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Search of human proteins with 221316654
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo
sapiens]
(522 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 1065 0.0
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 858 0.0
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 855 0.0
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 410 e-114
gi|222080109 orexin receptor 2 [Homo sapiens] 197 2e-50
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 188 1e-47
gi|222080095 orexin receptor 1 [Homo sapiens] 187 2e-47
gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 186 3e-47
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 172 5e-43
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 167 3e-41
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 161 2e-39
gi|4502607 cholecystokinin A receptor [Homo sapiens] 158 1e-38
gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens] 156 5e-38
gi|157426873 tachykinin receptor 2 [Homo sapiens] 154 2e-37
gi|7669548 tachykinin receptor 3 [Homo sapiens] 154 2e-37
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 151 2e-36
gi|167000885 galanin receptor 1 [Homo sapiens] 145 9e-35
gi|4557857 somatostatin receptor 1 [Homo sapiens] 141 2e-33
gi|149944554 somatostatin receptor 4 [Homo sapiens] 141 2e-33
gi|5453666 G protein-coupled receptor 19 [Homo sapiens] 141 2e-33
gi|4557859 somatostatin receptor 2 [Homo sapiens] 139 6e-33
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 138 1e-32
gi|4557865 somatostatin receptor 5 [Homo sapiens] 136 5e-32
gi|4503905 galanin receptor 2 [Homo sapiens] 134 2e-31
gi|161484640 neuromedin B receptor [Homo sapiens] 133 5e-31
gi|62865887 G protein-coupled receptor 54 [Homo sapiens] 132 6e-31
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 132 8e-31
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 125 9e-29
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 125 9e-29
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 124 2e-28
>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
Length = 522
Score = 1065 bits (2755), Expect = 0.0
Identities = 522/522 (100%), Positives = 522/522 (100%)
Query: 1 MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRR 60
MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRR
Sbjct: 1 MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRR 60
Query: 61 LGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWN 120
LGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWN
Sbjct: 61 LGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWN 120
Query: 121 VNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHT 180
VNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHT
Sbjct: 121 VNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHT 180
Query: 181 VTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVA 240
VTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVA
Sbjct: 181 VTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVA 240
Query: 241 IAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQN 300
IAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQN
Sbjct: 241 IAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQN 300
Query: 301 KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKN 360
KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKN
Sbjct: 301 KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKN 360
Query: 361 QEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFA 420
QEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFA
Sbjct: 361 QEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFA 420
Query: 421 HWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQ 480
HWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQ
Sbjct: 421 HWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQ 480
Query: 481 LVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI 522
LVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
Sbjct: 481 LVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI 522
>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
Length = 423
Score = 858 bits (2218), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 101 FIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFL 160
FIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFL
Sbjct: 2 FIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFL 61
Query: 161 CMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMC 220
CMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMC
Sbjct: 62 CMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMC 121
Query: 221 KISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPS 280
KISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPS
Sbjct: 122 KISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPS 181
Query: 281 AVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIM 340
AVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIM
Sbjct: 182 AVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIM 241
Query: 341 YGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSD 400
YGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSD
Sbjct: 242 YGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSD 301
Query: 401 YADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAK 460
YADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAK
Sbjct: 302 YADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAK 361
Query: 461 PMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSS 520
PMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSS
Sbjct: 362 PMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSS 421
Query: 521 EI 522
EI
Sbjct: 422 EI 423
>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
Length = 420
Score = 855 bits (2208), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 103 MNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCM 162
MNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCM
Sbjct: 1 MNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCM 60
Query: 163 MGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKI 222
MGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKI
Sbjct: 61 MGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKI 120
Query: 223 SGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAV 282
SGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAV
Sbjct: 121 SGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAV 180
Query: 283 MLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYG 342
MLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYG
Sbjct: 181 MLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYG 240
Query: 343 RIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYA 402
RIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYA
Sbjct: 241 RIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYA 300
Query: 403 DLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPM 462
DLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPM
Sbjct: 301 DLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPM 360
Query: 463 EAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI 522
EAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
Sbjct: 361 EAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI 420
>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
Length = 430
Score = 410 bits (1054), Expect = e-114
Identities = 197/346 (56%), Positives = 262/346 (75%), Gaps = 3/346 (0%)
Query: 122 NDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTV 181
N T N+T+ +YY H VAA+FI++Y LIF LCM+GNT+VCFIV++N+HMHTV
Sbjct: 18 NGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRHMHTV 77
Query: 182 TNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAI 241
TN+FILNLA+SDLLVGIFCMP TL+DN+I GWPF N CK+SGLVQG+SV+ASVFTLVAI
Sbjct: 78 TNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAI 137
Query: 242 AVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNK 301
AV+RF+C+V+PF+ KLT++ A V I +IW LA+ IM PSAV L V E+++ ++++N+
Sbjct: 138 AVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHH-FMVDARNR 196
Query: 302 TSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQ 361
+ P+Y C E WP + MR++YTTVLF++IYLAPL+LIV+MY RI L +A P G +
Sbjct: 197 SYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPGGEEA 256
Query: 362 EQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAH 421
SR++ +++ ML++VAL F LSWLPLW L++L DY LS +L ++ +Y +PFAH
Sbjct: 257 ADPR-ASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAH 315
Query: 422 WLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQK-RAKPMEAYA 466
WLAF NSS NPIIYG+FNENFRRGFQ AF+ +LC + EAY+
Sbjct: 316 WLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYS 361
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 197 bits (501), Expect = 2e-50
Identities = 119/377 (31%), Positives = 190/377 (50%), Gaps = 39/377 (10%)
Query: 108 DTNSSENWHPIWNVNDTKHHLYSDINIT---YVNY----YLHQPQVAAIFIISYFLIFFL 160
D+ NW +N+T+ + + ++ Y YLH + + I Y ++F +
Sbjct: 8 DSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVV 67
Query: 161 CMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMC 220
++GN +VC V +N HM TVTN FI+NL+++D+LV I C+P TL+ +I W FG ++C
Sbjct: 68 ALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLC 127
Query: 221 KISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPS 280
K+ +Q +SV+ SV TL IA+DR+ + +P K T K A I+IIW+++ IM P
Sbjct: 128 KVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQ 187
Query: 281 AVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIM 340
A+++ V NKT+ C E W + K+Y F Y+APL L+V+
Sbjct: 188 AIVMECS-----TVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLA 242
Query: 341 YGRIGISLFRAAVPHTGRKNQEQWHVVS--------------------------RKKQKI 374
Y +I L+ +P T Q +W + R ++K
Sbjct: 243 YLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKT 302
Query: 375 IKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAFGNSSVNPI 433
+ML+IV L+F + +LP+ L +L + + +Y + F+HWL + NS+ NPI
Sbjct: 303 ARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPI 362
Query: 434 IYGFFNENFRRGFQEAF 450
IY F + FR F+ AF
Sbjct: 363 IYNFLSGKFREEFKAAF 379
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 188 bits (477), Expect = 1e-47
Identities = 105/322 (32%), Positives = 177/322 (54%), Gaps = 15/322 (4%)
Query: 151 IISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNII 210
+++ LIF L + GN +V ++V R+K M TVTN+FI +LA+SDLL+ FC+P+T+L NI
Sbjct: 49 VLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNIS 108
Query: 211 AGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK--LTIKTAFVIIMI 268
W G +CK+ VQ +V + T+ IAV+R Q +V+PFK K T + AF ++ +
Sbjct: 109 DNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGV 168
Query: 269 IWVLAITIMSPSAVMLHVQE-EKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFA 327
+W++A+ + SP M HVQ+ E Y ++ C E+W + +KIYTT +
Sbjct: 169 VWLVAVIVGSP---MWHVQQLEIKYDFLYEKEH-----ICCLEEWTSPVHQKIYTTFILV 220
Query: 328 NIYLAPLSLIVIMYGRIGISLFRAAVPHTGRK----NQEQWHVVSRKKQKIIKMLLIVAL 383
++L PL +++I+Y +IG L+ G + ++ ++RKK++ + M++ V
Sbjct: 221 ILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVA 280
Query: 384 LFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFR 443
LF + W P + M+ +Y++ + I+ + F NS NPI+Y F NENF+
Sbjct: 281 LFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFK 340
Query: 444 RGFQEAFQLQLCQKRAKPMEAY 465
+ A + K P + +
Sbjct: 341 KNVLSAVCYCIVNKTFSPAQRH 362
>gi|222080095 orexin receptor 1 [Homo sapiens]
Length = 425
Score = 187 bits (475), Expect = 2e-47
Identities = 115/352 (32%), Positives = 175/352 (49%), Gaps = 35/352 (9%)
Query: 129 YSDINITYV-NYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFIL 187
Y D + Y+ YL+ Q + I +Y +F + ++GNT+VC V RN HM TVTN FI+
Sbjct: 27 YEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIV 86
Query: 188 NLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQ 247
NL+++D+LV C+P +LL +I W FG+ +CK+ +Q +SV+ +V TL IA+DR+
Sbjct: 87 NLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWY 146
Query: 248 CVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYW 307
+ +P K T + A I+ IW +++ IM P A ++ V N+T
Sbjct: 147 AICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSS-----VLPELANRTRLFSV 201
Query: 308 CREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVV 367
C E W + KIY + F YLAPL L+ + Y +I L+ +P T W
Sbjct: 202 CDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRP 261
Query: 368 S----------------------------RKKQKIIKMLLIVALLFILSWLPLWTLMMLS 399
S R ++K KML++V L+F L +LP+ L +L
Sbjct: 262 SDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLK 321
Query: 400 DYADLSPNELQIINIY-IYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAF 450
+ +Y + F+HWL + NS+ NPIIY F + FR F+ AF
Sbjct: 322 RVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 373
>gi|223633971 G protein-coupled receptor 83 [Homo sapiens]
Length = 423
Score = 186 bits (473), Expect = 3e-47
Identities = 108/322 (33%), Positives = 168/322 (52%), Gaps = 20/322 (6%)
Query: 144 PQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPI 203
P V A+ I++Y I + GN +VC ++ +N+ MH+ T+LFI+NLA++D+++ + P
Sbjct: 68 PTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPF 127
Query: 204 TLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAF 263
TL+ + + W FG MC +S Q S+ S TL AIAVDR Q +++P KP+++I
Sbjct: 128 TLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGV 187
Query: 264 VIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQE--MRKIY 321
+ I +IW +A P A+ + KY + S C D+P K
Sbjct: 188 IYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRS--------LCLPDFPEPADLFWKYL 239
Query: 322 TTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIV 381
F +Y+ PL +I + Y R+ L+ + G EQ+ + RKK+K IKML++V
Sbjct: 240 DLATFILLYILPLLIISVAYARVAKKLWLCNM--IGDVTTEQYFALRRKKKKTIKMLMLV 297
Query: 382 ALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNEN 441
+LF L W PL ++L LS ++ N + F HW A ++ NP IY + NEN
Sbjct: 298 VVLFALCWFPLNCYVLL-----LSSKVIRTNNALYFAF-HWFAMSSTCYNPFIYCWLNEN 351
Query: 442 FRRGFQEAFQLQLCQKRAKPME 463
FR + L +CQ+ KP E
Sbjct: 352 FR--IELKALLSMCQRPPKPQE 371
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 172 bits (437), Expect = 5e-43
Identities = 104/346 (30%), Positives = 181/346 (52%), Gaps = 35/346 (10%)
Query: 145 QVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPIT 204
+V + I++Y I L ++GN++V +V++ K M TVTN FI NLA++DLLV C+P T
Sbjct: 48 EVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFT 107
Query: 205 LLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFV 264
L ++ W G +C + QG++V S TL IA+DR +C+VY + K++ + +F+
Sbjct: 108 LTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFL 167
Query: 265 IIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTV 324
II + W ++ + SP A+ +Y + + + + C E WP +E + IY TV
Sbjct: 168 IIGLAWGISALLASPLAIF-----REYSLIEIIPDFE---IVACTEKWPGEE-KSIYGTV 218
Query: 325 LFAN----IYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLI 380
+ +Y+ PL +I Y RI L P + Q ++QK KML+
Sbjct: 219 YSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQ------RRQKTTKMLVC 272
Query: 381 VALLFILSWLPLWTLMMLSDYADLSPNELQIINI----YIYPFAHWLAFGNSSVNPIIYG 436
V ++F +SWLPL + D + Q++++ I+ H +A ++ NP++YG
Sbjct: 273 VVVVFAVSWLPLHAFQLAVDI------DSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYG 326
Query: 437 FFNENFRRGFQEAFQLQLCQKRAKPME---AYALKAKSHVLINTSN 479
+ N N+R+ F AF+ C++R + + KAK ++ + ++
Sbjct: 327 WMNSNYRKAFLSAFR---CEQRLDAIHSEVSVTFKAKKNLEVRKNS 369
>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
Length = 384
Score = 167 bits (422), Expect = 3e-41
Identities = 114/349 (32%), Positives = 180/349 (51%), Gaps = 26/349 (7%)
Query: 122 NDTKHHLYSDIN---ITYVNYYLHQPQVAAIFIIS--YFLIFFLCMMGNTVVCFIVMRNK 176
N + H +S+ N + + N H P +A IF ++ Y + L + GN + I+++ K
Sbjct: 11 NHSVHSNFSEKNAQLLAFENDDCHLP-LAMIFTLALAYGAVIILGVSGNLALIIIILKQK 69
Query: 177 HMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVF 236
M VTN+ I+NL+ SDLLV I C+P T + ++ W FG MCK++ VQ +S+ S+F
Sbjct: 70 EMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIF 129
Query: 237 TLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRL 296
+LV IAV+R Q ++ P + + A+V I +IWVLA+ P + + +E + V L
Sbjct: 130 SLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTL 189
Query: 297 NSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAA-VPH 355
++ Y C + +P+ R YTT+L Y PL I I Y +I I L R +
Sbjct: 190 DAYKDK---YVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMD 246
Query: 356 TGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQII--- 412
R N+ + S + ++I MLL + + F + WLPL + D+ QII
Sbjct: 247 KMRDNKYR----SSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNH------QIIATC 296
Query: 413 -NIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAK 460
+ ++ H A ++ VNPI YGF N+NF+R Q F C R++
Sbjct: 297 NHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQ--FFFNFCDFRSR 343
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 161 bits (407), Expect = 2e-39
Identities = 91/302 (30%), Positives = 163/302 (53%), Gaps = 19/302 (6%)
Query: 145 QVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPIT 204
Q+ + ++ Y ++ + ++GN ++ ++ R + +H VTN I NLA+SD+L+ C+P+T
Sbjct: 58 QLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLT 117
Query: 205 LLDNIIA-GWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAF 263
L GW FG +C + +Q ++V SVFTL IAVDR+ +V+P + +++++ +
Sbjct: 118 LAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSA 177
Query: 264 VIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQE-MRKIYT 322
++ IW L+ + P+AV + E K + VRL C E W +QE R++Y
Sbjct: 178 YAVLAIWALSAVLALPAAVHTYHVELKPHDVRL-----------CEEFWGSQERQRQLYA 226
Query: 323 TVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVA 382
L YL PL +I++ Y R+ + L VP ++Q W ++++ +L++V
Sbjct: 227 WGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWD--RARRRRTFCLLVVVV 284
Query: 383 LLFILSWLPLWTLMMLSDYADLSPNELQIINI-YIYPFAHWLAFGNSSVNPIIYGFFNEN 441
++F + WLPL +L DL P+ + + HWLA ++ NP IY + +++
Sbjct: 285 VVFAVCWLPLHVFNLL---RDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDS 341
Query: 442 FR 443
FR
Sbjct: 342 FR 343
>gi|4502607 cholecystokinin A receptor [Homo sapiens]
Length = 428
Score = 158 bits (399), Expect = 1e-38
Identities = 102/356 (28%), Positives = 176/356 (49%), Gaps = 65/356 (18%)
Query: 148 AIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLD 207
A+ I+ Y LIF L ++GNT+V +++RNK M TVTN+F+L+LA+SDL++ +FCMP L+
Sbjct: 42 AVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIP 101
Query: 208 NIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKL--TIKTAFVI 265
N++ + FG+ +CK + G SV+ S F LVAI+++R+ + P + ++ T A +
Sbjct: 102 NLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKV 161
Query: 266 IMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVL 325
I W L+ TIM+P + Y + ++N CR PN M++ + T L
Sbjct: 162 IAATWCLSFTIMTPYPI--------YSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFL 213
Query: 326 FANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRK-------------------------- 359
++L P ++++ YG I + L++ +K
Sbjct: 214 LLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQK 273
Query: 360 -------------------------NQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWT 394
N +++++K ++I+ML+++ +LF L W+P+++
Sbjct: 274 TRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKK--RVIRMLIVIVVLFFLCWMPIFS 331
Query: 395 LMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAF 450
Y D + E ++ I F L++ +S VNPIIY F N+ FR GF F
Sbjct: 332 ANAWRAY-DTASAERRLSGTPI-SFILLLSYTSSCVNPIIYCFMNKRFRLGFMATF 385
>gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]
Length = 375
Score = 156 bits (394), Expect = 5e-38
Identities = 108/347 (31%), Positives = 172/347 (49%), Gaps = 14/347 (4%)
Query: 146 VAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITL 205
V + SY + + ++GN + + +R K VTNL I NLA SD L+ + C P+T
Sbjct: 40 VMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTA 99
Query: 206 LDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVI 265
+ I+ W FG T+CK+S +Q +SV S+ +LV +A++R Q ++ P K +I A++
Sbjct: 100 VYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLG 159
Query: 266 IMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVL 325
I++IWV+A + P + + E +++ + + C E WP R IYTT L
Sbjct: 160 IVLIWVIACVLSLP-FLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFL 218
Query: 326 FANIYLAPLSLIVIMYGRIGISLFR-AAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALL 384
Y PL I++ Y RI L R V H G + H+ K+ ++ ++++VA
Sbjct: 219 LLFQYCLPLGFILVCYARIYRRLQRQGRVFHKGTYSLRAGHM---KQVNVVLVVMVVA-- 273
Query: 385 FILSWLPLWTLMMLSDYADLSPNELQIIN-IYIYPFAHWLAFGNSSVNPIIYGFFNENFR 443
F + WLPL L D+ + I + I+ H LA ++ VNP IYGF N NF+
Sbjct: 274 FAVLWLPLHVFNSLEDW---HHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFK 330
Query: 444 RGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNP 490
+ E L L +++ P+E S V S ++ S NP
Sbjct: 331 K---EIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNP 374
>gi|157426873 tachykinin receptor 2 [Homo sapiens]
Length = 398
Score = 154 bits (389), Expect = 2e-37
Identities = 92/307 (29%), Positives = 153/307 (49%), Gaps = 20/307 (6%)
Query: 148 AIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLD 207
A++ +Y + + + GN +V +I++ ++ M TVTN FI+NLA++DL + F +
Sbjct: 34 ALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVY 93
Query: 208 NIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIM 267
W FG C L ++ S++++ AIA DR+ +V+PF+P+L+ + +I
Sbjct: 94 ASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIA 153
Query: 268 IIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRK---IYTTV 324
IW++A+ + SP +Y Q T C WP K +Y V
Sbjct: 154 GIWLVALALASPQC---------FYSTVTMDQGATK----CVVAWPEDSGGKTLLLYHLV 200
Query: 325 LFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALL 384
+ A IY PL+++ + Y IG++L+R AVP H+ + K K +K +++V L
Sbjct: 201 VIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMK--KFVKTMVLVVLT 258
Query: 385 FILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR 444
F + WLP +L + + I +Y+ F WLA ++ NPIIY N FR
Sbjct: 259 FAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALF--WLAMSSTMYNPIIYCCLNHRFRS 316
Query: 445 GFQEAFQ 451
GF+ AF+
Sbjct: 317 GFRLAFR 323
>gi|7669548 tachykinin receptor 3 [Homo sapiens]
Length = 465
Score = 154 bits (389), Expect = 2e-37
Identities = 90/316 (28%), Positives = 159/316 (50%), Gaps = 21/316 (6%)
Query: 138 NYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVG 197
N ++ A++ ++Y ++ + ++GN +V +I++ +K M TVTN F++NLA SD +
Sbjct: 76 NQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMA 135
Query: 198 IFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKL 257
F + + + + W FG C+ +V AS++++ AIAVDR+ ++ P KP+L
Sbjct: 136 AFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRL 195
Query: 258 TIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSP-VYWCREDWP-NQ 315
+ ++I IW+LA + P L S+ K P C WP
Sbjct: 196 SATATKIVIGSIWILAFLLAFPQC--------------LYSKTKVMPGRTLCFVQWPEGP 241
Query: 316 EMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKII 375
+ Y ++ +Y PL ++ I Y +GI+L+ +P +++H + K+K++
Sbjct: 242 KQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIP---GDTCDKYHEQLKAKRKVV 298
Query: 376 KMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIY 435
KM++IV + F + WLP +L+ I +Y+ F WLA ++ NPIIY
Sbjct: 299 KMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASF--WLAMSSTMYNPIIY 356
Query: 436 GFFNENFRRGFQEAFQ 451
N+ FR GF+ AF+
Sbjct: 357 CCLNKRFRAGFKRAFR 372
>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
Length = 407
Score = 151 bits (381), Expect = 2e-36
Identities = 92/324 (28%), Positives = 164/324 (50%), Gaps = 25/324 (7%)
Query: 133 NITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAIS 192
N + N ++ ++ +Y +I ++GN VV +I++ +K M TVTN F++NLA +
Sbjct: 18 NTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFA 77
Query: 193 DLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYP 252
+ + F + + W +G CK +V AS++++ A+A DR+ +++P
Sbjct: 78 EASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHP 137
Query: 253 FKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPV-YWCRED 311
+P+L+ V+I +IWVLA+ + P + YY S +T P C +
Sbjct: 138 LQPRLSATATKVVICVIWVLALLLAFP---------QGYY-----STTETMPSRVVCMIE 183
Query: 312 W---PNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS 368
W PN+ K+Y + IY PL +I Y +GI+L+ + +P + +++H
Sbjct: 184 WPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIP---GDSSDRYHEQV 240
Query: 369 RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPN-ELQIINIYIYPFAHWLAFGN 427
K+K++KM+++V F + WLP +L ++P+ L+ +Y WLA +
Sbjct: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLL---PYINPDLYLKKFIQQVYLAIMWLAMSS 297
Query: 428 SSVNPIIYGFFNENFRRGFQEAFQ 451
+ NPIIY N+ FR GF+ AF+
Sbjct: 298 TMYNPIIYCCLNDRFRLGFKHAFR 321
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 145 bits (366), Expect = 9e-35
Identities = 93/310 (30%), Positives = 157/310 (50%), Gaps = 26/310 (8%)
Query: 149 IFIISYFLIFFLCMMGNTVVCFIVMRNK--HMHTVTNLFILNLAISDLLVGIFCMPITLL 206
+ ++ + LIF L ++GN++V ++ R+K + TNLFILNL+I+DL +FC+P
Sbjct: 35 VTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQAT 94
Query: 207 DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK--LTIKTAFV 264
+ W G +CK +S+ S+FTL A++VDR+ +V+ + + A +
Sbjct: 95 VYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALL 154
Query: 265 IIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTV 324
+ IW L+I + SP A + + R ++Q +C E WP+ +K Y
Sbjct: 155 GVGCIWALSIAMASPVA-----YHQGLFHPRASNQT------FCWEQWPDPRHKKAYVVC 203
Query: 325 LFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALL 384
F YL PL LI Y ++ + H +K + K+K + +L+V ++
Sbjct: 204 TFVFGYLLPLLLICFCYAKV--------LNHLHKKLKNMSKKSEASKKKTAQTVLVVVVV 255
Query: 385 FILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR 444
F +SWLP + + +A+ L + AH LA+ NSSVNPIIY F +ENFR+
Sbjct: 256 FGISWLPHHIIHL---WAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRK 312
Query: 445 GFQEAFQLQL 454
+++ F+ +
Sbjct: 313 AYKQVFKCHI 322
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 141 bits (355), Expect = 2e-33
Identities = 96/343 (27%), Positives = 174/343 (50%), Gaps = 39/343 (11%)
Query: 138 NYYLHQPQVAAIFI-ISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLV 196
N L + Q +AI I Y ++ + + GN++V ++++R M T TN++ILNLAI+D L+
Sbjct: 48 NGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELL 107
Query: 197 GIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK 256
+ +P + ++ WPFG +C++ V +++ S++ L ++VDR+ VV+P K
Sbjct: 108 -MLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAA 166
Query: 257 LTIK--TAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPN 314
+ A V+ + +WVL++ ++ P V + R NS + C P
Sbjct: 167 RYRRPTVAKVVNLGVWVLSLLVILPIVV--------FSRTAANSDGTVA----CNMLMPE 214
Query: 315 QEMRKIYTTVLFANI--YLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQ 372
R + VL+ + +L P+ I + Y I I+ R G W R ++
Sbjct: 215 PAQRWLVGFVLYTFLMGFLLPVGAICLCYVLI-IAKMRMVALKAG------WQQRKRSER 267
Query: 373 KIIKMLLIVALLFILSWLPLWTLMMLSDYA---DLSPNELQIINIYIYPFAHWLAFGNSS 429
KI M+++V ++F++ W+P + + +++ +A D + ++L +I L + NS
Sbjct: 268 KITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVI----------LGYANSC 317
Query: 430 VNPIIYGFFNENFRRGFQEAFQLQLCQKRA-KPMEAYALKAKS 471
NPI+YGF ++NF+R FQ L A +P++ YA KS
Sbjct: 318 ANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS 360
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 141 bits (355), Expect = 2e-33
Identities = 88/329 (26%), Positives = 160/329 (48%), Gaps = 40/329 (12%)
Query: 154 YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGW 213
Y L+ + ++GN +V F+++R M T TN+++LNLA++D L + +P + W
Sbjct: 54 YALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELF-MLSVPFVASSAALRHW 112
Query: 214 PFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIK--TAFVIIMIIWV 271
PFG+ +C+ V G+++ SVF L ++VDR+ VV+P + + A +I + +W+
Sbjct: 113 PFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWL 172
Query: 272 LAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYL 331
++ + P A+ + + C WP+ ++ F +L
Sbjct: 173 ASLLVTLPIAIFADTRPA-----------RGGQAVACNLQWPHPAWSAVFVVYTFLLGFL 221
Query: 332 APLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLP 391
P+ I + Y I + RA G W R ++KI +++L+V ++F+L W+P
Sbjct: 222 LPVLAIGLCYLLI-VGKMRAVALRAG------WQQRRRSEKKITRLVLMVVVVFVLCWMP 274
Query: 392 LWTLMMLSDYA---DLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQE 448
+ + +L+ + D + N + +I L++ NS NPI+YGF ++NFRR FQ
Sbjct: 275 FYVVQLLNLFVTSLDATVNHVSLI----------LSYANSCANPILYGFLSDNFRRFFQR 324
Query: 449 AFQLQLC------QKRAKPMEAYALKAKS 471
L+ C +P++ YA KS
Sbjct: 325 VLCLRCCLLEGAGGAEEEPLDYYATALKS 353
>gi|5453666 G protein-coupled receptor 19 [Homo sapiens]
Length = 415
Score = 141 bits (355), Expect = 2e-33
Identities = 83/313 (26%), Positives = 152/313 (48%), Gaps = 25/313 (7%)
Query: 139 YYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGI 198
+Y+ +P A I + +++ + GN++VC ++ R++ + TN F++++A +DLL+ +
Sbjct: 57 HYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISV 116
Query: 199 FCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLT 258
P LL W G+ CK+ Q ++ ++ L++I +DRF +VYP K++
Sbjct: 117 ASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVS 176
Query: 259 IKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMR 318
+ A +I W+ ++P +Y +S C P+
Sbjct: 177 REKAKKMIAASWIFDAGFVTPVLF--------FYGSNWDSH--------CNYFLPSSWEG 220
Query: 319 KIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKML 378
YT + F ++ P LI++ Y ++ ++R + GR + ++V R K K IKM
Sbjct: 221 TAYTVIHFLVGFVIPSVLIILFYQKVIKYIWR--IGTDGRTVRRTMNIVPRTKVKTIKMF 278
Query: 379 LIVALLFILSWLPLWTLMMLSDY-ADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGF 437
LI+ LLF+LSWLP + + D + L ++ W++F +S+ P +Y
Sbjct: 279 LILNLLFLLSWLPFHVAQLWHPHEQDYKKSSL------VFTAITWISFSSSASKPTLYSI 332
Query: 438 FNENFRRGFQEAF 450
+N NFRRG +E F
Sbjct: 333 YNANFRRGMKETF 345
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 139 bits (350), Expect = 6e-33
Identities = 86/309 (27%), Positives = 157/309 (50%), Gaps = 27/309 (8%)
Query: 148 AIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLD 207
A+ YF++ + + GNT+V ++++R M T+TN++ILNLAI+D L + +P +
Sbjct: 44 AVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELF-MLGLPFLAMQ 102
Query: 208 NIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK--LTIKTAFVI 265
+ WPFG +C++ V GI+ S+F L +++DR+ VV+P K +TA +I
Sbjct: 103 VALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMI 162
Query: 266 IMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVL 325
M +W +++ ++ P + Y +R N ++S C +WP + ++
Sbjct: 163 TMAVWGVSLLVILPIMI--------YAGLRSNQWGRSS----CTINWPGESGAWYTGFII 210
Query: 326 FANI--YLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVAL 383
+ I +L PL++I + Y I I + + + K + + ++K+ +M+ IV
Sbjct: 211 YTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRK-------KSEKKVTRMVSIVVA 263
Query: 384 LFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFR 443
+FI WLP + + S +SP ++ F L + NS NPI+Y F ++NF+
Sbjct: 264 VFIFCWLPFYIFNVSSVSMAISPTPAL---KGMFDFVVVLTYANSCANPILYAFLSDNFK 320
Query: 444 RGFQEAFQL 452
+ FQ L
Sbjct: 321 KSFQNVLCL 329
>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
Length = 311
Score = 138 bits (348), Expect = 1e-32
Identities = 86/313 (27%), Positives = 156/313 (49%), Gaps = 25/313 (7%)
Query: 133 NITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAIS 192
N + N ++ ++ +Y +I ++GN VV +I++ +K M TVTN F++NLA +
Sbjct: 18 NTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFA 77
Query: 193 DLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYP 252
+ + F + + W +G CK +V AS++++ A+A DR+ +++P
Sbjct: 78 EASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHP 137
Query: 253 FKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPV-YWCRED 311
+P+L+ V+I +IWVLA+ + P + YY S +T P C +
Sbjct: 138 LQPRLSATATKVVICVIWVLALLLAFP---------QGYY-----STTETMPSRVVCMIE 183
Query: 312 W---PNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS 368
W PN+ K+Y + IY PL +I Y +GI+L+ + +P + +++H
Sbjct: 184 WPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIP---GDSSDRYHEQV 240
Query: 369 RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPN-ELQIINIYIYPFAHWLAFGN 427
K+K++KM+++V F + WLP +L ++P+ L+ +Y WLA +
Sbjct: 241 SAKRKVVKMMIVVVCTFAICWLPFHIFFLL---PYINPDLYLKKFIQQVYLAIMWLAMSS 297
Query: 428 SSVNPIIYGFFNE 440
+ NPIIY N+
Sbjct: 298 TMYNPIIYCCLND 310
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 136 bits (342), Expect = 5e-32
Identities = 103/344 (29%), Positives = 163/344 (47%), Gaps = 38/344 (11%)
Query: 117 PIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNK 176
P WN + N T V A + + Y L+ + GNT+V ++V+R
Sbjct: 10 PSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFA 69
Query: 177 HMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVF 236
M TVTN++ILNLA++D+L + +P N + WPFG +C++ + G++ SVF
Sbjct: 70 KMKTVTNIYILNLAVADVLY-MLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVF 128
Query: 237 TLVAIAVDRFQCVVYPFKPK--LTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRV 294
L ++VDR+ VV+P + A + WVL++ + P V VQE
Sbjct: 129 CLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGG---- 184
Query: 295 RLNSQNKTSPVYWCREDWPNQ-----EMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLF 349
C WP + IYT VL + APL +I + Y I + +
Sbjct: 185 ------------TCNASWPEPVGLWGAVFIIYTAVLG---FFAPLLVICLCYLLIVVKV- 228
Query: 350 RAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNEL 409
RAA G V R ++K+ +M+L+V L+F WLP +T+ ++ + A P E
Sbjct: 229 RAAGVRVG-------CVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIV-NLAVALPQEP 280
Query: 410 QIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQ 453
+Y F L++ NS NP++YGF ++NFR+ FQ+ L+
Sbjct: 281 ASAGLYF--FVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLR 322
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 134 bits (337), Expect = 2e-31
Identities = 89/303 (29%), Positives = 149/303 (49%), Gaps = 25/303 (8%)
Query: 147 AAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLL 206
A I + + LIF + +GNT+V +++R + TNLFILNL ++DL + C+P
Sbjct: 25 AVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQAT 84
Query: 207 DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK--LTIKTAFV 264
+ GW FG+ +CK + +++ AS FTL A+++DR+ + YP + T + A
Sbjct: 85 IYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALA 144
Query: 265 IIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTV 324
I +IW L++ P YYR Q++ + + C W + R+
Sbjct: 145 AIGLIWGLSLLFSGPYL--------SYYR-----QSQLANLTVCHPAW-SAPRRRAMDIC 190
Query: 325 LFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALL 384
F YL P+ ++ + Y R L+RA P R K+K+ +M+LIVA L
Sbjct: 191 TFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSG------ARRAKRKVTRMILIVAAL 244
Query: 385 FILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR 444
F L W+P L++ + L + +H +++ NS VNPI+Y +++FR+
Sbjct: 245 FCLCWMPHHALILCVWFGQF---PLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRK 301
Query: 445 GFQ 447
GF+
Sbjct: 302 GFR 304
>gi|161484640 neuromedin B receptor [Homo sapiens]
Length = 390
Score = 133 bits (334), Expect = 5e-31
Identities = 102/348 (29%), Positives = 168/348 (48%), Gaps = 25/348 (7%)
Query: 154 YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGW 213
Y LI + ++GN ++ I + N M +V N+FI NLA DLL+ + C+P+ W
Sbjct: 50 YLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEW 109
Query: 214 PFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLT--IKTAFVIIMIIWV 271
FG CK+ ++Q SV SVFTL A++ DR++ +V P + + + V M IWV
Sbjct: 110 MFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWV 169
Query: 272 LAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYL 331
+++ + P AV V R++S + +S ++ KI++ ++F +L
Sbjct: 170 VSVLLAVPEAVFSEV-------ARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFL 222
Query: 332 APLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLP 391
PL++I I Y I +L ++A G N+ + +K ++ K++L+ FI W P
Sbjct: 223 IPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRK-RLAKIVLVFVGCFIFCWFP 281
Query: 392 LWTLMMLSDYADLSPNEL--QIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEA 449
L M Y + NE+ + ++ + A L+FGNS VNP +E+FRR F
Sbjct: 282 NHILYM---YRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNS- 337
Query: 450 FQLQLCQKRAKPME---AYALKA---KSHVLINTSNQLVQESTFQNPH 491
QLC R E +Y L + + L + + +V S N H
Sbjct: 338 ---QLCCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGH 382
>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
Length = 398
Score = 132 bits (333), Expect = 6e-31
Identities = 85/313 (27%), Positives = 156/313 (49%), Gaps = 23/313 (7%)
Query: 144 PQVAAIFIISYFL--IFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCM 201
P+ +++ F + L ++GN++V +++ R+K M TVTN +I NLA +D+ + C+
Sbjct: 37 PRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCV 96
Query: 202 PITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKP--KLTI 259
P T L + GW G+ MCK +Q +SV A+ TL A++VDR+ V+P + + T
Sbjct: 97 PFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTP 156
Query: 260 KTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRK 319
+ A + + IWV + + +P + LH RL+ P +C E +P++ + +
Sbjct: 157 RLALAVSLSIWVGSAAVSAP-VLALH---------RLS----PGPRAYCSEAFPSRALER 202
Query: 320 IYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRK----KQKII 375
+ +YL PL Y + L R AV + Q V++ + + K+
Sbjct: 203 AFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVS 262
Query: 376 KMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIY-IYPFAHWLAFGNSSVNPII 434
+++ V LLF W P+ ++L + Y + +AH +++ NS++NP++
Sbjct: 263 RLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLL 322
Query: 435 YGFFNENFRRGFQ 447
Y F +FR+ F+
Sbjct: 323 YAFLGSHFRQAFR 335
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 132 bits (332), Expect = 8e-31
Identities = 85/314 (27%), Positives = 159/314 (50%), Gaps = 16/314 (5%)
Query: 152 ISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIA 211
I+Y +I + ++GN ++ + + K M TV N+FI +LA DLL+ + C+P+ +
Sbjct: 52 ITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAE 111
Query: 212 GWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPF--KPKLTIKTAFVIIMII 269
GW FG CK+ ++ SV SVFTL ++ DR++ VV P +P I V +
Sbjct: 112 GWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCV 171
Query: 270 WVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTS-PVYWCREDWPNQEMRKIYTTVLFAN 328
W++++ P A+ +V + + ++ TS PV + +++I++ + F
Sbjct: 172 WIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPV-------SKKLLQEIHSLLCFLV 224
Query: 329 IYLAPLSLIVIMYGRIGISLFRAAVP-HTGRKNQEQWHVVSRKKQKIIKMLLIVALLFIL 387
Y+ PLS+I + Y I +L+++ + T ++ + + SRK +I + +L++ LF L
Sbjct: 225 FYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRK--RIARTVLVLVALFAL 282
Query: 388 SWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQ 447
WLP L + + + + ++ F+ LAF NS VNP + +++F++ F+
Sbjct: 283 CWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFK 342
Query: 448 EAFQLQLCQKRAKP 461
C K +P
Sbjct: 343 AQL---FCCKAERP 353
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 125 bits (314), Expect = 9e-29
Identities = 87/307 (28%), Positives = 149/307 (48%), Gaps = 24/307 (7%)
Query: 156 LIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPF 215
++ + + GN VVC V N+ + +TN FI++LAI+DLL+G+ +P + + + W F
Sbjct: 27 VLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSF 86
Query: 216 GNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVII--MIIWVLA 273
G C I + + AS+ L I++DR+ V+ P + + + V I ++IWV++
Sbjct: 87 GKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVIS 146
Query: 274 ITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAP 333
IT+ S + +H + NS+N+TS Q + ++Y V + P
Sbjct: 147 ITL---SFLSIH--------LGWNSRNETSKGNHTTSKCKVQ-VNEVYGLVDGLVTFYLP 194
Query: 334 LSLIVIMYGRIGISLFRAAVPHTGRKNQ-EQWHVVSRKKQKIIKMLLIVALLFILSWLPL 392
L ++ I Y RI F+ A R N W + ++ K L V FI+ W P
Sbjct: 195 LLIMCITYYRI----FKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPY 250
Query: 393 WTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQL 452
+T + Y L ++ IN + WL + NS++NPI+Y N +FR G+Q+ F
Sbjct: 251 FTAFV---YRGLRGDD--AINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCC 305
Query: 453 QLCQKRA 459
+L + +
Sbjct: 306 RLANRNS 312
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 125 bits (314), Expect = 9e-29
Identities = 87/307 (28%), Positives = 149/307 (48%), Gaps = 24/307 (7%)
Query: 156 LIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPF 215
++ + + GN VVC V N+ + +TN FI++LAI+DLL+G+ +P + + + W F
Sbjct: 27 VLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSF 86
Query: 216 GNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVII--MIIWVLA 273
G C I + + AS+ L I++DR+ V+ P + + + V I ++IWV++
Sbjct: 87 GKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVIS 146
Query: 274 ITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAP 333
IT+ S + +H + NS+N+TS Q + ++Y V + P
Sbjct: 147 ITL---SFLSIH--------LGWNSRNETSKGNHTTSKCKVQ-VNEVYGLVDGLVTFYLP 194
Query: 334 LSLIVIMYGRIGISLFRAAVPHTGRKNQ-EQWHVVSRKKQKIIKMLLIVALLFILSWLPL 392
L ++ I Y RI F+ A R N W + ++ K L V FI+ W P
Sbjct: 195 LLIMCITYYRI----FKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPY 250
Query: 393 WTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQL 452
+T + Y L ++ IN + WL + NS++NPI+Y N +FR G+Q+ F
Sbjct: 251 FTAFV---YRGLRGDD--AINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCC 305
Query: 453 QLCQKRA 459
+L + +
Sbjct: 306 RLANRNS 312
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 124 bits (311), Expect = 2e-28
Identities = 92/355 (25%), Positives = 180/355 (50%), Gaps = 32/355 (9%)
Query: 111 SSENWHPIWNVNDTKHHLYSD---INITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTV 167
+S W P W D+ S+ + +++ P + I Y ++F + ++GN++
Sbjct: 25 NSSAWFPGWAEPDSNGSAGSEDAQLEPAHIS-----PAIPVIITAVYSVVFVVGLVGNSL 79
Query: 168 VCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQ 227
V F+++R M T TN++I NLA++D LV MP ++ WPFG+ +CKI +
Sbjct: 80 VMFVIIRYTKMKTATNIYIFNLALADALV-TTTMPFQSTVYLMNSWPFGDVLCKIVISID 138
Query: 228 GISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKT---AFVIIMIIWVLAITIMSPSAVML 284
++ S+FTL ++VDR+ V +P K L +T A +I + IW+L+ ++ SA++L
Sbjct: 139 YYNMFTSIFTLTMMSVDRYIAVCHPVK-ALDFRTPLKAKIINICIWLLSSSV-GISAIVL 196
Query: 285 HVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRI 344
+VR + + + +D+ ++ +FA ++ P+ +I++ Y +
Sbjct: 197 GGT-----KVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFA--FVIPVLIIIVCYTLM 249
Query: 345 GISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADL 404
+ L + R+ R ++I +++L+V +F++ W P+ +++
Sbjct: 250 ILRLKSVRLLSGSREK-------DRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGST 302
Query: 405 SPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQE-AFQLQLCQKR 458
S + + + Y F L + NSS+NPI+Y F +ENF+R F++ F L++ +R
Sbjct: 303 SHSTAALSSYY---FCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMER 354
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,651,242
Number of Sequences: 37866
Number of extensions: 779544
Number of successful extensions: 4240
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 512
Number of HSP's successfully gapped in prelim test: 176
Number of HSP's that attempted gapping in prelim test: 2819
Number of HSP's gapped (non-prelim): 910
length of query: 522
length of database: 18,247,518
effective HSP length: 107
effective length of query: 415
effective length of database: 14,195,856
effective search space: 5891280240
effective search space used: 5891280240
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.