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Search of human proteins with 223646109
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223646109 family with sequence similarity 157, member A
[Homo sapiens]
(383 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223646109 family with sequence similarity 157, member A [Homo... 800 0.0
gi|223646111 family with sequence similarity 157, member B [Homo... 769 0.0
gi|239743047 PREDICTED: similar to family with sequence similari... 765 0.0
gi|239745655 PREDICTED: family with sequence similarity 157, mem... 764 0.0
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 44 3e-04
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 44 3e-04
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 44 3e-04
gi|169169586 PREDICTED: hypothetical protein [Homo sapiens] 42 7e-04
gi|38158015 mastermind-like 3 [Homo sapiens] 41 0.002
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 39 0.006
gi|110347429 mediator complex subunit 12 [Homo sapiens] 39 0.006
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 38 0.013
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 38 0.013
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 38 0.013
gi|56118214 zinc finger protein 161 [Homo sapiens] 38 0.013
gi|33286444 mastermind-like 2 [Homo sapiens] 38 0.017
gi|55956910 meningioma 1 [Homo sapiens] 38 0.017
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 38 0.017
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 37 0.023
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 37 0.023
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 37 0.023
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 37 0.023
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 37 0.023
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 37 0.023
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 37 0.023
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 37 0.023
gi|4507379 TATA box binding protein [Homo sapiens] 37 0.030
gi|120952764 mastermind-like domain containing 1 [Homo sapiens] 37 0.030
gi|90403598 mesoderm posterior 2 homolog [Homo sapiens] 37 0.030
gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo ... 37 0.039
>gi|223646109 family with sequence similarity 157, member A [Homo
sapiens]
Length = 383
Score = 800 bits (2065), Expect = 0.0
Identities = 383/383 (100%), Positives = 383/383 (100%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAFR 120
KPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAFR
Sbjct: 61 KPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAFR 120
Query: 121 FSAGSGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATAR 180
FSAGSGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATAR
Sbjct: 121 FSAGSGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATAR 180
Query: 181 PRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGTP 240
PRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGTP
Sbjct: 181 PRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGTP 240
Query: 241 ERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQD 300
ERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQD
Sbjct: 241 ERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQD 300
Query: 301 SQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLRCQKQRGASASSGQHEGRVNLVFF 360
SQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLRCQKQRGASASSGQHEGRVNLVFF
Sbjct: 301 SQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLRCQKQRGASASSGQHEGRVNLVFF 360
Query: 361 IGSPTVIAVPDLQCPTKYSGMLY 383
IGSPTVIAVPDLQCPTKYSGMLY
Sbjct: 361 IGSPTVIAVPDLQCPTKYSGMLY 383
>gi|223646111 family with sequence similarity 157, member B [Homo
sapiens]
Length = 384
Score = 769 bits (1985), Expect = 0.0
Identities = 372/384 (96%), Positives = 375/384 (97%), Gaps = 1/384 (0%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNWQQ-QQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 119
KPSEDIYKN Q+ QQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF
Sbjct: 61 KPSEDIYKNRQRRQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 120
Query: 120 RFSAGSGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 179
RFSAG GC RPSSNKMLRSMGGGQRP GLGSEFFRLLHDLHLLAFA KRIWIHRRGEATA
Sbjct: 121 RFSAGPGCRRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFATKRIWIHRRGEATA 180
Query: 180 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 239
RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT
Sbjct: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 240
Query: 240 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 299
PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ
Sbjct: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
Query: 300 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLRCQKQRGASASSGQHEGRVNLVF 359
DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPL+CQKQRGAS SSGQH GRVNLVF
Sbjct: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
Query: 360 FIGSPTVIAVPDLQCPTKYSGMLY 383
FI SPTVIAVPDLQCPTKYSG+LY
Sbjct: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
>gi|239743047 PREDICTED: similar to family with sequence similarity
157, member B [Homo sapiens]
Length = 384
Score = 765 bits (1975), Expect = 0.0
Identities = 370/384 (96%), Positives = 375/384 (97%), Gaps = 1/384 (0%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNWQQQ-QQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAF 119
KPSEDIYKN +++ QQQQQQQQQQQLDLLFHQRIQISLWP KQKRRKTEQHSHPFVKKAF
Sbjct: 61 KPSEDIYKNRRRRRQQQQQQQQQQQLDLLFHQRIQISLWPCKQKRRKTEQHSHPFVKKAF 120
Query: 120 RFSAGSGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 179
RFSAG GCGRPSSNKMLRSMGGGQRP GLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA
Sbjct: 121 RFSAGPGCGRPSSNKMLRSMGGGQRPMGLGSEFFRLLHDLHLLAFAMKRIWIHRRGEATA 180
Query: 180 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIPTGT 239
RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYA GAVIPTGT
Sbjct: 181 RPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYARGAVIPTGT 240
Query: 240 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 299
PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ
Sbjct: 241 PERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGKVFQ 300
Query: 300 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLRCQKQRGASASSGQHEGRVNLVF 359
DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPL+CQKQRGAS SSGQH GRVNLVF
Sbjct: 301 DSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVNLVF 360
Query: 360 FIGSPTVIAVPDLQCPTKYSGMLY 383
FI SPTVIAVPDLQCPTKYSG+LY
Sbjct: 361 FIDSPTVIAVPDLQCPTKYSGILY 384
>gi|239745655 PREDICTED: family with sequence similarity 157, member
C [Homo sapiens]
Length = 387
Score = 764 bits (1974), Expect = 0.0
Identities = 370/387 (95%), Positives = 373/387 (96%), Gaps = 4/387 (1%)
Query: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGN+TMIRHTCPMSVPLSRQVKEVAAQ
Sbjct: 1 MGPLFTTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNATMIRHTCPMSVPLSRQVKEVAAQ 60
Query: 61 KPSEDIYKNW----QQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVK 116
KPSEDIYKNW QQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSH FVK
Sbjct: 61 KPSEDIYKNWRRQQQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHSFVK 120
Query: 117 KAFRFSAGSGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFAMKRIWIHRRGE 176
KAFRFSA GCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAF K IWIHRRGE
Sbjct: 121 KAFRFSASPGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLLHDLHLLAFPTKCIWIHRRGE 180
Query: 177 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP 236
ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP
Sbjct: 181 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP 240
Query: 237 TGTPERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK 296
TGTPERAQPPPPQD LGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK
Sbjct: 241 TGTPERAQPPPPQDLLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSCGFMVPEAARGK 300
Query: 297 VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLRCQKQRGASASSGQHEGRVN 356
VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPL+CQKQRGAS SSGQH GRVN
Sbjct: 301 VFQDSQEGAHIRRETVSKSVCAEPWRHQRARDPAPTNFPLKCQKQRGASTSSGQHGGRVN 360
Query: 357 LVFFIGSPTVIAVPDLQCPTKYSGMLY 383
LVFFI SPTVIAVPDLQCPTKYSG+LY
Sbjct: 361 LVFFIDSPTVIAVPDLQCPTKYSGILY 387
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 43.5 bits (101), Expect = 3e-04
Identities = 24/67 (35%), Positives = 38/67 (56%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRK 106
+V L +Q + +K E ++ QQQQQQQQQQQQQ Q+ Q ++Q++++
Sbjct: 127 AVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 186
Query: 107 TEQHSHP 113
+Q HP
Sbjct: 187 QQQQQHP 193
Score = 38.1 bits (87), Expect = 0.013
Identities = 21/50 (42%), Positives = 28/50 (56%)
Query: 60 QKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
Q+ + + QQQQQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 154 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 203
Score = 32.0 bits (71), Expect = 0.96
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQL---DLLFHQRI 93
+Q ++ Q+ + + Q ++QQQQQQQQQQL L+F Q++
Sbjct: 177 QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 221
Score = 29.6 bits (65), Expect = 4.8
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQ--------QQQQQQQLDLLFHQRIQISLWPRKQK 103
+Q ++ Q+ + + QQQQQQQ QQQQQQQ L Q++ + +
Sbjct: 166 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 225
Query: 104 RRKTEQH 110
+ + +QH
Sbjct: 226 QLQQQQH 232
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 43.5 bits (101), Expect = 3e-04
Identities = 24/67 (35%), Positives = 38/67 (56%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRK 106
+V L +Q + +K E ++ QQQQQQQQQQQQQ Q+ Q ++Q++++
Sbjct: 35 AVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 94
Query: 107 TEQHSHP 113
+Q HP
Sbjct: 95 QQQQQHP 101
Score = 38.1 bits (87), Expect = 0.013
Identities = 21/50 (42%), Positives = 28/50 (56%)
Query: 60 QKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
Q+ + + QQQQQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 62 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 111
Score = 32.0 bits (71), Expect = 0.96
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQL---DLLFHQRI 93
+Q ++ Q+ + + Q ++QQQQQQQQQQL L+F Q++
Sbjct: 85 QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 129
Score = 29.6 bits (65), Expect = 4.8
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQ--------QQQQQQQLDLLFHQRIQISLWPRKQK 103
+Q ++ Q+ + + QQQQQQQ QQQQQQQ L Q++ + +
Sbjct: 74 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 133
Query: 104 RRKTEQH 110
+ + +QH
Sbjct: 134 QLQQQQH 140
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 43.5 bits (101), Expect = 3e-04
Identities = 24/67 (35%), Positives = 38/67 (56%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRK 106
+V L +Q + +K E ++ QQQQQQQQQQQQQ Q+ Q ++Q++++
Sbjct: 152 AVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 211
Query: 107 TEQHSHP 113
+Q HP
Sbjct: 212 QQQQQHP 218
Score = 38.1 bits (87), Expect = 0.013
Identities = 21/50 (42%), Positives = 28/50 (56%)
Query: 60 QKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
Q+ + + QQQQQQQQQQQQQQ Q+ Q P KQ + + +Q
Sbjct: 179 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQ 228
Score = 32.0 bits (71), Expect = 0.96
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQL---DLLFHQRI 93
+Q ++ Q+ + + Q ++QQQQQQQQQQL L+F Q++
Sbjct: 202 QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246
Score = 29.6 bits (65), Expect = 4.8
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQ--------QQQQQQQLDLLFHQRIQISLWPRKQK 103
+Q ++ Q+ + + QQQQQQQ QQQQQQQ L Q++ + +
Sbjct: 191 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQ 250
Query: 104 RRKTEQH 110
+ + +QH
Sbjct: 251 QLQQQQH 257
>gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]
Length = 251
Score = 42.4 bits (98), Expect = 7e-04
Identities = 41/116 (35%), Positives = 47/116 (40%), Gaps = 15/116 (12%)
Query: 177 ATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAVIP 236
A P A HPA PA +RG A RR + T G P R GG +
Sbjct: 62 AVPSPPAAAHPARPA--LRGETPAPG---RRGRATTRGEVQPSVRPPLSHRPLRGGGM-G 115
Query: 237 TGTPERAQPP------PPQDPLGRRRWLSRNTWGPWPGTT--QPPSPQLLR-NDWG 283
G P + PP PP P GRR WLS GP G + SP + R DWG
Sbjct: 116 RGRPGKGPPPNPSRRLPPAPPGGRRTWLSALATGPAAGGAGRRRRSPPVFRAADWG 171
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 28/112 (25%)
Query: 45 PMSVPLS-----RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWP 99
P++VP S Q+K++AAQ+ +QQQQQQQQQQQQQ
Sbjct: 454 PVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQ--------------- 498
Query: 100 RKQKRRKTEQHSH------PFVKKAFRFSAGSGCGRPSSNKMLRSMGGGQRP 145
Q++++ +QHS+ P + + A +P+S M Q P
Sbjct: 499 --QQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNP 548
Score = 36.6 bits (83), Expect = 0.039
Identities = 34/117 (29%), Positives = 47/117 (40%), Gaps = 13/117 (11%)
Query: 32 LLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQ 91
L GN+ + H + LS+++ A + QQQQQQQQQQQQQQ Q
Sbjct: 593 LTYGNTKPLTH---FNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQ------Q 643
Query: 92 RIQISLWPRKQKRRKTEQHSHPFVKKAFRFSAGSGCGRPSSNKMLRSMGGGQRPTGL 148
+ Q P + + H K+ +P + L S G Q P GL
Sbjct: 644 QQQ----PPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL 696
Score = 34.3 bits (77), Expect = 0.19
Identities = 19/55 (34%), Positives = 34/55 (61%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRK 101
S P + +K++ + ++ I + QQ ++Q+QQQQQQ +L Q++Q S PR+
Sbjct: 728 SQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHLPRQ 782
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 39.3 bits (90), Expect = 0.006
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTE 108
P R + +A P + QQQQQQQQQQQQQQ Q+ Q PR+Q++++ E
Sbjct: 37 PGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQ---QQQQQQETSPRQQQQQQGE 93
Query: 109 QHS 111
S
Sbjct: 94 DGS 96
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 39.3 bits (90), Expect = 0.006
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 34 LGNSTMIRHTCPMSVP-LSRQVKEVAA----QKPSEDIYKNWQQQQQQQQQQQQQQLDLL 88
L + MI PMS + V+ A Q+ + + QQQQQQQQQQQQQQ +
Sbjct: 2021 LQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIR 2080
Query: 89 FHQRIQISLWPRKQKRRKTEQ 109
Q+ QI ++Q++++ +Q
Sbjct: 2081 QQQQQQILRQQQQQQQQQQQQ 2101
Score = 35.4 bits (80), Expect = 0.087
Identities = 16/25 (64%), Positives = 19/25 (76%)
Query: 60 QKPSEDIYKNWQQQQQQQQQQQQQQ 84
Q+ + I + QQQQQQQQQQQQQQ
Sbjct: 2081 QQQQQQILRQQQQQQQQQQQQQQQQ 2105
Score = 35.4 bits (80), Expect = 0.087
Identities = 16/33 (48%), Positives = 23/33 (69%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
+Q +++ Q+ + + QQQQQQQQQQQQQQ
Sbjct: 2082 QQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQ 2114
Score = 34.3 bits (77), Expect = 0.19
Identities = 20/57 (35%), Positives = 31/57 (54%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTE 108
RQ ++ + + + QQQQQQQQQQQQQQ Q+ Q + P+ Q + + +
Sbjct: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQ 2136
Score = 33.9 bits (76), Expect = 0.25
Identities = 16/33 (48%), Positives = 22/33 (66%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
+Q + Q+ + + + QQQQQQQQQQQQQQ
Sbjct: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ 2106
Score = 33.5 bits (75), Expect = 0.33
Identities = 18/62 (29%), Positives = 35/62 (56%)
Query: 48 VPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKT 107
+P +Q ++ Q+ + + QQQQQQ +QQQQ +L Q+ Q ++Q++++
Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQ 2107
Query: 108 EQ 109
+Q
Sbjct: 2108 QQ 2109
Score = 33.5 bits (75), Expect = 0.33
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQ---QQQQQQQQLDLLFHQRIQISLWPRKQKRRKTE 108
+Q ++ Q+ + Y QQQQQQ QQQQQQQQ Q+ Q ++Q +++ +
Sbjct: 2062 QQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121
Query: 109 QHSHP 113
Q + P
Sbjct: 2122 QQAAP 2126
Score = 32.7 bits (73), Expect = 0.56
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 50 LSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
L +Q ++ Q+ + + QQQQQQQ QQQQQQ
Sbjct: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQ 2122
Score = 32.3 bits (72), Expect = 0.73
Identities = 17/45 (37%), Positives = 24/45 (53%)
Query: 40 IRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
IR + +Q ++ Q+ + + QQQQQQ QQQQQQQ
Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQ 2123
Score = 32.3 bits (72), Expect = 0.73
Identities = 18/39 (46%), Positives = 22/39 (56%)
Query: 71 QQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
QQQQQQQQQQQQQQ Q+ Q P + + + Q
Sbjct: 2098 QQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQ 2136
Score = 30.0 bits (66), Expect = 3.6
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 4/84 (4%)
Query: 26 PMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQL 85
PM+ + + G +R T + +Q ++ Q+ + + QQQQ +QQQQQQ+
Sbjct: 2032 PMSAQGVQAG----VRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQI 2087
Query: 86 DLLFHQRIQISLWPRKQKRRKTEQ 109
Q+ Q ++Q++++ +Q
Sbjct: 2088 LRQQQQQQQQQQQQQQQQQQQQQQ 2111
Score = 29.6 bits (65), Expect = 4.8
Identities = 21/89 (23%), Positives = 41/89 (46%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHS 111
+Q ++ Q+ + + QQQQQ +QQQQQ L Q+ Q ++Q++++ +Q
Sbjct: 2053 QQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQ 2112
Query: 112 HPFVKKAFRFSAGSGCGRPSSNKMLRSMG 140
++ + A +P S + G
Sbjct: 2113 QQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 38.1 bits (87), Expect = 0.013
Identities = 22/56 (39%), Positives = 37/56 (66%), Gaps = 3/56 (5%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQ-QQQQQQQQLDLLFHQRIQISLWPRKQKRRK 106
+Q ++ Q+ + + + QQQQQQ QQQQQQQQ+ LL R +S P++Q++++
Sbjct: 3941 QQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLS--PQQQQQQQ 3994
Score = 36.6 bits (83), Expect = 0.039
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 5/80 (6%)
Query: 10 GAHSGPMRPL-PKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDI-- 66
G H + L K+ A R+ ++ ++ + +Q+ +V Q+
Sbjct: 3533 GVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLM 3592
Query: 67 --YKNWQQQQQQQQQQQQQQ 84
Y+N QQQQQQQQQQQQQQ
Sbjct: 3593 AEYRNKQQQQQQQQQQQQQQ 3612
Score = 35.0 bits (79), Expect = 0.11
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 16/99 (16%)
Query: 11 AHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNW 70
+HSG PK +PM Q L + +Q +++ Q+ + +
Sbjct: 3882 SHSGQ----PKLSAQPMGSLQQLQQQQQL------------QQQQQLQQQQQQQLQQQQQ 3925
Query: 71 QQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
QQQQ QQQQQQQQL Q++Q +Q++++ +Q
Sbjct: 3926 LQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQ 3964
Score = 33.9 bits (76), Expect = 0.25
Identities = 24/75 (32%), Positives = 37/75 (49%)
Query: 35 GNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQ 94
G+ + H + S Q K A S + QQ QQQQQ QQQQQ L Q++Q
Sbjct: 3868 GSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQ 3927
Query: 95 ISLWPRKQKRRKTEQ 109
++Q++++ +Q
Sbjct: 3928 QQQLQQQQQQQQLQQ 3942
Score = 31.6 bits (70), Expect = 1.3
Identities = 18/44 (40%), Positives = 25/44 (56%)
Query: 71 QQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPF 114
QQQ QQQQ QQQQQ L Q+ Q ++Q +++ +Q F
Sbjct: 3923 QQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQF 3966
Score = 31.6 bits (70), Expect = 1.3
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQ 94
+Q+++ Q+ + + QQQQQQ QQQQQQ F Q+ Q
Sbjct: 3929 QQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ 3971
Score = 30.0 bits (66), Expect = 3.6
Identities = 17/37 (45%), Positives = 22/37 (59%)
Query: 49 PLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQL 85
P SR ++E Q + + + QQQQQQQQQQQ L
Sbjct: 3711 PDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHL 3747
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 38.1 bits (87), Expect = 0.013
Identities = 30/80 (37%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Query: 71 QQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAFRFSAGSGCGRP 130
QQQQQQQQQQQQQQ Q+ Q+ P +Q +++ Q P +F+A + P
Sbjct: 262 QQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRP------QFTAPTQVPVP 315
Query: 131 SSNKMLRSMGGGQRPTGLGS 150
L S G Q P GS
Sbjct: 316 PGWNQLPS-GALQPPPAQGS 334
Score = 34.7 bits (78), Expect = 0.15
Identities = 28/84 (33%), Positives = 42/84 (50%), Gaps = 8/84 (9%)
Query: 6 TTIPGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMS-VPLSRQVKEV---AAQK 61
T P + S M PL + + ++Q + ++ PM V ++RQ+ Q+
Sbjct: 207 TPRPASQSDAMDPL----LSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQ 262
Query: 62 PSEDIYKNWQQQQQQQQQQQQQQL 85
+ + QQQQQQQQQQQQQQL
Sbjct: 263 QQQQQQQQQQQQQQQQQQQQQQQL 286
Score = 33.1 bits (74), Expect = 0.43
Identities = 18/38 (47%), Positives = 23/38 (60%)
Query: 72 QQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
QQQQQQQQQQQQQ Q+ Q L R ++ + +Q
Sbjct: 261 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQ 298
Score = 32.3 bits (72), Expect = 0.73
Identities = 28/105 (26%), Positives = 40/105 (38%), Gaps = 19/105 (18%)
Query: 9 PGAHSGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYK 68
PG S P+ P + + P +++H P P +Q + Q+
Sbjct: 971 PGYPSQPVEQRPLQQMPPQ-----------LMQHVAPPPQPPQQQPQPQLPQQQQPPPPS 1019
Query: 69 NWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHP 113
Q QQQQQQQQQ + L+ Q K R Q+ HP
Sbjct: 1020 QPQSQQQQQQQQQMMMM-LMMQQ-------DPKSVRLPVSQNVHP 1056
Score = 31.2 bits (69), Expect = 1.6
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 16/82 (19%)
Query: 13 SGPMRPLPKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQ 72
SG + P P ++P++V R P + P +Q ++ Q+ + QQ
Sbjct: 233 SGSLAP-PHHPMQPVSVN----------RQMNPANFPQLQQQQQQQQQQQQQQ-----QQ 276
Query: 73 QQQQQQQQQQQQLDLLFHQRIQ 94
QQQQQQQQQ Q HQ+ Q
Sbjct: 277 QQQQQQQQQLQARPPQQHQQQQ 298
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 38.1 bits (87), Expect = 0.013
Identities = 21/45 (46%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 49 PLSRQVKEVAAQKPSEDIYKN-WQQQQQQQQQQQQQQLDLLFHQR 92
P Q V+ + + +N +QQQQQQQQQQQQQQL HQ+
Sbjct: 510 PAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQ 554
>gi|56118214 zinc finger protein 161 [Homo sapiens]
Length = 521
Score = 38.1 bits (87), Expect = 0.013
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 42 HTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRK 101
+TC + + +E + QK + + QQQQQQQQQQQQ Q + LW
Sbjct: 317 NTCKQGISKTCMSEETSNQKQQQ---QQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEA 373
Query: 102 QKRRKTE 108
K RK E
Sbjct: 374 VKARKKE 380
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 37.7 bits (86), Expect = 0.017
Identities = 22/72 (30%), Positives = 37/72 (51%)
Query: 36 NSTMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQI 95
NS P +P + + + + + QQQQQQQQQQQQQQ Q+ Q
Sbjct: 563 NSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQS 622
Query: 96 SLWPRKQKRRKT 107
S+ ++Q+++++
Sbjct: 623 SISAQQQQQQQS 634
Score = 37.7 bits (86), Expect = 0.017
Identities = 19/58 (32%), Positives = 35/58 (60%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
+Q ++ Q+ + + QQQQQQQQQQQQ + Q+ Q S+ ++Q++++ +Q
Sbjct: 591 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQ 648
Score = 37.4 bits (85), Expect = 0.023
Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 4/62 (6%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQ----ISLWPRKQKRRKT 107
+Q ++ Q+ + + QQQQQQQQQQQQQQ + Q+ Q IS ++Q++++
Sbjct: 589 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQ 648
Query: 108 EQ 109
+Q
Sbjct: 649 QQ 650
Score = 37.0 bits (84), Expect = 0.030
Identities = 17/33 (51%), Positives = 23/33 (69%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
+Q ++AQ+ + + QQQQQQQQQQQQQQ
Sbjct: 631 QQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663
Score = 35.8 bits (81), Expect = 0.066
Identities = 22/49 (44%), Positives = 26/49 (53%)
Query: 61 KPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
KPS Y QQQQQQQQQQQQQQ Q+ Q ++Q +Q
Sbjct: 580 KPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
Score = 33.5 bits (75), Expect = 0.33
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 5/77 (6%)
Query: 38 TMIRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQ-----QQQQQQQLDLLFHQR 92
+++ +T +Q ++ Q+ + + QQQQQQQ QQQQQQQ + Q+
Sbjct: 582 SLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQ 641
Query: 93 IQISLWPRKQKRRKTEQ 109
Q ++Q++++ +Q
Sbjct: 642 QQQQQQQQQQQQQQQQQ 658
Score = 33.5 bits (75), Expect = 0.33
Identities = 20/51 (39%), Positives = 26/51 (50%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQ 102
+Q ++AQ+ + QQQQQQQQQQQQQ Q+ Q P Q
Sbjct: 619 QQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ 669
Score = 33.5 bits (75), Expect = 0.33
Identities = 16/38 (42%), Positives = 24/38 (63%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
S+ +Q ++ ++ + + QQQQQQQQQQQQQQ
Sbjct: 623 SISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQ 660
Score = 33.5 bits (75), Expect = 0.33
Identities = 21/73 (28%), Positives = 33/73 (45%)
Query: 50 LSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQ 109
+S Q ++ Q+ + + QQQQQQQQQ Q L Q + S P +QK +
Sbjct: 636 ISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQM 695
Query: 110 HSHPFVKKAFRFS 122
+ P ++ S
Sbjct: 696 QNQPIAGMGYQVS 708
Score = 33.1 bits (74), Expect = 0.43
Identities = 20/40 (50%), Positives = 23/40 (57%)
Query: 60 QKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWP 99
Q+ S + QQQQQQQQQQQQQQ Q+ Q S P
Sbjct: 631 QQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQP 670
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 37.7 bits (86), Expect = 0.017
Identities = 67/273 (24%), Positives = 99/273 (36%), Gaps = 54/273 (19%)
Query: 40 IRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWP 99
++H P L +Q ++ Q+ + QQQQQQQQQQQQ+Q L +++
Sbjct: 512 LQHPAPDHQSLQQQQQQQQQQQQQQQ----QQQQQQQQQQQQQRQNAALMIKQMASRNQQ 567
Query: 100 RKQKRRKTEQHSHP-FVKKAFRFSAG--SGCGRPSSNKMLRSMGGGQRPTGLGSEFFRLL 156
++ ++ Q HP V + G G +P+ + S G G+ LG+ +
Sbjct: 568 QRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGR----LGTFEQQAP 623
Query: 157 HDLHLLAFAMKRIWI------------HRRG----EATARPRAPEHPAPPATAVRG--RD 198
H A + W R G A P P PP G
Sbjct: 624 H------LAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFR 677
Query: 199 AASQNLKRRPGSG------TDGLRLQGAEPS-RLLRTYAGGAVIPTGTPERAQPPP---- 247
Q R PG G + GL+ G+ L++ G +P+ ER PPP
Sbjct: 678 GPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFAT 737
Query: 248 ------PQDPLGRRRWLSRNTWGPWPGTTQPPS 274
P P G ++T PG PPS
Sbjct: 738 SALGGQPGFPFGAAG--RQSTPHSGPGVNSPPS 768
Score = 29.3 bits (64), Expect = 6.2
Identities = 14/22 (63%), Positives = 16/22 (72%)
Query: 71 QQQQQQQQQQQQQQLDLLFHQR 92
QQ QQQQQ QQQQQ +F +R
Sbjct: 295 QQPQQQQQPQQQQQQHGVFFER 316
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 37.7 bits (86), Expect = 0.017
Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 12/99 (12%)
Query: 178 TARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEPSRLLRTYAGGAV-IP 236
T RP AP P P V G ++ PGSG+ G P L R G ++ P
Sbjct: 565 TKRP-APARPTMPPPQVSGSRSSPPAPPLPPGSGSPGT------PQALPRRLVGSSLRAP 617
Query: 237 TGTPERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSP 275
T P P PP P RR R+ P P + P SP
Sbjct: 618 TVPP----PLPPTPPQPARRQSRRSPASPSPASPGPASP 652
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 37.4 bits (85), Expect = 0.023
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 2 GPLFTTIPGAHSGPMR-PLPKKHVEPMAVRQLLLGNSTMIR-----HTCPMSVPLSRQVK 55
G L P A S P R P P V+ +R +L + R T ++V R +
Sbjct: 154 GALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLP 213
Query: 56 EVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
+ Q+ + + QQQQQQQQQQ QQQ
Sbjct: 214 GLQQQQQQQQQQQQQQQQQQQQQQQPQQQ 242
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 37.4 bits (85), Expect = 0.023
Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 2 GPLFTTIPGAHSGPMR-PLPKKHVEPMAVRQLLLGNSTMIR-----HTCPMSVPLSRQVK 55
G L P A S P R P P V+ +R +L + R T ++V R +
Sbjct: 154 GALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLP 213
Query: 56 EVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
+ Q+ + + QQQQQQQQQQ QQQ
Sbjct: 214 GLQQQQQQQQQQQQQQQQQQQQQQQPQQQ 242
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 37.4 bits (85), Expect = 0.023
Identities = 22/46 (47%), Positives = 26/46 (56%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQ 102
VA Q S + QQQQQQQQQQQQQQ L +Q ++ KQ
Sbjct: 1163 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQ 1208
Score = 36.6 bits (83), Expect = 0.039
Identities = 17/33 (51%), Positives = 22/33 (66%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLF 89
+ A + + + QQQQQQQQQQQQQQ +LF
Sbjct: 1162 IVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILF 1194
Score = 31.6 bits (70), Expect = 1.3
Identities = 20/52 (38%), Positives = 25/52 (48%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQIS 96
P +P S+Q +Q + N Q+QQQQQQQQQQ Q I S
Sbjct: 1144 PNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFS 1195
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 37.4 bits (85), Expect = 0.023
Identities = 22/46 (47%), Positives = 26/46 (56%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQ 102
VA Q S + QQQQQQQQQQQQQQ L +Q ++ KQ
Sbjct: 1239 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQ 1284
Score = 36.6 bits (83), Expect = 0.039
Identities = 17/33 (51%), Positives = 22/33 (66%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLF 89
+ A + + + QQQQQQQQQQQQQQ +LF
Sbjct: 1238 IVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILF 1270
Score = 31.6 bits (70), Expect = 1.3
Identities = 20/52 (38%), Positives = 25/52 (48%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQIS 96
P +P S+Q +Q + N Q+QQQQQQQQQQ Q I S
Sbjct: 1220 PNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFS 1271
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 37.4 bits (85), Expect = 0.023
Identities = 22/46 (47%), Positives = 26/46 (56%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQ 102
VA Q S + QQQQQQQQQQQQQQ L +Q ++ KQ
Sbjct: 1256 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQ 1301
Score = 36.6 bits (83), Expect = 0.039
Identities = 17/33 (51%), Positives = 22/33 (66%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLF 89
+ A + + + QQQQQQQQQQQQQQ +LF
Sbjct: 1255 IVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILF 1287
Score = 31.6 bits (70), Expect = 1.3
Identities = 20/52 (38%), Positives = 25/52 (48%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQIS 96
P +P S+Q +Q + N Q+QQQQQQQQQQ Q I S
Sbjct: 1237 PNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFS 1288
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 37.4 bits (85), Expect = 0.023
Identities = 22/46 (47%), Positives = 26/46 (56%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQ 102
VA Q S + QQQQQQQQQQQQQQ L +Q ++ KQ
Sbjct: 1257 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQ 1302
Score = 36.6 bits (83), Expect = 0.039
Identities = 17/33 (51%), Positives = 22/33 (66%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLF 89
+ A + + + QQQQQQQQQQQQQQ +LF
Sbjct: 1256 IVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILF 1288
Score = 31.6 bits (70), Expect = 1.3
Identities = 20/52 (38%), Positives = 25/52 (48%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQIS 96
P +P S+Q +Q + N Q+QQQQQQQQQQ Q I S
Sbjct: 1238 PNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFS 1289
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 37.4 bits (85), Expect = 0.023
Identities = 22/46 (47%), Positives = 26/46 (56%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQ 102
VA Q S + QQQQQQQQQQQQQQ L +Q ++ KQ
Sbjct: 1163 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQ 1208
Score = 36.6 bits (83), Expect = 0.039
Identities = 17/33 (51%), Positives = 22/33 (66%)
Query: 57 VAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLF 89
+ A + + + QQQQQQQQQQQQQQ +LF
Sbjct: 1162 IVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILF 1194
Score = 31.6 bits (70), Expect = 1.3
Identities = 20/52 (38%), Positives = 25/52 (48%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQIS 96
P +P S+Q +Q + N Q+QQQQQQQQQQ Q I S
Sbjct: 1144 PNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFS 1195
>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
Length = 796
Score = 37.4 bits (85), Expect = 0.023
Identities = 18/29 (62%), Positives = 22/29 (75%)
Query: 58 AAQKPSEDIYKNWQQQQQQQQQQQQQQLD 86
AAQ+ + + QQQQQQQQQQQQQQL+
Sbjct: 101 AAQQQQQQQQQQQQQQQQQQQQQQQQQLN 129
Score = 34.3 bits (77), Expect = 0.19
Identities = 18/33 (54%), Positives = 20/33 (60%)
Query: 58 AAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFH 90
AA + + QQQQQQQQQQQQQQ L H
Sbjct: 98 AAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNH 130
Score = 33.5 bits (75), Expect = 0.33
Identities = 21/50 (42%), Positives = 27/50 (54%)
Query: 47 SVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQIS 96
+V LS + AA + QQQQQQQQQQQQQQ Q+ Q++
Sbjct: 80 TVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLN 129
Score = 31.6 bits (70), Expect = 1.3
Identities = 36/113 (31%), Positives = 39/113 (34%), Gaps = 24/113 (21%)
Query: 182 RAPEHP----APPATAVRGRDAASQNLKRR----PGSGTDGLRLQGAEPSRL-------- 225
RAP P A P A GR AA+ KR+ P +G G E R
Sbjct: 516 RAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSE 575
Query: 226 ---LRTYAGGAVIPTGTPERAQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSP 275
L AGG P PPPP PLG S T P PSP
Sbjct: 576 ALKLTMSAGGFAAPGHAA--GGPPPPPPPLGPH---SNRTTPPESAPQNGPSP 623
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 37.0 bits (84), Expect = 0.030
Identities = 19/45 (42%), Positives = 29/45 (64%)
Query: 40 IRHTCPMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
I++T +S+ +Q ++ Q+ + + QQQQQQQQQQQQQQ
Sbjct: 43 IQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 87
Score = 35.0 bits (79), Expect = 0.11
Identities = 17/33 (51%), Positives = 22/33 (66%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
RQ ++ Q+ + + QQQQQQQQQQQQQQ
Sbjct: 57 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 89
Score = 34.7 bits (78), Expect = 0.15
Identities = 19/49 (38%), Positives = 30/49 (61%)
Query: 63 SEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHS 111
S I + Q+QQQQQQQQQQQQ Q+ Q ++Q++++ +Q +
Sbjct: 48 SLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQA 96
Score = 33.9 bits (76), Expect = 0.25
Identities = 18/45 (40%), Positives = 26/45 (57%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQLDLLFHQRIQIS 96
+Q ++ Q+ + + QQQQQQQQQQQQQQ + +Q S
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQS 105
Score = 33.5 bits (75), Expect = 0.33
Identities = 16/33 (48%), Positives = 22/33 (66%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
+Q ++ Q+ + + QQQQQQQQQQQQQQ
Sbjct: 58 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 90
Score = 33.5 bits (75), Expect = 0.33
Identities = 16/33 (48%), Positives = 22/33 (66%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
+Q ++ Q+ + + QQQQQQQQQQQQQQ
Sbjct: 59 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 91
Score = 33.5 bits (75), Expect = 0.33
Identities = 16/33 (48%), Positives = 22/33 (66%)
Query: 52 RQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
+Q ++ Q+ + + QQQQQQQQQQQQQQ
Sbjct: 60 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 92
Score = 33.1 bits (74), Expect = 0.43
Identities = 16/40 (40%), Positives = 23/40 (57%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
P + + + + Q+ + + QQQQQQQQQQQQQQ
Sbjct: 40 PQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQ 79
Score = 33.1 bits (74), Expect = 0.43
Identities = 20/48 (41%), Positives = 28/48 (58%), Gaps = 5/48 (10%)
Query: 71 QQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKA 118
QQQQQQQQQQQQQQ Q+ Q ++Q++++ +Q V A
Sbjct: 58 QQQQQQQQQQQQQQ-----QQQQQQQQQQQQQQQQQQQQQQQQAVAAA 100
Score = 32.7 bits (73), Expect = 0.56
Identities = 17/40 (42%), Positives = 23/40 (57%)
Query: 45 PMSVPLSRQVKEVAAQKPSEDIYKNWQQQQQQQQQQQQQQ 84
P+ S + E ++ + + QQQQQQQQQQQQQQ
Sbjct: 42 PIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQ 81
Score = 32.7 bits (73), Expect = 0.56
Identities = 19/64 (29%), Positives = 33/64 (51%)
Query: 71 QQQQQQQQQQQQQQLDLLFHQRIQISLWPRKQKRRKTEQHSHPFVKKAFRFSAGSGCGRP 130
+QQ+QQQQQQQQQQ Q+ Q ++Q++++ +Q A + S +
Sbjct: 54 EQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQG 113
Query: 131 SSNK 134
+S +
Sbjct: 114 TSGQ 117
>gi|120952764 mastermind-like domain containing 1 [Homo sapiens]
Length = 774
Score = 37.0 bits (84), Expect = 0.030
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 23/89 (25%)
Query: 2 GPLFTTIPGAHSGPMRPL-PKKHVEPMAVRQLLLGNSTMIRHTCPMSVPLSRQVKEVAAQ 60
G L + +P ++ GP P P+K P +Q ++IR P S LS
Sbjct: 441 GHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLIRSLTPTSNLLS--------- 491
Query: 61 KPSEDIYKNWQQQQQQQQQQQQQQLDLLF 89
QQQQQQQQQQQ +++F
Sbjct: 492 -------------QQQQQQQQQQQANVIF 507
>gi|90403598 mesoderm posterior 2 homolog [Homo sapiens]
Length = 397
Score = 37.0 bits (84), Expect = 0.030
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 1/43 (2%)
Query: 243 AQPPPPQDPLGRRRWLSRNTWGPWPGTTQPPSPQLLRNDWGSC 285
AQ PPPQ LG W+ WG W G SP + GSC
Sbjct: 2 AQSPPPQSLLGHDHWIFAQGWG-WAGHWDSTSPASSSDSSGSC 43
>gi|239746282 PREDICTED: hypothetical protein XP_002343723 [Homo
sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.039
Identities = 18/51 (35%), Positives = 22/51 (43%)
Query: 172 HRRGEATARPRAPEHPAPPATAVRGRDAASQNLKRRPGSGTDGLRLQGAEP 222
H +G RP P APP G + + NL+R PG G L G P
Sbjct: 523 HGQGVDLTRPSRPRLSAPPDITAFGEEGETDNLRRHPGVGPRSAHLGGLVP 573
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,543,703
Number of Sequences: 37866
Number of extensions: 1060319
Number of successful extensions: 10484
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 6866
Number of HSP's gapped (non-prelim): 1892
length of query: 383
length of database: 18,247,518
effective HSP length: 104
effective length of query: 279
effective length of database: 14,309,454
effective search space: 3992337666
effective search space used: 3992337666
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.