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Search of human proteins with 221219053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7
isoform 1 [Homo sapiens]
(494 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 1003 0.0
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 890 0.0
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 180 2e-45
gi|201862587 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform... 92 1e-18
gi|201862518 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform... 92 1e-18
gi|56549115 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform ... 92 1e-18
gi|6631085 DnaJ (Hsp40) homolog, subfamily B, member 4 [Homo sap... 90 4e-18
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 89 9e-18
gi|17388799 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform ... 89 9e-18
gi|4885495 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b... 89 9e-18
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 87 3e-17
gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo sap... 87 3e-17
gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 87 3e-17
gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 86 6e-17
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 86 6e-17
gi|47777312 DnaJ (Hsp40) homolog, subfamily B, member 3 [Homo sa... 84 2e-16
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 84 4e-16
gi|23503241 DnaJ homolog, subfamily B, member 8 [Homo sapiens] 82 1e-15
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 79 7e-15
gi|194306642 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo ... 79 7e-15
gi|194306640 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo ... 79 7e-15
gi|5453690 DnaJ (Hsp40) homolog, subfamily B, member 1 [Homo sap... 77 3e-14
gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo s... 76 8e-14
gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 75 1e-13
gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 75 1e-13
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 75 1e-13
gi|72534740 DnaJ (Hsp40) homolog, subfamily B, member 14 isoform... 75 2e-13
gi|21553335 DnaJ (Hsp40) homolog, subfamily B, member 7 [Homo sa... 74 2e-13
gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precurso... 74 3e-13
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 73 7e-13
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 1003 bits (2594), Expect = 0.0
Identities = 494/494 (100%), Positives = 494/494 (100%)
Query: 1 MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPK 60
MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPK
Sbjct: 1 MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPK 60
Query: 61 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ 120
NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ
Sbjct: 61 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ 120
Query: 121 RALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKI 180
RALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKI
Sbjct: 121 RALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKI 180
Query: 181 LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMA 240
LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMA
Sbjct: 181 LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMA 240
Query: 241 PDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNR 300
PDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNR
Sbjct: 241 PDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNR 300
Query: 301 GTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKT 360
GTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKT
Sbjct: 301 GTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKT 360
Query: 361 KEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEV 420
KEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEV
Sbjct: 361 KEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEV 420
Query: 421 QKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFS 480
QKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFS
Sbjct: 421 QKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFS 480
Query: 481 FEASGPGNFFFQFG 494
FEASGPGNFFFQFG
Sbjct: 481 FEASGPGNFFFQFG 494
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 890 bits (2300), Expect = 0.0
Identities = 437/438 (99%), Positives = 438/438 (100%)
Query: 57 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC 116
MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC
Sbjct: 1 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC 60
Query: 117 RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH 176
RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH
Sbjct: 61 RSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACH 120
Query: 177 RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA 236
RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA
Sbjct: 121 RFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQA 180
Query: 237 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 296
LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL
Sbjct: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240
Query: 297 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 356
YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ
Sbjct: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300
Query: 357 TEKTKEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA 416
TEKTKEHKQLLKNAQLEL+KSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA
Sbjct: 301 TEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGA 360
Query: 417 SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP 476
SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP
Sbjct: 361 SAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGP 420
Query: 477 GGFSFEASGPGNFFFQFG 494
GGFSFEASGPGNFFFQFG
Sbjct: 421 GGFSFEASGPGNFFFQFG 438
Score = 40.4 bits (93), Expect = 0.004
Identities = 58/299 (19%), Positives = 114/299 (38%), Gaps = 32/299 (10%)
Query: 3 AAAECDVVMAATEPELLDDQEAKREAE--------TFKEQGNAYYAKKDYNEAYNYYTKA 54
A A C A E LD + A+ + E +++ + K+D+ + +A
Sbjct: 56 AMAACRSFQRALE---LDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRA 112
Query: 55 IDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMA 114
++ P + +A L MLGR+ EA A +R+D + G C
Sbjct: 113 LEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEK 172
Query: 115 ACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAP- 173
A + F +AL + + +A +NA A+ ++ F++ +++ AL P
Sbjct: 173 AVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPN 232
Query: 174 ---ACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAV 230
+ + + L + +A ++ +++D T A R C + E+AV
Sbjct: 233 NIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAV 292
Query: 231 QFFVQALRMAPDHE-KACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPN 288
+ + + + E K + + K+K++D Y + LG+D N
Sbjct: 293 RDYEKVYQTEKTKEHKQLLKNAQLELKKSKRKD----------------YYKILGVDKN 335
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 180 bits (457), Expect = 2e-45
Identities = 129/473 (27%), Positives = 220/473 (46%), Gaps = 11/473 (2%)
Query: 27 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ 86
+ E E G A +A + + A+D P N Y RA + +G+ + AL D
Sbjct: 36 DVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLT 95
Query: 87 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALEL---DHKNAQAQQEFKNANAVM 143
+ ++L F L+ G L G A F++ L+ +++ +AQ + ++ +
Sbjct: 96 KVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQ 155
Query: 144 EYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDIL 203
A F D+ + +D+ LE + L+AEC G +A S
Sbjct: 156 RLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAAS 215
Query: 204 RMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDG 263
++ + N +A Y Y E ++ + L++ DH++ + K L E
Sbjct: 216 KLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESA 275
Query: 264 NKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKL 323
+ ++G Y A Y + +P+ + + SK K +AI C+ +++
Sbjct: 276 EELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQM 335
Query: 324 DDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ-TEKTKEHKQLLKNAQLELRKSKRKDY 382
+ + A RA+ Y+ E Y+EA++DYE + E ++ ++ L+ AQ L++S+++DY
Sbjct: 336 EPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDY 395
Query: 383 YKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPK 442
YKILGV +NA + EI KAYRK AL HPD + E +K+ EKKF ++ A +LSDP+
Sbjct: 396 YKILGVKRNAKKQEIIKAYRKLALQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEVLSDPE 453
Query: 443 KKTRYDSGQD-LDEEGMNMGDFDPNNIFKAFFGGPGGFS-FEASGPGNFFFQF 493
+ ++D G+D LD E G +P F + GF+ F + GP F F F
Sbjct: 454 MRKKFDDGEDPLDAESQQGGGGNP---FHRSWNSWQGFNPFSSGGPFRFKFHF 503
>gi|201862587 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 1
[Homo sapiens]
Length = 420
Score = 91.7 bits (226), Expect = 1e-18
Identities = 52/115 (45%), Positives = 66/115 (57%), Gaps = 24/115 (20%)
Query: 380 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 439
KDYYKILG+ A+EDEIKKAYRK AL +HPD++ +A E+KFKE+ EA+ +LS
Sbjct: 75 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNA------EEKFKEIAEAYDVLS 128
Query: 440 DPKKKTRYDSGQDLDEEGMNMG---------------DFDPNNIFKAFFGGPGGF 479
DPKK+ YD EEG+ G DP+ F +FFGG F
Sbjct: 129 DPKKRGLYD---QYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPF 180
>gi|201862518 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 2
[Homo sapiens]
Length = 382
Score = 91.7 bits (226), Expect = 1e-18
Identities = 52/115 (45%), Positives = 66/115 (57%), Gaps = 24/115 (20%)
Query: 380 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 439
KDYYKILG+ A+EDEIKKAYRK AL +HPD++ +A E+KFKE+ EA+ +LS
Sbjct: 37 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNA------EEKFKEIAEAYDVLS 90
Query: 440 DPKKKTRYDSGQDLDEEGMNMG---------------DFDPNNIFKAFFGGPGGF 479
DPKK+ YD EEG+ G DP+ F +FFGG F
Sbjct: 91 DPKKRGLYD---QYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPF 142
>gi|56549115 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 3
[Homo sapiens]
Length = 348
Score = 91.7 bits (226), Expect = 1e-18
Identities = 52/115 (45%), Positives = 66/115 (57%), Gaps = 24/115 (20%)
Query: 380 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 439
KDYYKILG+ A+EDEIKKAYRK AL +HPD++ +A E+KFKE+ EA+ +LS
Sbjct: 3 KDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNA------EEKFKEIAEAYDVLS 56
Query: 440 DPKKKTRYDSGQDLDEEGMNMG---------------DFDPNNIFKAFFGGPGGF 479
DPKK+ YD EEG+ G DP+ F +FFGG F
Sbjct: 57 DPKKRGLYD---QYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPF 108
>gi|6631085 DnaJ (Hsp40) homolog, subfamily B, member 4 [Homo
sapiens]
Length = 337
Score = 90.1 bits (222), Expect = 4e-18
Identities = 52/115 (45%), Positives = 66/115 (57%), Gaps = 24/115 (20%)
Query: 380 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 439
KDYY ILG++K AS+++IKKAYRK+AL HPD++ AE +KFKEV EA+ +LS
Sbjct: 3 KDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAE------EKFKEVAEAYEVLS 56
Query: 440 DPKKKTRYDSGQDLDEEGMNMG---------------DFDPNNIFKAFFGGPGGF 479
DPKK+ YD EEG+ G DP+ F AFFGG F
Sbjct: 57 DPKKREIYD---QFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPF 108
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 89.0 bits (219), Expect = 9e-18
Identities = 42/136 (30%), Positives = 77/136 (56%), Gaps = 3/136 (2%)
Query: 24 AKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALG 83
A + AE K Q N Y+ KDY A +Y++AI++ P NA YYGNR+ + + ALG
Sbjct: 24 ALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALG 83
Query: 84 DAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVM 143
DA +++ LD +++G+ R +++LG AA R ++ +++ + A+ +++ N ++
Sbjct: 84 DATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIV 143
Query: 144 E---YEKIAETDFEKR 156
+ +E+ D KR
Sbjct: 144 KQKAFERAIAGDEHKR 159
Score = 63.2 bits (152), Expect = 5e-10
Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 11/151 (7%)
Query: 242 DHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRG 301
D A A + A+ LK + D FK +Y+ A + Y++A+ ++P+N A Y NR
Sbjct: 17 DEPPADGALKRAEELKTQAND---YFKAKDYENAIKFYSQAIELNPSN----AIYYGNRS 69
Query: 302 TVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTK 361
+ A+ D T A++LD YIK Y RRA M ++ A+RDYE V K K
Sbjct: 70 LAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVV---KVK 126
Query: 362 EHKQLLKNAQLELRK-SKRKDYYKILGVDKN 391
H + K E K K+K + + + D++
Sbjct: 127 PHDKDAKMKYQECNKIVKQKAFERAIAGDEH 157
>gi|17388799 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform a
[Homo sapiens]
Length = 326
Score = 89.0 bits (219), Expect = 9e-18
Identities = 51/118 (43%), Positives = 73/118 (61%), Gaps = 23/118 (19%)
Query: 381 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 440
DYY++LGV ++AS ++IKKAYRK AL HPD+ + E ++E E+KFK+V EA+ +LSD
Sbjct: 3 DYYEVLGVQRHASPEDIKKAYRKLALKWHPDK----NPENKEEAERKFKQVAEAYEVLSD 58
Query: 441 PKKKTRYDSGQDLDEEGMNMG-----DFD-----------PNNIFKAFFGGPGGFSFE 482
KK+ YD +EG+N G FD P+++F+ FFGG FSF+
Sbjct: 59 AKKRDIYDK---YGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFD 113
>gi|4885495 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b
[Homo sapiens]
Length = 241
Score = 89.0 bits (219), Expect = 9e-18
Identities = 51/118 (43%), Positives = 73/118 (61%), Gaps = 23/118 (19%)
Query: 381 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 440
DYY++LGV ++AS ++IKKAYRK AL HPD+ + E ++E E+KFK+V EA+ +LSD
Sbjct: 3 DYYEVLGVQRHASPEDIKKAYRKLALKWHPDK----NPENKEEAERKFKQVAEAYEVLSD 58
Query: 441 PKKKTRYDSGQDLDEEGMNMG-----DFD-----------PNNIFKAFFGGPGGFSFE 482
KK+ YD +EG+N G FD P+++F+ FFGG FSF+
Sbjct: 59 AKKRDIYDK---YGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFD 113
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 87.4 bits (215), Expect = 3e-17
Identities = 89/361 (24%), Positives = 138/361 (38%), Gaps = 89/361 (24%)
Query: 26 REAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDA 85
++A KE+GN Y+ + Y+EA + YTK +D P N NRA+ L +F A
Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVA---- 186
Query: 86 QQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEY 145
E C+L A+A RS+ +A A Q+ + A +Y
Sbjct: 187 ----------------ESDCNL----AVALNRSYTKAYSRRGAARFALQKLEEAKK--DY 224
Query: 146 EKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRM 205
E++ E E +F A + + + + YP+ +
Sbjct: 225 ERVLE--LEPNNFE--------------ATNELRKISQALASKENSYPKEADIV------ 262
Query: 206 DSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNK 265
++ K A +N + ++K+ GN
Sbjct: 263 -------------------------------IKSTEGERKQIEAQQNKQQAISEKDRGNG 291
Query: 266 AFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDD 325
FKEG Y+ A E YT + D NA L NR K++K ++A +DCT A+ LD
Sbjct: 292 FFKEGKYERAIECYTRGIAADG----ANALLPANRAMAYLKIQKYEEAEKDCTQAILLDG 347
Query: 326 TYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRKDYYKI 385
+Y KA+ RR + EA +D+E V E K A EL K K+K K+
Sbjct: 348 SYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN------KQAVTELSKIKKKPLKKV 401
Query: 386 L 386
+
Sbjct: 402 I 402
Score = 75.9 bits (185), Expect = 8e-14
Identities = 64/198 (32%), Positives = 91/198 (45%), Gaps = 20/198 (10%)
Query: 235 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 294
++L + E+ I + KAL KE GNK FK+G Y A + YT+ + DP N
Sbjct: 113 ESLSQESESEEDGIHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN----P 167
Query: 295 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 354
L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE+V
Sbjct: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
Query: 355 YQTEKTKEHKQLLKNAQLELRK------SKRKDYYKILGVDKNASEDE---IKKAYRKRA 405
+ E A ELRK SK Y K + ++E E I+ K+
Sbjct: 228 LELEPNN------FEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQ 281
Query: 406 LMHHPDRHSGASAEVQKE 423
+ DR +G E + E
Sbjct: 282 AISEKDRGNGFFKEGKYE 299
Score = 68.2 bits (165), Expect = 2e-11
Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 6 ECDVVMAATEPEL--LDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNAS 63
E D+V+ +TE E ++ Q+ K++A + K++GN ++ + Y A YT+ I NA
Sbjct: 258 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 317
Query: 64 YYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRAL 123
NRA + + ++ EA D Q++ LD S+ + R G LG A + F+ L
Sbjct: 318 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 377
Query: 124 ELDHKNAQAQQE 135
L+ N QA E
Sbjct: 378 LLEPGNKQAVTE 389
>gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo
sapiens]
Length = 397
Score = 87.0 bits (214), Expect = 3e-17
Identities = 47/110 (42%), Positives = 64/110 (58%), Gaps = 10/110 (9%)
Query: 378 KRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTI 437
K YY +LGV NA+++E+KKAYRK AL +HPD++ E +KFK++ +A+ +
Sbjct: 3 KETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKN--------PNEGEKFKQISQAYEV 54
Query: 438 LSDPKKKTRYDSG--QDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASG 485
LSD KK+ YD G Q + E G G P +IF FFGG G E G
Sbjct: 55 LSDAKKRELYDKGGEQAIKEGGAGGGFGSPMDIFDMFFGGGGRMQRERRG 104
>gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 1
[Homo sapiens]
Length = 426
Score = 87.0 bits (214), Expect = 3e-17
Identities = 55/148 (37%), Positives = 76/148 (51%), Gaps = 22/148 (14%)
Query: 341 TEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDEIKKA 400
++ + D + QT + HK + K YY ILGV +AS +EIKKA
Sbjct: 6 SQSWSSGESDGQPKEQTPEKPRHKMV-----------KETQYYDILGVKPSASPEEIKKA 54
Query: 401 YRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSG--QDLDEEGM 458
YRK AL +HPD++ +E +KFK + +A+ +LSDPKK+ YD G Q + E G
Sbjct: 55 YRKLALKYHPDKN--------PDEGEKFKLISQAYEVLSDPKKRDVYDQGGEQAIKEGGS 106
Query: 459 NMGDF-DPNNIFKAFFGGPGGFSFEASG 485
F P +IF FFGG G + E G
Sbjct: 107 GSPSFSSPMDIFDMFFGGGGRMARERRG 134
>gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 2
[Homo sapiens]
Length = 397
Score = 86.3 bits (212), Expect = 6e-17
Identities = 50/111 (45%), Positives = 65/111 (58%), Gaps = 11/111 (9%)
Query: 378 KRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTI 437
K YY ILGV +AS +EIKKAYRK AL +HPD++ +E +KFK + +A+ +
Sbjct: 3 KETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKN--------PDEGEKFKLISQAYEV 54
Query: 438 LSDPKKKTRYDSG--QDLDEEGMNMGDF-DPNNIFKAFFGGPGGFSFEASG 485
LSDPKK+ YD G Q + E G F P +IF FFGG G + E G
Sbjct: 55 LSDPKKRDVYDQGGEQAIKEGGSGSPSFSSPMDIFDMFFGGGGRMARERRG 105
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 86.3 bits (212), Expect = 6e-17
Identities = 47/118 (39%), Positives = 65/118 (55%), Gaps = 5/118 (4%)
Query: 260 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 319
K++GN KE NY A + YT+A+ +DPNN A YCNR SKL DAI+DC
Sbjct: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNN----AVYYCNRAAAQSKLGHYTDAIKDCEK 144
Query: 320 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE-KTKEHKQLLKNAQLELRK 376
A+ +D Y KAY R ++EEAV Y+K + + +K LK A+ +LR+
Sbjct: 145 AIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
Score = 75.1 bits (183), Expect = 1e-13
Identities = 37/113 (32%), Positives = 66/113 (58%)
Query: 27 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ 86
+A+ K++GN + +++Y A + YT+AI++ P NA YY NRAA LG + +A+ D +
Sbjct: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCE 143
Query: 87 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNA 139
+++ +D + + + R G +L A S+Q+AL+LD +N + K A
Sbjct: 144 KAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIA 196
Score = 33.1 bits (74), Expect = 0.59
Identities = 22/91 (24%), Positives = 43/91 (47%)
Query: 154 EKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADAL 213
++ ++ V C +A+E P + +A + LG Y +A + +DS + A
Sbjct: 97 KEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAY 156
Query: 214 YVRGLCLYYEDCIEKAVQFFVQALRMAPDHE 244
GL L + E+AV + +AL + P+++
Sbjct: 157 GRMGLALTALNKFEEAVTSYQKALDLDPEND 187
>gi|47777312 DnaJ (Hsp40) homolog, subfamily B, member 3 [Homo
sapiens]
Length = 145
Score = 84.3 bits (207), Expect = 2e-16
Identities = 48/118 (40%), Positives = 67/118 (56%), Gaps = 17/118 (14%)
Query: 381 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 440
DYY++L V + AS + IKKAYRK AL HPD+ + E ++E E++FK+V EA+ +LSD
Sbjct: 3 DYYEVLDVPRQASSEAIKKAYRKLALKWHPDK----NPENKEEAERRFKQVAEAYEVLSD 58
Query: 441 PKKKTRYDSGQDLDEEGMNMGD-------------FDPNNIFKAFFGGPGGFSFEASG 485
KK+ YD + EG G DP ++F+ FFGG FSF+ G
Sbjct: 59 AKKRDIYDRYGEAGAEGGCTGGRPFEDPFEYVFSFRDPADVFREFFGGQDPFSFDLLG 116
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 83.6 bits (205), Expect = 4e-16
Identities = 87/355 (24%), Positives = 135/355 (38%), Gaps = 89/355 (25%)
Query: 26 REAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDA 85
++A KE+GN Y+ + Y+EA + YTK +D P N NRA+ L +F A
Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVA---- 186
Query: 86 QQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEY 145
E C+L A+A RS+ +A A Q+ + A +Y
Sbjct: 187 ----------------ESDCNL----AVALNRSYTKAYSRRGAARFALQKLEEAKK--DY 224
Query: 146 EKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRM 205
E++ E E +F A + + + + YP+ +
Sbjct: 225 ERVLE--LEPNNFE--------------ATNELRKISQALASKENSYPKEADIV------ 262
Query: 206 DSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNK 265
++ K A +N + ++K+ GN
Sbjct: 263 -------------------------------IKSTEGERKQIEAQQNKQQAISEKDRGNG 291
Query: 266 AFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDD 325
FKEG Y+ A E YT + D NA L NR K++K ++A +DCT A+ LD
Sbjct: 292 FFKEGKYERAIECYTRGIAADG----ANALLPANRAMAYLKIQKYEEAEKDCTQAILLDG 347
Query: 326 TYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRK 380
+Y KA+ RR + EA +D+E V E K A EL K K++
Sbjct: 348 SYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN------KQAVTELSKIKKE 396
Score = 75.9 bits (185), Expect = 8e-14
Identities = 64/198 (32%), Positives = 91/198 (45%), Gaps = 20/198 (10%)
Query: 235 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 294
++L + E+ I + KAL KE GNK FK+G Y A + YT+ + DP N
Sbjct: 113 ESLSQESESEEDGIHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN----P 167
Query: 295 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 354
L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE+V
Sbjct: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
Query: 355 YQTEKTKEHKQLLKNAQLELRK------SKRKDYYKILGVDKNASEDE---IKKAYRKRA 405
+ E A ELRK SK Y K + ++E E I+ K+
Sbjct: 228 LELEPNN------FEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQ 281
Query: 406 LMHHPDRHSGASAEVQKE 423
+ DR +G E + E
Sbjct: 282 AISEKDRGNGFFKEGKYE 299
Score = 68.2 bits (165), Expect = 2e-11
Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Query: 6 ECDVVMAATEPEL--LDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNAS 63
E D+V+ +TE E ++ Q+ K++A + K++GN ++ + Y A YT+ I NA
Sbjct: 258 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 317
Query: 64 YYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRAL 123
NRA + + ++ EA D Q++ LD S+ + R G LG A + F+ L
Sbjct: 318 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 377
Query: 124 ELDHKNAQAQQE 135
L+ N QA E
Sbjct: 378 LLEPGNKQAVTE 389
>gi|23503241 DnaJ homolog, subfamily B, member 8 [Homo sapiens]
Length = 232
Score = 82.0 bits (201), Expect = 1e-15
Identities = 51/115 (44%), Positives = 69/115 (60%), Gaps = 17/115 (14%)
Query: 381 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 440
+YY++LGV +AS ++IKKAYRK AL HPD+ + + ++E EKKFK V EA+ +LSD
Sbjct: 3 NYYEVLGVQASASPEDIKKAYRKLALRWHPDK----NPDNKEEAEKKFKLVSEAYEVLSD 58
Query: 441 PKKKTRYD-SGQDLDEEGMNM-----GDFD-------PNNIFKAFFGGPGGFSFE 482
KK++ YD +G D G FD P +IF+ FFGG FSFE
Sbjct: 59 SKKRSLYDRAGCDSWRAGGGASTPYHSPFDTGYTFRNPEDIFREFFGGLDPFSFE 113
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 79.3 bits (194), Expect = 7e-15
Identities = 59/245 (24%), Positives = 110/245 (44%), Gaps = 25/245 (10%)
Query: 137 KNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQ 196
+N ++ +++ ++K+DF + D+A E P + +A G Y + +
Sbjct: 220 ENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCR 279
Query: 197 SVASDILRMDSTNAD------ALYVR-GLCLYYEDCIEKAVQFFVQAL--RMAPDHEKAC 247
+ + + N + Y R G + E+ + A+ F+ ++L PD K C
Sbjct: 280 ELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKC 339
Query: 248 ------------IACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAK 295
+A N +K GN+ F++G+Y A + YTEA+ +P + AK
Sbjct: 340 QQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKD----AK 395
Query: 296 LYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVY 355
LY NR +KL + A++DC ++L+ T+IK Y R+A + Y +A+ Y+K
Sbjct: 396 LYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKAL 455
Query: 356 QTEKT 360
+ +
Sbjct: 456 DLDSS 460
Score = 78.2 bits (191), Expect = 2e-14
Identities = 89/395 (22%), Positives = 164/395 (41%), Gaps = 22/395 (5%)
Query: 27 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ 86
+ KE+GN + + ++A Y++AI + P N Y NR+A G +++A D
Sbjct: 3 QVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGC 62
Query: 87 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYE 146
++V L + +G+ R+ L A R+++ L+ + N Q ++ +N A
Sbjct: 63 KTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEA----- 117
Query: 147 KIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKA-----ECLAMLGRYPEAQSVASD 201
++AE F F M + + R + L + E + L P
Sbjct: 118 RLAERKFMN------PFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQ 171
Query: 202 ILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKE 261
R+ +T + L V + E+ I P+ + + +ALK +KE
Sbjct: 172 DPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALK-EKE 230
Query: 262 DGNKAFKEGNYKLAYELYTEALGIDPNN---IKTNAKLYCNRGTVNSKLRKLDDAIEDCT 318
GN A+K+ ++ A + Y +A +DP N I A +Y +G N + AIE
Sbjct: 231 LGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGR 290
Query: 319 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSK 378
+ KAY R Y E+Y++A+ Y K +T + + + A+ L++ +
Sbjct: 291 ENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQE 350
Query: 379 RKDYYK--ILGVDKNASEDEIKKAYRKRALMHHPD 411
R Y + +KN + +K +A+ H+ +
Sbjct: 351 RLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTE 385
Score = 69.3 bits (168), Expect = 7e-12
Identities = 37/125 (29%), Positives = 66/125 (52%)
Query: 32 KEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRL 91
K +GN + K DY +A +YT+AI PK+A Y NRAA L F+ AL D ++ ++L
Sbjct: 364 KNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQL 423
Query: 92 DDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAET 151
+ +F++G+ R+ ++ + A +Q+AL+LD +A ++ +
Sbjct: 424 EPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPE 483
Query: 152 DFEKR 156
D ++R
Sbjct: 484 DVKRR 488
Score = 61.2 bits (147), Expect = 2e-09
Identities = 64/275 (23%), Positives = 116/275 (42%), Gaps = 27/275 (9%)
Query: 14 TEPELLDDQ--EAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAAT 71
T+PE +++ E K++A KE GN Y KKD++ A +Y KA ++ P N +Y N+AA
Sbjct: 209 TKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAV 268
Query: 72 LMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQ 131
G + + ++++ + + + K + +GN+ ++ A+ +K+
Sbjct: 269 YFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLA 328
Query: 132 AQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGR 191
+ + EKI K R D ALE K EC G
Sbjct: 329 EHRTPDVLKKCQQAEKIL-----KEQERLAYINPDLALE-------EKNKGNECF-QKGD 375
Query: 192 YPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACR 251
YP+A ++ ++ + +A R C + A++ + +++ P K R
Sbjct: 376 YPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKG--YTR 433
Query: 252 NAKALKAKKEDGNKAFKEGNYKLAYELYTEALGID 286
A AL+A K+ Y A ++Y +AL +D
Sbjct: 434 KAAALEAMKD----------YTKAMDVYQKALDLD 458
Score = 60.8 bits (146), Expect = 3e-09
Identities = 54/187 (28%), Positives = 83/187 (44%), Gaps = 18/187 (9%)
Query: 260 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 319
KE GNKA GN A + Y+EA+ +DP+N LY NR +K A ED
Sbjct: 8 KEKGNKALSVGNIDDALQCYSEAIKLDPHN----HVLYSNRSAAYAKKGDYQKAYEDGCK 63
Query: 320 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE-KTKEHKQLLKNAQLELRKSK 378
V L + K Y R+A ++EEA R YE+ + E + K+ L+N + L + K
Sbjct: 64 TVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERK 123
Query: 379 RKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTIL 438
+ + + + + D R R L+ P E+ ++ K ++G T L
Sbjct: 124 FMNPFNMPNLYQKLESDP-----RTRTLLSDP-----TYRELIEQLRNKPSDLG---TKL 170
Query: 439 SDPKKKT 445
DP+ T
Sbjct: 171 QDPRIMT 177
>gi|194306642 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo
sapiens]
Length = 409
Score = 79.3 bits (194), Expect = 7e-15
Identities = 44/113 (38%), Positives = 65/113 (57%), Gaps = 18/113 (15%)
Query: 375 RKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEA 434
R + KDYY+ILGV + AS++++KKAYR+ AL HPD++ A + FK +G A
Sbjct: 138 RVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGA------TEAFKAIGTA 191
Query: 435 FTILSDPKKKTRYDS-GQDLDE---EGMNMGDF--------DPNNIFKAFFGG 475
+ +LS+P+K+ +YD G D + G GDF P ++F FFGG
Sbjct: 192 YAVLSNPEKRKQYDQFGDDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGG 244
>gi|194306640 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo
sapiens]
Length = 409
Score = 79.3 bits (194), Expect = 7e-15
Identities = 44/113 (38%), Positives = 65/113 (57%), Gaps = 18/113 (15%)
Query: 375 RKSKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEA 434
R + KDYY+ILGV + AS++++KKAYR+ AL HPD++ A + FK +G A
Sbjct: 138 RVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGA------TEAFKAIGTA 191
Query: 435 FTILSDPKKKTRYDS-GQDLDE---EGMNMGDF--------DPNNIFKAFFGG 475
+ +LS+P+K+ +YD G D + G GDF P ++F FFGG
Sbjct: 192 YAVLSNPEKRKQYDQFGDDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGG 244
>gi|5453690 DnaJ (Hsp40) homolog, subfamily B, member 1 [Homo
sapiens]
Length = 340
Score = 77.4 bits (189), Expect = 3e-14
Identities = 44/116 (37%), Positives = 66/116 (56%), Gaps = 22/116 (18%)
Query: 380 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 439
KDYY+ LG+ + AS++EIK+AYR++AL +HPD++ A E+KFKE+ EA+ +LS
Sbjct: 3 KDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGA------EEKFKEIAEAYDVLS 56
Query: 440 DPKKKTRYD--SGQDLDEEGMNMGD--------------FDPNNIFKAFFGGPGGF 479
DP+K+ +D + L G + G DP+ +F FFGG F
Sbjct: 57 DPRKREIFDRYGEEGLKGSGPSGGSGGGANGTSFSYTFHGDPHAMFAEFFGGRNPF 112
>gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo
sapiens]
Length = 358
Score = 75.9 bits (185), Expect = 8e-14
Identities = 49/154 (31%), Positives = 79/154 (51%), Gaps = 30/154 (19%)
Query: 339 MDTEQYEEAVRDYEKVYQTE--KTKEHKQLLKNAQLELRKSKRKDYYKILGVDKNASEDE 396
M ++ +++ ++ + Q E T +QLL +++ K ++YY+ILGV ++AS++E
Sbjct: 42 MKAQKEKKSENEWTQTRQGEGNSTYSEEQLLGVQRIK----KCRNYYEILGVSRDASDEE 97
Query: 397 IKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQDLDEE 456
+KKAYRK AL HPD++ A FK +G AF +LS+P K+ RYD + +E
Sbjct: 98 LKKAYRKLALKFHPDKNCAPGA------TDAFKAIGNAFAVLSNPDKRLRYD---EYGDE 148
Query: 457 GMNM---------------GDFDPNNIFKAFFGG 475
+ D P +F FFGG
Sbjct: 149 QVTFTAPRARPYNYYRDFEADITPEELFNVFFGG 182
>gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform a
[Homo sapiens]
Length = 277
Score = 75.5 bits (184), Expect = 1e-13
Identities = 47/112 (41%), Positives = 66/112 (58%), Gaps = 9/112 (8%)
Query: 382 YYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDP 441
YY+IL V ++AS D+IKKAYR++AL HPD+ + + ++ EKKFKEV EA+ +LSD
Sbjct: 4 YYEILDVPRSASADDIKKAYRRKALQWHPDK----NPDNKEFAEKKFKEVAEAYEVLSDK 59
Query: 442 KKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQF 493
K+ YD EG+ P+ +A GGP GF+F P F +F
Sbjct: 60 HKREIYDR---YGREGLTGTGTGPSRA-EAGSGGP-GFTFTFRSPEEVFREF 106
>gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform b
[Homo sapiens]
Length = 324
Score = 75.5 bits (184), Expect = 1e-13
Identities = 47/112 (41%), Positives = 66/112 (58%), Gaps = 9/112 (8%)
Query: 382 YYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDP 441
YY+IL V ++AS D+IKKAYR++AL HPD+ + + ++ EKKFKEV EA+ +LSD
Sbjct: 4 YYEILDVPRSASADDIKKAYRRKALQWHPDK----NPDNKEFAEKKFKEVAEAYEVLSDK 59
Query: 442 KKKTRYDSGQDLDEEGMNMGDFDPNNIFKAFFGGPGGFSFEASGPGNFFFQF 493
K+ YD EG+ P+ +A GGP GF+F P F +F
Sbjct: 60 HKREIYDR---YGREGLTGTGTGPSRA-EAGSGGP-GFTFTFRSPEEVFREF 106
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 75.5 bits (184), Expect = 1e-13
Identities = 38/100 (38%), Positives = 63/100 (63%), Gaps = 1/100 (1%)
Query: 260 KEDGNKAFKEGNYKLAYELYTEALGIDPNNI-KTNAKLYCNRGTVNSKLRKLDDAIEDCT 318
KE+GN+ FK+G+Y A Y+ AL + P+ K + L+ NR K K + AI DC+
Sbjct: 120 KEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCS 179
Query: 319 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE 358
A++L+ +YI+A LRRA+ Y T++ +EA+ DY+ + + +
Sbjct: 180 KAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKD 219
Score = 65.1 bits (157), Expect = 1e-10
Identities = 37/127 (29%), Positives = 67/127 (52%), Gaps = 7/127 (5%)
Query: 15 EPELLDDQEAKREAET--FKEQGNAYYAKKDYNEAYNYYTKAIDMCP-----KNASYYGN 67
E + D+++ KR E+ KE+GN + K DY EA + Y++A++MCP + + + N
Sbjct: 101 EKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSN 160
Query: 68 RAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDH 127
RAA M + A+ D ++++L+ S++R LR + + A ++ LE D
Sbjct: 161 RAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDP 220
Query: 128 KNAQAQQ 134
QA++
Sbjct: 221 SIHQARE 227
Score = 31.2 bits (69), Expect = 2.3
Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 16/179 (8%)
Query: 123 LELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFK--I 180
+EL+ KN +++ K ++ F+K D+ + RALE P+C + + I
Sbjct: 98 IELE-KNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSI 156
Query: 181 LKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYE-----DCIEKAVQFFVQ 235
L + A + + + +D + N Y+R + E D +++A++ +
Sbjct: 157 LFSNRAAARMKQDKKEMAINDCSKAIQLNPS--YIRAILRRAELYEKTDKLDEALEDYKS 214
Query: 236 ALRMAPDHEKACIACRNAKALKAKKEDGNKAFKE---GNYKLAYELYTEALGIDPNNIK 291
L P +A AC L + E+ N+ KE G K L G+ N +
Sbjct: 215 ILEKDPSIHQAREACMR---LPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQ 270
>gi|72534740 DnaJ (Hsp40) homolog, subfamily B, member 14 isoform 1
[Homo sapiens]
Length = 379
Score = 74.7 bits (182), Expect = 2e-13
Identities = 40/112 (35%), Positives = 64/112 (57%), Gaps = 20/112 (17%)
Query: 377 SKRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFT 436
+K K+YY++LGV K+A ++++KKAYRK AL HPD++ A FK++G A+
Sbjct: 104 NKCKNYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGA------TDAFKKIGNAYA 157
Query: 437 ILSDPKKKTRYDSGQDLDEEGMN-------------MGDFDPNNIFKAFFGG 475
+LS+P+K+ +YD + +E+ N D P ++F FFGG
Sbjct: 158 VLSNPEKRKQYDLTGN-EEQACNHQNNGRFNFHRGCEADITPEDLFNIFFGG 208
>gi|21553335 DnaJ (Hsp40) homolog, subfamily B, member 7 [Homo
sapiens]
Length = 309
Score = 74.3 bits (181), Expect = 2e-13
Identities = 46/114 (40%), Positives = 66/114 (57%), Gaps = 20/114 (17%)
Query: 381 DYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSD 440
DYY++LG+ + AS ++IKKAY K AL HPD+ + E ++E E+KFKEV EA+ +LS+
Sbjct: 3 DYYEVLGLQRYASPEDIKKAYHKVALKWHPDK----NPENKEEAERKFKEVAEAYEVLSN 58
Query: 441 PKKKTRYDSGQDLDEEGMNMG--DFD-----------PNNIFKAFFGGPGGFSF 481
+K+ YD EG+N G FD P+++FK F FSF
Sbjct: 59 DEKRDIYDK---YGTEGLNGGGSHFDDECEYGFTFHKPDDVFKEIFHERDPFSF 109
>gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precursor
[Homo sapiens]
Length = 358
Score = 73.9 bits (180), Expect = 3e-13
Identities = 42/99 (42%), Positives = 62/99 (62%), Gaps = 9/99 (9%)
Query: 380 KDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTILS 439
+D+YKILGV ++AS +IKKAYRK AL HPDR+ + ++KF+++G A+ +LS
Sbjct: 24 RDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPD-----DPQAQEKFQDLGAAYEVLS 78
Query: 440 DPKKKTRYDSGQDLDEEGMNMG-DFDPNNIFKAFFGGPG 477
D +K+ +YD+ EEG+ G +IF FFG G
Sbjct: 79 DSEKRKQYDT---YGEEGLKDGHQSSHGDIFSHFFGDFG 114
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 72.8 bits (177), Expect = 7e-13
Identities = 47/147 (31%), Positives = 73/147 (49%), Gaps = 3/147 (2%)
Query: 241 PDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTN-AKLYCN 299
P+ A + + +A K GNK FK G Y+ A + YTEA+ + P + + Y N
Sbjct: 99 PEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQN 158
Query: 300 RGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEK 359
R +L+K + +DCT AV+L+ Y+KA RRA+ + + +E + D V E
Sbjct: 159 RAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEG 218
Query: 360 -TKEHKQLLKNAQLE-LRKSKRKDYYK 384
+ LL + L+ L K K K+ YK
Sbjct: 219 FQNQQSMLLADKVLKLLGKEKAKEKYK 245
Score = 62.4 bits (150), Expect = 9e-10
Identities = 72/342 (21%), Positives = 132/342 (38%), Gaps = 31/342 (9%)
Query: 21 DQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCP--KN---ASYYGNRAATLMML 75
D + A+ K +GN Y+ Y +A YT+AI +CP KN +++Y NRAA L
Sbjct: 107 DMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQL 166
Query: 76 GRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQE 135
+++E D ++V L+ +V+ R K H L N L+ Q QQ
Sbjct: 167 QKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE--GFQNQQS 224
Query: 136 FKNANAVMEY--EKIAETDFEKRD--FRKVVFCMDRALEFAPACHRFKILKAECLAMLGR 191
A+ V++ ++ A+ ++ R+ F F +LK E +
Sbjct: 225 MLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGE------K 278
Query: 192 YPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACR 251
E + + L + + Y++ E+ +K + + + + + R
Sbjct: 279 SDEDKDKEGEALEVKENSG---YLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLR 335
Query: 252 NAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLD 311
L GN A + + + N+K A RG++ + ++
Sbjct: 336 ATFYLLI-----------GNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPL 384
Query: 312 DAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEK 353
+ +D A +D Y R Q + +Q EEAV D+++
Sbjct: 385 LSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDE 426
Score = 35.8 bits (81), Expect = 0.092
Identities = 52/246 (21%), Positives = 97/246 (39%), Gaps = 35/246 (14%)
Query: 13 ATEPEL-----LDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGN 67
A +P+L L + K A ++G+ Y ++ + + A D+ P+NA Y +
Sbjct: 347 AAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHH 406
Query: 68 RAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDH 127
R ++L + EA+ D + +RL + +L A C + R +
Sbjct: 407 RGQLKILLDQVEEAVADFDECIRL------------RPESALAQAQ-KCFALYRQAYTGN 453
Query: 128 KNAQAQQEFKNANAVME--------YEKIAETDFEKRDFRKVVFCMDRALEFAP-----A 174
++Q Q K V++ Y A+ +++ F K D+ ++ P
Sbjct: 454 NSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTY 513
Query: 175 CHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFV 234
H+ +L+ + L R E S A +I D+ A G +EKA+ F
Sbjct: 514 VHK-GLLQLQWKQDLDRGLELISKAIEI---DNKCDFAYETMGTIEVQRGNMEKAIDMFN 569
Query: 235 QALRMA 240
+A+ +A
Sbjct: 570 KAINLA 575
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,489,687
Number of Sequences: 37866
Number of extensions: 751594
Number of successful extensions: 3777
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 120
Number of HSP's that attempted gapping in prelim test: 2986
Number of HSP's gapped (non-prelim): 651
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.