Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 222136684

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222136684 prickle homolog 1 [Homo sapiens]
         (831 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222136684 prickle homolog 1 [Homo sapiens]                        1731   0.0  
gi|222136682 prickle homolog 1 [Homo sapiens]                        1731   0.0  
gi|222136680 prickle homolog 1 [Homo sapiens]                        1731   0.0  
gi|222136678 prickle homolog 1 [Homo sapiens]                        1731   0.0  
gi|38524620 prickle-like 2 [Homo sapiens]                             766   0.0  
gi|7710129 LIM domain only 6 [Homo sapiens]                           484   e-136
gi|7661666 testin isoform 1 [Homo sapiens]                            252   1e-66
gi|23238188 testin isoform 2 [Homo sapiens]                           252   1e-66
gi|118722347 over-expressed breast tumor protein [Homo sapiens]       222   1e-57
gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]             173   5e-43
gi|54112385 four and a half LIM domains 3 [Homo sapiens]              103   7e-22
gi|109638745 transforming growth factor beta 1 induced transcrip...    98   3e-20
gi|21361591 transforming growth factor beta 1 induced transcript...    98   3e-20
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]             96   1e-19
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              96   1e-19
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]    95   2e-19
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]    95   2e-19
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]    95   2e-19
gi|170932518 paxillin isoform 3 [Homo sapiens]                         95   2e-19
gi|170932516 paxillin isoform 2 [Homo sapiens]                         95   2e-19
gi|170932514 paxillin isoform 1 [Homo sapiens]                         95   2e-19
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]    95   2e-19
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]    95   2e-19
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]     95   2e-19
gi|87159836 four and a half LIM domains 2 [Homo sapiens]               94   7e-19
gi|87159834 four and a half LIM domains 2 [Homo sapiens]               94   7e-19
gi|42403575 four and a half LIM domains 2 [Homo sapiens]               94   7e-19
gi|87159832 four and a half LIM domains 2 [Homo sapiens]               94   7e-19
gi|30410801 activator of cAMP-responsive element modulator (CREM...    90   8e-18
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]              86   1e-16

>gi|222136684 prickle homolog 1 [Homo sapiens]
          Length = 831

 Score = 1731 bits (4483), Expect = 0.0
 Identities = 831/831 (100%), Positives = 831/831 (100%)

Query: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
           MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
Sbjct: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60

Query: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
           NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
Sbjct: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120

Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
           VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240

Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
           GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300

Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
           YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360

Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
           PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420

Query: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
           KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480

Query: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
           GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
Sbjct: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540

Query: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
           ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
Sbjct: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600

Query: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
           ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
Sbjct: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660

Query: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
           YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
Sbjct: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720

Query: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
           IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
Sbjct: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780

Query: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
           QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS
Sbjct: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831


>gi|222136682 prickle homolog 1 [Homo sapiens]
          Length = 831

 Score = 1731 bits (4483), Expect = 0.0
 Identities = 831/831 (100%), Positives = 831/831 (100%)

Query: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
           MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
Sbjct: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60

Query: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
           NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
Sbjct: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120

Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
           VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240

Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
           GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300

Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
           YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360

Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
           PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420

Query: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
           KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480

Query: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
           GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
Sbjct: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540

Query: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
           ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
Sbjct: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600

Query: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
           ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
Sbjct: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660

Query: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
           YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
Sbjct: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720

Query: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
           IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
Sbjct: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780

Query: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
           QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS
Sbjct: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831


>gi|222136680 prickle homolog 1 [Homo sapiens]
          Length = 831

 Score = 1731 bits (4483), Expect = 0.0
 Identities = 831/831 (100%), Positives = 831/831 (100%)

Query: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
           MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
Sbjct: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60

Query: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
           NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
Sbjct: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120

Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
           VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240

Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
           GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300

Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
           YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360

Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
           PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420

Query: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
           KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480

Query: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
           GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
Sbjct: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540

Query: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
           ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
Sbjct: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600

Query: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
           ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
Sbjct: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660

Query: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
           YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
Sbjct: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720

Query: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
           IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
Sbjct: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780

Query: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
           QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS
Sbjct: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831


>gi|222136678 prickle homolog 1 [Homo sapiens]
          Length = 831

 Score = 1731 bits (4483), Expect = 0.0
 Identities = 831/831 (100%), Positives = 831/831 (100%)

Query: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
           MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV
Sbjct: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60

Query: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
           NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA
Sbjct: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120

Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
           VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG
Sbjct: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240

Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
           GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI
Sbjct: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300

Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
           YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF
Sbjct: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360

Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
           PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL
Sbjct: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420

Query: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480
           KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL
Sbjct: 421 KFGDKSLFQPQPNEMDIRASEHWISDNMVKSKTELKQNNQSLASKKYQSDMYWAQSQDGL 480

Query: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540
           GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL
Sbjct: 481 GDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKPEQSVRDSMDSL 540

Query: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600
           ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS
Sbjct: 541 ALSNITGASVDGENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSMLHRSAESLKSLSS 600

Query: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660
           ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV
Sbjct: 601 ELCPEKILPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGNYDIEIRQPPMSERTRRRV 660

Query: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720
           YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE
Sbjct: 661 YNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSARE 720

Query: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780
           IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG
Sbjct: 721 IQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSWCSSSSSSSDSEEEGYFLG 780

Query: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831
           QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS
Sbjct: 781 QPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSKKKKGHKGKNCIIS 831


>gi|38524620 prickle-like 2 [Homo sapiens]
          Length = 844

 Score =  766 bits (1979), Expect = 0.0
 Identities = 429/851 (50%), Positives = 542/851 (63%), Gaps = 31/851 (3%)

Query: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
           MPLEME  +SKL F  QR+STSDDDSGCALEEYAWVPPGL+PEQ+  Y++CLPEEKVPYV
Sbjct: 5   MPLEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYV 64

Query: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
           NSPGEK RIKQLL+QLPPHDNEVRYC SL EEEK+EL++FS+QRK+E LGRG ++     
Sbjct: 65  NSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVT 124

Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
           +  A+CEQCG +INGG++AVFASRAG GVCWHP CFVC  CNELLVDLIYFYQDGKI+CG
Sbjct: 125 MTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RHHAE LKPRC+ACDEIIFADECTEAEGRHWHMKHFCC ECETVLGGQRYIMK+GRP+CC
Sbjct: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244

Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
            CFESLYAEYC+TC +HIG+D  QMTYDGQHWHATE CF CA CK SLLG PFLPKQGQI
Sbjct: 245 HCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQI 304

Query: 301 YCSKTCSLGEDVHASDSSDSAFQSARSRDSRRSVRMGKSSRSADQCRQSLLLSPALNYKF 360
           +CS+ CS GED + SDSSDSAFQ+AR+++SRRS ++GK+    ++    L     L    
Sbjct: 305 FCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEE--PMLNQHSQLQVSS 362

Query: 361 PGLSGNADDTLSRKLDDLSLSRQGTSFASEEFWKGRVEQETPEDPEEWADHEDYMTQLLL 420
             LS +  D LS ++D LSLS Q  S   +  W+ R E     +  E    +  + QLL 
Sbjct: 363 NRLSADV-DPLSLQMDMLSLSSQTPSLNRDPIWRSREEPYHYGNKMEQNQTQSPL-QLLS 420

Query: 421 KFGDKSLFQPQPNEMDIRASEHWIS--DNMVKSKTELKQNNQSLASKKYQSDMY-----W 473
           +   ++ + P       +  E W     N  +S +     +     K+ + D Y      
Sbjct: 421 QCNIRTSYSPGGQGAGAQ-PEMWGKHFSNPKRSSSLAMTGHAGSFIKECREDYYPGRLRS 479

Query: 474 AQSQDGLGDSAYGSHPGPASSRRLQELELDHGASGYNHDETQWYEDSLECLSDLKP-EQS 532
            +S   +   ++    G     + +E E + G        T+    SL+   D+ P EQ+
Sbjct: 480 QESYSDMSSQSFSETRGSIQVPKYEEEEEEEGGLSTQQCRTRHPISSLKYTEDMTPTEQT 539

Query: 533 VRDSMDSLALSNITGASVDG-----ENKPRPSLYSLQNFEEMETEDCEKMSNMGTLNSSM 587
            R SM+SLALSN TG S DG     E+  R S+  L     M     EK+SNMGTLNSSM
Sbjct: 540 PRGSMESLALSNATGLSADGGAKRQEHLSRFSMPDLSKDSGMNVS--EKLSNMGTLNSSM 597

Query: 588 LHRSAESLKSLSSELCPEKILPEEKPVHLPV-LRRSKSQSRPQQVKFSDDVIDNGNYDIE 646
             RSAES++SL S    +++      +  P+  R  +S  R  Q    D  +       +
Sbjct: 598 QFRSAESVRSLLSAQQYQEMEGNLHQLSNPIGYRDLQSHGRMHQSFDFDGGMAGSKLPGQ 657

Query: 647 --IRQPPMSERTRRRVYNFEERGSRSHHHRRRRSRKSRSDNALNLVTERKYSP--KDRLR 702
             +R  PMSERTRRR  + ++   R   HR RRSR+SRSDNAL+L +ER+     KDR  
Sbjct: 658 EGVRIQPMSERTRRRATSRDD-NRRFRPHRSRRSRRSRSDNALHLASEREAISRLKDRPP 716

Query: 703 LYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATSDYGLQNPGMNRFLGLYGEDDDSW 762
           L   ++Y++F++ +S +E   +    DLYGQ     SD  LQN   +R+   + E D  W
Sbjct: 717 LRAREDYDQFMRQRSFQESMGHGSRRDLYGQCPRTVSDLALQNAFGDRWGPYFAEYD--W 774

Query: 763 CSSSSSSSDSEEEGYFLGQPIPQPRPQRFAYYTDDLSSPPSALPTPQFGQRTTKSK--KK 820
           CS+ SSSS+S+ EGYFLG+PIPQP   R+   +D+L    S+   P+      + +   +
Sbjct: 775 CSTCSSSSESDNEGYFLGEPIPQPARLRYV-TSDELLHKYSSYGLPKSSTLGGRGQLHSR 833

Query: 821 KGHKGKNCIIS 831
           K  K KNCIIS
Sbjct: 834 KRQKSKNCIIS 844


>gi|7710129 LIM domain only 6 [Homo sapiens]
          Length = 615

 Score =  484 bits (1245), Expect = e-136
 Identities = 207/318 (65%), Positives = 255/318 (80%)

Query: 1   MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYV 60
           +P+++E  M +L    QR S SDDDSGCA EEYAWVPPGL+PEQ+  +F+CLPE+KVPYV
Sbjct: 61  VPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYV 120

Query: 61  NSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRA 120
           NSPGEK+RIKQLL+QLPPHD+E +YC +L EEEKKEL+ FS QRK+E LGRG +++    
Sbjct: 121 NSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVT 180

Query: 121 VMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
           +  A+CE+CG +I GG++AVFASRAG G CWHP CFVC TC ELLVDLIYFY  GK++CG
Sbjct: 181 ITGAICEECGKQIGGGDIAVFASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCG 240

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RHHAE L+PRC ACDEIIF+ ECTEAEGRHWHM HFCC ECE  LGGQRY+M+  RP CC
Sbjct: 241 RHHAECLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCC 300

Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
            C+E+ +AEYC+ CGEHIG+D  QM Y+GQHWHA++ CF C++C  +LLG PFLP++G I
Sbjct: 301 ACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLI 360

Query: 301 YCSKTCSLGEDVHASDSS 318
           +CS+ CSLG +  A   S
Sbjct: 361 FCSRACSLGSEPTAPGPS 378



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 17/85 (20%)

Query: 756 GEDDDSWCSS--SSSSSDSEEEGYFLGQPIPQP----RP---QRFAYYTDDLSSPPSALP 806
           G D +S  SS  SSSS  SE++G+FLG+ IP P    RP   Q  A  T   +SP  +LP
Sbjct: 539 GSDSESCSSSPSSSSSESSEDDGFFLGERIPLPPHLCRPMPAQDTAMET--FNSPSLSLP 596

Query: 807 TPQFGQRTTKSKKKKGHKGKNCIIS 831
                 R +++   +  + KNCI++
Sbjct: 597 ------RDSRAGMPRQARDKNCIVA 615


>gi|7661666 testin isoform 1 [Homo sapiens]
          Length = 421

 Score =  252 bits (643), Expect = 1e-66
 Identities = 119/306 (38%), Positives = 173/306 (56%), Gaps = 32/306 (10%)

Query: 33  YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
           Y W PP       + Y   LP+EK P   S G ++R KQL  QLP HD +   C  LS  
Sbjct: 111 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 170

Query: 93  EKKELQVFSAQRKKEALGRGTIKLL----------------SRAVMHAV----------- 125
           E KE++ F  + K EALG G +KL                  R+   AV           
Sbjct: 171 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 230

Query: 126 -----CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
                C  C L +  G+ A++A RAG    WHP+CFVC TC+ELLVD+IYF+++ K++CG
Sbjct: 231 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 290

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RH+ +  KPRC+ CDE+IF++E T+AE ++WH+KHFCC +C+++L G+ Y+M + +P C 
Sbjct: 291 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 350

Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
            C+   +A  C+ C   I  +  ++TY+   WHA+  CF C+ C   L+G  F+P +G +
Sbjct: 351 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 410

Query: 301 YCSKTC 306
           +CS  C
Sbjct: 411 FCSVEC 416


>gi|23238188 testin isoform 2 [Homo sapiens]
          Length = 412

 Score =  252 bits (643), Expect = 1e-66
 Identities = 119/306 (38%), Positives = 173/306 (56%), Gaps = 32/306 (10%)

Query: 33  YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
           Y W PP       + Y   LP+EK P   S G ++R KQL  QLP HD +   C  LS  
Sbjct: 102 YEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPR 161

Query: 93  EKKELQVFSAQRKKEALGRGTIKLL----------------SRAVMHAV----------- 125
           E KE++ F  + K EALG G +KL                  R+   AV           
Sbjct: 162 EVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK 221

Query: 126 -----CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
                C  C L +  G+ A++A RAG    WHP+CFVC TC+ELLVD+IYF+++ K++CG
Sbjct: 222 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG 281

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RH+ +  KPRC+ CDE+IF++E T+AE ++WH+KHFCC +C+++L G+ Y+M + +P C 
Sbjct: 282 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK 341

Query: 241 GCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQI 300
            C+   +A  C+ C   I  +  ++TY+   WHA+  CF C+ C   L+G  F+P +G +
Sbjct: 342 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV 401

Query: 301 YCSKTC 306
           +CS  C
Sbjct: 402 FCSVEC 407


>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
          Length = 384

 Score =  222 bits (566), Expect = 1e-57
 Identities = 108/230 (46%), Positives = 142/230 (61%), Gaps = 6/230 (2%)

Query: 20  STSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPH 79
           + SD DSG    E         P  + L   CL   + P  N  G    ++ LL QLPP 
Sbjct: 24  ANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQTLLQQLPPQ 77

Query: 80  DNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLKINGGEVA 139
           D + RYC +L EEE+ ELQ+F A+RK+EALG+G  +L+   +    CE+C   +  GE  
Sbjct: 78  DIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYG 137

Query: 140 VFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF 199
           VFA+RAG   CWH  CF C  C + L++LIYFY DG+++CGRHHAELL+PRC ACD++IF
Sbjct: 138 VFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIF 197

Query: 200 ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAE 249
           +  CTEAEG+ WH  HFCC +C   LGG RY +  G P C  CFE+ Y++
Sbjct: 198 SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/133 (26%), Positives = 45/133 (33%), Gaps = 13/133 (9%)

Query: 180 GRHHAELLKPR-----CSACDEIIFADE-----CTEAEGRHWHMKHFCCLECETVLGGQR 229
           G+  A L+ P+     C  C E++   E         E R WH   F C  C   L    
Sbjct: 108 GQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLI 167

Query: 230 YIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLL 289
           Y   DG+ +C      L    C  C + I         +GQ WH    C  C  C   L 
Sbjct: 168 YFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHENHFC--CQDCAGPLG 224

Query: 290 GCPFLPKQGQIYC 302
           G  +    G   C
Sbjct: 225 GGRYALPGGSPCC 237



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 16/26 (61%), Positives = 21/26 (80%)

Query: 760 DSWCSSSSSSSDSEEEGYFLGQPIPQ 785
           D+  S+ SSSSDSE EG+FLG+ +PQ
Sbjct: 336 DTPFSTCSSSSDSEPEGFFLGERLPQ 361



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 251 CETCGEHI-----GVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
           CE C E +     GV  A    + + WH  + CF+C  C  +L+   +    GQ+YC +
Sbjct: 124 CEKCRELLKPGEYGV-FAARAGEQRCWH--QPCFACQACGQALINLIYFYHDGQLYCGR 179


>gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]
          Length = 365

 Score =  173 bits (439), Expect = 5e-43
 Identities = 92/245 (37%), Positives = 124/245 (50%), Gaps = 32/245 (13%)

Query: 33  YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
           Y W PPG+  +    Y   +P+EK P   + G  +R +QL++QLP +D +   C+ L E 
Sbjct: 118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLEN 177

Query: 93  EKKELQVFSAQRKKEALGRGTIKLLSRAVM------------------------------ 122
           E K ++ F  Q K EALG G + L  +  +                              
Sbjct: 178 ELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK 237

Query: 123 --HAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
               VCE C          V++ RAG    WHP+CFVC  C+E LVDLIYF++DG   CG
Sbjct: 238 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG 297

Query: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
           RH+ E L+PRCS CDEIIFA++    E   WH KHF C  CE +L G+ YI+  G+  C 
Sbjct: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357

Query: 241 GCFES 245
            C +S
Sbjct: 358 TCSKS 362


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score =  103 bits (257), Expect = 7e-22
 Identities = 55/186 (29%), Positives = 86/186 (46%), Gaps = 9/186 (4%)

Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
           C  CG  +  G   +       G  WH  CF+C  C + L    +    G  +C   +  
Sbjct: 101 CSACGETVMPGSRKLEYG----GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYEN 156

Query: 186 LLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFES 245
              PRC+ C + +     T  + + WH +   C  C+T L GQ++  +D  P+C  CF  
Sbjct: 157 KFAPRCARCSKTLTQGGVTYRD-QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215

Query: 246 LYAEYCETCGEHI-GVDHAQ-MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
           L+A  C +C   I G+   + ++++ +HWH    CFSCA+C  SL+G  F+P   Q+ C 
Sbjct: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWH--HNCFSCARCSTSLVGQGFVPDGDQVLCQ 273

Query: 304 KTCSLG 309
                G
Sbjct: 274 GCSQAG 279



 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 45/153 (29%), Positives = 65/153 (42%), Gaps = 5/153 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF-ADECTEAEGR 209
           +H  CF C  C   L D  +  QD ++ C   +      +CSAC E +       E  G+
Sbjct: 61  FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120

Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
            WH   F C  CE  LG + ++   G  +C  C+E+ +A  C  C + +      +TY  
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTL--TQGGVTYRD 178

Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           Q WH    C  C  C+  L G  F  +    YC
Sbjct: 179 QPWH--RECLVCTGCQTPLAGQQFTSRDEDPYC 209



 Score = 83.2 bits (204), Expect = 9e-16
 Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 3/148 (2%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA-EGRHWHMK 214
           F C  CNE L    Y   D   +C   +       C+ C ++I  D      E RH+H  
Sbjct: 5   FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
            F C  C+  L  + +  +D    C  C+ S ++  C  CGE +     ++ Y GQ WH 
Sbjct: 65  CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWH- 123

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
            E CF C+ C+  L    F+P +G  YC
Sbjct: 124 -EHCFLCSGCEQPLGSRSFVPDKGAHYC 150



 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 2/88 (2%)

Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
           F C +C   L G++YI  D  P+C  C+++ +A  C  C + IG D  ++ Y+ +H+H  
Sbjct: 5   FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH-- 62

Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCS 303
           E CF C +C+ SL   PF  +  ++ C+
Sbjct: 63  EGCFRCCRCQRSLADEPFTCQDSELLCN 90


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 56/178 (31%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 125 VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHA 184
           +C  C   I G  V         G  WHP  FVC  C+  L    +F +DG   C   + 
Sbjct: 227 LCGSCNKPIAGQVVTAL------GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYF 280

Query: 185 ELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
           E   PRC  C++ I   +   A G HWH +HFCC+ C    G + +  ++GRP+C   F 
Sbjct: 281 ERFSPRCGFCNQPI-RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 339

Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
            L+A  C+ C   I  ++         WH    CF C +C A   G  F   +G+  C
Sbjct: 340 QLFAPRCQGCQGPILDNYISAL--SALWHPD--CFVCRECFAPFSGGSFFEHEGRPLC 393



 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 47/155 (30%), Positives = 65/155 (41%), Gaps = 5/155 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WHP  F C +C E   D  +  ++G+ +C R   +L  PRC  C   I  D    A 
Sbjct: 303 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL-DNYISAL 361

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTY 267
              WH   F C EC     G  +   +GRP C   F +     C TCG  + V    ++ 
Sbjct: 362 SALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG--LPVTGRCVSA 419

Query: 268 DGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
            G+ +H     F+C  C   L    F  + G+ YC
Sbjct: 420 LGRRFHPDH--FTCTFCLRPLTKGSFQERAGKPYC 452



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 41/117 (35%), Positives = 56/117 (47%), Gaps = 5/117 (4%)

Query: 188 KPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
           K  C +C++ I A +   A GR WH +HF C  C T LGG  +  KDG PFC  C+   +
Sbjct: 225 KGLCGSCNKPI-AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 283

Query: 248 AEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
           +  C  C + I   H  +T  G HWH    C  C  C        F  ++G+ YC +
Sbjct: 284 SPRCGFCNQPI--RHKMVTALGTHWHPEHFC--CVSCGEPFGDEGFHEREGRPYCRR 336



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 1/97 (1%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
           WHP CFVC  C        +F  +G+  C  H        C+ C  +     C  A GR 
Sbjct: 365 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGRR 423

Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
           +H  HF C  C   L    +  + G+P+C  CF  L+
Sbjct: 424 FHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 56/178 (31%), Positives = 78/178 (43%), Gaps = 11/178 (6%)

Query: 125 VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHA 184
           +C  C   I G  V         G  WHP  FVC  C+  L    +F +DG   C   + 
Sbjct: 210 LCGSCNKPIAGQVVTAL------GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYF 263

Query: 185 ELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
           E   PRC  C++ I   +   A G HWH +HFCC+ C    G + +  ++GRP+C   F 
Sbjct: 264 ERFSPRCGFCNQPI-RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFL 322

Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
            L+A  C+ C   I  ++         WH    CF C +C A   G  F   +G+  C
Sbjct: 323 QLFAPRCQGCQGPILDNYISAL--SALWHPD--CFVCRECFAPFSGGSFFEHEGRPLC 376



 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 47/155 (30%), Positives = 65/155 (41%), Gaps = 5/155 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WHP  F C +C E   D  +  ++G+ +C R   +L  PRC  C   I  D    A 
Sbjct: 286 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL-DNYISAL 344

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTY 267
              WH   F C EC     G  +   +GRP C   F +     C TCG  + V    ++ 
Sbjct: 345 SALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG--LPVTGRCVSA 402

Query: 268 DGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
            G+ +H     F+C  C   L    F  + G+ YC
Sbjct: 403 LGRRFHPDH--FTCTFCLRPLTKGSFQERAGKPYC 435



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 41/117 (35%), Positives = 56/117 (47%), Gaps = 5/117 (4%)

Query: 188 KPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
           K  C +C++ I A +   A GR WH +HF C  C T LGG  +  KDG PFC  C+   +
Sbjct: 208 KGLCGSCNKPI-AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERF 266

Query: 248 AEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
           +  C  C + I   H  +T  G HWH    C  C  C        F  ++G+ YC +
Sbjct: 267 SPRCGFCNQPI--RHKMVTALGTHWHPEHFC--CVSCGEPFGDEGFHEREGRPYCRR 319



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 1/97 (1%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
           WHP CFVC  C        +F  +G+  C  H        C+ C  +     C  A GR 
Sbjct: 348 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGRR 406

Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
           +H  HF C  C   L    +  + G+P+C  CF  L+
Sbjct: 407 FHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 56/199 (28%), Positives = 84/199 (42%), Gaps = 12/199 (6%)

Query: 109 LGRGTIKLLSRAVMHA---VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELL 165
           L RGT++   R    +   +C  C   I G  +         G  WHP  F C  C   L
Sbjct: 421 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAM------GRSWHPEEFTCAYCKTSL 474

Query: 166 VDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVL 225
            D+ +  +   ++C R + +   P C+ C+  I   E   A  + WH   F C  C+   
Sbjct: 475 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPF 533

Query: 226 GGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCK 285
           G   + M+DG P+C   + +L++  C  C   +      +   G  WH T  CF CA C 
Sbjct: 534 GNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT--CFICAVCH 591

Query: 286 ASLLGCPFLPKQGQIYCSK 304
            +L G PF  K+ +  C K
Sbjct: 592 VNLEGQPFYSKKDRPLCKK 610



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 14/57 (24%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRH 182
           C  C   +  G+  + A     G  WH +CF+C  C+  L    ++ +  +  C +H
Sbjct: 559 CHGCDFPVEAGDKFIEAL----GHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 611


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 56/199 (28%), Positives = 84/199 (42%), Gaps = 12/199 (6%)

Query: 109 LGRGTIKLLSRAVMHA---VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELL 165
           L RGT++   R    +   +C  C   I G  +         G  WHP  F C  C   L
Sbjct: 531 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAM------GRSWHPEEFTCAYCKTSL 584

Query: 166 VDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVL 225
            D+ +  +   ++C R + +   P C+ C+  I   E   A  + WH   F C  C+   
Sbjct: 585 ADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPF 643

Query: 226 GGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCK 285
           G   + M+DG P+C   + +L++  C  C   +      +   G  WH T  CF CA C 
Sbjct: 644 GNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT--CFICAVCH 701

Query: 286 ASLLGCPFLPKQGQIYCSK 304
            +L G PF  K+ +  C K
Sbjct: 702 VNLEGQPFYSKKDRPLCKK 720



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 14/57 (24%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRH 182
           C  C   +  G+  + A     G  WH +CF+C  C+  L    ++ +  +  C +H
Sbjct: 669 CHGCDFPVEAGDKFIEAL----GHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKH 721


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
           WH +CF C  C   L +  +  +D KI C +       P+C  C + I A D+  E +G 
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
            WH   F C  C+ V+G   +  K    +C  C E+ +A++C  C +   +    +TY  
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178

Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           Q WHA   CF C  C   L G  F   + Q YC
Sbjct: 179 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209



 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH  CF C  C +++    +F +    +C   H       C  C++ I +   T  +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
            + WH   F C+ C   L GQR+   + + +C  C+++  A+ C  C   I   G   + 
Sbjct: 179 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237

Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           + Y+GQ WH  + CF C +C  +L    F+  Q Q+YC
Sbjct: 238 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
           F C  C   L G++Y+ KDG   C  CF+   A  C  C + IG D  ++ Y  + WH T
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
             CF CA+C   L    F+ K  +I C+K C+  ED
Sbjct: 65  --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
           F C  C + L    Y  +DG   C +   +     C  C + I AD      + R WH  
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
            F C +C   L  + ++ KD +  C  C     +  C+ C + I      + Y G  WH 
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
            + CF+C+ CK  +    F PK    YC
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
           WH  CFVC TC++ L    +   + + +C   +   +  +C+ C   I            
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240

Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
           EG+ WH   F C +C   L  +R++    + +C  C + L
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280


>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
          Length = 323

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
           WH +CF C  C   L +  +  +D KI C +       P+C  C + I A D+  E +G 
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
            WH   F C  C+ V+G   +  K    +C  C E+ +A++C  C +   +    +TY  
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178

Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           Q WHA   CF C  C   L G  F   + Q YC
Sbjct: 179 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
           F C  C   L G++Y+ KDG   C  CF+   A  C  C + IG D  ++ Y  + WH T
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
             CF CA+C   L    F+ K  +I C+K C+  ED
Sbjct: 65  --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
           F C  C + L    Y  +DG   C +   +     C  C + I AD      + R WH  
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
            F C +C   L  + ++ KD +  C  C     +  C+ C + I      + Y G  WH 
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
            + CF+C+ CK  +    F PK    YC
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 1/107 (0%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH  CF C  C +++    +F +    +C   H       C  C++ I +   T  +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETC 254
            + WH   F C+ C   L GQR+   + + +C  C+++  A+ C  C
Sbjct: 179 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
           WH +CF C  C   L +  +  +D KI C +       P+C  C + I A D+  E +G 
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
            WH   F C  C+ V+G   +  K    +C  C E+ +A++C  C +   +    +TY  
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178

Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           Q WHA   CF C  C   L G  F   + Q YC
Sbjct: 179 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209



 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH  CF C  C +++    +F +    +C   H       C  C++ I +   T  +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
            + WH   F C+ C   L GQR+   + + +C  C+++  A+ C  C   I   G   + 
Sbjct: 179 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237

Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           + Y+GQ WH  + CF C +C  +L    F+  Q Q+YC
Sbjct: 238 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
           F C  C   L G++Y+ KDG   C  CF+   A  C  C + IG D  ++ Y  + WH T
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
             CF CA+C   L    F+ K  +I C+K C+  ED
Sbjct: 65  --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
           F C  C + L    Y  +DG   C +   +     C  C + I AD      + R WH  
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
            F C +C   L  + ++ KD +  C  C     +  C+ C + I      + Y G  WH 
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
            + CF+C+ CK  +    F PK    YC
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
           WH  CFVC TC++ L    +   + + +C   +   +  +C+ C   I            
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240

Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
           EG+ WH   F C +C   L  +R++    + +C  C + L
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 57/188 (30%), Positives = 79/188 (42%), Gaps = 11/188 (5%)

Query: 115 KLLSRAVMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQD 174
           KL    V   VC  C   I G  V         G  WHP  FVC  C E +    +F +D
Sbjct: 180 KLGVATVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERD 233

Query: 175 GKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKD 234
           G+ +C + +  L  PRC  C+  I  D+   A  R WH +HF C +C    G + +  KD
Sbjct: 234 GQPYCEKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 292

Query: 235 GRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFL 294
           G+ +C   +  ++A  C  C   I  ++         WH    CF C +C    +   F 
Sbjct: 293 GKAYCRKDYFDMFAPKCGGCARAILENYISAL--NTLWH--PECFVCRECFTPFVNGSFF 348

Query: 295 PKQGQIYC 302
              GQ YC
Sbjct: 349 EHDGQPYC 356



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 5/121 (4%)

Query: 184 AELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCF 243
           A + K  C AC + I A +   A G+ WH +HF C  C+  +G + +  +DG+P+C   +
Sbjct: 184 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242

Query: 244 ESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
            +L++  C  C   I +D      D + WH     F CAQC A      F  K G+ YC 
Sbjct: 243 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 298

Query: 304 K 304
           K
Sbjct: 299 K 299



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
           WHP CFVC  C    V+  +F  DG+ +C  H+ E     CS C + I    C  A  + 
Sbjct: 328 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 386

Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
           +H +HF C  C   L    +  ++ +P+C  CF  L+
Sbjct: 387 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 5/152 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
           WHP  F C  C        +  +DGK +C + + ++  P+C  C   I  +    A    
Sbjct: 269 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 327

Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQ 270
           WH + F C EC T      +   DG+P+C   +       C  C + I      +T   +
Sbjct: 328 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRCITAMAK 385

Query: 271 HWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
            +H     F CA C   L    F  +  + YC
Sbjct: 386 KFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 415


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 57/188 (30%), Positives = 79/188 (42%), Gaps = 11/188 (5%)

Query: 115 KLLSRAVMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQD 174
           KL    V   VC  C   I G  V         G  WHP  FVC  C E +    +F +D
Sbjct: 313 KLGVATVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERD 366

Query: 175 GKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKD 234
           G+ +C + +  L  PRC  C+  I  D+   A  R WH +HF C +C    G + +  KD
Sbjct: 367 GQPYCEKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 425

Query: 235 GRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFL 294
           G+ +C   +  ++A  C  C   I  ++         WH    CF C +C    +   F 
Sbjct: 426 GKAYCRKDYFDMFAPKCGGCARAILENYISAL--NTLWH--PECFVCRECFTPFVNGSFF 481

Query: 295 PKQGQIYC 302
              GQ YC
Sbjct: 482 EHDGQPYC 489



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 5/121 (4%)

Query: 184 AELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCF 243
           A + K  C AC + I A +   A G+ WH +HF C  C+  +G + +  +DG+P+C   +
Sbjct: 317 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375

Query: 244 ESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
            +L++  C  C   I +D      D + WH     F CAQC A      F  K G+ YC 
Sbjct: 376 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 431

Query: 304 K 304
           K
Sbjct: 432 K 432



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
           WHP CFVC  C    V+  +F  DG+ +C  H+ E     CS C + I    C  A  + 
Sbjct: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 519

Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
           +H +HF C  C   L    +  ++ +P+C  CF  L+
Sbjct: 520 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 5/152 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
           WHP  F C  C        +  +DGK +C + + ++  P+C  C   I  +    A    
Sbjct: 402 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 460

Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQ 270
           WH + F C EC T      +   DG+P+C   +       C  C + I      +T   +
Sbjct: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRCITAMAK 518

Query: 271 HWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
            +H     F CA C   L    F  +  + YC
Sbjct: 519 KFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 548


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 57/188 (30%), Positives = 79/188 (42%), Gaps = 11/188 (5%)

Query: 115 KLLSRAVMHAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQD 174
           KL    V   VC  C   I G  V         G  WHP  FVC  C E +    +F +D
Sbjct: 347 KLGVATVAKGVCGACKKPIAGQVVTAM------GKTWHPEHFVCTHCQEEIGSRNFFERD 400

Query: 175 GKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKD 234
           G+ +C + +  L  PRC  C+  I  D+   A  R WH +HF C +C    G + +  KD
Sbjct: 401 GQPYCEKDYHNLFSPRCYYCNGPIL-DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKD 459

Query: 235 GRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFL 294
           G+ +C   +  ++A  C  C   I  ++         WH    CF C +C    +   F 
Sbjct: 460 GKAYCRKDYFDMFAPKCGGCARAILENYISAL--NTLWH--PECFVCRECFTPFVNGSFF 515

Query: 295 PKQGQIYC 302
              GQ YC
Sbjct: 516 EHDGQPYC 523



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 5/121 (4%)

Query: 184 AELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCF 243
           A + K  C AC + I A +   A G+ WH +HF C  C+  +G + +  +DG+P+C   +
Sbjct: 351 ATVAKGVCGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 409

Query: 244 ESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
            +L++  C  C   I +D      D + WH     F CAQC A      F  K G+ YC 
Sbjct: 410 HNLFSPRCYYCNGPI-LDKVVTALD-RTWHPEH--FFCAQCGAFFGPEGFHEKDGKAYCR 465

Query: 304 K 304
           K
Sbjct: 466 K 466



 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
           WHP CFVC  C    V+  +F  DG+ +C  H+ E     CS C + I    C  A  + 
Sbjct: 495 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 553

Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLY 247
           +H +HF C  C   L    +  ++ +P+C  CF  L+
Sbjct: 554 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 5/152 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRH 210
           WHP  F C  C        +  +DGK +C + + ++  P+C  C   I  +    A    
Sbjct: 436 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL-ENYISALNTL 494

Query: 211 WHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQ 270
           WH + F C EC T      +   DG+P+C   +       C  C + I      +T   +
Sbjct: 495 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI--TGRCITAMAK 552

Query: 271 HWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
            +H     F CA C   L    F  +  + YC
Sbjct: 553 KFHPEH--FVCAFCLKQLNKGTFKEQNDKPYC 582


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
           WH +CF C  C   L +  +  +D KI C +       P+C  C + I A D+  E +G 
Sbjct: 90  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149

Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
            WH   F C  C+ V+G   +  K    +C  C E+ +A++C  C +   +    +TY  
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 207

Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           Q WHA   CF C  C   L G  F   + Q YC
Sbjct: 208 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 238



 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH  CF C  C +++    +F +    +C   H       C  C++ I +   T  +
Sbjct: 148 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 207

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
            + WH   F C+ C   L GQR+   + + +C  C+++  A+ C  C   I   G   + 
Sbjct: 208 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 266

Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           + Y+GQ WH  + CF C +C  +L    F+  Q Q+YC
Sbjct: 267 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 302



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
           F C  C   L G++Y+ KDG   C  CF+   A  C  C + IG D  ++ Y  + WH T
Sbjct: 34  FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93

Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
             CF CA+C   L    F+ K  +I C+K C+  ED
Sbjct: 94  --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 126



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
           F C  C + L    Y  +DG   C +   +     C  C + I AD      + R WH  
Sbjct: 34  FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
            F C +C   L  + ++ KD +  C  C     +  C+ C + I      + Y G  WH 
Sbjct: 94  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 152

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
            + CF+C+ CK  +    F PK    YC
Sbjct: 153 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 179



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
           WH  CFVC TC++ L    +   + + +C   +   +  +C+ C   I            
Sbjct: 210 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 269

Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
           EG+ WH   F C +C   L  +R++    + +C  C + L
Sbjct: 270 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 309


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
           WH +CF C  C   L +  +  +D KI C +       P+C  C + I A D+  E +G 
Sbjct: 77  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136

Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
            WH   F C  C+ V+G   +  K    +C  C E+ +A++C  C +   +    +TY  
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 194

Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           Q WHA   CF C  C   L G  F   + Q YC
Sbjct: 195 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 225



 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH  CF C  C +++    +F +    +C   H       C  C++ I +   T  +
Sbjct: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
            + WH   F C+ C   L GQR+   + + +C  C+++  A+ C  C   I   G   + 
Sbjct: 195 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 253

Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           + Y+GQ WH  + CF C +C  +L    F+  Q Q+YC
Sbjct: 254 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 289



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
           F C  C   L G++Y+ KDG   C  CF+   A  C  C + IG D  ++ Y  + WH T
Sbjct: 21  FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80

Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
             CF CA+C   L    F+ K  +I C+K C+  ED
Sbjct: 81  --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 113



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
           F C  C + L    Y  +DG   C +   +     C  C + I AD      + R WH  
Sbjct: 21  FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
            F C +C   L  + ++ KD +  C  C     +  C+ C + I      + Y G  WH 
Sbjct: 81  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 139

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
            + CF+C+ CK  +    F PK    YC
Sbjct: 140 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 166



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
           WH  CFVC TC++ L    +   + + +C   +   +  +C+ C   I            
Sbjct: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256

Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
           EG+ WH   F C +C   L  +R++    + +C  C + L
Sbjct: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 5/153 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA-DECTEAEGR 209
           WH +CF C  C   L +  +  +D KI C +       P+C  C + I A D+  E +G 
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
            WH   F C  C+ V+G   +  K    +C  C E+ +A++C  C +   +    +TY  
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178

Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           Q WHA   CF C  C   L G  F   + Q YC
Sbjct: 179 QPWHAD--CFVCVTCSKKLAGQRFTAVEDQYYC 209



 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 6/158 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH  CF C  C +++    +F +    +C   H       C  C++ I +   T  +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI---GVDHAQ 264
            + WH   F C+ C   L GQR+   + + +C  C+++  A+ C  C   I   G   + 
Sbjct: 179 -QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237

Query: 265 MTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           + Y+GQ WH  + CF C +C  +L    F+  Q Q+YC
Sbjct: 238 VAYEGQSWH--DYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 3/96 (3%)

Query: 216 FCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHAT 275
           F C  C   L G++Y+ KDG   C  CF+   A  C  C + IG D  ++ Y  + WH T
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 276 EACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
             CF CA+C   L    F+ K  +I C+K C+  ED
Sbjct: 65  --CFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 3/148 (2%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADEC-TEAEGRHWHMK 214
           F C  C + L    Y  +DG   C +   +     C  C + I AD      + R WH  
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
            F C +C   L  + ++ KD +  C  C     +  C+ C + I      + Y G  WH 
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
            + CF+C+ CK  +    F PK    YC
Sbjct: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFA----DECTEA 206
           WH  CFVC TC++ L    +   + + +C   +   +  +C+ C   I            
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240

Query: 207 EGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESL 246
           EG+ WH   F C +C   L  +R++    + +C  C + L
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 93.6 bits (231), Expect = 7e-19
 Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 2/90 (2%)

Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
           + F C  C   L G++YI+++  P+C  CFE+L+A  CE CG+ IG D   ++Y  +HWH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
             EACF C+QC+ SL+  PF  K+ Q+ C+
Sbjct: 63  --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 9/178 (5%)

Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
           CE+CG  I G +    + +      WH +CF C  C   LVD  +  ++ ++ C   ++ 
Sbjct: 40  CEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSN 95

Query: 186 LLKPRCSACDEIIF-ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
               +C  C + I       E +G  WH   F C  C+  +G + +I KD + FC  C+E
Sbjct: 96  EYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYE 155

Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
             +A  C  C + I      +TY  Q WH  + CF C  C+  L G  F  +    YC
Sbjct: 156 KQHAMQCVQCKKPITT--GGVTYREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH +CF+C  C + +    +  +D +  C   + +    +C  C + I     T  E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
            + WH + F C  C   L GQR+  +D   +C  CF  LYA+ C  C   I G+   + +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237

Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           +++ + WH    CF+C +C  SL+G  FL ++  I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 5/149 (3%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA--EGRHWHM 213
           F C  CNE L    Y  ++   +C      L    C  C + I  D C +   + RHWH 
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCD-CKDLSYKDRHWHE 63

Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
             F C +C   L  + +  K+ +  C  C+ + Y+  C+ C + I     +M Y G  WH
Sbjct: 64  ACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWH 123

Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYC 302
             E CF C +C+  +    F+PK  Q +C
Sbjct: 124 --ETCFICHRCQQPIGTKSFIPKDNQNFC 150



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)

Query: 123 HAV-CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGR 181
           HA+ C QC   I  G V     R  P   WH  CFVC  C + L    +  +D   +C  
Sbjct: 158 HAMQCVQCKKPITTGGVTY---REQP---WHKECFVCTACRKQLSGQRFTARDDFAYCLN 211

Query: 182 HHAELLKPRCSACDEIIFADECTEA---EGRHWHMKHFCCLECETVLGGQRYIMKDGRPF 238
              +L   +C+ C   I     T+    E R WH   F C +C   L G+ ++ +     
Sbjct: 212 CFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDIL 271

Query: 239 CCGC 242
           C  C
Sbjct: 272 CPDC 275


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 93.6 bits (231), Expect = 7e-19
 Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 2/90 (2%)

Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
           + F C  C   L G++YI+++  P+C  CFE+L+A  CE CG+ IG D   ++Y  +HWH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
             EACF C+QC+ SL+  PF  K+ Q+ C+
Sbjct: 63  --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 9/178 (5%)

Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
           CE+CG  I G +    + +      WH +CF C  C   LVD  +  ++ ++ C   ++ 
Sbjct: 40  CEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSN 95

Query: 186 LLKPRCSACDEIIF-ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
               +C  C + I       E +G  WH   F C  C+  +G + +I KD + FC  C+E
Sbjct: 96  EYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYE 155

Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
             +A  C  C + I      +TY  Q WH  + CF C  C+  L G  F  +    YC
Sbjct: 156 KQHAMQCVQCKKPITT--GGVTYREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH +CF+C  C + +    +  +D +  C   + +    +C  C + I     T  E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
            + WH + F C  C   L GQR+  +D   +C  CF  LYA+ C  C   I G+   + +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237

Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           +++ + WH    CF+C +C  SL+G  FL ++  I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 5/149 (3%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA--EGRHWHM 213
           F C  CNE L    Y  ++   +C      L    C  C + I  D C +   + RHWH 
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCD-CKDLSYKDRHWHE 63

Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
             F C +C   L  + +  K+ +  C  C+ + Y+  C+ C + I     +M Y G  WH
Sbjct: 64  ACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWH 123

Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYC 302
             E CF C +C+  +    F+PK  Q +C
Sbjct: 124 --ETCFICHRCQQPIGTKSFIPKDNQNFC 150



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)

Query: 123 HAV-CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGR 181
           HA+ C QC   I  G V     R  P   WH  CFVC  C + L    +  +D   +C  
Sbjct: 158 HAMQCVQCKKPITTGGVTY---REQP---WHKECFVCTACRKQLSGQRFTARDDFAYCLN 211

Query: 182 HHAELLKPRCSACDEIIFADECTEA---EGRHWHMKHFCCLECETVLGGQRYIMKDGRPF 238
              +L   +C+ C   I     T+    E R WH   F C +C   L G+ ++ +     
Sbjct: 212 CFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDIL 271

Query: 239 CCGC 242
           C  C
Sbjct: 272 CPDC 275


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 93.6 bits (231), Expect = 7e-19
 Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 2/90 (2%)

Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
           + F C  C   L G++YI+++  P+C  CFE+L+A  CE CG+ IG D   ++Y  +HWH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
             EACF C+QC+ SL+  PF  K+ Q+ C+
Sbjct: 63  --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 9/178 (5%)

Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
           CE+CG  I G +    + +      WH +CF C  C   LVD  +  ++ ++ C   ++ 
Sbjct: 40  CEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSN 95

Query: 186 LLKPRCSACDEIIF-ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
               +C  C + I       E +G  WH   F C  C+  +G + +I KD + FC  C+E
Sbjct: 96  EYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYE 155

Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
             +A  C  C + I      +TY  Q WH  + CF C  C+  L G  F  +    YC
Sbjct: 156 KQHAMQCVQCKKPITT--GGVTYREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH +CF+C  C + +    +  +D +  C   + +    +C  C + I     T  E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
            + WH + F C  C   L GQR+  +D   +C  CF  LYA+ C  C   I G+   + +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237

Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           +++ + WH    CF+C +C  SL+G  FL ++  I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 5/149 (3%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA--EGRHWHM 213
           F C  CNE L    Y  ++   +C      L    C  C + I  D C +   + RHWH 
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCD-CKDLSYKDRHWHE 63

Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
             F C +C   L  + +  K+ +  C  C+ + Y+  C+ C + I     +M Y G  WH
Sbjct: 64  ACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWH 123

Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYC 302
             E CF C +C+  +    F+PK  Q +C
Sbjct: 124 --ETCFICHRCQQPIGTKSFIPKDNQNFC 150



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)

Query: 123 HAV-CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGR 181
           HA+ C QC   I  G V     R  P   WH  CFVC  C + L    +  +D   +C  
Sbjct: 158 HAMQCVQCKKPITTGGVTY---REQP---WHKECFVCTACRKQLSGQRFTARDDFAYCLN 211

Query: 182 HHAELLKPRCSACDEIIFADECTEA---EGRHWHMKHFCCLECETVLGGQRYIMKDGRPF 238
              +L   +C+ C   I     T+    E R WH   F C +C   L G+ ++ +     
Sbjct: 212 CFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDIL 271

Query: 239 CCGC 242
           C  C
Sbjct: 272 CPDC 275


>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 93.6 bits (231), Expect = 7e-19
 Identities = 39/90 (43%), Positives = 58/90 (64%), Gaps = 2/90 (2%)

Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
           + F C  C   L G++YI+++  P+C  CFE+L+A  CE CG+ IG D   ++Y  +HWH
Sbjct: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62

Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYCS 303
             EACF C+QC+ SL+  PF  K+ Q+ C+
Sbjct: 63  --EACFHCSQCRNSLVDKPFAAKEDQLLCT 90



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 9/178 (5%)

Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAE 185
           CE+CG  I G +    + +      WH +CF C  C   LVD  +  ++ ++ C   ++ 
Sbjct: 40  CEECGKPI-GCDCKDLSYKDRH---WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSN 95

Query: 186 LLKPRCSACDEIIF-ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
               +C  C + I       E +G  WH   F C  C+  +G + +I KD + FC  C+E
Sbjct: 96  EYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYE 155

Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
             +A  C  C + I      +TY  Q WH  + CF C  C+  L G  F  +    YC
Sbjct: 156 KQHAMQCVQCKKPITT--GGVTYREQPWH--KECFVCTACRKQLSGQRFTARDDFAYC 209



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 47/157 (29%), Positives = 76/157 (48%), Gaps = 5/157 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH +CF+C  C + +    +  +D +  C   + +    +C  C + I     T  E
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
            + WH + F C  C   L GQR+  +D   +C  CF  LYA+ C  C   I G+   + +
Sbjct: 179 -QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYI 237

Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           +++ + WH    CF+C +C  SL+G  FL ++  I C
Sbjct: 238 SFEERQWH--NDCFNCKKCSLSLVGRGFLTERDDILC 272



 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 44/149 (29%), Positives = 66/149 (44%), Gaps = 5/149 (3%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA--EGRHWHM 213
           F C  CNE L    Y  ++   +C      L    C  C + I  D C +   + RHWH 
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCD-CKDLSYKDRHWHE 63

Query: 214 KHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWH 273
             F C +C   L  + +  K+ +  C  C+ + Y+  C+ C + I     +M Y G  WH
Sbjct: 64  ACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWH 123

Query: 274 ATEACFSCAQCKASLLGCPFLPKQGQIYC 302
             E CF C +C+  +    F+PK  Q +C
Sbjct: 124 --ETCFICHRCQQPIGTKSFIPKDNQNFC 150



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 36/124 (29%), Positives = 50/124 (40%), Gaps = 10/124 (8%)

Query: 123 HAV-CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGR 181
           HA+ C QC   I  G V     R  P   WH  CFVC  C + L    +  +D   +C  
Sbjct: 158 HAMQCVQCKKPITTGGVTY---REQP---WHKECFVCTACRKQLSGQRFTARDDFAYCLN 211

Query: 182 HHAELLKPRCSACDEIIFADECTEA---EGRHWHMKHFCCLECETVLGGQRYIMKDGRPF 238
              +L   +C+ C   I     T+    E R WH   F C +C   L G+ ++ +     
Sbjct: 212 CFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDIL 271

Query: 239 CCGC 242
           C  C
Sbjct: 272 CPDC 275


>gi|30410801 activator of cAMP-responsive element modulator (CREM)
           in testis [Homo sapiens]
          Length = 284

 Score = 90.1 bits (222), Expect = 8e-18
 Identities = 49/166 (29%), Positives = 81/166 (48%), Gaps = 6/166 (3%)

Query: 148 GVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAE 207
           G  WH +CFVC  C + +       ++   +C     +     C+ C ++I +   T  +
Sbjct: 120 GNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCD 179

Query: 208 GRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHI-GVDHAQ-M 265
            + WH + F C  C   L  ++++ +D  PFC  C+  LYA  C  C + I G+  A+ +
Sbjct: 180 -QLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFI 238

Query: 266 TYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGED 311
            +    WH+   CF+C +C  SL+G  FL +  +I+C K C  G D
Sbjct: 239 CFQDSQWHS--ECFNCGKCSVSLVGKGFLTQNKEIFCQK-CGSGMD 281



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 44/153 (28%), Positives = 68/153 (44%), Gaps = 5/153 (3%)

Query: 151 WHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF-ADECTEAEGR 209
           WH  CF C  CN  LV+  +  +D ++ C   ++     +C  C   I       E +G 
Sbjct: 62  WHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGN 121

Query: 210 HWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDG 269
           +WH   F C  C   +G +  I K+   +C  CFE  +A YC  C + I      +T+  
Sbjct: 122 YWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI--TSGGITFCD 179

Query: 270 QHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
           Q WH  + CF C+ C+  L    F+ +    +C
Sbjct: 180 QLWH--KECFLCSGCRKDLCEEQFMSRDDYPFC 210



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 15/149 (10%)

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
           HF C  C   L G++Y++KD  P+C  C++ +++ YCE C + I  D   + Y  +HWH 
Sbjct: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWH- 63

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGEDVHASDSSDSAFQSARS--RDSRR 332
            E CF C +C  SL+  PF  K  ++ C+       + ++++ S   F   R+    SR+
Sbjct: 64  -EGCFKCTKCNHSLVEKPFAAKDERLLCT-------ECYSNECSSKCFHCKRTIMPGSRK 115

Query: 333 SVRMG----KSSRSADQCRQSLLLSPALN 357
               G    ++    + CRQ +   P ++
Sbjct: 116 MEFKGNYWHETCFVCENCRQPIGTKPLIS 144



 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 40/148 (27%), Positives = 61/148 (41%), Gaps = 3/148 (2%)

Query: 156 FVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEA-EGRHWHMK 214
           F C  C   L+   Y  +D   +C   +  +    C  C + I +D      + RHWH  
Sbjct: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65

Query: 215 HFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHA 274
            F C +C   L  + +  KD R  C  C+ +  +  C  C   I     +M + G +WH 
Sbjct: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH- 124

Query: 275 TEACFSCAQCKASLLGCPFLPKQGQIYC 302
            E CF C  C+  +   P + K+   YC
Sbjct: 125 -ETCFVCENCRQPIGTKPLISKESGNYC 151


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 52/178 (29%), Positives = 78/178 (43%), Gaps = 9/178 (5%)

Query: 125 VCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHA 184
           VC QC   I G  +         G  +HP  FVC  C ++L +  +F + G I C   + 
Sbjct: 247 VCHQCHKVIRGRYLVAL------GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYD 300

Query: 185 ELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFE 244
               P C+ C + I   E   A    WH+  F C  C+T +  + + M++G P+C   +E
Sbjct: 301 VRYAPSCAKCKKKI-TGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYE 359

Query: 245 SLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYC 302
            ++   C  C   I      +   G  WH T  CF CA C+ +L G  F  K+ +  C
Sbjct: 360 KMFGTKCHGCDFKIDAGDRFLEALGFSWHDT--CFVCAICQINLEGKTFYSKKDRPLC 415



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 11/119 (9%)

Query: 189 PRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYA 248
           P C  C ++I       A G  +H + F C +C  VL    +  + G  FC  C++  YA
Sbjct: 246 PVCHQCHKVI-RGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304

Query: 249 EYCETCGEHIG--VDHA-QMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
             C  C + I   + HA +MT     WH    CF+CA CK  +    F  ++G  YC +
Sbjct: 305 PSCAKCKKKITGEIMHALKMT-----WHVH--CFTCAACKTPIRNRAFYMEEGVPYCER 356



 Score = 33.5 bits (75), Expect = 0.83
 Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 126 CEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRH 182
           C  C  KI+ G+  + A     G  WH +CFVC  C   L    ++ +  +  C  H
Sbjct: 366 CHGCDFKIDAGDRFLEAL----GFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 418


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,844,293
Number of Sequences: 37866
Number of extensions: 1803108
Number of successful extensions: 7708
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 192
Number of HSP's that attempted gapping in prelim test: 6701
Number of HSP's gapped (non-prelim): 749
length of query: 831
length of database: 18,247,518
effective HSP length: 111
effective length of query: 720
effective length of database: 14,044,392
effective search space: 10111962240
effective search space used: 10111962240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press