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Search of human proteins with 222537745
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222537745 schlafen family member 12-like [Homo sapiens]
(617 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222537745 schlafen family member 12-like [Homo sapiens] 1257 0.0
gi|157388955 schlafen family member 12 [Homo sapiens] 842 0.0
gi|145580600 schlafen family member 5 [Homo sapiens] 441 e-124
gi|193788705 schlafen family member 14 [Homo sapiens] 423 e-118
gi|56119108 schlafen family member 13 [Homo sapiens] 371 e-103
gi|157388965 schlafen family member 11 [Homo sapiens] 346 3e-95
gi|157388963 schlafen family member 11 [Homo sapiens] 346 3e-95
gi|157388961 schlafen family member 11 [Homo sapiens] 346 3e-95
gi|157388959 schlafen family member 11 [Homo sapiens] 346 3e-95
gi|157388957 schlafen family member 11 [Homo sapiens] 346 3e-95
gi|45267821 schlafen-like 1 [Homo sapiens] 33 0.78
gi|224586875 coiled-coil domain containing 65 [Homo sapiens] 32 1.7
gi|24308516 tubulin tyrosine ligase [Homo sapiens] 32 2.3
gi|7661556 TruB pseudouridine (psi) synthase homolog 2 [Homo sap... 32 2.3
gi|29789401 ubiquitin-conjugating enzyme E2Q 2 isoform 1 [Homo s... 30 5.0
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens] 30 5.0
gi|4507247 SH3 and cysteine rich domain [Homo sapiens] 30 5.0
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens] 30 5.0
gi|70995130 cholinergic receptor, nicotinic, alpha 9 precursor [... 30 6.6
>gi|222537745 schlafen family member 12-like [Homo sapiens]
Length = 617
Score = 1257 bits (3252), Expect = 0.0
Identities = 617/617 (100%), Positives = 617/617 (100%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFIRKEFLRGNGLAAGKMNISIDLDTNYAE 60
MAMKIMEKIRNVFHCEAHRILYICESQFLRNFIRKEFLRGNGLAAGKMNISIDLDTNYAE
Sbjct: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFIRKEFLRGNGLAAGKMNISIDLDTNYAE 60
Query: 61 LVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKD 120
LVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKD
Sbjct: 61 LVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENKGYSYKKD 120
Query: 121 GIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTS 180
GIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTS
Sbjct: 121 GIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIATLSSSLYKRDVTS 180
Query: 181 AKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYK 240
AKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYK
Sbjct: 181 AKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALAADFFNRTELGYK 240
Query: 241 EKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVGLNEDKEVIGFKAE 300
EKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVGLNEDKEVIGFKAE
Sbjct: 241 EKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVGLNEDKEVIGFKAE 300
Query: 301 KSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCA 360
KSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCA
Sbjct: 301 KSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCGYVYALRVERFCCA 360
Query: 361 VFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPSPASTSSPVSQSYPLREYINF 420
VFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPSPASTSSPVSQSYPLREYINF
Sbjct: 361 VFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPSPASTSSPVSQSYPLREYINF 420
Query: 421 KIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDL 480
KIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDL
Sbjct: 421 KIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDL 480
Query: 481 GLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVC 540
GLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVC
Sbjct: 481 GLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVC 540
Query: 541 VMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIFLFVC 600
VMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIFLFVC
Sbjct: 541 VMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIFLFVC 600
Query: 601 LFRFCLFVCWFVCFFLR 617
LFRFCLFVCWFVCFFLR
Sbjct: 601 LFRFCLFVCWFVCFFLR 617
>gi|157388955 schlafen family member 12 [Homo sapiens]
Length = 578
Score = 842 bits (2176), Expect = 0.0
Identities = 430/568 (75%), Positives = 475/568 (83%), Gaps = 10/568 (1%)
Query: 48 MNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIK 107
MNIS+DL+TNYAELVL+VGRVTLGEN+RKKMKDC+LRK+QNE+VSRA+CALLNSGGGVIK
Sbjct: 1 MNISVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIK 60
Query: 108 AEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIA 167
AE+EN+ YSY KDGIGLDLENSFSN+L FVP +LDFMQNGNYF IFVKSWSL TSG +I
Sbjct: 61 AEIENEDYSYTKDGIGLDLENSFSNILLFVPEYLDFMQNGNYFLIFVKSWSLNTSGLRIT 120
Query: 168 TLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEAL 227
TLSS+LYKRD+TSAKVMNA+AALEFLKDM+KT GR YLRPE AKR CVD+QEE+NM+AL
Sbjct: 121 TLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLRPELLAKRPCVDIQEENNMKAL 180
Query: 228 AADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVG 287
A FF+RTEL KEKLTFTESTHVEIKNFSTEKLLQRI EILPQYVSAFANTDGGYLF+G
Sbjct: 181 AGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFANTDGGYLFIG 240
Query: 288 LNEDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLCG 347
LNEDKE+IGFKAE S L LE + SI K+PVHHFC+EK INY CKFLGVYDKG LCG
Sbjct: 241 LNEDKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFLGVYDKGSLCG 300
Query: 348 YVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEP----VCEELPSPAS 403
YV ALRVERFCCAVFAK+PDSWHVKDNRV QLT KEWIQFMV++EP EE+ S +
Sbjct: 301 YVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQIN 360
Query: 404 TSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICEEMG 463
TS P S+PL E+ Q R+H PGLS +IT P+ CR LF QHEGLKQLICEEM
Sbjct: 361 TSLPAPHSWPLLEW-----QRQRHHCPGLSGRITYTPENLCRKLFLQHEGLKQLICEEMD 415
Query: 464 SVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQ 523
SV KGSLIFSRSWS+DLGLQENHKVLCDALLISQD PPVLYTFHMVQDEEFK YSTQTA
Sbjct: 416 SVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQDEEFKGYSTQTAL 475
Query: 524 TLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQ-TMKDLE 582
TLKQKLAKIGGYTKKVCVMTKIFYLSPEG TSCQYDL SQVIYPESYY+T + +K L
Sbjct: 476 TLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESYYFTRRKYLLKALF 535
Query: 583 KALSNILPKENQIFLFVCLFRFCLFVCW 610
KAL + +Q L++ C+
Sbjct: 536 KALKRLKSLRDQFSFAENLYQIIGIDCF 563
>gi|145580600 schlafen family member 5 [Homo sapiens]
Length = 891
Score = 441 bits (1134), Expect = e-124
Identities = 254/549 (46%), Positives = 346/549 (63%), Gaps = 19/549 (3%)
Query: 48 MNISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIK 107
M++ ID+DTN+ E V++ G+VTLG R++M D +LR++QNE + RAVCALLNSGGG+IK
Sbjct: 1 MSLRIDVDTNFPECVVDAGKVTLGTQQRQEM-DPRLREKQNEIILRAVCALLNSGGGIIK 59
Query: 108 AEVENKGYSYKKDGIGLDLENSFSNMLPFVPNFLDFMQNGNYFHIFVKSWSLETSGPQIA 167
AE+ENKGY+Y++ G+GLD+ P + LD MQ N+F IFVKSW+ E P +A
Sbjct: 60 AEIENKGYNYERHGVGLDVP-------PIFRSHLDKMQKENHFLIFVKSWNTEAGVP-LA 111
Query: 168 TLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEAL 227
TL S+LY R+ TS VM++ AL FLK +T + + A VQ E N+
Sbjct: 112 TLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINVS 171
Query: 228 AADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVG 287
AA F+R L Y EKL ESTHVE FST+ + + + LP+ VSAFANT+GGY+F G
Sbjct: 172 AAALFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYVFFG 230
Query: 288 LNEDK-EVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDKGRLC 346
++++ +VIG + EK LT L I KLPVHHFC ++ I Y+ FL V+DKG L
Sbjct: 231 VHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGALR 290
Query: 347 GYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEP---VCEELPSPAS 403
GYV A++VE+FCCAVFAK P SW VKDNRV+QL +EW +M++++P C E+ S
Sbjct: 291 GYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSRCPEMVLQLS 350
Query: 404 TSSPVSQSYPLREYIN---FKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICE 460
SS +S P+ + N K Q RY P S+++ P++ + LFSQH+GL+ LI
Sbjct: 351 LSSATPRSKPVCIHKNSECLKEQQKRY-FPVFSDRVVYTPESLYKELFSQHKGLRDLINT 409
Query: 461 EMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFKDYSTQ 520
EM ++G LIFS+SW++DLGLQE V+CDALLISQ+ P+LYT D K YS
Sbjct: 410 EMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKGYSMI 469
Query: 521 TAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKD 580
A +LKQKL GGYT ++C+ + L+ + K Y Q IYPESY + T Q M+
Sbjct: 470 VAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQ-IYPESYNFMTPQHMEA 528
Query: 581 LEKALSNIL 589
L ++L +L
Sbjct: 529 LLQSLVIVL 537
Score = 50.4 bits (119), Expect = 5e-06
Identities = 25/53 (47%), Positives = 33/53 (62%), Gaps = 12/53 (22%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI------------RKEFLRGN 41
+A++IMEKIRNVFHCE ILYICE+Q L+ + RK F++ N
Sbjct: 587 LALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNN 639
>gi|193788705 schlafen family member 14 [Homo sapiens]
Length = 912
Score = 423 bits (1088), Expect = e-118
Identities = 239/553 (43%), Positives = 349/553 (63%), Gaps = 23/553 (4%)
Query: 49 NISIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKA 108
++ D + Y E++++VGRV GE NRKKM + L++ +N + RA+CALLNSGGGVIKA
Sbjct: 3 SLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKA 62
Query: 109 EVENKGYSYKKDGIGLDLENSFSNMLPF-VPNFLDFMQNGNYFHIFVKSWSLET-SGP-Q 165
E+++K YSY+ G+G DLE SF +LP +LD+MQ G+ IFVKSWS + S P +
Sbjct: 63 EIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLR 122
Query: 166 IATLSSSLYKRDVTSAKVMNASAALEFLKD--MEKTGGRAYLRPEFPAKRACVDVQEESN 223
I +L S+LY+RDVTSA ++AS+ALE L++ GR ++ P + +QEE +
Sbjct: 123 ICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNRCIQEEED 182
Query: 224 MEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGY 283
M LA++FF + +L YKEKL FTESTHVE K F+T+K++ RI E+LP YVSAFANT GGY
Sbjct: 183 MRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGGY 242
Query: 284 LFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYDK 342
+ +G+++ KEV+G K EK L++ +N I KLP HFC EK +N+ K L VY K
Sbjct: 243 VLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQK 302
Query: 343 GRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPS-- 400
L GYV ++VE FCC VFA+ PDSW +KDN V +LT ++W+ M+D++ L +
Sbjct: 303 DVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPSLVTDY 362
Query: 401 -----PASTSSPVSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLK 455
+++S+ S YP++ + FK R+ P E++ P++ C+ LFS H+ L+
Sbjct: 363 NSCLISSASSARKSPGYPIKVH-KFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKELE 421
Query: 456 QLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEFK 515
L+ + ++G +IFSRSW+ D+G ++ VLCDALLI+ + P VLYT ++ D +
Sbjct: 422 GLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYT--ILIDPNWP 479
Query: 516 ---DYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYW 572
+Y+ TA LKQKL +GGYT KVC++ ++ +LS + L YP SY
Sbjct: 480 GGLEYARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQSRPGEIPLR----YPRSYRL 535
Query: 573 TTAQTMKDLEKAL 585
+ M+DL +AL
Sbjct: 536 ADEEEMEDLLQAL 548
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/53 (43%), Positives = 35/53 (66%), Gaps = 10/53 (18%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI----------RKEFLRGNGL 43
+A+KIMEKI+++FHC+ ILY+CES L++F+ RK F++G L
Sbjct: 602 LAIKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQTTCQAVTRKTFMQGEFL 654
>gi|56119108 schlafen family member 13 [Homo sapiens]
Length = 897
Score = 371 bits (953), Expect = e-103
Identities = 216/555 (38%), Positives = 320/555 (57%), Gaps = 19/555 (3%)
Query: 51 SIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEV 110
S+ + +Y +LV++VG VTLGE NRKK++ Q R Q+ V RA CALLNSGGGVI+ E+
Sbjct: 7 SLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQ-RDQERARVIRAACALLNSGGGVIQMEM 65
Query: 111 ENKGYSYKKDGIGLDLENSFSNML--PFVPNFLDFMQNGNYFHIFVKSWSLE------TS 162
N+ + +GLDLE S ++ P++ F + Q+G F+IFVKSWS + +
Sbjct: 66 ANR--DERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKDGSF 123
Query: 163 GPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEES 222
+I +LSSSLY R TS MN+ A +FLK E+ + P + V +
Sbjct: 124 NSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVYQNI 183
Query: 223 NMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGG 282
+ A + F + Y E L+F ES +E K FST+ + Q + I+P+Y+SAFANT+GG
Sbjct: 184 SESNPAYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANTEGG 243
Query: 283 YLFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYD 341
YLF+G+++ ++V+G E+ L+ V +I KLP+ HFC K + Y K + V+
Sbjct: 244 YLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVEVFC 303
Query: 342 KGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEP-----VCE 396
L GY+ ++V+ FCC VF++ P SW V++ ++ LT +EW++ M+D++P E
Sbjct: 304 GKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPDFAE 363
Query: 397 ELPSPASTSSPVSQSYPL--REYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGL 454
S S S S P+ ++ + K ++ P + C P++ + L QHEGL
Sbjct: 364 AFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQHEGL 423
Query: 455 KQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEF 514
K+LI ++M ++G +I SRSW++DL LQE V+CDALLI+Q+ P+LYT QD E
Sbjct: 424 KELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEG 483
Query: 515 KDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTT 574
+DY T+TA TLKQKL +GGYT KVCV K+ LSPE S + YP SY
Sbjct: 484 QDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAG 543
Query: 575 AQTMKDLEKALSNIL 589
Q M+ L ++L +L
Sbjct: 544 TQHMEALLQSLVIVL 558
Score = 66.6 bits (161), Expect = 6e-11
Identities = 30/33 (90%), Positives = 32/33 (96%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI 33
MAMKIMEKIRNVFHCEAHRILY+CE+Q LRNFI
Sbjct: 608 MAMKIMEKIRNVFHCEAHRILYVCENQPLRNFI 640
>gi|157388965 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 346 bits (888), Expect = 3e-95
Identities = 221/560 (39%), Positives = 311/560 (55%), Gaps = 35/560 (6%)
Query: 54 LDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENK 113
++ +Y +LV+NVG VTLGE NRKK++ Q R Q+ E V RA CALLNSGGGVI+ K
Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMA---K 65
Query: 114 GYSYKKDGIGLDLENSFSNMLPF--VPNFLDFMQNGNYFHIFVKSWSL------ETSGPQ 165
+ + +GLDLE S ++ + F + Q G F+IFVKSWS + P+
Sbjct: 66 KVEHPVE-MGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124
Query: 166 IATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEE---- 221
+ +LSSSLY+R TS + M++ A FLK K + E P + V +E
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPK----ILEEGPFHKIHKGVYQELPNS 180
Query: 222 --SNMEALAADF-FNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFAN 278
++ + AD F + L Y E L F ES VE K FST+ + + +P+YV AFAN
Sbjct: 181 DPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFAN 240
Query: 279 TDGGYLFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFL 337
T GGYLF+G+++ +EV+G E L + +I KLP HFC + I + K +
Sbjct: 241 TGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIV 300
Query: 338 GVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEE 397
V +G L GY +RV FCCAVF++ P+SW V+D V LT ++W+ M D++P +
Sbjct: 301 NVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQ 360
Query: 398 LPSPASTSSPVSQSYPLREYINFK--------IQPLRYHLPGLSEKITCAPKTFCRNLFS 449
L +S PL + K +Q L + +P + T P++ R+L S
Sbjct: 361 LSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYT--PESLWRDLIS 418
Query: 450 QHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMV 509
+H GL++LI ++M +G LIFSRSW++DL LQE V+CDALLI+Q+ P+LYT
Sbjct: 419 EHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
Query: 510 QDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPES 569
QD E +DY T+TA TLKQKL +GGYT KVCV K+ LSPE S + YP S
Sbjct: 479 QDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPAS 538
Query: 570 YYWTTAQTMKDLEKALSNIL 589
Y Q M+ L ++L +L
Sbjct: 539 YSLAGTQHMEALLQSLVIVL 558
Score = 69.3 bits (168), Expect = 1e-11
Identities = 36/51 (70%), Positives = 38/51 (74%), Gaps = 10/51 (19%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI----------RKEFLRGN 41
MAMKIMEKIRNVFHCEAHRILY+CE+Q LRNFI RK FLR N
Sbjct: 608 MAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKTFLREN 658
>gi|157388963 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 346 bits (888), Expect = 3e-95
Identities = 221/560 (39%), Positives = 311/560 (55%), Gaps = 35/560 (6%)
Query: 54 LDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENK 113
++ +Y +LV+NVG VTLGE NRKK++ Q R Q+ E V RA CALLNSGGGVI+ K
Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMA---K 65
Query: 114 GYSYKKDGIGLDLENSFSNMLPF--VPNFLDFMQNGNYFHIFVKSWSL------ETSGPQ 165
+ + +GLDLE S ++ + F + Q G F+IFVKSWS + P+
Sbjct: 66 KVEHPVE-MGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124
Query: 166 IATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEE---- 221
+ +LSSSLY+R TS + M++ A FLK K + E P + V +E
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPK----ILEEGPFHKIHKGVYQELPNS 180
Query: 222 --SNMEALAADF-FNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFAN 278
++ + AD F + L Y E L F ES VE K FST+ + + +P+YV AFAN
Sbjct: 181 DPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFAN 240
Query: 279 TDGGYLFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFL 337
T GGYLF+G+++ +EV+G E L + +I KLP HFC + I + K +
Sbjct: 241 TGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIV 300
Query: 338 GVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEE 397
V +G L GY +RV FCCAVF++ P+SW V+D V LT ++W+ M D++P +
Sbjct: 301 NVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQ 360
Query: 398 LPSPASTSSPVSQSYPLREYINFK--------IQPLRYHLPGLSEKITCAPKTFCRNLFS 449
L +S PL + K +Q L + +P + T P++ R+L S
Sbjct: 361 LSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYT--PESLWRDLIS 418
Query: 450 QHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMV 509
+H GL++LI ++M +G LIFSRSW++DL LQE V+CDALLI+Q+ P+LYT
Sbjct: 419 EHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
Query: 510 QDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPES 569
QD E +DY T+TA TLKQKL +GGYT KVCV K+ LSPE S + YP S
Sbjct: 479 QDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPAS 538
Query: 570 YYWTTAQTMKDLEKALSNIL 589
Y Q M+ L ++L +L
Sbjct: 539 YSLAGTQHMEALLQSLVIVL 558
Score = 69.3 bits (168), Expect = 1e-11
Identities = 36/51 (70%), Positives = 38/51 (74%), Gaps = 10/51 (19%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI----------RKEFLRGN 41
MAMKIMEKIRNVFHCEAHRILY+CE+Q LRNFI RK FLR N
Sbjct: 608 MAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKTFLREN 658
>gi|157388961 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 346 bits (888), Expect = 3e-95
Identities = 221/560 (39%), Positives = 311/560 (55%), Gaps = 35/560 (6%)
Query: 54 LDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENK 113
++ +Y +LV+NVG VTLGE NRKK++ Q R Q+ E V RA CALLNSGGGVI+ K
Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMA---K 65
Query: 114 GYSYKKDGIGLDLENSFSNMLPF--VPNFLDFMQNGNYFHIFVKSWSL------ETSGPQ 165
+ + +GLDLE S ++ + F + Q G F+IFVKSWS + P+
Sbjct: 66 KVEHPVE-MGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124
Query: 166 IATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEE---- 221
+ +LSSSLY+R TS + M++ A FLK K + E P + V +E
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPK----ILEEGPFHKIHKGVYQELPNS 180
Query: 222 --SNMEALAADF-FNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFAN 278
++ + AD F + L Y E L F ES VE K FST+ + + +P+YV AFAN
Sbjct: 181 DPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFAN 240
Query: 279 TDGGYLFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFL 337
T GGYLF+G+++ +EV+G E L + +I KLP HFC + I + K +
Sbjct: 241 TGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIV 300
Query: 338 GVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEE 397
V +G L GY +RV FCCAVF++ P+SW V+D V LT ++W+ M D++P +
Sbjct: 301 NVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQ 360
Query: 398 LPSPASTSSPVSQSYPLREYINFK--------IQPLRYHLPGLSEKITCAPKTFCRNLFS 449
L +S PL + K +Q L + +P + T P++ R+L S
Sbjct: 361 LSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYT--PESLWRDLIS 418
Query: 450 QHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMV 509
+H GL++LI ++M +G LIFSRSW++DL LQE V+CDALLI+Q+ P+LYT
Sbjct: 419 EHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
Query: 510 QDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPES 569
QD E +DY T+TA TLKQKL +GGYT KVCV K+ LSPE S + YP S
Sbjct: 479 QDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPAS 538
Query: 570 YYWTTAQTMKDLEKALSNIL 589
Y Q M+ L ++L +L
Sbjct: 539 YSLAGTQHMEALLQSLVIVL 558
Score = 69.3 bits (168), Expect = 1e-11
Identities = 36/51 (70%), Positives = 38/51 (74%), Gaps = 10/51 (19%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI----------RKEFLRGN 41
MAMKIMEKIRNVFHCEAHRILY+CE+Q LRNFI RK FLR N
Sbjct: 608 MAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKTFLREN 658
>gi|157388959 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 346 bits (888), Expect = 3e-95
Identities = 221/560 (39%), Positives = 311/560 (55%), Gaps = 35/560 (6%)
Query: 54 LDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENK 113
++ +Y +LV+NVG VTLGE NRKK++ Q R Q+ E V RA CALLNSGGGVI+ K
Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMA---K 65
Query: 114 GYSYKKDGIGLDLENSFSNMLPF--VPNFLDFMQNGNYFHIFVKSWSL------ETSGPQ 165
+ + +GLDLE S ++ + F + Q G F+IFVKSWS + P+
Sbjct: 66 KVEHPVE-MGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124
Query: 166 IATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEE---- 221
+ +LSSSLY+R TS + M++ A FLK K + E P + V +E
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPK----ILEEGPFHKIHKGVYQELPNS 180
Query: 222 --SNMEALAADF-FNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFAN 278
++ + AD F + L Y E L F ES VE K FST+ + + +P+YV AFAN
Sbjct: 181 DPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFAN 240
Query: 279 TDGGYLFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFL 337
T GGYLF+G+++ +EV+G E L + +I KLP HFC + I + K +
Sbjct: 241 TGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIV 300
Query: 338 GVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEE 397
V +G L GY +RV FCCAVF++ P+SW V+D V LT ++W+ M D++P +
Sbjct: 301 NVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQ 360
Query: 398 LPSPASTSSPVSQSYPLREYINFK--------IQPLRYHLPGLSEKITCAPKTFCRNLFS 449
L +S PL + K +Q L + +P + T P++ R+L S
Sbjct: 361 LSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYT--PESLWRDLIS 418
Query: 450 QHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMV 509
+H GL++LI ++M +G LIFSRSW++DL LQE V+CDALLI+Q+ P+LYT
Sbjct: 419 EHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
Query: 510 QDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPES 569
QD E +DY T+TA TLKQKL +GGYT KVCV K+ LSPE S + YP S
Sbjct: 479 QDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPAS 538
Query: 570 YYWTTAQTMKDLEKALSNIL 589
Y Q M+ L ++L +L
Sbjct: 539 YSLAGTQHMEALLQSLVIVL 558
Score = 69.3 bits (168), Expect = 1e-11
Identities = 36/51 (70%), Positives = 38/51 (74%), Gaps = 10/51 (19%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI----------RKEFLRGN 41
MAMKIMEKIRNVFHCEAHRILY+CE+Q LRNFI RK FLR N
Sbjct: 608 MAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKTFLREN 658
>gi|157388957 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 346 bits (888), Expect = 3e-95
Identities = 221/560 (39%), Positives = 311/560 (55%), Gaps = 35/560 (6%)
Query: 54 LDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEVENK 113
++ +Y +LV+NVG VTLGE NRKK++ Q R Q+ E V RA CALLNSGGGVI+ K
Sbjct: 10 VEPSYPDLVINVGEVTLGEENRKKLQKIQ-RDQEKERVMRAACALLNSGGGVIRMA---K 65
Query: 114 GYSYKKDGIGLDLENSFSNMLPF--VPNFLDFMQNGNYFHIFVKSWSL------ETSGPQ 165
+ + +GLDLE S ++ + F + Q G F+IFVKSWS + P+
Sbjct: 66 KVEHPVE-MGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPEDRSVKPR 124
Query: 166 IATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEE---- 221
+ +LSSSLY+R TS + M++ A FLK K + E P + V +E
Sbjct: 125 LCSLSSSLYRRSETSVRSMDSREAFCFLKTKRKPK----ILEEGPFHKIHKGVYQELPNS 180
Query: 222 --SNMEALAADF-FNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFAN 278
++ + AD F + L Y E L F ES VE K FST+ + + +P+YV AFAN
Sbjct: 181 DPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEYVPAFAN 240
Query: 279 TDGGYLFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFL 337
T GGYLF+G+++ +EV+G E L + +I KLP HFC + I + K +
Sbjct: 241 TGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPITFTLKIV 300
Query: 338 GVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEE 397
V +G L GY +RV FCCAVF++ P+SW V+D V LT ++W+ M D++P +
Sbjct: 301 NVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDTDPDLLQ 360
Query: 398 LPSPASTSSPVSQSYPLREYINFK--------IQPLRYHLPGLSEKITCAPKTFCRNLFS 449
L +S PL + K +Q L + +P + T P++ R+L S
Sbjct: 361 LSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYT--PESLWRDLIS 418
Query: 450 QHEGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMV 509
+H GL++LI ++M +G LIFSRSW++DL LQE V+CDALLI+Q+ P+LYT
Sbjct: 419 EHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
Query: 510 QDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPES 569
QD E +DY T+TA TLKQKL +GGYT KVCV K+ LSPE S + YP S
Sbjct: 479 QDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPAS 538
Query: 570 YYWTTAQTMKDLEKALSNIL 589
Y Q M+ L ++L +L
Sbjct: 539 YSLAGTQHMEALLQSLVIVL 558
Score = 69.3 bits (168), Expect = 1e-11
Identities = 36/51 (70%), Positives = 38/51 (74%), Gaps = 10/51 (19%)
Query: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI----------RKEFLRGN 41
MAMKIMEKIRNVFHCEAHRILY+CE+Q LRNFI RK FLR N
Sbjct: 608 MAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKTFLREN 658
>gi|45267821 schlafen-like 1 [Homo sapiens]
Length = 407
Score = 33.1 bits (74), Expect = 0.78
Identities = 18/53 (33%), Positives = 29/53 (54%)
Query: 246 TESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGGYLFVGLNEDKEVIGFK 298
+E+ ++E K S E L + +YV AF N++GG L VG+ + V G +
Sbjct: 220 SETRNMEFKRGSGEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIR 272
>gi|224586875 coiled-coil domain containing 65 [Homo sapiens]
Length = 484
Score = 32.0 bits (71), Expect = 1.7
Identities = 37/170 (21%), Positives = 68/170 (40%), Gaps = 21/170 (12%)
Query: 169 LSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEESNMEALA 228
L S L+ D A + + LE +ME L EF +R + Q E + L
Sbjct: 117 LRSHLHNVDQLLALQRHRLSLLEESYNMELEA----LTKEFETERKTIIDQHEKEIHYLQ 172
Query: 229 ADFF----NRTELGYKEKLTFT------ESTHVEIKNF-------STEKLLQRITEILPQ 271
F N + Y+ KL F ++ ++E K+F E L ++ ++L
Sbjct: 173 DIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKN 232
Query: 272 YVSAFANTDGGYLFVGLNEDKEVIGFKAEKSYLTKLEEVTKNSIGKLPVH 321
Y A + + + + ++K + + + KL++ S GK+ +H
Sbjct: 233 YTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIH 282
>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
Length = 377
Score = 31.6 bits (70), Expect = 2.3
Identities = 17/56 (30%), Positives = 25/56 (44%)
Query: 542 MTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTTAQTMKDLEKALSNILPKENQIFL 597
+ K+ SPE SC + S VIYP + A ++ +SN E + FL
Sbjct: 77 LVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPISNSRTDEREFFL 132
>gi|7661556 TruB pseudouridine (psi) synthase homolog 2 [Homo
sapiens]
Length = 331
Score = 31.6 bits (70), Expect = 2.3
Identities = 35/147 (23%), Positives = 65/147 (44%), Gaps = 18/147 (12%)
Query: 452 EGLKQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYT----FH 507
E L +++ GS K +++S +LDL QE +++ L+ +K P+L T +
Sbjct: 159 EKLDRILAVIQGSHQKALVMYS---NLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLY 215
Query: 508 MVQDEEFKDYST--QTAQTLKQKLAKIGGYTKKVCVMTKI------FYLSPEGKTSCQYD 559
E + +T + L++ + +IG K V T++ F+ Q+D
Sbjct: 216 FAPPEFLLEVQCMHETQKELRKLVHEIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQWD 275
Query: 560 LNSQVIYPESYYWTTAQTMKDLEKALS 586
L + ++ T Q +LEK+LS
Sbjct: 276 LTN---IQDAIRAATPQVAAELEKSLS 299
>gi|29789401 ubiquitin-conjugating enzyme E2Q 2 isoform 1 [Homo
sapiens]
Length = 375
Score = 30.4 bits (67), Expect = 5.0
Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 11/113 (9%)
Query: 349 VYALRVE-RFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEPVCEELPSPASTSSP 407
V L+ E +F ++F K + + + ++ +L QF+V + LP P +
Sbjct: 3 VSGLKAELKFLASIFDKNHERFRIVSWKLDELH----CQFLVPQQGSPHSLPPPLTLHCN 58
Query: 408 VSQSYPLREYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGLKQLICE 460
+++SYP I F + P L+ + T NL Q LK LICE
Sbjct: 59 ITESYPSSSPIWF----VDSEDPNLTSVLERLEDTKNNNLLRQQ--LKWLICE 105
>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
Length = 1170
Score = 30.4 bits (67), Expect = 5.0
Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 10/122 (8%)
Query: 432 LSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDL-GLQENHKVLC 490
+ E I K+ R++ +G K I E G+V GS+ +R W DL G+Q +H
Sbjct: 106 IEEMINNRNKSVVRSMSWNADGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLSH---- 161
Query: 491 DALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSP 550
+ S D +L+ + + E Y Q +K KL+ + T + + +Y
Sbjct: 162 --VTWSADSKVLLFG---MANGEIHIYDNQGNFMIKMKLSCLVNVTGAISIAGIHWYHGT 216
Query: 551 EG 552
EG
Sbjct: 217 EG 218
>gi|4507247 SH3 and cysteine rich domain [Homo sapiens]
Length = 402
Score = 30.4 bits (67), Expect = 5.0
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 396 EELPSPASTSSPVSQSYPLREYINFKIQPLR 426
E+ PSPASTSS S+ L+ ++FK + LR
Sbjct: 23 EQPPSPASTSSQESKLQKLKRSLSFKTKSLR 53
>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
Length = 1181
Score = 30.4 bits (67), Expect = 5.0
Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 10/122 (8%)
Query: 432 LSEKITCAPKTFCRNLFSQHEGLKQLICEEMGSVNKGSLIFSRSWSLDL-GLQENHKVLC 490
+ E I K+ R++ +G K I E G+V GS+ +R W DL G+Q +H
Sbjct: 106 IEEMINNRNKSVVRSMSWNADGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLSH---- 161
Query: 491 DALLISQDKPPVLYTFHMVQDEEFKDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSP 550
+ S D +L+ + + E Y Q +K KL+ + T + + +Y
Sbjct: 162 --VTWSADSKVLLFG---MANGEIHIYDNQGNFMIKMKLSCLVNVTGAISIAGIHWYHGT 216
Query: 551 EG 552
EG
Sbjct: 217 EG 218
>gi|70995130 cholinergic receptor, nicotinic, alpha 9 precursor
[Homo sapiens]
Length = 479
Score = 30.0 bits (66), Expect = 6.6
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 330 INYLCKFLGVYDKGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMV 389
+ Y+ + L VYD G C + R V++K P+S ++K R K L+ K+ + +
Sbjct: 342 LKYMSRVLFVYDVGESCLSPHHSRERDHLTKVYSKLPES-NLKAARNKDLSRKKDMNKRL 400
Query: 390 DSEPVCEELPSPASTSSPVSQSYPLREYINFKIQPLRYH 428
++ C+ +P S +Q L I + + L+ H
Sbjct: 401 KNDLGCQG-KNPQEAESYCAQYKVLTRNIEYIAKCLKDH 438
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,989,696
Number of Sequences: 37866
Number of extensions: 1029914
Number of successful extensions: 2734
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2661
Number of HSP's gapped (non-prelim): 28
length of query: 617
length of database: 18,247,518
effective HSP length: 108
effective length of query: 509
effective length of database: 14,157,990
effective search space: 7206416910
effective search space used: 7206416910
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.