Guide to the Human Genome
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Search of human proteins with 221136993

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
sapiens]
         (258 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa...   528   e-150
gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo sapi...   507   e-144
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ...    43   2e-04
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap...    43   2e-04
gi|38505222 thioredoxin domain containing 10 [Homo sapiens]            42   4e-04
gi|4758304 protein disulfide isomerase A4 [Homo sapiens]               42   7e-04
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s...    40   0.003
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s...    39   0.003
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul...    39   0.006
gi|151101292 thioredoxin domain containing 1 [Homo sapiens]            38   0.010
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]    37   0.017
gi|50592994 thioredoxin [Homo sapiens]                                 36   0.029
gi|94421469 disulfide isomerase [Homo sapiens]                         34   0.11 
gi|5031973 protein disulfide isomerase A6 [Homo sapiens]               34   0.14 
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap...    33   0.19 
gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo sap...    33   0.19 
gi|21361403 thioredoxin 2 precursor [Homo sapiens]                     33   0.25 
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa...    33   0.32 
gi|94966757 protein disulfide isomerase A2 [Homo sapiens]              32   0.55 
gi|28372543 protein disulfide isomerase-like, testis expressed [...    31   0.93 
gi|237648961 thioredoxin domain containing 16 isoform 2 [Homo sa...    31   1.2  
gi|237648959 thioredoxin domain containing 16 isoform 1 [Homo sa...    31   1.2  
gi|110349719 titin isoform N2-A [Homo sapiens]                         30   2.1  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      30   2.1  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      30   2.1  
gi|110349715 titin isoform N2-B [Homo sapiens]                         30   2.1  
gi|189217904 RPGRIP1-like isoform b [Homo sapiens]                     29   3.6  
gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]           28   6.1  
gi|134152674 rabaptin, RAB GTPase binding effector protein 1 iso...    28   6.1  
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof...    28   6.1  

>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
           sapiens]
          Length = 258

 Score =  528 bits (1359), Expect = e-150
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD 60
           MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
Sbjct: 1   MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD 60

Query: 61  FDWREVEILMFLSAIVMMKNRRSMFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTW 120
           FDWREVEILMFLSAIVMMKNRRSMFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTW
Sbjct: 61  FDWREVEILMFLSAIVMMKNRRSMFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTW 120

Query: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLP 180
           IVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLP
Sbjct: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLP 180

Query: 181 TLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQ 240
           TLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQ
Sbjct: 181 TLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQ 240

Query: 241 PVASTPTTVSDGENKKDK 258
           PVASTPTTVSDGENKKDK
Sbjct: 241 PVASTPTTVSDGENKKDK 258


>gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo
           sapiens]
          Length = 296

 Score =  507 bits (1306), Expect = e-144
 Identities = 257/296 (86%), Positives = 258/296 (87%), Gaps = 38/296 (12%)

Query: 1   MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD 60
           MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
Sbjct: 1   MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD 60

Query: 61  FDWREVEILMFLSAIVMMKNRRSM------------------------------------ 84
           FDWREVEILMFLSAIVMMKNRRS+                                    
Sbjct: 61  FDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLC 120

Query: 85  --FLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL 142
             FLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
Sbjct: 121 IVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL 180

Query: 143 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR 202
           SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
Sbjct: 181 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR 240

Query: 203 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK 258
           AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
Sbjct: 241 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK 296


>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
           [Homo sapiens]
          Length = 432

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 8/71 (11%)

Query: 122 VEFFANWSNDCQSFAPIYADLSLKY--NCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQL 179
           ++F+A W   C++ AP + +LS K      G+   +VD     ++ ++Y V      +  
Sbjct: 343 IKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSV------RGY 396

Query: 180 PTLILFQGGKE 190
           PTL+LF+GGK+
Sbjct: 397 PTLLLFRGGKK 407



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 3/72 (4%)

Query: 122 VEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPT 181
           V FFA W   CQ   P + DL  KYN   +   KV V +  D +    V ++   +  PT
Sbjct: 82  VMFFAPWCGHCQRLQPTWNDLGDKYN--SMEDAKVYVAK-VDCTAHSDVCSAQGVRGYPT 138

Query: 182 LILFQGGKEAMR 193
           L LF+ G+EA++
Sbjct: 139 LKLFKPGQEAVK 150



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 7/70 (10%)

Query: 122 VEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGK-VDVGRYTDVSTRYKVSTSPLTKQLP 180
           ++FFA W   C++ AP +  L+L     GL   + V +G+  D +  Y++ +    +  P
Sbjct: 210 IKFFAPWCGHCKALAPTWEQLAL-----GLEHSETVKIGK-VDCTQHYELCSGNQVRGYP 263

Query: 181 TLILFQGGKE 190
           TL+ F+ GK+
Sbjct: 264 TLLWFRDGKK 273


>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
           sapiens]
          Length = 324

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 22/71 (30%), Positives = 39/71 (54%), Gaps = 8/71 (11%)

Query: 122 VEFFANWSNDCQSFAPIYADLSLKY--NCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQL 179
           ++F+A W   C++ AP + +LS K      G+   +VD     ++ ++Y V      +  
Sbjct: 235 IKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSV------RGY 288

Query: 180 PTLILFQGGKE 190
           PTL+LF+GGK+
Sbjct: 289 PTLLLFRGGKK 299



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 7/70 (10%)

Query: 122 VEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGK-VDVGRYTDVSTRYKVSTSPLTKQLP 180
           ++FFA W   C++ AP +  L+L     GL   + V +G+  D +  Y++ +    +  P
Sbjct: 102 IKFFAPWCGHCKALAPTWEQLAL-----GLEHSETVKIGK-VDCTQHYELCSGNQVRGYP 155

Query: 181 TLILFQGGKE 190
           TL+ F+ GK+
Sbjct: 156 TLLWFRDGKK 165


>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
          Length = 454

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 108 IDEELERDKRVT-WIVEFFANWSNDCQSFAPIYADLSLKYNCTG--LNFGKVDVGRYTDV 164
           +DE  + ++    W+V+F+A W   C+   PI+ ++ L+    G  +  GK+D   Y+ +
Sbjct: 31  LDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSI 90

Query: 165 STRYKVSTSPLTKQL 179
           ++ + V   P  K L
Sbjct: 91  ASEFGVRGYPTIKLL 105


>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
          Length = 645

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 7/95 (7%)

Query: 100 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 158
           +K    KT D  +  D +   ++EF+A W   C+   P+Y  L+ KY    GL   K+D 
Sbjct: 527 VKVVVGKTFDS-IVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDA 585

Query: 159 GRYTDVSTRYKVSTSPLTKQLPT-----LILFQGG 188
                 S RYKV   P     P+      + F+GG
Sbjct: 586 TANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGG 620



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 8/71 (11%)

Query: 121 IVEFFANWSNDCQSFAPIY--ADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQ 178
           +VEF+A W   C+  AP Y  A   L      +   KVD    TD++ R+ VS       
Sbjct: 198 LVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVS------G 251

Query: 179 LPTLILFQGGK 189
            PTL +F+ G+
Sbjct: 252 YPTLKIFRKGR 262



 Score = 35.8 bits (81), Expect = 0.038
 Identities = 33/141 (23%), Positives = 56/141 (39%), Gaps = 28/141 (19%)

Query: 119 TWIVEFFANWSNDCQSFAPIYADLS--LKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLT 176
           T ++EF+A W   C+ FAP Y  ++  LK     +   K+D    + +++R+ VS  P  
Sbjct: 81  TVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTI 140

Query: 177 KQLPTLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNI 236
           K L                   KKG+AV +  S           E+  + +++S+     
Sbjct: 141 KIL-------------------KKGQAVDYEGSRTQ-------EEIVAKVREVSQPDWTP 174

Query: 237 PEEQPVASTPTTVSDGENKKD 257
           P E  +  T     +  N  D
Sbjct: 175 PPEVTLVLTKENFDEVVNDAD 195


>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
           sapiens]
          Length = 508

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 8/73 (10%)

Query: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTG--LNFGKVDVGRYTDVSTRYKVSTSPLTKQ 178
           +VEF+A W   C++ AP YA  + K    G  +   KVD    +D++ +Y V      + 
Sbjct: 45  LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGV------RG 98

Query: 179 LPTLILFQGGKEA 191
            PT+  F+ G  A
Sbjct: 99  YPTIKFFRNGDTA 111



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 13/37 (35%), Positives = 20/37 (54%)

Query: 110 EELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY 146
           E++  D++    VEF+A W   C+  API+  L   Y
Sbjct: 378 EDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETY 414


>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
           sapiens]
          Length = 793

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 7/116 (6%)

Query: 97  PEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKV 156
           P+       +T  E++ + K   W+++F+A W   CQ+FAP + +L  +     +  GKV
Sbjct: 669 PQVSTDLTPQTFSEKVLQGKN-HWVIDFYAPWCGPCQNFAPEF-ELLARMIKGKVKAGKV 726

Query: 157 DVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQID-KKGRAVSWTFSEE 211
           D   Y     +  +   P  K       ++  K   +  QI+ +  +A++   SE+
Sbjct: 727 DCQAYAQTCQKAGIRAYPTVK----FYFYERAKRNFQEEQINTRDAKAIAALISEK 778



 Score = 32.7 bits (73), Expect = 0.32
 Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 113 ERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGL-NFGKVDVGRYTDVSTRYKVS 171
           +R     W+V+F++ W + CQ   P +  ++     TGL N G +D  +Y     +  V 
Sbjct: 572 QRKHNEVWMVDFYSPWCHPCQVLMPEWKRMA--RTLTGLINVGSIDCQQYHSFCAQENVQ 629

Query: 172 TSPLTKQLP 180
             P  +  P
Sbjct: 630 RYPEIRFFP 638



 Score = 31.2 bits (69), Expect = 0.93
 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 120 WIVEFFANWSNDCQSFAP-IYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLT 176
           W+V+FFA W   C++  P +    +L Y    L FG +D   +  +   Y +   P T
Sbjct: 471 WLVDFFAPWCPPCRALLPELRRASNLLYG--QLKFGTLDCTVHEGLCNMYNIQAYPTT 526


>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
           [Homo sapiens]
          Length = 406

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 11/90 (12%)

Query: 121 IVEFFANWSNDCQSFAPIYADLS--LKYNCTGLN---FGKVDVGRYTDVSTRYKVSTSPL 175
           +V F+A+W    Q   PI+ + S  +K      N   F +VD  +++D++ RY++S    
Sbjct: 50  LVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRIS---- 105

Query: 176 TKQLPTLILFQGGKEAMRRPQIDKKGRAVS 205
             + PTL LF+ G    R  +  +  +A++
Sbjct: 106 --KYPTLKLFRNGMMMKREYRGQRSVKALA 133


>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
          Length = 280

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 100 IKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVG 159
           ++   D+   E LE D    W++EF+A W   CQ+  P +   +       +N  KVDV 
Sbjct: 31  VRVITDENWRELLEGD----WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVT 86

Query: 160 RYTDVSTRYKVSTSP 174
               +S R+ ++  P
Sbjct: 87  EQPGLSGRFIITALP 101


>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
          Length = 505

 Score = 37.0 bits (84), Expect = 0.017
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 7/71 (9%)

Query: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLP 180
           +VEFFA W   C+  AP Y   + +     +   KVD    T+   +Y VS        P
Sbjct: 49  LVEFFAPWCGHCKRLAPEYEAAATRLKGI-VPLAKVDCTANTNTCNKYGVS------GYP 101

Query: 181 TLILFQGGKEA 191
           TL +F+ G+EA
Sbjct: 102 TLKIFRDGEEA 112



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 9/88 (10%)

Query: 110 EELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYN-CTGLNFGKVDVGRYTDVSTRY 168
           +E+  ++    ++EF+A W   C++  P Y +L  K +    +   K+D     DV + Y
Sbjct: 387 DEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMD-ATANDVPSPY 445

Query: 169 KVS------TSPLTKQLPTLILFQGGKE 190
           +V        SP  K+L     ++GG+E
Sbjct: 446 EVRGFPTIYFSPANKKLNPK-KYEGGRE 472


>gi|50592994 thioredoxin [Homo sapiens]
          Length = 105

 Score = 36.2 bits (82), Expect = 0.029
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 13/94 (13%)

Query: 100 IKYFNDKTIDEEL---ERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKV 156
           +K    KT  +E      DK V  +V+F A W   C+   P +  LS KY  + + F +V
Sbjct: 2   VKQIESKTAFQEALDAAGDKLV--VVDFSATWCGPCKMIKPFFHSLSEKY--SNVIFLEV 57

Query: 157 DVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKE 190
           DV    DV++  +V      K +PT   F+ G++
Sbjct: 58  DVDDCQDVASECEV------KCMPTFQFFKKGQK 85


>gi|94421469 disulfide isomerase [Homo sapiens]
          Length = 360

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 8/79 (10%)

Query: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLP 180
           +V F+  W     S AP +  L   +    L+F  +D  +++ +STR+       T  +P
Sbjct: 212 LVLFYTPWCRFSASLAPHFNSLPRAF--PALHFLALDASQHSSLSTRFG------TVAVP 263

Query: 181 TLILFQGGKEAMRRPQIDK 199
            ++LFQG K   R    D+
Sbjct: 264 NILLFQGAKPMARFNHTDR 282


>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
          Length = 440

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 11/87 (12%)

Query: 120 WIVEFFANWSNDCQSFAPIY--ADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTK 177
           W+VEF+A W   CQ   P +  A  +LK     +  G VD  ++  +  +Y V      +
Sbjct: 46  WLVEFYAPWCGHCQRLTPEWKKAATALK---DVVKVGAVDADKHHSLGGQYGV------Q 96

Query: 178 QLPTLILFQGGKEAMRRPQIDKKGRAV 204
             PT+ +F   K      Q  + G A+
Sbjct: 97  GFPTIKIFGSNKNRPEDYQGGRTGEAI 123



 Score = 32.3 bits (72), Expect = 0.42
 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 9/78 (11%)

Query: 115 DKRVTWIVEFFANWSNDCQSFAPIYADLS--LKYNCTG-LNFGKVDVGRYTDVSTRYKVS 171
           D    W+VEF+A W   C++  P +A  +  +K    G +    VD      +++RY + 
Sbjct: 176 DSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGI- 234

Query: 172 TSPLTKQLPTLILFQGGK 189
                +  PT+ +FQ G+
Sbjct: 235 -----RGFPTIKIFQKGE 247


>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
           sapiens]
          Length = 604

 Score = 33.5 bits (75), Expect = 0.19
 Identities = 13/27 (48%), Positives = 17/27 (62%)

Query: 117 RVTWIVEFFANWSNDCQSFAPIYADLS 143
           R  W VEFFA+W   C +FAP +  L+
Sbjct: 58  RSAWAVEFFASWCGHCIAFAPTWKALA 84


>gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
           sapiens]
          Length = 747

 Score = 33.5 bits (75), Expect = 0.19
 Identities = 13/27 (48%), Positives = 17/27 (62%)

Query: 117 RVTWIVEFFANWSNDCQSFAPIYADLS 143
           R  W VEFFA+W   C +FAP +  L+
Sbjct: 58  RSAWAVEFFASWCGHCIAFAPTWKALA 84


>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
          Length = 166

 Score = 33.1 bits (74), Expect = 0.25
 Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 7/72 (9%)

Query: 103 FNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYT 162
           F D+ ++ E         +V+F A W   C+   P    +  K +   +   KVD+  +T
Sbjct: 70  FQDRVVNSE------TPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVV-MAKVDIDDHT 122

Query: 163 DVSTRYKVSTSP 174
           D++  Y+VS  P
Sbjct: 123 DLAIEYEVSAVP 134


>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
           sapiens]
          Length = 349

 Score = 32.7 bits (73), Expect = 0.32
 Identities = 16/55 (29%), Positives = 28/55 (50%)

Query: 120 WIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSP 174
           W+++F+A W   CQ     +   +       ++ GKVDV +   +S R+ V+T P
Sbjct: 55  WMLKFYAPWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLP 109


>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
          Length = 525

 Score = 32.0 bits (71), Expect = 0.55
 Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 8/70 (11%)

Query: 121 IVEFFANWSNDCQSFAPIYADLS--LKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQ 178
           +VEF+A W   CQ+ AP Y+  +  L      +   KVD     +++  + V+      +
Sbjct: 63  LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVT------E 116

Query: 179 LPTLILFQGG 188
            PTL  F+ G
Sbjct: 117 YPTLKFFRNG 126



 Score = 28.9 bits (63), Expect = 4.6
 Identities = 12/37 (32%), Positives = 20/37 (54%)

Query: 110 EELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKY 146
           E++  D+     V+F+A W   C+  AP +  L+ KY
Sbjct: 399 EQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKY 435


>gi|28372543 protein disulfide isomerase-like, testis expressed
           [Homo sapiens]
          Length = 584

 Score = 31.2 bits (69), Expect = 0.93
 Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 1/45 (2%)

Query: 115 DKRVTWIVEFFANWSNDCQSFAPIYADLSLKY-NCTGLNFGKVDV 158
           DK     V F+A WS  C+   P+  +L  KY N + +   K+DV
Sbjct: 403 DKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDV 447


>gi|237648961 thioredoxin domain containing 16 isoform 2 [Homo
           sapiens]
          Length = 820

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTG-LNFGKVDVGRYTDVSTRYKVSTSPLTK 177
           IV F+A W     +F   Y D+++K   T  +   +++   ++DV T+  V+  P+ K
Sbjct: 406 IVLFYAGWQAVSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIK 463


>gi|237648959 thioredoxin domain containing 16 isoform 1 [Homo
           sapiens]
          Length = 825

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 121 IVEFFANWSNDCQSFAPIYADLSLKYNCTG-LNFGKVDVGRYTDVSTRYKVSTSPLTK 177
           IV F+A W     +F   Y D+++K   T  +   +++   ++DV T+  V+  P+ K
Sbjct: 411 IVLFYAGWQAVSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIK 468


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)

Query: 210   EENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTP 246
             E+ ++ E +L  +YQ+   ++KAGDNI  E PV   P
Sbjct: 21058 EQTMLPELDLRGIYQKLV-IAKAGDNIKVEIPVLGRP 21093


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)

Query: 210   EENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTP 246
             E+ ++ E +L  +YQ+   ++KAGDNI  E PV   P
Sbjct: 14753 EQTMLPELDLRGIYQKLV-IAKAGDNIKVEIPVLGRP 14788


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)

Query: 210   EENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTP 246
             E+ ++ E +L  +YQ+   ++KAGDNI  E PV   P
Sbjct: 14686 EQTMLPELDLRGIYQKLV-IAKAGDNIKVEIPVLGRP 14721


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)

Query: 210   EENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTP 246
             E+ ++ E +L  +YQ+   ++KAGDNI  E PV   P
Sbjct: 14561 EQTMLPELDLRGIYQKLV-IAKAGDNIKVEIPVLGRP 14596


>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
          Length = 1235

 Score = 29.3 bits (64), Expect = 3.6
 Identities = 18/80 (22%), Positives = 36/80 (45%)

Query: 157  DVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIRE 216
            D+G +        V   P    + TL+L    K   R   +DKK   V     + +V +E
Sbjct: 931  DLGNFIRSEEPEVVQRLPPASSVSTLVLAPRPKPRQRLTPVDKKVSFVDIMPHQSDVSQE 990

Query: 217  FNLNELYQRAKKLSKAGDNI 236
             +++E+ +  +K+ +  D++
Sbjct: 991  GSVDEVKENTEKMQQGKDDV 1010


>gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]
          Length = 698

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 8/24 (33%), Positives = 16/24 (66%)

Query: 120 WIVEFFANWSNDCQSFAPIYADLS 143
           W+V+F+++W   C  +AP +  L+
Sbjct: 82  WLVQFYSSWCGHCIGYAPTWRALA 105


>gi|134152674 rabaptin, RAB GTPase binding effector protein 1
           isoform 2 [Homo sapiens]
          Length = 829

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 2/89 (2%)

Query: 29  SALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSMFLMT 88
           S L   A  L ++L  +CH L  +R+  N     W++       S  ++M++ + M ++ 
Sbjct: 246 SVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVL 305

Query: 89  CKPPLYMGPEYIKYFNDKTIDEELERDKR 117
               L    E  K   D+  DE+   +KR
Sbjct: 306 TSEQLRQVEELKK--KDQEDDEQQRLNKR 332


>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
           1 [Homo sapiens]
          Length = 862

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 2/89 (2%)

Query: 29  SALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSMFLMT 88
           S L   A  L ++L  +CH L  +R+  N     W++       S  ++M++ + M ++ 
Sbjct: 246 SVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVL 305

Query: 89  CKPPLYMGPEYIKYFNDKTIDEELERDKR 117
               L    E  K   D+  DE+   +KR
Sbjct: 306 TSEQLRQVEELKK--KDQEDDEQQRLNKR 332


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,077,027
Number of Sequences: 37866
Number of extensions: 417356
Number of successful extensions: 931
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 889
Number of HSP's gapped (non-prelim): 50
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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