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Search of human proteins with 223646111
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223646111 family with sequence similarity 157, member B
[Homo sapiens]
(384 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223646111 family with sequence similarity 157, member B [Homo... 800 0.0
gi|239743047 PREDICTED: similar to family with sequence similari... 786 0.0
gi|239745655 PREDICTED: family with sequence similarity 157, mem... 770 0.0
gi|223646109 family with sequence similarity 157, member A [Homo... 769 0.0
gi|169169586 PREDICTED: hypothetical protein [Homo sapiens] 42 7e-04
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 41 0.002
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 41 0.002
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 41 0.002
gi|110347429 mediator complex subunit 12 [Homo sapiens] 41 0.002
gi|55956910 meningioma 1 [Homo sapiens] 41 0.002
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 40 0.003
gi|56118214 zinc finger protein 161 [Homo sapiens] 40 0.005
gi|38158015 mastermind-like 3 [Homo sapiens] 40 0.005
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 39 0.008
gi|33286444 mastermind-like 2 [Homo sapiens] 39 0.010
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 38 0.018
gi|187171277 DNA-directed DNA polymerase gamma [Homo sapiens] 37 0.023
gi|4505937 DNA-directed DNA polymerase gamma [Homo sapiens] 37 0.023
gi|4507379 TATA box binding protein [Homo sapiens] 37 0.023
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 37 0.023
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 37 0.030
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 37 0.030
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 37 0.030
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 37 0.030
gi|90403598 mesoderm posterior 2 homolog [Homo sapiens] 37 0.030
gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo ... 37 0.039
gi|40354197 THAP domain containing 11 [Homo sapiens] 37 0.039
gi|120952764 mastermind-like domain containing 1 [Homo sapiens] 37 0.039
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 36 0.051
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 36 0.067
>gi|223646111 family with sequence similarity 157, member B [Homo
sapiens]
Length = 384
Score = 800 bits (2067), Expect = 0.0
Identities = 384/384 (100%), Positives = 384/384 (100%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 120
KPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF
Sbjct: 61 KPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 120
Query: 121 RFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFATKRIWIHRRGEATA 180
RFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFATKRIWIHRRGEATA
Sbjct: 121 RFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFATKRIWIHRRGEATA 180
Query: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 240
RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT
Sbjct: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 240
Query: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ
Sbjct: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
Query: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF
Sbjct: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
Query: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
FIDSPTVIAVPDLQCPTKYSGILY
Sbjct: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
>gi|239743047 PREDICTED: similar to family with sequence similarity
157, member B [Homo sapiens]
Length = 384
Score = 786 bits (2030), Expect = 0.0
Identities = 378/384 (98%), Positives = 380/384 (98%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 120
KPSEDIYKNR+RR+QQQQQQQQQQQLDLLFHQRIQISLWP KQKRRKTEQHSHPFVKKAF
Sbjct: 61 KPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQHSHPFVKKAF 120
Query: 121 RFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFATKRIWIHRRGEATA 180
RFSAGPGC RPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFA KRIWIHRRGEATA
Sbjct: 121 RFSAGPGCGRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 180
Query: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 240
RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYA GAVIPTGT
Sbjct: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIPTGT 240
Query: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ
Sbjct: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
Query: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF
Sbjct: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
Query: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
FIDSPTVIAVPDLQCPTKYSGILY
Sbjct: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
>gi|239745655 PREDICTED: family with sequence similarity 157, member
C [Homo sapiens]
Length = 387
Score = 770 bits (1988), Expect = 0.0
Identities = 373/387 (96%), Positives = 377/387 (97%), Gaps = 3/387 (0%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGN+TMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNATMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKN---RQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVK 117
KPSEDIYKN +Q++QQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSH FVK
Sbjct: 61 KPSEDIYKNWRRQQQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHSFVK 120
Query: 118 KAFRFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFATKRIWIHRRGE 177
KAFRFSA PGC RPSSNKMLRSMGGGQRP GLGSEFFRLLHDLHLLAF TK IWIHRRGE
Sbjct: 121 KAFRFSASPGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFPTKCIWIHRRGE 180
Query: 178 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP 237
ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP
Sbjct: 181 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP 240
Query: 238 TGTPERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK 297
TGTPERAQPPPPQD LGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK
Sbjct: 241 TGTPERAQPPPPQDLLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK 300
Query: 298 VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVN 357
VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVN
Sbjct: 301 VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVN 360
Query: 358 LVFFIDSPTVIAVPDLQCPTKYSGILY 384
LVFFIDSPTVIAVPDLQCPTKYSGILY
Sbjct: 361 LVFFIDSPTVIAVPDLQCPTKYSGILY 387
>gi|223646109 family with sequence similarity 157, member A [Homo
sapiens]
Length = 383
Score = 769 bits (1985), Expect = 0.0
Identities = 372/384 (96%), Positives = 375/384 (97%), Gaps = 1/384 (0%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 120
KPSEDIYKN Q+ QQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF
Sbjct: 61 KPSEDIYKNWQQ-QQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 119
Query: 121 RFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFATKRIWIHRRGEATA 180
RFSAG GC RPSSNKMLRSMGGGQRP GLGSEFFRLLHDLHLLAFA KRIWIHRRGEATA
Sbjct: 120 RFSAGSGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 179
Query: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 240
RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT
Sbjct: 180 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 239
Query: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ
Sbjct: 240 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 299
Query: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPL+CQKQRGAS SSGQH GRVNLVF
Sbjct: 300 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLRCQKQRGASASSGQHEGRVNLVF 359
Query: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
FI SPTVIAVPDLQCPTKYSG+LY
Sbjct: 360 FIGSPTVIAVPDLQCPTKYSGMLY 383
>gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]
Length = 251
Score = 42.4 bits (98), Expect = 7e-04
Identities = 41/116 (35%), Positives = 47/116 (40%), Gaps = 15/116 (12%)
Query: 178 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP 237
A P A HPA PA +RG A RR + T G P R GG +
Sbjct: 62 AVPSPPAAAHPARPA--LRGETPAPG---RRGRATTRGEVQPSVRPPLSHRPLRGGGM-G 115
Query: 238 TGTPERAQPP------PPQDPLGRRRWLSRNTWGPWPGTT--QPPSPQLLR-NDWG 284
G P + PP PP P GRR WLS GP G + SP + R DWG
Sbjct: 116 RGRPGKGPPPNPSRRLPPAPPGGRRTWLSALATGPAAGGAGRRRRSPPVFRAADWG 171
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 7/72 (9%)
Query: 50 LSRQVKEVAAQKPSEDIYKNRQRR-------QQQQQQQQQQQQLDLLFHQRIQISLWPRK 102
L +Q + Q+ ++ YK +Q + QQQQQQQQQQQQ Q+ Q ++
Sbjct: 122 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 181
Query: 103 QKRRKTEQHSHP 114
Q++++ +Q HP
Sbjct: 182 QQQQQQQQQQHP 193
Score = 38.5 bits (88), Expect = 0.010
Identities = 20/55 (36%), Positives = 32/55 (58%)
Query: 56 EVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 110
++ Q+ + + +Q++QQQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 149 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 203
Score = 32.0 bits (71), Expect = 0.96
Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQ--QLDLLFHQRI 94
+Q ++ Q+ + + +Q ++QQQQQQQQQQ L+F Q++
Sbjct: 177 QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 221
Score = 29.6 bits (65), Expect = 4.8
Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQ--------QQQQQQQLDLLFHQRIQISLWPRKQ 103
+Q ++ Q+ + + +Q++QQQQQ QQQQQQQ L Q++ +
Sbjct: 165 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 224
Query: 104 KRRKTEQH 111
++ + +QH
Sbjct: 225 QQLQQQQH 232
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 7/72 (9%)
Query: 50 LSRQVKEVAAQKPSEDIYKNRQRR-------QQQQQQQQQQQQLDLLFHQRIQISLWPRK 102
L +Q + Q+ ++ YK +Q + QQQQQQQQQQQQ Q+ Q ++
Sbjct: 30 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 89
Query: 103 QKRRKTEQHSHP 114
Q++++ +Q HP
Sbjct: 90 QQQQQQQQQQHP 101
Score = 38.5 bits (88), Expect = 0.010
Identities = 20/55 (36%), Positives = 32/55 (58%)
Query: 56 EVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 110
++ Q+ + + +Q++QQQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 57 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 111
Score = 32.0 bits (71), Expect = 0.96
Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQ--QLDLLFHQRI 94
+Q ++ Q+ + + +Q ++QQQQQQQQQQ L+F Q++
Sbjct: 85 QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 129
Score = 29.6 bits (65), Expect = 4.8
Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQ--------QQQQQQQLDLLFHQRIQISLWPRKQ 103
+Q ++ Q+ + + +Q++QQQQQ QQQQQQQ L Q++ +
Sbjct: 73 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 132
Query: 104 KRRKTEQH 111
++ + +QH
Sbjct: 133 QQLQQQQH 140
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 7/72 (9%)
Query: 50 LSRQVKEVAAQKPSEDIYKNRQRR-------QQQQQQQQQQQQLDLLFHQRIQISLWPRK 102
L +Q + Q+ ++ YK +Q + QQQQQQQQQQQQ Q+ Q ++
Sbjct: 147 LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 206
Query: 103 QKRRKTEQHSHP 114
Q++++ +Q HP
Sbjct: 207 QQQQQQQQQQHP 218
Score = 38.5 bits (88), Expect = 0.010
Identities = 20/55 (36%), Positives = 32/55 (58%)
Query: 56 EVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 110
++ Q+ + + +Q++QQQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 174 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 228
Score = 32.0 bits (71), Expect = 0.96
Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQ--QLDLLFHQRI 94
+Q ++ Q+ + + +Q ++QQQQQQQQQQ L+F Q++
Sbjct: 202 QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
Score = 29.6 bits (65), Expect = 4.8
Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQ--------QQQQQQQLDLLFHQRIQISLWPRKQ 103
+Q ++ Q+ + + +Q++QQQQQ QQQQQQQ L Q++ +
Sbjct: 190 QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 249
Query: 104 KRRKTEQH 111
++ + +QH
Sbjct: 250 QQLQQQQH 257
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/77 (33%), Positives = 40/77 (51%)
Query: 34 LGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQR 93
L + MI PMS + A P + + +Q++QQQQQQQQQQQQ +H R
Sbjct: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080
Query: 94 IQISLWPRKQKRRKTEQ 110
Q +Q++++ +Q
Sbjct: 2081 QQQQQQILRQQQQQQQQ 2097
Score = 35.4 bits (80), Expect = 0.087
Identities = 15/26 (57%), Positives = 21/26 (80%)
Query: 60 QKPSEDIYKNRQRRQQQQQQQQQQQQ 85
Q+ + I + +Q++QQQQQQQQQQQQ
Sbjct: 2081 QQQQQQILRQQQQQQQQQQQQQQQQQ 2106
Score = 35.4 bits (80), Expect = 0.087
Identities = 15/34 (44%), Positives = 25/34 (73%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
+Q +++ Q+ + + +Q++QQQQQQQQQQQQ
Sbjct: 2082 QQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQ 2115
Score = 34.7 bits (78), Expect = 0.15
Identities = 22/94 (23%), Positives = 46/94 (48%)
Query: 48 VPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRK 107
+P +Q ++ Q+ + + +Q++QQQ +QQQQQ L Q+ Q ++Q++++
Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQ 2107
Query: 108 TEQHSHPFVKKAFRFSAGPGCRRPSSNKMLRSMG 141
+Q ++ + A P +P S + G
Sbjct: 2108 QQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
Score = 30.4 bits (67), Expect = 2.8
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 40 IRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQ 84
IR + +Q ++ Q+ + + +Q++QQQ QQQQQQQ
Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQ 2123
Score = 28.9 bits (63), Expect = 8.1
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 34 LGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
L ++ H P+ + ++AQ + +QQQQQQQQQQQ
Sbjct: 2010 LTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQ 2061
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 40.8 bits (94), Expect = 0.002
Identities = 71/278 (25%), Positives = 98/278 (35%), Gaps = 59/278 (21%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQK 104
P S P ++ A S + +Q++QQQQQQQQQQQQ QR +L ++
Sbjct: 503 PDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMA 562
Query: 105 RRKTEQH---------SHP-FVKKAFRFSAGP--GCRRPSSNKMLRSMGGGQRPMGLGSE 152
R +Q HP V + GP G +P+ + S G G+ LG+
Sbjct: 563 SRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGR----LGTF 618
Query: 153 FFRLLHDLHLLAFATKRIWI------------HRRG----EATARPRAPEHPAPPATAVR 196
+ H A + W R G A P P PP
Sbjct: 619 EQQAPH------LAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGS 672
Query: 197 G--RDAASQNLKRRPGSG------TDGLRLQGAEPS-RLLRTYAGGAVIPTGTPERAQPP 247
G Q R PG G + GL+ G+ L++ G +P+ ER PP
Sbjct: 673 GVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPP 732
Query: 248 P----------PQDPLGRRRWLSRNTWGPWPGTTQPPS 275
P P P G ++T PG PPS
Sbjct: 733 PDFATSALGGQPGFPFGAAG--RQSTPHSGPGVNSPPS 768
Score = 28.9 bits (63), Expect = 8.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Query: 70 RQRRQQQQQQQQQQQQLDLLFHQ 92
+Q+ QQQQQ QQQQQQ + F +
Sbjct: 294 QQQPQQQQQPQQQQQQHGVFFER 316
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQH 111
+Q ++ Q+ + + + +Q++QQQ QQQQQQQQ+ LL R +S P++Q++++
Sbjct: 3941 QQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLS--PQQQQQQQVALG 3998
Query: 112 SHPFVKKAFRFSAGPGCRRPS 132
K FS+ PG P+
Sbjct: 3999 PGMPAKPLQHFSS-PGALGPT 4018
Score = 38.1 bits (87), Expect = 0.013
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 17/100 (17%)
Query: 11 AHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNR 70
+HSG PK +PM Q L + Q ++ Q+ + + + +
Sbjct: 3882 SHSGQ----PKLSAQPMGSLQQLQQQQQL-------------QQQQQLQQQQQQQLQQQQ 3924
Query: 71 QRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 110
Q +QQQ QQQQQQQQL Q++Q +Q++++ +Q
Sbjct: 3925 QLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQ 3964
Score = 35.8 bits (81), Expect = 0.067
Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 10 GAHSGPMRPL-PKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDI-- 66
G H + L K+ A R+ ++ ++ + +Q+ +V Q+
Sbjct: 3533 GVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLM 3592
Query: 67 --YKNRQRRQQQQQQQQQQQQLDLL 89
Y+N+Q++QQQQQQQQQQQ +L
Sbjct: 3593 AEYRNKQQQQQQQQQQQQQQHSAVL 3617
Score = 31.6 bits (70), Expect = 1.3
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 35 GNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRI 94
G+ + H + S Q K A S + +Q+ QQQQQ QQQQQQ L Q++
Sbjct: 3868 GSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQ-QLQQQQQL 3926
Query: 95 QISLWPRKQKRRKTEQ 110
Q ++Q++++ +Q
Sbjct: 3927 QQQQLQQQQQQQQLQQ 3942
Score = 30.8 bits (68), Expect = 2.1
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 70 RQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPF 115
+Q++Q QQQQ QQQQQ L Q+ Q ++Q +++ +Q F
Sbjct: 3921 QQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQF 3966
Score = 29.6 bits (65), Expect = 4.8
Identities = 17/54 (31%), Positives = 29/54 (53%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKR 105
+Q+++ Q+ + + + ++QQQQ QQQQQQQ Q+ Q + Q R
Sbjct: 3929 QQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSR 3982
Score = 29.3 bits (64), Expect = 6.2
Identities = 18/47 (38%), Positives = 27/47 (57%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQ 95
P SR ++E Q + + ++ +QQQQQQQQQQ L + Q+ Q
Sbjct: 3711 PDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQ 3757
>gi|56118214 zinc finger protein 161 [Homo sapiens]
Length = 521
Score = 39.7 bits (91), Expect = 0.005
Identities = 20/41 (48%), Positives = 27/41 (65%), Gaps = 6/41 (14%)
Query: 63 SEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQ 103
SE+ +Q++QQQQQQQQQQQQ Q+ ++ WP KQ
Sbjct: 329 SEETSNQKQQQQQQQQQQQQQQQ------QQQHVTSWPGKQ 363
Score = 37.4 bits (85), Expect = 0.023
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 42 HTCPMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPR 101
+TC + + +E + QK + +Q++QQQQQQQQQQ Q + LW
Sbjct: 317 NTCKQGISKTCMSEETSNQKQQQQ----QQQQQQQQQQQQQQHVTSWPGKQVETLRLWEE 372
Query: 102 KQKRRKTE 109
K RK E
Sbjct: 373 AVKARKKE 380
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 39.7 bits (91), Expect = 0.005
Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 21/110 (19%)
Query: 45 PMSVPLS-----RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLW 99
P++VP S Q+K++AAQ+ ++++QQQQQQQQQQQQ
Sbjct: 454 PVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQ-------------- 499
Query: 100 PRKQKRRKTEQHSH--PFVKKAFRFSAGPGCRRPSSNKMLRSMGGGQRPM 147
++Q+++ + Q S+ P + + A +P+S M Q P+
Sbjct: 500 QQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPI 549
Score = 33.9 bits (76), Expect = 0.25
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 18/120 (15%)
Query: 32 LLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDI--YKNRQRRQQQQQQQQQQQQLDLL 89
L GN+ + H + LS+++ A + Y +Q++QQQQQQQQQQQQ
Sbjct: 593 LTYGNTKPLTH---FNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQ---- 645
Query: 90 FHQRIQISLWPRKQKRRKTEQHSHPFVKKAFRFSAGPGCRRPSSNKMLRSMGGGQRPMGL 149
P + + H K+ +P + L S G Q P+GL
Sbjct: 646 ---------QPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
Score = 33.5 bits (75), Expect = 0.33
Identities = 23/80 (28%), Positives = 48/80 (60%), Gaps = 4/80 (5%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRR 106
S P + +K++ + ++ I + +Q+ ++Q+QQQQQQQ +L Q++Q S PR +
Sbjct: 728 SQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQ-QILAEQQLQQSHLPR--QHL 784
Query: 107 KTEQHSHPFVKKAFRFSAGP 126
+ +++ +P V++ +F P
Sbjct: 785 QPQRNPYP-VQQVNQFQGSP 803
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 38.9 bits (89), Expect = 0.008
Identities = 24/64 (37%), Positives = 36/64 (56%), Gaps = 4/64 (6%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKT 108
P R + +A P + +Q++QQQQQQQQQQQQ Q+ Q PR+Q++++
Sbjct: 37 PGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQ----QQQQQQETSPRQQQQQQG 92
Query: 109 EQHS 112
E S
Sbjct: 93 EDGS 96
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 38.5 bits (88), Expect = 0.010
Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 4/70 (5%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQ----ISLWP 100
P + ++Q ++ Q+ + + +Q++QQQQQQQQQQQQ + Q+ Q IS
Sbjct: 581 PSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQ 640
Query: 101 RKQKRRKTEQ 110
++Q++++ +Q
Sbjct: 641 QQQQQQQQQQ 650
Score = 37.4 bits (85), Expect = 0.023
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ------LDLLFHQRIQISLWPRKQKR 105
+Q ++AQ+ + + +Q++QQQQQQQQQQQQ L Q + S P +QK
Sbjct: 631 QQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKL 690
Query: 106 RKTEQHSHPFVKKAFRFS 123
+ + P ++ S
Sbjct: 691 LLQQMQNQPIAGMGYQVS 708
Score = 35.4 bits (80), Expect = 0.087
Identities = 17/25 (68%), Positives = 20/25 (80%)
Query: 61 KPSEDIYKNRQRRQQQQQQQQQQQQ 85
KPS Y +Q++QQQQQQQQQQQQ
Sbjct: 580 KPSLLHYTQQQQQQQQQQQQQQQQQ 604
Score = 34.7 bits (78), Expect = 0.15
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 17/101 (16%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQH 111
+Q ++AQ+ + ++QQQQQQQQQQQQ ++Q++++ +Q
Sbjct: 619 QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQ---------------QQQQQQQQQQQ 663
Query: 112 SHPFVKKAFRFSAGPGCRR--PSSNKMLRSMGGGQRPMGLG 150
P + A + P R P K+L Q G+G
Sbjct: 664 QQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMG 704
Score = 34.3 bits (77), Expect = 0.19
Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Query: 36 NSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQ 95
NS P +P + + + + + +Q++QQQQQQQQQQQQ Q+ Q
Sbjct: 563 NSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-QQQQQ 621
Query: 96 ISLWPRKQKRRKT 108
S+ ++Q+++++
Sbjct: 622 SSISAQQQQQQQS 634
Score = 33.5 bits (75), Expect = 0.33
Identities = 15/39 (38%), Positives = 26/39 (66%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
S+ +Q ++ ++ + + +Q++QQQQQQQQQQQQ
Sbjct: 623 SISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQ 661
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 37.7 bits (86), Expect = 0.018
Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 12/99 (12%)
Query: 179 TARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAV-IP 237
T RP AP P P V G ++ PGSG+ G P L R G ++ P
Sbjct: 565 TKRP-APARPTMPPPQVSGSRSSPPAPPLPPGSGSPGT------PQALPRRLVGSSLRAP 617
Query: 238 TGTPERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSP 276
T P P PP P RR R+ P P + P SP
Sbjct: 618 TVPP----PLPPTPPQPARRQSRRSPASPSPASPGPASP 652
>gi|187171277 DNA-directed DNA polymerase gamma [Homo sapiens]
Length = 1239
Score = 37.4 bits (85), Expect = 0.023
Identities = 18/37 (48%), Positives = 25/37 (67%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
P+ + V++ P+ D ++RRQQQQQQQQQQQQ
Sbjct: 18 PVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQ 54
Score = 35.8 bits (81), Expect = 0.067
Identities = 19/45 (42%), Positives = 26/45 (57%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLL 89
P+ P V A PS+ + +Q++QQQQQQQQQ QQ +L
Sbjct: 18 PVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVL 62
>gi|4505937 DNA-directed DNA polymerase gamma [Homo sapiens]
Length = 1239
Score = 37.4 bits (85), Expect = 0.023
Identities = 18/37 (48%), Positives = 25/37 (67%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
P+ + V++ P+ D ++RRQQQQQQQQQQQQ
Sbjct: 18 PVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQ 54
Score = 35.8 bits (81), Expect = 0.067
Identities = 19/45 (42%), Positives = 26/45 (57%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLL 89
P+ P V A PS+ + +Q++QQQQQQQQQ QQ +L
Sbjct: 18 PVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVL 62
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 37.4 bits (85), Expect = 0.023
Identities = 20/48 (41%), Positives = 31/48 (64%)
Query: 63 SEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 110
S I + +QR+QQQQQQQQQQQQ Q+ Q ++Q++++ +Q
Sbjct: 48 SLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 95
Score = 37.0 bits (84), Expect = 0.030
Identities = 18/46 (39%), Positives = 31/46 (67%)
Query: 40 IRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
I++T +S+ +Q ++ Q+ + + +Q++QQQQQQQQQQQQ
Sbjct: 43 IQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 88
Score = 35.4 bits (80), Expect = 0.087
Identities = 18/42 (42%), Positives = 28/42 (66%)
Query: 71 QRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHS 112
Q+RQQQQQQQQQQQQ Q+ Q ++Q++++ +Q +
Sbjct: 55 QQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQA 96
Score = 35.0 bits (79), Expect = 0.11
Identities = 16/34 (47%), Positives = 24/34 (70%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
RQ ++ Q+ + + +Q++QQQQQQQQQQQQ
Sbjct: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 90
Score = 33.9 bits (76), Expect = 0.25
Identities = 17/46 (36%), Positives = 28/46 (60%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQIS 97
+Q ++ Q+ + + +Q++QQQQQQQQQQQQ + +Q S
Sbjct: 60 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQS 105
Score = 33.5 bits (75), Expect = 0.33
Identities = 15/34 (44%), Positives = 24/34 (70%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
+Q ++ Q+ + + +Q++QQQQQQQQQQQQ
Sbjct: 58 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 91
Score = 33.5 bits (75), Expect = 0.33
Identities = 15/34 (44%), Positives = 24/34 (70%)
Query: 52 RQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
+Q ++ Q+ + + +Q++QQQQQQQQQQQQ
Sbjct: 59 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 92
Score = 33.1 bits (74), Expect = 0.43
Identities = 15/41 (36%), Positives = 25/41 (60%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
P + + + + Q+ + + +Q++QQQQQQQQQQQQ
Sbjct: 40 PQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQ 80
Score = 32.7 bits (73), Expect = 0.56
Identities = 16/41 (39%), Positives = 25/41 (60%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
P+ S + E ++ + + +Q++QQQQQQQQQQQQ
Sbjct: 42 PIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQ 82
Score = 31.2 bits (69), Expect = 1.6
Identities = 18/65 (27%), Positives = 33/65 (50%)
Query: 71 QRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAFRFSAGPGCRR 130
+ +Q+QQQQQQQQQQ Q+ Q ++Q++++ +Q A + S +
Sbjct: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
Query: 131 PSSNK 135
+S +
Sbjct: 113 GTSGQ 117
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 37.4 bits (85), Expect = 0.023
Identities = 19/45 (42%), Positives = 26/45 (57%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQR 93
P Q V+ + + +N ++QQQQQQQQQQQQL HQ+
Sbjct: 510 PAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQ 554
Score = 32.0 bits (71), Expect = 0.96
Identities = 48/237 (20%), Positives = 86/237 (36%), Gaps = 16/237 (6%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQK 104
P + P +Q AQ Q +QQ +QQQQQQ Q+ + + ++Q
Sbjct: 436 PQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQA 495
Query: 105 RRKTEQHSHPFVKKAFRFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLA 164
+ + Q HP ++ + S +++++ Q+ + +L LH
Sbjct: 496 QTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQ 555
Query: 165 FATKRIWIHRRGE-ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEP 223
T++ + ++ A + P+ A P A A ++++P ++Q P
Sbjct: 556 LMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQP-------KVQTTPP 608
Query: 224 SRLLRTYAGGAVIPTGTPERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLR 280
+ G P+ P G RR LS T G S QLL+
Sbjct: 609 PAVQGQKVGSLTPPSS--------PKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQ 657
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 37.0 bits (84), Expect = 0.030
Identities = 43/152 (28%), Positives = 62/152 (40%), Gaps = 25/152 (16%)
Query: 2 GPLFTTIPGAHSGPMR-PLPKKHVEPMAVRQLLLGNSTMIR-----HTCPMSVPLSRQVK 55
G L P A S P R P P V+ +R +L + R T ++V R +
Sbjct: 154 GALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLP 213
Query: 56 EVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPF 115
+ Q+ + + +Q++QQQQQQQ QQQ P+ Q T+Q P
Sbjct: 214 GLQQQQQQQQQQQQQQQQQQQQQQQPQQQP--------------PQPQ----TQQQQQPA 255
Query: 116 VKKAFRFSA-GPGCRRPSSNKMLRSMGGGQRP 146
+ R S GP PS+ + L G RP
Sbjct: 256 LVNYNRPSGPGPELSGPSTPQKLPVPAPGGRP 287
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 37.0 bits (84), Expect = 0.030
Identities = 43/152 (28%), Positives = 62/152 (40%), Gaps = 25/152 (16%)
Query: 2 GPLFTTIPGAHSGPMR-PLPKKHVEPMAVRQLLLGNSTMIR-----HTCPMSVPLSRQVK 55
G L P A S P R P P V+ +R +L + R T ++V R +
Sbjct: 154 GALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLP 213
Query: 56 EVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPF 115
+ Q+ + + +Q++QQQQQQQ QQQ P+ Q T+Q P
Sbjct: 214 GLQQQQQQQQQQQQQQQQQQQQQQQPQQQP--------------PQPQ----TQQQQQPA 255
Query: 116 VKKAFRFSA-GPGCRRPSSNKMLRSMGGGQRP 146
+ R S GP PS+ + L G RP
Sbjct: 256 LVNYNRPSGPGPELSGPSTPQKLPVPAPGGRP 287
>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
sapiens]
Length = 443
Score = 37.0 bits (84), Expect = 0.030
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 8/104 (7%)
Query: 58 AAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVK 117
A Q+ + + +Q++QQQQQQQQQQQ+ L H P + H P +
Sbjct: 123 ALQQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMG 182
Query: 118 KAFRFSAGPGCRRPS--SNKMLRSMGGGQRPMGLGSEFFRLLHD 159
+ + G +PS N ML G G +P GL R HD
Sbjct: 183 AS---NGGLLYSQPSFTVNGML---GAGGQPAGLHHHGLRDAHD 220
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 37.0 bits (84), Expect = 0.030
Identities = 21/57 (36%), Positives = 30/57 (52%)
Query: 71 QRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAFRFSAGPG 127
Q++QQQQQQQQQQQQ Q+ Q+ P +Q +++ Q P + PG
Sbjct: 261 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPG 317
Score = 35.4 bits (80), Expect = 0.087
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 6 TTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMS-VPLSRQVKEVAAQKPSE 64
T P + S M PL + + ++Q + ++ PM V ++RQ+ + +
Sbjct: 207 TPRPASQSDAMDPL----LSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQ 262
Query: 65 DIYKNRQRRQQQQQQQQQQQQLDL 88
+ +Q++QQQQQQQQQQQQ L
Sbjct: 263 QQQQQQQQQQQQQQQQQQQQQQQL 286
Score = 32.7 bits (73), Expect = 0.56
Identities = 18/40 (45%), Positives = 24/40 (60%)
Query: 71 QRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 110
Q +QQQQQQQQQQQQ Q+ Q L R ++ + +Q
Sbjct: 259 QLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQ 298
Score = 32.7 bits (73), Expect = 0.56
Identities = 28/106 (26%), Positives = 41/106 (38%), Gaps = 20/106 (18%)
Query: 9 PGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYK 68
PG S P+ P + + P +++H P P +Q + Q+
Sbjct: 971 PGYPSQPVEQRPLQQMPPQ-----------LMQHVAPPPQPPQQQPQPQLPQQQQPP--P 1017
Query: 69 NRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHP 114
Q + QQQQQQQQQ + L+ Q K R Q+ HP
Sbjct: 1018 PSQPQSQQQQQQQQQMMMMLMMQQ-------DPKSVRLPVSQNVHP 1056
>gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]
Length = 397
Score = 37.0 bits (84), Expect = 0.030
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 1/43 (2%)
Query: 244 AQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSC 286
AQ PPPQ LG W+ WG W G SP + GSC
Sbjct: 2 AQSPPPQSLLGHDHWIFAQGWG-WAGHWDSTSPASSSDSSGSC 43
>gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo
sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.039
Identities = 18/51 (35%), Positives = 22/51 (43%)
Query: 173 HRRGEATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEP 223
H +G RP P APP G + + NL+R PG G L G P
Sbjct: 523 HGQGVDLTRPSRPRLSAPPDITAFGEEGETDNLRRHPGVGPRSAHLGGLVP 573
Score = 29.3 bits (64), Expect = 6.2
Identities = 31/103 (30%), Positives = 35/103 (33%), Gaps = 25/103 (24%)
Query: 269 GTTQPPSPQLLRNDWGSCGFMVPEA---ARGKVFQDSQ-----------EGAHIRRETVS 314
G P P R WG G + P ARGK SQ R T
Sbjct: 195 GARPRPGPTSSRRPWGRAGGLRPRGKRPARGKKRPSSQRRCSSPSAARASATSAPRPTAP 254
Query: 315 KSVCAEP--WRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGR 355
SV A+P R QR R P C + G + G HG R
Sbjct: 255 SSV-AQPSSARSQRRRAP--------CPHRAGGADGVGSHGAR 288
>gi|40354197 THAP domain containing 11 [Homo sapiens]
Length = 314
Score = 36.6 bits (83), Expect = 0.039
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 11/75 (14%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQK 104
P PL + A++P+ R+++QQQQQQQQQQQQ Q+ Q ++Q+
Sbjct: 77 PTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQ------QQQQ-----QQQQ 125
Query: 105 RRKTEQHSHPFVKKA 119
+++ +Q S P A
Sbjct: 126 QQQQQQQSSPSASTA 140
>gi|120952764 mastermind-like domain containing 1 [Homo sapiens]
Length = 774
Score = 36.6 bits (83), Expect = 0.039
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 24/90 (26%)
Query: 2 GPLFTTIPGAHSGPMRPL-PKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
G L + +P ++ GP P P+K P +Q ++IR P S LS
Sbjct: 441 GHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLIRSLTPTSNLLS--------- 491
Query: 61 KPSEDIYKNRQRRQQQQQQQQQQQQLDLLF 90
QQQQQQQQQQQ +++F
Sbjct: 492 --------------QQQQQQQQQQQANVIF 507
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 36.2 bits (82), Expect = 0.051
Identities = 17/28 (60%), Positives = 22/28 (78%)
Query: 58 AAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
A +K D+ +RQ++QQQQQQQQQQQQ
Sbjct: 1710 ANRKKLADMIASRQQQQQQQQQQQQQQQ 1737
Score = 35.4 bits (80), Expect = 0.087
Identities = 17/31 (54%), Positives = 23/31 (74%)
Query: 55 KEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQ 85
KE +K ++ I +Q++QQQQQQQQQQQQ
Sbjct: 1708 KEANRKKLADMIASRQQQQQQQQQQQQQQQQ 1738
Score = 33.9 bits (76), Expect = 0.25
Identities = 15/29 (51%), Positives = 21/29 (72%)
Query: 68 KNRQRRQQQQQQQQQQQQLDLLFHQRIQI 96
+ +Q++QQQQQQQQQQQQ L + Q+
Sbjct: 1724 QQQQQQQQQQQQQQQQQQAQTLAQAQAQV 1752
Score = 33.1 bits (74), Expect = 0.43
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Query: 34 LGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQR 93
LGN P S P K++A S + +Q++QQQQQQQQQQ Q +
Sbjct: 1693 LGNPIGANIASP-SEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQ 1751
Query: 94 IQISLWPRKQKR 105
+Q L Q++
Sbjct: 1752 VQAHLQQELQQQ 1763
Score = 28.9 bits (63), Expect = 8.1
Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 6/55 (10%)
Query: 62 PSEDIYKNRQR------RQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 110
PSE NR++ +QQQQQQQQQQQ Q+ Q + Q + +Q
Sbjct: 1704 PSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQ 1758
Score = 28.9 bits (63), Expect = 8.1
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 60 QKPSEDIYKNRQRRQQQQQQQQQQQQ 85
Q E I + +QR+ QQQQQQ+ QQQ
Sbjct: 3369 QSLQEAIQQQQQRQLQQQQQQKVQQQ 3394
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 35.8 bits (81), Expect = 0.067
Identities = 19/52 (36%), Positives = 27/52 (51%)
Query: 63 SEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHP 114
S +Y +Q++QQQQQQQQQQQQ +R + ++ HS P
Sbjct: 1455 SNHLYIKQQQQQQQQQQQQQQQQQAGQLRERHHLYQMQHHVPHAESSVHSQP 1506
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,557,929
Number of Sequences: 37866
Number of extensions: 1058291
Number of successful extensions: 10825
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 268
Number of HSP's that attempted gapping in prelim test: 6939
Number of HSP's gapped (non-prelim): 2109
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.