BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|222418633 family with sequence similarity 71, member B [Homo sapiens] (605 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|222418633 family with sequence similarity 71, member B [Homo ... 1187 0.0 gi|23957696 hypothetical protein LOC149647 [Homo sapiens] 503 e-142 gi|23503301 hypothetical protein LOC196472 [Homo sapiens] 241 1e-63 gi|89363024 hypothetical protein LOC161142 [Homo sapiens] 117 3e-26 gi|76253859 hypothetical protein LOC112703 [Homo sapiens] 98 2e-20 gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 92 1e-18 gi|14211935 testes development-related NYD-SP18 [Homo sapiens] 84 3e-16 gi|193083150 hypothetical protein LOC346653 isoform b [Homo sapi... 84 4e-16 gi|149192824 hypothetical protein LOC346653 isoform a [Homo sapi... 76 8e-14 gi|161016767 mucin 21 [Homo sapiens] 64 5e-10 gi|57864582 hornerin [Homo sapiens] 61 3e-09 gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 56 1e-07 gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 56 1e-07 gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 55 1e-07 gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 52 1e-06 gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 52 1e-06 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 52 1e-06 gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 52 2e-06 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 50 8e-06 gi|60097902 filaggrin [Homo sapiens] 49 2e-05 gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 49 2e-05 gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 49 2e-05 >gi|222418633 family with sequence similarity 71, member B [Homo sapiens] Length = 605 Score = 1187 bits (3070), Expect = 0.0 Identities = 605/605 (100%), Positives = 605/605 (100%) Query: 1 MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60 MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV Sbjct: 1 MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60 Query: 61 IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120 IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT Sbjct: 61 IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120 Query: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE Sbjct: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180 Query: 181 SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA 240 SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA Sbjct: 181 SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA 240 Query: 241 SHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIAT 300 SHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIAT Sbjct: 241 SHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIAT 300 Query: 301 TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM 360 TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM Sbjct: 301 TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM 360 Query: 361 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP Sbjct: 361 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420 Query: 421 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK Sbjct: 421 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480 Query: 481 KEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRS 540 KEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRS Sbjct: 481 KEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRS 540 Query: 541 LRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVF 600 LRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVF Sbjct: 541 LRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVF 600 Query: 601 ETKSI 605 ETKSI Sbjct: 601 ETKSI 605 >gi|23957696 hypothetical protein LOC149647 [Homo sapiens] Length = 594 Score = 503 bits (1295), Expect = e-142 Identities = 300/612 (49%), Positives = 396/612 (64%), Gaps = 31/612 (5%) Query: 1 MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEV 60 M+ + LPYYTA S SSMS F T+MG LQRQLY +GEY+IFKYAP+FES+FIQI K+GEV Sbjct: 1 MNADFLLPYYTAQSGSSMSMFDTTMGKLQRQLY-KGEYDIFKYAPIFESDFIQITKRGEV 59 Query: 61 IDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELT 120 IDVHNRVRMVT+GI TSPILPLPDVM+LA+P CE++ G+ K + R+ K LELT Sbjct: 60 IDVHNRVRMVTMGIARTSPILPLPDVMLLARPATGCEEYAGHGQATKRKKRKAAKNLELT 119 Query: 121 RLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVE 180 RLLPL+FV+IS+ DHEKQQLRLK ATGR+ YLQLCP+ DTR+DLF YWEKL+YLLRPP+E Sbjct: 120 RLLPLRFVRISVQDHEKQQLRLKFATGRSCYLQLCPALDTRDDLFAYWEKLIYLLRPPME 179 Query: 181 SYCSTPTLLSGDAP-----PEDNKSLVAAELHREGDQSET---GLYKPCDVSAATSSAYA 232 S ST + + D ED +SL A L +GDQ + L+ +V ATS+AYA Sbjct: 180 SNSSTCGIPAEDMMWMPVFQEDRRSLGAVNLQGKGDQDQVSIQSLHMVSEVCGATSAAYA 239 Query: 233 GGEGIQHASH---GTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAM 289 GGEG+Q+ + +A+ P TST A E GG+ A A A AGAA Sbjct: 240 GGEGLQNDFNKPTNVLNASIPKTSTELAEE----PATGGIKEAAAAG------AAAGAAT 289 Query: 290 SPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAA 349 GA+S+A SA PGQV+ A+AGAA + G N+ + ++AG A+++ +A+ GAA Sbjct: 290 GTVAGALSVAAANSA-PGQVSAAIAGAATIDAGGNKGNMALAGTASMAPNSTKVAVAGAA 348 Query: 350 STSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMS 409 S E S++ + SLS++ S+S A AG + TS+ AAE A GP +ST QS+ +S Sbjct: 349 GKSSEHVSSA---SMSLSREGSVSLAIAGVVLTSRTAAEADMDAAAGPPVSTRQSKSSLS 405 Query: 410 ERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRS 469 + G ++ +Q SAE E +ERRE KDR R SSH R+ GES + GDK + SS RS Sbjct: 406 GQHGRER-TQASAEGCKEGRERRE-KDRALGR-SSHRRRTGESRHKTRGDKIAQKSSSRS 462 Query: 470 ASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQK 529 + H+ RDDKKEKG N RH S K +H+ KESRT+ + G++ +S+G+ K Sbjct: 463 SFSHRANRDDKKEKGCGNPGSSRHRDSHKGVSHTPISKESRTSHKSGRSLWTTSSGS-SK 521 Query: 530 KASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGT 589 ++SSFLR++RA +K T H R+VD++AKM E+ A E A+GGQ LEM+ G+ Sbjct: 522 GLGRVSSFLRNVRANLTTKVVGTPHGRDVDVMAKMAERSTNVAIAETAEGGQGLEMV-GS 580 Query: 590 MTSEKTEMIVFE 601 MT + E + FE Sbjct: 581 MTPDIMETVTFE 592 >gi|23503301 hypothetical protein LOC196472 [Homo sapiens] Length = 241 Score = 241 bits (616), Expect = 1e-63 Identities = 124/191 (64%), Positives = 148/191 (77%), Gaps = 4/191 (2%) Query: 4 ESC--LPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVI 61 E C LPYYTA S +M F TSMG LQRQLY +GEY IF+YAPMFES+FIQI+K+GEVI Sbjct: 2 EDCCMLPYYTAQSSPAMGMFNTSMGKLQRQLY-KGEYTIFRYAPMFESDFIQISKRGEVI 60 Query: 62 DVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTR 121 DVHNR RMVT+GIV TSP L LPDVM+LA+P +C+ + R G + R P + LELTR Sbjct: 61 DVHNRARMVTMGIVRTSPCLTLPDVMLLARPAAVCD-NARCGPATQKRESPPAEILELTR 119 Query: 122 LLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVES 181 LLPL FVKI+IH+ K+QL LKLATGR+FYLQLCP SD EDLF +WE LVY+LRPPVE+ Sbjct: 120 LLPLMFVKITIHNSVKKQLHLKLATGRSFYLQLCPPSDASEDLFVHWENLVYILRPPVEA 179 Query: 182 YCSTPTLLSGD 192 Y T +L+G+ Sbjct: 180 YSDTRAILAGN 190 >gi|89363024 hypothetical protein LOC161142 [Homo sapiens] Length = 422 Score = 117 bits (293), Expect = 3e-26 Identities = 67/149 (44%), Positives = 90/149 (60%), Gaps = 2/149 (1%) Query: 27 DLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDV 86 DLQ L + GEY F PM ESNFIQ+N++GE I +HNR VTVGI +S +P+V Sbjct: 28 DLQNML-DGGEYAPFVSPPMLESNFIQVNRRGESIYLHNRANWVTVGICFSSSTHKIPNV 86 Query: 87 MVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLAT 146 M+LA T ++ F P + L LTR LPL+FV +S+HD E L++KL + Sbjct: 87 MLLAHLTPGAQKDTET-LFKSLLTSPPAEKLVLTRFLPLQFVTLSVHDAENMSLKVKLVS 145 Query: 147 GRTFYLQLCPSSDTREDLFCYWEKLVYLL 175 GR +YLQLC S+ ++ LF W L+ LL Sbjct: 146 GRAYYLQLCTSAYKQDTLFSQWVALISLL 174 >gi|76253859 hypothetical protein LOC112703 [Homo sapiens] Length = 231 Score = 98.2 bits (243), Expect = 2e-20 Identities = 62/149 (41%), Positives = 86/149 (57%), Gaps = 25/149 (16%) Query: 28 LQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVM 87 LQR L + GE++ F+ P+FESNF+Q+ + GEV + VT+G+ +SP L LPD++ Sbjct: 96 LQRYLQS-GEFDQFRDFPIFESNFVQVTRLGEVANE------VTMGVAASSPALELPDLL 148 Query: 88 VLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLATG 147 +LA P AK G L+L L PLKFV++ +HD + QL +KL T Sbjct: 149 LLAGP-------------AKENGH-----LQLFGLFPLKFVQLFVHDKSRCQLEVKLNTS 190 Query: 148 RTFYLQLCPSSDTREDLFCYWEKLVYLLR 176 RTFYLQL TR+ F W +L+Y LR Sbjct: 191 RTFYLQLRAPLKTRDREFGQWVRLLYRLR 219 >gi|223972704 hypothetical protein LOC284418 [Homo sapiens] Length = 922 Score = 92.0 bits (227), Expect = 1e-18 Identities = 52/163 (31%), Positives = 87/163 (53%), Gaps = 17/163 (10%) Query: 25 MGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLP 84 +G+LQ+ L +GEY + PMFESNF+Q+ +G + V++R + +G+ + P L LP Sbjct: 23 LGELQKTL-QKGEYLPLRPLPMFESNFVQVTHQGGPVFVNHRTNRLAMGVAASLPGLVLP 81 Query: 85 DVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKL 144 D++++ QP + R L LTR++PL V + +HD +L+L+L Sbjct: 82 DILLIGQPAE----------------DRDCSGLVLTRMIPLDLVHLCVHDLSAWRLKLRL 125 Query: 145 ATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVESYCSTPT 187 +GR +YL L + LF W +L+ LL+ P ++ T Sbjct: 126 VSGRQYYLALDAPDNEVGFLFHCWVRLINLLQEPAPTWTPRTT 168 >gi|14211935 testes development-related NYD-SP18 [Homo sapiens] Length = 344 Score = 84.3 bits (207), Expect = 3e-16 Identities = 48/155 (30%), Positives = 86/155 (55%), Gaps = 12/155 (7%) Query: 37 EYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKIC 96 E+N+F + +FESNFIQ+ + DV+ + +G+ + P LPLP+++++A Sbjct: 67 EFNLFLDSVVFESNFIQVKRGRNWRDVYKASNTMALGVTSSVPCLPLPNILLMAS----- 121 Query: 97 EQHVRWGRFAKGRGRRP--VKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQL 154 V+W + RP + L R+LPL+FV++ + DH ++ L+L+ T + +YL+L Sbjct: 122 ---VKWHQGQNQTWNRPSIAPNIFLKRILPLRFVELQVCDHYQRILQLRTVTEKIYYLKL 178 Query: 155 CPSSDTREDLFCYWEKLVYLLRPPVESYCSTPTLL 189 P D E +F +W +LV +L+ + P +L Sbjct: 179 HP--DHPETVFHFWIRLVQILQKGLSITTKDPRIL 211 >gi|193083150 hypothetical protein LOC346653 isoform b [Homo sapiens] Length = 300 Score = 84.0 bits (206), Expect = 4e-16 Identities = 52/146 (35%), Positives = 83/146 (56%), Gaps = 8/146 (5%) Query: 31 QLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVMVLA 90 QL + E+N+F + +FESNFIQ+ K G DV V +G+ + P LPLP+V+++A Sbjct: 29 QLIHSPEFNLFSNSVVFESNFIQVTKPGNWRDVCEGSATVILGVTSSVPSLPLPNVLLMA 88 Query: 91 QPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTF 150 T W G PV + L+RLLPLK+V++ I+D ++ LR++ T + + Sbjct: 89 NVTWPQGPFTTWST----PGDAPV--INLSRLLPLKYVELRIYDRLQRILRVRTVTEKIY 142 Query: 151 YLQLCPSSDTREDLFCYWEKLVYLLR 176 YL+L E +F +W +LV +L+ Sbjct: 143 YLKL--HEKHPEIVFQFWVRLVKILQ 166 >gi|149192824 hypothetical protein LOC346653 isoform a [Homo sapiens] Length = 309 Score = 76.3 bits (186), Expect = 8e-14 Identities = 52/155 (33%), Positives = 83/155 (53%), Gaps = 17/155 (10%) Query: 31 QLYNRGEYNIFKYAPMFESNFIQ---------INKKGEVIDVHNRVRMVTVGIVCTSPIL 81 QL + E+N+F + +FESNFIQ + K G DV V +G+ + P L Sbjct: 29 QLIHSPEFNLFSNSVVFESNFIQTHVPEADFQVTKPGNWRDVCEGSATVILGVTSSVPSL 88 Query: 82 PLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLR 141 PLP+V+++A T W G PV + L+RLLPLK+V++ I+D ++ LR Sbjct: 89 PLPNVLLMANVTWPQGPFTTWST----PGDAPV--INLSRLLPLKYVELRIYDRLQRILR 142 Query: 142 LKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLR 176 ++ T + +YL+L E +F +W +LV +L+ Sbjct: 143 VRTVTEKIYYLKL--HEKHPEIVFQFWVRLVKILQ 175 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 63.5 bits (153), Expect = 5e-10 Identities = 77/365 (21%), Positives = 143/365 (39%), Gaps = 19/365 (5%) Query: 184 STPTLLSGDAPPEDNKSLVA-AELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASH 242 ST T+ SG + + S+V +E H T ++ S E S Sbjct: 58 STATI-SGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSES-STTSS 115 Query: 243 GTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTK 302 G ++A + +STP + A + +G +T +D + + S AT + S T+ Sbjct: 116 GASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSS 175 Query: 303 SAGPG---QVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359 A + +T + A+ E+ ++ S A A +SE + + +T+ E ++TS Sbjct: 176 GASTATNSESSTVSSRASTATNSESSTTSSGASTAT-NSESRTTSNGAGTATNSESSTTS 234 Query: 360 MAGAASLSQDSSLSAAFAGSITTSKCA--------AERTEGPAVGPLISTLQSEGYMSER 411 + + + +SS ++ AG+ T S+ + A +E V IST+ + + Sbjct: 235 SGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPS 294 Query: 412 DGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSAS 471 G+ + + + D + + ES +G S + S Sbjct: 295 SGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTS 354 Query: 472 GHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKA 531 +T + S+ G ++ +SST SS + TT E S +ST A ++ Sbjct: 355 SGASTATNSGSSTTSS--GTSTATNSESSTVSS-GASTATTSESSTTSSGAST-ATNSES 410 Query: 532 SKISS 536 S +SS Sbjct: 411 STVSS 415 Score = 58.9 bits (141), Expect = 1e-08 Identities = 75/338 (22%), Positives = 129/338 (38%), Gaps = 22/338 (6%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283 S+ S+A + TA+ + ST++ GA+ + ++ + A TAT + Sbjct: 144 SSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTT 203 Query: 284 IAGAAMSPATGAMSIATTKSAGP---GQVTTALAGAAIKNPGENESSKSMAGAA-----N 335 +GA S AT + S T+ AG + +T +GA+ E+ + S AG A + Sbjct: 204 SSGA--STATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESS 261 Query: 336 ISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAV 395 +S G A +ST G ST +S + +A + S TTS A T + Sbjct: 262 TTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDS- 320 Query: 396 GPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRR 455 ST S + S S ++ N + S +G S Sbjct: 321 ----STTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTA- 375 Query: 456 RAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQEL 515 N ++S+ S + T + ++ S+ S ++T ES TT Sbjct: 376 ----TNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSS- 430 Query: 516 GKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTS 553 G N +A+++G+ A ++ L + T S + S Sbjct: 431 GAN-TATNSGSSVTSAGSGTAALTGMHTTSHSASTAVS 467 Score = 53.9 bits (128), Expect = 4e-07 Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 14/221 (6%) Query: 181 SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA 240 S STP+ +G A ++ + + +S T V+ + SS + G Sbjct: 243 SESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATN 302 Query: 241 SHG--------TASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPA 292 S TA+ + ST++ GA+ + ++ + A TAT + +GA+ + Sbjct: 303 SESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATN 362 Query: 293 TGAMSIAT-TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANIS-----SEGISLALV 346 +G+ + ++ T +A + +T +GA+ E+ ++ S A A S S G S A Sbjct: 363 SGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATN 422 Query: 347 GAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 +ST+ G +T+ +S++ S +AA G TTS A+ Sbjct: 423 SESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSAS 463 Score = 33.5 bits (75), Expect = 0.58 Identities = 49/285 (17%), Positives = 94/285 (32%), Gaps = 29/285 (10%) Query: 326 SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQ------DSSLSAAFAGS 379 SS +GA+ ++ G S+ G ++ ++ G+S + G + ++ S +S A Sbjct: 35 SSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSE 94 Query: 380 ITTSKCA---AERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKD 436 +T A +E ST + + G+ + + + D Sbjct: 95 FSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSD 154 Query: 437 RHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSS 496 + + ES +G S + S +T + + S+ Sbjct: 155 SSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSE------------SST 202 Query: 497 RKSSTHSSTKKESRTTQE-----LGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRV 551 S ++T ESRTT S +S+GA S+ S+ S++ Sbjct: 203 TSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESST 262 Query: 552 TSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTE 596 TS A E + + + + SG T+ +E Sbjct: 263 TSSGAG---TATNSESSTVSSGISTVTNSESSTPSSGANTATNSE 304 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 61.2 bits (147), Expect = 3e-09 Identities = 79/317 (24%), Positives = 120/317 (37%), Gaps = 28/317 (8%) Query: 224 SAATSSAYAG-GEGIQHAS----HGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGP 278 S+ SS Y G G H+S HG+ S S + G++ G ++ + + + G Sbjct: 937 SSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGH 996 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 + +G + SP+ G + +S+ G + ++ + P E+ S S S Sbjct: 997 GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESR 1056 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPL 398 G S S+S G S++ S S SS S S + G + Sbjct: 1057 SGQSSGYGQHGSSS--GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS---- 1110 Query: 399 ISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS---RKSS---HHRKAGES 452 QS GY R GS P + RH S R SS H GES Sbjct: 1111 ----QSSGY--GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGES 1164 Query: 453 ----HRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE 508 H + ++ S H S SGH + + + RG+RHGSS SS+H + Sbjct: 1165 SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG-QHG 1223 Query: 509 SRTTQELGKNQSASSTG 525 S + Q G + S +G Sbjct: 1224 SGSRQSSGHGRQGSGSG 1240 Score = 60.8 bits (146), Expect = 3e-09 Identities = 78/330 (23%), Positives = 116/330 (35%), Gaps = 35/330 (10%) Query: 207 HREGDQSETGLYKPCDVSAATSSAYAG-GEGIQHASHGTASAASPSTSTPGAAEGGAART 265 H E ++ Y + SS Y G +S G +S +S+ G +R Sbjct: 1169 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 1228 Query: 266 AGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENE 325 + G G+ +G SP+ G S+ GQ + ++ + P E+ Sbjct: 1229 SSGHGRQGSGSGH-----------SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1277 Query: 326 SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC 385 S S + S G S A S S G S S S SS S S Sbjct: 1278 SGHSSVFGQHESGSGHSSAYSQHGSGS--GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1335 Query: 386 AAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS----- 440 R G + QS GY R G+ PS +H S Sbjct: 1336 YGHRGSGSS--------QSSGY--GRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 1385 Query: 441 RKSSHH-----RKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGS 495 S H + +G H + ++ + H S SGH ++ + + + RG+RHGS Sbjct: 1386 SSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGS 1445 Query: 496 SRKSSTHSSTKKESRTTQELGKNQSASSTG 525 S SS+ S + S + Q LG Q S +G Sbjct: 1446 SSGSSS-SYGQHGSGSRQSLGHGQHGSGSG 1474 Score = 59.7 bits (143), Expect = 8e-09 Identities = 78/317 (24%), Positives = 121/317 (38%), Gaps = 30/317 (9%) Query: 224 SAATSSAYAG-GEGIQHAS----HGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGP 278 S+ SS+Y+ G G H+S HG+ S S G++ G ++R G +G+ Sbjct: 2113 SSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY--GQHGSGSRQSS 2170 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 +G+ SP+ G + S+ GQ + ++ + P E+ S S + S Sbjct: 2171 GHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 2230 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPL 398 G S A S S G S S S SS S S + G + Sbjct: 2231 SGHSSAYSQHGSGS--GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSS---- 2284 Query: 399 ISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS-----RKSSHH-----RK 448 QS Y + GS + PS +H S S H + Sbjct: 2285 ----QSSSYGQQGSGSGQ--SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQS 2338 Query: 449 AGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE 508 +G H + ++ + H S SGH ++ + + + RG+RHGSS SS+ S + Sbjct: 2339 SGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSS-SYGQHG 2397 Query: 509 SRTTQELGKNQSASSTG 525 S + Q LG Q S +G Sbjct: 2398 SGSRQSLGHGQHGSGSG 2414 Score = 58.9 bits (141), Expect = 1e-08 Identities = 70/294 (23%), Positives = 110/294 (37%), Gaps = 29/294 (9%) Query: 232 AGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSP 291 + G + HG+ S S G+ G + + G +G+ +G+ S Sbjct: 2386 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSS 2445 Query: 292 ATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST 351 + G + S+G G E+ S +S + SS G S ST Sbjct: 2446 SRGPYESGSGHSSGLGH-------------RESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492 Query: 352 SLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSER 411 S + +S GA+S Q SS +GS S+ + +G G QS G+ Sbjct: 2493 SGQSSSCGQHGASS-GQSSSHGQHGSGS---SQSSGYGRQGSGSG------QSPGHGQRG 2542 Query: 412 DGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSAS 471 GS++ PS R +H S +G H + ++ S H S S Sbjct: 2543 SGSRQ--SPSYGRHGSGSGRSSSSGQHGSGLGE---SSGFGHHESSSGQSSSYSQHGSGS 2597 Query: 472 GHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTG 525 GH + + + RG+RHGSS SS+H + S + Q G + S +G Sbjct: 2598 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG-QHGSGSRQSSGHGRQGSGSG 2650 Score = 58.5 bits (140), Expect = 2e-08 Identities = 72/297 (24%), Positives = 112/297 (37%), Gaps = 34/297 (11%) Query: 232 AGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSP 291 + G + HG+ S S G+ G + + G +G+ +G+ S Sbjct: 1446 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSS 1505 Query: 292 ATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST 351 + G ++ S+G G E+ S +S + SS G S ST Sbjct: 1506 SRGPYESGSSHSSGLGH-------------RESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552 Query: 352 SLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSER 411 S + +S GA+S Q SS +GS S+ + +G G QS G+ Sbjct: 1553 SGQSSSCGQHGASS-GQSSSHGQHGSGS---SQSSGYGRQGSGSG------QSPGHGQRG 1602 Query: 412 DGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSAS 471 GS++ PS R +H S +G H + ++ S H S S Sbjct: 1603 SGSRQ--SPSYGRHGSGSGRSSSSGQHGSGLGE---SSGFGHHESSSGQSSSYSQHGSGS 1657 Query: 472 GHKNTRDDKKEKGYSNVRGKRHGSSRKSST----HSSTKKES--RTTQELGKNQSAS 522 GH + + + RG+RHGSS +SS+ H S ++S Q G QS S Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPS 1714 Score = 56.2 bits (134), Expect = 8e-08 Identities = 75/330 (22%), Positives = 116/330 (35%), Gaps = 35/330 (10%) Query: 207 HREGDQSETGLYKPCDVSAATSSAYAG-GEGIQHASHGTASAASPSTSTPGAAEGGAART 265 H E ++ Y + SS Y G +S G +S +S+ G +R Sbjct: 1639 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQ 1698 Query: 266 AGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENE 325 + G G+ +G SP+ G S+ GQ + ++ + P E+ Sbjct: 1699 SSGHGRQGSGSG-----------QSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR 1747 Query: 326 SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC 385 S S + S G S A S S G S S S SS S S Sbjct: 1748 SGHSSVFGQHESGSGHSSAYSQHGSGS--GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 1805 Query: 386 AAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS----- 440 + G + QS Y + GS + PS +H S Sbjct: 1806 HGQHGSGSS--------QSSSYGQQGSGSGQ--SPSRGRHGSGSGHSSSYGQHGSGSGWS 1855 Query: 441 RKSSHH-----RKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGS 495 S H + +G H + ++ + H S SGH ++ + + + RG++HGS Sbjct: 1856 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGS 1915 Query: 496 SRKSSTHSSTKKESRTTQELGKNQSASSTG 525 S SS+ S + S + Q LG Q S +G Sbjct: 1916 SSGSSS-SYGQHGSGSRQSLGHGQHGSGSG 1944 Score = 55.5 bits (132), Expect = 1e-07 Identities = 73/312 (23%), Positives = 112/312 (35%), Gaps = 23/312 (7%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283 S T G + HG+ S S G++ G ++ + + + G + Sbjct: 1882 SGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1941 Query: 284 IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISL 343 +G + SP+ G + +S+ G + ++ + P E+ S S S G S Sbjct: 1942 GSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS 2001 Query: 344 ALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQ 403 S+S G S++ S S SS S S + G + Q Sbjct: 2002 GYGQHGSSS--GHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS--------Q 2051 Query: 404 SEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS---RKSS---HHRKAGES----H 453 S GY R GS P + RH S R SS H GES H Sbjct: 2052 SSGY--GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGH 2109 Query: 454 RRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQ 513 + ++ S H S SGH + + + RG+RHGSS SS+ + S + Q Sbjct: 2110 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYG-QHGSGSRQ 2168 Query: 514 ELGKNQSASSTG 525 G + S +G Sbjct: 2169 SSGHGRQGSGSG 2180 Score = 50.1 bits (118), Expect = 6e-06 Identities = 76/336 (22%), Positives = 127/336 (37%), Gaps = 31/336 (9%) Query: 205 ELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHAS----HGTAS----------AASP 250 + H G +G + S +S G G H+S HG+ S ++S Sbjct: 219 DTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSG 278 Query: 251 STSTPGAAEGGAARTAG-GMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQV 309 S+S+ G G+ ++ G G +G+ P +G+ S + G ++ S G Sbjct: 279 SSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHY 338 Query: 310 TTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQD 369 + G++ES S G S G+ +S +G S +G AS S Sbjct: 339 ESG--SGQTSGFGQHESGSGQ-------SSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQ 389 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 S+ + S + A+ + G S QS G+ GS + PS+ Sbjct: 390 HGSSSRQSSSYGQHESASRHSSGRGQHSSGSG-QSPGHGQRGSGSGQ--SPSSGQHGTGF 446 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 R + S +G H + + + + H S SGH + + + R Sbjct: 447 GRSSSSGPYVSGSGY---SSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSR 503 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTG 525 G+R GSS SS+ S + S + Q LG ++ S +G Sbjct: 504 GERQGSSAGSSS-SYGQHGSGSRQSLGHSRHGSGSG 538 Score = 50.1 bits (118), Expect = 6e-06 Identities = 73/314 (23%), Positives = 113/314 (35%), Gaps = 41/314 (13%) Query: 210 GDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGM 269 G S +G + D S+ SS+Y E H + G S S +PG + G Sbjct: 849 GQSSSSGQH---DSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRG-------- 897 Query: 270 AVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKS 329 +G+ P +G+ S ++G + +S+G G +++ + G S S Sbjct: 898 --SGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSG-SGHS 954 Query: 330 MAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAER 389 + + S G S S+S G+S+S S S+ S S + Sbjct: 955 SSYEQHGSRSGQSSRSEQHGSSS--GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG 1012 Query: 390 TEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKA 449 G G QS Y R GS W+ + R P S H + Sbjct: 1013 RHGSGSG------QSSSYGPYRSGSG---------WSSS--------RGPYESGSGH-SS 1048 Query: 450 GESHRRRAGDKNQKASSHRSASGHKNTRDDK-KEKGYSNVRGKRHGSSRKSSTHSSTKKE 508 G HR ++ H S+SGH +T G S+ G+ SS +SS+H Sbjct: 1049 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG 1108 Query: 509 SRTTQELGKNQSAS 522 S + G+ S S Sbjct: 1109 SSQSSGYGRQGSGS 1122 Score = 47.8 bits (112), Expect = 3e-05 Identities = 80/383 (20%), Positives = 133/383 (34%), Gaps = 18/383 (4%) Query: 190 SGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYA--GGEGIQHASHGTASA 247 S P E S + HRE ++ Y S+ SS + G Q +S G A Sbjct: 1505 SSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564 Query: 248 ASPSTSTPGAAEGGAARTAG-GMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGP 306 +S +S+ G G+++++G G +G+ P +G+ SP+ G + +S+ Sbjct: 1565 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS 1624 Query: 307 GQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASL 366 GQ + L ++ E+ S +S + + + S G S S S + + G++S Sbjct: 1625 GQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSR 1684 Query: 367 S-----QDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP- 420 S Q S S +G + + G + S G G P Sbjct: 1685 SSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY 1744 Query: 421 -SAEVWNENKERREKKDRHPSRKSSHHRKAGE-----SHRRRAGDKN---QKASSHRSAS 471 S + + E H S S H +G H +G + Q+ SS +S Sbjct: 1745 ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1804 Query: 472 GHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKA 531 H + +G G S H S S + + G SS+ Sbjct: 1805 SHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1864 Query: 532 SKISSFLRSLRATPGSKTRVTSH 554 S SS ++ + T H Sbjct: 1865 SGQSSGFGHHESSSWQSSGYTQH 1887 Score = 45.8 bits (107), Expect = 1e-04 Identities = 76/354 (21%), Positives = 127/354 (35%), Gaps = 27/354 (7%) Query: 224 SAATSSAYA-----GGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGP 278 SA +SS+Y + + H+ HG+ S SPS S G ++ G G+ Sbjct: 510 SAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSS 569 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMA----GAA 334 +G+ S G + +S+G GQ ++ ++ + S +S + GA Sbjct: 570 SRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGAT 629 Query: 335 NISSEGISLALVGAASTSLEGTSTSMAG--------AASLSQDSSLSAAFAGSITTSKCA 386 + S G++ +S G S +G + SS +GS +S Sbjct: 630 SGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNG 689 Query: 387 AERT---EGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKS 443 + + G + QS GY GS S + R ++ S S Sbjct: 690 PHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLS 749 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTR-DDKKEKGYSNVRGKRHGSSRKSSTH 502 S + + G + +G Q S SGH +R G+S+ G+ + SS+ Sbjct: 750 SSYGQHGSGSHQSSGHGRQ-----GSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSC 804 Query: 503 SSTKKESRTTQELGKNQSASSTGALQK-KASKISSFLRSLRATPGSKTRVTSHD 555 + S G+++S S G Q AS S +T G + HD Sbjct: 805 GHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHD 858 Score = 43.9 bits (102), Expect = 4e-04 Identities = 80/392 (20%), Positives = 143/392 (36%), Gaps = 55/392 (14%) Query: 181 SYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHA 240 S C SG + +++ R G Q P + ++ G + Sbjct: 621 SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGS 680 Query: 241 SHGTASAASPSTSTPGAAEG-----GAARTAG------------GMAVAGTATG--PRTD 281 G +S+ P S G + G G+ +++G G G+ +G R++ Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740 Query: 282 VAIAGAAMSPATGAMSIATTKSAG-----------PGQVTTALAGAAIKNPGENESSKSM 330 + + +S + G + +S+G P +V + + G++ S S Sbjct: 741 QHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSC 800 Query: 331 AGAA---------------NISSEGISLALVGAAS--TSLEGTSTSMAGAASLSQDSSLS 373 + + + S G + G+AS S +G S +G +S S S Sbjct: 801 SSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSS 860 Query: 374 AAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERRE 433 + + S + A+ G S QS G+ GS + PS R Sbjct: 861 SGQSSSYGQHESASHHASGRGRHGSGSG-QSPGHGQRGSGSGQ--SPSYGRHGSGSGRSS 917 Query: 434 KKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRH 493 RH S + +G H+ +G ++ + H S SGH ++ + + + R ++H Sbjct: 918 SSGRHGSGSG---QSSGFGHKSSSG-QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH 973 Query: 494 GSSRKSSTHSSTKKESRTTQELGKNQSASSTG 525 GSS SS+ S + S + Q LG Q S +G Sbjct: 974 GSSSGSSS-SYGQHGSGSRQSLGHGQHGSGSG 1004 Score = 42.4 bits (98), Expect = 0.001 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 18/366 (4%) Query: 207 HREGDQSETGLYKPCDVSAATSSAYA--GGEGIQHASHGTASAASPSTSTPGAAEGGAAR 264 HRE ++ Y S+ SS + G Q +S G A+S +S+ G G+++ Sbjct: 1992 HRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQ 2051 Query: 265 TAG-GMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGE 323 ++G G +G+ P +G+ SP+ G + +S+ GQ L ++ E Sbjct: 2052 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHE 2111 Query: 324 NESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLS-----QDSSLSAAFAG 378 + S +S + + + S G S S S + + G++S S Q S S +G Sbjct: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171 Query: 379 SITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP--SAEVWNENKERREKKD 436 + G S G G P S + + E Sbjct: 2172 HGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS 2231 Query: 437 RHPSRKSSHHRKAGE-----SHRRRAGDKN---QKASSHRSASGHKNTRDDKKEKGYSNV 488 H S S H +G H +G + Q+ SS +S H + Sbjct: 2232 GHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQ 2291 Query: 489 RGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSK 548 +G G S H S S + + G SS+ S SS ++ Sbjct: 2292 QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 2351 Query: 549 TRVTSH 554 + T H Sbjct: 2352 SGYTQH 2357 Score = 34.7 bits (78), Expect = 0.26 Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 4/112 (3%) Query: 413 GSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASG 472 GS P+ + D H S + +G S + + ++ S H S SG Sbjct: 196 GSGSGQSPNYGQHGSGSGQSSSNDTHGSGSG---QSSGFSQHKSSSGQSSGYSQHGSGSG 252 Query: 473 HKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASST 524 H + + + RG+RH SS SS+ S + S + Q LG + S + Sbjct: 253 HSSGYGQHGSRSGQSSRGERHRSSSGSSS-SYGQHGSGSRQSLGHGRQGSGS 303 Score = 31.2 bits (69), Expect = 2.9 Identities = 60/312 (19%), Positives = 115/312 (36%), Gaps = 9/312 (2%) Query: 229 SAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAG-GMAVAGTATGPRTDVAIAGA 287 ++Y+G Q +S+G ++ S +S G G+ ++ G +G+ D +G+ Sbjct: 170 NSYSG----QSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGS 225 Query: 288 AMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVG 347 S ++ +S+G Q + ++ + S +S G + SS G S + Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285 Query: 348 AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTS--KCAAERTEGPAVGPLIS-TLQS 404 S S + G+ S S + ++S + + + + G S + Q+ Sbjct: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345 Query: 405 EGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKA 464 G+ GS + S S + + S ++S + G S R+ + Q Sbjct: 346 SGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQ-SSSYGQHE 404 Query: 465 SSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASST 524 S+ R +SG + RG G S S H + S ++ SS Sbjct: 405 SASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSG 464 Query: 525 GALQKKASKISS 536 + +S+ SS Sbjct: 465 FGHHESSSEHSS 476 >gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] Length = 1950 Score = 55.8 bits (133), Expect = 1e-07 Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 26/206 (12%) Query: 221 CDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRT 280 C +A T+S +A T +A + T P A A T GT GP T Sbjct: 1492 CSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLT 1551 Query: 281 DVAIAG-----------AAMSPATGAMSIATTKSAG----PGQVTTALAGAAIKNPGENE 325 + G + + TG +S T ++G G V A GAA +N E Sbjct: 1552 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA 1611 Query: 326 SSKSMAGAANISSEGISLALVGAASTSLE-GTSTSMAGAASLSQDSSLSAAFAGSITTSK 384 + ++GA VG ST E G +++G+ +S S++A+ S T+S+ Sbjct: 1612 GTPRVSGAT---------PAVGGGSTPGEAGPGATVSGSTGVSA-GSITASPGASATSSE 1661 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSE 410 + T GP+VG SE SE Sbjct: 1662 SSKSGTTGPSVGGKTGATSSEATSSE 1687 Score = 39.7 bits (91), Expect = 0.008 Identities = 49/195 (25%), Positives = 72/195 (36%), Gaps = 21/195 (10%) Query: 210 GDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTAS------AASPSTS--TPGAAEGG 261 G+ TG+ P A+ + GG + A+ G AS A +P S TP G Sbjct: 1570 GNAGMTGVVSPTVTGASGMAGTTGG--VDAATTGAASENTSERAGTPRVSGATPAVGGGS 1627 Query: 262 AARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNP 321 AG A +TG V+ SP A S ++KS G GA Sbjct: 1628 TPGEAGPGATVSGSTG----VSAGSITASPGASATSSESSKSGTTGPSVGGKTGATSSEA 1683 Query: 322 GENESSKSMAGAANISSEGISLALVGAASTSLEGTS----TSMAGAASLSQDSSLSAAFA 377 +E + G + S+ G + A TS G+S + S S + + Sbjct: 1684 TSSEGMSGVTGQSLGSTAGSDSEI--TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEW- 1740 Query: 378 GSITTSKCAAERTEG 392 G++ T+ A E T G Sbjct: 1741 GNVATTGAAGENTSG 1755 Score = 33.9 bits (76), Expect = 0.44 Identities = 60/250 (24%), Positives = 92/250 (36%), Gaps = 25/250 (10%) Query: 178 PVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGI 237 P S S+ + SG P A + +G+ S A S + + Sbjct: 1653 PGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTS 1712 Query: 238 QHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGA--AMSPATGA 295 S PS +PG GG G +A G A G T A+ ++ T A Sbjct: 1713 FTGSSPPGKLTRPSPGSPGHFSGGTTEW-GNVATTGAA-GENTSGALGSTEGSVEATTSA 1770 Query: 296 MSIAT-----TKSAGPGQVTTALAGAAIKNPGENESS--KSMAGAANISSEGI------- 341 S T T GPG TA++G + +PG + S G A+I + Sbjct: 1771 GSGNTAGTSGTGDTGPG--NTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSG 1828 Query: 342 --SLALVGAASTSLEGT-STSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAV--G 396 SL ++ A T S + ++ +S+ + ++A A +I+ SK T G A G Sbjct: 1829 HDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGG 1888 Query: 397 PLISTLQSEG 406 + S S G Sbjct: 1889 KITSGWSSSG 1898 >gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo sapiens] Length = 2134 Score = 55.8 bits (133), Expect = 1e-07 Identities = 55/206 (26%), Positives = 82/206 (39%), Gaps = 26/206 (12%) Query: 221 CDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRT 280 C +A T+S +A T +A + T P A A T GT GP T Sbjct: 1676 CSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLT 1735 Query: 281 DVAIAG-----------AAMSPATGAMSIATTKSAG----PGQVTTALAGAAIKNPGENE 325 + G + + TG +S T ++G G V A GAA +N E Sbjct: 1736 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA 1795 Query: 326 SSKSMAGAANISSEGISLALVGAASTSLE-GTSTSMAGAASLSQDSSLSAAFAGSITTSK 384 + ++GA VG ST E G +++G+ +S S++A+ S T+S+ Sbjct: 1796 GTPRVSGAT---------PAVGGGSTPGEAGPGATVSGSTGVSA-GSITASPGASATSSE 1845 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSE 410 + T GP+VG SE SE Sbjct: 1846 SSKSGTTGPSVGGKTGATSSEATSSE 1871 Score = 39.7 bits (91), Expect = 0.008 Identities = 49/195 (25%), Positives = 72/195 (36%), Gaps = 21/195 (10%) Query: 210 GDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTAS------AASPSTS--TPGAAEGG 261 G+ TG+ P A+ + GG + A+ G AS A +P S TP G Sbjct: 1754 GNAGMTGVVSPTVTGASGMAGTTGG--VDAATTGAASENTSERAGTPRVSGATPAVGGGS 1811 Query: 262 AARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNP 321 AG A +TG V+ SP A S ++KS G GA Sbjct: 1812 TPGEAGPGATVSGSTG----VSAGSITASPGASATSSESSKSGTTGPSVGGKTGATSSEA 1867 Query: 322 GENESSKSMAGAANISSEGISLALVGAASTSLEGTS----TSMAGAASLSQDSSLSAAFA 377 +E + G + S+ G + A TS G+S + S S + + Sbjct: 1868 TSSEGMSGVTGQSLGSTAGSDSEI--TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEW- 1924 Query: 378 GSITTSKCAAERTEG 392 G++ T+ A E T G Sbjct: 1925 GNVATTGAAGENTSG 1939 Score = 33.9 bits (76), Expect = 0.44 Identities = 60/250 (24%), Positives = 92/250 (36%), Gaps = 25/250 (10%) Query: 178 PVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGI 237 P S S+ + SG P A + +G+ S A S + + Sbjct: 1837 PGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTS 1896 Query: 238 QHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGA--AMSPATGA 295 S PS +PG GG G +A G A G T A+ ++ T A Sbjct: 1897 FTGSSPPGKLTRPSPGSPGHFSGGTTEW-GNVATTGAA-GENTSGALGSTEGSVEATTSA 1954 Query: 296 MSIAT-----TKSAGPGQVTTALAGAAIKNPGENESS--KSMAGAANISSEGI------- 341 S T T GPG TA++G + +PG + S G A+I + Sbjct: 1955 GSGNTAGTSGTGDTGPG--NTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSG 2012 Query: 342 --SLALVGAASTSLEGT-STSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAV--G 396 SL ++ A T S + ++ +S+ + ++A A +I+ SK T G A G Sbjct: 2013 HDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGG 2072 Query: 397 PLISTLQSEG 406 + S S G Sbjct: 2073 KITSGWSSSG 2082 >gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo sapiens] Length = 2134 Score = 55.5 bits (132), Expect = 1e-07 Identities = 57/206 (27%), Positives = 81/206 (39%), Gaps = 26/206 (12%) Query: 221 CDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRT 280 C +A T+S +A T +A + T P A A T GT GP T Sbjct: 1676 CSETAPTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLT 1735 Query: 281 DVAIAGAAMSPA-----------TGAMSIATTKSAG----PGQVTTALAGAAIKNPGENE 325 + G + TG +S T ++G G V A GAA +N E Sbjct: 1736 EPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSER- 1794 Query: 326 SSKSMAGAANISSEGISLALVGAASTSLE-GTSTSMAGAASLSQDSSLSAAFAGSITTSK 384 AG +S E VG ST E G +++G+ +S S++A+ S T+S+ Sbjct: 1795 -----AGTPRVSGE---TPAVGGGSTPGEAGPGATVSGSTGVSA-GSITASPGASATSSE 1845 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSE 410 + T GP+VG SE SE Sbjct: 1846 SSKSGTTGPSVGGKTGATSSEATSSE 1871 Score = 39.7 bits (91), Expect = 0.008 Identities = 49/195 (25%), Positives = 72/195 (36%), Gaps = 21/195 (10%) Query: 210 GDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTAS------AASPSTS--TPGAAEGG 261 G+ TG+ P A+ + GG + A+ G AS A +P S TP G Sbjct: 1754 GNAGMTGVVSPTVTGASGMAGTTGG--VDAATTGAASENTSERAGTPRVSGETPAVGGGS 1811 Query: 262 AARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNP 321 AG A +TG V+ SP A S ++KS G GA Sbjct: 1812 TPGEAGPGATVSGSTG----VSAGSITASPGASATSSESSKSGTTGPSVGGKTGATSSEA 1867 Query: 322 GENESSKSMAGAANISSEGISLALVGAASTSLEGTS----TSMAGAASLSQDSSLSAAFA 377 +E + G + S+ G + A TS G+S + S S + + Sbjct: 1868 TSSEGMSGVTGQSLGSTAGSDSEI--TAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEW- 1924 Query: 378 GSITTSKCAAERTEG 392 G++ T+ A E T G Sbjct: 1925 GNVATTGAAGENTSG 1939 Score = 33.9 bits (76), Expect = 0.44 Identities = 60/250 (24%), Positives = 92/250 (36%), Gaps = 25/250 (10%) Query: 178 PVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGI 237 P S S+ + SG P A + +G+ S A S + + Sbjct: 1837 PGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTS 1896 Query: 238 QHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGA--AMSPATGA 295 S PS +PG GG G +A G A G T A+ ++ T A Sbjct: 1897 FTGSSPPGKLTRPSPGSPGHFSGGTTEW-GNVATTGAA-GENTSGALGSTEGSVEATTSA 1954 Query: 296 MSIAT-----TKSAGPGQVTTALAGAAIKNPGENESS--KSMAGAANISSEGI------- 341 S T T GPG TA++G + +PG + S G A+I + Sbjct: 1955 GSGNTAGTSGTGDTGPG--NTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSG 2012 Query: 342 --SLALVGAASTSLEGT-STSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAV--G 396 SL ++ A T S + ++ +S+ + ++A A +I+ SK T G A G Sbjct: 2013 HDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGG 2072 Query: 397 PLISTLQSEG 406 + S S G Sbjct: 2073 KITSGWSSSG 2082 >gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 49.7 bits (117), Expect = 8e-06 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 8/188 (4%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283 + ++ + A G + + T + + + ST G+ E + AG A + G T A Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGS-EATTSSAAGSEATTTSTEGSETTTA 1186 Query: 284 -IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKN----PGENESSKSMAGAANISS 338 AG+ + A+ A S TT S + TTA + N G S+ S AG+ ++ Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGP--AVG 396 I A++ SLE T+TS+ G+ + + + S A A S T S T+ ++ Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306 Query: 397 PLISTLQS 404 P+ +T S Sbjct: 1307 PITNTPMS 1314 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.1 bits (113), Expect = 2e-05 Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E T Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTAGSETTTA 1216 Query: 393 PAVGPLISTLQSEG 406 G +T + G Sbjct: 1217 STSGSETNTACTTG 1230 Score = 47.8 bits (112), Expect = 3e-05 Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 19/303 (6%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSS----RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKAS 532 E ++ G ++ ++ST SS E+ T +G + +ST +L+ A+ Sbjct: 1209 AG--SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTAT 1266 Query: 533 KIS 535 ++ Sbjct: 1267 SLT 1269 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 42.0 bits (97), Expect = 0.002 Identities = 68/371 (18%), Positives = 137/371 (36%), Gaps = 29/371 (7%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST-----LQSEGYMSERDGSQKVSQPSAEV 424 +++ + + TTS +E T G +T L++ + G+ S +E Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 425 WNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKG 484 + + + + G + S+ S + +T + Sbjct: 1104 -----------------TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146 Query: 485 YSNVRGKRHGSS--RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLR 542 ++ V S+ +++T S+ E+ TT G + +ST + + + + Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206 Query: 543 ATPGSKTRVTS 553 +T GS+T S Sbjct: 1207 STAGSETTTAS 1217 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216 Query: 393 PAVGPLISTLQSEG 406 G ST S G Sbjct: 1217 CTTGSETSTPSSAG 1230 Score = 48.1 bits (113), Expect = 2e-05 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 + + + ++ST SS E+ T +G + +ST +L+ A+ ++ Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1259 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%) Query: 224 SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276 S T+++ AG E G + + T + + + ST + A+ T M T Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150 Query: 277 GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332 T V+ G+ + ++ A S ATT S + TTA AG+ G ++ S +G Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 333 A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372 + ++ SE + ++G A++ SLE T+TS+ G+ + + + Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270 Query: 373 SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404 S A A S T S T+ ++ P+ +T S Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304 Score = 41.2 bits (95), Expect = 0.003 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401 +++ + + TTS +E T G +T Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.5 bits (114), Expect = 2e-05 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 + + + ++ST SS E+ T +G + +ST +L+ A+ ++ Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLT 1259 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216 Query: 393 PAVGPLISTLQSEG 406 G ST S G Sbjct: 1217 CTTGSETSTPSSAG 1230 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 46.6 bits (109), Expect = 7e-05 Identities = 52/214 (24%), Positives = 90/214 (42%), Gaps = 33/214 (15%) Query: 224 SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276 S T+++ AG E G + + T + + + ST + A+ T M T Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150 Query: 277 GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332 T V+ G+ + ++ A S ATT S + TTA AG+ G ++ S +G Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 333 A---------------ANISSEGISLALVGAAST-----SLEGTSTSMAGAASLSQDSSL 372 + ++ SE + ++G+ ST SLE T+TS+ G+ + + + Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITA 1270 Query: 373 SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404 S A A S T S T+ ++ P+ +T S Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304 Score = 41.2 bits (95), Expect = 0.003 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401 +++ + + TTS +E T G +T Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] Length = 1542 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 508 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 566 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 567 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 626 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 627 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 686 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 687 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 744 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 745 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 791 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 792 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 850 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 851 SETIPA----STAGSETTTTTSTEGSETT 875 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 443 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 502 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 503 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 557 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 558 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 617 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 618 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 672 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 673 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 720 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 721 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 776 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 777 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 822 Score = 50.8 bits (120), Expect = 4e-06 Identities = 88/386 (22%), Positives = 151/386 (39%), Gaps = 49/386 (12%) Query: 197 DNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEG----IQHASHGTASAASPST 252 D+K + A+ + SET + P S T+++ G E I+ + TAS A T Sbjct: 13 DSKVITASSM-----SSETTV-APAAGSNTTTASTTGSETTTILIKASETTTASTAGSET 66 Query: 253 STP---GAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAG---- 305 +TP G+ + + + TA T V+ AG+ + A+ A S +T +AG Sbjct: 67 TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETT 126 Query: 306 ----PGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGA-ASTSLEGTSTSM 360 G TT ++ + + +S + SE +++ VG+ +T+ S + Sbjct: 127 TVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT 186 Query: 361 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420 A + + S+ +++ A + +IT S +E T +ST SE GS+ + Sbjct: 187 AASTTGSEMTTVFTAGSETITPSTAGSETT-------TVSTAGSETTTVSTTGSETTTAS 239 Query: 421 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480 +A S + E+ AG + AS+ S + T D K Sbjct: 240 TAH------SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 293 Query: 481 ----KEKGYSNVRGKRHGS--SRKSSTHSSTKKESRTTQELGKNQSASS-------TGAL 527 G+ GS + S+ S T S E K +ASS G+ Sbjct: 294 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSE 353 Query: 528 QKKASKISSFLRSLRATPGSKTRVTS 553 +AS + S ++ +T GS+T S Sbjct: 354 TIRASTVGSETTTV-STTGSETTTAS 378 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1065 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1119 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1120 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1178 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E Sbjct: 1179 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1237 Query: 393 PAVGPLISTLQSEG 406 G ST S G Sbjct: 1238 CTTGSETSTPSSAG 1251 Score = 48.1 bits (113), Expect = 2e-05 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 996 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1055 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1056 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1110 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1111 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1169 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1170 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1229 Query: 477 RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 + + + ++ST SS E+ T +G + +ST +L+ A+ ++ Sbjct: 1230 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1280 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 777 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 836 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 837 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 896 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 897 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 955 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 956 TASTEGSELTTVSTTG 971 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%) Query: 224 SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276 S T+++ AG E G + + T + + + ST + A+ T M T Sbjct: 1112 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1171 Query: 277 GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332 T V+ G+ + ++ A S ATT S + TTA AG+ G ++ S +G Sbjct: 1172 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1231 Query: 333 A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372 + ++ SE + ++G A++ SLE T+TS+ G+ + + + Sbjct: 1232 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1291 Query: 373 SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404 S A A S T S T+ ++ P+ +T S Sbjct: 1292 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1325 Score = 41.2 bits (95), Expect = 0.003 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 887 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 946 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 947 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 1005 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 1006 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1064 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401 +++ + + TTS +E T G +T Sbjct: 1065 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1096 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 243 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 302 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 303 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 352 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 353 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 412 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 413 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 470 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 471 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 522 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 523 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 578 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 579 TE-GSEMTTVSTTGAETTTDSTE 600 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 786 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 845 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 846 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 905 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 906 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 964 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 965 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 1017 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 1018 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1069 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1070 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1124 >gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216 Query: 393 PAVGPLISTLQSEG 406 G ST S G Sbjct: 1217 CTTGSETSTPSSAG 1230 Score = 48.1 bits (113), Expect = 2e-05 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 + + + ++ST SS E+ T +G + +ST +L+ A+ ++ Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1259 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%) Query: 224 SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276 S T+++ AG E G + + T + + + ST + A+ T M T Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150 Query: 277 GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332 T V+ G+ + ++ A S ATT S + TTA AG+ G ++ S +G Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 333 A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372 + ++ SE + ++G A++ SLE T+TS+ G+ + + + Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270 Query: 373 SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404 S A A S T S T+ ++ P+ +T S Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304 Score = 41.2 bits (95), Expect = 0.003 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401 +++ + + TTS +E T G +T Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] Length = 1704 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216 Query: 393 PAVGPLISTLQSEG 406 G ST S G Sbjct: 1217 CTTGSETSTPSSAG 1230 Score = 48.1 bits (113), Expect = 2e-05 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 + + + ++ST SS E+ T +G + +ST +L+ A+ ++ Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1259 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%) Query: 224 SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276 S T+++ AG E G + + T + + + ST + A+ T M T Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150 Query: 277 GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332 T V+ G+ + ++ A S ATT S + TTA AG+ G ++ S +G Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 333 A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372 + ++ SE + ++G A++ SLE T+TS+ G+ + + + Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270 Query: 373 SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404 S A A S T S T+ ++ P+ +T S Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304 Score = 41.2 bits (95), Expect = 0.003 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401 +++ + + TTS +E T G +T Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 49.7 bits (117), Expect = 8e-06 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 8/188 (4%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283 + ++ + A G + + T + + + ST G+ E + AG A + G T A Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGS-EATTSSAAGSEATTTSTEGSETTTA 1186 Query: 284 -IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKN----PGENESSKSMAGAANISS 338 AG+ + A+ A S TT S + TTA + N G S+ S AG+ ++ Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGP--AVG 396 I A++ SLE T+TS+ G+ + + + S A A S T S T+ ++ Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306 Query: 397 PLISTLQS 404 P+ +T S Sbjct: 1307 PITNTPMS 1314 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.1 bits (113), Expect = 2e-05 Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E T Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTAGSETTTA 1216 Query: 393 PAVGPLISTLQSEG 406 G +T + G Sbjct: 1217 STSGSETNTACTTG 1230 Score = 47.8 bits (112), Expect = 3e-05 Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 19/303 (6%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSS----RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKAS 532 E ++ G ++ ++ST SS E+ T +G + +ST +L+ A+ Sbjct: 1209 AG--SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTAT 1266 Query: 533 KIS 535 ++ Sbjct: 1267 SLT 1269 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 42.0 bits (97), Expect = 0.002 Identities = 68/371 (18%), Positives = 137/371 (36%), Gaps = 29/371 (7%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST-----LQSEGYMSERDGSQKVSQPSAEV 424 +++ + + TTS +E T G +T L++ + G+ S +E Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 425 WNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKG 484 + + + + G + S+ S + +T + Sbjct: 1104 -----------------TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146 Query: 485 YSNVRGKRHGSS--RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLR 542 ++ V S+ +++T S+ E+ TT G + +ST + + + + Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206 Query: 543 ATPGSKTRVTS 553 +T GS+T S Sbjct: 1207 STAGSETTTAS 1217 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 49.7 bits (117), Expect = 8e-06 Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 8/188 (4%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283 + ++ + A G + + T + + + ST G+ E + AG A + G T A Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGS-EATTSSAAGSEATTTSTEGSETTTA 1186 Query: 284 -IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKN----PGENESSKSMAGAANISS 338 AG+ + A+ A S TT S + TTA + N G S+ S AG+ ++ Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTA 1246 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGP--AVG 396 I A++ SLE T+TS+ G+ + + + S A A S T S T+ ++ Sbjct: 1247 FIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306 Query: 397 PLISTLQS 404 P+ +T S Sbjct: 1307 PITNTPMS 1314 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.1 bits (113), Expect = 2e-05 Identities = 49/194 (25%), Positives = 80/194 (41%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E T Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTAGSETTTA 1216 Query: 393 PAVGPLISTLQSEG 406 G +T + G Sbjct: 1217 STSGSETNTACTTG 1230 Score = 47.8 bits (112), Expect = 3e-05 Identities = 64/303 (21%), Positives = 111/303 (36%), Gaps = 19/303 (6%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSS----RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKAS 532 E ++ G ++ ++ST SS E+ T +G + +ST +L+ A+ Sbjct: 1209 AG--SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTAT 1266 Query: 533 KIS 535 ++ Sbjct: 1267 SLT 1269 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 42.0 bits (97), Expect = 0.002 Identities = 68/371 (18%), Positives = 137/371 (36%), Gaps = 29/371 (7%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST-----LQSEGYMSERDGSQKVSQPSAEV 424 +++ + + TTS +E T G +T L++ + G+ S +E Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 425 WNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKG 484 + + + + G + S+ S + +T + Sbjct: 1104 -----------------TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV 1146 Query: 485 YSNVRGKRHGSS--RKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLR 542 ++ V S+ +++T S+ E+ TT G + +ST + + + + Sbjct: 1147 FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206 Query: 543 ATPGSKTRVTS 553 +T GS+T S Sbjct: 1207 STAGSETTTAS 1217 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 52.4 bits (124), Expect = 1e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT--TSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.6 bits (122), Expect = 2e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.5 bits (114), Expect = 2e-05 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 + + + ++ST SS E+ T +G + +ST +L+ A+ ++ Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLT 1259 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216 Query: 393 PAVGPLISTLQSEG 406 G ST S G Sbjct: 1217 CTTGSETSTPSSAG 1230 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 46.6 bits (109), Expect = 7e-05 Identities = 52/214 (24%), Positives = 90/214 (42%), Gaps = 33/214 (15%) Query: 224 SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276 S T+++ AG E G + + T + + + ST + A+ T M T Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150 Query: 277 GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332 T V+ G+ + ++ A S ATT S + TTA AG+ G ++ S +G Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 333 A---------------ANISSEGISLALVGAAST-----SLEGTSTSMAGAASLSQDSSL 372 + ++ SE + ++G+ ST SLE T+TS+ G+ + + + Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITA 1270 Query: 373 SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404 S A A S T S T+ ++ P+ +T S Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304 Score = 41.2 bits (95), Expect = 0.003 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401 +++ + + TTS +E T G +T Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo sapiens] Length = 375 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 13/169 (7%) Query: 429 KERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNV 488 ++R ++K+R SR SH R R R+ + +K S RS K +R +E+ S Sbjct: 50 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE-RKKSRSRSRERKKSRS 108 Query: 489 RGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGS- 547 R + +S + S ++ RT ++++ S + +K+ K F RSL TP Sbjct: 109 RSRERKRRIRSRSRSRSRHRHRTR---SRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165 Query: 548 --KTRVTSHDREVDIV-----AKMVEKQNIEAKVEKAQGGQELEMISGT 589 + R T+ D + + AK +++Q + VEK Q QE+ + T Sbjct: 166 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEK-QKQQEIAAAAAT 213 Score = 40.0 bits (92), Expect = 0.006 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 6/116 (5%) Query: 437 RHPSRKSSHHRKAGESHRRRAGDKNQKASSHRS-ASGHKNTRDDKKEKGYSNVRGKRHGS 495 RH S+ S + E H DK + R + +N D K K + RG+ H Sbjct: 13 RHESKDKSSKKHKSEEH----NDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68 Query: 496 SR-KSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTR 550 SR + H S +E + ++ + + S + + ++K S+ S R R S++R Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 124 Score = 39.3 bits (90), Expect = 0.011 Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 10/142 (7%) Query: 427 ENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYS 486 + ++ K + H ++ S + + G+ K +S+ G ++R +E+ + Sbjct: 18 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 77 Query: 487 NVRGKRHGSSRKSSTHSSTKKESRT-TQELGKNQSASSTGALQKKASKISSFLRSLRATP 545 + R +KS + S +K+SR+ ++E K++S S + ++ S R Sbjct: 78 S----RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 133 Query: 546 GSKTRVTSHDREVDIVAKMVEK 567 S+TR S DR+ K +EK Sbjct: 134 RSRTRSRSRDRK-----KRIEK 150 Score = 33.1 bits (74), Expect = 0.76 Identities = 38/176 (21%), Positives = 64/176 (36%), Gaps = 29/176 (16%) Query: 426 NENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGY 485 + ++ R KK R SR+ R +RR +++ S HR TR + + Sbjct: 86 SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR-----HRTRSRSRTRSR 140 Query: 486 SNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATP 545 S R KR R+ S S + G+N + + AL ++ Sbjct: 141 SRDRKKRIEKPRRFS--RSLSRTPSPPPFRGRNTAMDAQEALARRL-------------- 184 Query: 546 GSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELE----MISGTMTSEKTEM 597 + + RE ++V K ++ E A GG L + SGT + + M Sbjct: 185 -ERAKKLQEQREKEMVEKQKQQ---EIAAAAATGGSVLNVAALLASGTQVTPQIAM 236 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 13/169 (7%) Query: 429 KERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNV 488 ++R ++K+R SR SH R R R+ + +K S RS K +R +E+ S Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE-RKKSRSRSRERKKSRS 167 Query: 489 RGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGS- 547 R + +S + S ++ RT ++++ S + +K+ K F RSL TP Sbjct: 168 RSRERKRRIRSRSRSRSRHRHRTR---SRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224 Query: 548 --KTRVTSHDREVDIV-----AKMVEKQNIEAKVEKAQGGQELEMISGT 589 + R T+ D + + AK +++Q + VEK Q QE+ + T Sbjct: 225 PFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEK-QKQQEIAAAAAT 272 Score = 44.3 bits (103), Expect = 3e-04 Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Query: 407 YMSERDGSQKVSQPSAEVWNENKERREKKD--RHPSRKSSHHRKAGESHRRRAGDKNQKA 464 Y R S++ + S +++ R K+ RH S+ S + E H DK + Sbjct: 40 YSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEH----NDKEHSS 95 Query: 465 SSHRS-ASGHKNTRDDKKEKGYSNVRGKRHGSSR-KSSTHSSTKKESRTTQELGKNQSAS 522 R + +N D K K + RG+ H SR + H S +E + ++ + + S Sbjct: 96 DKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKS 155 Query: 523 STGALQKKASKISSFLRSLRATPGSKTR 550 + + ++K S+ S R R S++R Sbjct: 156 RSRSRERKKSRSRSRERKRRIRSRSRSR 183 Score = 33.1 bits (74), Expect = 0.76 Identities = 38/176 (21%), Positives = 64/176 (36%), Gaps = 29/176 (16%) Query: 426 NENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGY 485 + ++ R KK R SR+ R +RR +++ S HR TR + + Sbjct: 145 SRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR-----HRTRSRSRTRSR 199 Query: 486 SNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATP 545 S R KR R+ S S + G+N + + AL ++ Sbjct: 200 SRDRKKRIEKPRRFS--RSLSRTPSPPPFRGRNTAMDAQEALARRL-------------- 243 Query: 546 GSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELE----MISGTMTSEKTEM 597 + + RE ++V K ++ E A GG L + SGT + + M Sbjct: 244 -ERAKKLQEQREKEMVEKQKQQ---EIAAAAATGGSVLNVAALLASGTQVTPQIAM 295 >gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo sapiens] Length = 1521 Score = 51.6 bits (122), Expect = 2e-06 Identities = 84/389 (21%), Positives = 140/389 (35%), Gaps = 27/389 (6%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TGL + + + A EG + + + + ST G+ E T G Sbjct: 487 SNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS-ENTTVSTTGSETTT 545 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 + TG T + TT + G TTA + A + + + Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 333 AANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAA 387 A+ SE S + G A++TS E T+ S G+ + + ++ S S T S+ Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 TEG + +T +E G+ VS +E + E S + S Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSE--TTITSTEGSEIT 723 Query: 448 KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKK 507 A + G + AS+ S + +T +G GS +++T S+T Sbjct: 724 TASIT-----GSETTTASTEGSETTTAST------EGSETTSASTTGS--ETTTASTTSS 770 Query: 508 ESRTTQELGKNQSASST-GALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVE 566 E+ +G + +ST G+ K S SS + ++ T S+T + S Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTV-FTENSETTIASTTASETTTVSTAG 829 Query: 567 KQNIEAKVEKAQGGQELEMISGTMTSEKT 595 + I A + G E + T SE T Sbjct: 830 SETIPA----STAGSETTTTTSTEGSETT 854 Score = 51.2 bits (121), Expect = 3e-06 Identities = 89/407 (21%), Positives = 151/407 (37%), Gaps = 52/407 (12%) Query: 222 DVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGG---AARTAGGMAVAGTATGP 278 +++A +++ + S T ++ S S +T + EG TAG TG Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + + TT ++ G TTA++ G ++ S G+ N + Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT-----GSEMTTVSTEGSENTTV 536 Query: 339 EGISLALVGAASTSLEGTSTSMAGA---------ASLSQDS-----SLSAAFAGSITTSK 384 ++T LE T+TS G+ A + DS + +A+ AGS TT+ Sbjct: 537 STTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTV 596 Query: 385 CAAERTEGPAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERREKKDRHPSRK 442 A+ A ST SE + GS+ S S+E + E E + Sbjct: 597 STADSENTTA-----STADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651 Query: 443 SSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 + S R + + ++ SA+G + T V + G++ S T Sbjct: 652 ETTMVSTTGSERTITSTEGSETTT-VSATGSETT-----------VSTEGSGTTTVSITG 699 Query: 503 SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S T K S T G + +ST + + I+ + +T GS+T S + A Sbjct: 700 SETTKVSTT----GSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSA 755 Query: 563 KMVEKQNIEAKVEKAQG------GQELEMISGTMTSEKTEMIVFETK 603 + A ++ G E M S T+ SE T++ +K Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMAS-TIGSETTKVSTASSK 801 Score = 48.9 bits (115), Expect = 1e-05 Identities = 92/363 (25%), Positives = 143/363 (39%), Gaps = 38/363 (10%) Query: 223 VSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTD- 281 +S+ T+ A A G AS + + +T A+E A TAG + TG +T Sbjct: 1 MSSETTVAPAAGSNTTTAS---TTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57 Query: 282 VAIAGAAMSPATGAMSIATT-KSAGPGQVTTALAGA--AIKNPGENESSKSMAGAAN--I 336 V+I+G+ ++ + A S TT SAG G T ++AG+ + G ++ S+ G + Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117 Query: 337 SSEGISLALVGAAS-----TSLEGTST---SMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 S+ G S TS G+ T S G+ + + ++ S A S T S+ Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177 Query: 389 RTEG-PAVGPLISTLQSEGYMSERDGSQ--KVSQPSAEVWNENKERRE--KKDRHPSRKS 443 T G + P ST SE GS+ VS +E + E S + Sbjct: 178 FTAGSETITP--STAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETT 235 Query: 444 SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK----KEKGYSNVRGKRHGS--SR 497 E+ AG + AS+ S + T D K G+ GS + Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTM 295 Query: 498 KSSTHSSTKKESRTTQELGKNQSASS-------TGALQKKASKISSFLRSLRATPGSKTR 550 S+ S T S E K +ASS G+ +AS + S ++ +T GS+T Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTV-STTGSETT 354 Query: 551 VTS 553 S Sbjct: 355 TAS 357 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 9/194 (4%) Query: 215 TGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGT 274 T +Y + TS+ EG + + T + + + ST + + G A T Sbjct: 1044 TAVYTTGSETTTTST-----EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 275 ATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 A T V I G+ + A+ S ATT S + TTA + S++ + Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTT-VS 1157 Query: 335 NISSEGISLALVG--AASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEG 392 I SE + + G A +TS EG+ T+ A A S+ ++ S A + + T S +E Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAG-SETTTASTAGSETTTASTSGSETNTA 1216 Query: 393 PAVGPLISTLQSEG 406 G ST S G Sbjct: 1217 CTTGSETSTPSSAG 1230 Score = 48.1 bits (113), Expect = 2e-05 Identities = 62/299 (20%), Positives = 108/299 (36%), Gaps = 21/299 (7%) Query: 244 TASAASPSTSTPGAA--EGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATT 301 TAS A T+T A E A G ++TG T + T TT Sbjct: 975 TASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETT 1034 Query: 302 KSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMA 361 G TTA + G ++ S G+ + A++ LE T+ S + Sbjct: 1035 TVTTAGSETTA-----VYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089 Query: 362 GAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVS--- 418 G+ + + ++ S IT SK TEG + +ST SE + GS+ + Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFT 1148 Query: 419 --QPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNT 476 + V E ++ + + AG + AS+ S + +T Sbjct: 1149 TVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAST 1208 Query: 477 RDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 + + + ++ST SS E+ T +G + +ST +L+ A+ ++ Sbjct: 1209 SGSETNTACT--------TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT 1259 Score = 47.0 bits (110), Expect = 5e-05 Identities = 44/196 (22%), Positives = 78/196 (39%), Gaps = 3/196 (1%) Query: 213 SETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVA 272 S TG + ++ + A G + T + + ST + +A Sbjct: 756 STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815 Query: 273 GTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAG 332 T T V+ AG+ PA+ A S TT ++ G TT + + + S Sbjct: 816 STTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTT 875 Query: 333 AANISSEGISLALVGA--ASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERT 390 A I SE + + G+ +TS EG+ T+ A S+ +++S + + T S +E T Sbjct: 876 ATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETT 934 Query: 391 EGPAVGPLISTLQSEG 406 G ++T+ + G Sbjct: 935 TASTEGSELTTVSTTG 950 Score = 45.4 bits (106), Expect = 1e-04 Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 33/214 (15%) Query: 224 SAATSSAYAGGE-------GIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTAT 276 S T+++ AG E G + + T + + + ST + A+ T M T Sbjct: 1091 SGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTV 1150 Query: 277 GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTA-LAGA---AIKNPGENESSKSMAG 332 T V+ G+ + ++ A S ATT S + TTA AG+ G ++ S +G Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 333 A---------------ANISSEGISLALVG-----AASTSLEGTSTSMAGAASLSQDSSL 372 + ++ SE + ++G A++ SLE T+TS+ G+ + + + Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270 Query: 373 SAAFAGSITTSKCAAERTEGP--AVGPLISTLQS 404 S A A S T S T+ ++ P+ +T S Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304 Score = 41.2 bits (95), Expect = 0.003 Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 5/212 (2%) Query: 193 APPEDNKSLVAAELHREGDQSET-GLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPS 251 A E +++ A + E + T G + + + A EG + + T + + + Sbjct: 866 ASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTT 925 Query: 252 TSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 ST G+ E A T G + TG T A + + M TT ++ G TT Sbjct: 926 ASTEGS-ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 ++ A + + ++ SE +++ G +T S EG+ T+ A S+ Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAG-SET 1043 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLIST 401 +++ + + TTS +E T G +T Sbjct: 1044 TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075 Score = 40.4 bits (93), Expect = 0.005 Identities = 73/383 (19%), Positives = 141/383 (36%), Gaps = 35/383 (9%) Query: 224 SAATSSAYAGGEGIQHASHGTASAASPSTSTPGAA-----EGGAARTAGGMAVAGTATGP 278 S T+++ G E + ++ G+ + S + S AA E A T + TG Sbjct: 222 SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGF 281 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISS 338 T A + M TT ++ G TT ++ A S + S Sbjct: 282 ETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA----------SSEVTTVFAAGS 331 Query: 339 EGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC-AAERTEGPAVGP 397 E I + VG+ +T++ T + A+ + ++S + TT+ +E T G Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGS 391 Query: 398 LISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRA 457 +T+ + G SE + E E ++ + + + Sbjct: 392 EATTVSTTG--SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTS 449 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGK 517 + AS+ S + T + + Y+ + +++T S+T E+ T +G Sbjct: 450 DSETTTASTEGSETTTVTTAGSETKTAYT--------TGSETTTASNTGLETTTVFTIGS 501 Query: 518 NQSASSTGALQKKASKISSFLRSLRATPGSK-TRVTSHDREVDIVAKMVEKQNIEAKVEK 576 + + +ST + A + + +T GS+ T V++ E V+ +E Sbjct: 502 DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS----TTGLETTTTS 557 Query: 577 AQGGQELEMISGT---MTSEKTE 596 + G E+ +S T T++ TE Sbjct: 558 TE-GSEMTTVSTTGAETTTDSTE 579 Score = 39.7 bits (91), Expect = 0.008 Identities = 69/360 (19%), Positives = 133/360 (36%), Gaps = 24/360 (6%) Query: 193 APPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPST 252 A +++ +A+ + E + T + VS A+S + + +A+ +T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTT 824 Query: 253 STPGAAEGGAARTAGGMAVAGTAT-GPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTT 311 + +E A TAG T+T G T A + + S TT + G TT Sbjct: 825 VSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETT 884 Query: 312 ALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAAST--SLEGTSTSMAGAASLSQD 369 + + + A+ SE +++ G+ +T S EG+ T+ A S+ Sbjct: 885 TASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEG-SEL 943 Query: 370 SSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENK 429 +++S + +IT S +E T ++T+ SE + GS+ + +A Sbjct: 944 TTVSTTGSETITVSAEGSETT-------TVTTMGSETTTASTAGSETTTVSTAGSETTTA 996 Query: 430 ERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVR 489 + S S + G + S+ S + T + Y+ Sbjct: 997 SIEGSETTTVSSTGSETTTVSTT-----GTETTITSTEGSETTTVTTAGSETTAVYT--- 1048 Query: 490 GKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKT 549 + +++T S+ E+ T G + +ST L+ S + +T GS+T Sbjct: 1049 -----TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 49.7 bits (117), Expect = 8e-06 Identities = 42/175 (24%), Positives = 81/175 (46%), Gaps = 2/175 (1%) Query: 214 ETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAG 273 ++G K D + A E +S G++S++S S+S+ EG G G Sbjct: 2537 DSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDG--G 2594 Query: 274 TATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGA 333 TG R A + A SPA+ + S +++ S+ +++ + ++ + + SS S + + Sbjct: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2654 Query: 334 ANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAE 388 ++ SS S + ++ST+ E +S S A+ + + SA A +K A + Sbjct: 2655 SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGK 2709 Score = 43.5 bits (101), Expect = 6e-04 Identities = 63/304 (20%), Positives = 113/304 (37%), Gaps = 39/304 (12%) Query: 245 ASAASPSTSTPGAAEGGAARTAG-GMAVAGTATGPRTDVAIA---GAAMSPATGAMSIAT 300 A ++ P P A +G A+ G G+ + D A A GA S ++ + Sbjct: 2508 AGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESS------S 2561 Query: 301 TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM 360 + S+G +++ + + + GE E K+ G S A AAS + +S+S Sbjct: 2562 SSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSS 2621 Query: 361 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420 + ++S S SS S++ + S ++S + S+ S S S S Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSS-------------SSSSSSSSSSSSSSSSSSSSS 2668 Query: 421 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480 S+ +E+ + P+ AG S + K K + S H + Sbjct: 2669 SSSTTDEDSSCSSDDEAAPA------PTAGPSAQAALPTKATKQAGKARPSAHSPGKKTP 2722 Query: 481 KEKGYSNVRGKRHGSSRKSSTHSSTKKESR------TTQELGKNQSASSTGALQKKASKI 534 + + K+ + ++ + R TT+EL K Q S + KI Sbjct: 2723 APQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSV----ENRPKI 2778 Query: 535 SSFL 538 ++FL Sbjct: 2779 AAFL 2782 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 48.5 bits (114), Expect = 2e-05 Identities = 74/332 (22%), Positives = 123/332 (37%), Gaps = 25/332 (7%) Query: 211 DQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMA 270 D G + + + ++S G + + HG+ S G + G Sbjct: 949 DSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTP 1008 Query: 271 VAGTATGPRTDVAIAGAAMSPAT--GAMSIATTKSAGPGQVTTALAGAAIKNPGENESSK 328 A T++G + + A SP G+ + S+ + A +A+++ G SS Sbjct: 1009 HAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSG 1068 Query: 329 SMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQD-SSLSAAFAGSITTSKCAA 387 S A + SE V + A S S S +F ++T Sbjct: 1069 SQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTH---- 1124 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHR 447 E++E ST + +G S + ++ S+ SA ++ R R R+ SHH Sbjct: 1125 EQSESAHGRTRTSTGRRQG--SHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHE 1182 Query: 448 KAGE------SHRRRAGDKNQKASSHR---SASGHKNTRDDKKEKGYSNVRGKRH---GS 495 ++ + SH + + +SH S S + TR DK+ S G RH S Sbjct: 1183 QSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAAS 1242 Query: 496 SRKSSTHSSTKKE----SRTTQELGKNQSASS 523 SS HS +E SRT++ G + S S Sbjct: 1243 WADSSRHSQVGQEQSSGSRTSRHQGSSVSQDS 1274 Score = 45.4 bits (106), Expect = 1e-04 Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 14/287 (4%) Query: 240 ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299 ASHG ++ +S + T A +TA A ++ G R +A S A Sbjct: 344 ASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSA---- 399 Query: 300 TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359 G GQ ++A++ + +++S S + N ++ +S G A + S Sbjct: 400 ----TGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGH--GKAGLRQQSHQES 453 Query: 360 MAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQ 419 G + S S+ + S +A G + G + + S R + + Q Sbjct: 454 TRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQ 513 Query: 420 PSAEVW-NENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRD 478 + ++ R+ S S H + SH G + S S + TR+ Sbjct: 514 DTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRN 573 Query: 479 DKKEKGYSNVRGKRH---GSSRKSSTHSSTKKESRTTQELGKNQSAS 522 +++ + G RH S SS HS + + +NQ +S Sbjct: 574 EEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSS 620 Score = 43.9 bits (102), Expect = 4e-04 Identities = 64/297 (21%), Positives = 108/297 (36%), Gaps = 27/297 (9%) Query: 240 ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299 A HG ++ +S + T + + A A ++ G R S Sbjct: 668 AGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERH---------GSRHQLQSAD 718 Query: 300 TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359 +++ +G G A +A+++ G SS S A + SE V + + Sbjct: 719 SSRHSGTGH---GQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSH 775 Query: 360 MAGAASLSQDSSL-SAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQ-KV 417 A S + S S +F ++T K +E + G GP Q + RD S+ Sbjct: 776 QESARDRSGERSRRSGSFLYQVSTHK-QSESSHG-WTGPSTGVRQGSHHEQARDNSRHSA 833 Query: 418 SQPSAEV--WNENKERREKKDRHPSRK--SSHHRKAGESHRRRAGDKNQKASSHRSASGH 473 SQ + + RR ++ H + S H + SH G + S S Sbjct: 834 SQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 893 Query: 474 KNTRDDKKEKGYSNVRGKRHGS-------SRKSSTHSSTKKESRTTQELGKNQSASS 523 + TR++++ + S G RH SR S + SRT++ G + S S Sbjct: 894 RTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDS 950 Score = 43.9 bits (102), Expect = 4e-04 Identities = 45/161 (27%), Positives = 67/161 (41%), Gaps = 33/161 (20%) Query: 403 QSEGYMSERDGSQKVSQPS--------AEVWNENKERR-----EKKDRHPSR--KSSHHR 447 QSEG R VSQ S +E W+ + R +++ RH SR +S H Sbjct: 3201 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHED 3260 Query: 448 KAGESH----RRRAGDKNQKASS-HRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 +AG H R++G ++ + SS ++AS H+ R E+ G RH S SS H Sbjct: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGER-----HGSRHQQSADSSRH 3315 Query: 503 --------SSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 SS ++SR G S S + + +S Sbjct: 3316 SGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVS 3356 Score = 43.5 bits (101), Expect = 6e-04 Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 25/130 (19%) Query: 403 QSEGYMSERDGSQKVSQPS--------AEVWNENKERR-----EKKDRHPSR--KSSHHR 447 QSEG + R VSQ S +E W+ + R +++ RH SR +S H Sbjct: 932 QSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHED 991 Query: 448 KAGESH----RRRAGDKNQKASS-HRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTH 502 +AG H R++G + + SS ++AS H+ R E+ G RH S SS H Sbjct: 992 RAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGER-----HGSRHQQSADSSRH 1046 Query: 503 SSTKKESRTT 512 S + ++ Sbjct: 1047 SGIPRRQASS 1056 Score = 43.1 bits (100), Expect = 7e-04 Identities = 52/190 (27%), Positives = 83/190 (43%), Gaps = 21/190 (11%) Query: 347 GAASTSLEGTSTSMAGAASLSQDSSL--SAAFAGSITTSKCAAERTEGPAVGPLISTLQS 404 G+ S S + +G S S +A++A S S+ E++ G + S Sbjct: 1212 GSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271 Query: 405 EGYMSER--DGSQKVSQPSAEVWNENKERREKKD--RHPS----RKSSHHRKAGESHRRR 456 + SER D S+++S SA + R + +D RHP ++SH A S R+ Sbjct: 1272 QDSDSERHSDDSERLSG-SASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSS--RQ 1328 Query: 457 AGDKNQKASSHRSA-SGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSST--KKESRTTQ 513 +G + ++SSH A S H+ R E+ G RH S SS HS ++ S + Sbjct: 1329 SGTHHTESSSHGQAVSSHEQARSSPGER-----HGSRHQQSADSSRHSGIGHRQASSAVR 1383 Query: 514 ELGKNQSASS 523 + G S+ S Sbjct: 1384 DSGHRGSSGS 1393 Score = 42.7 bits (99), Expect = 0.001 Identities = 89/415 (21%), Positives = 143/415 (34%), Gaps = 65/415 (15%) Query: 225 AATSSAYAGGEGIQHASHG-TASAASPSTSTPGAAEGG--------AARTAGGMAVAGTA 275 +A SS +G + +S G TAS+ + S+PG G + +A G A +A Sbjct: 349 SADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSA 408 Query: 276 TGPRTDVAIAGAAMSPATGAMSIATTKS-AGPGQVTTALAGAAIKNPGENESSKSMAGAA 334 R +G+ S + G + T+S +G G+ A ++ ES++ +G Sbjct: 409 VSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGK-------AGLRQQSHQESTRGRSGER 461 Query: 335 NISSEGISLALVGA-----ASTSLEGTSTSMAGAASLSQ--DSSLSAAFAGSITTSKCAA 387 + S G SL V ++ GTST + Q DSS +A T + Sbjct: 462 SGRS-GSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHP 520 Query: 388 ERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP------------SAEVWNENKERREKK 435 + G G + S S SQ SA N+E+ Sbjct: 521 GSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDG 580 Query: 436 DRHPSRK---------SSHHRKAGE---SHRRRAGDKNQKASSHRSASGHKNTRDDKKEK 483 RH + SS H + G+ S R + ++ S + GH + Sbjct: 581 TRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGS 640 Query: 484 GYSNVRGKRHGSSRKSSTH----------------SSTKKESRTTQELGKNQSASSTGAL 527 N G SR S H SS K +R TQ Q+ASS Sbjct: 641 ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQA 700 Query: 528 QKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQE 582 + A + L++ S+ T H + V + + ++ ++G E Sbjct: 701 RSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSE 755 Score = 42.7 bits (99), Expect = 0.001 Identities = 69/314 (21%), Positives = 114/314 (36%), Gaps = 23/314 (7%) Query: 230 AYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGM---AVAGTATGPRTDVAIAG 286 ++ +G AS G + + S S T + G G + A R + G Sbjct: 2169 SHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQG 2228 Query: 287 AAMSPAT----GAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGIS 342 + P T G+ + S G + + +G+A +N + +S G+ + S Sbjct: 2229 QSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED 2288 Query: 343 LALVGAASTSLEGTST-----SMAGAASLSQDSSLSAAFA--GSITTSKCAAERTEGPAV 395 A G ++ S + T S G A+ S + + S+A GS + R G Sbjct: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2348 Query: 396 GPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHR- 454 G S ++ G+ GS +E +E+ + + + H + ES R Sbjct: 2349 GQASSAVRDSGHR----GSSGSQASDSEGHSEDSDTQSVSAH--GQAGPHQQSHQESTRG 2402 Query: 455 RRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQE 514 R AG + S S H+ + G S G R GS K + SS S+ Q+ Sbjct: 2403 RSAGRSGRSGSFLYQVSTHEQSESAHGRTGTST--GGRQGSHHKQARDSSRHSTSQEGQD 2460 Query: 515 LGKNQSASSTGALQ 528 SS+G Q Sbjct: 2461 TIHGHPGSSSGGRQ 2474 Score = 42.4 bits (98), Expect = 0.001 Identities = 81/365 (22%), Positives = 132/365 (36%), Gaps = 47/365 (12%) Query: 225 AATSSAYAGGEGIQHASHGTA-SAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283 +A SS +G + +SHG A S+ + S+PG G + + A + +G A Sbjct: 1322 SADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQS---ADSSRHSGIGHRQA 1378 Query: 284 IAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESS-KSMAGAANISSEGIS 342 + S G+ T S G + + + +A G ++ S K A + S G S Sbjct: 1379 SSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRS 1438 Query: 343 LALVGAASTSLEGTSTSMAGAASL----------SQDSSLSAAFAGSITTSKCAAERTEG 392 + + S+ + ST A S +++SS +A T + + G Sbjct: 1439 RSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRG 1498 Query: 393 PAVGPL----ISTLQSEGY-------MSERDGSQKVSQP-SAEVWNENKERREKKDRHPS 440 G + GY D S S P SA N+E+ RH Sbjct: 1499 GRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSG 1558 Query: 441 RKSSHHR---KAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKR----- 492 S HH +AG S + G + + A S S + D+ +G+S +R Sbjct: 1559 --SRHHEPSTRAGSSRHSQVG-QGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615 Query: 493 ---HGSSRKSSTHSSTKKESRTTQELGKNQSASST------GALQKKASKISSFLRSLRA 543 +GS+R+ S H S S SA S+ A + +S R+ Sbjct: 1616 RNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARS 1675 Query: 544 TPGSK 548 +PG + Sbjct: 1676 SPGER 1680 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 17/162 (10%) Query: 409 SERDGSQKVSQPSAEVWNENKERREK------------KDRHPSRKSSHHRKAGESHRRR 456 S R GS +E +E+ ERR + + RH SR H++ SH Sbjct: 1587 SRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHS 1646 Query: 457 AGDKNQKASSHR--SASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSST--KKESRTT 512 A Q + H S+ G + ++ G RH S SST S T +++S Sbjct: 1647 AESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVV 1706 Query: 513 QELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSH 554 + G N+ +S + A + S +S+ A + SH Sbjct: 1707 GDSG-NRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSH 1747 Score = 39.7 bits (91), Expect = 0.008 Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 12/169 (7%) Query: 398 LISTLQSEGYMSERDGSQKVSQPS-AEVWNENKERREKKDRHPSRKSSHHRKAGESHRRR 456 L+ QS G + R VSQ S +E +E+ ERR S +HH A E + R Sbjct: 2224 LVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSG-----SASRNHHGSAQE--QSR 2276 Query: 457 AGDKNQKASSHRSASGHKNTRDDKKEKG---YSNVRGKRHGSSRKSSTHSSTKKESRTTQ 513 G ++ + S H +GH ++ + ++ G N G + SS + + S+ ++ Q Sbjct: 2277 DGSRHPR-SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQ 2335 Query: 514 ELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 + + S G Q ++ S R + S + S D + V+ Sbjct: 2336 QSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS 2384 Score = 38.1 bits (87), Expect = 0.024 Identities = 55/279 (19%), Positives = 107/279 (38%), Gaps = 22/279 (7%) Query: 240 ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299 A HG ++ +S + T + A A ++ G R +A S + Sbjct: 2614 AGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI--- 2670 Query: 300 TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359 G GQ ++A+ + + +++S + + + ++ +S G A + + S Sbjct: 2671 -----GHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH--GQAGSHQQSHQES 2723 Query: 360 MAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQ-KVS 418 G + + S S +F ++T + +E + G GP Q + +D S+ S Sbjct: 2724 ARGRSG--ETSGHSGSFLYQVSTHE-QSESSHG-WTGPSTRGRQGSRHEQAQDSSRHSAS 2779 Query: 419 QPSAEVWN----ENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHK 474 Q + ++ R+ S SS H + SH G + S S + Sbjct: 2780 QDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASR 2839 Query: 475 NTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQ 513 TR++++ S G RH ++STH+ + S+ Q Sbjct: 2840 TTRNEEQSGDGSRHSGSRH---HEASTHADISRHSQAVQ 2875 Score = 38.1 bits (87), Expect = 0.024 Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 23/127 (18%) Query: 391 EGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKD---------RHPSR 441 +G + GP T +++G +D + +E W+ + R + RHP+ Sbjct: 3523 QGQSAGP--RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPT- 3579 Query: 442 KSSHHRKAGESH----RRRAGDKN-QKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSS 496 S H +AG H R++G + + +S ++AS H+ R E+ G H S Sbjct: 3580 -SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGER-----HGSHHQQS 3633 Query: 497 RKSSTHS 503 SS HS Sbjct: 3634 ADSSRHS 3640 Score = 37.4 bits (85), Expect = 0.040 Identities = 35/114 (30%), Positives = 50/114 (43%), Gaps = 25/114 (21%) Query: 438 HPSRKSSHH--------------RKAGESHRRRAGDKNQK--ASSHRSASG--HKNTRDD 479 H RK SHH RK S RR K K + S R G H+++ + Sbjct: 99 HKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEK 158 Query: 480 KKEKGYSNV-RGKRHGSSRKSSTHSSTKKESRTTQ--ELGKNQSASSTGALQKK 530 K+ KGYS R + +G + H+S+KKE T+ LG N+ S +K+ Sbjct: 159 KERKGYSPTHREEEYGKNH----HNSSKKEKNKTENTRLGDNRKRLSERLEEKE 208 Score = 37.4 bits (85), Expect = 0.040 Identities = 65/300 (21%), Positives = 102/300 (34%), Gaps = 34/300 (11%) Query: 240 ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299 A HG ++ +S + T A + A A ++ G R +A S + Sbjct: 2290 AGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI--- 2346 Query: 300 TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGI---SLALVGAASTSLEGT 356 G GQ A +A+++ G SS S A + SE S++ G A + Sbjct: 2347 -----GHGQ-----ASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSH 2396 Query: 357 STSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQK 416 S G ++ S S + S +A G + G + + S R + + Sbjct: 2397 QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQ 2456 Query: 417 VSQ------PSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSA 470 Q P + E+ SHH SH G + S Sbjct: 2457 EGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHH-----SHTTSQGRSDASHGHSGSR 2511 Query: 471 SGHKNTRDDKKEKGYSNVRGKRH---GSSRKSSTHSST----KKESRTTQELGKNQSASS 523 S + TR+D++ S G RH S SS HS + RT++ G + S S Sbjct: 2512 SASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDS 2571 Score = 37.4 bits (85), Expect = 0.040 Identities = 79/377 (20%), Positives = 126/377 (33%), Gaps = 35/377 (9%) Query: 190 SGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAAS 249 SG E++ AA H + S + +A SS ++G HG AS+A Sbjct: 3598 SGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG------IGHGQASSAV 3651 Query: 250 PSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQV 309 + G++ A+ + G + T + V+ G A +SAG Sbjct: 3652 RDSGHRGSSGSQASDSEGHSEDSDTQS-----VSAHGQAGPHQQSHQESTRGRSAG---- 3702 Query: 310 TTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQD 369 + +G+ + +E S+S G A S+ G S + +S A+ QD Sbjct: 3703 RSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQ------GSRHEQARDSSRHSASQEGQD 3756 Query: 370 SSLS--AAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNE 427 + + G S G S S+G G S E NE Sbjct: 3757 TIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNE 3816 Query: 428 NKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSN 487 E+ RH + +S R + + A S RS + D + Y Sbjct: 3817 --EQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPE 3874 Query: 488 VRGKR--------HGSSRKSSTHSSTKKES--RTTQELGKNQSASSTGALQKKASKISSF 537 +R HGSSR+ S S S R T ++ S + K+ SS Sbjct: 3875 DSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSL 3934 Query: 538 LRSLRATPGSKTRVTSH 554 + G ++R + H Sbjct: 3935 SQDSAYHSGIQSRGSPH 3951 Score = 37.0 bits (84), Expect = 0.052 Identities = 70/305 (22%), Positives = 109/305 (35%), Gaps = 49/305 (16%) Query: 304 AGPGQVTTALAGAAIKNPGENESSKSMAGAAN--ISSEGISLALVGAASTSLEGTSTSMA 361 A GQ + A +N ++ +G+ + SS A EG+ TS Sbjct: 882 ASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRR 941 Query: 362 GAASLSQDSSL------SAAFAGSITTSK--CAAERTEGPAVGPLISTLQSEGYMSERDG 413 +S+SQDS S ++GS + + A E++ + P G+ D Sbjct: 942 QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADS 1001 Query: 414 SQKVSQPSAE-------VWNENKERREKKDRHPSR-----KSSHH----RKAGESHRRRA 457 S++ P AE + + R +RH SR SS H R+ S R + Sbjct: 1002 SRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDS 1061 Query: 458 GDKNQKASSHRSASGHKNTRDDKKEKG-----------------YSNVRGKRHGS-SRKS 499 G S + GH D + G +S R R GS + Sbjct: 1062 GHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQV 1121 Query: 500 STH-SSTKKESRTTQELGKNQSASSTGALQKKASKISSFLR-SLRATPGSK---TRVTSH 554 STH S RT G+ Q + A S + ++RA PGS+ + + H Sbjct: 1122 STHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHH 1181 Query: 555 DREVD 559 ++ VD Sbjct: 1182 EQSVD 1186 Score = 36.6 bits (83), Expect = 0.069 Identities = 81/381 (21%), Positives = 136/381 (35%), Gaps = 71/381 (18%) Query: 225 AATSSAYAGGEGIQHASHG-TASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283 +A SS +G + +S G AS+ + S+PG G + + + + TG R D + Sbjct: 1646 SAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSST-DSGTGRRQDSS 1704 Query: 284 IAGAA---------------MSPATGAMSIATTKSAGPGQVT------------TALAGA 316 + G + S + S++ AGP Q + + +G+ Sbjct: 1705 VVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGS 1764 Query: 317 AIKNPGENESSKSMAGAANISSEGISLALVGAA------STSLEGTST-------SMAGA 363 + +E S+S G S+ G + A S S EG T S G Sbjct: 1765 FLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGR 1824 Query: 364 ASLSQDSSL-SAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSA 422 + S+ S+ +GS + + ER++ +S QS GS+ VS+ + Sbjct: 1825 QGSHYEQSVDSSGHSGSHHSHTTSQERSD-------VSRGQS--------GSRSVSRQTR 1869 Query: 423 EVWNENKERREKKDRHPSRKS----SHHRKAGE---SHRRRAGDKNQKASSHRSASGHKN 475 R RH S S H + G+ S R + ++ S + GH Sbjct: 1870 NEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSE 1929 Query: 476 TRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKIS 535 + N G SR S H + E R G SA S+ + ++ S Sbjct: 1930 DSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRA----GHGHSADSSRQSGTRHTESS 1985 Query: 536 SFLRSLRATPGSKTRVTSHDR 556 S R A+ + R ++ +R Sbjct: 1986 S--RGQAASSHEQARSSAGER 2004 Score = 36.6 bits (83), Expect = 0.069 Identities = 56/283 (19%), Positives = 109/283 (38%), Gaps = 30/283 (10%) Query: 240 ASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIA 299 A HG ++ +S + T + A A ++ G R +A S + Sbjct: 2938 AGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI--- 2994 Query: 300 TTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTS 359 G GQ ++A+ + + +++S + + + ++ +S G A + + S Sbjct: 2995 -----GHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH--GQAGSHQQSHQES 3047 Query: 360 MAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQ 419 G + + S S +F ++T + +E + G GP ST +G S + +Q S+ Sbjct: 3048 ARGRSG--ETSGHSGSFLYQVSTHE-QSESSHG-WTGP--STRGRQG--SRHEQAQDSSR 3099 Query: 420 PSAEVWNENKERREKKDRHPSRKSSHHRK---------AGESHRRRAGDKNQKASSHRSA 470 SA + ++ R R+ HH + SH G + S Sbjct: 3100 HSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR 3159 Query: 471 SGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQ 513 S + TR++++ S RH ++STH+ + S+ Q Sbjct: 3160 SASRTTRNEEQSGDSSRHSVSRH---HEASTHADISRHSQAVQ 3199 Score = 36.6 bits (83), Expect = 0.069 Identities = 34/163 (20%), Positives = 63/163 (38%), Gaps = 10/163 (6%) Query: 403 QSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQ 462 QS G + R+ VSQ S +++ E +R S +HR G + + Sbjct: 3525 QSAGPRTSRNQGSSVSQDS-----DSQGHSEDSERWSGSASRNHR--GSAQEQSRDGSRH 3577 Query: 463 KASSHRSASGHKNTRDDKKEKG---YSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQ 519 S H +GH ++ + ++ G N G + SS + + S+ ++ Q+ + Sbjct: 3578 PTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS 3637 Query: 520 SASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S G Q ++ S R + S + S D + V+ Sbjct: 3638 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS 3680 Score = 36.2 bits (82), Expect = 0.089 Identities = 29/122 (23%), Positives = 47/122 (38%), Gaps = 10/122 (8%) Query: 409 SERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHR 468 S R GS +E + E+ ERR + S +HH G S + SSHR Sbjct: 3856 SRRQGSSVSQDSDSEAYPEDSERRSE-----SASRNHH---GSSREQSRDGSRHPGSSHR 3907 Query: 469 SASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQ 528 + H + + + + G S+ S+ HS +SR + + S G + Sbjct: 3908 DTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGI--QSRGSPHSSSSYHYQSEGTER 3965 Query: 529 KK 530 +K Sbjct: 3966 QK 3967 Score = 35.0 bits (79), Expect = 0.20 Identities = 35/123 (28%), Positives = 51/123 (41%), Gaps = 29/123 (23%) Query: 403 QSEGYMSERDGSQKVSQPS--------AEVWNEN---------KERREKKDRHPSRKSSH 445 QSEG R VSQ S +E W+ + +E+ RHP +S Sbjct: 2877 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP--RSHQ 2934 Query: 446 HRKAGESH----RRRAGDKN-QKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSS 500 +AG H R++G ++ Q +S ++AS H+ R E+ G H S SS Sbjct: 2935 EDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGER-----HGSHHQQSADSS 2989 Query: 501 THS 503 HS Sbjct: 2990 RHS 2992 Score = 33.9 bits (76), Expect = 0.44 Identities = 64/344 (18%), Positives = 118/344 (34%), Gaps = 31/344 (9%) Query: 190 SGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAG------GEGIQHASHG 243 SG E + AA H + S + +A SS ++G ++ + H Sbjct: 3274 SGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHW 3333 Query: 244 TASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA---IAGAAMSPATGAMSIAT 300 S+ S ++ + G +E ++ G AG + A G + + ++T Sbjct: 3334 -GSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVST 3392 Query: 301 TKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSM 360 + + T + + ++ S +A+ + G++ +G+ Sbjct: 3393 HEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQ 3452 Query: 361 AGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQP 420 S D S + S TTS+ ++ + G + G ++ Q+ DGS+ Sbjct: 3453 ------SVDRSGHSGSHHSHTTSQGRSDASRGQS-GSRSASRQTRNDEQSGDGSR----- 3500 Query: 421 SAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDK 480 W+ + E + D +S + AG R G S + GH + Sbjct: 3501 --HSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSS---VSQDSDSQGHSEDSERW 3555 Query: 481 KEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASST 524 N RG SR S H ++ E R G SA S+ Sbjct: 3556 SGSASRNHRGSAQEQSRDGSRHPTSHHEDRA----GHGHSAESS 3595 Score = 33.1 bits (74), Expect = 0.76 Identities = 33/164 (20%), Positives = 62/164 (37%), Gaps = 11/164 (6%) Query: 403 QSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQ 462 QS G + R+ VSQ S +++ E +R S +H G + + Sbjct: 1904 QSSGPRTSRNQGSSVSQDS-----DSQGHSEDSERWSGSASRNH--LGSAWEQSRDGSRH 1956 Query: 463 KASSHRSASGHKNTRDDKKEKG----YSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKN 518 S H +GH ++ D ++ G S+ RG+ S ++ + + + S + + Sbjct: 1957 PGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADS 2016 Query: 519 QSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVA 562 S G Q ++ S R + S + S D + V+ Sbjct: 2017 SRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVS 2060 Score = 33.1 bits (74), Expect = 0.76 Identities = 66/293 (22%), Positives = 109/293 (37%), Gaps = 44/293 (15%) Query: 225 AATSSAYA-GGEGIQHASHGTASAASPSTSTPGAAEGGAA-RTAGGMAVAGTAT----GP 278 AA+S A G +H SH SA S S G + +A R +G +G+ G Sbjct: 2639 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGH 2698 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSA-GPGQVTTALAGAAIKNPGENESSKSMAGAANIS 337 D + G+ + +SA G T+ +G+ + +E S+S G S Sbjct: 2699 SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 2758 Query: 338 SEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGP 397 + G +G+ A QDSS +A T + + G G Sbjct: 2759 TRG------------RQGSRHEQA------QDSSRHSASQDGQDTIRGHPGSSRGGRQGY 2800 Query: 398 LIS-TLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRR 456 ++ S G+ S SQ ++ R + R SR + + ++G+ R Sbjct: 2801 HHEHSVDSSGHSGSHH-SHTTSQGRSDA-----SRGQSGSRSASRTTRNEEQSGDGSRH- 2853 Query: 457 AGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKES 509 +G ++ +AS+H S H V+G+ GS R SS ++S Sbjct: 2854 SGSRHHEASTHADISRHSQA-----------VQGQSEGSRRSRRQGSSVSQDS 2895 Score = 32.3 bits (72), Expect = 1.3 Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 14/141 (9%) Query: 355 GTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGS 414 G+ S +S+SQDS A S S+ A+ G S QS RDGS Sbjct: 3852 GSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGS------SREQS------RDGS 3899 Query: 415 QKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHK 474 + + + + + D +++ H + +G ++ + S H S+S H Sbjct: 3900 RHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQS-RGSPHSSSSYHY 3958 Query: 475 NTRDDKKEKGYSNVRGKRHGS 495 + +++KG S + RHGS Sbjct: 3959 QSEGTERQKGQSGLVW-RHGS 3978 Score = 31.6 bits (70), Expect = 2.2 Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 13/170 (7%) Query: 367 SQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEV-- 424 S D S + S TTS+ ++ + G + G ++ Q+ DGS+ E Sbjct: 1184 SVDRSGHSGSHHSHTTSQGRSDASHGQS-GSRSASRQTRKDKQSGDGSRHSGSRHHEAAS 1242 Query: 425 WNENKERREK-KDRHPSRKSSHHRKAG---ESHRRRAGDKNQKASSHRSASGH----KNT 476 W ++ + +++ ++S H+ + +S R D +++ S S + H + + Sbjct: 1243 WADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQS 1302 Query: 477 RDDKKEKGYSNVRGKRHGSSRKSSTHSST--KKESRTTQELGKNQSASST 524 RD + G+ HG S SS S T + S Q + ++ A S+ Sbjct: 1303 RDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSS 1352 Score = 31.2 bits (69), Expect = 2.9 Identities = 41/171 (23%), Positives = 71/171 (41%), Gaps = 19/171 (11%) Query: 381 TTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS 440 ++S+ R E + PL E +R GS +VSQ +++ E +RH Sbjct: 267 SSSQVNRSRHENTSQVPL-----QESRTRKRRGS-RVSQD-----RDSEGHSEDSERHSG 315 Query: 441 RKS-SHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKS 499 S +HH A E + R G ++ ++ AS H ++ D ++ G + G + + Sbjct: 316 SASRNHHGSAWE--QSRDGSRHPRSHDEDRAS-HGHSADSSRQSGTRHAETSSRGQT--A 370 Query: 500 STHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFL--RSLRATPGSK 548 S+H + G QSA S+ + SS + R R + GS+ Sbjct: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421 Score = 31.2 bits (69), Expect = 2.9 Identities = 72/330 (21%), Positives = 123/330 (37%), Gaps = 50/330 (15%) Query: 225 AATSSAYA-GGEGIQHASHGTASAASPSTSTPGAAEGGAA-RTAGGMAVAGTAT----GP 278 AA+S A G +H SH SA S S G + +A R +G +G+ G Sbjct: 2963 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGH 3022 Query: 279 RTDVAIAGAAMSPATGAMSIATTKSA-GPGQVTTALAGAAIKNPGENESSKSMAGAANIS 337 D + G+ + +SA G T+ +G+ + +E S+S G S Sbjct: 3023 SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 3082 Query: 338 SEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGP 397 + G +G+ A QDSS +A T + + G G Sbjct: 3083 TRG------------RQGSRHEQA------QDSSRHSASQYGQDTIRGHPGSSRGGRQGY 3124 Query: 398 LIS-TLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRR 456 ++ S G+ S SQ ++ R + R SR + + ++G+S R Sbjct: 3125 HHEHSVDSSGHSGSHH-SHTTSQGRSDA-----SRGQSGSRSASRTTRNEEQSGDSSRHS 3178 Query: 457 AGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE------SR 510 ++ +AS+H S H V+G+ GS R SS ++ S Sbjct: 3179 VS-RHHEASTHADISRHSQA-----------VQGQSEGSRRSRRQGSSVSQDSDSEGHSE 3226 Query: 511 TTQELGKNQSASSTGALQKKASKISSFLRS 540 ++ + S + G++Q+++ S RS Sbjct: 3227 DSERWSGSASRNHRGSVQEQSRHGSRHPRS 3256 Score = 30.4 bits (67), Expect = 4.9 Identities = 34/161 (21%), Positives = 60/161 (37%), Gaps = 18/161 (11%) Query: 401 TLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDK 460 +L E + ER S + S++V N+ R E + P ++S ++ G Sbjct: 249 SLLEENKIYERSRSSD-GKSSSQV---NRSRHENTSQVPLQESRTRKRRGS--------- 295 Query: 461 NQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQS 520 + S R + GH + N G SR S H + E R + + S Sbjct: 296 --RVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSS 353 Query: 521 ASSTGALQKKASK--ISSFLRSLRATPGSKTRVTSHDREVD 559 S + +S+ +S R++PG + + H + D Sbjct: 354 RQSGTRHAETSSRGQTASSHEQARSSPGER-HGSGHQQSAD 393 Score = 29.6 bits (65), Expect = 8.4 Identities = 67/330 (20%), Positives = 105/330 (31%), Gaps = 50/330 (15%) Query: 225 AATSSAYA-GGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVA 283 AA+S A G +H SH +A S + G G A+ G + +D Sbjct: 1990 AASSHEQARSSAGERHGSHHQLQSADSSRHS-GIGHGQASSAVRDSGHRGYSGSQASD-- 2046 Query: 284 IAGAAMSPATGAMSIATTKSAGPGQVT------------TALAGAAIKNPGENESSKSMA 331 S + S++ AGP Q + + +G+ + +E S+S Sbjct: 2047 --SEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTH 2104 Query: 332 GAANISSEGISLALVGAA------STSLEGTST-------SMAGAASLSQDSSLS-AAFA 377 G + S+ G + A S S EG T S G Q+ S+ + + Sbjct: 2105 GQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHS 2164 Query: 378 GSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDR 437 GS + + R++ S G R S+K + Sbjct: 2165 GSHHSHTTSQGRSDA-----------SRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEA 2213 Query: 438 HPSRKSSHHRKAGE---SHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHG 494 SS H G+ S R + + S + GH + + N G Sbjct: 2214 SSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQE 2273 Query: 495 SSRKSSTHSSTKKESRTTQELGKNQSASST 524 SR S H + E R G SA S+ Sbjct: 2274 QSRDGSRHPRSHHEDRA----GHGHSAESS 2299 >gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] Length = 1512 Score = 48.5 bits (114), Expect = 2e-05 Identities = 66/265 (24%), Positives = 100/265 (37%), Gaps = 32/265 (12%) Query: 278 PRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKS-MAGAANI 336 P +A G A + A A + ++ S GP LA + G + + AG Sbjct: 57 PLLFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAE 116 Query: 337 SSEGISLALV---GAASTSLEGTSTSMAGAASLSQDSSLSAAFAG-SITTSKCAAERTEG 392 SL G S G T + +S S G S T+ AA T G Sbjct: 117 KRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGG 176 Query: 393 PAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS--RKSSHHRKAG 450 P S+ G+Q+ E ERR ++DR S R HR+ Sbjct: 177 SGGSPASSS-----------GTQRRG--------EGSERRPRRDRRSSSGRSKERHRE-- 215 Query: 451 ESHRRRAGDK-NQKASSHRSASGHK-NTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE 508 HRRR G + +AS RS H R + + G S+ G R S+ +S+ SS++K+ Sbjct: 216 --HRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKD 273 Query: 509 SRTTQELGKNQSASSTGALQKKASK 533 + + +S+ + K+ K Sbjct: 274 RDSKAHRSRTKSSKEPPSAYKEPPK 298 Score = 40.0 bits (92), Expect = 0.006 Identities = 88/396 (22%), Positives = 145/396 (36%), Gaps = 44/396 (11%) Query: 212 QSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAAR------T 265 QSE GL SAAT++ AGG G G+ + + S+ T EG R + Sbjct: 152 QSEQGLLLG-GASAATAATAAGGTG------GSGGSPASSSGTQRRGEGSERRPRRDRRS 204 Query: 266 AGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENE 325 + G + R D G+ S + S +G + A +G++ + G + Sbjct: 205 SSGRSKERHREHRRRDGQRGGSEASKSRSRHS-----HSGEERAEVAKSGSSSSSGGRRK 259 Query: 326 SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC 385 S+ + + +++ + S A +S E S + +D + A+ + S Sbjct: 260 SASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPL 319 Query: 386 AAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSH 445 R + P +L+S S G S S + ++ SR SS+ Sbjct: 320 GG-RDDSPVSHRASQSLRSRKSPSPAGGGS--SPYSRRLPRSPSPYSRRRSPSYSRHSSY 376 Query: 446 HRKAGESHRRRAGDKNQKASSHRSA----SGHKNTRDDKKEKGYSNVRGKRHGSSRKSST 501 R S + +++ S S SG +R + +S R RH SR S Sbjct: 377 ERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSR-HSRSRS-RHRLSRSRSR 434 Query: 502 HSSTKKESRTTQ-----ELGKNQSASSTGALQK-KASKISSFLRSLRA-----------T 544 HSS + T + EL KN+ A + A + +A+K + ++ A T Sbjct: 435 HSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTST 494 Query: 545 PGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGG 580 P TS K V+K IE + GG Sbjct: 495 PTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGG 530 >gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] Length = 1452 Score = 48.5 bits (114), Expect = 2e-05 Identities = 66/265 (24%), Positives = 100/265 (37%), Gaps = 32/265 (12%) Query: 278 PRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKS-MAGAANI 336 P +A G A + A A + ++ S GP LA + G + + AG Sbjct: 57 PLLFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAE 116 Query: 337 SSEGISLALV---GAASTSLEGTSTSMAGAASLSQDSSLSAAFAG-SITTSKCAAERTEG 392 SL G S G T + +S S G S T+ AA T G Sbjct: 117 KRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGG 176 Query: 393 PAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPS--RKSSHHRKAG 450 P S+ G+Q+ E ERR ++DR S R HR+ Sbjct: 177 SGGSPASSS-----------GTQRRG--------EGSERRPRRDRRSSSGRSKERHRE-- 215 Query: 451 ESHRRRAGDK-NQKASSHRSASGHK-NTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKE 508 HRRR G + +AS RS H R + + G S+ G R S+ +S+ SS++K+ Sbjct: 216 --HRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKD 273 Query: 509 SRTTQELGKNQSASSTGALQKKASK 533 + + +S+ + K+ K Sbjct: 274 RDSKAHRSRTKSSKEPPSAYKEPPK 298 Score = 40.0 bits (92), Expect = 0.006 Identities = 88/396 (22%), Positives = 145/396 (36%), Gaps = 44/396 (11%) Query: 212 QSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAAR------T 265 QSE GL SAAT++ AGG G G+ + + S+ T EG R + Sbjct: 152 QSEQGLLLG-GASAATAATAAGGTG------GSGGSPASSSGTQRRGEGSERRPRRDRRS 204 Query: 266 AGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENE 325 + G + R D G+ S + S +G + A +G++ + G + Sbjct: 205 SSGRSKERHREHRRRDGQRGGSEASKSRSRHS-----HSGEERAEVAKSGSSSSSGGRRK 259 Query: 326 SSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKC 385 S+ + + +++ + S A +S E S + +D + A+ + S Sbjct: 260 SASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRRSLSPL 319 Query: 386 AAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSH 445 R + P +L+S S G S S + ++ SR SS+ Sbjct: 320 GG-RDDSPVSHRASQSLRSRKSPSPAGGGS--SPYSRRLPRSPSPYSRRRSPSYSRHSSY 376 Query: 446 HRKAGESHRRRAGDKNQKASSHRSA----SGHKNTRDDKKEKGYSNVRGKRHGSSRKSST 501 R S + +++ S S SG +R + +S R RH SR S Sbjct: 377 ERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSR-HSRSRS-RHRLSRSRSR 434 Query: 502 HSSTKKESRTTQ-----ELGKNQSASSTGALQK-KASKISSFLRSLRA-----------T 544 HSS + T + EL KN+ A + A + +A+K + ++ A T Sbjct: 435 HSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTST 494 Query: 545 PGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGG 580 P TS K V+K IE + GG Sbjct: 495 PTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGG 530 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.123 0.341 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,040,399 Number of Sequences: 37866 Number of extensions: 978744 Number of successful extensions: 8224 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 177 Number of HSP's successfully gapped in prelim test: 483 Number of HSP's that attempted gapping in prelim test: 5255 Number of HSP's gapped (non-prelim): 2164 length of query: 605 length of database: 18,247,518 effective HSP length: 108 effective length of query: 497 effective length of database: 14,157,990 effective search space: 7036521030 effective search space used: 7036521030 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.