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Search of human proteins with 222136684
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222136684 prickle homolog 1 [Homo sapiens]
(831 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222136684 prickle homolog 1 [Homo sapiens] 1731 0.0
gi|222136682 prickle homolog 1 [Homo sapiens] 1731 0.0
gi|222136680 prickle homolog 1 [Homo sapiens] 1731 0.0
gi|222136678 prickle homolog 1 [Homo sapiens] 1731 0.0
gi|38524620 prickle-like 2 [Homo sapiens] 766 0.0
gi|7710129 LIM domain only 6 [Homo sapiens] 484 e-136
gi|7661666 testin isoform 1 [Homo sapiens] 252 1e-66
gi|23238188 testin isoform 2 [Homo sapiens] 252 1e-66
gi|118722347 over-expressed breast tumor protein [Homo sapiens] 222 1e-57
gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens] 173 5e-43
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 103 7e-22
gi|109638745 transforming growth factor beta 1 induced transcrip... 98 3e-20
gi|21361591 transforming growth factor beta 1 induced transcript... 98 3e-20
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 96 1e-19
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 96 1e-19
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 95 2e-19
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 95 2e-19
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 95 2e-19
gi|170932518 paxillin isoform 3 [Homo sapiens] 95 2e-19
gi|170932516 paxillin isoform 2 [Homo sapiens] 95 2e-19
gi|170932514 paxillin isoform 1 [Homo sapiens] 95 2e-19
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 95 2e-19
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 95 2e-19
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 95 2e-19
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 94 7e-19
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 94 7e-19
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 94 7e-19
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 94 7e-19
gi|30410801 activator of cAMP-responsive element modulator (CREM... 90 8e-18
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 86 1e-16
>gi|222136684 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 1731 bits (4483), Expect = 0.0
Identities = 831/831 (100%), Positives = 831/831 (100%)
Query: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
Query: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
Query: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
Sbjct: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
Query: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
Sbjct: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
Query: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
Sbjct: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
Query: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
Sbjct: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
Query: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
Sbjct: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
Query: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS
Sbjct: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
>gi|222136682 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 1731 bits (4483), Expect = 0.0
Identities = 831/831 (100%), Positives = 831/831 (100%)
Query: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
Query: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
Query: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
Sbjct: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
Query: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
Sbjct: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
Query: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
Sbjct: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
Query: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
Sbjct: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
Query: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
Sbjct: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
Query: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS
Sbjct: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
>gi|222136680 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 1731 bits (4483), Expect = 0.0
Identities = 831/831 (100%), Positives = 831/831 (100%)
Query: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
Query: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
Query: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
Sbjct: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
Query: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
Sbjct: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
Query: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
Sbjct: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
Query: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
Sbjct: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
Query: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
Sbjct: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
Query: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS
Sbjct: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
>gi|222136678 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 1731 bits (4483), Expect = 0.0
Identities = 831/831 (100%), Positives = 831/831 (100%)
Query: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
Sbjct: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
Query: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
Sbjct: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
Query: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
Query: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
Sbjct: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
Query: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
Sbjct: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
Query: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
Sbjct: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
Query: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
Sbjct: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
Query: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
Sbjct: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
Query: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS
Sbjct: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
>gi|38524620 prickle-like 2 [Homo sapiens]
Length = 844
Score = 766 bits (1979), Expect = 0.0
Identities = 429/851 (50%), Positives = 542/851 (63%), Gaps = 31/851 (3%)
Query: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
MPLEME +SKL F QR+STSDDDSGCALEEYAWVPPGL+PEQ+ Y++CLPEEKVPYV
Sbjct: 5 MPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYV 64
Query: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
NSPGEK RIKQLL+QLPPHDNEVRYC SL EEEK+EL++FS+QRK+E LGRG ++
Sbjct: 65 NSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVT 124
Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
+ A+CEQCG +INGG++AVFASRAG GVCWHP CFVC CNELLVDLIYFYQDGKI+CG
Sbjct: 125 MTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RHHAE LKPRC+ACDEIIFADECTEAEGRHWHMKHFCC ECETVLGGQRYIMK+GRP+CC
Sbjct: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244
Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
CFESLYAEYC+TC +HIG+D QMTYDGQHWHATE CF CA CK SLLG PFLPKQGQI
Sbjct: 245 HCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQI 304
Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
+CS+ CS GED + SDSSDSAFQ+AR+++SRRS ++GK+ ++ L L
Sbjct: 305 FCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEE--PMLNQHSQLQVSS 362
Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
LS + D LS ++D LSLS Q S + W+ R E + E + + QLL
Sbjct: 363 NRLSADV-DPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPL-QLLS 420
Query: 421 KFGDKSLFQPQPNEMDIRASEHWIS--DNMVKSKTELKQNNQSLASKKYQSDMY-----W 473
+ ++ + P + E W N +S + + K+ + D Y
Sbjct: 421 QCNIRTSYSPGGQGAGAQ-PEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRS 479
Query: 474 AQSQDGLGDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKP-EQS 532
+S + ++ G + +E E + G T+ SL+ D+ P EQ+
Sbjct: 480 QESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQT 539
Query: 533 VRDSMDSLALSNITGASVDG-----ENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSM 587
R SM+SLALSN TG S DG E+ R S+ L M EK+SNMGTLNSSM
Sbjct: 540 PRGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVS--EKLSNMGTLNSSM 597
Query: 588 LHRSAESLKSLSSELCPEKILPEEKPVHLPV-LRRSKSQSRPQQVKFSDDVIDNGNYDIE 646
RSAES++SL S +++ + P+ R +S R Q D + +
Sbjct: 598 QFRSAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQ 657
Query: 647 --IRQPPMSERTRRRVYNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSP--KDRLR 702
+R PMSERTRRR + ++ R HR RRSR+SRSDNAL+L +ER+ KDR
Sbjct: 658 EGVRIQPMSERTRRRATSRDD-NRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPP 716
Query: 703 LYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSW 762
L ++Y++F++ +S +E + DLYGQ SD LQN +R+ + E D W
Sbjct: 717 LRAREDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYD--W 774
Query: 763 CSSSSSSSDSEEEGYFLGQPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSK--KK 820
CS+ SSSS+S+ EGYFLG+PIPQP R+ +D+L S+ P+ + + +
Sbjct: 775 CSTCSSSSESDNEGYFLGEPIPQPARLRYV-TSDELLHKYSSYGLPKSSTLGGRGQLHSR 833
Query: 821 KGHKGKNCIIS 831
K K KNCIIS
Sbjct: 834 KRQKSKNCIIS 844
>gi|7710129 LIM domain only 6 [Homo sapiens]
Length = 615
Score = 484 bits (1245), Expect = e-136
Identities = 207/318 (65%), Positives = 255/318 (80%)
Query: 1 MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
+P+++E M +L QR S SDDDSGCA EEYAWVPPGL+PEQ+ +F+CLPE+KVPYV
Sbjct: 61 VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV 120
Query: 61 NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
NSPGEK+RIKQLL+QLPPHD+E +YC +L EEEKKEL+ FS QRK+E LGRG +++
Sbjct: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT 180
Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
+ A+CE+CG +I GG++AVFASRAG G CWHP CFVC TC ELLVDLIYFY GK++CG
Sbjct: 181 ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG 240
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RHHAE L+PRC ACDEIIF+ ECTEAEGRHWHM HFCC ECE LGGQRY+M+ RP CC
Sbjct: 241 RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC 300
Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
C+E+ +AEYC+ CGEHIG+D QM Y+GQHWHA++ CF C++C +LLG PFLP++G I
Sbjct: 301 ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI 360
Query: 301 YCSKTCSLGEDVHASDSS 318
+CS+ CSLG + A S
Sbjct: 361 FCSRACSLGSEPTAPGPS 378
Score = 40.0 bits (92), Expect = 0.009
Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 17/85 (20%)
Query: 756 GEDDDSWCSS--SSSSSDSEEEGYFLGQPIPQP----RP---QRFAYYTDDLSSPPSALP 806
G D +S SS SSSS SE++G+FLG+ IP P RP Q A T +SP +LP
Sbjct: 539 GSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMET--FNSPSLSLP 596
Query: 807 TPQFGQRTTKSKKKKGHKGKNCIIS 831
R +++ + + KNCI++
Sbjct: 597 ------RDSRAGMPRQARDKNCIVA 615
>gi|7661666 testin isoform 1 [Homo sapiens]
Length = 421
Score = 252 bits (643), Expect = 1e-66
Identities = 119/306 (38%), Positives = 173/306 (56%), Gaps = 32/306 (10%)
Query: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Y W PP + Y LP+EK P S G ++R KQL QLP HD + C LS
Sbjct: 111 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 170
Query: 93 EKKELQVFSAQRKKEALGRGTIKLL----------------SRAVMHAV----------- 125
E KE++ F + K EALG G +KL R+ AV
Sbjct: 171 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 230
Query: 126 -----CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
C C L + G+ A++A RAG WHP+CFVC TC+ELLVD+IYF+++ K++CG
Sbjct: 231 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RH+ + KPRC+ CDE+IF++E T+AE ++WH+KHFCC +C+++L G+ Y+M + +P C
Sbjct: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350
Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
C+ +A C+ C I + ++TY+ WHA+ CF C+ C L+G F+P +G +
Sbjct: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410
Query: 301 YCSKTC 306
+CS C
Sbjct: 411 FCSVEC 416
>gi|23238188 testin isoform 2 [Homo sapiens]
Length = 412
Score = 252 bits (643), Expect = 1e-66
Identities = 119/306 (38%), Positives = 173/306 (56%), Gaps = 32/306 (10%)
Query: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Y W PP + Y LP+EK P S G ++R KQL QLP HD + C LS
Sbjct: 102 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 161
Query: 93 EKKELQVFSAQRKKEALGRGTIKLL----------------SRAVMHAV----------- 125
E KE++ F + K EALG G +KL R+ AV
Sbjct: 162 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 221
Query: 126 -----CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
C C L + G+ A++A RAG WHP+CFVC TC+ELLVD+IYF+++ K++CG
Sbjct: 222 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 281
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RH+ + KPRC+ CDE+IF++E T+AE ++WH+KHFCC +C+++L G+ Y+M + +P C
Sbjct: 282 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 341
Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
C+ +A C+ C I + ++TY+ WHA+ CF C+ C L+G F+P +G +
Sbjct: 342 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 401
Query: 301 YCSKTC 306
+CS C
Sbjct: 402 FCSVEC 407
>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
Length = 384
Score = 222 bits (566), Expect = 1e-57
Identities = 108/230 (46%), Positives = 142/230 (61%), Gaps = 6/230 (2%)
Query: 20 STSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPH 79
+ SD DSG E P + L CL + P N G ++ LL QLPP
Sbjct: 24 ANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQTLLQQLPPQ 77
Query: 80 DNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLKINGGEVA 139
D + RYC +L EEE+ ELQ+F A+RK+EALG+G +L+ + CE+C + GE
Sbjct: 78 DIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYG 137
Query: 140 VFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF 199
VFA+RAG CWH CF C C + L++LIYFY DG+++CGRHHAELL+PRC ACD++IF
Sbjct: 138 VFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIF 197
Query: 200 ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAE 249
+ CTEAEG+ WH HFCC +C LGG RY + G P C CFE+ Y++
Sbjct: 198 SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/133 (26%), Positives = 45/133 (33%), Gaps = 13/133 (9%)
Query: 180 GRHHAELLKPR-----CSACDEIIFADE-----CTEAEGRHWHMKHFCCLECETVLGGQR 229
G+ A L+ P+ C C E++ E E R WH F C C L
Sbjct: 108 GQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLI 167
Query: 230 YIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLL 289
Y DG+ +C L C C + I +GQ WH C C C L
Sbjct: 168 YFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHENHFC--CQDCAGPLG 224
Query: 290 GCPFLPKQGQIYC 302
G + G C
Sbjct: 225 GGRYALPGGSPCC 237
Score = 35.0 bits (79), Expect = 0.29
Identities = 16/26 (61%), Positives = 21/26 (80%)
Query: 760 DSWCSSSSSSSDSEEEGYFLGQPIPQ 785
D+ S+ SSSSDSE EG+FLG+ +PQ
Sbjct: 336 DTPFSTCSSSSDSEPEGFFLGERLPQ 361
Score = 32.0 bits (71), Expect = 2.4
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 8/59 (13%)
Query: 251 CETCGEHI-----GVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
CE C E + GV A + + WH + CF+C C +L+ + GQ+YC +
Sbjct: 124 CEKCRELLKPGEYGV-FAARAGEQRCWH--QPCFACQACGQALINLIYFYHDGQLYCGR 179
>gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]
Length = 365
Score = 173 bits (439), Expect = 5e-43
Identities = 92/245 (37%), Positives = 124/245 (50%), Gaps = 32/245 (13%)
Query: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Y W PPG+ + Y +P+EK P + G +R +QL++QLP +D + C+ L E
Sbjct: 118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLEN 177
Query: 93 EKKELQVFSAQRKKEALGRGTIKLLSRAVM------------------------------ 122
E K ++ F Q K EALG G + L + +
Sbjct: 178 ELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK 237
Query: 123 --HAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
VCE C V++ RAG WHP+CFVC C+E LVDLIYF++DG CG
Sbjct: 238 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG 297
Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
RH+ E L+PRCS CDEIIFA++ E WH KHF C CE +L G+ YI+ G+ C
Sbjct: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
Query: 241 GCFES 245
C +S
Sbjct: 358 TCSKS 362
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 103 bits (257), Expect = 7e-22
Identities = 55/186 (29%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
C CG + G + G WH CF+C C + L + G +C +
Sbjct: 101 CSACGETVMPGSRKLEYG----GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYEN 156
Query: 186 LLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFES 245
PRC+ C + + T + + WH + C C+T L GQ++ +D P+C CF
Sbjct: 157 KFAPRCARCSKTLTQGGVTYRD-QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215
Query: 246 LYAEYCETCGEHI-GVDHAQ-MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
L+A C +C I G+ + ++++ +HWH CFSCA+C SL+G F+P Q+ C
Sbjct: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWH--HNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
Query: 304 KTCSLG 309
G
Sbjct: 274 GCSQAG 279
Score = 87.8 bits (216), Expect = 4e-17
Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 5/153 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF-ADECTEAEGR 209
+H CF C C L D + QD ++ C + +CSAC E + E G+
Sbjct: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
WH F C CE LG + ++ G +C C+E+ +A C C + + +TY
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTL--TQGGVTYRD 178
Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
Q WH C C C+ L G F + YC
Sbjct: 179 QPWH--RECLVCTGCQTPLAGQQFTSRDEDPYC 209
Score = 83.2 bits (204), Expect = 9e-16
Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 3/148 (2%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA-EGRHWHMK 214
F C CNE L Y D +C + C+ C ++I D E RH+H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
F C C+ L + + +D C C+ S ++ C CGE + ++ Y GQ WH
Sbjct: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWH- 123
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
E CF C+ C+ L F+P +G YC
Sbjct: 124 -EHCFLCSGCEQPLGSRSFVPDKGAHYC 150
Score = 73.6 bits (179), Expect = 7e-13
Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
F C +C L G++YI D P+C C+++ +A C C + IG D ++ Y+ +H+H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH-- 62
Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCS 303
E CF C +C+ SL PF + ++ C+
Sbjct: 63 EGCFRCCRCQRSLADEPFTCQDSELLCN 90
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 98.2 bits (243), Expect = 3e-20
Identities = 56/178 (31%), Positives = 78/178 (43%), Gaps = 11/178 (6%)
Query: 125 VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHA 184
+C C I G V G WHP FVC C+ L +F +DG C +
Sbjct: 227 LCGSCNKPIAGQVVTAL------GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYF 280
Query: 185 ELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
E PRC C++ I + A G HWH +HFCC+ C G + + ++GRP+C F
Sbjct: 281 ERFSPRCGFCNQPI-RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 339
Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
L+A C+ C I ++ WH CF C +C A G F +G+ C
Sbjct: 340 QLFAPRCQGCQGPILDNYISAL--SALWHPD--CFVCRECFAPFSGGSFFEHEGRPLC 393
Score = 80.5 bits (197), Expect = 6e-15
Identities = 47/155 (30%), Positives = 65/155 (41%), Gaps = 5/155 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WHP F C +C E D + ++G+ +C R +L PRC C I D A
Sbjct: 303 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL-DNYISAL 361
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTY 267
WH F C EC G + +GRP C F + C TCG + V ++
Sbjct: 362 SALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG--LPVTGRCVSA 419
Query: 268 DGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
G+ +H F+C C L F + G+ YC
Sbjct: 420 LGRRFHPDH--FTCTFCLRPLTKGSFQERAGKPYC 452
Score = 79.0 bits (193), Expect = 2e-14
Identities = 41/117 (35%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 188 KPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
K C +C++ I A + A GR WH +HF C C T LGG + KDG PFC C+ +
Sbjct: 225 KGLCGSCNKPI-AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 283
Query: 248 AEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
+ C C + I H +T G HWH C C C F ++G+ YC +
Sbjct: 284 SPRCGFCNQPI--RHKMVTALGTHWHPEHFC--CVSCGEPFGDEGFHEREGRPYCRR 336
Score = 59.7 bits (143), Expect = 1e-08
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
WHP CFVC C +F +G+ C H C+ C + C A GR
Sbjct: 365 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGRR 423
Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
+H HF C C L + + G+P+C CF L+
Sbjct: 424 FHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 98.2 bits (243), Expect = 3e-20
Identities = 56/178 (31%), Positives = 78/178 (43%), Gaps = 11/178 (6%)
Query: 125 VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHA 184
+C C I G V G WHP FVC C+ L +F +DG C +
Sbjct: 210 LCGSCNKPIAGQVVTAL------GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYF 263
Query: 185 ELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
E PRC C++ I + A G HWH +HFCC+ C G + + ++GRP+C F
Sbjct: 264 ERFSPRCGFCNQPI-RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 322
Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
L+A C+ C I ++ WH CF C +C A G F +G+ C
Sbjct: 323 QLFAPRCQGCQGPILDNYISAL--SALWHPD--CFVCRECFAPFSGGSFFEHEGRPLC 376
Score = 80.5 bits (197), Expect = 6e-15
Identities = 47/155 (30%), Positives = 65/155 (41%), Gaps = 5/155 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WHP F C +C E D + ++G+ +C R +L PRC C I D A
Sbjct: 286 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL-DNYISAL 344
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTY 267
WH F C EC G + +GRP C F + C TCG + V ++
Sbjct: 345 SALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG--LPVTGRCVSA 402
Query: 268 DGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
G+ +H F+C C L F + G+ YC
Sbjct: 403 LGRRFHPDH--FTCTFCLRPLTKGSFQERAGKPYC 435
Score = 79.0 bits (193), Expect = 2e-14
Identities = 41/117 (35%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
Query: 188 KPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
K C +C++ I A + A GR WH +HF C C T LGG + KDG PFC C+ +
Sbjct: 208 KGLCGSCNKPI-AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 266
Query: 248 AEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
+ C C + I H +T G HWH C C C F ++G+ YC +
Sbjct: 267 SPRCGFCNQPI--RHKMVTALGTHWHPEHFC--CVSCGEPFGDEGFHEREGRPYCRR 319
Score = 59.7 bits (143), Expect = 1e-08
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
WHP CFVC C +F +G+ C H C+ C + C A GR
Sbjct: 348 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGRR 406
Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
+H HF C C L + + G+P+C CF L+
Sbjct: 407 FHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 95.9 bits (237), Expect = 1e-19
Identities = 56/199 (28%), Positives = 84/199 (42%), Gaps = 12/199 (6%)
Query: 109 LGRGTIKLLSRAVMHA---VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELL 165
L RGT++ R + +C C I G + G WHP F C C L
Sbjct: 421 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAM------GRSWHPEEFTCAYCKTSL 474
Query: 166 VDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVL 225
D+ + + ++C R + + P C+ C+ I E A + WH F C C+
Sbjct: 475 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPF 533
Query: 226 GGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCK 285
G + M+DG P+C + +L++ C C + + G WH T CF CA C
Sbjct: 534 GNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT--CFICAVCH 591
Query: 286 ASLLGCPFLPKQGQIYCSK 304
+L G PF K+ + C K
Sbjct: 592 VNLEGQPFYSKKDRPLCKK 610
Score = 32.0 bits (71), Expect = 2.4
Identities = 14/57 (24%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRH 182
C C + G+ + A G WH +CF+C C+ L ++ + + C +H
Sbjct: 559 CHGCDFPVEAGDKFIEAL----GHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 611
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 95.9 bits (237), Expect = 1e-19
Identities = 56/199 (28%), Positives = 84/199 (42%), Gaps = 12/199 (6%)
Query: 109 LGRGTIKLLSRAVMHA---VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELL 165
L RGT++ R + +C C I G + G WHP F C C L
Sbjct: 531 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAM------GRSWHPEEFTCAYCKTSL 584
Query: 166 VDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVL 225
D+ + + ++C R + + P C+ C+ I E A + WH F C C+
Sbjct: 585 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPF 643
Query: 226 GGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCK 285
G + M+DG P+C + +L++ C C + + G WH T CF CA C
Sbjct: 644 GNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT--CFICAVCH 701
Query: 286 ASLLGCPFLPKQGQIYCSK 304
+L G PF K+ + C K
Sbjct: 702 VNLEGQPFYSKKDRPLCKK 720
Score = 32.0 bits (71), Expect = 2.4
Identities = 14/57 (24%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRH 182
C C + G+ + A G WH +CF+C C+ L ++ + + C +H
Sbjct: 669 CHGCDFPVEAGDKFIEAL----GHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 721
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 95.1 bits (235), Expect = 2e-19
Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
WH +CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
WH F C C+ V+G + K +C C E+ +A++C C + + +TY
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
Q WHA CF C C L G F + Q YC
Sbjct: 179 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 93.2 bits (230), Expect = 9e-19
Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH CF C C +++ +F + +C H C C++ I + T +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
+ WH F C+ C L GQR+ + + +C C+++ A+ C C I G +
Sbjct: 179 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ Y+GQ WH + CF C +C +L F+ Q Q+YC
Sbjct: 238 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 73.2 bits (178), Expect = 9e-13
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
F C C L G++Y+ KDG C CF+ A C C + IG D ++ Y + WH T
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
CF CA+C L F+ K +I C+K C+ ED
Sbjct: 65 --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
Score = 66.6 bits (161), Expect = 9e-11
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
F C +C L + ++ KD + C C + C+ C + I + Y G WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ CF+C+ CK + F PK YC
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
WH CFVC TC++ L + + + +C + + +C+ C I
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
EG+ WH F C +C L +R++ + +C C + L
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 95.1 bits (235), Expect = 2e-19
Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
WH +CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
WH F C C+ V+G + K +C C E+ +A++C C + + +TY
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
Q WHA CF C C L G F + Q YC
Sbjct: 179 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 73.2 bits (178), Expect = 9e-13
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
F C C L G++Y+ KDG C CF+ A C C + IG D ++ Y + WH T
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
CF CA+C L F+ K +I C+K C+ ED
Sbjct: 65 --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
Score = 66.6 bits (161), Expect = 9e-11
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
F C +C L + ++ KD + C C + C+ C + I + Y G WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ CF+C+ CK + F PK YC
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 65.1 bits (157), Expect = 3e-10
Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH CF C C +++ +F + +C H C C++ I + T +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETC 254
+ WH F C+ C L GQR+ + + +C C+++ A+ C C
Sbjct: 179 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 95.1 bits (235), Expect = 2e-19
Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
WH +CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
WH F C C+ V+G + K +C C E+ +A++C C + + +TY
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
Q WHA CF C C L G F + Q YC
Sbjct: 179 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 93.2 bits (230), Expect = 9e-19
Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH CF C C +++ +F + +C H C C++ I + T +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
+ WH F C+ C L GQR+ + + +C C+++ A+ C C I G +
Sbjct: 179 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ Y+GQ WH + CF C +C +L F+ Q Q+YC
Sbjct: 238 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 73.2 bits (178), Expect = 9e-13
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
F C C L G++Y+ KDG C CF+ A C C + IG D ++ Y + WH T
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
CF CA+C L F+ K +I C+K C+ ED
Sbjct: 65 --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
Score = 66.6 bits (161), Expect = 9e-11
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
F C +C L + ++ KD + C C + C+ C + I + Y G WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ CF+C+ CK + F PK YC
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
WH CFVC TC++ L + + + +C + + +C+ C I
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
EG+ WH F C +C L +R++ + +C C + L
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 95.1 bits (235), Expect = 2e-19
Identities = 57/188 (30%), Positives = 79/188 (42%), Gaps = 11/188 (5%)
Query: 115 KLLSRAVMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQD 174
KL V VC C I G V G WHP FVC C E + +F +D
Sbjct: 180 KLGVATVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERD 233
Query: 175 GKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKD 234
G+ +C + + L PRC C+ I D+ A R WH +HF C +C G + + KD
Sbjct: 234 GQPYCEKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 292
Query: 235 GRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFL 294
G+ +C + ++A C C I ++ WH CF C +C + F
Sbjct: 293 GKAYCRKDYFDMFAPKCGGCARAILENYISAL--NTLWH--PECFVCRECFTPFVNGSFF 348
Query: 295 PKQGQIYC 302
GQ YC
Sbjct: 349 EHDGQPYC 356
Score = 69.7 bits (169), Expect = 1e-11
Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Query: 184 AELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCF 243
A + K C AC + I A + A G+ WH +HF C C+ +G + + +DG+P+C +
Sbjct: 184 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242
Query: 244 ESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
+L++ C C I +D D + WH F CAQC A F K G+ YC
Sbjct: 243 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 298
Query: 304 K 304
K
Sbjct: 299 K 299
Score = 67.4 bits (163), Expect = 5e-11
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
WHP CFVC C V+ +F DG+ +C H+ E CS C + I C A +
Sbjct: 328 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 386
Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
+H +HF C C L + ++ +P+C CF L+
Sbjct: 387 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
Score = 63.2 bits (152), Expect = 1e-09
Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 5/152 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
WHP F C C + +DGK +C + + ++ P+C C I + A
Sbjct: 269 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 327
Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQ 270
WH + F C EC T + DG+P+C + C C + I +T +
Sbjct: 328 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRCITAMAK 385
Query: 271 HWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+H F CA C L F + + YC
Sbjct: 386 KFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 415
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 95.1 bits (235), Expect = 2e-19
Identities = 57/188 (30%), Positives = 79/188 (42%), Gaps = 11/188 (5%)
Query: 115 KLLSRAVMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQD 174
KL V VC C I G V G WHP FVC C E + +F +D
Sbjct: 313 KLGVATVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERD 366
Query: 175 GKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKD 234
G+ +C + + L PRC C+ I D+ A R WH +HF C +C G + + KD
Sbjct: 367 GQPYCEKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 425
Query: 235 GRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFL 294
G+ +C + ++A C C I ++ WH CF C +C + F
Sbjct: 426 GKAYCRKDYFDMFAPKCGGCARAILENYISAL--NTLWH--PECFVCRECFTPFVNGSFF 481
Query: 295 PKQGQIYC 302
GQ YC
Sbjct: 482 EHDGQPYC 489
Score = 69.7 bits (169), Expect = 1e-11
Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Query: 184 AELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCF 243
A + K C AC + I A + A G+ WH +HF C C+ +G + + +DG+P+C +
Sbjct: 317 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375
Query: 244 ESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
+L++ C C I +D D + WH F CAQC A F K G+ YC
Sbjct: 376 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 431
Query: 304 K 304
K
Sbjct: 432 K 432
Score = 67.4 bits (163), Expect = 5e-11
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
WHP CFVC C V+ +F DG+ +C H+ E CS C + I C A +
Sbjct: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 519
Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
+H +HF C C L + ++ +P+C CF L+
Sbjct: 520 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
Score = 63.2 bits (152), Expect = 1e-09
Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 5/152 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
WHP F C C + +DGK +C + + ++ P+C C I + A
Sbjct: 402 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 460
Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQ 270
WH + F C EC T + DG+P+C + C C + I +T +
Sbjct: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRCITAMAK 518
Query: 271 HWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+H F CA C L F + + YC
Sbjct: 519 KFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 548
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 95.1 bits (235), Expect = 2e-19
Identities = 57/188 (30%), Positives = 79/188 (42%), Gaps = 11/188 (5%)
Query: 115 KLLSRAVMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQD 174
KL V VC C I G V G WHP FVC C E + +F +D
Sbjct: 347 KLGVATVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERD 400
Query: 175 GKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKD 234
G+ +C + + L PRC C+ I D+ A R WH +HF C +C G + + KD
Sbjct: 401 GQPYCEKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 459
Query: 235 GRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFL 294
G+ +C + ++A C C I ++ WH CF C +C + F
Sbjct: 460 GKAYCRKDYFDMFAPKCGGCARAILENYISAL--NTLWH--PECFVCRECFTPFVNGSFF 515
Query: 295 PKQGQIYC 302
GQ YC
Sbjct: 516 EHDGQPYC 523
Score = 69.7 bits (169), Expect = 1e-11
Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Query: 184 AELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCF 243
A + K C AC + I A + A G+ WH +HF C C+ +G + + +DG+P+C +
Sbjct: 351 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 409
Query: 244 ESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
+L++ C C I +D D + WH F CAQC A F K G+ YC
Sbjct: 410 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 465
Query: 304 K 304
K
Sbjct: 466 K 466
Score = 67.4 bits (163), Expect = 5e-11
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
WHP CFVC C V+ +F DG+ +C H+ E CS C + I C A +
Sbjct: 495 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 553
Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
+H +HF C C L + ++ +P+C CF L+
Sbjct: 554 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
Score = 63.2 bits (152), Expect = 1e-09
Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 5/152 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
WHP F C C + +DGK +C + + ++ P+C C I + A
Sbjct: 436 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 494
Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQ 270
WH + F C EC T + DG+P+C + C C + I +T +
Sbjct: 495 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRCITAMAK 552
Query: 271 HWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+H F CA C L F + + YC
Sbjct: 553 KFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 582
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 95.1 bits (235), Expect = 2e-19
Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
WH +CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 90 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149
Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
WH F C C+ V+G + K +C C E+ +A++C C + + +TY
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 207
Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
Q WHA CF C C L G F + Q YC
Sbjct: 208 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 238
Score = 93.2 bits (230), Expect = 9e-19
Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH CF C C +++ +F + +C H C C++ I + T +
Sbjct: 148 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 207
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
+ WH F C+ C L GQR+ + + +C C+++ A+ C C I G +
Sbjct: 208 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 266
Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ Y+GQ WH + CF C +C +L F+ Q Q+YC
Sbjct: 267 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 302
Score = 73.2 bits (178), Expect = 9e-13
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
F C C L G++Y+ KDG C CF+ A C C + IG D ++ Y + WH T
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93
Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
CF CA+C L F+ K +I C+K C+ ED
Sbjct: 94 --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 126
Score = 66.6 bits (161), Expect = 9e-11
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
F C +C L + ++ KD + C C + C+ C + I + Y G WH
Sbjct: 94 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 152
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ CF+C+ CK + F PK YC
Sbjct: 153 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 179
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
WH CFVC TC++ L + + + +C + + +C+ C I
Sbjct: 210 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 269
Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
EG+ WH F C +C L +R++ + +C C + L
Sbjct: 270 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 309
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 95.1 bits (235), Expect = 2e-19
Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
WH +CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
WH F C C+ V+G + K +C C E+ +A++C C + + +TY
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 194
Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
Q WHA CF C C L G F + Q YC
Sbjct: 195 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 225
Score = 93.2 bits (230), Expect = 9e-19
Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH CF C C +++ +F + +C H C C++ I + T +
Sbjct: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
+ WH F C+ C L GQR+ + + +C C+++ A+ C C I G +
Sbjct: 195 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 253
Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ Y+GQ WH + CF C +C +L F+ Q Q+YC
Sbjct: 254 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 289
Score = 73.2 bits (178), Expect = 9e-13
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
F C C L G++Y+ KDG C CF+ A C C + IG D ++ Y + WH T
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
CF CA+C L F+ K +I C+K C+ ED
Sbjct: 81 --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 113
Score = 66.6 bits (161), Expect = 9e-11
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
F C +C L + ++ KD + C C + C+ C + I + Y G WH
Sbjct: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 139
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ CF+C+ CK + F PK YC
Sbjct: 140 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 166
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
WH CFVC TC++ L + + + +C + + +C+ C I
Sbjct: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
EG+ WH F C +C L +R++ + +C C + L
Sbjct: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 95.1 bits (235), Expect = 2e-19
Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
WH +CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
WH F C C+ V+G + K +C C E+ +A++C C + + +TY
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
Q WHA CF C C L G F + Q YC
Sbjct: 179 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 93.2 bits (230), Expect = 9e-19
Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH CF C C +++ +F + +C H C C++ I + T +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
+ WH F C+ C L GQR+ + + +C C+++ A+ C C I G +
Sbjct: 179 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ Y+GQ WH + CF C +C +L F+ Q Q+YC
Sbjct: 238 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 73.2 bits (178), Expect = 9e-13
Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
F C C L G++Y+ KDG C CF+ A C C + IG D ++ Y + WH T
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
CF CA+C L F+ K +I C+K C+ ED
Sbjct: 65 --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
Score = 66.6 bits (161), Expect = 9e-11
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
F C +C L + ++ KD + C C + C+ C + I + Y G WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
+ CF+C+ CK + F PK YC
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
WH CFVC TC++ L + + + +C + + +C+ C I
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
EG+ WH F C +C L +R++ + +C C + L
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 93.6 bits (231), Expect = 7e-19
Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 2/90 (2%)
Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
+ F C C L G++YI+++ P+C CFE+L+A CE CG+ IG D ++Y +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
EACF C+QC+ SL+ PF K+ Q+ C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 89.0 bits (219), Expect = 2e-17
Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
CE+CG I G + + + WH +CF C C LVD + ++ ++ C ++
Sbjct: 40 CEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSN 95
Query: 186 LLKPRCSACDEIIF-ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
+C C + I E +G WH F C C+ +G + +I KD + FC C+E
Sbjct: 96 EYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYE 155
Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+A C C + I +TY Q WH + CF C C+ L G F + YC
Sbjct: 156 KQHAMQCVQCKKPITT--GGVTYREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 88.6 bits (218), Expect = 2e-17
Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH +CF+C C + + + +D + C + + +C C + I T E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
+ WH + F C C L GQR+ +D +C CF LYA+ C C I G+ + +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237
Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+++ + WH CF+C +C SL+G FL ++ I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 80.5 bits (197), Expect = 6e-15
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 5/149 (3%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA--EGRHWHM 213
F C CNE L Y ++ +C L C C + I D C + + RHWH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCD-CKDLSYKDRHWHE 63
Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
F C +C L + + K+ + C C+ + Y+ C+ C + I +M Y G WH
Sbjct: 64 ACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWH 123
Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYC 302
E CF C +C+ + F+PK Q +C
Sbjct: 124 --ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 123 HAV-CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGR 181
HA+ C QC I G V R P WH CFVC C + L + +D +C
Sbjct: 158 HAMQCVQCKKPITTGGVTY---REQP---WHKECFVCTACRKQLSGQRFTARDDFAYCLN 211
Query: 182 HHAELLKPRCSACDEIIFADECTEA---EGRHWHMKHFCCLECETVLGGQRYIMKDGRPF 238
+L +C+ C I T+ E R WH F C +C L G+ ++ +
Sbjct: 212 CFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDIL 271
Query: 239 CCGC 242
C C
Sbjct: 272 CPDC 275
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 93.6 bits (231), Expect = 7e-19
Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 2/90 (2%)
Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
+ F C C L G++YI+++ P+C CFE+L+A CE CG+ IG D ++Y +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
EACF C+QC+ SL+ PF K+ Q+ C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 89.0 bits (219), Expect = 2e-17
Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
CE+CG I G + + + WH +CF C C LVD + ++ ++ C ++
Sbjct: 40 CEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSN 95
Query: 186 LLKPRCSACDEIIF-ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
+C C + I E +G WH F C C+ +G + +I KD + FC C+E
Sbjct: 96 EYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYE 155
Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+A C C + I +TY Q WH + CF C C+ L G F + YC
Sbjct: 156 KQHAMQCVQCKKPITT--GGVTYREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 88.6 bits (218), Expect = 2e-17
Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH +CF+C C + + + +D + C + + +C C + I T E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
+ WH + F C C L GQR+ +D +C CF LYA+ C C I G+ + +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237
Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+++ + WH CF+C +C SL+G FL ++ I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 80.5 bits (197), Expect = 6e-15
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 5/149 (3%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA--EGRHWHM 213
F C CNE L Y ++ +C L C C + I D C + + RHWH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCD-CKDLSYKDRHWHE 63
Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
F C +C L + + K+ + C C+ + Y+ C+ C + I +M Y G WH
Sbjct: 64 ACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWH 123
Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYC 302
E CF C +C+ + F+PK Q +C
Sbjct: 124 --ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 123 HAV-CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGR 181
HA+ C QC I G V R P WH CFVC C + L + +D +C
Sbjct: 158 HAMQCVQCKKPITTGGVTY---REQP---WHKECFVCTACRKQLSGQRFTARDDFAYCLN 211
Query: 182 HHAELLKPRCSACDEIIFADECTEA---EGRHWHMKHFCCLECETVLGGQRYIMKDGRPF 238
+L +C+ C I T+ E R WH F C +C L G+ ++ +
Sbjct: 212 CFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDIL 271
Query: 239 CCGC 242
C C
Sbjct: 272 CPDC 275
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 93.6 bits (231), Expect = 7e-19
Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 2/90 (2%)
Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
+ F C C L G++YI+++ P+C CFE+L+A CE CG+ IG D ++Y +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
EACF C+QC+ SL+ PF K+ Q+ C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 89.0 bits (219), Expect = 2e-17
Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
CE+CG I G + + + WH +CF C C LVD + ++ ++ C ++
Sbjct: 40 CEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSN 95
Query: 186 LLKPRCSACDEIIF-ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
+C C + I E +G WH F C C+ +G + +I KD + FC C+E
Sbjct: 96 EYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYE 155
Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+A C C + I +TY Q WH + CF C C+ L G F + YC
Sbjct: 156 KQHAMQCVQCKKPITT--GGVTYREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 88.6 bits (218), Expect = 2e-17
Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH +CF+C C + + + +D + C + + +C C + I T E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
+ WH + F C C L GQR+ +D +C CF LYA+ C C I G+ + +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237
Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+++ + WH CF+C +C SL+G FL ++ I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 80.5 bits (197), Expect = 6e-15
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 5/149 (3%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA--EGRHWHM 213
F C CNE L Y ++ +C L C C + I D C + + RHWH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCD-CKDLSYKDRHWHE 63
Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
F C +C L + + K+ + C C+ + Y+ C+ C + I +M Y G WH
Sbjct: 64 ACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWH 123
Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYC 302
E CF C +C+ + F+PK Q +C
Sbjct: 124 --ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 123 HAV-CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGR 181
HA+ C QC I G V R P WH CFVC C + L + +D +C
Sbjct: 158 HAMQCVQCKKPITTGGVTY---REQP---WHKECFVCTACRKQLSGQRFTARDDFAYCLN 211
Query: 182 HHAELLKPRCSACDEIIFADECTEA---EGRHWHMKHFCCLECETVLGGQRYIMKDGRPF 238
+L +C+ C I T+ E R WH F C +C L G+ ++ +
Sbjct: 212 CFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDIL 271
Query: 239 CCGC 242
C C
Sbjct: 272 CPDC 275
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 93.6 bits (231), Expect = 7e-19
Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 2/90 (2%)
Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
+ F C C L G++YI+++ P+C CFE+L+A CE CG+ IG D ++Y +HWH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
EACF C+QC+ SL+ PF K+ Q+ C+
Sbjct: 63 --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90
Score = 89.0 bits (219), Expect = 2e-17
Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
CE+CG I G + + + WH +CF C C LVD + ++ ++ C ++
Sbjct: 40 CEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSN 95
Query: 186 LLKPRCSACDEIIF-ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
+C C + I E +G WH F C C+ +G + +I KD + FC C+E
Sbjct: 96 EYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYE 155
Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+A C C + I +TY Q WH + CF C C+ L G F + YC
Sbjct: 156 KQHAMQCVQCKKPITT--GGVTYREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 88.6 bits (218), Expect = 2e-17
Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH +CF+C C + + + +D + C + + +C C + I T E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
+ WH + F C C L GQR+ +D +C CF LYA+ C C I G+ + +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237
Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
+++ + WH CF+C +C SL+G FL ++ I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 80.5 bits (197), Expect = 6e-15
Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 5/149 (3%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA--EGRHWHM 213
F C CNE L Y ++ +C L C C + I D C + + RHWH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCD-CKDLSYKDRHWHE 63
Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
F C +C L + + K+ + C C+ + Y+ C+ C + I +M Y G WH
Sbjct: 64 ACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWH 123
Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYC 302
E CF C +C+ + F+PK Q +C
Sbjct: 124 --ETCFICHRCQQPIGTKSFIPKDNQNFC 150
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)
Query: 123 HAV-CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGR 181
HA+ C QC I G V R P WH CFVC C + L + +D +C
Sbjct: 158 HAMQCVQCKKPITTGGVTY---REQP---WHKECFVCTACRKQLSGQRFTARDDFAYCLN 211
Query: 182 HHAELLKPRCSACDEIIFADECTEA---EGRHWHMKHFCCLECETVLGGQRYIMKDGRPF 238
+L +C+ C I T+ E R WH F C +C L G+ ++ +
Sbjct: 212 CFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDIL 271
Query: 239 CCGC 242
C C
Sbjct: 272 CPDC 275
>gi|30410801 activator of cAMP-responsive element modulator (CREM)
in testis [Homo sapiens]
Length = 284
Score = 90.1 bits (222), Expect = 8e-18
Identities = 49/166 (29%), Positives = 81/166 (48%), Gaps = 6/166 (3%)
Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
G WH +CFVC C + + ++ +C + C+ C ++I + T +
Sbjct: 120 GNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCD 179
Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
+ WH + F C C L ++++ +D PFC C+ LYA C C + I G+ A+ +
Sbjct: 180 -QLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFI 238
Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
+ WH+ CF+C +C SL+G FL + +I+C K C G D
Sbjct: 239 CFQDSQWHS--ECFNCGKCSVSLVGKGFLTQNKEIFCQK-CGSGMD 281
Score = 85.9 bits (211), Expect = 1e-16
Identities = 44/153 (28%), Positives = 68/153 (44%), Gaps = 5/153 (3%)
Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF-ADECTEAEGR 209
WH CF C CN LV+ + +D ++ C ++ +C C I E +G
Sbjct: 62 WHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGN 121
Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
+WH F C C +G + I K+ +C CFE +A YC C + I +T+
Sbjct: 122 YWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI--TSGGITFCD 179
Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
Q WH + CF C+ C+ L F+ + +C
Sbjct: 180 QLWH--KECFLCSGCRKDLCEEQFMSRDDYPFC 210
Score = 84.7 bits (208), Expect = 3e-16
Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 15/149 (10%)
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
HF C C L G++Y++KD P+C C++ +++ YCE C + I D + Y +HWH
Sbjct: 5 HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWH- 63
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGEDVHASDSSDSAFQSARS--RDSRR 332
E CF C +C SL+ PF K ++ C+ + ++++ S F R+ SR+
Sbjct: 64 -EGCFKCTKCNHSLVEKPFAAKDERLLCT-------ECYSNECSSKCFHCKRTIMPGSRK 115
Query: 333 SVRMG----KSSRSADQCRQSLLLSPALN 357
G ++ + CRQ + P ++
Sbjct: 116 MEFKGNYWHETCFVCENCRQPIGTKPLIS 144
Score = 70.5 bits (171), Expect = 6e-12
Identities = 40/148 (27%), Positives = 61/148 (41%), Gaps = 3/148 (2%)
Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA-EGRHWHMK 214
F C C L+ Y +D +C + + C C + I +D + RHWH
Sbjct: 6 FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
F C +C L + + KD R C C+ + + C C I +M + G +WH
Sbjct: 66 CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH- 124
Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
E CF C C+ + P + K+ YC
Sbjct: 125 -ETCFVCENCRQPIGTKPLISKESGNYC 151
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 86.3 bits (212), Expect = 1e-16
Identities = 52/178 (29%), Positives = 78/178 (43%), Gaps = 9/178 (5%)
Query: 125 VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHA 184
VC QC I G + G +HP FVC C ++L + +F + G I C +
Sbjct: 247 VCHQCHKVIRGRYLVAL------GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYD 300
Query: 185 ELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
P C+ C + I E A WH+ F C C+T + + + M++G P+C +E
Sbjct: 301 VRYAPSCAKCKKKI-TGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYE 359
Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
++ C C I + G WH T CF CA C+ +L G F K+ + C
Sbjct: 360 KMFGTKCHGCDFKIDAGDRFLEALGFSWHDT--CFVCAICQINLEGKTFYSKKDRPLC 415
Score = 57.4 bits (137), Expect = 5e-08
Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 11/119 (9%)
Query: 189 PRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYA 248
P C C ++I A G +H + F C +C VL + + G FC C++ YA
Sbjct: 246 PVCHQCHKVI-RGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304
Query: 249 EYCETCGEHIG--VDHA-QMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
C C + I + HA +MT WH CF+CA CK + F ++G YC +
Sbjct: 305 PSCAKCKKKITGEIMHALKMT-----WHVH--CFTCAACKTPIRNRAFYMEEGVPYCER 356
Score = 33.5 bits (75), Expect = 0.83
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 4/57 (7%)
Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRH 182
C C KI+ G+ + A G WH +CFVC C L ++ + + C H
Sbjct: 366 CHGCDFKIDAGDRFLEAL----GFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,844,293
Number of Sequences: 37866
Number of extensions: 1803108
Number of successful extensions: 7708
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 192
Number of HSP's that attempted gapping in prelim test: 6701
Number of HSP's gapped (non-prelim): 749
length of query: 831
length of database: 18,247,518
effective HSP length: 111
effective length of query: 720
effective length of database: 14,044,392
effective search space: 10111962240
effective search space used: 10111962240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.