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Search of human proteins with 221625538
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]
(984 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens] 1954 0.0
gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens] 491 e-138
gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens] 199 1e-50
gi|145553976 zinc finger, CW type with coiled-coil domain 2 isof... 162 1e-39
gi|145553971 zinc finger, CW type with coiled-coil domain 2 isof... 162 1e-39
gi|38044112 restin isoform b [Homo sapiens] 45 3e-04
gi|4506751 restin isoform a [Homo sapiens] 45 3e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 42 0.002
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 42 0.002
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 42 0.002
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 42 0.002
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 42 0.002
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 42 0.002
gi|32698688 citron [Homo sapiens] 42 0.004
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 42 0.004
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 41 0.006
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 41 0.006
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 40 0.008
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens] 40 0.014
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 39 0.018
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 39 0.018
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 39 0.024
gi|197245440 hypothetical protein LOC23285 [Homo sapiens] 39 0.024
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 39 0.031
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 39 0.031
gi|52426743 cisplatin resistance-associated overexpressed protei... 39 0.031
gi|19923485 cisplatin resistance-associated overexpressed protei... 39 0.031
gi|118498362 kinectin 1 isoform b [Homo sapiens] 38 0.053
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 38 0.053
gi|42794779 myosin 18A isoform b [Homo sapiens] 38 0.053
>gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]
Length = 984
Score = 1954 bits (5063), Expect = 0.0
Identities = 984/984 (100%), Positives = 984/984 (100%)
Query: 1 MDDRYPALQRAQLRLDFIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGG 60
MDDRYPALQRAQLRLDFIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGG
Sbjct: 1 MDDRYPALQRAQLRLDFIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGG 60
Query: 61 FMLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKFIGQYGNGLKSGSMRIGKDFILFTKK 120
FMLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKFIGQYGNGLKSGSMRIGKDFILFTKK
Sbjct: 61 FMLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKFIGQYGNGLKSGSMRIGKDFILFTKK 120
Query: 121 EETMTCVFFSQTFCEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTE 180
EETMTCVFFSQTFCEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTE
Sbjct: 121 EETMTCVFFSQTFCEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTE 180
Query: 181 AELMQQFDVIYGKCGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGALEDFPARWSFRAY 240
AELMQQFDVIYGKCGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGALEDFPARWSFRAY
Sbjct: 181 AELMQQFDVIYGKCGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGALEDFPARWSFRAY 240
Query: 241 TSVLYFNPWMRIFIQAKRVKTKHLCYCLYRPRKYLYVTSSFKGAFKDEVKKAEEAVKIAE 300
TSVLYFNPWMRIFIQAKRVKTKHLCYCLYRPRKYLYVTSSFKGAFKDEVKKAEEAVKIAE
Sbjct: 241 TSVLYFNPWMRIFIQAKRVKTKHLCYCLYRPRKYLYVTSSFKGAFKDEVKKAEEAVKIAE 300
Query: 301 SILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAKQKNLKEKQRELKTARTLSLFYGVNV 360
SILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAKQKNLKEKQRELKTARTLSLFYGVNV
Sbjct: 301 SILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAKQKNLKEKQRELKTARTLSLFYGVNV 360
Query: 361 ENRSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNV 420
ENRSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNV
Sbjct: 361 ENRSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNV 420
Query: 421 QEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGI 480
QEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGI
Sbjct: 421 QEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGI 480
Query: 481 PFIIQCDLCLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVECLPSIPLGTMSTI 540
PFIIQCDLCLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVECLPSIPLGTMSTI
Sbjct: 481 PFIIQCDLCLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVECLPSIPLGTMSTI 540
Query: 541 SPSKNEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLL 600
SPSKNEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLL
Sbjct: 541 SPSKNEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLL 600
Query: 601 GDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRIPVAL 660
GDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRIPVAL
Sbjct: 601 GDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRIPVAL 660
Query: 661 PENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDE 720
PENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDE
Sbjct: 661 PENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDE 720
Query: 721 NTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKRSSSLPSWKSLLNVP 780
NTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKRSSSLPSWKSLLNVP
Sbjct: 721 NTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKRSSSLPSWKSLLNVP 780
Query: 781 MEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPS 840
MEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPS
Sbjct: 781 MEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPS 840
Query: 841 ELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNE 900
ELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNE
Sbjct: 841 ELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNE 900
Query: 901 ISLGQCENKRKISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQN 960
ISLGQCENKRKISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQN
Sbjct: 901 ISLGQCENKRKISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQN 960
Query: 961 NLNKVTIDARHRLPLEKNEKTSEN 984
NLNKVTIDARHRLPLEKNEKTSEN
Sbjct: 961 NLNKVTIDARHRLPLEKNEKTSEN 984
>gi|7662340 MORC family CW-type zinc finger 2 [Homo sapiens]
Length = 970
Score = 491 bits (1263), Expect = e-138
Identities = 257/518 (49%), Positives = 343/518 (66%), Gaps = 14/518 (2%)
Query: 62 MLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKFIGQYGNGLKSGSMRIGKDFILFTKKE 121
MLCFLDDG GM P +A+ +I FG+S KR IGQYGNGLKSGSMRIGKDFILFTKKE
Sbjct: 1 MLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKE 60
Query: 122 ETMTCVFFSQTFCEEESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEA 181
+TMTC+F S+TF EEE + EV+VP+P+W RTRE VTD+ +KFA+E +IYKYSPF+TE
Sbjct: 61 DTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEE 120
Query: 182 ELMQQFDVIYGKCGTLLVIYNLKLLLNGEPELDVKTDKEDILMAGALED--FPARWSFRA 239
E+M QF I G GTL++I+NLKL+ NGEPELD+ ++ DI MA + P R SFRA
Sbjct: 121 EVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRA 180
Query: 240 YTSVLYFNPWMRIFIQAKRVKTKHLCYCLYRPRKYLYVTSSFKGAFKDEVKKAEEAVKIA 299
Y +VLY +P MRIFI +V+TK L CLY+PR Y Y +S FK + EVKKAE +IA
Sbjct: 181 YAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIA 240
Query: 300 ESILKEAQIKVNQCD--------RTSLSSAKDVLQRAL---EDVEAKQKNLKEKQRELKT 348
E +EA+ K + R S + V RA+ + + K++ + KQR LK
Sbjct: 241 EEKAREAESKARTLEVRLGGDLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKE 300
Query: 349 ARTLSLFYGVNVENRSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEVM 408
+ L+ +GVN+E+R GMFIY+ +RLIKM+EKVG QL+ G GVVG+V++P V+
Sbjct: 301 PKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACG-GVVGVVDVPYLVL 359
Query: 409 EPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPLN 468
EP+HNKQ+F + +EY HLL+ MG++L QY KD I R + F +EFGY + + P +
Sbjct: 360 EPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSS 419
Query: 469 SFQYQRRQAMGIPFIIQCDLCLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVEC 528
+Y+RR+AM IP IQCDLCLKWR LP + EK++ D W+C+ NP+ ++ C E
Sbjct: 420 ELRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQ 479
Query: 529 LPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQ 566
+PLGT ++ EK+KQL E + + Q +L Q
Sbjct: 480 KQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQ 517
Score = 44.3 bits (103), Expect = 6e-04
Identities = 43/161 (26%), Positives = 73/161 (45%), Gaps = 15/161 (9%)
Query: 791 IARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPSELEEPALSCE 850
+A S S ++ P ++ + ET+ L LR L YF P S+ + A++ +
Sbjct: 821 VAEPSTSECLRI--EPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSD 878
Query: 851 LEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNEISLGQCENKR 910
E ++ LK Y QYE ++ S +++R +E SL E K
Sbjct: 879 -----ELISFPLK--------EYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKL 925
Query: 911 KISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALL 951
+ +E+KL+ LR + LLQK+Q ++ D Y+E L+
Sbjct: 926 RETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLI 966
>gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]
Length = 939
Score = 199 bits (505), Expect = 1e-50
Identities = 177/683 (25%), Positives = 288/683 (42%), Gaps = 140/683 (20%)
Query: 17 FIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE 76
F+H NST+H++ F A+AEL+DNA D ++ +D + L F D+G GM+ ++
Sbjct: 18 FLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIW-IDKTVINDHICLTFTDNGNGMTSDK 76
Query: 77 ASDIIYFGRSKK-RLSTLKFIGQYGNGLKSGSMRIGKDFILFTKKEETMTCVFFSQTFCE 135
++ FG S K ++ +G YGNG KSGSMR+GKD I+FTK E+M+ SQT+ E
Sbjct: 77 LHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLE 136
Query: 136 EESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGKCG 195
VVVP+ ++ + R+ + K + L+ I ++S F TE +L+ + D I GK G
Sbjct: 137 VIKAEHVVVPIVAFN-KHRQMINLAESKAS--LAAILEHSLFSTEQKLLAELDAIIGKKG 193
Query: 196 TLLVIYNLKLLLNGEPELDVKTDKEDILMAGALEDFPARWSFRAYTSVLYFNPWMRIFIQ 255
T ++I+NL+ N E D + DK DI + L++ + ++ + P ++
Sbjct: 194 TRIIIWNLRSYKNAT-EFDFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLR 252
Query: 256 AKRVKTKHLCYCLY-RPRKYLYVTSSFKGAFKDEVKKAEEAVKIAESILKEAQIKVNQCD 314
A C LY +PR + IL+ ++K
Sbjct: 253 A-------YCSILYLKPRMQI--------------------------ILRGQKVKTQLVS 279
Query: 315 RTSLSSAKDVLQRALEDVEAKQKNLKEKQRELKTARTLSLFYGVNVENRSQAGMFIYSNN 374
++ +DV R ++T+ + +G N N+ G+ +Y N
Sbjct: 280 KSLAYIERDVY------------------RPKFLSKTVRITFGFNCRNKDHYGIMMYHRN 321
Query: 375 RLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYL 434
RLIK +EKVG QL+ + +G GVVGI I ++P+HNKQ+F EY + +G+ L
Sbjct: 322 RLIKAYEKVGCQLRANN-MGVGVVGI--IECNFLKPTHNKQDFDYTNEYRLTITALGEKL 378
Query: 435 VQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGIPFIIQCDLCLKWRV 494
Y + + + + P+ Q + Q +QCD CLKWR
Sbjct: 379 NDYWNEMKVKK------------NTEYPLNLPVEDIQKRPDQTW-----VQCDACLKWRK 421
Query: 495 LPSSTNYQEKEFFDIWICANNPNRLENSC------------------------------H 524
LP + ++ W C+NNP+ +C
Sbjct: 422 LPDGMDQLPEK----WYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIR 477
Query: 525 QVECLPSI---------PLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQPQPQFIPVD 575
Q E +P I L T S SP ++ + L E Y RL P +
Sbjct: 478 QPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPE 537
Query: 576 EITVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYI 635
++ T + N K +++ S FE S + ++ D DV +
Sbjct: 538 SNSLKRRLSTRSSILNAKNRRLS-----------SQFENSVYKG------DDDDEDVIIL 580
Query: 636 SETKIMKKSMEE--KMNSQQQRI 656
E K +++ M S+Q +
Sbjct: 581 EENSTPKPAVDHDIDMKSEQSHV 603
>gi|145553976 zinc finger, CW type with coiled-coil domain 2 isoform
a [Homo sapiens]
Length = 937
Score = 162 bits (410), Expect = 1e-39
Identities = 102/287 (35%), Positives = 160/287 (55%), Gaps = 25/287 (8%)
Query: 17 FIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE 76
++ +NS++H+ F A+AELLDNA D VF +D E+++ L F DDGCGM+P +
Sbjct: 39 YLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVF-IDVEEVKNKSCLTFTDDGCGMTPHK 97
Query: 77 ASDIIYFGRSKKRLSTLKF-IGQYGNGLKSGSMRIGKDFILFTKKEETMTCVFFSQTFCE 135
++ FG + K + + IG +GNG KSGSMR+GKD ++FTK T+T SQT+ E
Sbjct: 98 LHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLE 157
Query: 136 EESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGKCG 195
V+VP+ + + ++ + + ++E I YS F E +L+ QFD I GK G
Sbjct: 158 CVQAQAVIVPIVPFNQQNKKMIITEDSLPSLE--AILNYSIFNRENDLLAQFDAIPGKKG 215
Query: 196 TLLVIYNLKLLLNGEPELDVKTDKEDILMA----------GALEDFP-ARWSFRAYTSVL 244
T ++I+N++ NG+ ELD TD+ DIL++ G + P +S RA+ +L
Sbjct: 216 TRVLIWNIRRNKNGKSELDFDTDQYDILVSDFDTEEKMTGGVTSELPETEYSLRAFCGIL 275
Query: 245 YFNPWMRIFIQAKRVKTKHLC-------YCLYRP---RKYLYVTSSF 281
Y P M+IF++ K+V T+ + Y Y+P K + +T F
Sbjct: 276 YMKPRMKIFLRQKKVTTQMIAKSLANVEYDTYKPTFTNKQVRITFGF 322
Score = 74.7 bits (182), Expect = 4e-13
Identities = 64/234 (27%), Positives = 101/234 (43%), Gaps = 32/234 (13%)
Query: 348 TARTLSLFYGVNVENRSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEV 407
T + + + +G + +N +Q G+ +Y NNRLIK EKVG Q+K G GV+G++
Sbjct: 312 TNKQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRGEGVGVIGVIEC--NF 369
Query: 408 MEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPL 467
++P++NKQ+F +EY + + Q L Y K+ + T V +P+
Sbjct: 370 LKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQDNFETS-----------TVARPI 418
Query: 468 NSFQYQRRQAMGIPFIIQCDLCLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVE 527
Q +QCD CLKWR LP + W C N + C
Sbjct: 419 PKVPDQTW--------VQCDECLKWRKLPGKID--PSMLPARWFCYYNSHPKYRRC---- 464
Query: 528 CLPSIPLGTMSTISPSKNEKEKQLRESVIKY----QNRLAEQQPQPQFIPVDEI 577
+P T + SK +K++Q E K +N P P+ + V E+
Sbjct: 465 SVPEEQELTDEDLCLSKAKKQEQTVEEKKKMPMENENHQVFSNP-PKILTVQEM 517
>gi|145553971 zinc finger, CW type with coiled-coil domain 2 isoform
b [Homo sapiens]
Length = 900
Score = 162 bits (410), Expect = 1e-39
Identities = 102/287 (35%), Positives = 160/287 (55%), Gaps = 25/287 (8%)
Query: 17 FIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEE 76
++ +NS++H+ F A+AELLDNA D VF +D E+++ L F DDGCGM+P +
Sbjct: 39 YLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVF-IDVEEVKNKSCLTFTDDGCGMTPHK 97
Query: 77 ASDIIYFGRSKKRLSTLKF-IGQYGNGLKSGSMRIGKDFILFTKKEETMTCVFFSQTFCE 135
++ FG + K + + IG +GNG KSGSMR+GKD ++FTK T+T SQT+ E
Sbjct: 98 LHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLE 157
Query: 136 EESLSEVVVPMPSWLIRTRESVTDDPQKFAMELSIIYKYSPFKTEAELMQQFDVIYGKCG 195
V+VP+ + + ++ + + ++E I YS F E +L+ QFD I GK G
Sbjct: 158 CVQAQAVIVPIVPFNQQNKKMIITEDSLPSLE--AILNYSIFNRENDLLAQFDAIPGKKG 215
Query: 196 TLLVIYNLKLLLNGEPELDVKTDKEDILMA----------GALEDFP-ARWSFRAYTSVL 244
T ++I+N++ NG+ ELD TD+ DIL++ G + P +S RA+ +L
Sbjct: 216 TRVLIWNIRRNKNGKSELDFDTDQYDILVSDFDTEEKMTGGVTSELPETEYSLRAFCGIL 275
Query: 245 YFNPWMRIFIQAKRVKTKHLC-------YCLYRP---RKYLYVTSSF 281
Y P M+IF++ K+V T+ + Y Y+P K + +T F
Sbjct: 276 YMKPRMKIFLRQKKVTTQMIAKSLANVEYDTYKPTFTNKQVRITFGF 322
Score = 74.7 bits (182), Expect = 4e-13
Identities = 64/234 (27%), Positives = 101/234 (43%), Gaps = 32/234 (13%)
Query: 348 TARTLSLFYGVNVENRSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGAGVVGIVNIPLEV 407
T + + + +G + +N +Q G+ +Y NNRLIK EKVG Q+K G GV+G++
Sbjct: 312 TNKQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRGEGVGVIGVIEC--NF 369
Query: 408 MEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGYQNDIDVEKPL 467
++P++NKQ+F +EY + + Q L Y K+ + T V +P+
Sbjct: 370 LKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQDNFETS-----------TVARPI 418
Query: 468 NSFQYQRRQAMGIPFIIQCDLCLKWRVLPSSTNYQEKEFFDIWICANNPNRLENSCHQVE 527
Q +QCD CLKWR LP + W C N + C
Sbjct: 419 PKVPDQTW--------VQCDECLKWRKLPGKID--PSMLPARWFCYYNSHPKYRRC---- 464
Query: 528 CLPSIPLGTMSTISPSKNEKEKQLRESVIKY----QNRLAEQQPQPQFIPVDEI 577
+P T + SK +K++Q E K +N P P+ + V E+
Sbjct: 465 SVPEEQELTDEDLCLSKAKKQEQTVEEKKKMPMENENHQVFSNP-PKILTVQEM 517
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 45.1 bits (105), Expect = 3e-04
Identities = 99/501 (19%), Positives = 209/501 (41%), Gaps = 58/501 (11%)
Query: 286 KDEVKKAEEAVKIAESILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAKQKNLKEKQRE 345
K E+KK + ++ AE +K +I+ N + SS + R L+ E K NL+E E
Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKN-----AESSKASSITRELQGRELKLTNLQENLSE 795
Query: 346 LKTAR-TLSLFYGVNVENRSQAGMFIYSNNRLI-----KMHEKVGSQLKLKSLLGAGVVG 399
+ + TL + E ++A S R + K+H+K L S L
Sbjct: 796 VSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN 855
Query: 400 IVNIPLEVMEPSHNKQEFLNVQE--YNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGY 457
+ ++ + E +++ + +E N + ++M K +G N+ LT +E
Sbjct: 856 LADMEAKFREKDEREEQLIKAKEKLENDIAEIM--------KMSGDNSSQLTKMNDELRL 907
Query: 458 QNDIDVEKPLNSFQYQRRQAMGIPFIIQCDLCLK---WRVLPSSTNYQEKEFFDIWICAN 514
+ + DVE+ A + I+ D+ +K + + + +EK+ + + ++
Sbjct: 908 K-ERDVEELQLKLTKANENASFLQKSIE-DMTVKAEQSQQEAAKKHEEEKKELERKL-SD 964
Query: 515 NPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRL--AEQQPQPQFI 572
++E S +Q + L + S E + L+++++ +++L A ++
Sbjct: 965 LEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQ 1024
Query: 573 PVDEI-----------TVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQ 621
++E+ T KT+ + L D + + EL +
Sbjct: 1025 ELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENN 1084
Query: 622 KRNIEETDSDVEYIS-ETKIMK------KSMEEKMNSQQQRIPVALPENVKLAERSQRSQ 674
+N+EE + E ++ E + M+ +++++ + Q++ ENVKLAE RS+
Sbjct: 1085 LKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSR 1144
Query: 675 IANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDENTSDSDIILVSDK- 733
+T+ + + L N EMK+++S F+++ ++E S I ++
Sbjct: 1145 -DEVTSHQKLEEERSVLNNQLL---EMKKRES-KFIKD----ADEEKASLQKSISITSAL 1195
Query: 734 -SNTDVSLKQEKKEIPLLNQE 753
+ D L++ + E+ +L E
Sbjct: 1196 LTEKDAELEKLRNEVTVLRGE 1216
Score = 36.6 bits (83), Expect = 0.12
Identities = 95/470 (20%), Positives = 187/470 (39%), Gaps = 68/470 (14%)
Query: 515 NPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNR-LAEQQPQPQFIP 573
N E + H E + ++ M I +N E +R + K +++ L E + +
Sbjct: 633 NQQDSERAAHAKE-MEALRAKLMKVIKEKENSLEA-IRSKLDKAEDQHLVEMEDTLNKLQ 690
Query: 574 VDEITVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVE 633
EI V + A K N +T+ I LK +L A R+
Sbjct: 691 EAEIKVKELEVLQA-KCNEQTKVIDNFTSQLKATEEKLLDLDALRKAS------------ 737
Query: 634 YISETKIMKKSMEEKMNSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKN 693
SE K K + +++ + +++I +++++ + ++ S+ ++IT Q E L N
Sbjct: 738 --SEGKSEMKKLRQQLEAAEKQI-----KHLEIEKNAESSKASSITR--ELQGRELKLTN 788
Query: 694 AQAASWEMKR-KQSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVS-LKQEKKEIPLLN 751
Q E+ + K++L +E ++L E + + + V V+ L Q++++ +L+
Sbjct: 789 LQENLSEVSQVKETLE--KELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLS 846
Query: 752 QEKQELCNDVLAMK--------RSSSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVA 803
+ ++L ++ M+ R L K L + ++ SG
Sbjct: 847 SDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD------------- 893
Query: 804 SSPASSQSTPVKETVRKLKSKLREILLYFFPEHQ----LPSELEEPALSCELEQCP---- 855
SSQ T + + +R + + E+ L ++ L +E+ + E Q
Sbjct: 894 ---NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK 950
Query: 856 -EQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNEISLGQCENKRKISE 914
E+ K+L+ + ++ + + + K + S T+ H EI L + +E
Sbjct: 951 HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEI-LQNLQKTLLDTE 1009
Query: 915 DKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQNNLNK 964
DKLK R + + LLQ+L E +Q D A ED + + K
Sbjct: 1010 DKLKGAREENSGLLQEL-----EELRKQADKAKAAQTAEDAMQIMEQMTK 1054
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 45.1 bits (105), Expect = 3e-04
Identities = 99/501 (19%), Positives = 209/501 (41%), Gaps = 58/501 (11%)
Query: 286 KDEVKKAEEAVKIAESILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAKQKNLKEKQRE 345
K E+KK + ++ AE +K +I+ N + SS + R L+ E K NL+E E
Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKN-----AESSKASSITRELQGRELKLTNLQENLSE 830
Query: 346 LKTAR-TLSLFYGVNVENRSQAGMFIYSNNRLI-----KMHEKVGSQLKLKSLLGAGVVG 399
+ + TL + E ++A S R + K+H+K L S L
Sbjct: 831 VSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN 890
Query: 400 IVNIPLEVMEPSHNKQEFLNVQE--YNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEFGY 457
+ ++ + E +++ + +E N + ++M K +G N+ LT +E
Sbjct: 891 LADMEAKFREKDEREEQLIKAKEKLENDIAEIM--------KMSGDNSSQLTKMNDELRL 942
Query: 458 QNDIDVEKPLNSFQYQRRQAMGIPFIIQCDLCLK---WRVLPSSTNYQEKEFFDIWICAN 514
+ + DVE+ A + I+ D+ +K + + + +EK+ + + ++
Sbjct: 943 K-ERDVEELQLKLTKANENASFLQKSIE-DMTVKAEQSQQEAAKKHEEEKKELERKL-SD 999
Query: 515 NPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRL--AEQQPQPQFI 572
++E S +Q + L + S E + L+++++ +++L A ++
Sbjct: 1000 LEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQ 1059
Query: 573 PVDEI-----------TVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQ 621
++E+ T KT+ + L D + + EL +
Sbjct: 1060 ELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENN 1119
Query: 622 KRNIEETDSDVEYIS-ETKIMK------KSMEEKMNSQQQRIPVALPENVKLAERSQRSQ 674
+N+EE + E ++ E + M+ +++++ + Q++ ENVKLAE RS+
Sbjct: 1120 LKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSR 1179
Query: 675 IANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDENTSDSDIILVSDK- 733
+T+ + + L N EMK+++S F+++ ++E S I ++
Sbjct: 1180 -DEVTSHQKLEEERSVLNNQLL---EMKKRES-KFIKD----ADEEKASLQKSISITSAL 1230
Query: 734 -SNTDVSLKQEKKEIPLLNQE 753
+ D L++ + E+ +L E
Sbjct: 1231 LTEKDAELEKLRNEVTVLRGE 1251
Score = 36.6 bits (83), Expect = 0.12
Identities = 95/470 (20%), Positives = 187/470 (39%), Gaps = 68/470 (14%)
Query: 515 NPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNR-LAEQQPQPQFIP 573
N E + H E + ++ M I +N E +R + K +++ L E + +
Sbjct: 668 NQQDSERAAHAKE-MEALRAKLMKVIKEKENSLEA-IRSKLDKAEDQHLVEMEDTLNKLQ 725
Query: 574 VDEITVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVE 633
EI V + A K N +T+ I LK +L A R+
Sbjct: 726 EAEIKVKELEVLQA-KCNEQTKVIDNFTSQLKATEEKLLDLDALRKAS------------ 772
Query: 634 YISETKIMKKSMEEKMNSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKN 693
SE K K + +++ + +++I +++++ + ++ S+ ++IT Q E L N
Sbjct: 773 --SEGKSEMKKLRQQLEAAEKQI-----KHLEIEKNAESSKASSITR--ELQGRELKLTN 823
Query: 694 AQAASWEMKR-KQSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVS-LKQEKKEIPLLN 751
Q E+ + K++L +E ++L E + + + V V+ L Q++++ +L+
Sbjct: 824 LQENLSEVSQVKETLE--KELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLS 881
Query: 752 QEKQELCNDVLAMK--------RSSSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVA 803
+ ++L ++ M+ R L K L + ++ SG
Sbjct: 882 SDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD------------- 928
Query: 804 SSPASSQSTPVKETVRKLKSKLREILLYFFPEHQ----LPSELEEPALSCELEQCP---- 855
SSQ T + + +R + + E+ L ++ L +E+ + E Q
Sbjct: 929 ---NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK 985
Query: 856 -EQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNEISLGQCENKRKISE 914
E+ K+L+ + ++ + + + K + S T+ H EI L + +E
Sbjct: 986 HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEI-LQNLQKTLLDTE 1044
Query: 915 DKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQNNLNK 964
DKLK R + + LLQ+L E +Q D A ED + + K
Sbjct: 1045 DKLKGAREENSGLLQEL-----EELRKQADKAKAAQTAEDAMQIMEQMTK 1089
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 42.4 bits (98), Expect = 0.002
Identities = 74/344 (21%), Positives = 136/344 (39%), Gaps = 22/344 (6%)
Query: 545 NEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLLGDDL 604
+E KQ+ E Y+ AE + + ++++T K T R +D
Sbjct: 642 DELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA 701
Query: 605 KHESLSSF-----ELSASRR---GQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRI 656
E S + EL+ ++ QK N ++ I+ + K MEEK+++ ++ +
Sbjct: 702 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 761
Query: 657 PVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVL 716
E KL ++ + A + E + ++ + K + E+ KV
Sbjct: 762 ASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 821
Query: 717 TEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKR----SSSLPS 772
+E + +K N LK +++E+ L Q+ Q+ ++ MKR SS L
Sbjct: 822 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 881
Query: 773 WK-SLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLY 831
K +N ++V + +S +S S Q +++ V++L+++L E
Sbjct: 882 DKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK-- 939
Query: 832 FFPEHQ-LPSELEEPALSCELEQCPEQMNKKLK----MCFNQIQ 870
+HQ + S L Q E + K LK MC NQ Q
Sbjct: 940 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQ 981
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 42.4 bits (98), Expect = 0.002
Identities = 74/344 (21%), Positives = 136/344 (39%), Gaps = 22/344 (6%)
Query: 545 NEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLLGDDL 604
+E KQ+ E Y+ AE + + ++++T K T R +D
Sbjct: 631 DELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA 690
Query: 605 KHESLSSF-----ELSASRR---GQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRI 656
E S + EL+ ++ QK N ++ I+ + K MEEK+++ ++ +
Sbjct: 691 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 750
Query: 657 PVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVL 716
E KL ++ + A + E + ++ + K + E+ KV
Sbjct: 751 ASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 810
Query: 717 TEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKR----SSSLPS 772
+E + +K N LK +++E+ L Q+ Q+ ++ MKR SS L
Sbjct: 811 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 870
Query: 773 WK-SLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLY 831
K +N ++V + +S +S S Q +++ V++L+++L E
Sbjct: 871 DKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK-- 928
Query: 832 FFPEHQ-LPSELEEPALSCELEQCPEQMNKKLK----MCFNQIQ 870
+HQ + S L Q E + K LK MC NQ Q
Sbjct: 929 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQ 970
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 42.4 bits (98), Expect = 0.002
Identities = 74/344 (21%), Positives = 136/344 (39%), Gaps = 22/344 (6%)
Query: 545 NEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLLGDDL 604
+E KQ+ E Y+ AE + + ++++T K T R +D
Sbjct: 610 DELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA 669
Query: 605 KHESLSSF-----ELSASRR---GQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRI 656
E S + EL+ ++ QK N ++ I+ + K MEEK+++ ++ +
Sbjct: 670 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 729
Query: 657 PVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVL 716
E KL ++ + A + E + ++ + K + E+ KV
Sbjct: 730 ASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 789
Query: 717 TEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKR----SSSLPS 772
+E + +K N LK +++E+ L Q+ Q+ ++ MKR SS L
Sbjct: 790 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 849
Query: 773 WK-SLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLY 831
K +N ++V + +S +S S Q +++ V++L+++L E
Sbjct: 850 DKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK-- 907
Query: 832 FFPEHQ-LPSELEEPALSCELEQCPEQMNKKLK----MCFNQIQ 870
+HQ + S L Q E + K LK MC NQ Q
Sbjct: 908 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQ 949
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.4 bits (98), Expect = 0.002
Identities = 74/344 (21%), Positives = 136/344 (39%), Gaps = 22/344 (6%)
Query: 545 NEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLLGDDL 604
+E KQ+ E Y+ AE + + ++++T K T R +D
Sbjct: 639 DELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA 698
Query: 605 KHESLSSF-----ELSASRR---GQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRI 656
E S + EL+ ++ QK N ++ I+ + K MEEK+++ ++ +
Sbjct: 699 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 758
Query: 657 PVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVL 716
E KL ++ + A + E + ++ + K + E+ KV
Sbjct: 759 ASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818
Query: 717 TEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKR----SSSLPS 772
+E + +K N LK +++E+ L Q+ Q+ ++ MKR SS L
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 878
Query: 773 WK-SLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLY 831
K +N ++V + +S +S S Q +++ V++L+++L E
Sbjct: 879 DKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK-- 936
Query: 832 FFPEHQ-LPSELEEPALSCELEQCPEQMNKKLK----MCFNQIQ 870
+HQ + S L Q E + K LK MC NQ Q
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQ 978
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.4 bits (98), Expect = 0.002
Identities = 74/344 (21%), Positives = 136/344 (39%), Gaps = 22/344 (6%)
Query: 545 NEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLLGDDL 604
+E KQ+ E Y+ AE + + ++++T K T R +D
Sbjct: 639 DELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA 698
Query: 605 KHESLSSF-----ELSASRR---GQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRI 656
E S + EL+ ++ QK N ++ I+ + K MEEK+++ ++ +
Sbjct: 699 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 758
Query: 657 PVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVL 716
E KL ++ + A + E + ++ + K + E+ KV
Sbjct: 759 ASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818
Query: 717 TEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKR----SSSLPS 772
+E + +K N LK +++E+ L Q+ Q+ ++ MKR SS L
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 878
Query: 773 WK-SLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLY 831
K +N ++V + +S +S S Q +++ V++L+++L E
Sbjct: 879 DKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK-- 936
Query: 832 FFPEHQ-LPSELEEPALSCELEQCPEQMNKKLK----MCFNQIQ 870
+HQ + S L Q E + K LK MC NQ Q
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQ 978
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 42.4 bits (98), Expect = 0.002
Identities = 74/344 (21%), Positives = 136/344 (39%), Gaps = 22/344 (6%)
Query: 545 NEKEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLLGDDL 604
+E KQ+ E Y+ AE + + ++++T K T R +D
Sbjct: 639 DELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA 698
Query: 605 KHESLSSF-----ELSASRR---GQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQRI 656
E S + EL+ ++ QK N ++ I+ + K MEEK+++ ++ +
Sbjct: 699 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 758
Query: 657 PVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVL 716
E KL ++ + A + E + ++ + K + E+ KV
Sbjct: 759 ASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVH 818
Query: 717 TEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKR----SSSLPS 772
+E + +K N LK +++E+ L Q+ Q+ ++ MKR SS L
Sbjct: 819 SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEE 878
Query: 773 WK-SLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLY 831
K +N ++V + +S +S S Q +++ V++L+++L E
Sbjct: 879 DKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK-- 936
Query: 832 FFPEHQ-LPSELEEPALSCELEQCPEQMNKKLK----MCFNQIQ 870
+HQ + S L Q E + K LK MC NQ Q
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQ 978
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 41.6 bits (96), Expect = 0.004
Identities = 56/244 (22%), Positives = 106/244 (43%), Gaps = 32/244 (13%)
Query: 589 KENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEK 648
KE +KI++L + +K + L +R+ EE + +SE K M +M+ K
Sbjct: 717 KEQHYEEKIKVLDNQIKKDLADKETLENM---MQRHEEEAHEKGKILSEQKAMINAMDSK 773
Query: 649 MNSQQQRIPVALPENVKLAERS----QRSQIANITTVWRAQPTEGCLKNAQAASWEMKRK 704
+ S +QRI V L E KLA S QR+ A + + + L+ QA E + +
Sbjct: 774 IRSLEQRI-VELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLE-TQAGKLEAQNR 831
Query: 705 QSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAM 764
+ +EE ++ SD + +L + +VSL+ E++++ L K++L L++
Sbjct: 832 K----LEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLEL----KRQLTELQLSL 883
Query: 765 KRSSSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSK 824
+ S L++ AR ++ + A + + +E ++ L +
Sbjct: 884 QERES---------------QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAH 928
Query: 825 LREI 828
EI
Sbjct: 929 RDEI 932
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 41.6 bits (96), Expect = 0.004
Identities = 101/501 (20%), Positives = 204/501 (40%), Gaps = 106/501 (21%)
Query: 544 KNEKEKQLRESVIKYQNRLAEQQ---PQPQFIPVD-----EITVTSTCLTSAHK------ 589
K ++ KQL++ I+YQ +++ + +F+ + EIT + H+
Sbjct: 2017 KQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAE 2076
Query: 590 --------ENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVE---YISET 638
++T+++ R+L D+LK + EL +++ K +++ D D+E +E
Sbjct: 2077 LASFKVLLDDTQSEAARVLADNLKLKK----ELQSNKESVKSQMKQKDEDLERRLEQAEE 2132
Query: 639 KIM--KKSMEEKMNSQQQ----------RIPVALPENVKLAERSQRSQIANITTVWRAQP 686
K + KK+M+EK+++ ++ I V L + K ++ Q + + +T +
Sbjct: 2133 KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTK 2192
Query: 687 TEGCLKN------AQAASWEMKRKQSLNFVEE--------CKVLTE-------------- 718
+ L++ +A WE K ++ EE C VL +
Sbjct: 2193 SMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKI 2252
Query: 719 DENTSDSDIILVSDKSNTDVSLKQ--------EKKEIPLLNQEKQELCNDVL--AMKRSS 768
+ + + D + K+ T+V L+Q E KE+ +E + L + K S
Sbjct: 2253 NISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLES 2312
Query: 769 SLPSWKSL---LNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVK-ETVRKLKSK 824
L S K L+ +E G++ + + +S S + + R+L S+
Sbjct: 2313 ELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSR 2372
Query: 825 LREILLYFFPEHQLPSEL--EEPALSCELEQCPEQMNKKLKMCFNQI-----QNTYMVQY 877
L E + E ++ S L +E A+ + + +Q +K++K N + +N + +
Sbjct: 2373 LHEEI--NMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEE 2430
Query: 878 EKKIKRKLQSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRIKLALLLQKLQLGGPE 937
KK K ++ T N Q ++ K S L+N R ++
Sbjct: 2431 NKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVK-SMSSLQNDRDRIV------------ 2477
Query: 938 GDLEQ-TDTYLEALLKEDNLL 957
GD +Q + +L +L++D L+
Sbjct: 2478 GDYQQLEERHLSIILEKDQLI 2498
Score = 30.8 bits (68), Expect = 6.5
Identities = 81/395 (20%), Positives = 149/395 (37%), Gaps = 47/395 (11%)
Query: 549 KQLRESVIKYQNRLAEQQPQPQFI-------PVDEITVTSTCLTSAHKENTKTQKIRLLG 601
+Q + IK L Q+ + + VD+ L + KEN + QK +L
Sbjct: 2403 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQ-QKAQL-- 2459
Query: 602 DDLKHESLSSFELSASRR-GQKRNIEETDSDV-----EYISETKIMKKSMEEKMNSQQQR 655
D +S+SS + R G + +EE + + I E ++E++ +
Sbjct: 2460 -DSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSH 2518
Query: 656 IPVALPENVKL-AERSQ-RSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEEC 713
+ EN KL AE Q R + + T+ +Q K + ++ + +
Sbjct: 2519 MDDLNSENAKLDAELIQYREDLNQVITIKDSQQ-----KQLLEVQLQQNKELENKYAKLE 2573
Query: 714 KVLTEDENTSDSDIILVSDKSNTDVSLKQEK----KEIPLLNQEKQELCNDVLAMKRSSS 769
+ L E E ++ D + +L++EK KEI L +L V A++ +
Sbjct: 2574 EKLKESEEANE-------DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGT 2626
Query: 770 LPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRK---LKSKLR 826
L + + L V E+V H S S K + KE +K ++ KL+
Sbjct: 2627 LGLYHAQLKVKEEEV-----HRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLK 2681
Query: 827 EILLYFFPEHQLPSELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQ 886
+ L + + + E A E + + + K+ +N + + R +
Sbjct: 2682 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMS 2741
Query: 887 SIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLR 921
S+ N+R NE L + + K S +L L+
Sbjct: 2742 SL---QNSRDHANE-ELDELKRKYDASLKELAQLK 2772
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 40.8 bits (94), Expect = 0.006
Identities = 94/496 (18%), Positives = 197/496 (39%), Gaps = 117/496 (23%)
Query: 543 SKNEKEKQLR-----ESVIKYQNRLAEQQPQPQFIPVDEITVTSTCL--------TSAHK 589
+K+++E L+ E ++ R QQ Q + E+ + ++ TS H+
Sbjct: 417 AKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHR 476
Query: 590 ENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMK--KSMEE 647
E + Q++ H+ L+ E + + R TD+D + +I K K E+
Sbjct: 477 EREQAQQL--------HQLLALKEQEHRKELETREFF-TDADFQDALAKEIAKEEKKHEQ 527
Query: 648 KMNSQQQRIPVA------LPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASW-E 700
+ Q++I V L ++A + + ++ + TE K+ A W +
Sbjct: 528 MIKEYQEKIDVLSQQYMDLENEFRIALTVEARRFQDVKDGFENVATE-LAKSKHALIWAQ 586
Query: 701 MKRKQSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVSL------------KQEKKEIP 748
K +S + +++ + +++ T +++ + ++ ++ KQ+ +I
Sbjct: 587 RKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIE 646
Query: 749 LLNQEKQELCNDVLAMK-------------------RSSSLPSWKSLLNVPMEDVNLSSG 789
LL EK +L +++ A + + SSL + L +E ++ +
Sbjct: 647 LLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENE 706
Query: 790 HIARVSVSGS------CKVASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPSELE 843
+ + + S S CK+ ET+RKLK L+E + + L+
Sbjct: 707 CLRKTNESDSDALRIKCKIIDDQT--------ETIRKLKDCLQE-------KDEHIKRLQ 751
Query: 844 EPALSCELEQCP-EQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNEIS 902
E E+E+C EQ+++K ++ + + +K++R HNE
Sbjct: 752 EKIT--EIEKCTQEQLDEK---------SSQLDEVLEKLER--------------HNERK 786
Query: 903 LGQCENKRKISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQNNL 962
+ + + K E +L+ +R + L +K D + +LE +KE F+N
Sbjct: 787 -EKLKQQLKGKEVELEEIRKAYSTLNRKWH------DKGELLCHLETQVKEVKEKFENKE 839
Query: 963 NKVTIDARHRLPLEKN 978
K+ + + L+KN
Sbjct: 840 KKLKAERDKSIELQKN 855
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 40.8 bits (94), Expect = 0.006
Identities = 94/496 (18%), Positives = 197/496 (39%), Gaps = 117/496 (23%)
Query: 543 SKNEKEKQLR-----ESVIKYQNRLAEQQPQPQFIPVDEITVTSTCL--------TSAHK 589
+K+++E L+ E ++ R QQ Q + E+ + ++ TS H+
Sbjct: 510 AKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHR 569
Query: 590 ENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMK--KSMEE 647
E + Q++ H+ L+ E + + R TD+D + +I K K E+
Sbjct: 570 EREQAQQL--------HQLLALKEQEHRKELETREFF-TDADFQDALAKEIAKEEKKHEQ 620
Query: 648 KMNSQQQRIPVA------LPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASW-E 700
+ Q++I V L ++A + + ++ + TE K+ A W +
Sbjct: 621 MIKEYQEKIDVLSQQYMDLENEFRIALTVEARRFQDVKDGFENVATE-LAKSKHALIWAQ 679
Query: 701 MKRKQSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVSL------------KQEKKEIP 748
K +S + +++ + +++ T +++ + ++ ++ KQ+ +I
Sbjct: 680 RKENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIE 739
Query: 749 LLNQEKQELCNDVLAMK-------------------RSSSLPSWKSLLNVPMEDVNLSSG 789
LL EK +L +++ A + + SSL + L +E ++ +
Sbjct: 740 LLKHEKVQLISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKLEAQIESLSRENE 799
Query: 790 HIARVSVSGS------CKVASSPASSQSTPVKETVRKLKSKLREILLYFFPEHQLPSELE 843
+ + + S S CK+ ET+RKLK L+E + + L+
Sbjct: 800 CLRKTNESDSDALRIKCKIIDDQT--------ETIRKLKDCLQE-------KDEHIKRLQ 844
Query: 844 EPALSCELEQCP-EQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNEIS 902
E E+E+C EQ+++K ++ + + +K++R HNE
Sbjct: 845 EKIT--EIEKCTQEQLDEK---------SSQLDEVLEKLER--------------HNERK 879
Query: 903 LGQCENKRKISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEALLKEDNLLFQNNL 962
+ + + K E +L+ +R + L +K D + +LE +KE F+N
Sbjct: 880 -EKLKQQLKGKEVELEEIRKAYSTLNRKWH------DKGELLCHLETQVKEVKEKFENKE 932
Query: 963 NKVTIDARHRLPLEKN 978
K+ + + L+KN
Sbjct: 933 KKLKAERDKSIELQKN 948
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 40.4 bits (93), Expect = 0.008
Identities = 86/421 (20%), Positives = 179/421 (42%), Gaps = 70/421 (16%)
Query: 514 NNPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQPQPQFIP 573
N +++ H++ L + ++ IS E+ E + + +N L QQ I
Sbjct: 224 NRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLL--QQGGSGVIE 281
Query: 574 VD-----EITVTSTCLTSAHKENTKTQKIRLLGDDLK--HESLSSFELSASRRGQKRNIE 626
D E+ T L E+TK K+ L D +K ++ LSS E R+I
Sbjct: 282 TDLSKIYEMQKTIQVLQIEKVESTK--KMEQLEDKIKDINKKLSSAE-------NDRDIL 332
Query: 627 ETDSDVEYISETKIMKKSMEEKMNSQQQRIPVALPENVKLAERSQ-RSQIANITTVWRAQ 685
+ + + + +IM++ K+ + + P A+ ++ + E+ + +Q A++ V+R Q
Sbjct: 333 RREQEQLNVEKRQIMEECENLKLECSKLQ-PSAVKQSDTMTEKERILAQSASVEEVFRLQ 391
Query: 686 PTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVSLKQEKK 745
+N E+ R SLN D L D + ++ +K
Sbjct: 392 QALSDAEN------EIMRLSSLN----------------QDNSLAEDNLKLKMRIEVLEK 429
Query: 746 EIPLLNQEKQELCNDVLAMKRSSSLPSWKSLLNVPMEDVNLSSG-HIARVSVSGSCKVAS 804
E LL+QEK+EL +L + ++ + + D++L S H R+++ + +
Sbjct: 430 EKSLLSQEKEELQMSLLKLNN-----EYEVIKSTATRDISLDSELHDLRLNLEAKEQELN 484
Query: 805 SPASSQST---PVKETVRKLKSKLREILLYFFPEHQLPSELEE-PALSCELEQCPEQMNK 860
S + T ++E R+ + + ++L + QL + E ++ +L+Q K
Sbjct: 485 QSISEKETLIAEIEELDRQNQEATKHMILI---KDQLSKQQNEGDSIISKLKQDLNDEKK 541
Query: 861 KLKMCFNQIQNTYM-VQYEKKIKRKLQSIIYDSNTRGIHNEISLGQCENKRKISEDKLKN 919
++ +Q+++ M + E ++++ + I +E++L ++ EDK++N
Sbjct: 542 RV----HQLEDDKMDITKELDVQKE----------KLIQSEVALNDLHLTKQKLEDKVEN 587
Query: 920 L 920
L
Sbjct: 588 L 588
>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
Length = 1079
Score = 39.7 bits (91), Expect = 0.014
Identities = 99/491 (20%), Positives = 192/491 (39%), Gaps = 59/491 (12%)
Query: 536 TMSTISPSKNEKEKQLRESVIKYQ-NRLAEQQPQPQFIPVDEITVTSTCLTSAHKENTKT 594
T+ + SK +K++ E K Q + LA++ Q +++ T T KEN +
Sbjct: 125 TLKALQVSKYSLQKKVSEMEQKVQLHLLAKEDYHKQLSEIEKYYATITGQFGLVKENHEK 184
Query: 595 --QKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDV-------EY-ISETKIMKKS 644
Q +R K S + + A K+ +++ SD+ +Y + E I
Sbjct: 185 LEQNVREAIQSNKRLSALNKKQEAEICSLKKELKKAASDLIKSKVTCQYKMGEENINLTI 244
Query: 645 MEEKMNSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRK 704
E+K Q+R+ + L N K+ E Q + Q + L+ A+ EM+
Sbjct: 245 KEQKFQELQERLNMELELNEKINEEITHIQEEKQDIIISFQHMQQLLRQQIQANTEME-- 302
Query: 705 QSLNFVEECKVLTEDENTSDSDIIL----VSDKSNTDVSLKQE--------KKEIPLLNQ 752
E KVL E+ T + D L V + ++L+ E K+ LN
Sbjct: 303 ------AELKVLKENNQTLERDNELQREKVKENEEKFLNLQNEHEKALGTWKRHAEELNG 356
Query: 753 EKQELCNDVLAMKRS--SSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQ 810
E ++ N++ ++K + + L N + + ++ V+ S S S+
Sbjct: 357 EINKIKNELSSLKETHIKLQEHYNKLCNQKTFEEDKKFQNVPEVNNENS---EMSTEKSE 413
Query: 811 STPVKE--TVRKLKSKLREILL----YFFPEHQLPSELEEPALSCELEQCPEQMNKKLKM 864
+T +++ T ++++ + E Y E + E + +L+ + ++
Sbjct: 414 NTIIQKYNTEQEIREENMENFCSDTEYREKEEKKEGSFIEEIIIDDLQLFEKSFKNEIDT 473
Query: 865 CFNQIQN------TYMVQYEKKIKRKLQSIIYDSNTRGIHNEISLGQC-ENKRKISEDKL 917
+Q +N + + +K++ + Q+ N + + EI C E +E K
Sbjct: 474 VVSQDENQSEISLSKTLSLDKEVISQGQTSNVTDNRKSVTTEIKDKICLEKDNGCTEFKS 533
Query: 918 KN---LRIKLALLLQKLQLGGPEG-DLEQTDTYLEALLKEDNLLFQNNLNKVTIDARHRL 973
N + + A+ +K+ L G D+ TD LE E+N + + N + + H
Sbjct: 534 PNNHFVVLDTAIETEKIHLERTRGLDVHHTDVNLEV---ENN---KTSFNSILNETAHNT 587
Query: 974 PLEKNEKTSEN 984
N+ SEN
Sbjct: 588 YHNNNKDVSEN 598
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
1 [Homo sapiens]
Length = 1412
Score = 39.3 bits (90), Expect = 0.018
Identities = 87/449 (19%), Positives = 171/449 (38%), Gaps = 58/449 (12%)
Query: 547 KEKQLRESVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKE-NTKTQKIRLLGDDLK 605
++K++ ES I Y+ R A++ + + V ++ LT +E K QK +L + L
Sbjct: 793 QQKEISESNIAYEKRKAKEAMEKEKKKVQDL---ENRLTKQKEELELKEQKEDVLNNKLS 849
Query: 606 H--------------ESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEKMNS 651
ESL + L+ +E T + + + E I+++ M + +
Sbjct: 850 DALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQD 909
Query: 652 QQQRIPVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVE 711
+Q+ E + + + I ++ K + K + + ++
Sbjct: 910 EQESQRHGFEEEIMEYKEQIKQHAQTIVSLEE--------KLQKVTQHHKKIEGEIATLK 961
Query: 712 ECKVLTEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKRSSSLP 771
+ ++E D + +++ S D++ + + LL +K+ L + MK L
Sbjct: 962 DNDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDD--LLAAQKEILSQQEVIMKLRKDLT 1019
Query: 772 SWKSLLNVPMEDVN------LSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKL 825
S ++ ++N L + S V + S+ V++ R+LK+ L
Sbjct: 1020 EAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVLKEKMAQMSSLVEKKDRELKA-L 1078
Query: 826 REILLYFFPEHQLPSELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKL 885
E L +H+L L+ E EQ P KK + C +Q V E +
Sbjct: 1079 EEALRASQEKHRLQ-------LNTEKEQKPR---KKTQTCDTSVQ-IEPVHTEAFSSSQE 1127
Query: 886 QSIIYDSNTRGIHNEISLGQCENKRKISEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDT 945
Q D R C+ R E+ ++ + L+ L +++ + D
Sbjct: 1128 QQSFSDLGVR----------CKGSRH--EEVIQRQKKALSELRARIKELEKARSPDHKDH 1175
Query: 946 YLEALLKEDNLLFQNNLNKVTIDARHRLP 974
E+ L NL +NN+ K+ +DA+ LP
Sbjct: 1176 QNESFLDLKNLRMENNVQKILLDAKPDLP 1204
Score = 36.6 bits (83), Expect = 0.12
Identities = 72/317 (22%), Positives = 128/317 (40%), Gaps = 68/317 (21%)
Query: 703 RKQSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVL 762
R+ ++C+VL ED + +I + K +I L + ++ L
Sbjct: 275 RQNEKEISQKCQVLDEDIDAKQKEI-------------QSLKSQISALQKGYSKVLCQTL 321
Query: 763 AMKRSSSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLK 822
+ +R+S + S K+ D ++SG ++ + K Q +KE V LK
Sbjct: 322 S-ERNSEITSLKNEGENLKRDNAITSGMVSSLQKDILAK------DEQVQQLKEEVSHLK 374
Query: 823 SKLREILLYFFPEHQLPS----------ELEEPALSCELEQCPEQMNKKLKMCFNQIQNT 872
S+ ++ +HQL + EL++ EL + E K+LK+C QIQ+
Sbjct: 375 SQNKD------KDHQLEALGSRCSVLKEELKQEDAHRELREAQE---KELKLCKTQIQD- 424
Query: 873 YMVQYEKKIKRKL------QSIIYDSNTRGIHNEISLGQCENKRKISEDKLKN----LRI 922
M + KK++ +L QS+I + E L + ++ + ++ N ++I
Sbjct: 425 -MEKEMKKLRAELRKSCTEQSVISRTLREKSKVEEKLQEDSRRKLLQLQEMGNRESVIKI 483
Query: 923 KLALLLQKLQ------------LGGPEGDLEQTDTYL---EALLKEDNLLFQNNLNKVTI 967
L + +L+ P D TD L + EDN+ FQ K T+
Sbjct: 484 NLERAVGQLEHFRSQVIKATYGRAKPFRDKPVTDQQLIEKITQVTEDNINFQQ--KKWTL 541
Query: 968 DARHRLPLEKNEKTSEN 984
+L K E+T+EN
Sbjct: 542 QKETQLSNSKQEETTEN 558
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 39.3 bits (90), Expect = 0.018
Identities = 141/717 (19%), Positives = 274/717 (38%), Gaps = 115/717 (16%)
Query: 286 KDEVK--KAEEAVKIAESILKEAQIKVNQCDRTSLSSAK-----DVLQRALEDVEAKQKN 338
KD V K ++A E +L ++K N C+ ++ K +VLQR L + + +
Sbjct: 720 KDSVSLLKIQDAALSCERLL---ELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQ 776
Query: 339 LKEKQRELKTARTLSLFYGVNVEN---RSQAGMFIYSNNRLIKMHEKVGSQLKLKSLLGA 395
L+ ++ E + SL + +N E R+ ++ +L + E+ ++++K L
Sbjct: 777 LEHQKVEWER-ELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLE- 834
Query: 396 GVVGIVNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGINNRNLTLFCNEF 455
+ + + +E+ N + VQE N + + + GI N
Sbjct: 835 --LSLQTLEMELRTVKSNLNQV--VQERNDAQRQLSREQNARMLQDGI-------LTNHL 883
Query: 456 GYQNDIDV-EKPLNS----FQYQRRQAMGIPFIIQCDLC-LKWRVLPSSTNYQEKE---F 506
Q +I++ +K +NS + + ++Q ++ L+ + QEKE F
Sbjct: 884 SKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCF 943
Query: 507 FDIWICANNPNRLENSCHQVECLPSIPL----GTMSTISP------SKNEKEKQLRE--- 553
D+ I L+ + Q E + + G +S ++ SK E EKQ +E
Sbjct: 944 EDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLE 1003
Query: 554 -SVIKYQNRLA-------EQQPQPQFIPVDEITVTSTCLTSAHKENTKTQKIR----LLG 601
V Y +RLA + + + + + C K N ++ +L
Sbjct: 1004 AEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILS 1063
Query: 602 DDL-KHES-LSSFELSASR-----RGQKRNIEETDSDVEYISETKIMKKSMEEKMNSQQQ 654
L K ES L+S E+ R + +E D +S+T+ K ME+K ++Q
Sbjct: 1064 QQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKD---LSQTQCQMKEMEQKYQNEQV 1120
Query: 655 RIPVALPENVKLAERSQRSQIANI------------------TTVWRAQPTEGCLKNAQA 696
++ + + + ER + Q N+ T + ++ QA
Sbjct: 1121 KVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQA 1180
Query: 697 ASWEMKRKQSLNFVEECK-VLTEDENTSDSDIILVSDKSNTDVSLKQEKKEI--PLLNQE 753
S KQSL E K +++E + + ++K+ +V ++Q ++E+ L Q
Sbjct: 1181 ES----EKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQS 1236
Query: 754 KQELCNDVLAMKR----SSSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASS 809
E +V + R + K L + + H V + +
Sbjct: 1237 MSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEK 1296
Query: 810 QSTPVKETVRKLKSKLREILLYFFPEHQLPSELEE--------PALSCELEQCPEQMNKK 861
+ +K TV+K K+ E+ + E E+ +L C L+Q +M K
Sbjct: 1297 DNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQ---EMKKN 1353
Query: 862 LKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIHNEISLGQCENKRKISEDKLK 918
+++ + + T K ++KL Y++ H ++ Q E +I++ K K
Sbjct: 1354 VEL---EREITGFKNLLKMTRKKLNE--YENGEFSFHGDLKTSQFEMDIQINKLKHK 1405
Score = 33.5 bits (75), Expect = 1.0
Identities = 92/451 (20%), Positives = 173/451 (38%), Gaps = 73/451 (16%)
Query: 517 NRLENSCHQV-ECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNR-------LAEQQPQ 568
N LE H + L LG + + ++ + Q++E KYQN + +Q+
Sbjct: 1074 NSLEIEFHHTRDALREKTLG-LERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESV 1132
Query: 569 PQFIPV--DEITVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIE 626
+ + E + L AH + +K + D H + +L A Q +E
Sbjct: 1133 EERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQ--KLQAESEKQSLLLE 1190
Query: 627 ETDSDVEYISETKIMKKSMEEKMNSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQP 686
E + E ISE +K+ + N + +R V +LA+ ++ ++ + +
Sbjct: 1191 ERNK--ELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL----EV 1244
Query: 687 TEGCLKNAQAASWEMKRK--QSLNFVEECKVLTED-----ENTSDSDIILVSDKSNTDVS 739
T N + + ++K+K Q N ++E + + E D L D + V+
Sbjct: 1245 TSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVT 1304
Query: 740 LKQ--------------------EKKEIPLLNQEKQEL-CNDVLAMKRSSSLP----SWK 774
+K+ EK+++ L + KQ L CN MK++ L +K
Sbjct: 1305 VKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFK 1364
Query: 775 SLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKLKSKLREILLYFFP 834
+LL + + +N S G K + Q + KLK K+ +
Sbjct: 1365 NLLKMTRKKLNEYEN--GEFSFHGDLKTSQFEMDIQ-------INKLKHKIDD------- 1408
Query: 835 EHQLPSELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNT 894
L +ELE C Q+ ++ + +Q + +K K+KL+ + + +
Sbjct: 1409 ---LTAELETAGSKCLHLDTKNQILQEELLSMKTVQKK--CEKLQKNKKKLEQEVINLRS 1463
Query: 895 RGIHNEISLGQCEN-KRKISEDKLKNLRIKL 924
N + LGQ + K++I E + + KL
Sbjct: 1464 HIERNMVELGQVKQYKQEIEERARQEIAEKL 1494
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 38.9 bits (89), Expect = 0.024
Identities = 53/255 (20%), Positives = 98/255 (38%), Gaps = 37/255 (14%)
Query: 537 MSTISPSKNEKEKQLRESVIKYQNRLAEQQPQPQFIPVD------EITVTSTCLTSAHKE 590
+ + K E EKQ RE++ K + + Q+ + VD + L SA+KE
Sbjct: 607 LKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKE 666
Query: 591 NTKTQKIRLLGDDLKHESLSSFELSAS-------RRGQKRNIEETDSDVEYISETKIMKK 643
T K D E+ S E+ A + Q+ ++ ++ + + ++ +
Sbjct: 667 LTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQ 726
Query: 644 SMEE-----------KMNSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQPTEGCLK 692
E+ ++ QQR+ A N +L++ + + + Q T G
Sbjct: 727 RTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLG--- 783
Query: 693 NAQAASWEMKRKQSLNFVEECKVL----TEDENTSDSDI----ILVSDKSNTDVSLKQEK 744
+Q +SWE K + + E + L E E + ++ I +S + + L+QE
Sbjct: 784 -SQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQEN 842
Query: 745 KEIPL-LNQEKQELC 758
L EK LC
Sbjct: 843 SRFQAQLESEKNRLC 857
>gi|197245440 hypothetical protein LOC23285 [Homo sapiens]
Length = 1354
Score = 38.9 bits (89), Expect = 0.024
Identities = 60/287 (20%), Positives = 124/287 (43%), Gaps = 26/287 (9%)
Query: 514 NNPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQPQPQFIP 573
N+ + ++NS ++ P + ++ S +E++ + SV+K + +P PQ I
Sbjct: 336 NSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAIL 395
Query: 574 VDEITVTSTCLTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVE 633
+ TS T+A + T + ES +S + S S R N+ + D +
Sbjct: 396 --KKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNT- 452
Query: 634 YISETKIMKKSMEEKMNSQQQRIP---VALPENVKLAERSQRSQIANITTVWRAQPTEGC 690
+E + K+ M +++++ ++ VA+P+N+ +S++ + N + P
Sbjct: 453 -TTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNL---NQSKKGETLNNKDSKQKMPPGQV 508
Query: 691 LKNAQAASWEMKRKQSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLL 750
+ Q +S + K + V+ K + D V D +N D S+ ++K PL+
Sbjct: 509 ISKTQPSS-QRPLKHETSTVQ--KSMFHD----------VRDNNNKD-SVSEQKPHKPLI 554
Query: 751 NQEKQELCNDVLAMKRSSSLPSWKSLLNVPMEDVNLSSGHIARVSVS 797
N + +D A++ S K L + E + L +I+++ S
Sbjct: 555 NLASE--ISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKS 599
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 38.5 bits (88), Expect = 0.031
Identities = 147/709 (20%), Positives = 274/709 (38%), Gaps = 119/709 (16%)
Query: 287 DEVKKAEEAVKIAESILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAKQKNLKEKQREL 346
+E+ + E ++ A + E + K+N+ + SLS+ +D L+ + +K L+ K
Sbjct: 535 EELSFSREQIQRARQTIAEQESKLNEAHK-SLSTVED-LKAEIVSASESRKELELKHEAE 592
Query: 347 KTARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLK----------- 388
T + L +N SQ +L+ HE+ S+LK
Sbjct: 593 VTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINI 652
Query: 389 --LKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGINNR 446
LK LG ++ M +F E ++L+ Q +++ K +
Sbjct: 653 EKLKDNLGIHYKQQIDGLQNEMSQKIETMQF----EKDNLITKQNQLILEISKLKDLQQS 708
Query: 447 NLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGIPFIIQCDLCLKWRVLPSSTNYQEKEF 506
+ E Q + +++K + + + ++ + +Q +L LK +L +EKE
Sbjct: 709 LVNSKSEEMTLQIN-ELQKEIEILRQEEKEKGTLEQEVQ-ELQLKTELLEKQM--KEKE- 763
Query: 507 FDIWICANNPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQ 566
N L+ Q+E SI + EK+ E ++K +++++
Sbjct: 764 ----------NDLQEKFAQLEAENSIL------------KDEKKTLEDMLKIHTPVSQEE 801
Query: 567 PQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLL---GDDLKHESLSSFELSASRRGQ-- 621
+ I +D I S K++ ++I +L +DLK + + E +R
Sbjct: 802 ---RLIFLDSIK-------SKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFS 851
Query: 622 --KRNIEETDSDV--EYISETKIMKKSMEEKMNSQQQRIPVALPENVKLAERSQRSQIAN 677
++N E ++ EY K+ K +E+ N Q+ + +K Q N
Sbjct: 852 FAEKNFEVNYQELQEEYACLLKV-KDDLEDSKNKQE----LEYKSKLKALNEELHLQRIN 906
Query: 678 ITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDENTSDSDIILVSDKSNTD 737
TTV K A + EM + E + L E T + L S+
Sbjct: 907 PTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKL---EVTKREKLELSQRLSDLS 963
Query: 738 VSLKQEKKEIPLLNQEKQEL----------CND---VLAMKRSSSLPSWKSLLNVPMEDV 784
LKQ+ EI LN+E + L C + ++ R+ ++ S + ++ ++ V
Sbjct: 964 EQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGV 1023
Query: 785 NLSSGHIARVSVSGSCKVASSPASSQSTPVKETVR------KLKSKLREILLYFFPEHQL 838
+ A SVS KV S V++ V +SK +++L L
Sbjct: 1024 VTMTSRGAEGSVS---KVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLIL-----DHL 1075
Query: 839 PSELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGI- 897
PS +E +L +++ K+L + ++ QN +Q E +R S++Y ++ +
Sbjct: 1076 PSVTKESSLRATQPSENDKLQKELNVLKSE-QNDLRLQME--AQRICLSLVYSTHVDQVR 1132
Query: 898 ---HNEISLGQCENKRKI---SEDKLKNLR--IKLALLLQKLQLGGPEG 938
NE C K ++ E+K+K L+ +L L K Q G EG
Sbjct: 1133 EYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLELQTMKTQETGDEG 1181
Score = 31.6 bits (70), Expect = 3.8
Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 282 KGAFKDEVKKAEEAVKIA--------------ESILKEAQIKVNQCDRTSLSSAKDVLQR 327
+ F+ E++K E+ +K+ E + + K ++C LS K+ LQR
Sbjct: 2080 RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLS--KEQLQR 2137
Query: 328 ALEDVEAKQKNLKEKQRELKTARTLSLFYGVNVENRSQAG 367
+++ + + L+ + REL+ A +S VE+R G
Sbjct: 2138 DIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFG 2177
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 38.5 bits (88), Expect = 0.031
Identities = 147/709 (20%), Positives = 274/709 (38%), Gaps = 119/709 (16%)
Query: 287 DEVKKAEEAVKIAESILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAKQKNLKEKQREL 346
+E+ + E ++ A + E + K+N+ + SLS+ +D L+ + +K L+ K
Sbjct: 535 EELSFSREQIQRARQTIAEQESKLNEAHK-SLSTVED-LKAEIVSASESRKELELKHEAE 592
Query: 347 KTARTLSLFYGVNVEN-------RSQAGMFIYSNNRLIKMHEKVGSQLK----------- 388
T + L +N SQ +L+ HE+ S+LK
Sbjct: 593 VTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINI 652
Query: 389 --LKSLLGAGVVGIVNIPLEVMEPSHNKQEFLNVQEYNHLLKVMGQYLVQYCKDTGINNR 446
LK LG ++ M +F E ++L+ Q +++ K +
Sbjct: 653 EKLKDNLGIHYKQQIDGLQNEMSQKIETMQF----EKDNLITKQNQLILEISKLKDLQQS 708
Query: 447 NLTLFCNEFGYQNDIDVEKPLNSFQYQRRQAMGIPFIIQCDLCLKWRVLPSSTNYQEKEF 506
+ E Q + +++K + + + ++ + +Q +L LK +L +EKE
Sbjct: 709 LVNSKSEEMTLQIN-ELQKEIEILRQEEKEKGTLEQEVQ-ELQLKTELLEKQM--KEKE- 763
Query: 507 FDIWICANNPNRLENSCHQVECLPSIPLGTMSTISPSKNEKEKQLRESVIKYQNRLAEQQ 566
N L+ Q+E SI + EK+ E ++K +++++
Sbjct: 764 ----------NDLQEKFAQLEAENSIL------------KDEKKTLEDMLKIHTPVSQEE 801
Query: 567 PQPQFIPVDEITVTSTCLTSAHKENTKTQKIRLL---GDDLKHESLSSFELSASRRGQ-- 621
+ I +D I S K++ ++I +L +DLK + + E +R
Sbjct: 802 ---RLIFLDSIK-------SKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFS 851
Query: 622 --KRNIEETDSDV--EYISETKIMKKSMEEKMNSQQQRIPVALPENVKLAERSQRSQIAN 677
++N E ++ EY K+ K +E+ N Q+ + +K Q N
Sbjct: 852 FAEKNFEVNYQELQEEYACLLKV-KDDLEDSKNKQE----LEYKSKLKALNEELHLQRIN 906
Query: 678 ITTVWRAQPTEGCLKNAQAASWEMKRKQSLNFVEECKVLTEDENTSDSDIILVSDKSNTD 737
TTV K A + EM + E + L E T + L S+
Sbjct: 907 PTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKL---EVTKREKLELSQRLSDLS 963
Query: 738 VSLKQEKKEIPLLNQEKQEL----------CND---VLAMKRSSSLPSWKSLLNVPMEDV 784
LKQ+ EI LN+E + L C + ++ R+ ++ S + ++ ++ V
Sbjct: 964 EQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGV 1023
Query: 785 NLSSGHIARVSVSGSCKVASSPASSQSTPVKETVR------KLKSKLREILLYFFPEHQL 838
+ A SVS KV S V++ V +SK +++L L
Sbjct: 1024 VTMTSRGAEGSVS---KVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLIL-----DHL 1075
Query: 839 PSELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGI- 897
PS +E +L +++ K+L + ++ QN +Q E +R S++Y ++ +
Sbjct: 1076 PSVTKESSLRATQPSENDKLQKELNVLKSE-QNDLRLQME--AQRICLSLVYSTHVDQVR 1132
Query: 898 ---HNEISLGQCENKRKI---SEDKLKNLR--IKLALLLQKLQLGGPEG 938
NE C K ++ E+K+K L+ +L L K Q G EG
Sbjct: 1133 EYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLELQTMKTQETGDEG 1181
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 38.5 bits (88), Expect = 0.031
Identities = 34/148 (22%), Positives = 69/148 (46%), Gaps = 11/148 (7%)
Query: 839 PSELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIH 898
P+EL S +L C + ++ L+ + + V YE+ R LQS++ + R
Sbjct: 44 PAELFTNTRS-DLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRR 102
Query: 899 NEISLGQCENKRKI--------SEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEAL 950
L +N++ +E+K++ L K+ +LLQ+++ G EG +E+ ++ +
Sbjct: 103 GHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLV 162
Query: 951 --LKEDNLLFQNNLNKVTIDARHRLPLE 976
LKE+ L ++ + + A +E
Sbjct: 163 EQLKEERELLRSTTSTIESFAAQEKQME 190
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 38.5 bits (88), Expect = 0.031
Identities = 34/148 (22%), Positives = 69/148 (46%), Gaps = 11/148 (7%)
Query: 839 PSELEEPALSCELEQCPEQMNKKLKMCFNQIQNTYMVQYEKKIKRKLQSIIYDSNTRGIH 898
P+EL S +L C + ++ L+ + + V YE+ R LQS++ + R
Sbjct: 44 PAELFTNTRS-DLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRR 102
Query: 899 NEISLGQCENKRKI--------SEDKLKNLRIKLALLLQKLQLGGPEGDLEQTDTYLEAL 950
L +N++ +E+K++ L K+ +LLQ+++ G EG +E+ ++ +
Sbjct: 103 GHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLV 162
Query: 951 --LKEDNLLFQNNLNKVTIDARHRLPLE 976
LKE+ L ++ + + A +E
Sbjct: 163 EQLKEERELLRSTTSTIESFAAQEKQME 190
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 37.7 bits (86), Expect = 0.053
Identities = 73/346 (21%), Positives = 144/346 (41%), Gaps = 38/346 (10%)
Query: 593 KTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEKMNSQ 652
K KIRLL + L+HE + E Q + ++ ++ + + K +E+
Sbjct: 678 KDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCI 737
Query: 653 QQRIPVALPENVKLAERSQRS---QIANITTVWRAQPTEGCLKNAQAASWEMKRKQSLNF 709
Q++ E +K E + Q+A A TE + + K+ ++F
Sbjct: 738 QEK-----DEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSF 792
Query: 710 ---VEECKVLTED--------ENTSDSDIILVSDKSNT-DVSLKQEKKEIPLLNQEKQEL 757
VEE K + + E +++++ V++K T +S+ + +E+ L + K+E
Sbjct: 793 ASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQ 852
Query: 758 CND---VLAMKRSSSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPV 814
N VL K + K L ++ E+ +L + H+ V+ + K ASS +SQ +
Sbjct: 853 MNTMKAVLEEKEKDLANTGKWLQDLQEENESLKA-HVQEVA-QHNLKEASS--ASQFEEL 908
Query: 815 KETVRKLKSKLREILLYFFPEHQLPSELEEPALSCELEQCPEQMNKKLKMCFNQI-QNTY 873
+ +++ +++L+ + E L + + +L Q + NK K Q+ Q Y
Sbjct: 909 EIVLKEKENELKRL------EAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNY 962
Query: 874 MVQYEKKIKRKLQSII--YDSNTRGIHNEIS--LGQCENKRKISED 915
+L +I + G+ NE+ E++RK + D
Sbjct: 963 QQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNND 1008
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 37.7 bits (86), Expect = 0.053
Identities = 50/203 (24%), Positives = 85/203 (41%), Gaps = 24/203 (11%)
Query: 590 ENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKKSMEEKM 649
+ + Q RLL ++ + EL + GQ R E+ + ++ E K EE+
Sbjct: 368 QEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELK------EEEA 421
Query: 650 NSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQPTEGCLKNAQA---ASWEMKRKQS 706
Q+QRI +L E QR Q A V +A+ E ++ AQ E K KQ
Sbjct: 422 ARQRQRIK-------ELEEMQQRLQEALQLEV-KARRDEESVRIAQTRLLEEEEEKLKQL 473
Query: 707 LNFVEECKVLTEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDVLAMKR 766
+ EE + E + L + + SL+Q ++++ + Q +Q DV A +R
Sbjct: 474 MQLKEEQERYIERAQQEKEE--LQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQR 531
Query: 767 -----SSSLPSWKSLLNVPMEDV 784
S+++ W +N M +
Sbjct: 532 KLRQASTNVKHWNVQMNRLMHPI 554
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 37.7 bits (86), Expect = 0.053
Identities = 59/272 (21%), Positives = 116/272 (42%), Gaps = 37/272 (13%)
Query: 537 MSTISPSKNEKEKQLRE-----SVIKYQNRLAEQQPQPQFIPVDEITVTSTCLTSAHKEN 591
+S + KNE + +L E + + +++ A Q ++++ L A+KE
Sbjct: 1734 LSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQ---LEEANKEK 1790
Query: 592 TKTQ-KIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKI---------M 641
+ Q K++ L ++ S + S R Q+ I E ++ +E+ T++ +
Sbjct: 1791 QELQEKLQALQSQVEFLEQSMVDKSLVSR-QEAKIRELETRLEF-ERTQVKRLESLASRL 1848
Query: 642 KKSMEEKMNSQQQRIPVALPENV--KLAERSQRSQIANITTVWRAQPT--------EGCL 691
K++ME+ + QRI E K +R R + + R + E L
Sbjct: 1849 KENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDL 1908
Query: 692 KNAQAASWEMKRKQSLNF--VEECKVLTEDENTSDSDIILVSDKSNTDVSLKQEK----- 744
++ +AA+ ++ L F + + + EDE SD + L++ + ++DV + E
Sbjct: 1909 ESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGV 1968
Query: 745 KEIPLLNQEKQELCNDVLAMKRSSSLPSWKSL 776
K N+ + +D ++K SS WKSL
Sbjct: 1969 KSWLSKNKGPSKAASDDGSLKSSSPTSYWKSL 2000
Score = 30.4 bits (67), Expect = 8.5
Identities = 80/422 (18%), Positives = 173/422 (40%), Gaps = 43/422 (10%)
Query: 584 LTSAHKENTKTQKIRLLGDDLKHESLSSFELSASRRGQKRNIEETDSDVEYISETKIMKK 643
L+ AH+E Q+ +L + L+ E L A K+ +EE D D+ ++ + +
Sbjct: 1467 LSQAHEE---AQREKLQREKLQREKDM---LLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520
Query: 644 SMEEKMNSQQQRIPVALPENVKLAERSQRSQIANITTVWRAQP-TEGCLKNAQ-AASWEM 701
+ + ++SQ+ + +L + VK R +++ + Q T L+ A+ EM
Sbjct: 1521 AELQDISSQESKDEASLAK-VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM 1579
Query: 702 KRKQSLNFVEECKVLTEDENTSDSDIILVSDKSNTDVSLKQEKKEIPLLNQEKQELCNDV 761
+R + + E + + DE ++ +V L++E ++ + +EK+EL +
Sbjct: 1580 ERMRQTHSKE---MESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636
Query: 762 LAMKRSSSLPSWKSLLNVPMEDVNLSSGHIARVSVSGSCKVASSPASSQSTPVKETVRKL 821
+ + ++S + +D+ + +A + S P K + +L
Sbjct: 1637 ATLSDQVNRRDFESEKRL-RKDLKRTKALLADAQL-------MLDHLKNSAPSKREIAQL 1688
Query: 822 KSKLRE----ILLYFFPEHQLPSELEEPALS----CELEQCPEQMNKKLKMCFNQIQNTY 873
K++L E + E+E+ L + + E+ +L+ N+IQN
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748
Query: 874 MVQYE---KKIKRKLQSIIYDSNTRGIHNEI--SLGQCENKRKISEDKLKNLRIKLALLL 928
E + +K+ ++ S N++ L + +++ ++KL+ L+ ++ L
Sbjct: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1808
Query: 929 Q----KLQLGGPEGDLEQTDTYLEALLKEDNLL------FQNNLNKVTIDARHRLPLEKN 978
Q K + E + + +T LE + L + N+ K+T + R+ E
Sbjct: 1809 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENR 1868
Query: 979 EK 980
EK
Sbjct: 1869 EK 1870
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,969,668
Number of Sequences: 37866
Number of extensions: 1564209
Number of successful extensions: 6424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 187
Number of HSP's that attempted gapping in prelim test: 6096
Number of HSP's gapped (non-prelim): 540
length of query: 984
length of database: 18,247,518
effective HSP length: 112
effective length of query: 872
effective length of database: 14,006,526
effective search space: 12213690672
effective search space used: 12213690672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.