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Search of human proteins with 223633986
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223633986 trace amine associated receptor 5 [Homo sapiens]
(337 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223633986 trace amine associated receptor 5 [Homo sapiens] 691 0.0
gi|110618256 trace amine associated receptor 9 [Homo sapiens] 316 2e-86
gi|16751917 trace amine associated receptor 8 [Homo sapiens] 306 2e-83
gi|28173558 trace amine associated receptor 6 [Homo sapiens] 304 6e-83
gi|74275344 trace amine associated receptor 2 isoform 1 [Homo sa... 285 3e-77
gi|74275342 trace amine associated receptor 2 isoform 2 [Homo sa... 271 8e-73
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 260 1e-69
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 165 5e-41
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 165 5e-41
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 165 5e-41
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 165 5e-41
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 165 5e-41
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 165 5e-41
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 161 9e-40
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 155 4e-38
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 155 4e-38
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 150 1e-36
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 149 5e-36
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 149 5e-36
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 149 5e-36
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 149 5e-36
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 139 3e-33
gi|4503383 dopamine receptor D1 [Homo sapiens] 139 5e-33
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 137 1e-32
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 137 2e-32
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 136 2e-32
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 132 3e-31
gi|4503391 dopamine receptor D5 [Homo sapiens] 132 4e-31
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 129 5e-30
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 129 5e-30
>gi|223633986 trace amine associated receptor 5 [Homo sapiens]
Length = 337
Score = 691 bits (1784), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MRAVFIQGAEEHPAAFCYQVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVS 60
MRAVFIQGAEEHPAAFCYQVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVS
Sbjct: 1 MRAVFIQGAEEHPAAFCYQVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVS 60
Query: 61 YFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLT 120
YFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLT
Sbjct: 61 YFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLT 120
Query: 121 SIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLS 180
SIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLS
Sbjct: 121 SIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLS 180
Query: 181 QWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSL 240
QWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSL
Sbjct: 181 QWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSL 240
Query: 241 AGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSAC 300
AGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSAC
Sbjct: 241 AGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSAC 300
Query: 301 NPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337
NPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
Sbjct: 301 NPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337
>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
Length = 348
Score = 316 bits (809), Expect = 2e-86
Identities = 153/330 (46%), Positives = 217/330 (65%), Gaps = 9/330 (2%)
Query: 17 CYQ-VNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLS 75
CY+ VN SC +T ++ G + ++Y G ++ GN+ V A+ +FK LHTPTNFL+ S
Sbjct: 14 CYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIAS 73
Query: 76 LALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCA 135
LA AD +G+ V+P ST+RSVESCW+FGD C+ HT DT FC S+FHLC IS+DR+ A
Sbjct: 74 LACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIA 133
Query: 136 ICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLL 195
+ DPL YP+KFTV V+ I+ W Y+ YT E + + + + CVG CQ
Sbjct: 134 VTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAP 193
Query: 196 LNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQI-TTLSKSLAGA-------AKHE 247
LN+ W L F LFF+P + M+ +Y KIF+VA QA++I +T S++ + + AK E
Sbjct: 194 LNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRE 253
Query: 248 RKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVF 307
RKAAKTLGIA+ +L+ WLP+ +D ++D+ ++FITPP V++I +W Y+NSA NP+IY F
Sbjct: 254 RKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAF 313
Query: 308 SYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337
YQWF KA+KL +S KV + T +L+ E
Sbjct: 314 FYQWFGKAIKLIVSGKVLRTDSSTTNLFSE 343
>gi|16751917 trace amine associated receptor 8 [Homo sapiens]
Length = 342
Score = 306 bits (783), Expect = 2e-83
Identities = 146/330 (44%), Positives = 215/330 (65%), Gaps = 9/330 (2%)
Query: 17 CYQ-VNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLS 75
CY+ VNGSC T ++ G ++++Y A + G L+ V GN+ V +V +FK LH+PTNFL+ S
Sbjct: 13 CYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIAS 72
Query: 76 LALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCA 135
LA AD +G+ V+ S +R+VESCW+FG C LH+ D FC +S+ HLCFI IDR+
Sbjct: 73 LACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIV 132
Query: 136 ICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLL 195
+ DPL+Y +KFTV V+ I W +P Y+ YT V + L + + + CVG CQ++
Sbjct: 133 VTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQII 192
Query: 196 LNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA--------AKHE 247
+++ W ++F LFF+P L+MI LY KIF++A +QA +I T S + + AK E
Sbjct: 193 VSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRE 252
Query: 248 RKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVF 307
RKAAKTLG+ V +++ WLP+T+D ++D+ + F+TP +++I W AY+NSA NP+IY
Sbjct: 253 RKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYAL 312
Query: 308 SYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337
Y WFRKA+KL LS V + T+ L+ E
Sbjct: 313 FYPWFRKAIKLILSGDVLKASSSTISLFLE 342
>gi|28173558 trace amine associated receptor 6 [Homo sapiens]
Length = 345
Score = 304 bits (779), Expect = 6e-83
Identities = 146/330 (44%), Positives = 216/330 (65%), Gaps = 9/330 (2%)
Query: 17 CY-QVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLS 75
CY VNGSC + + G ++++Y+ G ++ V GN+ V ++ +FK LH+PTNFL+ S
Sbjct: 14 CYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVAS 73
Query: 76 LALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCA 135
LA AD +G+ V+P S +R+VESCW+FG C HT D FC +S+FHLCFISIDR+ A
Sbjct: 74 LACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIA 133
Query: 136 ICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLL 195
+ DPL+YP+KFTV V+ I W +P Y+ YT V + L + + + C+G CQ +
Sbjct: 134 VTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTV 193
Query: 196 LNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQI-TTLSKS-------LAGAAKHE 247
+N+ W +F FF+P IMI LY IF+VA RQA++I T SK+ A A+ E
Sbjct: 194 VNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRE 253
Query: 248 RKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVF 307
RKAAKTLG+ V +++ WLP++ID+++D+ + FITP +++I W AY+NSA NP+IY
Sbjct: 254 RKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYAL 313
Query: 308 SYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337
Y WFRKA+K+ ++ +V + T++L+ E
Sbjct: 314 FYPWFRKAIKVIVTGQVLKNSSATMNLFSE 343
>gi|74275344 trace amine associated receptor 2 isoform 1 [Homo
sapiens]
Length = 351
Score = 285 bits (730), Expect = 3e-77
Identities = 133/307 (43%), Positives = 191/307 (62%), Gaps = 1/307 (0%)
Query: 21 NGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALAD 80
N SCP +LG+++ +Y A + I + GN+ + ++SYFK LHTPTNFL+LS+A+ D
Sbjct: 30 NRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITD 89
Query: 81 MFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPL 140
LG ++P S IRSVE+CW+FG C+++ D + +TSIFHLC ++IDR AIC PL
Sbjct: 90 FLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPL 149
Query: 141 LYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFW 200
LY +K T+ V R +L W VP A+ ++++ + + + C SC ++ NK W
Sbjct: 150 LYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLW 209
Query: 201 GWLNFPL-FFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVG 259
G F FF P +M+ +Y KIF V+ + A I L ++ K ++KAAKTLGI +G
Sbjct: 210 GTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIG 269
Query: 260 IYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLT 319
++LLCW P ++D L+F TP ++FD WF YFNS CNP+IY F Y WFR+ALK
Sbjct: 270 VFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYI 329
Query: 320 LSQKVFS 326
L K+FS
Sbjct: 330 LLGKIFS 336
>gi|74275342 trace amine associated receptor 2 isoform 2 [Homo
sapiens]
Length = 306
Score = 271 bits (692), Expect = 8e-73
Identities = 127/291 (43%), Positives = 181/291 (62%), Gaps = 1/291 (0%)
Query: 37 IYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSV 96
+Y A + I + GN+ + ++SYFK LHTPTNFL+LS+A+ D LG ++P S IRSV
Sbjct: 1 MYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSV 60
Query: 97 ESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYIL 156
E+CW+FG C+++ D + +TSIFHLC ++IDR AIC PLLY +K T+ V R +L
Sbjct: 61 ENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLL 120
Query: 157 AGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFPL-FFVPCLIM 215
W VP A+ ++++ + + + C SC ++ NK WG F FF P +M
Sbjct: 121 LCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMM 180
Query: 216 ISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVD 275
+ +Y KIF V+ + A I L ++ K ++KAAKTLGI +G++LLCW P ++D
Sbjct: 181 VGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLD 240
Query: 276 SLLHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFS 326
L+F TP ++FD WF YFNS CNP+IY F Y WFR+ALK L K+FS
Sbjct: 241 PFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFS 291
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 260 bits (664), Expect = 1e-69
Identities = 129/333 (38%), Positives = 196/333 (58%), Gaps = 11/333 (3%)
Query: 16 FCYQV-NGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLL 74
FC+ + N SC + + ++ +Y +L ++GN+ V ++S+FK LHTPTN+L+
Sbjct: 4 FCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIH 63
Query: 75 SLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHC 134
S+A D LG LV+P S +RS E CW+FG+ C++HT D + SIFHL FISIDR+
Sbjct: 64 SMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYY 123
Query: 135 AICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQ-WLEEMPCVGSCQ 193
A+CDPL Y +K + V I W VPA + ++ ++ + + + + C G C
Sbjct: 124 AVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCS 183
Query: 194 LLLNKFWGWLNF-PLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSL--------AGAA 244
+ +K G L F F++P IM+ +Y +I+++A QA+ I+ ++ L +
Sbjct: 184 VFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQ 243
Query: 245 KHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPII 304
ERKA KTLGI +G++L+CW PF I T++D LH+I PP + D+ IWF Y NS NP++
Sbjct: 244 SKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMV 303
Query: 305 YVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE 337
Y F Y WFRKALK+ L K+F + L+ E
Sbjct: 304 YAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLE 336
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 165 bits (418), Expect = 5e-41
Identities = 106/315 (33%), Positives = 166/315 (52%), Gaps = 34/315 (10%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHT-PTNFLLLSLALADMFLGLLVLPLST 92
++V+ + +L+ +LGN+ V AV + + L TN+ ++SLA AD+ + +LV+P
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 93 IRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAI-CDPLLYPSKFT-VRV 150
I V+ W +G+ C + T LD L SIFHLC IS+DR+ AI C PL+Y +K T +R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 151 ALRYILAG-WGVPAAYTSLFL--------YTDVVETR-LSQWLEEMPCVGSCQLLLNKFW 200
AL +L G W +P + L + D++E R +Q CV ++NK +
Sbjct: 139 AL--MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCV----FMVNKPY 192
Query: 201 G-WLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA--------------AK 245
+ F++P L+M+ Y +I+V A A QI L ++ A + +
Sbjct: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252
Query: 246 HERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIY 305
E KAAKTL I +G + LCW PF + +VD + + P V+ F+W Y NS NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312
Query: 306 VFSYQWFRKALKLTL 320
F + FR+A + L
Sbjct: 313 AFLNKSFRRAFLIIL 327
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 165 bits (418), Expect = 5e-41
Identities = 106/315 (33%), Positives = 166/315 (52%), Gaps = 34/315 (10%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHT-PTNFLLLSLALADMFLGLLVLPLST 92
++V+ + +L+ +LGN+ V AV + + L TN+ ++SLA AD+ + +LV+P
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 93 IRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAI-CDPLLYPSKFT-VRV 150
I V+ W +G+ C + T LD L SIFHLC IS+DR+ AI C PL+Y +K T +R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 151 ALRYILAG-WGVPAAYTSLFL--------YTDVVETR-LSQWLEEMPCVGSCQLLLNKFW 200
AL +L G W +P + L + D++E R +Q CV ++NK +
Sbjct: 139 AL--MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCV----FMVNKPY 192
Query: 201 G-WLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA--------------AK 245
+ F++P L+M+ Y +I+V A A QI L ++ A + +
Sbjct: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252
Query: 246 HERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIY 305
E KAAKTL I +G + LCW PF + +VD + + P V+ F+W Y NS NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312
Query: 306 VFSYQWFRKALKLTL 320
F + FR+A + L
Sbjct: 313 AFLNKSFRRAFLIIL 327
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 165 bits (418), Expect = 5e-41
Identities = 106/315 (33%), Positives = 166/315 (52%), Gaps = 34/315 (10%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHT-PTNFLLLSLALADMFLGLLVLPLST 92
++V+ + +L+ +LGN+ V AV + + L TN+ ++SLA AD+ + +LV+P
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 93 IRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAI-CDPLLYPSKFT-VRV 150
I V+ W +G+ C + T LD L SIFHLC IS+DR+ AI C PL+Y +K T +R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 151 ALRYILAG-WGVPAAYTSLFL--------YTDVVETR-LSQWLEEMPCVGSCQLLLNKFW 200
AL +L G W +P + L + D++E R +Q CV ++NK +
Sbjct: 139 AL--MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCV----FMVNKPY 192
Query: 201 G-WLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA--------------AK 245
+ F++P L+M+ Y +I+V A A QI L ++ A + +
Sbjct: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252
Query: 246 HERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIY 305
E KAAKTL I +G + LCW PF + +VD + + P V+ F+W Y NS NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312
Query: 306 VFSYQWFRKALKLTL 320
F + FR+A + L
Sbjct: 313 AFLNKSFRRAFLIIL 327
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 165 bits (418), Expect = 5e-41
Identities = 106/315 (33%), Positives = 166/315 (52%), Gaps = 34/315 (10%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHT-PTNFLLLSLALADMFLGLLVLPLST 92
++V+ + +L+ +LGN+ V AV + + L TN+ ++SLA AD+ + +LV+P
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 93 IRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAI-CDPLLYPSKFT-VRV 150
I V+ W +G+ C + T LD L SIFHLC IS+DR+ AI C PL+Y +K T +R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 151 ALRYILAG-WGVPAAYTSLFL--------YTDVVETR-LSQWLEEMPCVGSCQLLLNKFW 200
AL +L G W +P + L + D++E R +Q CV ++NK +
Sbjct: 139 AL--MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCV----FMVNKPY 192
Query: 201 G-WLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA--------------AK 245
+ F++P L+M+ Y +I+V A A QI L ++ A + +
Sbjct: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252
Query: 246 HERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIY 305
E KAAKTL I +G + LCW PF + +VD + + P V+ F+W Y NS NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312
Query: 306 VFSYQWFRKALKLTL 320
F + FR+A + L
Sbjct: 313 AFLNKSFRRAFLIIL 327
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 165 bits (418), Expect = 5e-41
Identities = 106/315 (33%), Positives = 166/315 (52%), Gaps = 34/315 (10%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHT-PTNFLLLSLALADMFLGLLVLPLST 92
++V+ + +L+ +LGN+ V AV + + L TN+ ++SLA AD+ + +LV+P
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 93 IRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAI-CDPLLYPSKFT-VRV 150
I V+ W +G+ C + T LD L SIFHLC IS+DR+ AI C PL+Y +K T +R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 151 ALRYILAG-WGVPAAYTSLFL--------YTDVVETR-LSQWLEEMPCVGSCQLLLNKFW 200
AL +L G W +P + L + D++E R +Q CV ++NK +
Sbjct: 139 AL--MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCV----FMVNKPY 192
Query: 201 G-WLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA--------------AK 245
+ F++P L+M+ Y +I+V A A QI L ++ A + +
Sbjct: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252
Query: 246 HERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIY 305
E KAAKTL I +G + LCW PF + +VD + + P V+ F+W Y NS NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312
Query: 306 VFSYQWFRKALKLTL 320
F + FR+A + L
Sbjct: 313 AFLNKSFRRAFLIIL 327
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 165 bits (418), Expect = 5e-41
Identities = 106/315 (33%), Positives = 166/315 (52%), Gaps = 34/315 (10%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHT-PTNFLLLSLALADMFLGLLVLPLST 92
++V+ + +L+ +LGN+ V AV + + L TN+ ++SLA AD+ + +LV+P
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 93 IRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAI-CDPLLYPSKFT-VRV 150
I V+ W +G+ C + T LD L SIFHLC IS+DR+ AI C PL+Y +K T +R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 151 ALRYILAG-WGVPAAYTSLFL--------YTDVVETR-LSQWLEEMPCVGSCQLLLNKFW 200
AL +L G W +P + L + D++E R +Q CV ++NK +
Sbjct: 139 AL--MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCV----FMVNKPY 192
Query: 201 G-WLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA--------------AK 245
+ F++P L+M+ Y +I+V A A QI L ++ A + +
Sbjct: 193 AITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR 252
Query: 246 HERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIY 305
E KAAKTL I +G + LCW PF + +VD + + P V+ F+W Y NS NP +Y
Sbjct: 253 TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLY 312
Query: 306 VFSYQWFRKALKLTL 320
F + FR+A + L
Sbjct: 313 AFLNKSFRRAFLIIL 327
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 161 bits (407), Expect = 9e-40
Identities = 105/325 (32%), Positives = 170/325 (52%), Gaps = 40/325 (12%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHT-PTNFLLLSLALADMFLGLLVLPLST 92
++V+ + +L+ +LGN+ V AV + + L TN+ ++SLA AD+ + +LV+P
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 93 IRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAI-CDPLLYPSKFT-VRV 150
I V+ W +G+ C + T LD L SIFHLC IS+DR+ AI C PL+Y +K T +R+
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 151 ALRYILAG-WGVPAAYTSLFL---YTDV----VETRLSQWL-EEMPCVGS---------- 191
AL +L G W +P + L + + ++ +E L+Q L ++ +
Sbjct: 139 AL--MLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNST 196
Query: 192 -CQLLLNKFWG-WLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGA------ 243
C ++NK + + F++P L+M+ Y +I+V A A QI L ++ A +
Sbjct: 197 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS 256
Query: 244 --------AKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAY 295
+ E KAAKTL I +G + LCW PF + +VD + + P V+ F+W Y
Sbjct: 257 ADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGY 316
Query: 296 FNSACNPIIYVFSYQWFRKALKLTL 320
NS NP +Y F + FR+A + L
Sbjct: 317 INSGLNPFLYAFLNKSFRRAFLIIL 341
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 155 bits (393), Expect = 4e-38
Identities = 101/283 (35%), Positives = 149/283 (52%), Gaps = 7/283 (2%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTI 93
++ I + A +LI V GNV V AV + L TN ++SLA+ D+ LGLLVLP S I
Sbjct: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77
Query: 94 RSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFT-VRVAL 152
+ W FG C ++T LD + C SI +L IS+DR+CA+ DPL YP T VRVA+
Sbjct: 78 YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAI 137
Query: 153 RYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLN-FPLFFVP 211
+L W + + T FL + ++ + C++ +N+ +G ++ F++P
Sbjct: 138 SLVLI-WVI--SITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLP 194
Query: 212 CLIMISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFTID 271
LIM Y +IF VA QA++I +S S A E KA TL +G +++CW P+
Sbjct: 195 LLIMCITYYRIFKVARDQAKRINHIS-SWKAATIREHKATVTLAAVMGAFIICWFPYFTA 253
Query: 272 TMVDSLLHFITPPLVFD-IFIWFAYFNSACNPIIYVFSYQWFR 313
+ L V + I +W Y NSA NPI+Y + FR
Sbjct: 254 FVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFR 296
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 155 bits (393), Expect = 4e-38
Identities = 101/283 (35%), Positives = 149/283 (52%), Gaps = 7/283 (2%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTI 93
++ I + A +LI V GNV V AV + L TN ++SLA+ D+ LGLLVLP S I
Sbjct: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77
Query: 94 RSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFT-VRVAL 152
+ W FG C ++T LD + C SI +L IS+DR+CA+ DPL YP T VRVA+
Sbjct: 78 YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAI 137
Query: 153 RYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLN-FPLFFVP 211
+L W + + T FL + ++ + C++ +N+ +G ++ F++P
Sbjct: 138 SLVLI-WVI--SITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLP 194
Query: 212 CLIMISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFTID 271
LIM Y +IF VA QA++I +S S A E KA TL +G +++CW P+
Sbjct: 195 LLIMCITYYRIFKVARDQAKRINHIS-SWKAATIREHKATVTLAAVMGAFIICWFPYFTA 253
Query: 272 TMVDSLLHFITPPLVFD-IFIWFAYFNSACNPIIYVFSYQWFR 313
+ L V + I +W Y NSA NPI+Y + FR
Sbjct: 254 FVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFR 296
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 150 bits (380), Expect = 1e-36
Identities = 104/336 (30%), Positives = 157/336 (46%), Gaps = 52/336 (15%)
Query: 21 NGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALAD 80
N + P+ T I + + L A +L ++GN+ V +V+ + L TPTN+ +++LA+AD
Sbjct: 34 NSTLPQLDITRAISVGLVLG--AFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMAD 91
Query: 81 MFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPL 140
+ L VLP S V W G C + +D L C SI LC ISIDR+ + L
Sbjct: 92 LLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSL 151
Query: 141 LYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVG-SCQLLLNKF 199
YP+ T R A+ +L+ W L T + L W E P C + F
Sbjct: 152 QYPTLVTRRKAILALLSVW---------VLSTVISIGPLLGWKEPAPNDDKECGVTEEPF 202
Query: 200 WG-WLNFPLFFVPCLIMISLYVKIFVVATRQAQQI------------------------- 233
+ + + F++P +++ +Y ++++VA R + +
Sbjct: 203 YALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHE 262
Query: 234 TTLSKSLAGA-------------AKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHF 280
TLS + A E+KAAKTLGI VG+++LCWLPF I + SL
Sbjct: 263 DTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFST 322
Query: 281 ITPP-LVFDIFIWFAYFNSACNPIIYVFSYQWFRKA 315
+ PP VF + W YFNS NPIIY S + F++A
Sbjct: 323 LKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRA 358
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 149 bits (375), Expect = 5e-36
Identities = 109/342 (31%), Positives = 162/342 (47%), Gaps = 53/342 (15%)
Query: 21 NGSCPRTVHTLGIQLVIYLACAAGMLII--VLGNVFVAFAVSYFKALHTPTNFLLLSLAL 78
+ +C + + I I L G LI+ VLGN+ V +V+ + LH+ T++ +++LA+
Sbjct: 11 SSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAV 70
Query: 79 ADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICD 138
AD+ L VLP S I V W FG C + +D L C SI LC ISIDR+ +
Sbjct: 71 ADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSY 130
Query: 139 PLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGS-CQLLLN 197
PL YP+ T R L +L W + + L+ W + P + CQ +N
Sbjct: 131 PLRYPTIVTQRRGLMALLCVWALSLVISIGPLF---------GWRQPAPEDETICQ--IN 179
Query: 198 KFWGWLNFPL---FFVPCLIMISLYVKIFVVATRQ--------------AQQITT---LS 237
+ G++ F F++P I++ +Y +++VVA R+ ++Q+T
Sbjct: 180 EEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRK 239
Query: 238 KSLAGAA------------------KHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLH 279
+ AG + E+KAAKTLGI VG ++LCWLPF + + S
Sbjct: 240 NAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFP 299
Query: 280 FITP-PLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTL 320
P VF I W Y NS NPIIY S Q F+KA + L
Sbjct: 300 DFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 149 bits (375), Expect = 5e-36
Identities = 109/342 (31%), Positives = 162/342 (47%), Gaps = 53/342 (15%)
Query: 21 NGSCPRTVHTLGIQLVIYLACAAGMLII--VLGNVFVAFAVSYFKALHTPTNFLLLSLAL 78
+ +C + + I I L G LI+ VLGN+ V +V+ + LH+ T++ +++LA+
Sbjct: 11 SSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAV 70
Query: 79 ADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICD 138
AD+ L VLP S I V W FG C + +D L C SI LC ISIDR+ +
Sbjct: 71 ADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSY 130
Query: 139 PLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGS-CQLLLN 197
PL YP+ T R L +L W + + L+ W + P + CQ +N
Sbjct: 131 PLRYPTIVTQRRGLMALLCVWALSLVISIGPLF---------GWRQPAPEDETICQ--IN 179
Query: 198 KFWGWLNFPL---FFVPCLIMISLYVKIFVVATRQ--------------AQQITT---LS 237
+ G++ F F++P I++ +Y +++VVA R+ ++Q+T
Sbjct: 180 EEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRK 239
Query: 238 KSLAGAA------------------KHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLH 279
+ AG + E+KAAKTLGI VG ++LCWLPF + + S
Sbjct: 240 NAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFP 299
Query: 280 FITP-PLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTL 320
P VF I W Y NS NPIIY S Q F+KA + L
Sbjct: 300 DFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 149 bits (375), Expect = 5e-36
Identities = 109/342 (31%), Positives = 162/342 (47%), Gaps = 53/342 (15%)
Query: 21 NGSCPRTVHTLGIQLVIYLACAAGMLII--VLGNVFVAFAVSYFKALHTPTNFLLLSLAL 78
+ +C + + I I L G LI+ VLGN+ V +V+ + LH+ T++ +++LA+
Sbjct: 11 SSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAV 70
Query: 79 ADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICD 138
AD+ L VLP S I V W FG C + +D L C SI LC ISIDR+ +
Sbjct: 71 ADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSY 130
Query: 139 PLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGS-CQLLLN 197
PL YP+ T R L +L W + + L+ W + P + CQ +N
Sbjct: 131 PLRYPTIVTQRRGLMALLCVWALSLVISIGPLF---------GWRQPAPEDETICQ--IN 179
Query: 198 KFWGWLNFPL---FFVPCLIMISLYVKIFVVATRQ--------------AQQITT---LS 237
+ G++ F F++P I++ +Y +++VVA R+ ++Q+T
Sbjct: 180 EEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRK 239
Query: 238 KSLAGAA------------------KHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLH 279
+ AG + E+KAAKTLGI VG ++LCWLPF + + S
Sbjct: 240 NAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFP 299
Query: 280 FITP-PLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTL 320
P VF I W Y NS NPIIY S Q F+KA + L
Sbjct: 300 DFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 149 bits (375), Expect = 5e-36
Identities = 109/342 (31%), Positives = 162/342 (47%), Gaps = 53/342 (15%)
Query: 21 NGSCPRTVHTLGIQLVIYLACAAGMLII--VLGNVFVAFAVSYFKALHTPTNFLLLSLAL 78
+ +C + + I I L G LI+ VLGN+ V +V+ + LH+ T++ +++LA+
Sbjct: 11 SSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAV 70
Query: 79 ADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICD 138
AD+ L VLP S I V W FG C + +D L C SI LC ISIDR+ +
Sbjct: 71 ADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSY 130
Query: 139 PLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGS-CQLLLN 197
PL YP+ T R L +L W + + L+ W + P + CQ +N
Sbjct: 131 PLRYPTIVTQRRGLMALLCVWALSLVISIGPLF---------GWRQPAPEDETICQ--IN 179
Query: 198 KFWGWLNFPL---FFVPCLIMISLYVKIFVVATRQ--------------AQQITT---LS 237
+ G++ F F++P I++ +Y +++VVA R+ ++Q+T
Sbjct: 180 EEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRK 239
Query: 238 KSLAGAA------------------KHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLH 279
+ AG + E+KAAKTLGI VG ++LCWLPF + + S
Sbjct: 240 NAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFP 299
Query: 280 FITP-PLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTL 320
P VF I W Y NS NPIIY S Q F+KA + L
Sbjct: 300 DFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVL 341
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 139 bits (351), Expect = 3e-33
Identities = 103/319 (32%), Positives = 149/319 (46%), Gaps = 59/319 (18%)
Query: 35 LVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIR 94
+VI L AA L+I L + AL +NF L+SL +D+ +GL+V+P + +
Sbjct: 35 VVIALTAAANSLLIAL--------ICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLN 86
Query: 95 SVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRY 154
++ W LC L T D + C SI +LC IS+DR+ I PL Y + T AL
Sbjct: 87 ALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALAL 146
Query: 155 ILAGWGVPAAYTSLFLYTDVVETRLSQWLE----EMPCVGSCQLLLNKFWGWLNFPL--- 207
+L W + A + L L L W E P G C+LL + L F L
Sbjct: 147 VLGAWSLAALASFLPL--------LLGWHELGHARPPVPGQCRLLAS-----LPFVLVAS 193
Query: 208 ---FFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAG---------------------- 242
FF+P + Y +I + A +QA Q+ +L+ +A
Sbjct: 194 GLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSR 253
Query: 243 --AAKHERKAAK---TLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFN 297
A KH RKA K TLGI +G++ + WLPF + +V ++ I+P L FD+ W Y N
Sbjct: 254 RLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGL-FDVLTWLGYCN 312
Query: 298 SACNPIIYVFSYQWFRKAL 316
S NPIIY + F++AL
Sbjct: 313 STMNPIIYPLFMRDFKRAL 331
>gi|4503383 dopamine receptor D1 [Homo sapiens]
Length = 446
Score = 139 bits (349), Expect = 5e-33
Identities = 102/344 (29%), Positives = 158/344 (45%), Gaps = 64/344 (18%)
Query: 37 IYLACAAGMLII--VLGNVFVAFAVSYFKALHTP-TNFLLLSLALADMFLGLLVLPLSTI 93
I AC +LI+ +LGN V AV F+ L + TNF ++SLA++D+ + +LV+P +
Sbjct: 24 ILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAV 83
Query: 94 RSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALR 153
+ W FG F C + D + SI +LC IS+DR+ AI P Y K T + A
Sbjct: 84 AEIAGFWPFGSF-CNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFI 142
Query: 154 YILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMP-------------CVGSCQLLLNKFW 200
I W +L + + +LS W + P + +C L++ +
Sbjct: 143 LISVAW-------TLSVLISFIPVQLS-WHKAKPTSPSDGNATSLAETIDNCDSSLSRTY 194
Query: 201 GWLNFPL-FFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGAA--------------- 244
+ + F++P IMI Y +I+ +A +Q ++I L ++ A
Sbjct: 195 AISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECS 254
Query: 245 ----------KHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFI----TPPL----- 285
K E K KTL + +G+++ CWLPF I ++ +L F T P
Sbjct: 255 QPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFI---LNCILPFCGSGETQPFCIDSN 311
Query: 286 VFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQT 329
FD+F+WF + NS+ NPIIY F+ FRKA L P T
Sbjct: 312 TFDVFVWFGWANSSLNPIIYAFNAD-FRKAFSTLLGCYRLCPAT 354
>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
sapiens]
Length = 377
Score = 137 bits (346), Expect = 1e-32
Identities = 105/352 (29%), Positives = 158/352 (44%), Gaps = 73/352 (20%)
Query: 25 PRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLG 84
PRT+ L I L + L+ L VL N FV + + LHTP N+L+ SLA D+ +
Sbjct: 31 PRTLQALKISLAVVLSVIT--LATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVS 88
Query: 85 LLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPS 144
+LV+P+S ++ W FG LC + D C SI HLC I++DR+ AI D L Y
Sbjct: 89 ILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSK 148
Query: 145 KFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMP--CVGSCQLLLNKFWGW 202
+ T A I W + S+ + + R ++ EEM V + Q+ + +
Sbjct: 149 RRTAGHAATMIAIVWAI-----SICISIPPLFWRQAKAQEEMSDCLVNTSQI---SYTIY 200
Query: 203 LNFPLFFVPCLIMISLYVKIFVVATRQ----------------------AQQITTLSKSL 240
F++P +++I LY +I+ A + + +L+ SL
Sbjct: 201 STCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSL 260
Query: 241 -------AG----------------------AAKHERKAAKTLGIAVGIYLLCWLPFTID 271
AG +A ERKA K LGI +G +++CWLPF +
Sbjct: 261 HEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVV 320
Query: 272 TMV-----DSL-LHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALK 317
++V DS +H P +FD F W Y NS NPIIY + FR+A +
Sbjct: 321 SLVLPICRDSCWIH----PALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQ 368
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 137 bits (344), Expect = 2e-32
Identities = 99/329 (30%), Positives = 148/329 (44%), Gaps = 53/329 (16%)
Query: 39 LACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVES 98
L A +L+IV GNV V A++ L T TN ++SLA AD+ +GLLV+P V
Sbjct: 63 LLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWG 122
Query: 99 CWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAG 158
W +G F C L T +D L SI LC I++DR+ AI P Y S T A +
Sbjct: 123 RWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTV 182
Query: 159 WGVPA--AYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFPL-FFVPCLIM 215
W + A ++ + ++ E+ ++ P C + N+ + + + F+VP IM
Sbjct: 183 WAISALVSFLPILMHWWRAESDEARRCYNDP--KCCDFVTNRAYAIASSVVSFYVPLCIM 240
Query: 216 ISLYVKIFVVATRQAQQITTLSKSLAG--------------------------------- 242
+Y+++F A +Q ++I + + G
Sbjct: 241 AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP 300
Query: 243 --------------AAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFD 288
A E+KA KTLGI +G++ LCWLPF + +V + + P +F
Sbjct: 301 LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV 360
Query: 289 IFIWFAYFNSACNPIIYVFSYQWFRKALK 317
F W Y NSA NPIIY S FRKA +
Sbjct: 361 FFNWLGYANSAFNPIIYCRSPD-FRKAFQ 388
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 136 bits (343), Expect = 2e-32
Identities = 102/303 (33%), Positives = 148/303 (48%), Gaps = 32/303 (10%)
Query: 28 VHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLV 87
V +G+ +V+ L +L IV GNV V A++ F+ L T TN+ + SLA AD+ +GL V
Sbjct: 31 VWVVGMGIVMSLI----VLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAV 86
Query: 88 LPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFT 147
+P + W FG+F C T +D L SI LC I++DR+ AI P Y S T
Sbjct: 87 VPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLT 146
Query: 148 VRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGS---CQLLLNKFWGWL- 203
A IL W + + TS FL + R + E + C + C N+ +
Sbjct: 147 KNKARVIILMVW-IVSGLTS-FLPIQMHWYRATH-QEAINCYANETCCDFFTNQAYAIAS 203
Query: 204 NFPLFFVPCLIMISLYVKIFVVATRQAQQI---------TTLSK---------SLAGAAK 245
+ F+VP +IM+ +Y ++F A RQ Q+I LS+ L ++K
Sbjct: 204 SIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSK 263
Query: 246 ---HERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNP 302
E KA KTLGI +G + LCWLPF I +V + + V+ + W Y NS NP
Sbjct: 264 FCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNP 323
Query: 303 IIY 305
+IY
Sbjct: 324 LIY 326
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 132 bits (333), Expect = 3e-31
Identities = 99/342 (28%), Positives = 150/342 (43%), Gaps = 71/342 (20%)
Query: 34 QLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTI 93
++++ + A L L N FV V + LHTP N+L+ SLA+ D+ + +LV+P+ST+
Sbjct: 49 KVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTM 108
Query: 94 RSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALR 153
+V W G +C D C SI HLC I++DR+ AI D + Y +K T + A
Sbjct: 109 YTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAV 168
Query: 154 YILAGW--GVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVP 211
I W + + F E +S+ CV + +L + + F+ P
Sbjct: 169 MIALVWVFSISISLPPFFWRQAKAEEEVSE------CVVNTDHILYTVYSTVG--AFYFP 220
Query: 212 CLIMISLYVKIFVVA---------------TRQAQQITTLSKSLAGA------------- 243
L++I+LY +I+V A +AQ IT S +
Sbjct: 221 TLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSE 280
Query: 244 -------------------------AKHERKAAKTLGIAVGIYLLCWLPFTIDTMV---- 274
A ERKA KTLGI +G +++CWLPF I ++V
Sbjct: 281 SGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPIC 340
Query: 275 -DSLLHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKA 315
D+ + +FD F W Y NS NPIIY S + F++A
Sbjct: 341 KDACWFHLA---IFDFFTWLGYLNSLINPIIYTMSNEDFKQA 379
>gi|4503391 dopamine receptor D5 [Homo sapiens]
Length = 477
Score = 132 bits (332), Expect = 4e-31
Identities = 109/356 (30%), Positives = 168/356 (47%), Gaps = 59/356 (16%)
Query: 37 IYLACAAGMLII--VLGNVFVAFAVSYFKALHTP-TNFLLLSLALADMFLGLLVLPLSTI 93
+ AC +LII +LGNV V A+ + L TN ++SLA++D+F+ LLV+P +
Sbjct: 41 VVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAV 100
Query: 94 RSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALR 153
V W FG F C + D + SI +LC IS+DR+ AI P Y K T R+AL
Sbjct: 101 AEVAGYWPFGAF-CDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALV 159
Query: 154 YILAGWGV-----------------PAAYTSLFLYTDVVETRLSQWLEEM--PCVG--SC 192
+ W + A++ L L ++ + W E+ P V +C
Sbjct: 160 MVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNL--ANWTPWEEDFWEPDVNAENC 217
Query: 193 QLLLNKFWGWLNFPL-FFVPCLIMISLYVKIFVVATRQAQQITTLSK------------- 238
LN+ + + + F++P IMI Y +I+ +A Q ++I++L +
Sbjct: 218 DSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAA 277
Query: 239 -----SLAGAAKHERKAAKTLGIAVGIYLLCWLPFTI-DTMVDSLL-HFITPP------- 284
SL + K E K KTL + +G+++ CWLPF I + MV H PP
Sbjct: 278 CAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVS 337
Query: 285 -LVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQT--RTVDLYQE 337
FD+F+WF + NS+ NP+IY F+ F+K L F +T TV++ E
Sbjct: 338 ETTFDVFVWFGWANSSLNPVIYAFNAD-FQKVFAQLLGCSHFCSRTPVETVNISNE 392
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 129 bits (323), Expect = 5e-30
Identities = 94/317 (29%), Positives = 145/317 (45%), Gaps = 58/317 (18%)
Query: 46 LIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRS-VESCWFFGD 104
L+ + GN V +V + K L P+N+L++SLALAD+ + + V+P ++ + W FG
Sbjct: 93 LLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGH 152
Query: 105 FLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAA 164
F C + +D + C SI LC ISIDR+ I PL YP + + + IL+ W + A+
Sbjct: 153 FFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSAS 212
Query: 165 YTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFP---LFFVPCLIMISLYVK 221
T L+ W + + C L+++ +G+ + F++P +M+ +Y +
Sbjct: 213 ITLPPLF---------GWAQNVNDDKVC--LISQDFGYTIYSTAVAFYIPMSVMLFMYYQ 261
Query: 222 IFVVATRQAQQ-------------------ITTLSK------SLAGAAKHER-------- 248
I+ A + A + I L K +L+ KHER
Sbjct: 262 IYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKR 321
Query: 249 --KAAKTLGIAVGIYLLCWLPF----TIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNP 302
KAA TLGI VG + +CWLPF T + P V F+W Y NS NP
Sbjct: 322 EQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINP 381
Query: 303 IIYVFSYQWFRKALKLT 319
IY F F + L+ T
Sbjct: 382 FIYAF----FNRDLRTT 394
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 129 bits (323), Expect = 5e-30
Identities = 94/317 (29%), Positives = 145/317 (45%), Gaps = 58/317 (18%)
Query: 46 LIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRS-VESCWFFGD 104
L+ + GN V +V + K L P+N+L++SLALAD+ + + V+P ++ + W FG
Sbjct: 93 LLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGH 152
Query: 105 FLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAA 164
F C + +D + C SI LC ISIDR+ I PL YP + + + IL+ W + A+
Sbjct: 153 FFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSAS 212
Query: 165 YTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFP---LFFVPCLIMISLYVK 221
T L+ W + + C L+++ +G+ + F++P +M+ +Y +
Sbjct: 213 ITLPPLF---------GWAQNVNDDKVC--LISQDFGYTIYSTAVAFYIPMSVMLFMYYQ 261
Query: 222 IFVVATRQAQQ-------------------ITTLSK------SLAGAAKHER-------- 248
I+ A + A + I L K +L+ KHER
Sbjct: 262 IYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKR 321
Query: 249 --KAAKTLGIAVGIYLLCWLPF----TIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNP 302
KAA TLGI VG + +CWLPF T + P V F+W Y NS NP
Sbjct: 322 EQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINP 381
Query: 303 IIYVFSYQWFRKALKLT 319
IY F F + L+ T
Sbjct: 382 FIYAF----FNRDLRTT 394
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.333 0.143 0.471
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,449,930
Number of Sequences: 37866
Number of extensions: 442972
Number of successful extensions: 3325
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 613
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 1568
Number of HSP's gapped (non-prelim): 1030
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.