 5e-12
Identities = 33/79 (41%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K F C CGKAF S +H+ +H +P++C C K F H +TH+G KP
Sbjct: 419 GEKPFECKECGKAFCDSSSLIQHMRIHTGEKPYECSECGKAFTHHSVFIRHNRTHSGQKP 478
Query: 541 YECGVCAKKFMWRDSFMRH 559
EC CAK F + SF RH
Sbjct: 479 LECKECAKAFYYSSSFTRH 497
Score = 68.6 bits (166), Expect = 2e-11
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K FLC CGK F S +H+ +H +P++C C K F + H +THTG KP
Sbjct: 363 GEKPFLCKECGKTFCLNSSFTQHMRIHTGEKPYECGECGKAFTHRSTFIRHKRTHTGEKP 422
Query: 541 YECGVCAKKFMWRDSFMRH 559
+EC C K F S ++H
Sbjct: 423 FECKECGKAFCDSSSLIQH 441
Score = 63.9 bits (154), Expect = 4e-10
Identities = 30/77 (38%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 484 KIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYE 542
K FLC CGKAF + S +H+ +H + ++C C K F + +H THTG KP+
Sbjct: 309 KPFLCKECGKAFYYSSSFAQHMRIHTGKKLYECGECGKAFTHRSTFIQHNVTHTGEKPFL 368
Query: 543 CGVCAKKFMWRDSFMRH 559
C C K F SF +H
Sbjct: 369 CKECGKTFCLNSSFTQH 385
Score = 62.8 bits (151), Expect = 9e-10
Identities = 29/79 (36%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 483 NKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPY 541
N + C CGK FS K RH +H ++P++C C K + + HM+ HTG KPY
Sbjct: 196 NNPYTCTECGKGFSKKWALVRHQQIHAGVKPYECNECGKACRYMADVIRHMRLHTGEKPY 255
Query: 542 ECGVCAKKFMWRDSFMRHR 560
+C C K F R H+
Sbjct: 256 KCIECGKAFKRRFHLTEHQ 274
Score = 62.4 bits (150), Expect = 1e-09
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C CGKAF + H +H +P++C C K F + +H THT KP
Sbjct: 251 GEKPYKCIECGKAFKRRFHLTEHQRIHTGDKPYECKECGKAFTHRSSFIQHNMTHTREKP 310
Query: 541 YECGVCAKKFMWRDSFMRH 559
+ C C K F + SF +H
Sbjct: 311 FLCKECGKAFYYSSSFAQH 329
Score = 58.9 bits (141), Expect = 1e-08
Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K C C KAF + S RH+ +H +P+ C C K F + H + HTG KP
Sbjct: 475 GQKPLECKECAKAFYYSSSFTRHMRIHTGEKPYVCRECGKAFTQPANFVRHNRIHTGEKP 534
Query: 541 YECGVCAKKFMWRDSFMRH 559
+EC C K F + +H
Sbjct: 535 FECKECEKAFCDNFALTQH 553
Score = 43.5 bits (101), Expect = 6e-04
Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 1/56 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHT 536
G K F C C KAF +H+ H +PF+C C K F T H K HT
Sbjct: 531 GEKPFECKECEKAFCDNFALTQHMRTHTGEKPFECNECGKTFSHSSSFTHHRKIHT 586
>gi|38348236 zinc finger protein 497 [Homo sapiens]
Length = 498
Score = 83.2 bits (204), Expect = 7e-16
Identities = 37/80 (46%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 482 GNKIFLCH-CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C CGKAF +S H H L+PF CP C K F L +H +THTG KP
Sbjct: 158 GEKPYACRECGKAFRAQSQLIHHQETHSGLKPFRCPDCGKSFGRSTTLVQHRRTHTGEKP 217
Query: 541 YECGVCAKKFMWRDSFMRHR 560
YEC C K F W +F+ HR
Sbjct: 218 YECPECGKAFSWNSNFLEHR 237
Score = 71.6 bits (174), Expect = 2e-12
Identities = 37/90 (41%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 479 SGDGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTG 537
S G + F C CGKAF S +H +H RPF C C+K F K L H +THTG
Sbjct: 407 SHTGERPFACAECGKAFRGSSELRQHQRLHSGERPFVCAHCSKAFVRKSELLSHRRTHTG 466
Query: 538 LKPYECGVCAKKFMWRDSFMRHRGHCERRH 567
+PY CG C K F R + H ++RH
Sbjct: 467 ERPYACGECGKPFSHRCNLNEH----QKRH 492
Score = 68.2 bits (165), Expect = 2e-11
Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C CGKAF+ S +H +H +P+ C C K F+ + L H +TH+GLKP
Sbjct: 130 GEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYACRECGKAFRAQSQLIHHQETHSGLKP 189
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C K F + ++HR
Sbjct: 190 FRCPDCGKSFGRSTTLVQHR 209
Score = 68.2 bits (165), Expect = 2e-11
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
Query: 470 VGGVPGGTGSGDGNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHL 528
V G+ + K F C CGKAF S +H H RPF+C C + F M +L
Sbjct: 286 VAGLRQHRRTHSSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAFVMGSYL 345
Query: 529 TEHMKTHTGLKPYECGVCAKKFMWRDSFMRHR 560
EH + HTG KP+ C C K R + + HR
Sbjct: 346 AEHRRVHTGEKPHACAQCGKASSQRSNLLSHR 377
Score = 65.9 bits (159), Expect = 1e-10
Identities = 27/71 (38%), Positives = 39/71 (54%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGKAFS S +H +H +P+ CP C K F +L++H + H+G KPY C C K
Sbjct: 111 CGKAFSQGSYLLQHRRVHTGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYACRECGKA 170
Query: 550 FMWRDSFMRHR 560
F + + H+
Sbjct: 171 FRAQSQLIHHQ 181
Score = 63.2 bits (152), Expect = 7e-10
Identities = 27/71 (38%), Positives = 36/71 (50%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGKAFS S H+ +H RP CP C K F L +H +TH+ KP+ C C K
Sbjct: 251 CGKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVRVAGLRQHRRTHSSEKPFPCAECGKA 310
Query: 550 FMWRDSFMRHR 560
F ++H+
Sbjct: 311 FRESSQLLQHQ 321
Score = 62.8 bits (151), Expect = 9e-10
Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C CGKAFS S H +H RP C C K F +L EH+K H G +P
Sbjct: 214 GEKPYECPECGKAFSWNSNFLEHRRVHTGARPHACRDCGKAFSQSSNLAEHLKIHAGARP 273
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C K F+ +HR
Sbjct: 274 HACPDCGKAFVRVAGLRQHR 293
Score = 62.8 bits (151), Expect = 9e-10
Identities = 30/80 (37%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K F C CGKAF S H H RPF C C K F+ L +H + H+G +P
Sbjct: 382 GAKPFACADCGKAFRGSSGLAHHRLSHTGERPFACAECGKAFRGSSELRQHQRLHSGERP 441
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C+K F+ + + HR
Sbjct: 442 FVCAHCSKAFVRKSELLSHR 461
Score = 62.4 bits (150), Expect = 1e-09
Identities = 27/79 (34%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K F C CGK+F + +H H +P++CP C K F + EH + HTG +P
Sbjct: 186 GLKPFRCPDCGKSFGRSTTLVQHRRTHTGEKPYECPECGKAFSWNSNFLEHRRVHTGARP 245
Query: 541 YECGVCAKKFMWRDSFMRH 559
+ C C K F + H
Sbjct: 246 HACRDCGKAFSQSSNLAEH 264
Score = 62.4 bits (150), Expect = 1e-09
Identities = 26/71 (36%), Positives = 37/71 (52%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGKAF + +H H + +PF C C K F+ L +H +THTG +P+EC C +
Sbjct: 279 CGKAFVRVAGLRQHRRTHSSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQA 338
Query: 550 FMWRDSFMRHR 560
F+ HR
Sbjct: 339 FVMGSYLAEHR 349
Score = 57.4 bits (137), Expect = 4e-08
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CG+AF S H +H +P C C K + +L H +TH+G KP
Sbjct: 326 GERPFECAECGQAFVMGSYLAEHRRVHTGEKPHACAQCGKASSQRSNLLSHRRTHSGAKP 385
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C K F HR
Sbjct: 386 FACADCGKAFRGSSGLAHHR 405
Score = 57.0 bits (136), Expect = 5e-08
Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K C CGKA S +S H H +PF C C K F+ L H +HTG +P
Sbjct: 354 GEKPHACAQCGKASSQRSNLLSHRRTHSGAKPFACADCGKAFRGSSGLAHHRLSHTGERP 413
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+ C C K F +H+
Sbjct: 414 FACAECGKAFRGSSELRQHQ 433
Score = 48.9 bits (115), Expect = 1e-05
Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTG 537
G + F+C HC KAF KS H H RP+ C C K F + +L EH K H G
Sbjct: 438 GERPFVCAHCSKAFVRKSELLSHRRTHTGERPYACGECGKPFSHRCNLNEHQKRHGG 494
Score = 48.5 bits (114), Expect = 2e-05
Identities = 18/46 (39%), Positives = 24/46 (52%)
Query: 515 CPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHR 560
C C K F +L +H + HTG KPY C C K F W + +H+
Sbjct: 108 CGECGKAFSQGSYLLQHRRVHTGEKPYTCPECGKAFAWSSNLSQHQ 153
>gi|33859678 zinc finger protein 416 [Homo sapiens]
Length = 594
Score = 82.4 bits (202), Expect = 1e-15
Identities = 35/76 (46%), Positives = 47/76 (61%), Gaps = 1/76 (1%)
Query: 486 FLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECG 544
++C CGKAF KS RH H RPF+C C K F+ + L EH K HTGL+PY+CG
Sbjct: 466 YVCGECGKAFMFKSKLVRHQRTHTGERPFECSECGKFFRQSYTLVEHQKIHTGLRPYDCG 525
Query: 545 VCAKKFMWRDSFMRHR 560
C K F+ + S ++H+
Sbjct: 526 QCGKSFIQKSSLIQHQ 541
Score = 73.2 bits (178), Expect = 7e-13
Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + ++C CGK+FS ++ +H +H RP++C C K F +L EH + HTG +P
Sbjct: 294 GERPYVCGQCGKSFSQRATLIKHHRVHTGERPYECGECGKSFSQSSNLIEHCRIHTGERP 353
Query: 541 YECGVCAKKFMWRDSFMRHR 560
YEC C K F + + +RH+
Sbjct: 354 YECDECGKAFGSKSTLVRHQ 373
Score = 72.8 bits (177), Expect = 9e-13
Identities = 34/80 (42%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + + C CGK+FS S H +H RP++C C K F K L H +THTG KP
Sbjct: 322 GERPYECGECGKSFSQSSNLIEHCRIHTGERPYECDECGKAFGSKSTLVRHQRTHTGEKP 381
Query: 541 YECGVCAKKFMWRDSFMRHR 560
YECG C K F S + H+
Sbjct: 382 YECGECGKLFRQSFSLVVHQ 401
Score = 72.0 bits (175), Expect = 2e-12
Identities = 36/89 (40%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CGK F H +H LRP+DC C K F K L +H HTG +P
Sbjct: 490 GERPFECSECGKFFRQSYTLVEHQKIHTGLRPYDCGQCGKSFIQKSSLIQHQVVHTGERP 549
Query: 541 YECGVCAKKFMWRDSFMRHR-GHCERRHR 568
YECG C K F + HR H R R
Sbjct: 550 YECGKCGKSFTQHSGLILHRKSHTVERPR 578
Score = 71.2 bits (173), Expect = 3e-12
Identities = 30/71 (42%), Positives = 41/71 (57%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGK+FS K +H +H RPF+C C K F + L +H K HT +PY CG C K
Sbjct: 415 CGKSFSLKCGLIQHQLIHSGARPFECDECGKSFSQRTTLNKHHKVHTAERPYVCGECGKA 474
Query: 550 FMWRDSFMRHR 560
FM++ +RH+
Sbjct: 475 FMFKSKLVRHQ 485
Score = 68.9 bits (167), Expect = 1e-11
Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + + C CGKAF KS RH H +P++C C K F+ L H + HT +P
Sbjct: 350 GERPYECDECGKAFGSKSTLVRHQRTHTGEKPYECGECGKLFRQSFSLVVHQRIHTTARP 409
Query: 541 YECGVCAKKFMWRDSFMRHR 560
YECG C K F + ++H+
Sbjct: 410 YECGQCGKSFSLKCGLIQHQ 429
Score = 67.8 bits (164), Expect = 3e-11
Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + + C CGK+FS S + H +H RP+ C C K F + L +H + HTG +P
Sbjct: 266 GERPYECSECGKSFSQTSHLNDHRRIHTGERPYVCGQCGKSFSQRATLIKHHRVHTGERP 325
Query: 541 YECGVCAKKFMWRDSFMRH 559
YECG C K F + + H
Sbjct: 326 YECGECGKSFSQSSNLIEH 344
Score = 67.4 bits (163), Expect = 4e-11
Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + F C CGK+FS ++ ++H +H RP+ C C K F K L H +THTG +P
Sbjct: 434 GARPFECDECGKSFSQRTTLNKHHKVHTAERPYVCGECGKAFMFKSKLVRHQRTHTGERP 493
Query: 541 YECGVCAKKFMWRDSFMRHR 560
+EC C K F + + H+
Sbjct: 494 FECSECGKFFRQSYTLVEHQ 513
Score = 63.2 bits (152), Expect = 7e-10
Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGKA + + +H RP++C C K F HL +H + HTG +PY CG C K
Sbjct: 247 CGKACCCECSLVQLQRVHPGERPYECSECGKSFSQTSHLNDHRRIHTGERPYVCGQCGKS 306
Query: 550 FMWRDSFMR-HRGHC-ERRHRLGGVG 573
F R + ++ HR H ER + G G
Sbjct: 307 FSQRATLIKHHRVHTGERPYECGECG 332
Score = 63.2 bits (152), Expect = 7e-10
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C CGK F H +H RP++C C K F +K L +H H+G +P
Sbjct: 378 GEKPYECGECGKLFRQSFSLVVHQRIHTTARPYECGQCGKSFSLKCGLIQHQLIHSGARP 437
Query: 541 YECGVCAKKFMWRDSFMRH 559
+EC C K F R + +H
Sbjct: 438 FECDECGKSFSQRTTLNKH 456
Score = 50.1 bits (118), Expect = 6e-06
Identities = 23/68 (33%), Positives = 34/68 (50%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGK+F KS +H +H RP++C C K F L H K+HT +P + C K
Sbjct: 527 CGKSFIQKSSLIQHQVVHTGERPYECGKCGKSFTQHSGLILHRKSHTVERPRDSSKCGKP 586
Query: 550 FMWRDSFM 557
+ R + +
Sbjct: 587 YSPRSNIV 594
Score = 34.7 bits (78), Expect = 0.28
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 1/71 (1%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
C + SHK H + R ++ C K + L + + H G +PYEC C K
Sbjct: 220 CRRESSHKHTFF-HPRVCTGKRLYESSKCGKACCCECSLVQLQRVHPGERPYECSECGKS 278
Query: 550 FMWRDSFMRHR 560
F HR
Sbjct: 279 FSQTSHLNDHR 289
>gi|13376460 zinc finger protein 556 [Homo sapiens]
Length = 456
Score = 82.4 bits (202), Expect = 1e-15
Identities = 38/79 (48%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K++ C CGKAFS S H H +P+ C C K F H LTEH++THTG KP
Sbjct: 171 GQKLYKCKECGKAFSRPSYLQTHEKTHSGEKPYACQSCGKTFLRSHSLTEHVRTHTGEKP 230
Query: 541 YECGVCAKKFMWRDSFMRH 559
YECG C K F SF H
Sbjct: 231 YECGQCGKGFSCPKSFRAH 249
Score = 78.2 bits (191), Expect = 2e-14
Identities = 48/147 (32%), Positives = 69/147 (46%), Gaps = 4/147 (2%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G K + C CGK FS HV MH RP++C C K F+ + HM H G +P
Sbjct: 227 GEKPYECGQCGKGFSCPKSFRAHVMMHAGGRPYECKHCGKAFRCQKSFRVHMIMHAGGRP 286
Query: 541 YECGVCAKKFMWRDSFMRH-RGH-CERRHRLGGVGAVPG-PGTPTGPSLPSKRESPGVGG 597
YEC C K + W SF RH R H E+ ++ G G G P + + ++ P GG
Sbjct: 287 YECKQCGKAYCWATSFQRHVRIHNGEKPYKCGKCGKAFGWPSSLHKHARTHAKKKPVSGG 346
Query: 598 GSGDEASAATPPSSRRVWSPPRVHKVE 624
G ++ P + + + +V+K E
Sbjct: 347 SVGKSSARPRPSTDVKSQTREKVYKCE 373
Score = 63.2 bits (152), Expect = 7e-10
Identities = 33/86 (38%), Positives = 41/86 (47%), Gaps = 2/86 (2%)
Query: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKK 549
CGK F+H S RH H + + C C K F +L H KTH+G KPY C C K
Sbjct: 152 CGKLFTHSSSLIRHKRAHSGQKLYKCKECGKAFSRPSYLQTHEKTHSGEKPYACQSCGKT 211
Query: 550 FMWRDSFMRH-RGHC-ERRHRLGGVG 573
F+ S H R H E+ + G G
Sbjct: 212 FLRSHSLTEHVRTHTGEKPYECGQCG 237
Score = 53.5 bits (127), Expect = 6e-07
Identities = 37/143 (25%), Positives = 52/143 (36%), Gaps = 32/143 (22%)
Query: 482 GNKIFLC-HCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKP 540
G + + C CGKA+ + RHV +H +P+ C C K F L +H +TH KP
Sbjct: 283 GGRPYECKQCGKAYCWATSFQRHVRIHNGEKPYKCGKCGKAFGWPSSLHKHARTHAKKKP 342
Query: 541 ---------------------------YECGVCAKKFMWRDSFMRHRGHCERRHRLGGVG 573
Y+C C K + W S +H ER+H
Sbjct: 343 VSGGSVGKSSARPRPSTDVKSQTREKVYKCETCGKTYGWSSSLHKH----ERKHTGEKPV 398
Query: 574 AVPGPGTPTGPSLPSKRESPGVG 596
G P+G SK +G
Sbjct: 399 NAASVGKPSGGLCSSKNVRTQIG 421
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 479 SGDGNKIFLCHCGKAFSHKSMRDRHV--NMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHT 536
S GNK G+ F +RH+ N ++R ++C C K F L H + H+
Sbjct: 116 SSKGNKR-----GRTFRKTRNCNRHLRKNCCTSVRRYECSQCGKLFTHSSSLIRHKRAHS 170
Query: 537 GLKPYECGVCAKKFMWRDSFMR 558
G K Y+C C K F R S+++
Sbjct: 171 GQKLYKCKECGKAFS-RPSYLQ 191
Score = 34.7 bits (78), Expect = 0.28
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 12/82 (14%)
Query: 491 GKAFSHKSMRDRHVNMHLNL-------RPFDCPVCNKK---FKMKHHLTEHMKTH--TGL 538
GK + S++D+H +L RP NK+ F+ + H++ + T +
Sbjct: 85 GKNWEEHSVKDKHNTKERHLSRNPRVERPCKSSKGNKRGRTFRKTRNCNRHLRKNCCTSV 144
Query: 539 KPYECGVCAKKFMWRDSFMRHR 560
+ YEC C K F S +RH+
Sbjct: 145 RRYECSQCGKLFTHSSSLIRHK 166
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,057,563
Number of Sequences: 37866
Number of extensions: 2124715
Number of successful extensions: 30333
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1186
Number of HSP's successfully gapped in prelim test: 553
Number of HSP's that attempted gapping in prelim test: 13638
Number of HSP's gapped (non-prelim): 14861
length of query: 634
length of database: 18,247,518
effective HSP length: 108
effective length of query: 526
effective length of database: 14,157,990
effective search space: 7447102740
effective search space used: 7447102740
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.