Guide to the Human Genome
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Search of human proteins with 222418633

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222418633 family with sequence similarity 71, member B [Homo
sapiens]
         (605 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222418633 family with sequence similarity 71, member B [Homo ...  1187   0.0  
gi|23957696 hypothetical protein LOC149647 [Homo sapiens]             503   e-142
gi|23503301 hypothetical protein LOC196472 [Homo sapiens]             241   1e-63
gi|89363024 hypothetical protein LOC161142 [Homo sapiens]             117   3e-26
gi|76253859 hypothetical protein LOC112703 [Homo sapiens]              98   2e-20
gi|223972704 hypothetical protein LOC284418 [Homo sapiens]             92   1e-18
gi|14211935 testes development-related NYD-SP18 [Homo sapiens]         84   3e-16
gi|193083150 hypothetical protein LOC346653 isoform b [Homo sapi...    84   4e-16
gi|149192824 hypothetical protein LOC346653 isoform a [Homo sapi...    76   8e-14
gi|161016767 mucin 21 [Homo sapiens]                                   64   5e-10
gi|57864582 hornerin [Homo sapiens]                                    61   3e-09
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]             56   1e-07
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...    56   1e-07
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...    55   1e-07
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    52   1e-06
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    52   1e-06
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    52   2e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         50   8e-06
gi|60097902 filaggrin [Homo sapiens]                                   49   2e-05
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]     49   2e-05
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]     49   2e-05

>gi|222418633 family with sequence similarity 71, member B [Homo
           sapiens]
          Length = 605

 Score = 1187 bits (3070), Expect = 0.0
 Identities = 605/605 (100%), Positives = 605/605 (100%)

Query: 1   MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60
           MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV
Sbjct: 1   MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60

Query: 61  IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120
           IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT
Sbjct: 61  IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120

Query: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180
           RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE
Sbjct: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180

Query: 181 SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA 240
           SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA
Sbjct: 181 SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA 240

Query: 241 SHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIAT 300
           SHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIAT
Sbjct: 241 SHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIAT 300

Query: 301 TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM 360
           TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM
Sbjct: 301 TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM 360

Query: 361 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420
           AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP
Sbjct: 361 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420

Query: 421 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480
           SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK
Sbjct: 421 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480

Query: 481 KEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRS 540
           KEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRS
Sbjct: 481 KEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRS 540

Query: 541 LRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVF 600
           LRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVF
Sbjct: 541 LRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVF 600

Query: 601 ETKSI 605
           ETKSI
Sbjct: 601 ETKSI 605


>gi|23957696 hypothetical protein LOC149647 [Homo sapiens]
          Length = 594

 Score =  503 bits (1295), Expect = e-142
 Identities = 300/612 (49%), Positives = 396/612 (64%), Gaps = 31/612 (5%)

Query: 1   MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60
           M+ +  LPYYTA S SSMS F T+MG LQRQLY +GEY+IFKYAP+FES+FIQI K+GEV
Sbjct: 1   MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLY-KGEYDIFKYAPIFESDFIQITKRGEV 59

Query: 61  IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120
           IDVHNRVRMVT+GI  TSPILPLPDVM+LA+P   CE++   G+  K + R+  K LELT
Sbjct: 60  IDVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELT 119

Query: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180
           RLLPL+FV+IS+ DHEKQQLRLK ATGR+ YLQLCP+ DTR+DLF YWEKL+YLLRPP+E
Sbjct: 120 RLLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPME 179

Query: 181 SYCSTPTLLSGDAP-----PEDNKSLVAAELHREGDQSET---GLYKPCDVSAATSSAYA 232
           S  ST  + + D        ED +SL A  L  +GDQ +     L+   +V  ATS+AYA
Sbjct: 180 SNSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYA 239

Query: 233 GGEGIQHASH---GTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAM 289
           GGEG+Q+  +      +A+ P TST  A E       GG+  A  A       A AGAA 
Sbjct: 240 GGEGLQNDFNKPTNVLNASIPKTSTELAEE----PATGGIKEAAAAG------AAAGAAT 289

Query: 290 SPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAA 349
               GA+S+A   SA PGQV+ A+AGAA  + G N+ + ++AG A+++     +A+ GAA
Sbjct: 290 GTVAGALSVAAANSA-PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAA 348

Query: 350 STSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMS 409
             S E  S++   + SLS++ S+S A AG + TS+ AAE     A GP +ST QS+  +S
Sbjct: 349 GKSSEHVSSA---SMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLS 405

Query: 410 ERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRS 469
            + G ++ +Q SAE   E +ERRE KDR   R SSH R+ GES  +  GDK  + SS RS
Sbjct: 406 GQHGRER-TQASAEGCKEGRERRE-KDRALGR-SSHRRRTGESRHKTRGDKIAQKSSSRS 462

Query: 470 ASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQK 529
           +  H+  RDDKKEKG  N    RH  S K  +H+   KESRT+ + G++   +S+G+  K
Sbjct: 463 SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGS-SK 521

Query: 530 KASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGT 589
              ++SSFLR++RA   +K   T H R+VD++AKM E+    A  E A+GGQ LEM+ G+
Sbjct: 522 GLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMV-GS 580

Query: 590 MTSEKTEMIVFE 601
           MT +  E + FE
Sbjct: 581 MTPDIMETVTFE 592


>gi|23503301 hypothetical protein LOC196472 [Homo sapiens]
          Length = 241

 Score =  241 bits (616), Expect = 1e-63
 Identities = 124/191 (64%), Positives = 148/191 (77%), Gaps = 4/191 (2%)

Query: 4   ESC--LPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVI 61
           E C  LPYYTA S  +M  F TSMG LQRQLY +GEY IF+YAPMFES+FIQI+K+GEVI
Sbjct: 2   EDCCMLPYYTAQSSPAMGMFNTSMGKLQRQLY-KGEYTIFRYAPMFESDFIQISKRGEVI 60

Query: 62  DVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTR 121
           DVHNR RMVT+GIV TSP L LPDVM+LA+P  +C+ + R G   + R   P + LELTR
Sbjct: 61  DVHNRARMVTMGIVRTSPCLTLPDVMLLARPAAVCD-NARCGPATQKRESPPAEILELTR 119

Query: 122 LLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVES 181
           LLPL FVKI+IH+  K+QL LKLATGR+FYLQLCP SD  EDLF +WE LVY+LRPPVE+
Sbjct: 120 LLPLMFVKITIHNSVKKQLHLKLATGRSFYLQLCPPSDASEDLFVHWENLVYILRPPVEA 179

Query: 182 YCSTPTLLSGD 192
           Y  T  +L+G+
Sbjct: 180 YSDTRAILAGN 190


>gi|89363024 hypothetical protein LOC161142 [Homo sapiens]
          Length = 422

 Score =  117 bits (293), Expect = 3e-26
 Identities = 67/149 (44%), Positives = 90/149 (60%), Gaps = 2/149 (1%)

Query: 27  DLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDV 86
           DLQ  L + GEY  F   PM ESNFIQ+N++GE I +HNR   VTVGI  +S    +P+V
Sbjct: 28  DLQNML-DGGEYAPFVSPPMLESNFIQVNRRGESIYLHNRANWVTVGICFSSSTHKIPNV 86

Query: 87  MVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLAT 146
           M+LA  T   ++      F       P + L LTR LPL+FV +S+HD E   L++KL +
Sbjct: 87  MLLAHLTPGAQKDTET-LFKSLLTSPPAEKLVLTRFLPLQFVTLSVHDAENMSLKVKLVS 145

Query: 147 GRTFYLQLCPSSDTREDLFCYWEKLVYLL 175
           GR +YLQLC S+  ++ LF  W  L+ LL
Sbjct: 146 GRAYYLQLCTSAYKQDTLFSQWVALISLL 174


>gi|76253859 hypothetical protein LOC112703 [Homo sapiens]
          Length = 231

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 62/149 (41%), Positives = 86/149 (57%), Gaps = 25/149 (16%)

Query: 28  LQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVM 87
           LQR L + GE++ F+  P+FESNF+Q+ + GEV +       VT+G+  +SP L LPD++
Sbjct: 96  LQRYLQS-GEFDQFRDFPIFESNFVQVTRLGEVANE------VTMGVAASSPALELPDLL 148

Query: 88  VLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLATG 147
           +LA P             AK  G      L+L  L PLKFV++ +HD  + QL +KL T 
Sbjct: 149 LLAGP-------------AKENGH-----LQLFGLFPLKFVQLFVHDKSRCQLEVKLNTS 190

Query: 148 RTFYLQLCPSSDTREDLFCYWEKLVYLLR 176
           RTFYLQL     TR+  F  W +L+Y LR
Sbjct: 191 RTFYLQLRAPLKTRDREFGQWVRLLYRLR 219


>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
          Length = 922

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 52/163 (31%), Positives = 87/163 (53%), Gaps = 17/163 (10%)

Query: 25  MGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLP 84
           +G+LQ+ L  +GEY   +  PMFESNF+Q+  +G  + V++R   + +G+  + P L LP
Sbjct: 23  LGELQKTL-QKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLP 81

Query: 85  DVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKL 144
           D++++ QP +                 R    L LTR++PL  V + +HD    +L+L+L
Sbjct: 82  DILLIGQPAE----------------DRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRL 125

Query: 145 ATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVESYCSTPT 187
            +GR +YL L    +    LF  W +L+ LL+ P  ++    T
Sbjct: 126 VSGRQYYLALDAPDNEVGFLFHCWVRLINLLQEPAPTWTPRTT 168


>gi|14211935 testes development-related NYD-SP18 [Homo sapiens]
          Length = 344

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 48/155 (30%), Positives = 86/155 (55%), Gaps = 12/155 (7%)

Query: 37  EYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKIC 96
           E+N+F  + +FESNFIQ+ +     DV+     + +G+  + P LPLP+++++A      
Sbjct: 67  EFNLFLDSVVFESNFIQVKRGRNWRDVYKASNTMALGVTSSVPCLPLPNILLMAS----- 121

Query: 97  EQHVRWGRFAKGRGRRP--VKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQL 154
              V+W +       RP     + L R+LPL+FV++ + DH ++ L+L+  T + +YL+L
Sbjct: 122 ---VKWHQGQNQTWNRPSIAPNIFLKRILPLRFVELQVCDHYQRILQLRTVTEKIYYLKL 178

Query: 155 CPSSDTREDLFCYWEKLVYLLRPPVESYCSTPTLL 189
            P  D  E +F +W +LV +L+  +      P +L
Sbjct: 179 HP--DHPETVFHFWIRLVQILQKGLSITTKDPRIL 211


>gi|193083150 hypothetical protein LOC346653 isoform b [Homo
           sapiens]
          Length = 300

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 52/146 (35%), Positives = 83/146 (56%), Gaps = 8/146 (5%)

Query: 31  QLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVMVLA 90
           QL +  E+N+F  + +FESNFIQ+ K G   DV      V +G+  + P LPLP+V+++A
Sbjct: 29  QLIHSPEFNLFSNSVVFESNFIQVTKPGNWRDVCEGSATVILGVTSSVPSLPLPNVLLMA 88

Query: 91  QPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTF 150
             T        W       G  PV  + L+RLLPLK+V++ I+D  ++ LR++  T + +
Sbjct: 89  NVTWPQGPFTTWST----PGDAPV--INLSRLLPLKYVELRIYDRLQRILRVRTVTEKIY 142

Query: 151 YLQLCPSSDTREDLFCYWEKLVYLLR 176
           YL+L       E +F +W +LV +L+
Sbjct: 143 YLKL--HEKHPEIVFQFWVRLVKILQ 166


>gi|149192824 hypothetical protein LOC346653 isoform a [Homo
           sapiens]
          Length = 309

 Score = 76.3 bits (186), Expect = 8e-14
 Identities = 52/155 (33%), Positives = 83/155 (53%), Gaps = 17/155 (10%)

Query: 31  QLYNRGEYNIFKYAPMFESNFIQ---------INKKGEVIDVHNRVRMVTVGIVCTSPIL 81
           QL +  E+N+F  + +FESNFIQ         + K G   DV      V +G+  + P L
Sbjct: 29  QLIHSPEFNLFSNSVVFESNFIQTHVPEADFQVTKPGNWRDVCEGSATVILGVTSSVPSL 88

Query: 82  PLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLR 141
           PLP+V+++A  T        W       G  PV  + L+RLLPLK+V++ I+D  ++ LR
Sbjct: 89  PLPNVLLMANVTWPQGPFTTWST----PGDAPV--INLSRLLPLKYVELRIYDRLQRILR 142

Query: 142 LKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLR 176
           ++  T + +YL+L       E +F +W +LV +L+
Sbjct: 143 VRTVTEKIYYLKL--HEKHPEIVFQFWVRLVKILQ 175


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 77/365 (21%), Positives = 143/365 (39%), Gaps = 19/365 (5%)

Query: 184 STPTLLSGDAPPEDNKSLVA-AELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASH 242
           ST T+ SG +   +  S+V  +E H       T         ++  S     E     S 
Sbjct: 58  STATI-SGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSES-STTSS 115

Query: 243 GTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTK 302
           G ++A +  +STP +    A  +      +G +T   +D +   +  S AT + S  T+ 
Sbjct: 116 GASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSS 175

Query: 303 SAGPG---QVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359
            A      + +T  + A+     E+ ++ S A  A  +SE  + +     +T+ E ++TS
Sbjct: 176 GASTATNSESSTVSSRASTATNSESSTTSSGASTAT-NSESRTTSNGAGTATNSESSTTS 234

Query: 360 MAGAASLSQDSSLSAAFAGSITTSKCA--------AERTEGPAVGPLISTLQSEGYMSER 411
              + + + +SS  ++ AG+ T S+ +        A  +E   V   IST+ +    +  
Sbjct: 235 SGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPS 294

Query: 412 DGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSAS 471
            G+   +   +   +         D   +   +      ES    +G      S   + S
Sbjct: 295 SGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTS 354

Query: 472 GHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKA 531
              +T  +      S+  G    ++ +SST SS    + TT E     S +ST A   ++
Sbjct: 355 SGASTATNSGSSTTSS--GTSTATNSESSTVSS-GASTATTSESSTTSSGAST-ATNSES 410

Query: 532 SKISS 536
           S +SS
Sbjct: 411 STVSS 415



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 75/338 (22%), Positives = 129/338 (38%), Gaps = 22/338 (6%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283
           S+  S+A         +   TA+ +  ST++ GA+    + ++   + A TAT   +   
Sbjct: 144 SSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTT 203

Query: 284 IAGAAMSPATGAMSIATTKSAGP---GQVTTALAGAAIKNPGENESSKSMAGAA-----N 335
            +GA  S AT + S  T+  AG     + +T  +GA+     E+ +  S AG A     +
Sbjct: 204 SSGA--STATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESS 261

Query: 336 ISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAV 395
            +S G   A    +ST   G ST     +S     + +A  + S TTS  A   T   + 
Sbjct: 262 TTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDS- 320

Query: 396 GPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRR 455
               ST  S    +    S   S  ++   N             +   S    +G S   
Sbjct: 321 ----STTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTA- 375

Query: 456 RAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQEL 515
                N ++S+  S +    T +       ++       S+  S   ++T  ES TT   
Sbjct: 376 ----TNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSS- 430

Query: 516 GKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTS 553
           G N +A+++G+    A   ++ L  +  T  S +   S
Sbjct: 431 GAN-TATNSGSSVTSAGSGTAALTGMHTTSHSASTAVS 467



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 14/221 (6%)

Query: 181 SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA 240
           S  STP+  +G A   ++ +  +        +S T       V+ + SS  + G      
Sbjct: 243 SESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATN 302

Query: 241 SHG--------TASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPA 292
           S          TA+ +  ST++ GA+    + ++   + A TAT   +    +GA+ +  
Sbjct: 303 SESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATN 362

Query: 293 TGAMSIAT-TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANIS-----SEGISLALV 346
           +G+ + ++ T +A   + +T  +GA+     E+ ++ S A  A  S     S G S A  
Sbjct: 363 SGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATN 422

Query: 347 GAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
             +ST+  G +T+    +S++   S +AA  G  TTS  A+
Sbjct: 423 SESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSAS 463



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 49/285 (17%), Positives = 94/285 (32%), Gaps = 29/285 (10%)

Query: 326 SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQ------DSSLSAAFAGS 379
           SS   +GA+  ++ G S+   G ++ ++ G+S +  G + ++        S +S A    
Sbjct: 35  SSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSE 94

Query: 380 ITTSKCA---AERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKD 436
            +T       A  +E        ST  +    +   G+   +   +   +         D
Sbjct: 95  FSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSD 154

Query: 437 RHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSS 496
              +   +      ES    +G      S   + S   +T  + +             S+
Sbjct: 155 SSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSE------------SST 202

Query: 497 RKSSTHSSTKKESRTTQE-----LGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRV 551
             S   ++T  ESRTT            S +S+GA     S+ S+          S++  
Sbjct: 203 TSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESST 262

Query: 552 TSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTE 596
           TS        A   E   + + +      +     SG  T+  +E
Sbjct: 263 TSSGAG---TATNSESSTVSSGISTVTNSESSTPSSGANTATNSE 304


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 79/317 (24%), Positives = 120/317 (37%), Gaps = 28/317 (8%)

Query: 224  SAATSSAYAG-GEGIQHAS----HGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGP 278
            S+  SS Y   G G  H+S    HG+ S  S  +   G++ G ++      + +  + G 
Sbjct: 937  SSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGH 996

Query: 279  RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
                + +G + SP+ G     + +S+  G   +    ++ + P E+ S  S       S 
Sbjct: 997  GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESR 1056

Query: 339  EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPL 398
             G S       S+S  G S++     S S  SS       S   S    +   G +    
Sbjct: 1057 SGQSSGYGQHGSSS--GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS---- 1110

Query: 399  ISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS---RKSS---HHRKAGES 452
                QS GY   R GS     P          +     RH S   R SS   H    GES
Sbjct: 1111 ----QSSGY--GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGES 1164

Query: 453  ----HRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE 508
                H   +  ++   S H S SGH +       +   + RG+RHGSS  SS+H   +  
Sbjct: 1165 SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG-QHG 1223

Query: 509  SRTTQELGKNQSASSTG 525
            S + Q  G  +  S +G
Sbjct: 1224 SGSRQSSGHGRQGSGSG 1240



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 78/330 (23%), Positives = 116/330 (35%), Gaps = 35/330 (10%)

Query: 207  HREGDQSETGLYKPCDVSAATSSAYAG-GEGIQHASHGTASAASPSTSTPGAAEGGAART 265
            H E    ++  Y      +  SS Y   G     +S G    +S  +S+     G  +R 
Sbjct: 1169 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 1228

Query: 266  AGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENE 325
            + G    G+ +G            SP+ G        S+  GQ  +    ++ + P E+ 
Sbjct: 1229 SSGHGRQGSGSGH-----------SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1277

Query: 326  SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC 385
            S  S     + S  G S A     S S  G   S     S S  SS       S   S  
Sbjct: 1278 SGHSSVFGQHESGSGHSSAYSQHGSGS--GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1335

Query: 386  AAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS----- 440
               R  G +        QS GY   R G+     PS               +H S     
Sbjct: 1336 YGHRGSGSS--------QSSGY--GRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 1385

Query: 441  RKSSHH-----RKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGS 495
              S  H     + +G  H   +  ++   + H S SGH ++ +    +   + RG+RHGS
Sbjct: 1386 SSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGS 1445

Query: 496  SRKSSTHSSTKKESRTTQELGKNQSASSTG 525
            S  SS+ S  +  S + Q LG  Q  S +G
Sbjct: 1446 SSGSSS-SYGQHGSGSRQSLGHGQHGSGSG 1474



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 78/317 (24%), Positives = 121/317 (38%), Gaps = 30/317 (9%)

Query: 224  SAATSSAYAG-GEGIQHAS----HGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGP 278
            S+  SS+Y+  G G  H+S    HG+ S  S      G++ G ++R   G   +G+    
Sbjct: 2113 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY--GQHGSGSRQSS 2170

Query: 279  RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
                  +G+  SP+ G     +  S+  GQ  +    ++ + P E+ S  S     + S 
Sbjct: 2171 GHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 2230

Query: 339  EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPL 398
             G S A     S S  G   S     S S  SS       S   S    +   G +    
Sbjct: 2231 SGHSSAYSQHGSGS--GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS---- 2284

Query: 399  ISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS-----RKSSHH-----RK 448
                QS  Y  +  GS +   PS               +H S       S  H     + 
Sbjct: 2285 ----QSSSYGQQGSGSGQ--SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 2338

Query: 449  AGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE 508
            +G  H   +  ++   + H S SGH ++ +    +   + RG+RHGSS  SS+ S  +  
Sbjct: 2339 SGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSS-SYGQHG 2397

Query: 509  SRTTQELGKNQSASSTG 525
            S + Q LG  Q  S +G
Sbjct: 2398 SGSRQSLGHGQHGSGSG 2414



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 70/294 (23%), Positives = 110/294 (37%), Gaps = 29/294 (9%)

Query: 232  AGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSP 291
            + G    +  HG+ S  S      G+  G +   + G   +G+          +G+  S 
Sbjct: 2386 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSS 2445

Query: 292  ATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST 351
            + G     +  S+G G               E+ S +S     + SS G S       ST
Sbjct: 2446 SRGPYESGSGHSSGLGH-------------RESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492

Query: 352  SLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSER 411
            S + +S    GA+S  Q SS     +GS   S+ +    +G   G      QS G+    
Sbjct: 2493 SGQSSSCGQHGASS-GQSSSHGQHGSGS---SQSSGYGRQGSGSG------QSPGHGQRG 2542

Query: 412  DGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSAS 471
             GS++   PS         R     +H S        +G  H   +  ++   S H S S
Sbjct: 2543 SGSRQ--SPSYGRHGSGSGRSSSSGQHGSGLGE---SSGFGHHESSSGQSSSYSQHGSGS 2597

Query: 472  GHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTG 525
            GH +       +   + RG+RHGSS  SS+H   +  S + Q  G  +  S +G
Sbjct: 2598 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG-QHGSGSRQSSGHGRQGSGSG 2650



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 72/297 (24%), Positives = 112/297 (37%), Gaps = 34/297 (11%)

Query: 232  AGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSP 291
            + G    +  HG+ S  S      G+  G +   + G   +G+          +G+  S 
Sbjct: 1446 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSS 1505

Query: 292  ATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST 351
            + G     ++ S+G G               E+ S +S     + SS G S       ST
Sbjct: 1506 SRGPYESGSSHSSGLGH-------------RESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552

Query: 352  SLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSER 411
            S + +S    GA+S  Q SS     +GS   S+ +    +G   G      QS G+    
Sbjct: 1553 SGQSSSCGQHGASS-GQSSSHGQHGSGS---SQSSGYGRQGSGSG------QSPGHGQRG 1602

Query: 412  DGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSAS 471
             GS++   PS         R     +H S        +G  H   +  ++   S H S S
Sbjct: 1603 SGSRQ--SPSYGRHGSGSGRSSSSGQHGSGLGE---SSGFGHHESSSGQSSSYSQHGSGS 1657

Query: 472  GHKNTRDDKKEKGYSNVRGKRHGSSRKSST----HSSTKKES--RTTQELGKNQSAS 522
            GH +       +   + RG+RHGSS +SS+    H S  ++S     Q  G  QS S
Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPS 1714



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 75/330 (22%), Positives = 116/330 (35%), Gaps = 35/330 (10%)

Query: 207  HREGDQSETGLYKPCDVSAATSSAYAG-GEGIQHASHGTASAASPSTSTPGAAEGGAART 265
            H E    ++  Y      +  SS Y   G     +S G    +S  +S+     G  +R 
Sbjct: 1639 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQ 1698

Query: 266  AGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENE 325
            + G    G+ +G            SP+ G        S+  GQ  +    ++ + P E+ 
Sbjct: 1699 SSGHGRQGSGSG-----------QSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1747

Query: 326  SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC 385
            S  S     + S  G S A     S S  G   S     S S  SS       S   S  
Sbjct: 1748 SGHSSVFGQHESGSGHSSAYSQHGSGS--GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805

Query: 386  AAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS----- 440
              +   G +        QS  Y  +  GS +   PS               +H S     
Sbjct: 1806 HGQHGSGSS--------QSSSYGQQGSGSGQ--SPSRGRHGSGSGHSSSYGQHGSGSGWS 1855

Query: 441  RKSSHH-----RKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGS 495
              S  H     + +G  H   +  ++   + H S SGH ++ +    +   + RG++HGS
Sbjct: 1856 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGS 1915

Query: 496  SRKSSTHSSTKKESRTTQELGKNQSASSTG 525
            S  SS+ S  +  S + Q LG  Q  S +G
Sbjct: 1916 SSGSSS-SYGQHGSGSRQSLGHGQHGSGSG 1944



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 73/312 (23%), Positives = 112/312 (35%), Gaps = 23/312 (7%)

Query: 224  SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283
            S  T      G    +  HG+ S  S      G++ G ++      + +  + G     +
Sbjct: 1882 SGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1941

Query: 284  IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISL 343
             +G + SP+ G     + +S+  G   +    ++ + P E+ S  S       S  G S 
Sbjct: 1942 GSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS 2001

Query: 344  ALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQ 403
                  S+S  G S++     S S  SS       S   S    +   G +        Q
Sbjct: 2002 GYGQHGSSS--GHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS--------Q 2051

Query: 404  SEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS---RKSS---HHRKAGES----H 453
            S GY   R GS     P          +     RH S   R SS   H    GES    H
Sbjct: 2052 SSGY--GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGH 2109

Query: 454  RRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQ 513
               +  ++   S H S SGH +       +   + RG+RHGSS  SS+    +  S + Q
Sbjct: 2110 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYG-QHGSGSRQ 2168

Query: 514  ELGKNQSASSTG 525
              G  +  S +G
Sbjct: 2169 SSGHGRQGSGSG 2180



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 76/336 (22%), Positives = 127/336 (37%), Gaps = 31/336 (9%)

Query: 205 ELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHAS----HGTAS----------AASP 250
           + H  G    +G  +    S  +S     G G  H+S    HG+ S          ++S 
Sbjct: 219 DTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSG 278

Query: 251 STSTPGAAEGGAARTAG-GMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQV 309
           S+S+ G    G+ ++ G G   +G+   P      +G+  S + G     ++ S   G  
Sbjct: 279 SSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHY 338

Query: 310 TTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQD 369
            +          G++ES           S G S    G+  +S +G   S +G AS S  
Sbjct: 339 ESG--SGQTSGFGQHESGSGQ-------SSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQ 389

Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
              S+  + S    + A+  + G       S  QS G+     GS +   PS+       
Sbjct: 390 HGSSSRQSSSYGQHESASRHSSGRGQHSSGSG-QSPGHGQRGSGSGQ--SPSSGQHGTGF 446

Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
            R      + S        +G  H   + + +   + H S SGH +       +   + R
Sbjct: 447 GRSSSSGPYVSGSGY---SSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSR 503

Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTG 525
           G+R GSS  SS+ S  +  S + Q LG ++  S +G
Sbjct: 504 GERQGSSAGSSS-SYGQHGSGSRQSLGHSRHGSGSG 538



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 73/314 (23%), Positives = 113/314 (35%), Gaps = 41/314 (13%)

Query: 210  GDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGM 269
            G  S +G +   D S+  SS+Y   E   H + G     S S  +PG  + G        
Sbjct: 849  GQSSSSGQH---DSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRG-------- 897

Query: 270  AVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKS 329
              +G+   P      +G+  S ++G     + +S+G G  +++   +     G   S  S
Sbjct: 898  --SGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSG-SGHS 954

Query: 330  MAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAER 389
             +   + S  G S       S+S  G+S+S     S S+ S            S   +  
Sbjct: 955  SSYEQHGSRSGQSSRSEQHGSSS--GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1012

Query: 390  TEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKA 449
              G   G      QS  Y   R GS          W+ +        R P    S H  +
Sbjct: 1013 RHGSGSG------QSSSYGPYRSGSG---------WSSS--------RGPYESGSGH-SS 1048

Query: 450  GESHRRRAGDKNQKASSHRSASGHKNTRDDK-KEKGYSNVRGKRHGSSRKSSTHSSTKKE 508
            G  HR     ++     H S+SGH +T        G S+  G+   SS +SS+H      
Sbjct: 1049 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG 1108

Query: 509  SRTTQELGKNQSAS 522
            S  +   G+  S S
Sbjct: 1109 SSQSSGYGRQGSGS 1122



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 80/383 (20%), Positives = 133/383 (34%), Gaps = 18/383 (4%)

Query: 190  SGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYA--GGEGIQHASHGTASA 247
            S   P E   S  +   HRE    ++  Y     S+  SS +   G    Q +S G   A
Sbjct: 1505 SSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564

Query: 248  ASPSTSTPGAAEGGAARTAG-GMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGP 306
            +S  +S+ G    G+++++G G   +G+   P      +G+  SP+ G     + +S+  
Sbjct: 1565 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS 1624

Query: 307  GQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASL 366
            GQ  + L  ++     E+ S +S + + + S  G S       S S + +     G++S 
Sbjct: 1625 GQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSR 1684

Query: 367  S-----QDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP- 420
            S     Q  S S   +G       + +       G  +    S G      G      P 
Sbjct: 1685 SSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 1744

Query: 421  -SAEVWNENKERREKKDRHPSRKSSHHRKAGE-----SHRRRAGDKN---QKASSHRSAS 471
             S    +    + E    H S  S H   +G       H   +G  +   Q+ SS   +S
Sbjct: 1745 ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1804

Query: 472  GHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKA 531
             H        +      +G   G S     H S    S +  + G     SS+       
Sbjct: 1805 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1864

Query: 532  SKISSFLRSLRATPGSKTRVTSH 554
            S  SS      ++    +  T H
Sbjct: 1865 SGQSSGFGHHESSSWQSSGYTQH 1887



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 76/354 (21%), Positives = 127/354 (35%), Gaps = 27/354 (7%)

Query: 224 SAATSSAYA-----GGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGP 278
           SA +SS+Y        + + H+ HG+ S  SPS S      G    ++ G    G+    
Sbjct: 510 SAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSS 569

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMA----GAA 334
                 +G+  S   G     + +S+G GQ  ++   ++      + S +S +    GA 
Sbjct: 570 SRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGAT 629

Query: 335 NISSEGISLALVGAASTSLEGTSTSMAG--------AASLSQDSSLSAAFAGSITTSKCA 386
           +  S        G++ +S  G   S +G         +     SS     +GS  +S   
Sbjct: 630 SGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG 689

Query: 387 AERT---EGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKS 443
              +   +    G    + QS GY     GS   S          +  R ++    S  S
Sbjct: 690 PHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLS 749

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTR-DDKKEKGYSNVRGKRHGSSRKSSTH 502
           S + + G    + +G   Q      S SGH  +R       G+S+  G+    +  SS+ 
Sbjct: 750 SSYGQHGSGSHQSSGHGRQ-----GSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSC 804

Query: 503 SSTKKESRTTQELGKNQSASSTGALQK-KASKISSFLRSLRATPGSKTRVTSHD 555
              +  S      G+++S S  G  Q   AS   S      +T G  +    HD
Sbjct: 805 GHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHD 858



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 80/392 (20%), Positives = 143/392 (36%), Gaps = 55/392 (14%)

Query: 181  SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA 240
            S C      SG +         +++  R G Q       P      +   ++   G   +
Sbjct: 621  SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGS 680

Query: 241  SHGTASAASPSTSTPGAAEG-----GAARTAG------------GMAVAGTATG--PRTD 281
              G +S+  P  S  G + G     G+ +++G            G    G+ +G   R++
Sbjct: 681  GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740

Query: 282  VAIAGAAMSPATGAMSIATTKSAG-----------PGQVTTALAGAAIKNPGENESSKSM 330
               + + +S + G     + +S+G           P +V    +     + G++ S  S 
Sbjct: 741  QHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSC 800

Query: 331  AGAA---------------NISSEGISLALVGAAS--TSLEGTSTSMAGAASLSQDSSLS 373
            + +                + S  G   +  G+AS   S +G   S +G +S S     S
Sbjct: 801  SSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSS 860

Query: 374  AAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERRE 433
            +  + S    + A+    G       S  QS G+     GS +   PS         R  
Sbjct: 861  SGQSSSYGQHESASHHASGRGRHGSGSG-QSPGHGQRGSGSGQ--SPSYGRHGSGSGRSS 917

Query: 434  KKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRH 493
               RH S      + +G  H+  +G ++   + H S SGH ++ +    +   + R ++H
Sbjct: 918  SSGRHGSGSG---QSSGFGHKSSSG-QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973

Query: 494  GSSRKSSTHSSTKKESRTTQELGKNQSASSTG 525
            GSS  SS+ S  +  S + Q LG  Q  S +G
Sbjct: 974  GSSSGSSS-SYGQHGSGSRQSLGHGQHGSGSG 1004



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 18/366 (4%)

Query: 207  HREGDQSETGLYKPCDVSAATSSAYA--GGEGIQHASHGTASAASPSTSTPGAAEGGAAR 264
            HRE    ++  Y     S+  SS +   G    Q +S G   A+S  +S+ G    G+++
Sbjct: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2051

Query: 265  TAG-GMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGE 323
            ++G G   +G+   P      +G+  SP+ G     + +S+  GQ    L  ++     E
Sbjct: 2052 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHE 2111

Query: 324  NESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLS-----QDSSLSAAFAG 378
            + S +S + + + S  G S       S S + +     G++S S     Q  S S   +G
Sbjct: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171

Query: 379  SITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP--SAEVWNENKERREKKD 436
                   +         G       S G      G      P  S    +    + E   
Sbjct: 2172 HGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS 2231

Query: 437  RHPSRKSSHHRKAGE-----SHRRRAGDKN---QKASSHRSASGHKNTRDDKKEKGYSNV 488
             H S  S H   +G       H   +G  +   Q+ SS   +S H        +      
Sbjct: 2232 GHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ 2291

Query: 489  RGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSK 548
            +G   G S     H S    S +  + G     SS+       S  SS      ++    
Sbjct: 2292 QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 2351

Query: 549  TRVTSH 554
            +  T H
Sbjct: 2352 SGYTQH 2357



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 4/112 (3%)

Query: 413 GSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASG 472
           GS     P+         +    D H S      + +G S  + +  ++   S H S SG
Sbjct: 196 GSGSGQSPNYGQHGSGSGQSSSNDTHGSGSG---QSSGFSQHKSSSGQSSGYSQHGSGSG 252

Query: 473 HKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASST 524
           H +       +   + RG+RH SS  SS+ S  +  S + Q LG  +  S +
Sbjct: 253 HSSGYGQHGSRSGQSSRGERHRSSSGSSS-SYGQHGSGSRQSLGHGRQGSGS 303



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 60/312 (19%), Positives = 115/312 (36%), Gaps = 9/312 (2%)

Query: 229 SAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAG-GMAVAGTATGPRTDVAIAGA 287
           ++Y+G    Q +S+G  ++ S  +S  G    G+ ++   G   +G+      D   +G+
Sbjct: 170 NSYSG----QSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGS 225

Query: 288 AMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVG 347
             S        ++ +S+G  Q  +    ++      + S +S  G  + SS G S +   
Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285

Query: 348 AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTS--KCAAERTEGPAVGPLIS-TLQS 404
             S S +       G+ S    S +        ++S  +  +  +   + G   S + Q+
Sbjct: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345

Query: 405 EGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKA 464
            G+     GS + S  S           + +    S ++S   + G S R+ +    Q  
Sbjct: 346 SGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQ-SSSYGQHE 404

Query: 465 SSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASST 524
           S+ R +SG         +      RG   G S  S  H +    S ++         SS 
Sbjct: 405 SASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSG 464

Query: 525 GALQKKASKISS 536
               + +S+ SS
Sbjct: 465 FGHHESSSEHSS 476


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 26/206 (12%)

Query: 221  CDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRT 280
            C  +A T+S +A           T +A +  T  P  A    A T       GT  GP T
Sbjct: 1492 CSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLT 1551

Query: 281  DVAIAG-----------AAMSPATGAMSIATTKSAG----PGQVTTALAGAAIKNPGENE 325
            +    G           +  +  TG +S   T ++G     G V  A  GAA +N  E  
Sbjct: 1552 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA 1611

Query: 326  SSKSMAGAANISSEGISLALVGAASTSLE-GTSTSMAGAASLSQDSSLSAAFAGSITTSK 384
             +  ++GA            VG  ST  E G   +++G+  +S   S++A+   S T+S+
Sbjct: 1612 GTPRVSGAT---------PAVGGGSTPGEAGPGATVSGSTGVSA-GSITASPGASATSSE 1661

Query: 385  CAAERTEGPAVGPLISTLQSEGYMSE 410
             +   T GP+VG       SE   SE
Sbjct: 1662 SSKSGTTGPSVGGKTGATSSEATSSE 1687



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 49/195 (25%), Positives = 72/195 (36%), Gaps = 21/195 (10%)

Query: 210  GDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTAS------AASPSTS--TPGAAEGG 261
            G+   TG+  P    A+  +   GG  +  A+ G AS      A +P  S  TP    G 
Sbjct: 1570 GNAGMTGVVSPTVTGASGMAGTTGG--VDAATTGAASENTSERAGTPRVSGATPAVGGGS 1627

Query: 262  AARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNP 321
                AG  A    +TG    V+      SP   A S  ++KS   G       GA     
Sbjct: 1628 TPGEAGPGATVSGSTG----VSAGSITASPGASATSSESSKSGTTGPSVGGKTGATSSEA 1683

Query: 322  GENESSKSMAGAANISSEGISLALVGAASTSLEGTS----TSMAGAASLSQDSSLSAAFA 377
              +E    + G +  S+ G    +   A TS  G+S     +     S    S  +  + 
Sbjct: 1684 TSSEGMSGVTGQSLGSTAGSDSEI--TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEW- 1740

Query: 378  GSITTSKCAAERTEG 392
            G++ T+  A E T G
Sbjct: 1741 GNVATTGAAGENTSG 1755



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 60/250 (24%), Positives = 92/250 (36%), Gaps = 25/250 (10%)

Query: 178  PVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGI 237
            P  S  S+ +  SG   P       A        +  +G+      S A S +    +  
Sbjct: 1653 PGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTS 1712

Query: 238  QHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGA--AMSPATGA 295
               S        PS  +PG   GG     G +A  G A G  T  A+     ++   T A
Sbjct: 1713 FTGSSPPGKLTRPSPGSPGHFSGGTTEW-GNVATTGAA-GENTSGALGSTEGSVEATTSA 1770

Query: 296  MSIAT-----TKSAGPGQVTTALAGAAIKNPGENESS--KSMAGAANISSEGI------- 341
             S  T     T   GPG   TA++G  + +PG    +   S  G A+I +          
Sbjct: 1771 GSGNTAGTSGTGDTGPG--NTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSG 1828

Query: 342  --SLALVGAASTSLEGT-STSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAV--G 396
              SL ++  A      T S +   ++ +S+ +  ++A A +I+ SK     T G A   G
Sbjct: 1829 HDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGG 1888

Query: 397  PLISTLQSEG 406
             + S   S G
Sbjct: 1889 KITSGWSSSG 1898


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
            sapiens]
          Length = 2134

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 26/206 (12%)

Query: 221  CDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRT 280
            C  +A T+S +A           T +A +  T  P  A    A T       GT  GP T
Sbjct: 1676 CSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLT 1735

Query: 281  DVAIAG-----------AAMSPATGAMSIATTKSAG----PGQVTTALAGAAIKNPGENE 325
            +    G           +  +  TG +S   T ++G     G V  A  GAA +N  E  
Sbjct: 1736 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA 1795

Query: 326  SSKSMAGAANISSEGISLALVGAASTSLE-GTSTSMAGAASLSQDSSLSAAFAGSITTSK 384
             +  ++GA            VG  ST  E G   +++G+  +S   S++A+   S T+S+
Sbjct: 1796 GTPRVSGAT---------PAVGGGSTPGEAGPGATVSGSTGVSA-GSITASPGASATSSE 1845

Query: 385  CAAERTEGPAVGPLISTLQSEGYMSE 410
             +   T GP+VG       SE   SE
Sbjct: 1846 SSKSGTTGPSVGGKTGATSSEATSSE 1871



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 49/195 (25%), Positives = 72/195 (36%), Gaps = 21/195 (10%)

Query: 210  GDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTAS------AASPSTS--TPGAAEGG 261
            G+   TG+  P    A+  +   GG  +  A+ G AS      A +P  S  TP    G 
Sbjct: 1754 GNAGMTGVVSPTVTGASGMAGTTGG--VDAATTGAASENTSERAGTPRVSGATPAVGGGS 1811

Query: 262  AARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNP 321
                AG  A    +TG    V+      SP   A S  ++KS   G       GA     
Sbjct: 1812 TPGEAGPGATVSGSTG----VSAGSITASPGASATSSESSKSGTTGPSVGGKTGATSSEA 1867

Query: 322  GENESSKSMAGAANISSEGISLALVGAASTSLEGTS----TSMAGAASLSQDSSLSAAFA 377
              +E    + G +  S+ G    +   A TS  G+S     +     S    S  +  + 
Sbjct: 1868 TSSEGMSGVTGQSLGSTAGSDSEI--TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEW- 1924

Query: 378  GSITTSKCAAERTEG 392
            G++ T+  A E T G
Sbjct: 1925 GNVATTGAAGENTSG 1939



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 60/250 (24%), Positives = 92/250 (36%), Gaps = 25/250 (10%)

Query: 178  PVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGI 237
            P  S  S+ +  SG   P       A        +  +G+      S A S +    +  
Sbjct: 1837 PGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTS 1896

Query: 238  QHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGA--AMSPATGA 295
               S        PS  +PG   GG     G +A  G A G  T  A+     ++   T A
Sbjct: 1897 FTGSSPPGKLTRPSPGSPGHFSGGTTEW-GNVATTGAA-GENTSGALGSTEGSVEATTSA 1954

Query: 296  MSIAT-----TKSAGPGQVTTALAGAAIKNPGENESS--KSMAGAANISSEGI------- 341
             S  T     T   GPG   TA++G  + +PG    +   S  G A+I +          
Sbjct: 1955 GSGNTAGTSGTGDTGPG--NTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSG 2012

Query: 342  --SLALVGAASTSLEGT-STSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAV--G 396
              SL ++  A      T S +   ++ +S+ +  ++A A +I+ SK     T G A   G
Sbjct: 2013 HDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGG 2072

Query: 397  PLISTLQSEG 406
             + S   S G
Sbjct: 2073 KITSGWSSSG 2082


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
            sapiens]
          Length = 2134

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 57/206 (27%), Positives = 81/206 (39%), Gaps = 26/206 (12%)

Query: 221  CDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRT 280
            C  +A T+S +A           T +A +  T  P  A    A T       GT  GP T
Sbjct: 1676 CSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLT 1735

Query: 281  DVAIAGAAMSPA-----------TGAMSIATTKSAG----PGQVTTALAGAAIKNPGENE 325
            +    G   +             TG +S   T ++G     G V  A  GAA +N  E  
Sbjct: 1736 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSER- 1794

Query: 326  SSKSMAGAANISSEGISLALVGAASTSLE-GTSTSMAGAASLSQDSSLSAAFAGSITTSK 384
                 AG   +S E      VG  ST  E G   +++G+  +S   S++A+   S T+S+
Sbjct: 1795 -----AGTPRVSGE---TPAVGGGSTPGEAGPGATVSGSTGVSA-GSITASPGASATSSE 1845

Query: 385  CAAERTEGPAVGPLISTLQSEGYMSE 410
             +   T GP+VG       SE   SE
Sbjct: 1846 SSKSGTTGPSVGGKTGATSSEATSSE 1871



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 49/195 (25%), Positives = 72/195 (36%), Gaps = 21/195 (10%)

Query: 210  GDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTAS------AASPSTS--TPGAAEGG 261
            G+   TG+  P    A+  +   GG  +  A+ G AS      A +P  S  TP    G 
Sbjct: 1754 GNAGMTGVVSPTVTGASGMAGTTGG--VDAATTGAASENTSERAGTPRVSGETPAVGGGS 1811

Query: 262  AARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNP 321
                AG  A    +TG    V+      SP   A S  ++KS   G       GA     
Sbjct: 1812 TPGEAGPGATVSGSTG----VSAGSITASPGASATSSESSKSGTTGPSVGGKTGATSSEA 1867

Query: 322  GENESSKSMAGAANISSEGISLALVGAASTSLEGTS----TSMAGAASLSQDSSLSAAFA 377
              +E    + G +  S+ G    +   A TS  G+S     +     S    S  +  + 
Sbjct: 1868 TSSEGMSGVTGQSLGSTAGSDSEI--TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEW- 1924

Query: 378  GSITTSKCAAERTEG 392
            G++ T+  A E T G
Sbjct: 1925 GNVATTGAAGENTSG 1939



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 60/250 (24%), Positives = 92/250 (36%), Gaps = 25/250 (10%)

Query: 178  PVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGI 237
            P  S  S+ +  SG   P       A        +  +G+      S A S +    +  
Sbjct: 1837 PGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTS 1896

Query: 238  QHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGA--AMSPATGA 295
               S        PS  +PG   GG     G +A  G A G  T  A+     ++   T A
Sbjct: 1897 FTGSSPPGKLTRPSPGSPGHFSGGTTEW-GNVATTGAA-GENTSGALGSTEGSVEATTSA 1954

Query: 296  MSIAT-----TKSAGPGQVTTALAGAAIKNPGENESS--KSMAGAANISSEGI------- 341
             S  T     T   GPG   TA++G  + +PG    +   S  G A+I +          
Sbjct: 1955 GSGNTAGTSGTGDTGPG--NTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSG 2012

Query: 342  --SLALVGAASTSLEGT-STSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAV--G 396
              SL ++  A      T S +   ++ +S+ +  ++A A +I+ SK     T G A   G
Sbjct: 2013 HDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGG 2072

Query: 397  PLISTLQSEG 406
             + S   S G
Sbjct: 2073 KITSGWSSSG 2082


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 8/188 (4%)

Query: 224  SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283
            + ++ +  A   G +  +  T  + + + ST G+ E   +  AG  A   +  G  T  A
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGS-EATTSSAAGSEATTTSTEGSETTTA 1186

Query: 284  -IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKN----PGENESSKSMAGAANISS 338
              AG+  + A+ A S  TT S    + TTA    +  N     G   S+ S AG+   ++
Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246

Query: 339  EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGP--AVG 396
              I      A++ SLE T+TS+ G+ + +   + S A A S T S      T+    ++ 
Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 397  PLISTLQS 404
            P+ +T  S
Sbjct: 1307 PITNTPMS 1314



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E T  
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTAGSETTTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   +T  + G
Sbjct: 1217 STSGSETNTACTTG 1230



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 19/303 (6%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSS----RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKAS 532
                 E   ++  G    ++     ++ST SS   E+ T   +G   + +ST +L+  A+
Sbjct: 1209 AG--SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTAT 1266

Query: 533  KIS 535
             ++
Sbjct: 1267 SLT 1269



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/371 (18%), Positives = 137/371 (36%), Gaps = 29/371 (7%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST-----LQSEGYMSERDGSQKVSQPSAEV 424
            +++    + + TTS   +E T     G   +T     L++    +   G+   S   +E 
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 425  WNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKG 484
                              + +   +  +     G +    S+  S +   +T   +    
Sbjct: 1104 -----------------TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 485  YSNVRGKRHGSS--RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLR 542
            ++ V      S+   +++T S+   E+ TT   G   + +ST   +   +  +    +  
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 543  ATPGSKTRVTS 553
            +T GS+T   S
Sbjct: 1207 STAGSETTTAS 1217



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E    
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   ST  S G
Sbjct: 1217 CTTGSETSTPSSAG 1230



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
               +     +        +  ++ST SS   E+ T   +G   + +ST +L+  A+ ++
Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1259



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%)

Query: 224  SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276
            S  T+++ AG E       G +  +  T  + + + ST  +    A+ T   M    T  
Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150

Query: 277  GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332
               T V+  G+  + ++ A S ATT S    + TTA  AG+        G   ++ S +G
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 333  A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372
            +               ++  SE  +  ++G     A++ SLE T+TS+ G+ + +   + 
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 373  SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404
            S A A S T S      T+    ++ P+ +T  S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401
            +++    + + TTS   +E T     G   +T
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
               +     +        +  ++ST SS   E+ T   +G   + +ST +L+  A+ ++
Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLT 1259



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E    
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   ST  S G
Sbjct: 1217 CTTGSETSTPSSAG 1230



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 52/214 (24%), Positives = 90/214 (42%), Gaps = 33/214 (15%)

Query: 224  SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276
            S  T+++ AG E       G +  +  T  + + + ST  +    A+ T   M    T  
Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150

Query: 277  GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332
               T V+  G+  + ++ A S ATT S    + TTA  AG+        G   ++ S +G
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 333  A---------------ANISSEGISLALVGAAST-----SLEGTSTSMAGAASLSQDSSL 372
            +               ++  SE  +  ++G+ ST     SLE T+TS+ G+ + +   + 
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 373  SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404
            S A A S T S      T+    ++ P+ +T  S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401
            +++    + + TTS   +E T     G   +T
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 508 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 566

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 567 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 626

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 627 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 686

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 687 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 744

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 745 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 791

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 792 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 850

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 851 SETIPA----STAGSETTTTTSTEGSETT 875



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 443 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 502

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 503 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 557

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 558 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 617

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 618 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 672

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 673 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 720

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 721 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 776

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 777 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 822



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 88/386 (22%), Positives = 151/386 (39%), Gaps = 49/386 (12%)

Query: 197 DNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEG----IQHASHGTASAASPST 252
           D+K + A+ +      SET +  P   S  T+++  G E     I+ +   TAS A   T
Sbjct: 13  DSKVITASSM-----SSETTV-APAAGSNTTTASTTGSETTTILIKASETTTASTAGSET 66

Query: 253 STP---GAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAG---- 305
           +TP   G+     + +   +    TA    T V+ AG+  + A+ A S +T  +AG    
Sbjct: 67  TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETT 126

Query: 306 ----PGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGA-ASTSLEGTSTSM 360
                G  TT ++    +    + +S      +   SE  +++ VG+  +T+    S + 
Sbjct: 127 TVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT 186

Query: 361 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420
           A + + S+ +++  A + +IT S   +E T        +ST  SE       GS+  +  
Sbjct: 187 AASTTGSEMTTVFTAGSETITPSTAGSETT-------TVSTAGSETTTVSTTGSETTTAS 239

Query: 421 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480
           +A                 S  +       E+    AG +   AS+  S +    T D K
Sbjct: 240 TAH------SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 293

Query: 481 ----KEKGYSNVRGKRHGS--SRKSSTHSSTKKESRTTQELGKNQSASS-------TGAL 527
                  G+        GS  +  S+  S T   S    E  K  +ASS        G+ 
Sbjct: 294 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 353

Query: 528 QKKASKISSFLRSLRATPGSKTRVTS 553
             +AS + S   ++ +T GS+T   S
Sbjct: 354 TIRASTVGSETTTV-STTGSETTTAS 378



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1065 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1119

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1120 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1178

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E    
Sbjct: 1179 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1237

Query: 393  PAVGPLISTLQSEG 406
               G   ST  S G
Sbjct: 1238 CTTGSETSTPSSAG 1251



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 996  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1055

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1056 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1110

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1111 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1169

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1170 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1229

Query: 477  RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
               +     +        +  ++ST SS   E+ T   +G   + +ST +L+  A+ ++
Sbjct: 1230 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1280



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 777 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 836

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 837 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 896

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 897 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 955

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 956 TASTEGSELTTVSTTG 971



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%)

Query: 224  SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276
            S  T+++ AG E       G +  +  T  + + + ST  +    A+ T   M    T  
Sbjct: 1112 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1171

Query: 277  GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332
               T V+  G+  + ++ A S ATT S    + TTA  AG+        G   ++ S +G
Sbjct: 1172 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1231

Query: 333  A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372
            +               ++  SE  +  ++G     A++ SLE T+TS+ G+ + +   + 
Sbjct: 1232 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1291

Query: 373  SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404
            S A A S T S      T+    ++ P+ +T  S
Sbjct: 1292 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1325



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 887  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 946

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 947  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 1005

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 1006 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1064

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401
            +++    + + TTS   +E T     G   +T
Sbjct: 1065 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1096



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 243 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 302

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 303 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 352

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 353 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 412

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 413 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 470

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 471 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 522

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 523 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 578

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 579 TE-GSEMTTVSTTGAETTTDSTE 600



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 786  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 845

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 846  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 905

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 906  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 964

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 965  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 1017

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 1018 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1069

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1070 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1124


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E    
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   ST  S G
Sbjct: 1217 CTTGSETSTPSSAG 1230



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
               +     +        +  ++ST SS   E+ T   +G   + +ST +L+  A+ ++
Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1259



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%)

Query: 224  SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276
            S  T+++ AG E       G +  +  T  + + + ST  +    A+ T   M    T  
Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150

Query: 277  GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332
               T V+  G+  + ++ A S ATT S    + TTA  AG+        G   ++ S +G
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 333  A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372
            +               ++  SE  +  ++G     A++ SLE T+TS+ G+ + +   + 
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 373  SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404
            S A A S T S      T+    ++ P+ +T  S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401
            +++    + + TTS   +E T     G   +T
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E    
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   ST  S G
Sbjct: 1217 CTTGSETSTPSSAG 1230



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
               +     +        +  ++ST SS   E+ T   +G   + +ST +L+  A+ ++
Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1259



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%)

Query: 224  SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276
            S  T+++ AG E       G +  +  T  + + + ST  +    A+ T   M    T  
Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150

Query: 277  GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332
               T V+  G+  + ++ A S ATT S    + TTA  AG+        G   ++ S +G
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 333  A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372
            +               ++  SE  +  ++G     A++ SLE T+TS+ G+ + +   + 
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 373  SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404
            S A A S T S      T+    ++ P+ +T  S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401
            +++    + + TTS   +E T     G   +T
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 8/188 (4%)

Query: 224  SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283
            + ++ +  A   G +  +  T  + + + ST G+ E   +  AG  A   +  G  T  A
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGS-EATTSSAAGSEATTTSTEGSETTTA 1186

Query: 284  -IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKN----PGENESSKSMAGAANISS 338
              AG+  + A+ A S  TT S    + TTA    +  N     G   S+ S AG+   ++
Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246

Query: 339  EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGP--AVG 396
              I      A++ SLE T+TS+ G+ + +   + S A A S T S      T+    ++ 
Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 397  PLISTLQS 404
            P+ +T  S
Sbjct: 1307 PITNTPMS 1314



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E T  
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTAGSETTTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   +T  + G
Sbjct: 1217 STSGSETNTACTTG 1230



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 19/303 (6%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSS----RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKAS 532
                 E   ++  G    ++     ++ST SS   E+ T   +G   + +ST +L+  A+
Sbjct: 1209 AG--SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTAT 1266

Query: 533  KIS 535
             ++
Sbjct: 1267 SLT 1269



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/371 (18%), Positives = 137/371 (36%), Gaps = 29/371 (7%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST-----LQSEGYMSERDGSQKVSQPSAEV 424
            +++    + + TTS   +E T     G   +T     L++    +   G+   S   +E 
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 425  WNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKG 484
                              + +   +  +     G +    S+  S +   +T   +    
Sbjct: 1104 -----------------TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 485  YSNVRGKRHGSS--RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLR 542
            ++ V      S+   +++T S+   E+ TT   G   + +ST   +   +  +    +  
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 543  ATPGSKTRVTS 553
            +T GS+T   S
Sbjct: 1207 STAGSETTTAS 1217



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 8/188 (4%)

Query: 224  SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283
            + ++ +  A   G +  +  T  + + + ST G+ E   +  AG  A   +  G  T  A
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGS-EATTSSAAGSEATTTSTEGSETTTA 1186

Query: 284  -IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKN----PGENESSKSMAGAANISS 338
              AG+  + A+ A S  TT S    + TTA    +  N     G   S+ S AG+   ++
Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246

Query: 339  EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGP--AVG 396
              I      A++ SLE T+TS+ G+ + +   + S A A S T S      T+    ++ 
Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 397  PLISTLQS 404
            P+ +T  S
Sbjct: 1307 PITNTPMS 1314



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E T  
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTAGSETTTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   +T  + G
Sbjct: 1217 STSGSETNTACTTG 1230



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 19/303 (6%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSS----RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKAS 532
                 E   ++  G    ++     ++ST SS   E+ T   +G   + +ST +L+  A+
Sbjct: 1209 AG--SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTAT 1266

Query: 533  KIS 535
             ++
Sbjct: 1267 SLT 1269



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/371 (18%), Positives = 137/371 (36%), Gaps = 29/371 (7%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST-----LQSEGYMSERDGSQKVSQPSAEV 424
            +++    + + TTS   +E T     G   +T     L++    +   G+   S   +E 
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 425  WNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKG 484
                              + +   +  +     G +    S+  S +   +T   +    
Sbjct: 1104 -----------------TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146

Query: 485  YSNVRGKRHGSS--RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLR 542
            ++ V      S+   +++T S+   E+ TT   G   + +ST   +   +  +    +  
Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 543  ATPGSKTRVTS 553
            +T GS+T   S
Sbjct: 1207 STAGSETTTAS 1217



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
               +     +        +  ++ST SS   E+ T   +G   + +ST +L+  A+ ++
Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLT 1259



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E    
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   ST  S G
Sbjct: 1217 CTTGSETSTPSSAG 1230



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 52/214 (24%), Positives = 90/214 (42%), Gaps = 33/214 (15%)

Query: 224  SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276
            S  T+++ AG E       G +  +  T  + + + ST  +    A+ T   M    T  
Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150

Query: 277  GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332
               T V+  G+  + ++ A S ATT S    + TTA  AG+        G   ++ S +G
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 333  A---------------ANISSEGISLALVGAAST-----SLEGTSTSMAGAASLSQDSSL 372
            +               ++  SE  +  ++G+ ST     SLE T+TS+ G+ + +   + 
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 373  SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404
            S A A S T S      T+    ++ P+ +T  S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401
            +++    + + TTS   +E T     G   +T
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 13/169 (7%)

Query: 429 KERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNV 488
           ++R ++K+R  SR  SH R      R R+  + +K S  RS    K +R   +E+  S  
Sbjct: 50  EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE-RKKSRSRSRERKKSRS 108

Query: 489 RGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGS- 547
           R +      +S + S ++   RT     ++++ S +   +K+  K   F RSL  TP   
Sbjct: 109 RSRERKRRIRSRSRSRSRHRHRTR---SRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165

Query: 548 --KTRVTSHDREVDIV-----AKMVEKQNIEAKVEKAQGGQELEMISGT 589
             + R T+ D +  +      AK +++Q  +  VEK Q  QE+   + T
Sbjct: 166 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEK-QKQQEIAAAAAT 213



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%)

Query: 437 RHPSRKSSHHRKAGESHRRRAGDKNQKASSHRS-ASGHKNTRDDKKEKGYSNVRGKRHGS 495
           RH S+  S  +   E H     DK   +   R   +  +N  D  K K   + RG+ H  
Sbjct: 13  RHESKDKSSKKHKSEEH----NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68

Query: 496 SR-KSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTR 550
           SR +   H S  +E + ++   + +  S + + ++K S+  S  R  R    S++R
Sbjct: 69  SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 124



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 10/142 (7%)

Query: 427 ENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYS 486
           +   ++ K + H  ++ S  +     +    G+   K    +S+ G  ++R   +E+ + 
Sbjct: 18  DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 77

Query: 487 NVRGKRHGSSRKSSTHSSTKKESRT-TQELGKNQSASSTGALQKKASKISSFLRSLRATP 545
           +    R    +KS + S  +K+SR+ ++E  K++S S     + ++   S      R   
Sbjct: 78  S----RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 133

Query: 546 GSKTRVTSHDREVDIVAKMVEK 567
            S+TR  S DR+     K +EK
Sbjct: 134 RSRTRSRSRDRK-----KRIEK 150



 Score = 33.1 bits (74), Expect = 0.76
 Identities = 38/176 (21%), Positives = 64/176 (36%), Gaps = 29/176 (16%)

Query: 426 NENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGY 485
           + ++ R  KK R  SR+    R      +RR   +++  S HR       TR   + +  
Sbjct: 86  SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR-----HRTRSRSRTRSR 140

Query: 486 SNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATP 545
           S  R KR    R+ S   S  +        G+N +  +  AL ++               
Sbjct: 141 SRDRKKRIEKPRRFS--RSLSRTPSPPPFRGRNTAMDAQEALARRL-------------- 184

Query: 546 GSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELE----MISGTMTSEKTEM 597
             + +     RE ++V K  ++   E     A GG  L     + SGT  + +  M
Sbjct: 185 -ERAKKLQEQREKEMVEKQKQQ---EIAAAAATGGSVLNVAALLASGTQVTPQIAM 236


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 13/169 (7%)

Query: 429 KERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNV 488
           ++R ++K+R  SR  SH R      R R+  + +K S  RS    K +R   +E+  S  
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE-RKKSRSRSRERKKSRS 167

Query: 489 RGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGS- 547
           R +      +S + S ++   RT     ++++ S +   +K+  K   F RSL  TP   
Sbjct: 168 RSRERKRRIRSRSRSRSRHRHRTR---SRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224

Query: 548 --KTRVTSHDREVDIV-----AKMVEKQNIEAKVEKAQGGQELEMISGT 589
             + R T+ D +  +      AK +++Q  +  VEK Q  QE+   + T
Sbjct: 225 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEK-QKQQEIAAAAAT 272



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 8/148 (5%)

Query: 407 YMSERDGSQKVSQPSAEVWNENKERREKKD--RHPSRKSSHHRKAGESHRRRAGDKNQKA 464
           Y   R  S++  + S     +++ R   K+  RH S+  S  +   E H     DK   +
Sbjct: 40  YSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEH----NDKEHSS 95

Query: 465 SSHRS-ASGHKNTRDDKKEKGYSNVRGKRHGSSR-KSSTHSSTKKESRTTQELGKNQSAS 522
              R   +  +N  D  K K   + RG+ H  SR +   H S  +E + ++   + +  S
Sbjct: 96  DKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKS 155

Query: 523 STGALQKKASKISSFLRSLRATPGSKTR 550
            + + ++K S+  S  R  R    S++R
Sbjct: 156 RSRSRERKKSRSRSRERKRRIRSRSRSR 183



 Score = 33.1 bits (74), Expect = 0.76
 Identities = 38/176 (21%), Positives = 64/176 (36%), Gaps = 29/176 (16%)

Query: 426 NENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGY 485
           + ++ R  KK R  SR+    R      +RR   +++  S HR       TR   + +  
Sbjct: 145 SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR-----HRTRSRSRTRSR 199

Query: 486 SNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATP 545
           S  R KR    R+ S   S  +        G+N +  +  AL ++               
Sbjct: 200 SRDRKKRIEKPRRFS--RSLSRTPSPPPFRGRNTAMDAQEALARRL-------------- 243

Query: 546 GSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELE----MISGTMTSEKTEM 597
             + +     RE ++V K  ++   E     A GG  L     + SGT  + +  M
Sbjct: 244 -ERAKKLQEQREKEMVEKQKQQ---EIAAAAATGGSVLNVAALLASGTQVTPQIAM 295


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
           sapiens]
          Length = 1521

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TGL      +  + +  A  EG +  +     +   + ST G+ E     T G     
Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            + TG  T       +           TT  +  G  TTA + A  +    + +      
Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387
           A+   SE  S +  G     A++TS E T+ S  G+ + +  ++ S     S T S+   
Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
             TEG     + +T       +E  G+  VS   +E    +    E      S + S   
Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSE--TTITSTEGSEIT 723

Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507
            A  +     G +   AS+  S +   +T      +G         GS  +++T S+T  
Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770

Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566
           E+     +G   + +ST G+   K S  SS + ++  T  S+T + S             
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829

Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595
            + I A    +  G E    + T  SE T
Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%)

Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278
           +++A +++ +         S  T ++ S S +T  + EG       TAG        TG 
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A      +     +   TT ++  G  TTA++       G   ++ S  G+ N + 
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536

Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384
                     ++T LE T+TS  G+         A  + DS     + +A+ AGS TT+ 
Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596

Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442
             A+     A     ST  SE   +   GS+    S  S+E    + E  E      +  
Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +       S R     +  + ++  SA+G + T           V  +  G++  S T 
Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699

Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
           S T K S T    G   + +ST   +   + I+    +  +T GS+T   S +      A
Sbjct: 700 SETTKVSTT----GSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755

Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603
                +   A    ++       G E  M S T+ SE T++    +K
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%)

Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281
           +S+ T+ A A G     AS    + +  +T    A+E   A TAG      + TG +T  
Sbjct: 1   MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57

Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336
           V+I+G+ ++  + A S  TT  SAG G  T ++AG+   +   G   ++ S+ G     +
Sbjct: 58  VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117

Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
           S+ G         S     TS  G+ T   S  G+ + +  ++ S   A S T S+    
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443
            T G   + P  ST  SE       GS+   VS   +E    +    E        S  +
Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235

Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497
                  E+    AG +   AS+  S +    T D K       G+        GS  + 
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295

Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550
            S+  S T   S    E  K  +ASS        G+   +AS + S   ++ +T GS+T 
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354

Query: 551 VTS 553
             S
Sbjct: 355 TAS 357



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%)

Query: 215  TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274
            T +Y     +  TS+     EG +  +  T  + + + ST        + +  G   A T
Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 275  ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
            A    T V I G+  + A+   S ATT S    + TTA    +         S++    +
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157

Query: 335  NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392
             I SE  + +  G  A +TS EG+ T+ A  A  S+ ++ S A + + T S   +E    
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216

Query: 393  PAVGPLISTLQSEG 406
               G   ST  S G
Sbjct: 1217 CTTGSETSTPSSAG 1230



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%)

Query: 244  TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301
            TAS A   T+T   A  E   A   G      ++TG  T         +  T      TT
Sbjct: 975  TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034

Query: 302  KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361
                 G  TTA     +   G   ++ S  G+   +          A++  LE T+ S +
Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089

Query: 362  GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418
            G+ + +  ++ S      IT SK     TEG +    +ST  SE   +   GS+  +   
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148

Query: 419  --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476
                +  V     E            ++    +  +    AG +   AS+  S +   +T
Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208

Query: 477  RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
               +     +        +  ++ST SS   E+ T   +G   + +ST +L+  A+ ++
Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1259



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%)

Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272
           S TG       + ++ +  A   G +     T  + +   ST  +             +A
Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332
            T     T V+ AG+   PA+ A S  TT ++  G  TT  +    +    +  S     
Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875

Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390
           A  I SE  + +  G+   +TS EG+ T+ A     S+ +++S   + + T S   +E T
Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934

Query: 391 EGPAVGPLISTLQSEG 406
                G  ++T+ + G
Sbjct: 935 TASTEGSELTTVSTTG 950



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%)

Query: 224  SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276
            S  T+++ AG E       G +  +  T  + + + ST  +    A+ T   M    T  
Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150

Query: 277  GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332
               T V+  G+  + ++ A S ATT S    + TTA  AG+        G   ++ S +G
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 333  A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372
            +               ++  SE  +  ++G     A++ SLE T+TS+ G+ + +   + 
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 373  SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404
            S A A S T S      T+    ++ P+ +T  S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%)

Query: 193  APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251
            A  E +++  A  +  E   + T G       +  + +  A  EG +  +  T  + + +
Sbjct: 866  ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925

Query: 252  TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             ST G+ E   A T G      + TG  T    A  + +     M   TT ++  G  TT
Sbjct: 926  ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
             ++ A  +    +         ++  SE  +++  G  +T  S EG+ T+    A  S+ 
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401
            +++    + + TTS   +E T     G   +T
Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%)

Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278
           S  T+++  G E  + ++ G+ +  S + S   AA     E   A T        + TG 
Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281

Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338
            T  A    +       M   TT ++  G  TT ++ A          S  +       S
Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331

Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397
           E I  + VG+ +T++  T +    A+ +  ++S  +      TT+    +E T     G 
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391

Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457
             +T+ + G  SE          +     E  E            ++    +  +    +
Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449

Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517
             +   AS+  S +    T   + +  Y+        +  +++T S+T  E+ T   +G 
Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501

Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576
           + + +ST   +  A   +    +  +T GS+ T V++   E   V+       +E     
Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557

Query: 577 AQGGQELEMISGT---MTSEKTE 596
            + G E+  +S T    T++ TE
Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%)

Query: 193  APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252
            A    +++ +A+ +  E   + T   +   VS A+S            +  + +A+  +T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824

Query: 253  STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311
             +   +E   A TAG      T+T G  T  A    + +      S  TT +   G  TT
Sbjct: 825  VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884

Query: 312  ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369
              +    +    +        A+   SE  +++  G+ +T  S EG+ T+ A     S+ 
Sbjct: 885  TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943

Query: 370  SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429
            +++S   + +IT S   +E T        ++T+ SE   +   GS+  +  +A       
Sbjct: 944  TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996

Query: 430  ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489
                 +    S   S       +     G +    S+  S +    T   +    Y+   
Sbjct: 997  SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048

Query: 490  GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549
                 +  +++T S+   E+ T    G   + +ST  L+      S    +  +T GS+T
Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 42/175 (24%), Positives = 81/175 (46%), Gaps = 2/175 (1%)

Query: 214  ETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAG 273
            ++G  K  D + A        E    +S G++S++S S+S+    EG       G    G
Sbjct: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG--G 2594

Query: 274  TATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGA 333
              TG R   A +  A SPA+ + S +++ S+     +++ + ++  +   + SS S + +
Sbjct: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2654

Query: 334  ANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAE 388
            ++ SS   S +   ++ST+ E +S S    A+ +  +  SA  A     +K A +
Sbjct: 2655 SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGK 2709



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 63/304 (20%), Positives = 113/304 (37%), Gaps = 39/304 (12%)

Query: 245  ASAASPSTSTPGAAEGGAARTAG-GMAVAGTATGPRTDVAIA---GAAMSPATGAMSIAT 300
            A ++ P    P A +G  A+  G G+    +      D A A   GA  S ++      +
Sbjct: 2508 AGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESS------S 2561

Query: 301  TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM 360
            + S+G    +++ + +  +  GE E  K+  G         S A   AAS +   +S+S 
Sbjct: 2562 SSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSS 2621

Query: 361  AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420
            + ++S S  SS S++ + S ++S  +             S+  S    S    S   S  
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSS-------------SSSSSSSSSSSSSSSSSSSSS 2668

Query: 421  SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480
            S+   +E+       +  P+        AG S +     K  K +     S H   +   
Sbjct: 2669 SSSTTDEDSSCSSDDEAAPA------PTAGPSAQAALPTKATKQAGKARPSAHSPGKKTP 2722

Query: 481  KEKGYSNVRGKRHGSSRKSSTHSSTKKESR------TTQELGKNQSASSTGALQKKASKI 534
              +  +           K+   + ++ + R      TT+EL K Q   S     +   KI
Sbjct: 2723 APQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSV----ENRPKI 2778

Query: 535  SSFL 538
            ++FL
Sbjct: 2779 AAFL 2782


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 74/332 (22%), Positives = 123/332 (37%), Gaps = 25/332 (7%)

Query: 211  DQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMA 270
            D    G  +  +  + ++S    G   + + HG+    S      G      +    G  
Sbjct: 949  DSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTP 1008

Query: 271  VAGTATGPRTDVAIAGAAMSPAT--GAMSIATTKSAGPGQVTTALAGAAIKNPGENESSK 328
             A T++G +   +   A  SP    G+    +  S+    +    A +A+++ G   SS 
Sbjct: 1009 HAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSG 1068

Query: 329  SMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQD-SSLSAAFAGSITTSKCAA 387
            S A  +   SE      V           +    A   S   S  S +F   ++T     
Sbjct: 1069 SQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTH---- 1124

Query: 388  ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447
            E++E        ST + +G  S  + ++  S+ SA    ++  R     R   R+ SHH 
Sbjct: 1125 EQSESAHGRTRTSTGRRQG--SHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHE 1182

Query: 448  KAGE------SHRRRAGDKNQKASSHR---SASGHKNTRDDKKEKGYSNVRGKRH---GS 495
            ++ +      SH      + +  +SH    S S  + TR DK+    S   G RH    S
Sbjct: 1183 QSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAAS 1242

Query: 496  SRKSSTHSSTKKE----SRTTQELGKNQSASS 523
               SS HS   +E    SRT++  G + S  S
Sbjct: 1243 WADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS 1274



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 14/287 (4%)

Query: 240 ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299
           ASHG ++ +S  + T  A      +TA     A ++ G R       +A S    A    
Sbjct: 344 ASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSA---- 399

Query: 300 TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359
                G GQ ++A++    +    +++S S   + N  ++ +S    G A    +    S
Sbjct: 400 ----TGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGH--GKAGLRQQSHQES 453

Query: 360 MAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQ 419
             G +      S S+ +  S      +A    G + G    +   +   S R  + +  Q
Sbjct: 454 TRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQ 513

Query: 420 PSAEVW-NENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRD 478
            +       ++  R+      S   S H  +  SH    G  +       S S  + TR+
Sbjct: 514 DTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRN 573

Query: 479 DKKEKGYSNVRGKRH---GSSRKSSTHSSTKKESRTTQELGKNQSAS 522
           +++    +   G RH    S   SS HS   +   +     +NQ +S
Sbjct: 574 EEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSS 620



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 64/297 (21%), Positives = 108/297 (36%), Gaps = 27/297 (9%)

Query: 240 ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299
           A HG ++ +S  + T       + + A     A ++ G R                 S  
Sbjct: 668 AGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERH---------GSRHQLQSAD 718

Query: 300 TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359
           +++ +G G      A +A+++ G   SS S A  +   SE      V     +     + 
Sbjct: 719 SSRHSGTGH---GQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSH 775

Query: 360 MAGAASLSQDSSL-SAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQ-KV 417
              A   S + S  S +F   ++T K  +E + G   GP     Q   +   RD S+   
Sbjct: 776 QESARDRSGERSRRSGSFLYQVSTHK-QSESSHG-WTGPSTGVRQGSHHEQARDNSRHSA 833

Query: 418 SQPSAEV--WNENKERREKKDRHPSRK--SSHHRKAGESHRRRAGDKNQKASSHRSASGH 473
           SQ   +    +    RR ++  H  +    S H  +  SH    G  +       S S  
Sbjct: 834 SQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 893

Query: 474 KNTRDDKKEKGYSNVRGKRHGS-------SRKSSTHSSTKKESRTTQELGKNQSASS 523
           + TR++++ +  S   G RH         SR S       + SRT++  G + S  S
Sbjct: 894 RTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDS 950



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 33/161 (20%)

Query: 403  QSEGYMSERDGSQKVSQPS--------AEVWNENKERR-----EKKDRHPSR--KSSHHR 447
            QSEG    R     VSQ S        +E W+ +  R      +++ RH SR  +S H  
Sbjct: 3201 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHED 3260

Query: 448  KAGESH----RRRAGDKNQKASS-HRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +AG  H     R++G ++ + SS  ++AS H+  R    E+      G RH  S  SS H
Sbjct: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGER-----HGSRHQQSADSSRH 3315

Query: 503  --------SSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
                    SS  ++SR     G   S S   + +     +S
Sbjct: 3316 SGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVS 3356



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 25/130 (19%)

Query: 403  QSEGYMSERDGSQKVSQPS--------AEVWNENKERR-----EKKDRHPSR--KSSHHR 447
            QSEG  + R     VSQ S        +E W+ +  R      +++ RH SR  +S H  
Sbjct: 932  QSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHED 991

Query: 448  KAGESH----RRRAGDKNQKASS-HRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502
            +AG  H     R++G  + + SS  ++AS H+  R    E+      G RH  S  SS H
Sbjct: 992  RAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGER-----HGSRHQQSADSSRH 1046

Query: 503  SSTKKESRTT 512
            S   +   ++
Sbjct: 1047 SGIPRRQASS 1056



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 52/190 (27%), Positives = 83/190 (43%), Gaps = 21/190 (11%)

Query: 347  GAASTSLEGTSTSMAGAASLSQDSSL--SAAFAGSITTSKCAAERTEGPAVGPLISTLQS 404
            G+ S S +      +G  S    S    +A++A S   S+   E++ G        +  S
Sbjct: 1212 GSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271

Query: 405  EGYMSER--DGSQKVSQPSAEVWNENKERREKKD--RHPS----RKSSHHRKAGESHRRR 456
            +   SER  D S+++S  SA   +    R + +D  RHP      ++SH   A  S  R+
Sbjct: 1272 QDSDSERHSDDSERLSG-SASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSS--RQ 1328

Query: 457  AGDKNQKASSHRSA-SGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSST--KKESRTTQ 513
            +G  + ++SSH  A S H+  R    E+      G RH  S  SS HS    ++ S   +
Sbjct: 1329 SGTHHTESSSHGQAVSSHEQARSSPGER-----HGSRHQQSADSSRHSGIGHRQASSAVR 1383

Query: 514  ELGKNQSASS 523
            + G   S+ S
Sbjct: 1384 DSGHRGSSGS 1393



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 89/415 (21%), Positives = 143/415 (34%), Gaps = 65/415 (15%)

Query: 225 AATSSAYAGGEGIQHASHG-TASAASPSTSTPGAAEGG--------AARTAGGMAVAGTA 275
           +A SS  +G    + +S G TAS+   + S+PG   G         +  +A G   A +A
Sbjct: 349 SADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSA 408

Query: 276 TGPRTDVAIAGAAMSPATGAMSIATTKS-AGPGQVTTALAGAAIKNPGENESSKSMAGAA 334
              R     +G+  S + G    + T+S +G G+       A ++     ES++  +G  
Sbjct: 409 VSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGK-------AGLRQQSHQESTRGRSGER 461

Query: 335 NISSEGISLALVGA-----ASTSLEGTSTSMAGAASLSQ--DSSLSAAFAGSITTSKCAA 387
           +  S G SL  V       ++    GTST     +   Q  DSS  +A      T +   
Sbjct: 462 SGRS-GSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHP 520

Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP------------SAEVWNENKERREKK 435
             + G   G       +    S    S   SQ             SA     N+E+    
Sbjct: 521 GSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDG 580

Query: 436 DRHPSRK---------SSHHRKAGE---SHRRRAGDKNQKASSHRSASGHKNTRDDKKEK 483
            RH   +         SS H + G+   S  R + ++    S    + GH    +     
Sbjct: 581 TRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGS 640

Query: 484 GYSNVRGKRHGSSRKSSTH----------------SSTKKESRTTQELGKNQSASSTGAL 527
              N  G     SR  S H                SS K  +R TQ     Q+ASS    
Sbjct: 641 ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQA 700

Query: 528 QKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQE 582
           +  A +       L++   S+   T H +    V     + +  ++   ++G  E
Sbjct: 701 RSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSE 755



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 69/314 (21%), Positives = 114/314 (36%), Gaps = 23/314 (7%)

Query: 230  AYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGM---AVAGTATGPRTDVAIAG 286
            ++   +G   AS G + + S S  T    + G      G      +  A   R  +   G
Sbjct: 2169 SHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQG 2228

Query: 287  AAMSPAT----GAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGIS 342
             +  P T    G+     + S G  + +   +G+A +N   +   +S  G+ +  S    
Sbjct: 2229 QSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED 2288

Query: 343  LALVGAASTSLEGTST-----SMAGAASLSQDSSLSAAFA--GSITTSKCAAERTEGPAV 395
             A  G ++ S   + T     S  G A+ S + + S+A    GS       + R  G   
Sbjct: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2348

Query: 396  GPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHR- 454
            G   S ++  G+     GS       +E  +E+ + +        +   H +   ES R 
Sbjct: 2349 GQASSAVRDSGHR----GSSGSQASDSEGHSEDSDTQSVSAH--GQAGPHQQSHQESTRG 2402

Query: 455  RRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQE 514
            R AG   +  S     S H+ +       G S   G R GS  K +  SS    S+  Q+
Sbjct: 2403 RSAGRSGRSGSFLYQVSTHEQSESAHGRTGTST--GGRQGSHHKQARDSSRHSTSQEGQD 2460

Query: 515  LGKNQSASSTGALQ 528
                   SS+G  Q
Sbjct: 2461 TIHGHPGSSSGGRQ 2474



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 81/365 (22%), Positives = 132/365 (36%), Gaps = 47/365 (12%)

Query: 225  AATSSAYAGGEGIQHASHGTA-SAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283
            +A SS  +G    + +SHG A S+   + S+PG   G   + +   A +   +G     A
Sbjct: 1322 SADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQS---ADSSRHSGIGHRQA 1378

Query: 284  IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESS-KSMAGAANISSEGIS 342
             +    S   G+     T S G  + +   + +A    G ++ S K  A   +  S G S
Sbjct: 1379 SSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRS 1438

Query: 343  LALVGAASTSLEGTSTSMAGAASL----------SQDSSLSAAFAGSITTSKCAAERTEG 392
             + +   S+  +  ST    A S           +++SS  +A      T +     + G
Sbjct: 1439 RSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRG 1498

Query: 393  PAVGPL----ISTLQSEGY-------MSERDGSQKVSQP-SAEVWNENKERREKKDRHPS 440
               G      +      GY           D S   S P SA     N+E+     RH  
Sbjct: 1499 GRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSG 1558

Query: 441  RKSSHHR---KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKR----- 492
              S HH    +AG S   + G + + A S  S     +   D+  +G+S    +R     
Sbjct: 1559 --SRHHEPSTRAGSSRHSQVG-QGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615

Query: 493  ---HGSSRKSSTHSSTKKESRTTQELGKNQSASST------GALQKKASKISSFLRSLRA 543
               +GS+R+ S H S    S          SA S+       A      + +S     R+
Sbjct: 1616 RNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARS 1675

Query: 544  TPGSK 548
            +PG +
Sbjct: 1676 SPGER 1680



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 17/162 (10%)

Query: 409  SERDGSQKVSQPSAEVWNENKERREK------------KDRHPSRKSSHHRKAGESHRRR 456
            S R GS       +E  +E+ ERR +            + RH SR    H++   SH   
Sbjct: 1587 SRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHS 1646

Query: 457  AGDKNQKASSHR--SASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSST--KKESRTT 512
            A    Q  + H   S+ G   +  ++         G RH  S  SST S T  +++S   
Sbjct: 1647 AESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVV 1706

Query: 513  QELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSH 554
             + G N+ +S + A   +     S  +S+ A   +     SH
Sbjct: 1707 GDSG-NRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSH 1747



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 12/169 (7%)

Query: 398  LISTLQSEGYMSERDGSQKVSQPS-AEVWNENKERREKKDRHPSRKSSHHRKAGESHRRR 456
            L+   QS G  + R     VSQ S +E  +E+ ERR       S   +HH  A E  + R
Sbjct: 2224 LVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSG-----SASRNHHGSAQE--QSR 2276

Query: 457  AGDKNQKASSHRSASGHKNTRDDKKEKG---YSNVRGKRHGSSRKSSTHSSTKKESRTTQ 513
             G ++ + S H   +GH ++ +  ++ G     N  G +  SS + +  S+ ++     Q
Sbjct: 2277 DGSRHPR-SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQ 2335

Query: 514  ELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
            +   +   S  G  Q  ++   S  R    +  S +   S D +   V+
Sbjct: 2336 QSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS 2384



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 55/279 (19%), Positives = 107/279 (38%), Gaps = 22/279 (7%)

Query: 240  ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299
            A HG ++ +S  + T         + A     A ++ G R       +A S     +   
Sbjct: 2614 AGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI--- 2670

Query: 300  TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359
                 G GQ ++A+  +  +    +++S +   + +  ++ +S    G A +  +    S
Sbjct: 2671 -----GHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH--GQAGSHQQSHQES 2723

Query: 360  MAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQ-KVS 418
              G +   + S  S +F   ++T +  +E + G   GP     Q   +   +D S+   S
Sbjct: 2724 ARGRSG--ETSGHSGSFLYQVSTHE-QSESSHG-WTGPSTRGRQGSRHEQAQDSSRHSAS 2779

Query: 419  QPSAEVWN----ENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHK 474
            Q   +        ++  R+      S  SS H  +  SH    G  +       S S  +
Sbjct: 2780 QDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 2839

Query: 475  NTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQ 513
             TR++++    S   G RH    ++STH+   + S+  Q
Sbjct: 2840 TTRNEEQSGDGSRHSGSRH---HEASTHADISRHSQAVQ 2875



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 23/127 (18%)

Query: 391  EGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKD---------RHPSR 441
            +G + GP   T +++G    +D   +     +E W+ +  R  +           RHP+ 
Sbjct: 3523 QGQSAGP--RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPT- 3579

Query: 442  KSSHHRKAGESH----RRRAGDKN-QKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSS 496
             S H  +AG  H     R++G  + + +S  ++AS H+  R    E+      G  H  S
Sbjct: 3580 -SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER-----HGSHHQQS 3633

Query: 497  RKSSTHS 503
              SS HS
Sbjct: 3634 ADSSRHS 3640



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 25/114 (21%)

Query: 438 HPSRKSSHH--------------RKAGESHRRRAGDKNQK--ASSHRSASG--HKNTRDD 479
           H  RK SHH              RK   S  RR   K  K  + S R   G  H+++ + 
Sbjct: 99  HKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEK 158

Query: 480 KKEKGYSNV-RGKRHGSSRKSSTHSSTKKESRTTQ--ELGKNQSASSTGALQKK 530
           K+ KGYS   R + +G +     H+S+KKE   T+   LG N+   S    +K+
Sbjct: 159 KERKGYSPTHREEEYGKNH----HNSSKKEKNKTENTRLGDNRKRLSERLEEKE 208



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 65/300 (21%), Positives = 102/300 (34%), Gaps = 34/300 (11%)

Query: 240  ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299
            A HG ++ +S  + T  A      + A     A ++ G R       +A S     +   
Sbjct: 2290 AGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI--- 2346

Query: 300  TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGI---SLALVGAASTSLEGT 356
                 G GQ     A +A+++ G   SS S A  +   SE     S++  G A    +  
Sbjct: 2347 -----GHGQ-----ASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSH 2396

Query: 357  STSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQK 416
              S  G ++     S S  +  S      +A    G + G    +   +   S R  + +
Sbjct: 2397 QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQ 2456

Query: 417  VSQ------PSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSA 470
              Q      P +          E+         SHH     SH    G  +       S 
Sbjct: 2457 EGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHH-----SHTTSQGRSDASHGHSGSR 2511

Query: 471  SGHKNTRDDKKEKGYSNVRGKRH---GSSRKSSTHSST----KKESRTTQELGKNQSASS 523
            S  + TR+D++    S   G RH    S   SS HS       +  RT++  G + S  S
Sbjct: 2512 SASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDS 2571



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 79/377 (20%), Positives = 126/377 (33%), Gaps = 35/377 (9%)

Query: 190  SGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAAS 249
            SG    E++    AA  H +   S    +      +A SS ++G        HG AS+A 
Sbjct: 3598 SGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG------IGHGQASSAV 3651

Query: 250  PSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQV 309
              +   G++   A+ + G    + T +     V+  G A             +SAG    
Sbjct: 3652 RDSGHRGSSGSQASDSEGHSEDSDTQS-----VSAHGQAGPHQQSHQESTRGRSAG---- 3702

Query: 310  TTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQD 369
             +  +G+ +     +E S+S  G A  S+ G         S   +   +S   A+   QD
Sbjct: 3703 RSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQ------GSRHEQARDSSRHSASQEGQD 3756

Query: 370  SSLS--AAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNE 427
            +      +  G    S            G   S   S+G      G       S E  NE
Sbjct: 3757 TIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNE 3816

Query: 428  NKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSN 487
              E+     RH   +        +S R     + + A S RS     +   D   + Y  
Sbjct: 3817 --EQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPE 3874

Query: 488  VRGKR--------HGSSRKSSTHSSTKKES--RTTQELGKNQSASSTGALQKKASKISSF 537
               +R        HGSSR+ S   S    S  R T    ++    S  +  K+    SS 
Sbjct: 3875 DSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSL 3934

Query: 538  LRSLRATPGSKTRVTSH 554
             +      G ++R + H
Sbjct: 3935 SQDSAYHSGIQSRGSPH 3951



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 70/305 (22%), Positives = 109/305 (35%), Gaps = 49/305 (16%)

Query: 304  AGPGQVTTALAGAAIKNPGENESSKSMAGAAN--ISSEGISLALVGAASTSLEGTSTSMA 361
            A  GQ  +  A    +N  ++      +G+ +   SS         A     EG+ TS  
Sbjct: 882  ASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRR 941

Query: 362  GAASLSQDSSL------SAAFAGSITTSK--CAAERTEGPAVGPLISTLQSEGYMSERDG 413
              +S+SQDS        S  ++GS + +    A E++   +  P        G+    D 
Sbjct: 942  QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADS 1001

Query: 414  SQKVSQPSAE-------VWNENKERREKKDRHPSR-----KSSHH----RKAGESHRRRA 457
            S++   P AE         +  + R    +RH SR      SS H    R+   S  R +
Sbjct: 1002 SRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDS 1061

Query: 458  GDKNQKASSHRSASGHKNTRDDKKEKG-----------------YSNVRGKRHGS-SRKS 499
            G      S    + GH    D +   G                 +S  R  R GS   + 
Sbjct: 1062 GHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQV 1121

Query: 500  STH-SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLR-SLRATPGSK---TRVTSH 554
            STH  S     RT    G+ Q +    A        S   + ++RA PGS+    + + H
Sbjct: 1122 STHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHH 1181

Query: 555  DREVD 559
            ++ VD
Sbjct: 1182 EQSVD 1186



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 81/381 (21%), Positives = 136/381 (35%), Gaps = 71/381 (18%)

Query: 225  AATSSAYAGGEGIQHASHG-TASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283
            +A SS  +G    + +S G  AS+   + S+PG   G   + +   +   + TG R D +
Sbjct: 1646 SAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSST-DSGTGRRQDSS 1704

Query: 284  IAGAA---------------MSPATGAMSIATTKSAGPGQVT------------TALAGA 316
            + G +                S  +   S++    AGP Q +            +  +G+
Sbjct: 1705 VVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGS 1764

Query: 317  AIKNPGENESSKSMAGAANISSEGISLALVGAA------STSLEGTST-------SMAGA 363
             +     +E S+S  G    S+ G   +    A      S S EG  T       S  G 
Sbjct: 1765 FLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGR 1824

Query: 364  ASLSQDSSL-SAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSA 422
                 + S+ S+  +GS  +   + ER++       +S  QS        GS+ VS+ + 
Sbjct: 1825 QGSHYEQSVDSSGHSGSHHSHTTSQERSD-------VSRGQS--------GSRSVSRQTR 1869

Query: 423  EVWNENKERREKKDRHPSRKS----SHHRKAGE---SHRRRAGDKNQKASSHRSASGHKN 475
                     R    RH    S    S H + G+   S  R + ++    S    + GH  
Sbjct: 1870 NEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSE 1929

Query: 476  TRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535
              +        N  G     SR  S H  +  E R     G   SA S+     + ++ S
Sbjct: 1930 DSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRA----GHGHSADSSRQSGTRHTESS 1985

Query: 536  SFLRSLRATPGSKTRVTSHDR 556
            S  R   A+   + R ++ +R
Sbjct: 1986 S--RGQAASSHEQARSSAGER 2004



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 56/283 (19%), Positives = 109/283 (38%), Gaps = 30/283 (10%)

Query: 240  ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299
            A HG ++ +S  + T         + A     A ++ G R       +A S     +   
Sbjct: 2938 AGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI--- 2994

Query: 300  TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359
                 G GQ ++A+  +  +    +++S +   + +  ++ +S    G A +  +    S
Sbjct: 2995 -----GHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH--GQAGSHQQSHQES 3047

Query: 360  MAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQ 419
              G +   + S  S +F   ++T +  +E + G   GP  ST   +G  S  + +Q  S+
Sbjct: 3048 ARGRSG--ETSGHSGSFLYQVSTHE-QSESSHG-WTGP--STRGRQG--SRHEQAQDSSR 3099

Query: 420  PSAEVWNENKERREKKDRHPSRKSSHHRK---------AGESHRRRAGDKNQKASSHRSA 470
             SA  + ++  R         R+  HH           +  SH    G  +       S 
Sbjct: 3100 HSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR 3159

Query: 471  SGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQ 513
            S  + TR++++    S     RH    ++STH+   + S+  Q
Sbjct: 3160 SASRTTRNEEQSGDSSRHSVSRH---HEASTHADISRHSQAVQ 3199



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 34/163 (20%), Positives = 63/163 (38%), Gaps = 10/163 (6%)

Query: 403  QSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQ 462
            QS G  + R+    VSQ S     +++   E  +R     S +HR  G +  +       
Sbjct: 3525 QSAGPRTSRNQGSSVSQDS-----DSQGHSEDSERWSGSASRNHR--GSAQEQSRDGSRH 3577

Query: 463  KASSHRSASGHKNTRDDKKEKG---YSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQ 519
              S H   +GH ++ +  ++ G     N  G +  SS + +  S+ ++     Q+   + 
Sbjct: 3578 PTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 3637

Query: 520  SASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
              S  G  Q  ++   S  R    +  S +   S D +   V+
Sbjct: 3638 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS 3680



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 29/122 (23%), Positives = 47/122 (38%), Gaps = 10/122 (8%)

Query: 409  SERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHR 468
            S R GS       +E + E+ ERR +     S   +HH   G S  +         SSHR
Sbjct: 3856 SRRQGSSVSQDSDSEAYPEDSERRSE-----SASRNHH---GSSREQSRDGSRHPGSSHR 3907

Query: 469  SASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQ 528
              + H  +   + +   +   G     S+ S+ HS    +SR +     +    S G  +
Sbjct: 3908 DTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGI--QSRGSPHSSSSYHYQSEGTER 3965

Query: 529  KK 530
            +K
Sbjct: 3966 QK 3967



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 35/123 (28%), Positives = 51/123 (41%), Gaps = 29/123 (23%)

Query: 403  QSEGYMSERDGSQKVSQPS--------AEVWNEN---------KERREKKDRHPSRKSSH 445
            QSEG    R     VSQ S        +E W+ +         +E+     RHP  +S  
Sbjct: 2877 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP--RSHQ 2934

Query: 446  HRKAGESH----RRRAGDKN-QKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSS 500
              +AG  H     R++G ++ Q +S  ++AS H+  R    E+      G  H  S  SS
Sbjct: 2935 EDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGER-----HGSHHQQSADSS 2989

Query: 501  THS 503
             HS
Sbjct: 2990 RHS 2992



 Score = 33.9 bits (76), Expect = 0.44
 Identities = 64/344 (18%), Positives = 118/344 (34%), Gaps = 31/344 (9%)

Query: 190  SGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAG------GEGIQHASHG 243
            SG    E +    AA  H +   S    +      +A SS ++G         ++ + H 
Sbjct: 3274 SGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHW 3333

Query: 244  TASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA---IAGAAMSPATGAMSIAT 300
              S+ S ++ + G +E    ++  G   AG       + A     G +    +    ++T
Sbjct: 3334 -GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVST 3392

Query: 301  TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM 360
             + +      T  +    +     ++  S   +A+   +       G++    +G+    
Sbjct: 3393 HEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQ 3452

Query: 361  AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420
                  S D S  +    S TTS+  ++ + G + G   ++ Q+       DGS+     
Sbjct: 3453 ------SVDRSGHSGSHHSHTTSQGRSDASRGQS-GSRSASRQTRNDEQSGDGSR----- 3500

Query: 421  SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480
                W+ + E   + D     +S   + AG    R  G      S    + GH    +  
Sbjct: 3501 --HSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSS---VSQDSDSQGHSEDSERW 3555

Query: 481  KEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASST 524
                  N RG     SR  S H ++  E R     G   SA S+
Sbjct: 3556 SGSASRNHRGSAQEQSRDGSRHPTSHHEDRA----GHGHSAESS 3595



 Score = 33.1 bits (74), Expect = 0.76
 Identities = 33/164 (20%), Positives = 62/164 (37%), Gaps = 11/164 (6%)

Query: 403  QSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQ 462
            QS G  + R+    VSQ S     +++   E  +R     S +H   G +  +       
Sbjct: 1904 QSSGPRTSRNQGSSVSQDS-----DSQGHSEDSERWSGSASRNH--LGSAWEQSRDGSRH 1956

Query: 463  KASSHRSASGHKNTRDDKKEKG----YSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKN 518
              S H   +GH ++ D  ++ G     S+ RG+   S  ++ + +  +  S    +   +
Sbjct: 1957 PGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADS 2016

Query: 519  QSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562
               S  G  Q  ++   S  R    +  S +   S D +   V+
Sbjct: 2017 SRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVS 2060



 Score = 33.1 bits (74), Expect = 0.76
 Identities = 66/293 (22%), Positives = 109/293 (37%), Gaps = 44/293 (15%)

Query: 225  AATSSAYA-GGEGIQHASHGTASAASPSTSTPGAAEGGAA-RTAGGMAVAGTAT----GP 278
            AA+S   A    G +H SH   SA S   S  G  +  +A R +G    +G+      G 
Sbjct: 2639 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGH 2698

Query: 279  RTDVAIAGAAMSPATGAMSIATTKSA-GPGQVTTALAGAAIKNPGENESSKSMAGAANIS 337
              D      +     G+   +  +SA G    T+  +G+ +     +E S+S  G    S
Sbjct: 2699 SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 2758

Query: 338  SEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGP 397
            + G             +G+    A      QDSS  +A      T +     + G   G 
Sbjct: 2759 TRG------------RQGSRHEQA------QDSSRHSASQDGQDTIRGHPGSSRGGRQGY 2800

Query: 398  LIS-TLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRR 456
                ++ S G+      S   SQ  ++       R +   R  SR + +  ++G+  R  
Sbjct: 2801 HHEHSVDSSGHSGSHH-SHTTSQGRSDA-----SRGQSGSRSASRTTRNEEQSGDGSRH- 2853

Query: 457  AGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKES 509
            +G ++ +AS+H   S H              V+G+  GS R     SS  ++S
Sbjct: 2854 SGSRHHEASTHADISRHSQA-----------VQGQSEGSRRSRRQGSSVSQDS 2895



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 14/141 (9%)

Query: 355  GTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGS 414
            G+  S    +S+SQDS   A    S   S+ A+    G       S  QS      RDGS
Sbjct: 3852 GSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGS------SREQS------RDGS 3899

Query: 415  QKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHK 474
            +       +  +  +    + D   +++  H     +     +G ++ + S H S+S H 
Sbjct: 3900 RHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQS-RGSPHSSSSYHY 3958

Query: 475  NTRDDKKEKGYSNVRGKRHGS 495
             +   +++KG S +   RHGS
Sbjct: 3959 QSEGTERQKGQSGLVW-RHGS 3978



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 13/170 (7%)

Query: 367  SQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEV-- 424
            S D S  +    S TTS+  ++ + G + G   ++ Q+       DGS+       E   
Sbjct: 1184 SVDRSGHSGSHHSHTTSQGRSDASHGQS-GSRSASRQTRKDKQSGDGSRHSGSRHHEAAS 1242

Query: 425  WNENKERREK-KDRHPSRKSSHHRKAG---ESHRRRAGDKNQKASSHRSASGH----KNT 476
            W ++    +  +++    ++S H+ +    +S   R  D +++ S   S + H    + +
Sbjct: 1243 WADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQS 1302

Query: 477  RDDKKEKGYSNVRGKRHGSSRKSSTHSST--KKESRTTQELGKNQSASST 524
            RD  +  G+       HG S  SS  S T   + S   Q +  ++ A S+
Sbjct: 1303 RDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSS 1352



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 41/171 (23%), Positives = 71/171 (41%), Gaps = 19/171 (11%)

Query: 381 TTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS 440
           ++S+    R E  +  PL      E    +R GS +VSQ       +++   E  +RH  
Sbjct: 267 SSSQVNRSRHENTSQVPL-----QESRTRKRRGS-RVSQD-----RDSEGHSEDSERHSG 315

Query: 441 RKS-SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKS 499
             S +HH  A E  + R G ++ ++     AS H ++ D  ++ G  +      G +  +
Sbjct: 316 SASRNHHGSAWE--QSRDGSRHPRSHDEDRAS-HGHSADSSRQSGTRHAETSSRGQT--A 370

Query: 500 STHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFL--RSLRATPGSK 548
           S+H   +         G  QSA S+        + SS +  R  R + GS+
Sbjct: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 72/330 (21%), Positives = 123/330 (37%), Gaps = 50/330 (15%)

Query: 225  AATSSAYA-GGEGIQHASHGTASAASPSTSTPGAAEGGAA-RTAGGMAVAGTAT----GP 278
            AA+S   A    G +H SH   SA S   S  G  +  +A R +G    +G+      G 
Sbjct: 2963 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGH 3022

Query: 279  RTDVAIAGAAMSPATGAMSIATTKSA-GPGQVTTALAGAAIKNPGENESSKSMAGAANIS 337
              D      +     G+   +  +SA G    T+  +G+ +     +E S+S  G    S
Sbjct: 3023 SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 3082

Query: 338  SEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGP 397
            + G             +G+    A      QDSS  +A      T +     + G   G 
Sbjct: 3083 TRG------------RQGSRHEQA------QDSSRHSASQYGQDTIRGHPGSSRGGRQGY 3124

Query: 398  LIS-TLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRR 456
                ++ S G+      S   SQ  ++       R +   R  SR + +  ++G+S R  
Sbjct: 3125 HHEHSVDSSGHSGSHH-SHTTSQGRSDA-----SRGQSGSRSASRTTRNEEQSGDSSRHS 3178

Query: 457  AGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE------SR 510
               ++ +AS+H   S H              V+G+  GS R     SS  ++      S 
Sbjct: 3179 VS-RHHEASTHADISRHSQA-----------VQGQSEGSRRSRRQGSSVSQDSDSEGHSE 3226

Query: 511  TTQELGKNQSASSTGALQKKASKISSFLRS 540
             ++    + S +  G++Q+++   S   RS
Sbjct: 3227 DSERWSGSASRNHRGSVQEQSRHGSRHPRS 3256



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 34/161 (21%), Positives = 60/161 (37%), Gaps = 18/161 (11%)

Query: 401 TLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDK 460
           +L  E  + ER  S    + S++V   N+ R E   + P ++S   ++ G          
Sbjct: 249 SLLEENKIYERSRSSD-GKSSSQV---NRSRHENTSQVPLQESRTRKRRGS--------- 295

Query: 461 NQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQS 520
             + S  R + GH    +        N  G     SR  S H  +  E R +     + S
Sbjct: 296 --RVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSS 353

Query: 521 ASSTGALQKKASK--ISSFLRSLRATPGSKTRVTSHDREVD 559
             S     + +S+   +S     R++PG +   + H +  D
Sbjct: 354 RQSGTRHAETSSRGQTASSHEQARSSPGER-HGSGHQQSAD 393



 Score = 29.6 bits (65), Expect = 8.4
 Identities = 67/330 (20%), Positives = 105/330 (31%), Gaps = 50/330 (15%)

Query: 225  AATSSAYA-GGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283
            AA+S   A    G +H SH    +A  S  + G   G A+         G +    +D  
Sbjct: 1990 AASSHEQARSSAGERHGSHHQLQSADSSRHS-GIGHGQASSAVRDSGHRGYSGSQASD-- 2046

Query: 284  IAGAAMSPATGAMSIATTKSAGPGQVT------------TALAGAAIKNPGENESSKSMA 331
                  S  +   S++    AGP Q +            +  +G+ +     +E S+S  
Sbjct: 2047 --SEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTH 2104

Query: 332  GAANISSEGISLALVGAA------STSLEGTST-------SMAGAASLSQDSSLS-AAFA 377
            G +  S+ G   +    A      S S EG  T       S  G     Q+ S+  +  +
Sbjct: 2105 GQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHS 2164

Query: 378  GSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDR 437
            GS  +   +  R++            S G    R  S+K                   + 
Sbjct: 2165 GSHHSHTTSQGRSDA-----------SRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEA 2213

Query: 438  HPSRKSSHHRKAGE---SHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHG 494
                 SS H   G+   S  R +  +    S    + GH    + +      N  G    
Sbjct: 2214 SSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQE 2273

Query: 495  SSRKSSTHSSTKKESRTTQELGKNQSASST 524
             SR  S H  +  E R     G   SA S+
Sbjct: 2274 QSRDGSRHPRSHHEDRA----GHGHSAESS 2299


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 66/265 (24%), Positives = 100/265 (37%), Gaps = 32/265 (12%)

Query: 278 PRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKS-MAGAANI 336
           P   +A  G A + A  A + ++  S GP      LA    +  G  +  +   AG    
Sbjct: 57  PLLFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAE 116

Query: 337 SSEGISLALV---GAASTSLEGTSTSMAGAASLSQDSSLSAAFAG-SITTSKCAAERTEG 392
                SL      G    S  G  T +     +S  S       G S  T+  AA  T G
Sbjct: 117 KRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGG 176

Query: 393 PAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS--RKSSHHRKAG 450
               P  S+           G+Q+          E  ERR ++DR  S  R    HR+  
Sbjct: 177 SGGSPASSS-----------GTQRRG--------EGSERRPRRDRRSSSGRSKERHRE-- 215

Query: 451 ESHRRRAGDK-NQKASSHRSASGHK-NTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE 508
             HRRR G +   +AS  RS   H    R +  + G S+  G R  S+  +S+ SS++K+
Sbjct: 216 --HRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKD 273

Query: 509 SRTTQELGKNQSASSTGALQKKASK 533
             +     + +S+    +  K+  K
Sbjct: 274 RDSKAHRSRTKSSKEPPSAYKEPPK 298



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 88/396 (22%), Positives = 145/396 (36%), Gaps = 44/396 (11%)

Query: 212 QSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAAR------T 265
           QSE GL      SAAT++  AGG G      G+  + + S+ T    EG   R      +
Sbjct: 152 QSEQGLLLG-GASAATAATAAGGTG------GSGGSPASSSGTQRRGEGSERRPRRDRRS 204

Query: 266 AGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENE 325
           + G +        R D    G+  S +    S      +G  +   A +G++  + G  +
Sbjct: 205 SSGRSKERHREHRRRDGQRGGSEASKSRSRHS-----HSGEERAEVAKSGSSSSSGGRRK 259

Query: 326 SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC 385
           S+ + + +++   +  S A      +S E  S       +  +D +   A+    + S  
Sbjct: 260 SASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPL 319

Query: 386 AAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSH 445
              R + P       +L+S    S   G    S  S  +         ++    SR SS+
Sbjct: 320 GG-RDDSPVSHRASQSLRSRKSPSPAGGGS--SPYSRRLPRSPSPYSRRRSPSYSRHSSY 376

Query: 446 HRKAGESHRRRAGDKNQKASSHRSA----SGHKNTRDDKKEKGYSNVRGKRHGSSRKSST 501
            R    S    +    +++ S  S     SG   +R     + +S  R  RH  SR  S 
Sbjct: 377 ERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSR-HSRSRS-RHRLSRSRSR 434

Query: 502 HSSTKKESRTTQ-----ELGKNQSASSTGALQK-KASKISSFLRSLRA-----------T 544
           HSS    + T +     EL KN+ A +  A +  +A+K +   ++  A           T
Sbjct: 435 HSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTST 494

Query: 545 PGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGG 580
           P      TS         K V+K  IE     + GG
Sbjct: 495 PTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGG 530


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 66/265 (24%), Positives = 100/265 (37%), Gaps = 32/265 (12%)

Query: 278 PRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKS-MAGAANI 336
           P   +A  G A + A  A + ++  S GP      LA    +  G  +  +   AG    
Sbjct: 57  PLLFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAE 116

Query: 337 SSEGISLALV---GAASTSLEGTSTSMAGAASLSQDSSLSAAFAG-SITTSKCAAERTEG 392
                SL      G    S  G  T +     +S  S       G S  T+  AA  T G
Sbjct: 117 KRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGG 176

Query: 393 PAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS--RKSSHHRKAG 450
               P  S+           G+Q+          E  ERR ++DR  S  R    HR+  
Sbjct: 177 SGGSPASSS-----------GTQRRG--------EGSERRPRRDRRSSSGRSKERHRE-- 215

Query: 451 ESHRRRAGDK-NQKASSHRSASGHK-NTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE 508
             HRRR G +   +AS  RS   H    R +  + G S+  G R  S+  +S+ SS++K+
Sbjct: 216 --HRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKD 273

Query: 509 SRTTQELGKNQSASSTGALQKKASK 533
             +     + +S+    +  K+  K
Sbjct: 274 RDSKAHRSRTKSSKEPPSAYKEPPK 298



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 88/396 (22%), Positives = 145/396 (36%), Gaps = 44/396 (11%)

Query: 212 QSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAAR------T 265
           QSE GL      SAAT++  AGG G      G+  + + S+ T    EG   R      +
Sbjct: 152 QSEQGLLLG-GASAATAATAAGGTG------GSGGSPASSSGTQRRGEGSERRPRRDRRS 204

Query: 266 AGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENE 325
           + G +        R D    G+  S +    S      +G  +   A +G++  + G  +
Sbjct: 205 SSGRSKERHREHRRRDGQRGGSEASKSRSRHS-----HSGEERAEVAKSGSSSSSGGRRK 259

Query: 326 SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC 385
           S+ + + +++   +  S A      +S E  S       +  +D +   A+    + S  
Sbjct: 260 SASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPL 319

Query: 386 AAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSH 445
              R + P       +L+S    S   G    S  S  +         ++    SR SS+
Sbjct: 320 GG-RDDSPVSHRASQSLRSRKSPSPAGGGS--SPYSRRLPRSPSPYSRRRSPSYSRHSSY 376

Query: 446 HRKAGESHRRRAGDKNQKASSHRSA----SGHKNTRDDKKEKGYSNVRGKRHGSSRKSST 501
            R    S    +    +++ S  S     SG   +R     + +S  R  RH  SR  S 
Sbjct: 377 ERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSR-HSRSRS-RHRLSRSRSR 434

Query: 502 HSSTKKESRTTQ-----ELGKNQSASSTGALQK-KASKISSFLRSLRA-----------T 544
           HSS    + T +     EL KN+ A +  A +  +A+K +   ++  A           T
Sbjct: 435 HSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTST 494

Query: 545 PGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGG 580
           P      TS         K V+K  IE     + GG
Sbjct: 495 PTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGG 530


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.123    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,040,399
Number of Sequences: 37866
Number of extensions: 978744
Number of successful extensions: 8224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 177
Number of HSP's successfully gapped in prelim test: 483
Number of HSP's that attempted gapping in prelim test: 5255
Number of HSP's gapped (non-prelim): 2164
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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