Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 22094135
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22094135 DOT1-like, histone H3 methyltransferase [Homo
sapiens]
(1537 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens] 3041 0.0
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 69 3e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 1e-09
gi|91982772 mucin 17 [Homo sapiens] 63 3e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 2e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 60 2e-08
gi|151301154 mucin 6, gastric [Homo sapiens] 58 6e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 57 1e-07
gi|112421108 capicua homolog [Homo sapiens] 52 3e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 52 6e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 51 8e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 51 1e-05
gi|21735548 centrosomal protein 2 [Homo sapiens] 50 1e-05
gi|62243374 MAD1-like 1 protein [Homo sapiens] 49 3e-05
gi|62243369 MAD1-like 1 protein [Homo sapiens] 49 3e-05
gi|62243332 MAD1-like 1 protein [Homo sapiens] 49 3e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 49 5e-05
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 48 6e-05
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 48 6e-05
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 48 6e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 48 6e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 48 6e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 48 6e-05
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 48 6e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 48 6e-05
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 48 8e-05
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 48 8e-05
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 47 1e-04
gi|34878777 ring finger protein 20 [Homo sapiens] 47 1e-04
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 47 2e-04
>gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]
Length = 1537
Score = 3041 bits (7884), Expect = 0.0
Identities = 1537/1537 (100%), Positives = 1537/1537 (100%)
Query: 1 MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL 60
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
Sbjct: 1 MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL 60
Query: 61 IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT 120
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
Sbjct: 61 IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT 120
Query: 121 DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK 180
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK
Sbjct: 121 DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK 180
Query: 181 HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV 240
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
Sbjct: 181 HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV 240
Query: 241 NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK 300
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
Sbjct: 241 NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK 300
Query: 301 GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGP 360
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGP
Sbjct: 301 GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGP 360
Query: 361 EGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTA 420
EGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTA
Sbjct: 361 EGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTA 420
Query: 421 NPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT 480
NPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT
Sbjct: 421 NPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPT 480
Query: 481 PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQK 540
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQK
Sbjct: 481 PPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQK 540
Query: 541 EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLL 600
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLL
Sbjct: 541 EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLL 600
Query: 601 KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK 660
KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
Sbjct: 601 KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK 660
Query: 661 SCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGY 720
SCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGY
Sbjct: 661 SCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGY 720
Query: 721 ELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIV 780
ELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIV
Sbjct: 721 ELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIV 780
Query: 781 LRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL 840
LRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL
Sbjct: 781 LRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL 840
Query: 841 AGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST 900
AGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST
Sbjct: 841 AGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARST 900
Query: 901 PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGA 960
PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGA
Sbjct: 901 PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGA 960
Query: 961 EPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL 1020
EPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL
Sbjct: 961 EPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL 1020
Query: 1021 PEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHG 1080
PEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHG
Sbjct: 1021 PEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHG 1080
Query: 1081 QDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI 1140
QDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI
Sbjct: 1081 QDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI 1140
Query: 1141 TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI 1200
TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI
Sbjct: 1141 TAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARI 1200
Query: 1201 ERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSP 1260
ERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSP
Sbjct: 1201 ERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSP 1260
Query: 1261 LQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGG 1320
LQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGG
Sbjct: 1261 LQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGG 1320
Query: 1321 GLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLK 1380
GLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLK
Sbjct: 1321 GLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLK 1380
Query: 1381 GEGSRGKEAGEGGLPLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLS 1440
GEGSRGKEAGEGGLPLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLS
Sbjct: 1381 GEGSRGKEAGEGGLPLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLS 1440
Query: 1441 GPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS 1500
GPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS
Sbjct: 1441 GPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSS 1500
Query: 1501 VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGGN 1537
VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGGN
Sbjct: 1501 VPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGGN 1537
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 68.9 bits (167), Expect = 3e-11
Identities = 198/806 (24%), Positives = 279/806 (34%), Gaps = 154/806 (19%)
Query: 816 SPSVPGSMKLSPQDPRPLSPGALQLAGEKSS--EKGLRERAYGSSGELIT-SLPISIPLS 872
+P PGS P+ P P++P AL++ G + K L ERA G G I S P + P
Sbjct: 26 TPRPPGS----PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 873 TVQPNKLPVSIPLASVVLPSRAERA----RSTPSPVLQPRDPSSTLEK--------QIGA 920
T +P P S R ERA ++P PV P S T +I A
Sbjct: 82 TSRP---PAS---------GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129
Query: 921 ---------------NAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASL---TPGAEP 962
+A AG+R P + + ++A AG+ L P A P
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189
Query: 963 ATLDE----SSSSGSLFATVGSRSSTPQHPLL---LAQPRNSLPASPAHQLSSSPRLGGA 1015
E S SS S +T + + P L +P + +S A LSS R G +
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 249
Query: 1016 AQGPLPEASKGDLPSDSGF--------SDPESEAKRRI----VFTITTGAGSAKQSPSSK 1063
A+G + P G + P +A + + T + SA SPS+
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309
Query: 1064 HSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPS--LSAGVSPKRRALPSVAGLFTQ-- 1119
S T + PS S + + PS LS +P +A P++A Q
Sbjct: 310 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 369
Query: 1120 ---PSGSPLN-LNSMVSNINQPLEITAISSPETSLKSSPV--PYQDHDQPPVLKKERPLS 1173
P+ PL+ L + L + + +P + S PV P+ PPV P S
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429
Query: 1174 QTNGAHYSP--LTSDEEPGSEDEPSSA----RIERKIATISLESKSPPKTLENGGGLAGR 1227
Q + +P P S SA + +A L+ PP
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489
Query: 1228 KPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPSADAK 1287
+ P+ P S ++ FSP + + ++ A P QA L+ L P+ P A
Sbjct: 490 QALPS--PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA-PLLQVPPS---PPASPT 543
Query: 1288 LAAHPRKGFPGSLSGADG------LSPGTNPANGCTFGGGLAA-DLSLHSFSDGASLPHK 1340
L A R PG + G L+PG P + L+ DL+ HS S S P +
Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS-SSATSTPEE 602
Query: 1341 ------GPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGL 1394
GPE +SP P A +G G G
Sbjct: 603 LRGYDSGPEGGAAASP--------------PPDAELAACHPAAWSRGPAPPLAFRGAPGA 648
Query: 1395 PLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLSGPGL----APAASS 1450
PL P P + + E +A PG+L GP AA+
Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGP---------ESATPAPGALDPGPSPGTSGGKAAAG 699
Query: 1451 AGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSSVPAAAGLVHV 1510
AG ASS ++ LG P G +LQA SV+Q L S A
Sbjct: 700 AGAGASSRSPKQARLGELPLG--------ALQA--------SVVQHLLSRTLLLA----- 738
Query: 1511 SSAATRLTNSHAMGSFSGVAGGTVGG 1536
AA G GG GG
Sbjct: 739 --AAEGAAGGSGGGPGGAEGGGVTGG 762
Score = 40.4 bits (93), Expect = 0.013
Identities = 64/248 (25%), Positives = 86/248 (34%), Gaps = 30/248 (12%)
Query: 786 SQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKS 845
SQ T G P HS + L P P ++ L P P P + L+ +
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 383
Query: 846 SEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS--- 902
+A + + P S P S P + P S P + V PS +++ PS
Sbjct: 384 PS----PQAPNALAVHLLQAPFSPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAA 437
Query: 903 ---------PVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSP 953
P P PS+T Q A LA P A + AL P
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQ-APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496
Query: 954 ASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLG 1013
AS PG P + S L + PQ P +LA P +P SP +SP L
Sbjct: 497 ASF-PGQAPFSPSASLPMSPL------ATPPPQAPPVLAAPLLQVPPSP----PASPTLQ 545
Query: 1014 GAAQGPLP 1021
+ P P
Sbjct: 546 APRRPPTP 553
Score = 32.3 bits (72), Expect = 3.6
Identities = 68/228 (29%), Positives = 86/228 (37%), Gaps = 41/228 (17%)
Query: 813 PYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSSE---------KGLRERAYGSSGEL-- 861
P SP + S PQ P PL+ LQLA + L G+
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505
Query: 862 --ITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQ-PRDPSSTLEKQI 918
SLP+S PL+T P PV V PS SP LQ PR P +
Sbjct: 506 SPSASLPMS-PLATPPPQAPPVLAAPLLQVPPS------PPASPTLQAPRRPPTP----- 553
Query: 919 GANAHGAGSR-SLALAPA---GFSYAGSVAISGA-LAGSPASLTPGAEPATLDESSSSGS 973
G + +G R +LALAP S + S +SG LAG +S T E +S G
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG- 612
Query: 974 LFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLP 1021
G+ +S P L A + PA L+ GA PLP
Sbjct: 613 -----GAAASPPPDAELAACHPAAWSRGPAPPLA----FRGAPGAPLP 651
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 63.5 bits (153), Expect = 1e-09
Identities = 192/806 (23%), Positives = 279/806 (34%), Gaps = 127/806 (15%)
Query: 816 SPSVPGSMKLSPQDPRPLSPGALQLAGEKSS--EKGLRERAYGSSGELIT-SLPISIPL- 871
+P PGS P+ P P++P AL++ G + K L ERA G G I S P + P
Sbjct: 26 TPRPPGS----PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 872 STVQPNKLPVSIPLASVVLPSRAERA----RSTPSPVLQPRDPSSTLEK--------QIG 919
S ++ P S P AS R ERA ++P PV P S T +I
Sbjct: 82 SAGTSSRNPASRPPAS----GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
Query: 920 A---------------NAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASL---TPGAE 961
A +A AG+R P + + ++A AG+ L P A
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
Query: 962 PATLDE----SSSSGSLFATVGSRSSTPQHPLL---LAQPRNSLPASPAHQLSSSPRLGG 1014
P E S SS S +T + + P L +P + +S A LSS R G
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 1015 AAQGPLPEASKGDLPSDSGFS---DPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASA 1071
+A+G + P G P+ R+ G SP + SP +A+
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK---DAAPALGPLSSSPLATPSP-SAAL 313
Query: 1072 RGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMV 1131
+ P+ + TP A SP A PS+ L + P+ P + +
Sbjct: 314 QSQAPPT--LPATPHSSSLTCQLATPLPLAPPSPS--APPSLQTLPSPPATPPSQATTSL 369
Query: 1132 SNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGS 1191
+ + + SP S ++P P PP L PL SP S S
Sbjct: 370 GSPTLQATHSFLPSPPLSPLATPPP----QAPPALALP-PLQAPPSPPASPPLSPLATPS 424
Query: 1192 EDEPSSARIERKIATISLESKSP----------PKTLENGGGLAGRKPAPAGEPVNSSKW 1241
P++ + A S P P + + P+ A P+
Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP- 483
Query: 1242 KSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPSADA----KLAAHPRKGFP 1297
SP + ++ SA P QA L+ L +P + P A A + P FP
Sbjct: 484 ----SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539
Query: 1298 G----SLSGADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSPLSF 1353
G S S + +SP P LAA L +P P + L +P
Sbjct: 540 GQAPFSPSASLPMSPLATPPPQAP--PVLAAPL--------LQVPPSPPASPTLQAPRR- 588
Query: 1354 PSQRGKEGSDANPFLSKRQLDG---------LAGLKGEGSRGKEAGEGGLP--LCGPTDK 1402
P G + S + P L+ G + L G G + P L G D
Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG-YDS 647
Query: 1403 TPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLSGPGLA---PAASSAGGA----- 1454
P G AA + + +L H S PP + PG P A+ G A
Sbjct: 648 GP--EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 705
Query: 1455 ---ASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGS-SVLQSLFSSVPAAAGLVHV 1510
++ G PGP A G+ A S S Q+ +P G +
Sbjct: 706 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP--LGALQA 763
Query: 1511 SSAATRLTNSHAMGSFSGVAGGTVGG 1536
S L+ + + + G AGG+ GG
Sbjct: 764 SVVQHLLSRTLLLAAAEGAAGGSGGG 789
Score = 62.8 bits (151), Expect = 3e-09
Identities = 191/825 (23%), Positives = 279/825 (33%), Gaps = 119/825 (14%)
Query: 755 VGR-PRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGL- 812
VGR P E+ G+ +P R + RP AS RA K
Sbjct: 53 VGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG 112
Query: 813 PYQSPS-VPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPL 871
P SP G+ + P PL L+++ E++ +G A S +L
Sbjct: 113 PVSSPGRASGTTR-----PGPLGQKGLRISAEETVARGKATEAPKRS-----ALSAGARR 162
Query: 872 STVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLA 931
T P S +A + E P+P +PR P+ K + + + + +
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222
Query: 932 LAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLL 991
A S G + PAS + + L + SG S TP+ P
Sbjct: 223 AARRRPSAGGGLQ-------RPASRSLSSSATPLSSPARSGP------SARGTPRAPAHP 269
Query: 992 AQPR-NSLPASPAHQLS-----SSPRLGGAAQGPLPEAS-KGDLPSDSGFSDPESEAKRR 1044
+QP+ L A Q++ ++P LG + PL S L S + + P +
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
Query: 1045 IVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPS--LSAG 1102
+ + T A SPS+ S T + PS S + + PS LS
Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 389
Query: 1103 VSPKRRALPSVAGLFTQ-----PSGSPLN-LNSMVSNINQPLEITAISSPETSLKSSPV- 1155
+P +A P++A Q P+ PL+ L + L + + +P + S PV
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
Query: 1156 -PYQDHDQPPVLKKERPLSQTNGAHYSP--LTSDEEPGSEDEPSSA----RIERKIATIS 1208
P+ PPV P SQ + +P P S SA + +A
Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 1209 LESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALS 1268
L+ PP + P+ P S ++ FSP + + ++ A P QA L+
Sbjct: 510 LQLAKPPPQAPPALATPPLQALPS--PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 567
Query: 1269 QNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADG------LSPGTNPANGCTFGGGL 1322
L P+ P A L A R PG + G L+PG P + L
Sbjct: 568 A-PLLQVPPS---PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 623
Query: 1323 AA-DLSLHSFSDGASLPHK------GPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDG 1375
+ DL+ HS S S P + GPE +SP P
Sbjct: 624 SGPDLAGHS-SSATSTPEELRGYDSGPEGGAAASP--------------PPDAELAACHP 668
Query: 1376 LAGLKGEGSRGKEAGEGGLPLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPP 1435
A +G G G PL P P + + E +A P
Sbjct: 669 AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP---------ESATPAP 719
Query: 1436 GSLLSGPGL----APAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGS 1491
G+L GP AA+ AG ASS ++ LG P G +LQA
Sbjct: 720 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG--------ALQA-------- 763
Query: 1492 SVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGG 1536
SV+Q L S A AA G GG GG
Sbjct: 764 SVVQHLLSRTLLLA-------AAEGAAGGSGGGPGGAEGGGVTGG 801
Score = 40.8 bits (94), Expect = 0.010
Identities = 84/330 (25%), Positives = 114/330 (34%), Gaps = 53/330 (16%)
Query: 704 LSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKL 763
L++ SP ++ QA + + P S T Q LA+PL P P P L
Sbjct: 304 LATPSPSAALQSQAPPT----LPATPHSSSLTCQ-LATPL-----PLAPPSPSAP--PSL 351
Query: 764 SGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSM 823
L +P T S A L G P HS + L P P ++
Sbjct: 352 QTLPSPPATPPSQATTSL-----------GSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
Query: 824 KLSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSI 883
L P P P + L+ + +A + + P S P S P + P S
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPS----PQAPNALAVHLLQAPFSPPPS--PPVQAPFSP 454
Query: 884 PLASVVLPSRAERARSTPS------------PVLQPRDPSSTLEKQIGANAHGAGSRSLA 931
P + V PS +++ PS P P PS+T Q A LA
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ-APPPLAAPPLQLA 513
Query: 932 LAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLL 991
P A + AL PAS PG P + S L + PQ P +L
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASF-PGQAPFSPSASLPMSPL------ATPPPQAPPVL 566
Query: 992 AQPRNSLPASPAHQLSSSPRLGGAAQGPLP 1021
A P +P SP +SP L + P P
Sbjct: 567 AAPLLQVPPSP----PASPTLQAPRRPPTP 592
Score = 32.7 bits (73), Expect = 2.8
Identities = 41/164 (25%), Positives = 57/164 (34%), Gaps = 11/164 (6%)
Query: 332 PKLREEQEAARRRQQRESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVKKPSP 391
P R R+ S S +T P + A + A + +AT P
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT---PLS 250
Query: 392 SKARK-KKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAASSPQ 450
S AR R A + +PK + P + + A AL + S A SP
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 451 DAYRSPHSPFYQLPP---SVQRHSPNPLLVAP----TPPALQKL 487
A +S P P S+ PL +AP PP+LQ L
Sbjct: 311 AALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL 354
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 62.8 bits (151), Expect = 3e-09
Identities = 137/657 (20%), Positives = 239/657 (36%), Gaps = 100/657 (15%)
Query: 744 DQEVVPCTPSHVGRPRLE---KLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASEL 800
D + TPS P + +A+ + + LS + + ++ P +E+
Sbjct: 439 DTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEV 498
Query: 801 HSRAEHTKENG-LPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSG 859
+S T G P S SV +M ++ + LS + + ++ E + S+
Sbjct: 499 NSMPTSTPSEGSTPLTSMSV-STMPVASSEASTLSTTPVDTSTPVTTSS---EASSSSTT 554
Query: 860 ELITSLPISIPLSTVQP-NKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQI 918
TS+P S P P +PVS L V+ S A +TP+ D ++ +
Sbjct: 555 PEGTSIPTSTPSEGSTPLTNMPVSTRL---VVSSEASTTSTTPA------DSNTFVTTSS 605
Query: 919 GANAHGAGSRSLALAPAGFSYAG----SVAISGALAGSPASLTPGAEP------------ 962
A++ + ++ + +S G S+++S L S + T P
Sbjct: 606 EASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTE 665
Query: 963 ----ATLDESSSSGSLFATVGSR--SSTPQHPLLLAQPR----------NSLPASPAHQL 1006
+T E +S + T GS +S P + L+A S P + + +
Sbjct: 666 ATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEA 725
Query: 1007 SSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSP 1066
SSSP A P S+G P S P S+ ++ A + +P +
Sbjct: 726 SSSPTTADGASMPTSTPSEGSTPLT---SMPVSK-----TLLTSSEASTLSTTPLDTSTH 777
Query: 1067 LTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLN 1126
+T S C P+ + + TPS SP ++P T P S L+
Sbjct: 778 ITTSTEASCSPTTTEGT-------SMPISTPSEG---SPLLTSIPVSITPVTSPEASTLS 827
Query: 1127 LNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSD 1186
+ SN + T +SS T + + +P + + P+S T A + T
Sbjct: 828 TTPVDSN-SPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLS 886
Query: 1187 EEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFS 1246
P P T S E++S P T E G + P P+ S +T
Sbjct: 887 TTPVDTSTP---------VTNSTEARSSPTTSE-GTSMPTSTPGEGSTPLTSMPDSTT-- 934
Query: 1247 PISDIGLAKSADSPLQASSALSQNSLFTFRPALEE----PSADAKLAAHPRKGFPGS--- 1299
P+ + +P+ S+ ++ ++ T P E P++ P P S
Sbjct: 935 PVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTL 994
Query: 1300 LSGADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQ 1356
++ ++ + T P + T L + ++ +S P P A G S P S PS+
Sbjct: 995 VANSEASTLSTTPVDSNT---------PLTTSTEASSPP---PTAEGTSMPTSTPSE 1039
Score = 53.9 bits (128), Expect = 1e-06
Identities = 160/802 (19%), Positives = 276/802 (34%), Gaps = 128/802 (15%)
Query: 797 ASELHSRAEHTKENGLPYQSPS-VPGSMKLSPQDPRPL-SPGALQLAGEKSSEKGLRERA 854
++E S K+ +P +PS V S+ P+ S A L+ + L +
Sbjct: 2608 STETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTS 2667
Query: 855 YGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTL 914
G+S T+ S+P ST P++ L S L + +E + + +PV P +T
Sbjct: 2668 TGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPV-DTSTPVTTS 2726
Query: 915 EKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSL 974
+ + G+ P+ GS ++ L +TL +SS S
Sbjct: 2727 AEASSSPTTAEGTSMRISTPSD----GSTPLTSILV------------STLPVASSEAST 2770
Query: 975 FATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGF 1034
+T + S+P + + + SSSP P PS++
Sbjct: 2771 VSTTAVDT--------------SIPVTTSTEASSSPTTAEVTSMPT------STPSET-- 2808
Query: 1035 SDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQ------DSRRRGR 1088
S P + ++ AG+ +P +P+T S + P+ + + G
Sbjct: 2809 STPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGS 2868
Query: 1089 RKRAS--------AGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEI 1140
S A + + + +P ++P T+ S SP I+ P E
Sbjct: 2869 TLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTS--TEGSSSPTTAEGTSMPISTPSE- 2925
Query: 1141 TAISSPETSLKSSPVPYQDHDQPPV----LKKERPLSQTNGAHYSPLTSDEEPGSEDEPS 1196
+S+P TS+ S VP + + + P++ + A SP T++ P
Sbjct: 2926 --VSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAE----GTSMPI 2979
Query: 1197 SARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKS 1256
S ER+ S+ + P L+ R PA PV +S +++ SP + G
Sbjct: 2980 STPGERRTPLTSMSVSTMPVASSEASTLS-RTPADTSTPVTTST-EASSSPTTAEGTGIP 3037
Query: 1257 ADSPLQASSALSQNSLFTFRPALEEPS------ADAKLAAHPRKGFPGSLSGADG----- 1305
+P + S+ L+ + T A+ E S D+ S + A+G
Sbjct: 3038 ISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPI 3097
Query: 1306 --LSPGTNPANGCTFGGGLAADLSLHSFSD---GASLP-------HKGPEAA-GLSSPLS 1352
S G+ P G ++ + S S P H P + G S P S
Sbjct: 3098 STYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTS 3157
Query: 1353 FPSQR---------------GKEGS--------DANPFLSKRQLDGLAGLKGEGSRGKEA 1389
PS+ E S + P + + +G
Sbjct: 3158 TPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTP 3217
Query: 1390 GEGGLPLCG-PTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPP-------GSLLSG 1441
EG PL P TP+ S +A+ VD A++ PP +
Sbjct: 3218 SEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPS 3277
Query: 1442 PGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVA-GSSVLQSLFSS 1500
G P S + A + S L P + S ++ +A G+S+ S +S
Sbjct: 3278 EGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSE 3337
Query: 1501 VPAAAGLVHVSSAATRLTNSHA 1522
+ L ++S + T + +S A
Sbjct: 3338 --GSTPLTNMSFSTTPVVSSEA 3357
Score = 52.0 bits (123), Expect = 4e-06
Identities = 153/710 (21%), Positives = 247/710 (34%), Gaps = 145/710 (20%)
Query: 868 SIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPV---------LQPRDPSSTLE-KQ 917
SIP ST+ P++ S L + +E + + +PV + P T E
Sbjct: 2268 SIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTS 2327
Query: 918 IGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASL-TP-------GAEPATLDESS 969
+ + G+ L P + S S L+ +PA TP G+ P T D++S
Sbjct: 2328 MPTSTSSEGNTPLTRMPVSTTMVASFETS-TLSTTPADTSTPVTTYSQAGSSPTTADDTS 2386
Query: 970 SSGSLFATVGSRSSTP-------QHPLLLAQPRN--------SLPASPAHQLSSSPRLGG 1014
S + S STP P++ ++ S P + + + SSSP
Sbjct: 2387 MPTSTY----SEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAE 2442
Query: 1015 AAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGD 1074
P S+G P S P S +++ AG+ +P +P+T S
Sbjct: 2443 GTSIPTSPPSEGTTPLASM---PVSTTP-----VVSSEAGTLSTTPVDTSTPMTTSTEAS 2494
Query: 1075 CVPSHGQDSRRRGRRKRASAGTPSL-SAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSN 1133
P+ +D AS G+ L S VS A P + L T +P++ NS V
Sbjct: 2495 SSPTTAEDI--VVPISTASEGSTLLTSIPVSTTPVASPEASTLST----TPVDSNSPV-- 2546
Query: 1134 INQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSED 1193
+ T ISS TS + + +P + + + P+S PL S E
Sbjct: 2547 ----VTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVST------KPLASSEASTLST 2596
Query: 1194 EPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGL 1253
P I T S E+ S P T K T PIS
Sbjct: 2597 TPVDTSIP---VTTSTETSSSPTTA-----------------------KDTSMPIS---- 2626
Query: 1254 AKSADSPLQASSALSQNSLFTFRPALEEPS------ADAKLAAHPRKGFPGSLSGADGLS 1307
+P + S++L+ + T A E S D + G S + A+G S
Sbjct: 2627 -----TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSS 2681
Query: 1308 -PGTNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANP 1366
P + P T + +L + S+ ++L S+P++ ++ + A
Sbjct: 2682 MPTSTPGERSTPLTNILVSTTLLANSEASTL---STTPVDTSTPVTTSAEASSSPTTA-- 2736
Query: 1367 FLSKRQLDGLAGLKGEGSRGKEAGEGGLPLCGPTDKT-PLLSGKAAKARDREVDLKNGHN 1425
+G R +G PL T P+ S +A+ VD
Sbjct: 2737 -------------EGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVT 2783
Query: 1426 LFISAAAVPPGS----------------LLSGP-GLAPAASSAGGAASSAQTHRSFLGPF 1468
A++ P + L S P P ASS G S+ S P
Sbjct: 2784 TSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTS--TPV 2841
Query: 1469 PPGPQFALGPMSLQANLGSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLT 1518
+ + P + + + ++ +S +L +S+P + V S A+T T
Sbjct: 2842 TTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLST 2891
Score = 50.8 bits (120), Expect = 1e-05
Identities = 131/657 (19%), Positives = 231/657 (35%), Gaps = 84/657 (12%)
Query: 730 SSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSG---LAAPDYTRLSPAKIVLRRHLS 786
SS T + + P+ TPS V P L +A + + LS + R ++
Sbjct: 2907 SSSPTTAEGTSMPIS------TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVT 2960
Query: 787 QDHTVPGRPAASELHSRAEHTK-ENGLPYQSPSVPGSMKLSPQDPRPLS--PGALQLAGE 843
P +E S T E P S SV +M ++ + LS P
Sbjct: 2961 TSAEASSSPTTAEGTSMPISTPGERRTPLTSMSV-STMPVASSEASTLSRTPADTSTPVT 3019
Query: 844 KSSEKGLRER-AYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS 902
S+E A G+ + T S PL+++ + PV+IP AS + + + + S
Sbjct: 3020 TSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD----SNS 3075
Query: 903 PVLQPRDPSSTLEKQIGA----NAHGAGSRSLALAPAGFSYAGSVAISGALAGSPAS--- 955
PV+ + SS+ G + + GS L P + S AIS L+ +P
Sbjct: 3076 PVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS-TLSTTPVDTST 3134
Query: 956 -LTPGAEPATLDESSSSGSLFATVGSRSSTP------QHPLLLAQPRNSLPASPAHQLSS 1008
+T E + +S S+ + S STP L+++ ++L A+P +
Sbjct: 3135 PVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTP 3194
Query: 1009 SPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLT 1068
A E + + S P + ++ A +P ++PLT
Sbjct: 3195 VTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLT 3254
Query: 1069 ASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQP--SGSPLN 1126
S P + + + TP S VS A + L T P + +P+
Sbjct: 3255 TSTEASSSPPTAEGT-SMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVT 3313
Query: 1127 LNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKE------------RPLSQ 1174
S S+ + T++ + S S+P+ PV+ E P++
Sbjct: 3314 TYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTT 3373
Query: 1175 TNGAHYSPLTSDEEPGSEDEPSSARI--------------------------ERKIATIS 1208
+ A SP T++ PS + T S
Sbjct: 3374 STEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTS 3433
Query: 1209 LESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALS 1268
E+ S P T+ G L + P++ +T P++ + + +P+ S+ ++
Sbjct: 3434 TEASSSP-TIAEGTSLPTSTTSEGSTPLSIMPLSTT--PVASSEASTLSTTPVDTSTPVT 3490
Query: 1269 QNSLFTFRPALEE----PSADAKLAAHPRKGFPGS---LSGADGLSPGTNPANGCTF 1318
+S P E P++ A + P P S ++ ++ + T P + TF
Sbjct: 3491 TSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTF 3547
Score = 50.4 bits (119), Expect = 1e-05
Identities = 148/721 (20%), Positives = 257/721 (35%), Gaps = 88/721 (12%)
Query: 727 SRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLS 786
S P++ + T +++P +E + T + V L + Y K+ + L+
Sbjct: 137 SSPTTPEGTDVPMSTP-SEESISSTMAFVSTAPLPSFEAYTSLTY------KVDMSTPLT 189
Query: 787 QDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSS 846
P E + + T G + +MK++ + L ++++ +
Sbjct: 190 TSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTI 249
Query: 847 EKGLRERAYGSSGELITSLPISIPLSTVQP-NKLPVSIPLASVVLPSRAERARSTPS--- 902
+ G SL S P P ++P+S+ L V+ S A +TP+
Sbjct: 250 SAQASSSPTTAEGP---SLSNSAPSGGSTPLTRMPLSVML---VVSSEASTLSTTPAATN 303
Query: 903 -PVLQPRDPSS---TLE-KQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPAS-- 955
PV+ + SS T E I + + GS L PA + +S L+ +P
Sbjct: 304 IPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMS-TLSITPVDTS 362
Query: 956 --LTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLG 1013
+T EP++L ++ + S+ + S ST P ++P S SS
Sbjct: 363 TLVTTSTEPSSLPTTAEATSMLTSTLSEGST---------PLTNMPVSTILVASSE---- 409
Query: 1014 GAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARG 1073
+ +P SK + + S S + A+ + T T GS + + AS+
Sbjct: 410 ASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEA 469
Query: 1074 DCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSN 1133
+ + DS+ + T S A SP + S+ +PL S+ +
Sbjct: 470 SNLSTTPVDSK--------TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVST- 520
Query: 1134 INQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGS-- 1191
+ SS ++L ++PV D P E S T S TS GS
Sbjct: 521 ------MPVASSEASTLSTTPV---DTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTP 571
Query: 1192 -EDEPSSARI---------------ERKIATISLESKSPPKTLENGGGLAGRKPAPAGEP 1235
+ P S R+ T S E+ S T E G + + G
Sbjct: 572 LTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAE-GTSMPTSTYSERGTT 630
Query: 1236 VNSSKWKSTFSPISDIGLAKS--ADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPR 1293
+ S +T S+ + DS +++ S T P++ + P
Sbjct: 631 ITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPL 690
Query: 1294 KGFPGS---LSGADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSP 1350
P + ++ ++ + T P + T S + +DGAS+P P S+P
Sbjct: 691 TSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEG--STP 748
Query: 1351 L-SFPSQRGKEGSDANPFLSKRQLDGLAGL--KGEGSRGKEAGEG-GLPLCGPTDKTPLL 1406
L S P + S LS LD + E S EG +P+ P++ +PLL
Sbjct: 749 LTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLL 808
Query: 1407 S 1407
+
Sbjct: 809 T 809
Score = 48.1 bits (113), Expect = 6e-05
Identities = 141/652 (21%), Positives = 222/652 (34%), Gaps = 126/652 (19%)
Query: 795 PAASELHSRAEHTKENG--LPYQSPSVPGSMKLS--PQDPRP-LSPGALQLAGEKSSEKG 849
P + +R+ T G +P +PS G+ L+ P P LS A L+
Sbjct: 1720 PVTTSTEARSSPTTSEGTSMPNSTPS-EGTTPLTSIPVSTTPVLSSEASTLSATPIDTST 1778
Query: 850 LRERAYGSSGELITSLPISIPLSTVQPNKLPV-SIPLA-SVVLPSRAERARSTP----SP 903
+ ++ T+ SIP ST+ P+ S P++ ++V S A +TP SP
Sbjct: 1779 PVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSP 1838
Query: 904 VLQPR----DPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPA-SLTP 958
V+ P+ I + GS +L P + S + + L+ +PA + TP
Sbjct: 1839 VVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVAS-SETNTLSTTPAVTSTP 1897
Query: 959 -------GAEPATLDESSSSGS-------------LFATVGSRSSTPQHPLLLAQPRNSL 998
+ P T D SS S + T + S LA R
Sbjct: 1898 VTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRT-- 1955
Query: 999 PASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQ 1058
P + Q SSSP P P S+G S P + +++ A +
Sbjct: 1956 PVTTYSQASSSPTTADGTSMPTPAYSEG--------STPLTSMPLSTTLVVSSEASTLST 2007
Query: 1059 SPSSKHSPLTASARGDCVPSHGQ----DSRRRGRRKRASAGTP-SLSAGVSPKRRALPSV 1113
+P +P T S G P+ + R AG P S + VS + L +
Sbjct: 2008 TPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTT 2067
Query: 1114 -------------AGLFTQPSGSPLNLNS------MVSNINQPLEITAISSPETS-LKSS 1153
A GS + +++ ++++I PL T ++SPE S L ++
Sbjct: 2068 PVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSI--PLSTTPVASPEASTLSTT 2125
Query: 1154 PVPYQDHDQPPVLKKE---RPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIA----- 1205
PV D + P + E P+ + + SD P S + A
Sbjct: 2126 PV---DSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLS 2182
Query: 1206 ----------TISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAK 1255
T S E++S P T E G + P+ P S P+S + +
Sbjct: 2183 TTPVDTSTPVTNSTEARSSPTTSE-GTSMPTSTPSEGSTPFTS-------MPVSTMPVVT 2234
Query: 1256 SADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANG 1315
S S L A+ + + T A P+ G+ LS GT P
Sbjct: 2235 SEASTLSATPVDTSTPVTTSTEATSSPTT-----------AEGTSIPTSTLSEGTTPLTS 2283
Query: 1316 CTFGGGLAADLSLHS-----------FSDGASLPHKGPEAAGLSSPLSFPSQ 1356
L A+ + + F+ P A G S P S S+
Sbjct: 2284 IPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSE 2335
Score = 38.1 bits (87), Expect = 0.066
Identities = 150/705 (21%), Positives = 249/705 (35%), Gaps = 139/705 (19%)
Query: 862 ITSLPISIPL------STVQPNKLPVSIPLA-SVVLPSRAERARSTPSPVLQPRDPSSTL 914
+TS P+S L ST+ + + PL S S A T P P + S+ L
Sbjct: 985 LTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPL 1044
Query: 915 EKQIGANAHGAGSRS--LALAPAG-------FSYAGSVAISGALAGSPASL-TPGAEPAT 964
+ + A S + L+ PA +S A S + + P S + G+ P T
Sbjct: 1045 TRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLT 1104
Query: 965 LDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEAS 1024
S+ + + + S+TP S+P + + + SSSP P S
Sbjct: 1105 SVPVSTRLVVSSEASTLSTTPVD--------TSIPVTTSTEASSSPTTAEGTSIPTSPPS 1156
Query: 1025 KGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSR 1084
+G P S P S + L S+ + + + DS+
Sbjct: 1157 EGTTPLAS--------------------------MPVS--TTLVVSSEANTLSTTPVDSK 1188
Query: 1085 RRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAIS 1144
+ S + + P A + + P+ +P ++ ++++ P+ T ++
Sbjct: 1189 TQ--------------VATSTEASSPPPTAEVTSMPTSTPGERSTPLTSM--PVRHTPVA 1232
Query: 1145 SPETS-LKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGS---EDEPSSARI 1200
S E S L +SPV D P E S T S TS GS P S +
Sbjct: 1233 SSEASTLSTSPV---DTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTL 1289
Query: 1201 -----ERKIATISLESKSPPKTLENGGGLAGRKPAPA-GEPVNSSKWKSTFSPISDIGLA 1254
+ T +++K P T P PA G + +S + +P++ I
Sbjct: 1290 VTSPEASTLLTTPVDTKGPVVTSNE----VSSSPTPAEGTSMPTSTYSEGRTPLTSI--- 1342
Query: 1255 KSADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLS-PGTNPA 1313
++ L ASSA+S L D S + ++G S P +NP+
Sbjct: 1343 -PVNTTLVASSAIS---------ILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPS 1392
Query: 1314 NGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQL 1373
G T + ++ P EA+ LS+ S G ++A S
Sbjct: 1393 EGTTPLTSIPV----------STTPVVSSEASTLSATPVDTSTPGTTSAEATS--SPTTA 1440
Query: 1374 DGLAGLKGEGSRGKEAGEGGLPLCG-PTDKTPLLSGKAAKARDREVDLKNGHNLFISAAA 1432
+G++ S GK PL P TP+ + +A+ VD + + S A
Sbjct: 1441 EGISIPTSTPSEGK------TPLKSIPVSNTPVANSEASTLSTTPVD--SNSPVVTSTAV 1492
Query: 1433 VPPGSLLSGPGLAPAASSAGGAA------SSAQTHRSFLGPFPPGPQFALGPMSLQANLG 1486
+ G +A + S G A S+ S + P P++ +
Sbjct: 1493 SSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQAS 1552
Query: 1487 S----VAGSSVLQSLFS-------SVPAAAGLVHVSSAATRLTNS 1520
S G+S+ S +S S+P + LV VSS A L+ +
Sbjct: 1553 SSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLV-VSSEANTLSTT 1596
Score = 38.1 bits (87), Expect = 0.066
Identities = 90/422 (21%), Positives = 151/422 (35%), Gaps = 48/422 (11%)
Query: 818 SVPGSMKLSPQDPR-PLSPGALQLAGEKSSEKGLRERAYGSSGE-LITSLPISIPLSTVQ 875
S ++ SP D P++ A + ++E + S G L+TS+P+S L T
Sbjct: 1234 SEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP 1293
Query: 876 PNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPA 935
++ P+ + + S+P+P P+ST + G L P
Sbjct: 1294 EASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTST---------YSEGRTPLTSIPV 1344
Query: 936 GFSYAGSVAISGALAGSPAS----LTPGAEPATLDESSSSGSLFATVGSRSSTP------ 985
+ S AIS L+ +P +T E + +S S+ + S +TP
Sbjct: 1345 NTTLVASSAIS-ILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPV 1403
Query: 986 --------QHPLLLAQP-RNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSD 1036
+ L A P S P + + + +SSP P S+G P S
Sbjct: 1404 STTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLK---SI 1460
Query: 1037 PESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGT 1096
P S + A + +P +SP+ S P+ + + + T
Sbjct: 1461 PVSNTP-----VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT-SIAISTPSEGST 1514
Query: 1097 PSLSAGVSPKRRALPSVAGLFTQP--SGSPLNLNSMVSNINQPLEITAISSPETSLKSSP 1154
S VS A + L T P + +P+ S S+ + T++ + S S+P
Sbjct: 1515 ALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTP 1574
Query: 1155 VPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEE-PGSEDEPSSARIERKIATISLESKS 1213
+ PV S+ N +P+ S + S + SS E TIS S+
Sbjct: 1575 L-----TSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEG 1629
Query: 1214 PP 1215
P
Sbjct: 1630 SP 1631
Score = 36.2 bits (82), Expect = 0.25
Identities = 62/274 (22%), Positives = 97/274 (35%), Gaps = 36/274 (13%)
Query: 952 SPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPR 1011
S +TP T + +S S +LF + +S+P P +P S + S S
Sbjct: 106 SSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTP-----EGTDVPMSTPSEESISST 160
Query: 1012 LGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASA 1071
+ + P LPS ++ + T +T A S+ +P S P + ++
Sbjct: 161 MAFVSTAP--------LPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNS 212
Query: 1072 RGDCVPSHGQDSRRRGRRKRA--------SAGTP---SLSAGVSPKRRALPSVAGLFTQP 1120
G + S + A TP S A SP PS++ + P
Sbjct: 213 EGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSN--SAP 270
Query: 1121 SGSPLNLNSMVSNINQPLEITAISSPETS-LKSSPVPYQDHDQPPVLKKERPLSQTNGAH 1179
SG L M PL + + S E S L ++P + P + E S T
Sbjct: 271 SGGSTPLTRM------PLSVMLVVSSEASTLSTTPAA---TNIPVITSTEASSSPTTAEG 321
Query: 1180 YSPLTSDEEPGSEDEPSSARIERKIATISLESKS 1213
S TS GS S+ +AT + + S
Sbjct: 322 TSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLS 355
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 59.7 bits (143), Expect = 2e-08
Identities = 134/557 (24%), Positives = 200/557 (35%), Gaps = 108/557 (19%)
Query: 816 SPSVPGSMKLSPQDPRPLSPGALQLAGEKSS--EKGLRERAYGSSGELITSLPISIPLST 873
+P PGS P+ P P++P AL++ G + K L ERA G G
Sbjct: 26 TPRPPGS----PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG-------------- 67
Query: 874 VQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALA 933
+P A RA T S R+P+S A G G R+
Sbjct: 68 --------------ATIPESAPRAGPTRSAGTSSRNPASR------PPASGRGERA---P 104
Query: 934 PAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATV--GSRSSTPQHPLLL 991
PA + G V+ G +G+ P L + S TV G + P+ L
Sbjct: 105 PAKNTSPGPVSSPGRASGT-------TRPGPLGQKGLRISAEETVARGKATEAPKRSALS 157
Query: 992 AQPRNS----LPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVF 1047
A R P +P+ ++ R G G LP P+ S P +E R+ V
Sbjct: 158 AGARRDTSGPTPGTPSPAMARRSRAAGTEVG-LPR------PAPSARPRPPTEGPRKSV- 209
Query: 1048 TITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTP-SLSAGVSPK 1106
S +S+HS S PS G +R R +S+ TP S A P
Sbjct: 210 -----------SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 1107 RRALPSVAGLFTQPSGSPLNLNSM-----------VSNINQPLEITAISSPETS-LKSSP 1154
R P +QP P L ++ + PL + +++P S K+ P
Sbjct: 259 ARGTPRAPAHPSQP--KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 1155 VPYQDHDQPPV---LKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLES 1211
VP D+ P+ L PL+ +P + P + PS A S+
Sbjct: 317 VPPPDNAATPLPATLPPSPPLA--TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM-- 372
Query: 1212 KSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSP--ISDIGLAKSADSP-LQASSALS 1268
+PP ++ L P + S ++ SP +S + S SP LQA+ +
Sbjct: 373 TTPP--MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430
Query: 1269 QNSLFTFRPALEEPSADAKLAA-HPRKGFPGSLSGADGLSPGTNPANGCTFGGGLAADLS 1327
S + +L PS A P P SL + L +PA L++ L+
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-----VSPLSSPLT 485
Query: 1328 LHSFSDGASLPHKGPEA 1344
+H +SL P+A
Sbjct: 486 IHPLQALSSLASHSPQA 502
Score = 48.1 bits (113), Expect = 6e-05
Identities = 202/854 (23%), Positives = 285/854 (33%), Gaps = 176/854 (20%)
Query: 727 SRPSSKQNTPQYLASPLDQEVVPCT-PSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHL 785
S P S Q P A+P Q T P P L+ + + P ++ SP+ L
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP-HSLTSPSLQAPPSPL 407
Query: 786 S----QDHTVPGRPAASELHSRAEHT-KENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL 840
+ Q T G P HS + ++ SPS P S +P D PL L L
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS---TPPDSPPLQ-APLSL 463
Query: 841 AGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSI-------PLASVVLPSR 893
+ L P+S PL T+ P + S+ PL+S+++P
Sbjct: 464 PASPPLQTSLSPAVS----------PLSSPL-TIHPLQALSSLASHSPQAPLSSLIMPPL 512
Query: 894 AERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSP 953
++ P P LQ P ++L N L A A + + + +P
Sbjct: 513 ETQSSLAP-PSLQT--PPASLTTPPLENLPSLAPPPLQTASAPLT---TPHLETPPCPAP 566
Query: 954 ASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPR-NSLPASPAHQLSSSP-- 1010
L P T + S+ + PQ P LA P LP+ P L++ P
Sbjct: 567 CPLQAPPSPLTTPPPETPSSI------ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ 620
Query: 1011 -----RLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHS 1065
L P P AS P S + P +A + + S SP + +
Sbjct: 621 APPXLALPPLQAPPSPPAS----PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-A 675
Query: 1066 PLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAG---VSPKRRALPSVAGLFTQPSG 1122
P + A PS S+ PSL+A V P A P ++ T P
Sbjct: 676 PFSPPASPPVSPSATPPSQ----------APPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 1123 SPLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKK---ERPLSQTNGAH 1179
+P L + PL++ SP S SP PP+L + P S
Sbjct: 726 APPPLAA------PPLQVPP--SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Query: 1180 YSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSS 1239
SPL +P + P+ +AT L++ P PA P
Sbjct: 778 MSPLA---KPPPQAPPA-------LATPPLQALPSP---------------PASFP---- 808
Query: 1240 KWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGS 1299
++ FSP + + ++ A P QA L+ L P+ P A L A R PG
Sbjct: 809 -GQAPFSPSASLPMSPLATPPPQAPPVLAA-PLLQVPPS---PPASPTLQAPRRPPTPGP 863
Query: 1300 LSGADG------LSPGTNPANGCTFGGGLAA-DLSLHSFSDGASLPHK------GPEAAG 1346
+ G L+PG P + L+ DL+ HS S S P + GPE
Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS-SSATSTPEELRGYDSGPEGGA 922
Query: 1347 LSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGLPLCGPTDKTPLL 1406
+SP P A +G G G PL P P
Sbjct: 923 AASP--------------PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 968
Query: 1407 SGKAAKARDREVDLKNGHNLFISAAAVPPGSLLSGPGL----APAASSAGGAASSAQTHR 1462
+ + E +A PG+L GP AA+ AG ASS +
Sbjct: 969 ADGLCTIYETEGP---------ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019
Query: 1463 SFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHA 1522
+ LG P G +LQA SV+Q L S A AA
Sbjct: 1020 ARLGELPLG--------ALQA--------SVVQHLLSRTLLLA-------AAEGAAGGSG 1056
Query: 1523 MGSFSGVAGGTVGG 1536
G GG GG
Sbjct: 1057 GGPGGAEGGGVTGG 1070
Score = 48.1 bits (113), Expect = 6e-05
Identities = 180/739 (24%), Positives = 244/739 (33%), Gaps = 134/739 (18%)
Query: 697 TKFSLPHLSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVG 756
T P L + L+M+ + L SRP+S L +PL +P +P
Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQASLTSP-SRPASTPPDSPPLQAPLS---LPASP---- 467
Query: 757 RPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQS 816
P LS +P SP I + LS + + S L T+ + P
Sbjct: 468 -PLQTSLSPAVSP---LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 817 PSVPGSMKLSPQDPRP-LSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLS--T 873
+ P S+ P + P L+P LQ A + L + P+ P S T
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE------TPPCPAPCPLQAPPSPLT 577
Query: 874 VQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALA 933
P + P SI P +A A ++P P P S L A LAL
Sbjct: 578 TPPPETPSSIATP----PPQAPPALASPPLQGLPSPPLSPL-----ATPPPQAPPXLALP 628
Query: 934 P--AGFSYAGSVAISGALAGSPAS---------LTPGAEPATLDESSSSGSLFATVGSRS 982
P A S S +S SP + P + P + + + S S
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
Query: 983 STP--QHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKG-DLPSDSGFSDPES 1039
+TP Q P LA P +P SP SP Q P P A+ +P S P S
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748
Query: 1040 EAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSL 1099
+ +P + PL A+ PS K P+L
Sbjct: 749 PSA----------------TPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 1100 SAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQD 1159
+ +P +ALPS F P +P SP SL SP+
Sbjct: 793 A---TPPLQALPSPPASF--PGQAPF-------------------SPSASLPMSPLATPP 828
Query: 1160 HDQPPVL-------KKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIA--TISLE 1210
PPVL P S T A P T PG + S R+ +A
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT----PGPDTSVSGPRLTLALAPGPPPPP 884
Query: 1211 SKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKS------TFSPISDIGLA--------KS 1256
S+SP TL +G LAG + P + S SP D LA +
Sbjct: 885 SRSPSSTL-SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943
Query: 1257 ADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGC 1316
PL A + + PA SAD + +G + L PG +P
Sbjct: 944 PAPPLAFRGA--PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG--- 998
Query: 1317 TFGGGLAADLSLHSFSDGASLPHKGPEAAGLSS-PLSFPSQRGKEGSDANPFLSKRQL-- 1373
T GG AA GA + P+ A L PL + S LS+ L
Sbjct: 999 TSGGKAAA-------GAGAGASSRSPKQARLGELPLG-----ALQASVVQHLLSRTLLLA 1046
Query: 1374 --DGLAGLKGEGSRGKEAG 1390
+G AG G G G E G
Sbjct: 1047 AAEGAAGGSGGGPGGAEGG 1065
Score = 37.7 bits (86), Expect = 0.086
Identities = 122/506 (24%), Positives = 172/506 (33%), Gaps = 63/506 (12%)
Query: 685 PDASRLHLELDCTKFSLPHLSSMSPELS-MNGQAAGYELCGVLSRPSSKQNTP--QYLAS 741
PD+ L L S P +S+SP +S ++ + L + S S P +
Sbjct: 452 PDSPPLQAPLSLPA-SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP 510
Query: 742 PLDQEV------VPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRP 795
PL+ + + P+ + P LE L LA P S + HL P P
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP--LTTPHLE----TPPCP 564
Query: 796 AASELHSRAEHTKENGLPYQSPSVPGSMKLSP-QDPRPLSPGALQLAGEKSSEKGLRERA 854
A L + + L P P S+ P Q P L+ LQ GL
Sbjct: 565 APCPLQA-----PPSPLTTPPPETPSSIATPPPQAPPALASPPLQ---------GLPSPP 610
Query: 855 YGSSGELITSLPISIPLSTVQ-PNKLPVSIPLASVVLPS-RAERARST----------PS 902
P + L +Q P P S PL+ + PS +A A + PS
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670
Query: 903 PVLQ-PRDPSSTLEKQIGANAHGAGSRSLALAPAGF--SYAGSVAISGALAGSPASLTPG 959
P +Q P P ++ A SLA P S S +S + P + P
Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730
Query: 960 AEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGP 1019
A P L S + S + P+ P LLA P +P SP L SP Q P
Sbjct: 731 AAPP-LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789
Query: 1020 LPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAG-SAKQSPSSKHSPLTASARGDCVPS 1078
A+ P P + + F+ + S +P + P+ A+ PS
Sbjct: 790 PALAT----PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845
Query: 1079 HGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNS-------MV 1131
+ R+ TP VS R L G PS SP + S
Sbjct: 846 PPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 1132 SNINQPLEITAI-SSPETSLKSSPVP 1156
S + P E+ S PE +SP P
Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPP 928
Score = 36.6 bits (83), Expect = 0.19
Identities = 81/340 (23%), Positives = 120/340 (35%), Gaps = 51/340 (15%)
Query: 1184 TSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKS 1243
TS P S P+S R ER ++ SP G +P P G+ +
Sbjct: 85 TSSRNPASRP-PASGRGERAPPA---KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 140
Query: 1244 TFSPISDIGLAKSADSPLQAS-SALSQNSLFTFRPALEEPS-ADAKLAAHPRKGFPGSLS 1301
T + K+ ++P +++ SA ++ P P+ A AA G P
Sbjct: 141 T------VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194
Query: 1302 GADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAG--------------- 1346
A P P + S HS ++ + + P A G
Sbjct: 195 SARPRPPTEGPRKS-------VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 1347 -LSSPL-SFPSQRGKEGSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGLPLCGPTDKTP 1404
LSSP S PS RG + A+P S+ + GL L+ + + P GP +P
Sbjct: 248 PLSSPARSGPSARGTPRAPAHP--SQPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSP 303
Query: 1405 LLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLSGPGLA---PAASSAGGAASSAQTH 1461
L + + + R V + +AA P +L P LA P A + A S QT
Sbjct: 304 LATPSPSGTKARPVPPPD------NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
Query: 1462 RS--FLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFS 1499
S P P PM +L ++ V SL S
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397
Score = 36.2 bits (82), Expect = 0.25
Identities = 47/196 (23%), Positives = 70/196 (35%), Gaps = 13/196 (6%)
Query: 332 PKLREEQEAARRRQQRESKSNAAT--PTKGPEGKVAGPADAPMDSGAEEEKAGAATVKKP 389
P R A Q + K A P P K A PA P+ S + + P
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS---------SPLATP 307
Query: 390 SPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAASSP 449
SPS + + + P A P + +A +L QT+ A+ P
Sbjct: 308 SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL--QTLPSPPATPP 365
Query: 450 QDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKA 509
A S +P Q PPS+Q P + + T P+LQ + LQ +P +A
Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425
Query: 510 SLQELLGQEKEKNAQL 525
+ L ++ A L
Sbjct: 426 THSFLTMSPRQTQASL 441
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 59.7 bits (143), Expect = 2e-08
Identities = 189/848 (22%), Positives = 276/848 (32%), Gaps = 143/848 (16%)
Query: 729 PSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQD 788
PS K A+P + P TPS G P ++ P + SPA + S
Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT----PPSPKGSPAATPFPKGASTP 1035
Query: 789 HTVP-----GRPAASELHSRAEHTKE---------------NGLPYQSPSVPGSMKLSPQ 828
G PAA+ L A T G P + P S K P
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095
Query: 829 DPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIP--LSTVQPNKLPVS---- 882
P P A S + GL + + + P S L+T P P +
Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155
Query: 883 ---------------IPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANA----H 923
P P + +TPSP P P++T G A
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 924 GAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAE--PATLDESSSSGSLFATVGSR 981
GA + A P+ + + GA +PA+ P + PAT + AT S
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPT-TPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274
Query: 982 S---STPQHPLLLAQPRNSLPASPAHQLSSSPRLGG----AAQGPLPEASKGDLPSDSGF 1034
+TP H P P SP ++SP G AA P P+ S G P G
Sbjct: 1275 KGGLATPPHKGA-PNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT-PPPKGA 1332
Query: 1035 SDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASA 1094
P + T T A +PSSK P T S++ P S + G A
Sbjct: 1333 PTPPAVTPPSPKGTPTLPA----TTPSSKGGPTTPSSKEGPTPPAATPSHKGG-----PA 1383
Query: 1095 GTPSLSAGVSPKR-RALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSS 1153
TP SPKR A+PS G T P+ PL+ + P+ ++P +
Sbjct: 1384 MTPP-----SPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT---PVTREGAATPSKGDLTP 1435
Query: 1154 PVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDE------EPGSEDEPSSARIERKIATI 1207
P P LKK S G +P + + P S EP + +++AT
Sbjct: 1436 PAV-----TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA---PKQVATS 1487
Query: 1208 SLESKSPPKTLENGGGL--AGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASS 1265
S K+P G A +P P S + +P + + L+K + L
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL-LSKKTPATLAPKE 1546
Query: 1266 ALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGGGLAAD 1325
AL PA+ PS A K P + S + SP T+ G +
Sbjct: 1547 AL-------IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA--VTPSTYKGAPSPK 1597
Query: 1326 LSLHSFSDGASLPHKGPEAAGLS--SPLSFPSQRGKEGSDANPFLSKRQLDG-------- 1375
L + + P + P ++ SP P+ +G+ +P ++ L
Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASV 1657
Query: 1376 ---LAGLKGEGSRGKEAGEGGLPL-----CGPTDKTPLLSGKAAKARDR----------- 1416
+ + S+G A +G L + TP+++ K
Sbjct: 1658 TCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC 1717
Query: 1417 -EVDLKNGHNLFISAAAVPPGSLLSGPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFA 1475
+ KNG +S A P L P + A S GP P A
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAP--------LLPVQKDSSKTAKGKDASHSPKGPLAPPESKA 1769
Query: 1476 LGPMSLQA 1483
P++ A
Sbjct: 1770 STPLTAAA 1777
Score = 56.6 bits (135), Expect = 2e-07
Identities = 109/487 (22%), Positives = 175/487 (35%), Gaps = 49/487 (10%)
Query: 729 PSSKQN-TPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQ 787
PS K+ P+ +A+ + P TP+ +G P L + P + PA RR
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV----IPSSPKEVPATPSSRRD--- 1525
Query: 788 DHTVPGRPAASELHSRAEHT---KENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEK 844
P P A+ L + T KE +P + +VP S K +P P P A + E
Sbjct: 1526 ----PIAPTATLLSKKTPATLAPKEALIP-PAMTVP-SPKKTPAIPTPKEAPATPSSKEA 1579
Query: 845 SSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPV 904
SS + Y + + + IP + P+ P P V P E+ +TP+P
Sbjct: 1580 SSPPAVTPSTYKGAP---SPKELLIPPAVTSPS--PKEAPTPPAVTPPSPEKGPATPAPK 1634
Query: 905 LQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPAT 964
P P T + + +PA + + A G PA P A
Sbjct: 1635 GTPTSPPVT----------PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684
Query: 965 LDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEAS 1024
L + + T +R Q + S SP + P ++GPL +
Sbjct: 1685 LVAPAPESTPIITAPTRKGP--------QTKKSSATSPP--ICPDPSAKNGSKGPLSTVA 1734
Query: 1025 KGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSR 1084
L D AK + G + +S +S +PLTA+A +P S
Sbjct: 1735 PAPLLPVQ--KDSSKTAKGKDASHSPKGPLAPPESKAS--TPLTAAAFEKVLPKPESASV 1790
Query: 1085 RRGRRKRASAG-TPSLSAGVSPKRRALPSVAGLFTQPSGSPLNL--NSMVSNINQPLEIT 1141
S PS + PK++ LPS GL + PL + + P I+
Sbjct: 1791 SAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS 1850
Query: 1142 AISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIE 1201
++ L + P P P ++P+++ N + SDE +E S +
Sbjct: 1851 GGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQAT 1910
Query: 1202 RKIATIS 1208
+ A ++
Sbjct: 1911 TQQAQLA 1917
Score = 52.0 bits (123), Expect = 4e-06
Identities = 126/517 (24%), Positives = 180/517 (34%), Gaps = 93/517 (17%)
Query: 862 ITSLPISIPLST----VQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQ 917
+T+LP+ +P ++ V P+ PLA++VL E +S PSP L P +K
Sbjct: 695 LTTLPL-VPTASENCPVAPSPQNTCAPLATLVLAP--EIPKSVPSPSLPPAGTPPGTKKV 751
Query: 918 IGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFAT 977
G S + ALAP +A SP P + +SS G+L
Sbjct: 752 DGI------SHTSALAP--------------VASSPKEC-PTEDSGASATASSKGTL--- 787
Query: 978 VGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDP 1037
LA + L S + Q P G+A P+ G+L S P
Sbjct: 788 -----------TYLADSPSPLGVSVSPQTKRPPTKKGSAG---PDTPIGNL------SSP 827
Query: 1038 ESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTP 1097
S + + + +K SP++ HSP S +G P SA TP
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP---------------SAVTP 872
Query: 1098 SLSAGVS--PKRRALPSVAGLFTQPSG----SPLNLNSMVSNINQPLEITAISSPETSLK 1151
GV+ PK PSV L G +P ++ + P + A +P+ +
Sbjct: 873 LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK-GIP 931
Query: 1152 SSPVPYQDHDQPPVLKKERPLS--QTNGAHYSP----LTSDEEPGSEDEPSSARIERKIA 1205
+SP P + PP P T ++P T G PS A
Sbjct: 932 ASPSP-KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990
Query: 1206 TISLESKSPPKTLENGGG---LAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQ 1262
K P T G A P+P G P + K +P A + SP
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP-----PAATPPSPKG 1045
Query: 1263 ASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGGGL 1322
+ +A PA PS A KG P + A SP PA G +
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP-TPPAATPPSPKGGPATPSPKGAPM 1104
Query: 1323 AADLSLHSFSDG-ASLPHKGPEAAGLSSPLSFPSQRG 1358
+ S G A+ PHKG ++P PS +G
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATP---PSPKG 1138
Score = 50.1 bits (118), Expect = 2e-05
Identities = 196/842 (23%), Positives = 269/842 (31%), Gaps = 188/842 (22%)
Query: 701 LPHLSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLA---SPLDQEVVPCTPSHVGR 757
+ H S+++P S + + E G + SSK T YLA SPL V P T R
Sbjct: 754 ISHTSALAPVAS-SPKECPTEDSGASATASSK-GTLTYLADSPSPLGVSVSPQTK----R 807
Query: 758 PRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSP 817
P +K G A PD T G ++ A EN L +Q
Sbjct: 808 PPTKK--GSAGPD-------------------TPIGNLSSPVSPVEASFLPENSLSFQGS 846
Query: 818 SVPGSMKLSPQDPRP-----------LSPGALQLAGEKSSEKGLRERAYGSSGELITSLP 866
+ SP P P LSP + L +++ + + G T P
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA-TPAP 905
Query: 867 ISIPL------------STVQPNKLPVS-----IPLASVVLPSRAERARSTPSPVLQPRD 909
P +T P +P S P P + +TPSP P
Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
Query: 910 PSSTLEKQIGANA----HGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATL 965
P++T G A GA + A P+ G PA+ +P P
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSP-------------KGGPATPSPKGAPTPP 1012
Query: 966 DESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASK 1025
+ S GS ++TP P + P + P SP +++P GA P
Sbjct: 1013 AVTPPSPK-----GSPAATP-FPKGASTPPAATPPSPKGSPAATPLPKGA-----PTTPA 1061
Query: 1026 GDLPSDSGFSDPESEAKRRIVFTITTGAGS--AKQSPSSKHSPLTASARGDCVPSHGQD- 1082
LPS G P + + + GA + A PS K P T S +G +P
Sbjct: 1062 ATLPSPKG--GPATPSLK--------GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Query: 1083 SRRRGRRKRASAGTPSLSAGVSPKRR---ALPSVAGLFTQPSGSPLNLNSMVSNINQPLE 1139
S + G G P+ A P + A P G T P+ +P
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP--------------- 1156
Query: 1140 ITAISSPETSLKSSP---VPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEP-GSEDEP 1195
SP+ L + P P PP K GA +P + P G P
Sbjct: 1157 ----PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Query: 1196 SSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAK 1255
S + T + PK GGLA P+P G P + + K
Sbjct: 1213 SP----KGAPTTPAATPPSPK-----GGLA--TPSPKGAPTTPAATPPSPKGGPATPPPK 1261
Query: 1256 SADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGS---LSGADGLSPGTNP 1312
A +P PA PS LA P KG P + P T+P
Sbjct: 1262 GAPTP----------------PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305
Query: 1313 ANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSS---------PLSFPSQRG----- 1358
G AA S G P P ++ P + PS +G
Sbjct: 1306 PKGAPTPP--AATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 1359 --KEGSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGLPLCGPTDKTPL-LSGKAAKA-- 1413
KEG P + G A RG P PT + LS K A A
Sbjct: 1364 SSKEG-PTPPAATPSHKGGPAMTPPSPKRGPAIPS---PKGDPTSPAVIPLSPKKAPATP 1419
Query: 1414 --RDREVDLKNGHNLFISAAAVPPGSLLSGPGLAPAASSAGGAASSAQTHRSFLGPFPPG 1471
R+ G ++ AV P SL P A +A G A S++ + PP
Sbjct: 1420 VTREGAATPSKGD---LTPPAVTPVSLKKAP--ATSAPKGGPATPSSKGDPTLPAVTPPS 1474
Query: 1472 PQ 1473
P+
Sbjct: 1475 PK 1476
Score = 47.0 bits (110), Expect = 1e-04
Identities = 195/865 (22%), Positives = 297/865 (34%), Gaps = 135/865 (15%)
Query: 697 TKFSLPHLSSMSPELSMNGQAAGYELCGVLSRP-SSKQNTPQYLASPLDQEVVPCTPSHV 755
T FSL +S+ + S N A Y V P SS TP + +P P T V
Sbjct: 403 TSFSLSPTTSLILKSSPN---ATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEV 459
Query: 756 GRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQ 815
+S + SPA +V+ ++ P A+ L +P
Sbjct: 460 ATCVSPPMSSGPISNIEPTSPAALVMAPVAPKE---PSTQVATTLR----------IPV- 505
Query: 816 SPSVPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQ 875
SP +P P+D + L L + ++K L+ G P S + +
Sbjct: 506 SPPLP-----DPEDLKNLPSSVLV---KFPTQKDLQTVPASLEGA-----PFSPAQAGLT 552
Query: 876 PNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTL-EKQIGANAHGAGSRSLALAP 934
K P +PL P + +ST S P P +TL +K +G S +P
Sbjct: 553 TKKDPTVLPLVQAA-PKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSP 611
Query: 935 AGFSYAGSVAISGALAGSPAS--------LTP--------GAEPATLDESSSSGSLFATV 978
G + + SV + + AG ++ +TP A+PA + +++ G+ T
Sbjct: 612 LGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTT 671
Query: 979 -------GSRSSTPQ-HPL---------LLAQPRNSLPASPAHQLSSSPRLGGAAQGPLP 1021
G+ S P+ HP+ L+ + P +P+ Q + +P +P
Sbjct: 672 TASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIP 731
Query: 1022 EASKGDLPSDSGFSDPESEAKRRIVFT--ITTGAGSAKQSPS-SKHSPLTASARGDCV-- 1076
++ +G + P ++ I T + A S K+ P+ + TAS++G
Sbjct: 732 KSVPSPSLPPAG-TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL 790
Query: 1077 ---PS----HGQDSRRRGRRKRASAG--TP--SLSAGVSPKRRA-LPSVAGLFTQPSGSP 1124
PS +R K+ SAG TP +LS+ VSP + LP + F SP
Sbjct: 791 ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP 850
Query: 1125 LNLNSMV----SNINQPLEITAIS----------SPETSLKSSPVPYQDHDQPPVLKKER 1170
+S P +T +S +P S+ + P P ++ P K+
Sbjct: 851 ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP-KEGPATPAPKQAP 909
Query: 1171 PLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGG---LAGR 1227
LS T+ + + G PS A K P T A
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 1228 KPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPSADAK 1287
P+P G P S + P A + SP + S T PA+ PS
Sbjct: 970 PPSPKGGPATPSPKGAPTPP------AATPPSPKGGPATPSPKGAPT-PPAVTPPSPKGS 1022
Query: 1288 LAAHPRKGFPGSLSGADGLSP----GTNPANGCTFGGGLAADLSLHSFSDGASLPH-KG- 1341
AA P FP S +P G+ A G +L S G + P KG
Sbjct: 1023 PAATP---FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 1342 --PEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGLPLCGP 1399
P AA SP P+ +G+ P + G GL +G P P
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG--GLATPPHKGAPTTPAATP---P 1134
Query: 1400 TDK----TPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLSGPGLAPAASSAGGAA 1455
+ K TP G K G A PP + P P + G A
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPKGG------LATPPPKGAPTTPAATPPSPKGGLAT 1188
Query: 1456 SSAQTHRSFLGPFPPGPQFALGPMS 1480
S + + PP P+ L S
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPS 1213
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 58.2 bits (139), Expect = 6e-08
Identities = 118/531 (22%), Positives = 189/531 (35%), Gaps = 51/531 (9%)
Query: 825 LSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIP 884
+ P P+P + L G + ++ + +G T +S + N P S P
Sbjct: 1197 MPPTTPQPPTTPQLPTTGSRPTQ------VWPMTGTSTTIGLLSSTGPSPSSNHTPAS-P 1249
Query: 885 LASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVA 944
+ +LP+ ++ T S PR ++ + A RS A P
Sbjct: 1250 TQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT--------- 1300
Query: 945 ISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAH 1004
++ A + AS A PAT + S+ T+ + +++ P L LP + A
Sbjct: 1301 VTQATTRATAST---ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTAT 1357
Query: 1005 QLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKH 1064
Q ++ PR P P ++ G G P T TT + Q+P + H
Sbjct: 1358 Q-TTGPR-------PTPASTTGPTTPQPG--QPTRPTATETTQTRTTTEYTTPQTPHTTH 1407
Query: 1065 SPLTASARGDCVPSHGQDSRRRGRRKRASAGTPS-----LSAGVSPKRRAL--PSVAGLF 1117
SP TA G VPS G + + TPS L V P +L PS +
Sbjct: 1408 SPPTA---GSPVPSTGPVT-ATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVI 1463
Query: 1118 T----QPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPV---PYQDHDQPPVLKKER 1170
T Q + S N ++ I P + A S T+ +P Q H K
Sbjct: 1464 TPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPT 1523
Query: 1171 PL-SQTNGAHYSPLTSDEEPGSEDEPSSARIERKIA-TISLESKSPPKTLENGGGLAGRK 1228
L S T+ H+ +T P+S R +A T S S PP G
Sbjct: 1524 SLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS 1583
Query: 1229 PAPAGEPVNSSKWK--STFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPSADA 1286
P + P+ ++ +K +T+ S P ++S ++ ++ P + + A
Sbjct: 1584 PFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSA 1643
Query: 1287 KLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASL 1337
+ + P P + S T P T G A SL++ SL
Sbjct: 1644 SIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSL 1694
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 57.4 bits (137), Expect = 1e-07
Identities = 147/615 (23%), Positives = 213/615 (34%), Gaps = 129/615 (20%)
Query: 786 SQDHTVPGRPAASELHS--RAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGE 843
S D + P A+ HS R N S P SM +P D R SPG L+ G
Sbjct: 2084 SSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRP-SMSPTPLD-RCRSPGMLEPLGS 2141
Query: 844 KSSEKGLRERAYGSS----GELI-----TSLP------------ISIPLSTVQP------ 876
+ + ++A GS G I TS+P +I L T +P
Sbjct: 2142 SRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA 2201
Query: 877 -------NKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRS 929
+++P +PL S+ A A P+ + +S I + A SR+
Sbjct: 2202 AGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRT 2261
Query: 930 LALAPAGFSYAGSVAISGALAGSPASLTPGAE---------PATLDESSSSGS----LFA 976
A A A + A++ + TP A PA L S +GS A
Sbjct: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA 2321
Query: 977 TVGSRSSTPQHPLL--LAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGF 1034
S S TPQ P L PR++ +P + ++ S A L A S +
Sbjct: 2322 NYPSSSRTPQAPASANLVGPRSAHATAPVN-IAGSRTAAALAPASLTSARMAPALSGANL 2380
Query: 1035 SDPE--SEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRA 1092
+ P A R+ S + SP PL AR PS SR R
Sbjct: 2381 TSPRVPLSAYERV---------SGRTSP-----PLLDRARSRTPPSAPSQSRMTSER--- 2423
Query: 1093 SAGTPSLSAGVSPKRRALP--------------------------SVAGLFTQPSGSPLN 1126
A +PS G +P + LP VAG + SG+
Sbjct: 2424 -APSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVAT 2482
Query: 1127 LNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPL-------------- 1172
S + N L + A P + + P QP L +P
Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPAS-TGAQQPSALAALQPAKERRSSSSSSSSSS 2541
Query: 1173 -SQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSP-PKTLENGGGLAGRKPA 1230
S ++ + S +S S+ E SS ++ ++A + S +P PK GR P
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR----EGRPPE 2597
Query: 1231 PA-------GEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPS 1283
P +SS S+ S S + S+ S +SS+ S +S + PA P
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657
Query: 1284 ADAKLAAHPRKGFPG 1298
A K A P+K PG
Sbjct: 2658 ALPK-PASPKKPPPG 2671
Score = 50.1 bits (118), Expect = 2e-05
Identities = 108/454 (23%), Positives = 167/454 (36%), Gaps = 64/454 (14%)
Query: 894 AERARSTPSPVLQPRDPSSTLEKQIGAN-----AHGAGSRSLALAPAGFSYAGSVAISGA 948
A R T SPV + R S + ++ G + A SRS A G S + + A
Sbjct: 621 ARRRSRTRSPVRR-RSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPA---R 676
Query: 949 LAGSPASLTPGAEPATLDES-----SSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPA 1003
+G S TP + + S S SL S S TPQ + R+ +
Sbjct: 677 RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR-----RGRSGSSSERK 731
Query: 1004 HQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSK 1063
++ +S R + P + S+ S P S+AK R+ + +GS+
Sbjct: 732 NKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSL-SGSSPCPKQKS 790
Query: 1064 HSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGS 1123
+P S G P SR RR R+S+ P +P R++ S + SG+
Sbjct: 791 QTPPRRSRSGSSQPK--AKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT 848
Query: 1124 PLNLNSMVSNINQPLEITA------ISSPETSLKS-SPVPYQ-DHDQPPVLKKERPLSQT 1175
P S+ S +T SSP+ LKS +P + PP +K P Q+
Sbjct: 849 PPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908
Query: 1176 NGAHYSPL----------------TSDEEPGSEDEPSSARIERKIATIS-LESKSPPKTL 1218
SP +S P ++ R R ++ S +ES+ P+
Sbjct: 909 PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYS 968
Query: 1219 ENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPA 1278
+G K P P S + SP + A +P S + S++ P
Sbjct: 969 HSGSSSPDTKVKPETPPRQSH--SGSISPYPKV----KAQTPPGPSLSGSKS------PC 1016
Query: 1279 LEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNP 1312
+E S D+ + + PGSLS G+ T P
Sbjct: 1017 PQEKSKDSLV-----QSCPGSLSLCAGVKSSTPP 1045
Score = 48.1 bits (113), Expect = 6e-05
Identities = 115/459 (25%), Positives = 169/459 (36%), Gaps = 64/459 (13%)
Query: 677 GALGRELEPDASRLHLELDCTKFSLPHLSSMSPE------LSMNGQAAGYELCGVLSRPS 730
G +LE D S L ++ T+ S S +SP+ +S N + L V PS
Sbjct: 1357 GPFLNQLETDPS-LDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPS 1415
Query: 731 SKQNTPQYLASPLDQEVVPCTPSHVGR----PRLEKLSGLAAPDYTRLSPAKIVLRRHLS 786
++++ +SP ++ +P TPS R P L SG +P++ L
Sbjct: 1416 RERSSSA--SSPEMKDGLPRTPSRRSRSGSSPGLRDGSG---------TPSRHSLSGSSP 1464
Query: 787 QDHTVPGRPAA--SELHSRAEHTKENGLPY---QSPSVP--GSMKLSPQDPRPLSPGALQ 839
+P P+ SE S E P +SPS P + L+PQ R S ++
Sbjct: 1465 GMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVD 1524
Query: 840 LAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARS 899
+ G R R+ GSS EL P + P + + P S A P R +R+RS
Sbjct: 1525 QKTVARTPLGQRSRS-GSSQELDVK-PSASPQERSESDSSPDS--KAKTRTPLR-QRSRS 1579
Query: 900 TPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPG 959
SP + + S + G++ A A +GS +S P
Sbjct: 1580 GSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA--------------PRAQSGSDSSPEPK 1625
Query: 960 AE-PATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQG 1018
A P L S SGS S+ P + +S +SP H S G+
Sbjct: 1626 APAPRALPRRSRSGS-----SSKGRGPS-----PEGSSSTESSPEHPPKSRTARRGSRSS 1675
Query: 1019 PLPEASKGDLPSD-SGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVP 1077
P P+ P S S PE K R+ + + SA SP ++ R V
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARL----SRRSRSASSSPETRSRTPPRHRRSPSVS 1731
Query: 1078 SHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGL 1116
S + R R+R SA +P R P GL
Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGL 1770
Score = 47.0 bits (110), Expect = 1e-04
Identities = 204/1000 (20%), Positives = 337/1000 (33%), Gaps = 160/1000 (16%)
Query: 328 SLKNPKLREEQEAARRRQQRESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVK 387
S+ +P+ E+ +RR ES + ++ P + P + + +
Sbjct: 854 SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSS 913
Query: 388 KPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTA--LDALHAQTVSQTA 445
P P K ++ + R +G P ++ + R+ + +++ S +
Sbjct: 914 SPQPKV--KAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSG 971
Query: 446 ASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTP 505
+SSP + P S+ SP P + A TPP L+ +K+P
Sbjct: 972 SSSPDTKVKPETPPRQSHSGSI---SPYPKVKAQTPPGPS-------------LSGSKSP 1015
Query: 506 QYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLI 565
QEK K++ L+ + LS C K GV +L
Sbjct: 1016 ---------CPQEKSKDS-LVQSCPGSLSLCAGVKSST----PPGESYFGVSSLQLKGQS 1061
Query: 566 QAQ------------KEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWAT 613
Q ++ + + L+ +S+ + R+ + L +R ++ D
Sbjct: 1062 QTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASR-SPIRQDRGE 1120
Query: 614 LSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPP-DDALSLH 672
S +LK + + + S L +S+ + + K +PP +DA +
Sbjct: 1121 FSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASP 1180
Query: 673 LRGKGALGRELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGYELCGVLSRPSSK 732
R K D L T + P E G S P +K
Sbjct: 1181 PRQKDKFSPFPVQDRPESSLVFKDTLRTPPR-----------------ERSGAGSSPETK 1223
Query: 733 QNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVP 792
+ S D+E++ P + LS L+ S K + + V
Sbjct: 1224 EQNSALPTSSQDEELMEVVEKSE-EPAGQILSHLS-------SELKEMSTSNFESSPEVE 1275
Query: 793 GRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRE 852
RPA S +++ ++ VP SM S P SP +L S LRE
Sbjct: 1276 ERPAVSLTLDQSQSQAS----LEAVEVP-SMASSWGGPH-FSPEHKEL-----SNSPLRE 1324
Query: 853 RAYGSSGELITSLPISIPLST-------------------------VQPNKLPVSIPLAS 887
++GS E S P+ ++T ++ S +S
Sbjct: 1325 NSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS 1384
Query: 888 VVLPSRAERA-----RSTPSPVLQ--PRDPSSTLEKQIGANAHGAG------SRSLALAP 934
+ P E+A +S SPVL PR PS + G RS + +
Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSS 1444
Query: 935 AGFSYAGSVAISGALAGSPASL-----TPGAEPATLDESSSSGSLFATVGSRSSTPQHP- 988
G +L+GS + TP + D S +L T RS +P P
Sbjct: 1445 PGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504
Query: 989 ----LLLAQPRNSLPASPAHQ-------LSSSPRLGGAAQGPLPEASKGDLPSDSGFSDP 1037
L Q S S Q L R G + + + ++ S+S S P
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESD-SSP 1563
Query: 1038 ESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTP 1097
+S+AK R + +GS+ + S S G S + + RA +G+
Sbjct: 1564 DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSG----SSPEVKDKPRAAPRAQSGSD 1619
Query: 1098 SLSAGVSPKRRALP--SVAGLFTQPSG-SPLNLNSMVSNINQPLEITAI-----SSPETS 1149
S +P RALP S +G ++ G SP +S S+ P + SSPE
Sbjct: 1620 SSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPK 1679
Query: 1150 LKSSPVPYQ--DHDQPPVLKKERPLSQTNGAHYSPLTSDEEP----GSEDEPSSARIERK 1203
KS P + P + +K R ++ A SP T P S S E+
Sbjct: 1680 TKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKS 1739
Query: 1204 IATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKS 1243
++ S S P+T GR P+P + S+ +S
Sbjct: 1740 RSSRRRRSASSPRTKTT--SRRGRSPSPKPRGLQRSRSRS 1777
Score = 44.3 bits (103), Expect = 0.001
Identities = 112/518 (21%), Positives = 182/518 (35%), Gaps = 76/518 (14%)
Query: 726 LSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHL 785
LS P SK + L L PC P SG + P +P +
Sbjct: 762 LSSPRSKAKSRLSLRRSLSGSS-PCPKQKSQTPPRRSRSGSSQPKAKSRTPPR------R 814
Query: 786 SQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVP---GSMKLSPQDPRPLSPGALQLAG 842
S+ + P S+ SR H+ + P P GS+ + + ++P +
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR-RSCF 873
Query: 843 EKSSEKGLRERA---YGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLP-SRAERAR 898
E S + L+ R + SG + S P + +++ P R+
Sbjct: 874 ESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS 933
Query: 899 STPSPV-----LQPR-----DPSSTLEKQIGANAHGAGSRSLAL-----APAGFSYAGSV 943
S+PSP PR P S +E ++ +GS S P S++GS+
Sbjct: 934 SSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSI 993
Query: 944 AISGALAGS--PASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPAS 1001
+ + P G++ E S + + GS S L A ++S P
Sbjct: 994 SPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLS-------LCAGVKSSTPPG 1046
Query: 1002 PAHQLSSSPRLGGAAQGPLPEASKGDLPS--DSGFSDPESEAKRRIVFTITTGAGSAKQS 1059
++ SS +L G +Q S P S P ++K + S K
Sbjct: 1047 ESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQT---------SPKGG 1097
Query: 1060 PSSKHSPLTASARGDCVPSHGQDSRRRGRRKRAS-AGTPSLSAGVSPKRRALPSVAGLFT 1118
S SP+T A SR R+ R + +P L +G+SP++ S + +
Sbjct: 1098 RSRSSSPVTELA-----------SRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYP 1146
Query: 1119 QPSGSPLNLNSMVSNINQ-------PLEITAISSPETSLKSSPVPYQDHDQPPVLKKE-- 1169
+ L S + P E S P K SP P QD + ++ K+
Sbjct: 1147 TVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTL 1206
Query: 1170 -RPLSQTNGAHYSPLTSDEE----PGSEDEPSSARIER 1202
P + +GA SP T ++ S+DE +E+
Sbjct: 1207 RTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEK 1244
Score = 42.4 bits (98), Expect = 0.004
Identities = 124/551 (22%), Positives = 199/551 (36%), Gaps = 100/551 (18%)
Query: 775 SPAKIVLRRHLSQDHTVPGRP---AASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPR 831
S ++ ++RR S T R ++SE +++ ++ SP + S ++S + R
Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKS-RISSRRSR 760
Query: 832 PLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQP--NKLPVSIPLASVV 889
LS + S LR GSS P S P ++ S P A
Sbjct: 761 SLSSPR----SKAKSRLSLRRSLSGSS-------PCPKQKSQTPPRRSRSGSSQPKAKSR 809
Query: 890 LPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGAL 949
P R R+ S+P P + + PS +H + S P +G+ G++
Sbjct: 810 TPPRRSRSSSSPPPKQKSKTPSR--------QSHSSSS------PHPKVKSGTPPRQGSI 855
Query: 950 AGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSS 1009
A+ +S TPQ R+ +SP +L S
Sbjct: 856 TSPQAN------------------------EQSVTPQR-------RSCFESSPDPELKSR 884
Query: 1010 PRLGGAAQGPLPEASKGDLP---SDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSP 1066
+ G P K P S S S P+ + K I + +GS+ SPS S
Sbjct: 885 TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR 944
Query: 1067 LTASARGDCVPSHGQDSRRRGRRKRASAGTP------------SLSAGVSPKRRAL---- 1110
T P +SR R + + +P S S +SP +
Sbjct: 945 TTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP 1004
Query: 1111 --PSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKK 1168
PS++G P + +S+V + L + A +KSS P + + L+
Sbjct: 1005 PGPSLSG-SKSPCPQEKSKDSLVQSCPGSLSLCA------GVKSSTPPGESYFGVSSLQL 1057
Query: 1169 ERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRK 1228
+ SQT+ H S +S E S E S + + + + S+S E LA R
Sbjct: 1058 -KGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTE----LASRS 1112
Query: 1229 P--APAGEPVNSSKWKSTFSPISDIGLAKSADSP-LQASSALSQNSLFT--FRPALEEPS 1283
P GE S KS SP + S+ P + ++S L Q+ L T + + P
Sbjct: 1113 PIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPP 1172
Query: 1284 ADAKLAAHPRK 1294
+ A+ PR+
Sbjct: 1173 QEDATASPPRQ 1183
Score = 38.1 bits (87), Expect = 0.066
Identities = 80/364 (21%), Positives = 133/364 (36%), Gaps = 28/364 (7%)
Query: 703 HLSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEK 762
+L+S LS + +G +L R S+ S + E P S +G+ +
Sbjct: 2379 NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS 2438
Query: 763 LSGLAAPD--------YTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPY 814
L A ++ S I ++ ++ A+ S +H +P
Sbjct: 2439 LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP- 2497
Query: 815 QSPSVP----GSMKLSPQDPRPLSPGALQLAGEK---SSEKGLRERAYGSSGELITSLPI 867
+P VP G S +P + ALQ A E+ SS + SS +S
Sbjct: 2498 -APGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556
Query: 868 SIPLSTVQPNKLPVSIPLASVVLPS------RAERARSTPSPVLQPRDP-SSTLEKQIGA 920
S + + LPV +A +PS A R P P R SS+ +
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
Query: 921 NAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGS 980
++ + S S + + + S + S + S + + SP+ PG P L + +S
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG--PQALPKPASPKKP-PPGER 2673
Query: 981 RSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESE 1040
RS +P+ P+ + SL SP + SP+ Q + +G G S S
Sbjct: 2674 RSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ-QSSSSERGSRRGQRGDSRSPSH 2732
Query: 1041 AKRR 1044
+RR
Sbjct: 2733 KRRR 2736
Score = 37.0 bits (84), Expect = 0.15
Identities = 66/287 (22%), Positives = 94/287 (32%), Gaps = 28/287 (9%)
Query: 845 SSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERA-RSTPSP 903
S +G + + G T P S +T QP S P + + A R +PSP
Sbjct: 300 SGRRGEGDAPFSEPGTTSTQRPSSPETATKQP-----SSPYEDKDKDKKEKSATRPSPSP 354
Query: 904 VLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPA 963
P + A HG + LA P + + +P P
Sbjct: 355 ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414
Query: 964 TLDESSSSGSLFATVGSR--SSTPQHPLLLAQP--RNSLPASP--------------AHQ 1005
+ SS S T SR SS+P+ P P + +SP +H
Sbjct: 415 SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474
Query: 1006 LSSSPRLGGAAQGPLPE--ASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSK 1063
+ S R+G + + S+ P+ G S S RR G + Q
Sbjct: 475 HTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRS 534
Query: 1064 HSPLTAS-ARGDCVPSHGQD-SRRRGRRKRASAGTPSLSAGVSPKRR 1108
SP +R G+ S RRGR S T S +P RR
Sbjct: 535 RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARR 581
Score = 34.7 bits (78), Expect = 0.73
Identities = 63/271 (23%), Positives = 98/271 (36%), Gaps = 30/271 (11%)
Query: 999 PASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGF-SDPESEAKRRIVFTITTGAGSAK 1057
PA + S R +++ P P+ K D G S+ S + R + S
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 1058 QSPSSKHSPLTASARGDCVPSHGQDSRR-----RGRRKRASAGTPSLSAGVSPKRRALPS 1112
+S KH T ++ + SR + RR S S S+ + + R+ +
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
Query: 1113 VAGLFT------QPSGSPLNLNSMVSNINQP--LEITAISSPETSLKSSPVPYQDHDQPP 1164
A T PS + + ++P SSPET+ K PY+D D+
Sbjct: 283 AAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKD- 341
Query: 1165 VLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIER------KIATISLESKSPPKTL 1218
KKE+ ++ + + T E P P+ ER +AT L S+ P
Sbjct: 342 --KKEKSATRPSPSPERSSTGPEPPA----PTPLLAERHGGSPQPLATTPL-SQEPVNPP 394
Query: 1219 ENGGGLAGRKP--APAGEPVNSSKWKSTFSP 1247
R P +P P +SS S SP
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
Score = 33.5 bits (75), Expect = 1.6
Identities = 34/146 (23%), Positives = 59/146 (40%), Gaps = 15/146 (10%)
Query: 343 RRQQRESKSNAATPTKGPEGKV----AGPADAPMDSGAEEEKAGAATVKKPSPSKARKKK 398
+R+ RE+K A P K P V + + P +++K + SP + RKK
Sbjct: 154 QRRAREAKQPAPEPPK-PYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS 212
Query: 399 LNKKGRKMAGRKRGRPKKMNTANPERKP-----KKNQTALDA-----LHAQTVSQTAASS 448
KK + + R + T +RK K++++ A H T + +A+SS
Sbjct: 213 SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS 272
Query: 449 PQDAYRSPHSPFYQLPPSVQRHSPNP 474
RS + ++ SP+P
Sbjct: 273 DTSRSRSRSAAAKTHTTALAGRSPSP 298
Score = 33.5 bits (75), Expect = 1.6
Identities = 73/326 (22%), Positives = 115/326 (35%), Gaps = 32/326 (9%)
Query: 1084 RRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAI 1143
R R R R + G SL+ RR S + S +P + + P+ + +
Sbjct: 2053 RSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSS 2112
Query: 1144 SSPETSLKS-SPVPYQDHDQPPVLK----KERPLSQTNGAHYS------PLTSDEEPGSE 1192
S S SP P P +L+ P+S A S P D + S
Sbjct: 2113 RMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSV 2172
Query: 1193 DEP-SSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDI 1251
E + +RI + ISL + PP ++ G A PA P+ S + + S I
Sbjct: 2173 PENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRI 2232
Query: 1252 GLAKSADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGF-PGSLSGADGLSPGT 1310
A +A L ++ + + + +A A A PR P +++ AD +P
Sbjct: 2233 PAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTA 2292
Query: 1311 NPAN--GCTFGGGLAADLSL---------HSFSDGASLPHK-------GPEAAGLSSPLS 1352
N G LAA LSL ++ + P GP +A ++P++
Sbjct: 2293 PAVNLAGARTPAALAA-LSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVN 2351
Query: 1353 FPSQRGKEGSDANPFLSKRQLDGLAG 1378
R S R L+G
Sbjct: 2352 IAGSRTAAALAPASLTSARMAPALSG 2377
Score = 33.1 bits (74), Expect = 2.1
Identities = 71/332 (21%), Positives = 119/332 (35%), Gaps = 39/332 (11%)
Query: 786 SQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKS 845
++ T P P+ S + S + + + P L P +P SP + A
Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMG----QAPSQSLLPPAQDQPRSP--VPSAFSDQ 2458
Query: 846 SEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVL 905
S + + + + ++S ++ S+ + +S+P V S V
Sbjct: 2459 SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGV-----------PHSDVG 2507
Query: 906 QPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATL 965
+P P+ST +Q A A AL PA + S + S + + S +S ++
Sbjct: 2508 EP--PASTGAQQPSALA--------ALQPAKERRSSSSSSSSSSSSSSSS-------SSS 2550
Query: 966 DESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASK 1025
SSSSGS + S Q + L + + PA P A+ +S
Sbjct: 2551 SSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSS 2610
Query: 1026 GDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQ---- 1081
S S S S + + ++ + S+ S SS SP + P+ +
Sbjct: 2611 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
Query: 1082 -DSRRRGRRKRASAGTPSLSAGVSPKRRALPS 1112
+ R R RK + S S SP R PS
Sbjct: 2671 GERRSRSPRKPIDSLRDSRSLSYSPVERRRPS 2702
Score = 32.7 bits (73), Expect = 2.8
Identities = 39/170 (22%), Positives = 63/170 (37%), Gaps = 22/170 (12%)
Query: 335 REEQEAARRRQQRESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKA 394
RE ++++++++ R + + P K + S ++ K +T P +A
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPK------SKRKSKDKKRKRSRSTTPAPKSRRA 260
Query: 395 -RKKKLNKKGRKMAGRKRGRP---KKMNTANPERKP-----KKNQTALDALHAQTVSQTA 445
R + R R R K TA R P ++ + T S
Sbjct: 261 HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR 320
Query: 446 ASSPQDAYRSPHSPFY-----QLPPSVQRHSPNP--LLVAPTPPALQKLL 488
SSP+ A + P SP+ + S R SP+P P PPA LL
Sbjct: 321 PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLL 370
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 52.4 bits (124), Expect = 3e-06
Identities = 141/541 (26%), Positives = 202/541 (37%), Gaps = 89/541 (16%)
Query: 737 QYLASPLDQEV-VPCTPSHVGRPRLEKLSGLAAPDYTR--LSPAKIVLRRHLSQDHTVPG 793
QY+ L Q++ V P+ + SG A R L P + L+ PG
Sbjct: 826 QYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPG 885
Query: 794 RPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRER 853
P + S ++ P Q+P GS +L P + L P LA S +G
Sbjct: 886 IPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLP--GKVLVP----LAAPSMSVRG---- 935
Query: 854 AYGSSGE--LITSLPISIPLST--------VQPNKLPVSIP--LASVVLPSRAERARSTP 901
G +G+ + S P S+P+ +Q +PVS P L + P+ S P
Sbjct: 936 --GGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQP 993
Query: 902 SPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAE 961
VL P T + G +A P G S A S AG+ S P +
Sbjct: 994 QKVLLPSSTRITYVQSAGGHA----------LPLGTSPASS------QAGTVTSYGPTSS 1037
Query: 962 PATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLP 1021
A L +S S A V S Q P LLA + + P+ QL P A GP+
Sbjct: 1038 VA-LGFTSLGPSGPAFVQPLLSAGQAP-LLAPGQVGVSPVPSPQL---PPACAAPGGPVI 1092
Query: 1022 EA--SKGDLPSDSGFSDPESEAKRRIVFTITTGA--GSAKQSPSSKHSPLTAS-ARGDCV 1076
A S P+ S S+A +V+T+ T +A P +P TA+ A
Sbjct: 1093 TAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPF 1152
Query: 1077 PSHGQDSRRRGR-RKRASAGTPSLSAGVSPKRRALP---SVAGLFTQPSGSPLNLNSMVS 1132
PS S +A +P V ++P AG +P +P
Sbjct: 1153 PSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAP-------- 1204
Query: 1133 NINQPLE---ITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEP 1189
QPLE + ++PE+ L+ P P PP L P + T A SP P
Sbjct: 1205 --RQPLEPGPVREPTAPESELEGQPTP----PAPPPL----PETWTPTARSSP----PLP 1250
Query: 1190 GSEDEPSSAR----IERKIATISLESKSPPKTLENGG---GLAGRKPAPAGEPVNSSKWK 1242
+E +SA+ + K + S + + P + LEN G PAPA P SS+
Sbjct: 1251 PPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESS 1310
Query: 1243 S 1243
S
Sbjct: 1311 S 1311
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 51.6 bits (122), Expect = 6e-06
Identities = 71/284 (25%), Positives = 118/284 (41%), Gaps = 34/284 (11%)
Query: 423 ERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPS--------VQRHSPNP 474
E +P + + L L Q Q Q PH Q P +Q+
Sbjct: 81 ETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQS 140
Query: 475 LLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLS 534
+ P LQ + + ++Q Q + Q + LQ QE+ Q+L +QL
Sbjct: 141 VHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQ----QVLQQQEQLQQ 196
Query: 535 HCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRG 594
Q Q+ L QQ+ ++L L+Q Q+++ QQ ++Q EQL+Q + L
Sbjct: 197 QVQEQQ-----LLQQQQEQL-----QQQQLLQQQEQLQ--QQQFQQQQEQLQQQQQLLLL 244
Query: 595 QSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQ 654
Q L+ + LQ A L + L +++ L+ Q+ +Q+ L+ Q L+ Q+Q+
Sbjct: 245 QQQGQLQQQL--LQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQ--QQQE 300
Query: 655 ELLQLKSCVPP-----DDALSLHLRGKGALGRELEPDASRLHLE 693
+L Q + PP ++ + L L LG E E + R LE
Sbjct: 301 QLQQQQLQPPPLEPEEEEEVELELMPVD-LGSEQELEQQRQELE 343
Score = 47.0 bits (110), Expect = 1e-04
Identities = 64/252 (25%), Positives = 109/252 (43%), Gaps = 37/252 (14%)
Query: 439 QTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFKIQYLQF 498
Q +SQ Q + P QL Q+ P + Q+ L++ + Q Q
Sbjct: 128 QQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQV 187
Query: 499 LAYTKTPQYKASLQELLGQEKEK--NAQLLGAAQQLLSH-CQAQKEEIRRL--------- 546
L + Q + Q+LL Q++E+ QLL +QL Q Q+E++++
Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQ 247
Query: 547 --------------FQQKLDELGVKALTYNDLIQAQKEISAHNQQ--LREQSEQLEQDNR 590
QQ+L E L L+Q Q+++ QQ L++Q EQL+Q
Sbjct: 248 GQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQL 307
Query: 591 ALRGQSLQLLKARCEELQLDWATLSL---EKLLKEKQAL-KSQISEKQRHCLELQISIVE 646
Q L EE++L+ + L ++L +++Q L + Q E+Q+ +LQ+ + E
Sbjct: 308 ----QPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQE 363
Query: 647 LEKSQRQQELLQ 658
E Q +Q+L Q
Sbjct: 364 -ELQQLEQQLEQ 374
Score = 43.5 bits (101), Expect = 0.002
Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 41/221 (18%)
Query: 449 PQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPA-----LQKLLESFKIQYLQFLAYTK 503
PQ+ SP P P + T P LQ+L + + Q +
Sbjct: 57 PQERNSSPQRPAVSAPVGASE------IAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQ 110
Query: 504 TPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYND 563
PQ LQ+ Q+ ++ L + H Q K E++ + QQ+ +L + +
Sbjct: 111 QPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQ--QLQPQQVQEQQ 168
Query: 564 LIQAQKEI----SAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKL 619
+Q Q+E A QQ+ +Q EQL+Q + Q QLL+ + E+LQ ++L
Sbjct: 169 RLQQQQEQLQTQQAQEQQVLQQQEQLQQ-----QVQEQQLLQQQQEQLQQ-------QQL 216
Query: 620 LKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK 660
L++++ L+ Q ++Q+ E+ Q+QQ+LL L+
Sbjct: 217 LQQQEQLQQQQFQQQQ------------EQLQQQQQLLLLQ 245
Score = 33.5 bits (75), Expect = 1.6
Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 34/161 (21%)
Query: 485 QKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQL------------------- 525
Q+LLE + Q Q L + Q + Q+ L Q++++ Q
Sbjct: 264 QQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELE 323
Query: 526 -----LGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLRE 580
LG+ Q+L + Q++E+ R QQ+L+ + ++ Q+E+ QQL +
Sbjct: 324 LMPVDLGSEQEL----EQQRQELER--QQELERQQEQRQLQ---LKLQEELQQLEQQLEQ 374
Query: 581 QSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLK 621
Q +QLEQ L ++ L A+ +E+QL+ + E L+
Sbjct: 375 QQQQLEQQEVQLELTPVE-LGAQQQEVQLELTPVQPELQLE 414
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 51.2 bits (121), Expect = 8e-06
Identities = 92/393 (23%), Positives = 137/393 (34%), Gaps = 59/393 (15%)
Query: 831 RPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVL 890
+P PG LQ + + G++ L +P+ P P + P+S P
Sbjct: 405 QPKEPGPLQCEAKPLGKAGVQLEPQ-LEAPLNEEMPLLPP-----PEESPLSPPPEESPT 458
Query: 891 PSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALA 950
E +R +P P P P L + + SR L +P +S
Sbjct: 459 SPPPEASRLSPPPEELPASP---LPEALHL------SRPLEESP----------LSPPPE 499
Query: 951 GSPASLTPGAEP-ATLDESSSSGSLFATVGSRSSTPQHPLLLAQP-----RNSLPASPAH 1004
SP S P + P + L+ES S + TP P A P S + P
Sbjct: 500 ESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPE 559
Query: 1005 QLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKH 1064
+L +SP + P PE S P + P EA R + + SP +
Sbjct: 560 ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR-----LFPPFEESPLSPPPEE 614
Query: 1065 SPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSP 1124
SPL+ + +DS + + P + +SP LP V+ L P SP
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP----LPVVSRLSPPPEESP 670
Query: 1125 LNLNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPP-------VLKKERPL----- 1172
L+ S + P E + +S P +SP P PP + +E PL
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 1173 -----SQTNGAHYSPLTSDEEPGSEDEPSSARI 1200
++ G H SP EEP P +
Sbjct: 731 EPQLCPRSEGPHLSP--RPEEPHLSPRPEEPHL 761
Score = 42.4 bits (98), Expect = 0.004
Identities = 121/544 (22%), Positives = 194/544 (35%), Gaps = 76/544 (13%)
Query: 512 QELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEI 571
Q+ Q++ A L Q L+SH K L Q + L + L +Q Q+++
Sbjct: 3860 QQQQHQQQGSMAGLSHLQQSLMSHSGQPK-----LSAQPMGSL--QQLQQQQQLQQQQQL 3912
Query: 572 SAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQIS 631
QQ +Q +QL+Q + Q QL + + ++LQ L + +++Q + Q
Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ---QQQQQQQFQQQ 3969
Query: 632 EKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPDASRLH 691
++Q+ L S L Q+QQ+ + L +P H GALG P
Sbjct: 3970 QQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPL--QHFSSPGALG----PTLLLTG 4023
Query: 692 LELDCTKFSLPHLSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPL--DQEVVP 749
E + ++ ++ P G A + + P S P + L D +++
Sbjct: 4024 KEQNTVDPAVSSEATEGPSTHQGGPLA------IGTTPESMATEPGEVKPSLSGDSQLLL 4077
Query: 750 CTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKE 809
P +P S L RL + ++ +S HT G + +L S ++
Sbjct: 4078 VQPQPQPQP-----SSLQLQPPLRLPGQQ---QQQVSLLHTA-GGGSHGQLGS-GSSSEA 4127
Query: 810 NGLPY--QSPSV-----PGSMK---LSPQD------------PRPLSPGALQLAGEKSSE 847
+ +P+ PSV PGSM L PQ P+P PG + +G+
Sbjct: 4128 SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPG 4187
Query: 848 KGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQP 907
G+ +L L + L + P + L +++ R TP P +P
Sbjct: 4188 VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTP-PYQEP 4246
Query: 908 RDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDE 967
+S L+ +G G P AG G P P P L
Sbjct: 4247 GTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGP-----RPQGPPRLPAP---PGALST 4298
Query: 968 SSSSGSLFAT-VGSRSSTPQHPLLLAQPRNSLPAS----PAHQLSSSPRLGGAAQGPLPE 1022
G + T S P+ P L P + LP P H + P QGP E
Sbjct: 4299 GPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP------QGPTLE 4352
Query: 1023 ASKG 1026
G
Sbjct: 4353 PPPG 4356
Score = 40.8 bits (94), Expect = 0.010
Identities = 62/233 (26%), Positives = 83/233 (35%), Gaps = 29/233 (12%)
Query: 702 PHLSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTP-----SHVG 756
PHLS EL ++ Q L V P + SP +E PC SH+
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE--PCLSPRPEESHLS 852
Query: 757 RPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQS 816
P LEK P+ P + L PG P+ S L E G P S
Sbjct: 853 -PELEKPPLSPRPEKPPEEPGQCPAPEELPL-FPPPGEPSLSPLLGEPA-LSEPGEPPLS 909
Query: 817 P-------SVPGSMKLSPQD------PRPLSPGALQLAGEKSSEKGLRERAYGSSGELIT 863
P S G LSPQ P PLSP A S G E +G+ G+
Sbjct: 910 PLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDP 969
Query: 864 SLPISIPLSTVQPNKLPVS-----IPLASVVLPSRAERARSTPSPVL-QPRDP 910
P++ P+ + P + P+ ++LP SP+L +P P
Sbjct: 970 ESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP 1022
Score = 38.5 bits (88), Expect = 0.051
Identities = 93/358 (25%), Positives = 126/358 (35%), Gaps = 65/358 (18%)
Query: 806 HTKENGLPYQSPSVPGSMKLSPQDPR------PLSPGALQLAGEKSSEKGLRERAYGSSG 859
HT G P PS P L P+ P P SPG + G K+SE L +G S
Sbjct: 2227 HTTPPGTPRHQPSTPDPF-LKPRCPSLDNLAVPESPG---VGGGKASEPLLSPPPFGESR 2282
Query: 860 ELIT----SLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLE 915
+ + L S P S PN V P + L + TP P P ++
Sbjct: 2283 KALEVKKEELGASSP-SYGPPNLGFVDSPSSGTHLGGLELK---TPDVFKAPLTPRAS-- 2336
Query: 916 KQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLF 975
Q+ + G G R PA ALA SP S P + + + L
Sbjct: 2337 -QVEPQSPGLGLRPQEPPPAQ-----------ALAPSPPSHPDIFRPGSYTDPYAQPPLT 2384
Query: 976 ATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL---PEASKGDLP--- 1029
R P A P SLP+ P ++ +SP+ ++Q PL P +++ P
Sbjct: 2385 P----RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPV 2440
Query: 1030 -----SDSGFSDPESEAKRRIVFT------------ITTGAGS-AKQSPSSKHSP--LTA 1069
S +S P S + R F + AGS A S + P L A
Sbjct: 2441 TPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPA 2500
Query: 1070 SARGDC---VPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSP 1124
G+ VPS + R A GTPS P+ PS+ QP P
Sbjct: 2501 GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP 2558
Score = 35.8 bits (81), Expect = 0.33
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 493 IQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKL- 551
+ +LQ + + Q K S Q + ++ + Q L QQL Q Q ++ ++L QQ+L
Sbjct: 3873 LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQ 3932
Query: 552 ---DELGVKALTYNDLIQAQKEISAHNQQLREQ-SEQLEQDNRALRGQSLQLLKARCEEL 607
+ ++ L Q Q+++ QQ ++Q +Q +Q L QS LL + ++
Sbjct: 3933 QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQ 3992
Query: 608 Q 608
Q
Sbjct: 3993 Q 3993
Score = 34.7 bits (78), Expect = 0.73
Identities = 122/530 (23%), Positives = 174/530 (32%), Gaps = 106/530 (20%)
Query: 709 PELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAA 768
P S G A + G SRP + Q + P P TP +PR L LA
Sbjct: 2198 PYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV 2257
Query: 769 PD----------YTRLSP--------AKIVLRRHLSQDHTVPGRPAASELHSRAEHTKEN 810
P+ LSP A V + L G P + S + T
Sbjct: 2258 PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLG 2317
Query: 811 GLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLP---- 866
GL ++P V PL+P A Q+ +S GLR + + L S P
Sbjct: 2318 GLELKTPDV---------FKAPLTPRASQVE-PQSPGLGLRPQEPPPAQALAPSPPSHPD 2367
Query: 867 ISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAG 926
I P S P P PL P E + P P P DP S ++ A+
Sbjct: 2368 IFRPGSYTDPYAQP---PLTPRPQPPPPESCCALP-PRSLPSDPFS----RVPASPQSQS 2419
Query: 927 SRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQ 986
S L P S A A P+ +TP + S ++ SR +
Sbjct: 2420 SSQSPLTPRPLS---------AEAFCPSPVTPRFQ---------SPDPYSRPPSRPQSRD 2461
Query: 987 HPLLLAQPRNSLP---ASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKR 1043
L +P P A A L+ + G LP G+L + P +
Sbjct: 2462 PFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN---- 2517
Query: 1044 RIVFTITTGAGSAKQSPSSKHSPLTASA----------RGDCVPSHGQDSRRRGRRKRAS 1093
F + G G+ +PS + + P HG +S
Sbjct: 2518 ---FVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSH--------F 2566
Query: 1094 AGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSS 1153
P+L P+ G F PSGSPL +S + + ++ + P +
Sbjct: 2567 GPGPTLG---KPQSTNYTVATGNF-HPSGSPLGPSS--GSTGESYGLSPLRPPSVLPPPA 2620
Query: 1154 P---VPYQDHD-------QPPVLKKERPLSQTNGAHYSPLTSDEEPGSED 1193
P +PY H PV K+E P + S L + E PG++D
Sbjct: 2621 PDGSLPYLSHGASQRSGITSPVEKREDPGTGMG----SSLATAELPGTQD 2666
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 50.8 bits (120), Expect = 1e-05
Identities = 132/570 (23%), Positives = 201/570 (35%), Gaps = 115/570 (20%)
Query: 794 RPAASELHSRAEHTKENG-----LPYQSP-SVPGSMKLSPQDPRPLSPGALQLAGEKSSE 847
RP +HS + + L SP VP S+ P P+ P + LA SS
Sbjct: 1372 RPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPI-PNSSPLASPVSST 1430
Query: 848 KGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTP-SPVLQ 906
+ L +SLPIS+P + P P++IP+++ + S + A T +P L
Sbjct: 1431 VSV---------PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLA 1481
Query: 907 PRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLD 966
P P+ A G S LAP+G S + S A++ LA +P+
Sbjct: 1482 PVVPA----------APGPPS----LAPSGASPSAS-ALTLGLATAPSL----------- 1515
Query: 967 ESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKG 1026
S S TP HPLLLA + +P L+S+ + A L AS
Sbjct: 1516 -------------SSSQTPGHPLLLAPTSSHVPG-----LNST--VAPACSPVLVPASAL 1555
Query: 1027 DLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRR 1086
P S + ++A ++ A SA Q+ ++ +P+ A PS
Sbjct: 1556 ASPFPSAPNPAPAQA------SLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPL 1609
Query: 1087 GRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSP 1146
+ P L++ +P +P +A PS +P + S + P + A SS
Sbjct: 1610 PVLAPSPGAAPVLASSQTP----VPVMA-----PSSTPGTSLASASPVPAPTPVLAPSST 1660
Query: 1147 ETSLKSS-PVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSED----------EP 1195
+T L + P P L L+ T G T G+ P
Sbjct: 1661 QTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTP 1720
Query: 1196 SSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVN------------------ 1237
+S+ + T+SL + PP LA P PV
Sbjct: 1721 ASSLVPTPAQTLSL-APGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASL 1779
Query: 1238 ---SSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRK 1294
+S T SP L +A L + A +Q+ + S A L
Sbjct: 1780 LAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVS 1839
Query: 1295 GFPGSLSGADGLS----PGTNPANGCTFGG 1320
P S D L+ P + P+ +FGG
Sbjct: 1840 RLPVSKDEPDTLTLRSGPPSPPSTATSFGG 1869
Score = 34.3 bits (77), Expect = 0.95
Identities = 117/534 (21%), Positives = 168/534 (31%), Gaps = 160/534 (29%)
Query: 862 ITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGAN 921
IT LP+ I S P+++P P +S P+ TP P P + L
Sbjct: 2474 ITILPVHILPSPPPPSQIP---PCSS---PACTPPPACTPPPAHTPPPAQTCLV------ 2521
Query: 922 AHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSR 981
S L L P SV IS ++ P L P AE +S A+V S
Sbjct: 2522 ---TPSSPLLLGPP------SVPISASVTNLPLGLRPEAELCAQALASPESLELASVASS 2572
Query: 982 SSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEA 1041
++ L L P++ LP + S L P G +P+
Sbjct: 2573 ETS---SLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPN----------- 2618
Query: 1042 KRRIVFTITTGAGSAKQSP-SSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLS 1100
G +++P S++ + LT G+ +P L
Sbjct: 2619 ------------GQEQEAPDSAEGTTLTVLPEGEELP---------------------LC 2645
Query: 1101 AGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQDH 1160
S PS A S PL +PLE S T K+
Sbjct: 2646 VSESNGLELPPSAA------SDEPL---------QEPLEADRTSEELTEAKT-------- 2682
Query: 1161 DQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLEN 1220
P E+P +P TS S + PS AR R+ + +E +
Sbjct: 2683 ---PTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIR-------- 2731
Query: 1221 GGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALE 1280
G GR P G V + + + L + A+S T P +
Sbjct: 2732 -GQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAAS--------TLVPGVS 2782
Query: 1281 EPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHK 1340
E SA PGS S P ++P P
Sbjct: 2783 ETSAS-----------PGSPSVRSMSGPESSP-------------------------PIG 2806
Query: 1341 GPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGL 1394
GP A SS L P Q+ PF+++R ++ G+ G GS E G+G L
Sbjct: 2807 GPCEAAPSSSLPTPPQQ--------PFIARRHIE--LGVTGGGS--PENGDGAL 2848
Score = 31.6 bits (70), Expect = 6.2
Identities = 123/531 (23%), Positives = 184/531 (34%), Gaps = 77/531 (14%)
Query: 795 PAASELHSRAE-HTKENGLPYQSPSVPGSMKLSPQDPRPLS--PGALQLAGEKSS-EKGL 850
P + EL S A T L +P ++++ P + LS P A L E S G
Sbjct: 2561 PESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQ 2620
Query: 851 RERAYGSS-GELITSLPIS--IPLSTVQPN--KLPVSI----PLASVVLPSR-AERARST 900
+ A S+ G +T LP +PL + N +LP S PL + R +E
Sbjct: 2621 EQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEA 2680
Query: 901 PSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYA--------GSVAISGALAGS 952
+P P P + ++ A + + + S +P G S A V I G G
Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATS---SPEGPSPARPPRRRTSADVEIRGQGTGR 2737
Query: 953 PASLTPGAE-----PATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLS 1007
P PG + P L L + + ++ P SP+ +
Sbjct: 2738 PGQ-PPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSM 2796
Query: 1008 SSPRLGGAAQGPLPEASKGDLPSDSGFSDPESE--AKRRIVFTITTGAGSAKQSPSSKHS 1065
S P GP A LP + P+ A+R I +T G SP +
Sbjct: 2797 SGPESSPPIGGPCEAAPSSSLP-----TPPQQPFIARRHIELGVTGGG-----SPENGDG 2846
Query: 1066 PLTASARGDCVPSHGQDSRRRGR-----RKRASAG---TPSLSAGVSPKRRALPSVAGLF 1117
L A + RRRGR R A AG + S+ + K V G
Sbjct: 2847 ALLAI-------TPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPE 2899
Query: 1118 TQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQT-N 1176
T P+ L + QPL + P L SPV + +PP ++ P+ T +
Sbjct: 2900 TLIVADPV-LEPQLIPGPQPLGPQPVHRPNPLL--SPVEKRRRGRPP-KARDLPIPGTIS 2955
Query: 1177 GAHYSPLTSDEEPGSEDEP----------SSARIERKIATISLESKSPPKTLENGGGLAG 1226
A S +P P +A + + T+++ S SPPK
Sbjct: 2956 SAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTI-STSPPKRKRGRPPKNP 3014
Query: 1227 RKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRP 1277
P P+ PV + + S + GL + Q S S + RP
Sbjct: 3015 PSPRPSQLPVLD---RDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRP 3062
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 50.4 bits (119), Expect = 1e-05
Identities = 73/311 (23%), Positives = 129/311 (41%), Gaps = 35/311 (11%)
Query: 510 SLQELLGQEKEKNAQLLGAAQQLLSHCQAQK--EEIRRLFQQKLDELGVKALTYNDLIQA 567
+LQE LG+ +A L G Q LL + + E Q LD + + ++
Sbjct: 1965 ALQEALGKA---HAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRI 2021
Query: 568 QK-EISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQAL 626
Q+ EI + + +E +QL+Q A R + L+ + R + L+ A E +++EKQ L
Sbjct: 2022 QEGEIQDQDLRYQEDVQQLQQA-LAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNL 2080
Query: 627 KSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRE---- 682
+ E++ L + ++L +Q++QE+L+L+ ++ +L K + E
Sbjct: 2081 GQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLK 2140
Query: 683 LEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYL-AS 741
L+ RL EL+ + +L + E Q L + SS Q +L AS
Sbjct: 2141 LDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQAS 2200
Query: 742 PLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHT-VPGRPAASEL 800
L+++ + RL + RR L ++ PG + +EL
Sbjct: 2201 VLERD----------------------SEQQRLQDELELTRRALEKERLHSPGATSTAEL 2238
Query: 801 HSRAEHTKENG 811
SR E + G
Sbjct: 2239 GSRGEQGVQLG 2249
Score = 42.4 bits (98), Expect = 0.004
Identities = 41/175 (23%), Positives = 85/175 (48%), Gaps = 13/175 (7%)
Query: 485 QKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIR 544
Q LES ++ + +A ++ +A LQ + E + +LL AA++ L+ AQ E ++
Sbjct: 1308 QNSLESELMELHETMASLQSRLRRAELQRM---EAQGERELLQAAKENLT---AQVEHLQ 1361
Query: 545 RLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQS-LQLLKAR 603
+ + + DL A+ + N+++ + E+ + AL+ Q L++ + +
Sbjct: 1362 AAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQ----ALQEQGELKVAQGK 1417
Query: 604 CEELQLDWATLSLEKLLKEKQALKSQISE--KQRHCLELQISIVELEKSQRQQEL 656
+ L T +L + +E + L+ QI E KQR + + ++ L+ +R QE+
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEV 1472
Score = 38.9 bits (89), Expect = 0.039
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 5/182 (2%)
Query: 517 QEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKE----IS 572
QE EK ++ AA +LLS ++ + L Q+++ EL L A +E ++
Sbjct: 1445 QELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLT 1504
Query: 573 AHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISE 632
+Q+RE + E L Q L+L K L+K L + L ++ E
Sbjct: 1505 VQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALEL-E 1563
Query: 633 KQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPDASRLHL 692
+ H +E Q +++ + QR+ + + L + S L+ + + +LE ++ L
Sbjct: 1564 ENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAR 1623
Query: 693 EL 694
EL
Sbjct: 1624 EL 1625
Score = 38.5 bits (88), Expect = 0.051
Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 22/179 (12%)
Query: 503 KTPQYKASLQELLGQEKEKNAQL--LGAAQQLLSHCQAQKEEIRRLFQ-QKLDELGVKAL 559
+T A Q L EKE+ + L L Q+ L+ Q E +R+ + QKL E +
Sbjct: 909 RTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGI 968
Query: 560 TYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWAT------ 613
L +AQ+E+ +Q R+ L++++ +L + L K + E+L+
Sbjct: 969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQK-QVEDLKSQLVAQDDSQR 1027
Query: 614 ---LSLEKLLKEKQALKSQISEKQRHCLELQISIVELEK---------SQRQQELLQLK 660
+++ L+E Q E +R L +S++E E+ S RQQEL L+
Sbjct: 1028 LVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALR 1086
Score = 38.1 bits (87), Expect = 0.066
Identities = 53/205 (25%), Positives = 84/205 (40%), Gaps = 46/205 (22%)
Query: 512 QELLGQE---KEKNAQLLGAAQQLL-------SHCQAQKEEIRRLFQQKLDELGVKALTY 561
Q+ GQE KEK L GA +Q Q KE+ RRL +++L G +
Sbjct: 1827 QQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRL-EEELAVEGRRVQAL 1885
Query: 562 NDLI--------QAQKEISAHNQQLREQSEQLEQDNRALRGQSLQ---LLKARCEELQLD 610
+++ + +K + A QQ EQ+++ E + RAL+ LQ +LK R +E
Sbjct: 1886 EEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQE---- 1941
Query: 611 WATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALS 670
LE L E Q+ + Q + LQ ++ + + + +E
Sbjct: 1942 -----LEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKE--------------- 1981
Query: 671 LHLRGKGALGRELEPDASRLHLELD 695
HL + L R LE + L LD
Sbjct: 1982 QHLLEQAELSRSLEASTATLQASLD 2006
Score = 36.6 bits (83), Expect = 0.19
Identities = 41/175 (23%), Positives = 82/175 (46%), Gaps = 11/175 (6%)
Query: 487 LLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRL 546
+L+ +IQ L+ +T + L+++ +E+ +L +QL+ + + +
Sbjct: 1661 MLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELT-TQRQLMQERAEEGKGPSKA 1719
Query: 547 FQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALR---GQSLQLLKAR 603
+ L+ + + ++ Q+E H +L+E +QLEQ + L G++ LL R
Sbjct: 1720 QRGSLEHMKLILRDKEKEVECQQE---HIHELQELKDQLEQQLQGLHRKVGETSLLLSQR 1776
Query: 604 CEE---LQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQE 655
+E LQ + LKE Q+L+SQ+ E QR + + L++ Q+Q +
Sbjct: 1777 EQEIVVLQQQLQEAREQGELKE-QSLQSQLDEAQRALAQRDQELEALQQEQQQAQ 1830
Score = 35.4 bits (80), Expect = 0.43
Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 29/190 (15%)
Query: 524 QLLGA--AQQLLSHCQAQKEEIRRLFQQKLDEL-GVKALTYNDLIQAQKEISAHN----- 575
QL G A LL Q EE + +Q+L +L G + + Q E+ + +
Sbjct: 408 QLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKEREL 467
Query: 576 -----QQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQI 630
++LR+Q E LEQ+ LR +++L +LQ D A + KE+Q + +
Sbjct: 468 LQKAREELRQQLEVLEQEAWRLRRVNVEL------QLQGDSA-----QGQKEEQQEELHL 516
Query: 631 SEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPDASRL 690
+ ++R L+ + +E ++S+ EL+ L+ + S HL G+ + E A+
Sbjct: 517 AVRERERLQEMLMGLEAKQSESLSELITLREALE-----SSHLEGELLRQEQTEVTAALA 571
Query: 691 HLELDCTKFS 700
E + S
Sbjct: 572 RAEQSIAELS 581
Score = 35.0 bits (79), Expect = 0.56
Identities = 34/143 (23%), Positives = 63/143 (44%), Gaps = 21/143 (14%)
Query: 513 ELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRL-------FQQKLDELGVKALTYNDL- 564
E L E E+N + Q+L+ + Q+E R +++ EL ++ +DL
Sbjct: 1556 ECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLE 1615
Query: 565 ---IQAQKEISAHNQQLREQSEQLEQDNR---------ALRGQSLQLLKARCEELQLDWA 612
+E+ +Q+++ Q EQ+E+ R R Q L L K R + L+ D
Sbjct: 1616 SHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLE-DQR 1674
Query: 613 TLSLEKLLKEKQALKSQISEKQR 635
T + L ++ + +K + E+ R
Sbjct: 1675 TRQTKILEEDLEQIKLSLRERGR 1697
Score = 33.1 bits (74), Expect = 2.1
Identities = 22/87 (25%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
Query: 568 QKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLK-EKQAL 626
+ + HN QLR EQ+E++ R L+ ++++ +A E+ A+ ++ + +K +
Sbjct: 2286 RSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKNSD 2345
Query: 627 KSQISEKQRHCLELQISIVELEKSQRQ 653
++E Q+ + LQ + LE+ Q+Q
Sbjct: 2346 AKCVAELQKEVVLLQAQLT-LERKQKQ 2371
Score = 32.3 bits (72), Expect = 3.6
Identities = 31/124 (25%), Positives = 62/124 (50%), Gaps = 15/124 (12%)
Query: 513 ELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEIS 572
+L+ ++KEK + Q+ + Q K+++ + Q ++G +L L Q ++EI
Sbjct: 1728 KLILRDKEKEVE---CQQEHIHELQELKDQLEQQLQGLHRKVGETSLL---LSQREQEIV 1781
Query: 573 AHNQQL---REQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQ 629
QQL REQ E EQ ++ ++ + L R +EL+ +L++ ++ Q + +
Sbjct: 1782 VLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELE------ALQQEQQQAQGQEER 1835
Query: 630 ISEK 633
+ EK
Sbjct: 1836 VKEK 1839
Score = 32.0 bits (71), Expect = 4.7
Identities = 42/173 (24%), Positives = 74/173 (42%), Gaps = 25/173 (14%)
Query: 503 KTPQYKASLQELLGQEKEKNAQLLG----AAQQLLSHCQAQKEEIRRLFQQKLDELGVKA 558
K + LQ+ QE EK +L A Q+ Q+E+IR L + + + V
Sbjct: 1466 KKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLE 1525
Query: 559 LTYNDLIQAQKEISAHNQQLREQSEQL----------EQDNRALRGQSLQLLKA-----R 603
+L + + I + Q+++ +QL E+++ + Q +L+K
Sbjct: 1526 HQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQ-KLIKELEGQRE 1584
Query: 604 CEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQEL 656
+ + L TL LE+ +E QA SQ H LE +++ E +R QE+
Sbjct: 1585 TQRVALTHLTLDLEERSQELQAQSSQ-----IHDLESHSTVLARELQERDQEV 1632
Score = 31.6 bits (70), Expect = 6.2
Identities = 49/189 (25%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Query: 484 LQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQ---- 539
LQK +E K Q + + + QE+ QEK + Q Q+ L +A
Sbjct: 1008 LQKQVEDLKSQLV-----AQDDSQRLVEQEV--QEKLRETQEYNRIQKELEREKASLTLS 1060
Query: 540 --KEEIRRLFQQKLDELGVKALTY--NDLIQAQ---KEISAHNQQLREQSEQLEQDNRAL 592
++E R L Q+ D + + L+ D+ +AQ KE+SA + LR++ ++ E D A
Sbjct: 1061 LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQ 1120
Query: 593 RGQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQR 652
Q L+ L+A Q A+L ++ + L+ + +E Q L+ E + +
Sbjct: 1121 EAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQ-----LEALAAEQQPGNQ 1175
Query: 653 QQELLQLKS 661
Q QL S
Sbjct: 1176 AQAQAQLAS 1184
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 49.3 bits (116), Expect = 3e-05
Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 28/183 (15%)
Query: 490 SFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLG--------------AAQQLLSH 535
S ++QY Q + + + S L+ E+EK L +A+
Sbjct: 40 SLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYERE 99
Query: 536 CQAQKEEIRRLFQQKLDELGVKALTYNDLI---QAQKEISAHNQQLREQSEQLEQDNRAL 592
+E + R+ Q + E G + L Q Q+ + A +++LRE+ + L Q
Sbjct: 100 VDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQ----- 154
Query: 593 RGQSLQLLKARCEELQLDWATLSLEKLLK----EKQALKSQISEKQRHCLELQISIVELE 648
G+++ LK R ELQ W+ + E +K EKQ L+ Q+ + + C E I EL+
Sbjct: 155 AGETINALKGRISELQ--WSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQ 212
Query: 649 KSQ 651
SQ
Sbjct: 213 ASQ 215
Score = 31.6 bits (70), Expect = 6.2
Identities = 65/300 (21%), Positives = 120/300 (40%), Gaps = 36/300 (12%)
Query: 376 AEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTAL-- 433
A ++K A T KAR++ L ++ R+++G+ KK T + + + L
Sbjct: 347 ALKDKNSAVTSSARGLEKARQQ-LQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLT 405
Query: 434 ---DALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQR-HSPNPLLVAPTPPALQKLL- 488
D + A S + +P + + VQ+ HS + + A AL++L
Sbjct: 406 KERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGG 465
Query: 489 ESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQ 548
+ + L+ Q ++ Q L +E A L + L +++ EE +R+ +
Sbjct: 466 QKQRADMLEMELKMLKSQSSSAEQSFLFSREE--ADTLRLKVEELEGERSRLEEEKRMLE 523
Query: 549 QKLDELGVKALTYNDLIQAQKEI--------SAHNQQLREQSEQLEQDNRALRGQSLQLL 600
+L+ ++ D Q++ ++ S Q+LRE QL+ + LRG +
Sbjct: 524 AQLERRALQG----DYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAME 579
Query: 601 KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK 660
+ L+ A SL KE LK Q+ + K+QR +E+ Q K
Sbjct: 580 RGGTVPADLEAAAASLPS-SKEVAELKKQVESAEL-------------KNQRLKEVFQTK 625
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 49.3 bits (116), Expect = 3e-05
Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 28/183 (15%)
Query: 490 SFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLG--------------AAQQLLSH 535
S ++QY Q + + + S L+ E+EK L +A+
Sbjct: 40 SLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYERE 99
Query: 536 CQAQKEEIRRLFQQKLDELGVKALTYNDLI---QAQKEISAHNQQLREQSEQLEQDNRAL 592
+E + R+ Q + E G + L Q Q+ + A +++LRE+ + L Q
Sbjct: 100 VDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQ----- 154
Query: 593 RGQSLQLLKARCEELQLDWATLSLEKLLK----EKQALKSQISEKQRHCLELQISIVELE 648
G+++ LK R ELQ W+ + E +K EKQ L+ Q+ + + C E I EL+
Sbjct: 155 AGETINALKGRISELQ--WSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQ 212
Query: 649 KSQ 651
SQ
Sbjct: 213 ASQ 215
Score = 31.6 bits (70), Expect = 6.2
Identities = 65/300 (21%), Positives = 120/300 (40%), Gaps = 36/300 (12%)
Query: 376 AEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTAL-- 433
A ++K A T KAR++ L ++ R+++G+ KK T + + + L
Sbjct: 347 ALKDKNSAVTSSARGLEKARQQ-LQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLT 405
Query: 434 ---DALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQR-HSPNPLLVAPTPPALQKLL- 488
D + A S + +P + + VQ+ HS + + A AL++L
Sbjct: 406 KERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGG 465
Query: 489 ESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQ 548
+ + L+ Q ++ Q L +E A L + L +++ EE +R+ +
Sbjct: 466 QKQRADMLEMELKMLKSQSSSAEQSFLFSREE--ADTLRLKVEELEGERSRLEEEKRMLE 523
Query: 549 QKLDELGVKALTYNDLIQAQKEI--------SAHNQQLREQSEQLEQDNRALRGQSLQLL 600
+L+ ++ D Q++ ++ S Q+LRE QL+ + LRG +
Sbjct: 524 AQLERRALQG----DYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAME 579
Query: 601 KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK 660
+ L+ A SL KE LK Q+ + K+QR +E+ Q K
Sbjct: 580 RGGTVPADLEAAAASLPS-SKEVAELKKQVESAEL-------------KNQRLKEVFQTK 625
>gi|62243332 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 49.3 bits (116), Expect = 3e-05
Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 28/183 (15%)
Query: 490 SFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLG--------------AAQQLLSH 535
S ++QY Q + + + S L+ E+EK L +A+
Sbjct: 40 SLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYERE 99
Query: 536 CQAQKEEIRRLFQQKLDELGVKALTYNDLI---QAQKEISAHNQQLREQSEQLEQDNRAL 592
+E + R+ Q + E G + L Q Q+ + A +++LRE+ + L Q
Sbjct: 100 VDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQ----- 154
Query: 593 RGQSLQLLKARCEELQLDWATLSLEKLLK----EKQALKSQISEKQRHCLELQISIVELE 648
G+++ LK R ELQ W+ + E +K EKQ L+ Q+ + + C E I EL+
Sbjct: 155 AGETINALKGRISELQ--WSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQ 212
Query: 649 KSQ 651
SQ
Sbjct: 213 ASQ 215
Score = 31.6 bits (70), Expect = 6.2
Identities = 65/300 (21%), Positives = 120/300 (40%), Gaps = 36/300 (12%)
Query: 376 AEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTAL-- 433
A ++K A T KAR++ L ++ R+++G+ KK T + + + L
Sbjct: 347 ALKDKNSAVTSSARGLEKARQQ-LQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLT 405
Query: 434 ---DALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQR-HSPNPLLVAPTPPALQKLL- 488
D + A S + +P + + VQ+ HS + + A AL++L
Sbjct: 406 KERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGG 465
Query: 489 ESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQ 548
+ + L+ Q ++ Q L +E A L + L +++ EE +R+ +
Sbjct: 466 QKQRADMLEMELKMLKSQSSSAEQSFLFSREE--ADTLRLKVEELEGERSRLEEEKRMLE 523
Query: 549 QKLDELGVKALTYNDLIQAQKEI--------SAHNQQLREQSEQLEQDNRALRGQSLQLL 600
+L+ ++ D Q++ ++ S Q+LRE QL+ + LRG +
Sbjct: 524 AQLERRALQG----DYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAME 579
Query: 601 KARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK 660
+ L+ A SL KE LK Q+ + K+QR +E+ Q K
Sbjct: 580 RGGTVPADLEAAAASLPS-SKEVAELKKQVESAEL-------------KNQRLKEVFQTK 625
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 48.5 bits (114), Expect = 5e-05
Identities = 102/489 (20%), Positives = 171/489 (34%), Gaps = 55/489 (11%)
Query: 869 IPLSTVQ----PNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHG 924
IPLS ++ K+ + P ++++PS R+R T + +D + ++ GA A G
Sbjct: 2272 IPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARG 2331
Query: 925 AGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSST 984
G + A A + G+P P + P L+ SS+ GS +
Sbjct: 2332 RGRKPSAKAKGD-------RAATLEEGNPTDEVP-STPLALEPSSTPGSKKSPPEPVDKR 2383
Query: 985 PQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRR 1044
+ P P PA PA +S P A+ P P S P + P + K +
Sbjct: 2384 AKAPKARPAPPQPSPAPPA--FTSCPAPEPFAELPAPATSLAPAPL---ITMPATRPKPK 2438
Query: 1045 IVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVS 1104
+ P + L + G S + + K A AG
Sbjct: 2439 KARAAEESGAKGPRRPGEEAELLVK------LDHEGVTSPKSKKAKEALLLREDPGAGGW 2492
Query: 1105 PKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVP---YQDHD 1161
+ ++L S+ G + +GS S P + + L P P ++D
Sbjct: 2493 QEPKSLLSL-GSYPPAAGS--------SEPKAPWP----KATDGDLAQEPGPGLTFEDSG 2539
Query: 1162 QPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENG 1221
P ++ ++ +GA S +S GS SS+ + + + K + G
Sbjct: 2540 NPK--SPDKAQAEQDGAEESESSSSSSSGSSSSSSSS---SSSGSETEGEEEGDKNGDGG 2594
Query: 1222 GGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEE 1281
G GR + A S S+ S S + S+ S +SS+ S +S
Sbjct: 2595 CGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---------- 2644
Query: 1282 PSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHKG 1341
S+ + ++ S S + S T + AA S A+LP K
Sbjct: 2645 -SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA 2703
Query: 1342 PEAAGLSSP 1350
+ AG + P
Sbjct: 2704 TKQAGKARP 2712
Score = 42.0 bits (97), Expect = 0.005
Identities = 89/438 (20%), Positives = 149/438 (34%), Gaps = 61/438 (13%)
Query: 727 SRPSSKQNTPQYL--------ASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAK 778
S P SK++ P+ + A P + P P+ P E + L AP T L+PA
Sbjct: 2368 STPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPA-TSLAPAP 2426
Query: 779 IVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGS-----MKLSPQDPRPL 833
++ PA +A +E+G + P PG +KL +
Sbjct: 2427 LITM------------PATRPKPKKARAAEESGA--KGPRRPGEEAELLVKLDHE----- 2467
Query: 834 SPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSR 893
G +K+ E L G+ G +S+ S P A+ +
Sbjct: 2468 --GVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLG-----------SYPPAAGSSEPK 2514
Query: 894 AERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSP 953
A ++T + Q P T E N A S + S + SG+ + S
Sbjct: 2515 APWPKATDGDLAQEPGPGLTFEDS--GNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSS 2572
Query: 954 ASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLG 1013
+S + G+E +E +G G R+ +S ASPA SSS
Sbjct: 2573 SSSSSGSETEGEEEGDKNGDGGCGTGGRN---------CSAASSRAASPASSSSSSSSSS 2623
Query: 1014 GAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARG 1073
++ +S S S S S + + ++ + S+ S S+ + S+
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDD 2683
Query: 1074 DCVPSHGQDSRRRG---RRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSM 1130
+ P+ + + AG SA K+ P QP+ PL +
Sbjct: 2684 EAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPT-QPLQPKAQ 2742
Query: 1131 VSNINQPLEITAISSPET 1148
++P + + P T
Sbjct: 2743 AGAKSRPKKREGVHLPTT 2760
Score = 33.1 bits (74), Expect = 2.1
Identities = 19/79 (24%), Positives = 34/79 (43%)
Query: 330 KNPKLREEQEAARRRQQRESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVKKP 389
K L ++A R + +++ + GP + P + S A A + T K
Sbjct: 2028 KGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKR 2087
Query: 390 SPSKARKKKLNKKGRKMAG 408
S +KA+ K++ K+ R G
Sbjct: 2088 SKAKAKGKEVKKENRGKGG 2106
Score = 31.2 bits (69), Expect = 8.1
Identities = 84/369 (22%), Positives = 123/369 (33%), Gaps = 61/369 (16%)
Query: 1007 SSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRI----VFTITTGAGSAKQSP-- 1060
S SP L Q + + KG P GF P + A + T G G + +P
Sbjct: 138 SGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSARTPGGGHSSGAPAK 197
Query: 1061 --SSKHSPL--TASARGDCVPSHG-QDSRRRGRRK-----------------RASAGTPS 1098
SS+ P A G+ P G +D R RG R G P
Sbjct: 198 GSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPR 257
Query: 1099 LSAGVSP-------KRRAL-PSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPE--- 1147
L+ +SP K AL PSV + +G + L ++V+ + A E
Sbjct: 258 LAERLSPFLAESKTKNAALQPSVLTMCNGGAGD-VGLPALVAEAGRGGAKEAARQDEGAR 316
Query: 1148 -----TSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDE-------P 1195
+L P P PP + P + T E G E P
Sbjct: 317 LLRRTETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVP 376
Query: 1196 SSARIERKIATISLESKS-PPKTLENGGGLAGRKPAPAGEPVNSSK---WKSTFSPISDI 1251
S + + I + S++ + E G G AP G P + + S I +
Sbjct: 377 SVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSL 436
Query: 1252 GLAKSADSP-LQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPG----SLSGADGL 1306
AD+P ++A+ A + L +P AD + +G G + GL
Sbjct: 437 KRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGL 496
Query: 1307 SPGTNPANG 1315
PG P G
Sbjct: 497 EPGRPPPTG 505
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 48.1 bits (113), Expect = 6e-05
Identities = 73/327 (22%), Positives = 117/327 (35%), Gaps = 38/327 (11%)
Query: 189 DIPAKYAETMDRE--FRKWMKWYGKKHAEYTLERGDFL------SEE---WRERIANTSV 237
D P Y +T+ +R + + E L RGD + +E+ W
Sbjct: 171 DSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRG 230
Query: 238 IFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELS 297
+F +NF P +L R +E I K P + L+ T
Sbjct: 231 VFPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATT-------G 283
Query: 298 PLKGSVSWTGKPVSYYLHTIDRTILENYFS--SLKNPKLREEQEAARRRQQRESKSNAAT 355
P K S T S L + D + S S + R + + ++R + ++
Sbjct: 284 PSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSS 343
Query: 356 PTKGPE-------GKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARK--KKLNKKGRKM 406
P K P K A P P A K A K PSP K K + G
Sbjct: 344 PVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNST 403
Query: 407 AGR-----KRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFY 461
+G+ K P+KM T PE K + ++ + +T++ S+P+ + SP
Sbjct: 404 SGKIPAPDKVPTPEKMVT--PEDKASIPENSI--IPEETLTVDKPSTPERVFSVEESPAL 459
Query: 462 QLPPSVQRHSPNPLLVAPTPPALQKLL 488
+ PP + +P + P L+K+L
Sbjct: 460 EAPPMDKVPNPKMAPLGDEAPTLEKVL 486
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 48.1 bits (113), Expect = 6e-05
Identities = 73/327 (22%), Positives = 117/327 (35%), Gaps = 38/327 (11%)
Query: 189 DIPAKYAETMDRE--FRKWMKWYGKKHAEYTLERGDFL------SEE---WRERIANTSV 237
D P Y +T+ +R + + E L RGD + +E+ W
Sbjct: 60 DSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRG 119
Query: 238 IFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELS 297
+F +NF P +L R +E I K P + L+ T
Sbjct: 120 VFPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATT-------G 172
Query: 298 PLKGSVSWTGKPVSYYLHTIDRTILENYFS--SLKNPKLREEQEAARRRQQRESKSNAAT 355
P K S T S L + D + S S + R + + ++R + ++
Sbjct: 173 PSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSS 232
Query: 356 PTKGPE-------GKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARK--KKLNKKGRKM 406
P K P K A P P A K A K PSP K K + G
Sbjct: 233 PVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNST 292
Query: 407 AGR-----KRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFY 461
+G+ K P+KM T PE K + ++ + +T++ S+P+ + SP
Sbjct: 293 SGKIPAPDKVPTPEKMVT--PEDKASIPENSI--IPEETLTVDKPSTPERVFSVEESPAL 348
Query: 462 QLPPSVQRHSPNPLLVAPTPPALQKLL 488
+ PP + +P + P L+K+L
Sbjct: 349 EAPPMDKVPNPKMAPLGDEAPTLEKVL 375
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 48.1 bits (113), Expect = 6e-05
Identities = 85/342 (24%), Positives = 119/342 (34%), Gaps = 31/342 (9%)
Query: 711 LSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLD-QEVVPCT------PSHVGRPRLEKL 763
L + G+ G + G L P+ +++ L QE +P H RP LE L
Sbjct: 572 LVLQGEGEGPQAQGPLREGREVSQAPETVSALLGLQEQLPGEGLPWRLQHHPTRPALELL 631
Query: 764 SGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGL--PYQSPSVPG 821
L + L RHL Q V PA SEL R + GL Q PS+
Sbjct: 632 ELSLGAVLEALGHVLLQLGRHLVQQIIVLQAPACSELSHRTGKVGQEGLLRLLQVPSMAQ 691
Query: 822 SMKLSPQDPRPLSPGALQL-AGEKSSEKGLRERAYGS-SGELITSLPISIPLSTVQPNKL 879
LSP+ P PL + G K S R++ S +++ L P
Sbjct: 692 GTLLSPEPPEPLLMSTPEEDVGVKFSVMAWDPRSFEMLSSSWYQGESLNLTLLAGDPRSS 751
Query: 880 PVSIPLASVVLPSRAER------ARSTPSPVL-QP-RDPSSTLEKQIGANAHGAGSRSLA 931
+ LA V+ + AE+ T +L +P +P S L + A+ +R L
Sbjct: 752 SNNCRLARQVMRAPAEQLSLLAMGLDTSGTLLGRPCLEPISALMICVEADTRPGSARRLT 811
Query: 932 LAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLL 991
L PAG S S P P A SS+ S ++GS H
Sbjct: 812 LQPAGASLPSREWSSPGSTSGPLRPPPAAPVV-----SSANSYVMSMGSSGMLSSHSRTT 866
Query: 992 AQPRNSLPASPAHQLSSSPRLGGAAQGPLP--EASKGDLPSD 1031
A +L +P GP P + D P D
Sbjct: 867 ASGDER-----GRELGDTPLASSCPWGPPPLLKVFSSDSPRD 903
Score = 38.9 bits (89), Expect = 0.039
Identities = 93/410 (22%), Positives = 147/410 (35%), Gaps = 57/410 (13%)
Query: 991 LAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAK-------- 1042
++ P S AS + +S+P G A P AS +PSDSG++ P +
Sbjct: 12 VSTPSGSGWASSSASGASTPSNSGWAS---PSASGASIPSDSGWASPSASGASTPSNSGW 68
Query: 1043 ---RRIVFTITTGAGSAKQSPSSKHSP-----LTASARGDCVPSHGQ-----------DS 1083
+I + +G A S S +P + SA G +PS S
Sbjct: 69 ASFSASWASIPSDSGWASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSGASIPS 128
Query: 1084 RRRGRRKRASAGTPSLSAGVSPKRR----------ALPSVAGLFTQPSGSPLNLNSMVSN 1133
+ A TPS S SP A PS + +T PS S +S S
Sbjct: 129 AFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSAS--WTSPSAS--CASSSASG 184
Query: 1134 INQPLEITAIS------SPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDE 1187
+ P + S SP TS SSP + P + + ++ + SP S
Sbjct: 185 ASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTP----SDSGWASSSASCISPSASGA 240
Query: 1188 EPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSP 1247
S+ +S + S S S + + +G S+ W S+ +
Sbjct: 241 STSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSAS 300
Query: 1248 ISDIGLAKSADSP-LQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGL 1306
+ + SP + +S LS + +F + +D+ +H G + S +
Sbjct: 301 WASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASGV-STTSDSGWA 359
Query: 1307 SPGTNPANGCTFGGGLAADLSLHSFS-DGASLPHKGPEAAGLSSPLSFPS 1355
SP + A+ + G + S S S GAS P A+ +S S PS
Sbjct: 360 SPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGASMPS 409
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 48.1 bits (113), Expect = 6e-05
Identities = 47/221 (21%), Positives = 96/221 (43%), Gaps = 15/221 (6%)
Query: 512 QELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEI 571
+ +L ++ + +L A+++ + A+K+E+ + + + L +K++
Sbjct: 889 KNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKM 948
Query: 572 SAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLE----KLLKEKQALK 627
AH Q L EQ L+++ A + L+ + A + +++ L LE K +KEK+ ++
Sbjct: 949 QAHIQDLEEQ---LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 628 SQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPDA 687
+I+E E + L K + +QE++ L L+ + +ELE
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVM--------ISDLEERLKKEEKTRQELEKAK 1057
Query: 688 SRLHLELDCTKFSLPHLSSMSPELSMNGQAAGYELCGVLSR 728
+L E + + L + EL + EL G L+R
Sbjct: 1058 RKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
Score = 37.0 bits (84), Expect = 0.15
Identities = 46/191 (24%), Positives = 91/191 (47%), Gaps = 24/191 (12%)
Query: 485 QKLLESFKIQYLQFLAYTKTPQYK--------ASLQELLGQEKE---KNAQLLGAAQQLL 533
Q+ L + K+ AY K ++ L ++ QE+E K+ +LL ++
Sbjct: 810 QQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQ- 868
Query: 534 SHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALR 593
+ + + EE+ R QQ L+E + A + +QA+ E+ A +++R + +Q+ +
Sbjct: 869 TKVEGELEEMERKHQQLLEEKNILA----EQLQAETELFAEAEEMRARLAAKKQELEEI- 923
Query: 594 GQSLQLLKARCEELQLDWATLSLE--KLLKEKQALKSQISEKQ--RHCLELQISIVELEK 649
L L++R EE + L E K+ Q L+ Q+ E++ R L+L+ E +
Sbjct: 924 ---LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI 980
Query: 650 SQRQQELLQLK 660
+ ++E+L L+
Sbjct: 981 KKMEEEILLLE 991
Score = 36.2 bits (82), Expect = 0.25
Identities = 48/192 (25%), Positives = 89/192 (46%), Gaps = 35/192 (18%)
Query: 509 ASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQ 568
A+ QEL + +++ A+L A ++ + +AQ +++R+ L+EL ++ ++
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEEL-------SEQLEQA 1215
Query: 569 KEISAHNQQLREQSEQLEQDNR--ALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQAL 626
K A+ L + + LE DN+ A + LQ +KA E + +KL + Q L
Sbjct: 1216 KRFKAN---LEKNKQGLETDNKELACEVKVLQQVKAESEHKR--------KKLDAQVQEL 1264
Query: 627 KSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPD 686
+++SE R L++ + E + S+ Q EL D +S L G + D
Sbjct: 1265 HAKVSEGDR----LRVELAE-KASKLQNEL----------DNVSTLLEEAEKKGIKFAKD 1309
Query: 687 ASRLHLELDCTK 698
A+ L +L T+
Sbjct: 1310 AASLESQLQDTQ 1321
Score = 35.0 bits (79), Expect = 0.56
Identities = 47/213 (22%), Positives = 94/213 (44%), Gaps = 21/213 (9%)
Query: 511 LQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQ-- 568
LQ++ + + K +L Q+L + ++ + +R +K +L + + L++
Sbjct: 1243 LQQVKAESEHKRKKLDAQVQELHAKV-SEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1301
Query: 569 ------KEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLK- 621
K+ ++ QL++ E L+++ R S ++ + E+ L E+ K
Sbjct: 1302 KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1361
Query: 622 -EKQ--ALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGA 678
EKQ AL+SQ+++ ++ + +I LE+++ K + +ALS L K
Sbjct: 1362 LEKQVLALQSQLADTKKKVDDDLGTIESLEEAK--------KKLLKDAEALSQRLEEKAL 1413
Query: 679 LGRELEPDASRLHLELDCTKFSLPHLSSMSPEL 711
+LE +RL ELD L H ++ L
Sbjct: 1414 AYDKLEKTKNRLQQELDDLTVDLDHQRQVASNL 1446
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 48.1 bits (113), Expect = 6e-05
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 29/194 (14%)
Query: 518 EKEKNA---------QLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQ 568
EKEK+A + + A ++ +S +K+ ++ QQ LD+L V+ N LI+
Sbjct: 969 EKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKIN 1028
Query: 569 KEISAHNQQLREQSEQ-------LEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLK 621
++ L EQ LE+ R L G L++ + +L+ D +E+ LK
Sbjct: 1029 AKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGD-LKMSQESIMDLEND--KQQIEEKLK 1085
Query: 622 EKQ----ALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHL-RGK 676
+K+ L+++I ++Q H L+ Q I EL Q + +L+ + + L + + +
Sbjct: 1086 KKEFELSQLQAKIDDEQVHSLQFQKKIKEL-----QARIEELEEEIEAEHTLRAKIEKQR 1140
Query: 677 GALGRELEPDASRL 690
L RELE + RL
Sbjct: 1141 SDLARELEEISERL 1154
Score = 32.7 bits (73), Expect = 2.8
Identities = 40/174 (22%), Positives = 75/174 (43%), Gaps = 12/174 (6%)
Query: 484 LQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEI 543
LQ ++ ++ LQF K + +A ++EL E+E A+ L + + Q+ ++
Sbjct: 1094 LQAKIDDEQVHSLQF--QKKIKELQARIEEL---EEEIEAE-----HTLRAKIEKQRSDL 1143
Query: 544 RRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKAR 603
R ++ + L + + I+ K+ A Q++R E+ + A +
Sbjct: 1144 ARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADS 1203
Query: 604 CEEL--QLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQE 655
EL Q+D +KL KEK LK +I + + L S +E++ R E
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVE 1257
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 48.1 bits (113), Expect = 6e-05
Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 19/176 (10%)
Query: 486 KLLESFKIQYLQFL-----AYTKTPQYKASLQELLGQEKEKNAQLLGA---AQQLLSHCQ 537
K LES K Q + L ++ KT + + S Q L + + L + QQL S Q
Sbjct: 728 KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Query: 538 AQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSL 597
+ E + L Q+ L+EL + + L + K + QL + +QLE++N+ LR Q
Sbjct: 788 DLEMENQTL-QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ-- 844
Query: 598 QLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQ 653
A ++ L+ + + L KE + L +I + C+ L+ ELEK ++
Sbjct: 845 ----AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLK----ELEKENKE 892
Score = 43.9 bits (102), Expect = 0.001
Identities = 49/215 (22%), Positives = 101/215 (46%), Gaps = 30/215 (13%)
Query: 508 KASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGV--KALTYNDLI 565
KA ++ L + +EK QLL Q+L + + E++RL Q+ ++ L A Y D +
Sbjct: 257 KAKIRRLRQELEEKTEQLLDCKQEL----EQMEIELKRLQQENMNLLSDARSARMYRDEL 312
Query: 566 QAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATL-----SLEKLL 620
A +E + +L + + ++ R ++ KAR EEL+ D L LE L
Sbjct: 313 DALREKAVRVDKLESEVSRYKE-----RLHDIEFYKARVEELKEDNQVLLETKTMLEDQL 367
Query: 621 KEKQALKSQISEKQRHCLELQISI--VELEKSQRQQELLQLKSCVPPDDALSLHLRGKGA 678
+ +A ++ E ++ L+L+ + +E+E+ ++++ +L ++ ++L + K +
Sbjct: 368 EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM-----EENMTLEMAQKQS 422
Query: 679 LGRELEPDASRLHLELDCTKFSLPHLSSMSPELSM 713
+ LHL + + S S +P+ S+
Sbjct: 423 MDES-------LHLGWELEQISRTSELSEAPQKSL 450
Score = 38.9 bits (89), Expect = 0.039
Identities = 63/272 (23%), Positives = 117/272 (43%), Gaps = 26/272 (9%)
Query: 410 KRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQR 469
KR + + MN + R + + LDAL + V S Y+ V+
Sbjct: 289 KRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEE 348
Query: 470 HSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTP-QYKASLQEL----------LGQE 518
+ ++ T L+ LE + + + K Q KA L ++ + +
Sbjct: 349 LKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEEL 408
Query: 519 KEKNAQLLGAAQQLLS---HCQAQKEEIRRLFQQKLDELGVKALTY--NDLIQAQK-EIS 572
E+N L A +Q + H + E+I R +L E K+L + N+L ++ ++
Sbjct: 409 MEENMTLEMAQKQSMDESLHLGWELEQISRT--SELSEAPQKSLGHEVNELTSSRLLKLE 466
Query: 573 AHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLE-KLLKEKQALK---- 627
NQ L + E+L ++ G + ++LK E +L LE ++++EKQ+L+
Sbjct: 467 MENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Query: 628 -SQISEKQRHCLELQISIVELEKSQRQQELLQ 658
S+ K++ LE I + E S+RQ ++L+
Sbjct: 527 LSKDLMKEKAQLEKTIETLR-ENSERQIKILE 557
Score = 38.9 bits (89), Expect = 0.039
Identities = 47/212 (22%), Positives = 90/212 (42%), Gaps = 30/212 (14%)
Query: 508 KASLQELLGQEKEKNAQLLGAAQQL---LSHCQAQKEEIRRLFQQKLDELGVKALTYNDL 564
K +++ L KEK + A++L L H + + E L Q+K+ L + L
Sbjct: 610 KRQIKKELEHYKEKGER----AEELENELHHLEKENE----LLQKKITNLKITCEKIEAL 661
Query: 565 IQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQ 624
Q E+ N++L++ + + + + QL E QLD L L + ++ +
Sbjct: 662 EQENSELERENRKLKKTLD-------SFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Query: 625 ALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELE 684
++++ L+L+ +E EK Q ++ L LK+ + L + +G L+
Sbjct: 715 CASMKMAQ-----LQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG-------LD 762
Query: 685 PDASRLHLELDCTKFSLPHLSSMSPELSMNGQ 716
+ RL L+ + + L S +L M Q
Sbjct: 763 IENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Score = 35.8 bits (81), Expect = 0.33
Identities = 46/196 (23%), Positives = 90/196 (45%), Gaps = 45/196 (22%)
Query: 503 KTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIR-RLFQQKLDELGVKALTY 561
KT Q L++L E EK +G ++ L H + ++ R +L + KL+ K+L
Sbjct: 917 KTQQMNNDLEKLT-HELEK----IGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI 971
Query: 562 ND----LIQAQKEISA-HNQQLREQSEQLEQDNRALRGQ--------------------- 595
+ ++A+ E S +NQQLR++ + ++++ AL+ +
Sbjct: 972 KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWE 1031
Query: 596 ------SLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEK 649
+ +LLK + ++++ +L+ EKQALK+Q+ + + LQ I+ L++
Sbjct: 1032 RESQETTRELLKVKDRLIEVERNNATLQA---EKQALKTQLKQLETQNNNLQAQILALQR 1088
Query: 650 S----QRQQELLQLKS 661
Q Q LQ ++
Sbjct: 1089 QTVSLQEQNTTLQTQN 1104
Score = 35.0 bits (79), Expect = 0.56
Identities = 38/172 (22%), Positives = 79/172 (45%), Gaps = 11/172 (6%)
Query: 484 LQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEI 543
L+K L+SFK Q + K + L E E +N + L A ++ Q + +E+
Sbjct: 675 LKKTLDSFKNLTFQLESLEKE---NSQLDEE-NLELRRNVESLKCASMKMAQLQLENKEL 730
Query: 544 RRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKAR 603
+Q + G++ L + + E+S + Q Q +N + +Q L++
Sbjct: 731 ESEKEQL--KKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS---NKKIQQLESE 785
Query: 604 CEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQE 655
++L+++ TL +K L+E + ++ + ++ L+ +LEK ++Q E
Sbjct: 786 LQDLEMENQTL--QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE 835
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 48.1 bits (113), Expect = 6e-05
Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 19/176 (10%)
Query: 486 KLLESFKIQYLQFL-----AYTKTPQYKASLQELLGQEKEKNAQLLGA---AQQLLSHCQ 537
K LES K Q + L ++ KT + + S Q L + + L + QQL S Q
Sbjct: 728 KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Query: 538 AQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSL 597
+ E + L Q+ L+EL + + L + K + QL + +QLE++N+ LR Q
Sbjct: 788 DLEMENQTL-QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ-- 844
Query: 598 QLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQ 653
A ++ L+ + + L KE + L +I + C+ L+ ELEK ++
Sbjct: 845 ----AEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLK----ELEKENKE 892
Score = 43.9 bits (102), Expect = 0.001
Identities = 49/215 (22%), Positives = 101/215 (46%), Gaps = 30/215 (13%)
Query: 508 KASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGV--KALTYNDLI 565
KA ++ L + +EK QLL Q+L + + E++RL Q+ ++ L A Y D +
Sbjct: 257 KAKIRRLRQELEEKTEQLLDCKQEL----EQMEIELKRLQQENMNLLSDARSARMYRDEL 312
Query: 566 QAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATL-----SLEKLL 620
A +E + +L + + ++ R ++ KAR EEL+ D L LE L
Sbjct: 313 DALREKAVRVDKLESEVSRYKE-----RLHDIEFYKARVEELKEDNQVLLETKTMLEDQL 367
Query: 621 KEKQALKSQISEKQRHCLELQISI--VELEKSQRQQELLQLKSCVPPDDALSLHLRGKGA 678
+ +A ++ E ++ L+L+ + +E+E+ ++++ +L ++ ++L + K +
Sbjct: 368 EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM-----EENMTLEMAQKQS 422
Query: 679 LGRELEPDASRLHLELDCTKFSLPHLSSMSPELSM 713
+ LHL + + S S +P+ S+
Sbjct: 423 MDES-------LHLGWELEQISRTSELSEAPQKSL 450
Score = 38.9 bits (89), Expect = 0.039
Identities = 63/272 (23%), Positives = 117/272 (43%), Gaps = 26/272 (9%)
Query: 410 KRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQR 469
KR + + MN + R + + LDAL + V S Y+ V+
Sbjct: 289 KRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEE 348
Query: 470 HSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTP-QYKASLQEL----------LGQE 518
+ ++ T L+ LE + + + K Q KA L ++ + +
Sbjct: 349 LKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEEL 408
Query: 519 KEKNAQLLGAAQQLLS---HCQAQKEEIRRLFQQKLDELGVKALTY--NDLIQAQK-EIS 572
E+N L A +Q + H + E+I R +L E K+L + N+L ++ ++
Sbjct: 409 MEENMTLEMAQKQSMDESLHLGWELEQISRT--SELSEAPQKSLGHEVNELTSSRLLKLE 466
Query: 573 AHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLE-KLLKEKQALK---- 627
NQ L + E+L ++ G + ++LK E +L LE ++++EKQ+L+
Sbjct: 467 MENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Query: 628 -SQISEKQRHCLELQISIVELEKSQRQQELLQ 658
S+ K++ LE I + E S+RQ ++L+
Sbjct: 527 LSKDLMKEKAQLEKTIETLR-ENSERQIKILE 557
Score = 38.9 bits (89), Expect = 0.039
Identities = 47/212 (22%), Positives = 90/212 (42%), Gaps = 30/212 (14%)
Query: 508 KASLQELLGQEKEKNAQLLGAAQQL---LSHCQAQKEEIRRLFQQKLDELGVKALTYNDL 564
K +++ L KEK + A++L L H + + E L Q+K+ L + L
Sbjct: 610 KRQIKKELEHYKEKGER----AEELENELHHLEKENE----LLQKKITNLKITCEKIEAL 661
Query: 565 IQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQ 624
Q E+ N++L++ + + + + QL E QLD L L + ++ +
Sbjct: 662 EQENSELERENRKLKKTLD-------SFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Query: 625 ALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELE 684
++++ L+L+ +E EK Q ++ L LK+ + L + +G L+
Sbjct: 715 CASMKMAQ-----LQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQG-------LD 762
Query: 685 PDASRLHLELDCTKFSLPHLSSMSPELSMNGQ 716
+ RL L+ + + L S +L M Q
Sbjct: 763 IENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Score = 37.4 bits (85), Expect = 0.11
Identities = 45/195 (23%), Positives = 89/195 (45%), Gaps = 44/195 (22%)
Query: 503 KTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYN 562
KT Q L++L E EK +G ++ L H + ++ +L + KL+ K+L
Sbjct: 917 KTQQMNNDLEKLT-HELEK----IGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIK 971
Query: 563 D----LIQAQKEISA-HNQQLREQSEQLEQDNRALRGQ---------------------- 595
+ ++A+ E S +NQQLR++ + ++++ AL+ +
Sbjct: 972 EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWER 1031
Query: 596 -----SLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKS 650
+ +LLK + ++++ +L+ EKQALK+Q+ + + LQ I+ L++
Sbjct: 1032 ESQETTRELLKVKDRLIEVERNNATLQA---EKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Query: 651 ----QRQQELLQLKS 661
Q Q LQ ++
Sbjct: 1089 TVSLQEQNTTLQTQN 1103
Score = 35.0 bits (79), Expect = 0.56
Identities = 38/172 (22%), Positives = 79/172 (45%), Gaps = 11/172 (6%)
Query: 484 LQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEI 543
L+K L+SFK Q + K + L E E +N + L A ++ Q + +E+
Sbjct: 675 LKKTLDSFKNLTFQLESLEKE---NSQLDEE-NLELRRNVESLKCASMKMAQLQLENKEL 730
Query: 544 RRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKAR 603
+Q + G++ L + + E+S + Q Q +N + +Q L++
Sbjct: 731 ESEKEQL--KKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS---NKKIQQLESE 785
Query: 604 CEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQE 655
++L+++ TL +K L+E + ++ + ++ L+ +LEK ++Q E
Sbjct: 786 LQDLEMENQTL--QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE 835
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 48.1 bits (113), Expect = 6e-05
Identities = 100/406 (24%), Positives = 148/406 (36%), Gaps = 80/406 (19%)
Query: 935 AGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQP 994
+G S++ S++ + + SP+ L+P DE +GS ++ GSRS +P
Sbjct: 257 SGSSHSPSLSSHYSDSRSPSRLSPKHR----DEGRKTGSQRSS-GSRSPSPSG------- 304
Query: 995 RNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAG 1054
S SP S R G P S D PS P + + T
Sbjct: 305 -GSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSS-----PSPRVRDKAAAAAPTPPA 358
Query: 1055 SAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRA--LPS 1112
K+SPS + +P + G G+ RRR RR+R S S+ +P+RR P
Sbjct: 359 RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRR------SRSSASAPRRRGRRRPR 412
Query: 1113 VAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVP------YQDHDQPPVL 1166
A P GS +L+ S SS S + +P P + H
Sbjct: 413 PA----PPRGSSRSLSRARS-----------SSDSGSGRGAPGPGPEPGSERGHGGHGKR 457
Query: 1167 KKERP-------LSQTNGAH-----YSPLTSDEEPGSEDEP-SSARIERKIATISLE--- 1210
KERP S + GAH +S PG SS+R K + S E
Sbjct: 458 AKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP 517
Query: 1211 -----SKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPL---- 1261
S SP K L GR E + + ++SPI + DSP
Sbjct: 518 HSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIR----KRRRDSPSFMEP 573
Query: 1262 QASSALSQNSLFTFRPALEEP----SADAKLAAHPRKGFPGSLSGA 1303
+ ++ + + +RP+ S+D +H R PG G+
Sbjct: 574 RRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGS 619
Score = 33.5 bits (75), Expect = 1.6
Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 350 KSNAATPTKGPEGKVA-GPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAG 408
K+ AA PT GK + P AP G AG A ++ + R+ + + + G
Sbjct: 348 KAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRG 407
Query: 409 RKRGRP 414
R+R RP
Sbjct: 408 RRRPRP 413
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 47.8 bits (112), Expect = 8e-05
Identities = 95/398 (23%), Positives = 139/398 (34%), Gaps = 88/398 (22%)
Query: 863 TSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANA 922
T LP P ++P + P P+A P+R P+P +P PS + A
Sbjct: 1087 TPLPQKDPAQPLEPKRPPPPRPVAP---PTR-------PAPPQRPPPPSGRSQPSPQAGL 1136
Query: 923 HGAGSRSLALAPAGFSYAG-SVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSR 981
G G PAG+S A ++ + +P S + ES S S + +
Sbjct: 1137 AGPG-------PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTF 1189
Query: 982 SSTPQHPLLLAQPRNSLP-------------ASPAHQLSSSPRLGGAAQGPLPEASKGDL 1028
P P P++SLP A+P Q P L Q P S L
Sbjct: 1190 LPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSL 1249
Query: 1029 PSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGR 1088
PS++ S P+ + T G K+ K P + S Q
Sbjct: 1250 PSEAS-SQPQVK---------TNGISDGKRESPLKIDPFEDLSFNLLAVSKAQ------- 1292
Query: 1089 RKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPET 1148
LS SP P L PS + N+ S VS + I A S +
Sbjct: 1293 ----------LSVQTSPV--PTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQE 1340
Query: 1149 SLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATIS 1208
+++SSP P+ L + P S A PG+ P A+ E AT S
Sbjct: 1341 NMRSSPNPFITG-----LTRTNPFSDRTAA----------PGN---PFRAKSEESEAT-S 1381
Query: 1209 LESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFS 1246
SK P T+ P P+ +P+ +K +++ S
Sbjct: 1382 WFSKEEPVTI---------SPFPSLQPLGHNKSRASSS 1410
Score = 42.4 bits (98), Expect = 0.004
Identities = 64/262 (24%), Positives = 94/262 (35%), Gaps = 22/262 (8%)
Query: 962 PATLDESSSSGSLFATVGSRSSTP-QHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL 1020
P L SSSSG + S ++P Q P + P SLP P+ S +P A P+
Sbjct: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPI 1081
Query: 1021 PEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHG 1080
LP DP + + A + +P + P S R P G
Sbjct: 1082 DAQPATPLPQ----KDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP--PSGRSQPSPQAG 1135
Query: 1081 QDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSN-INQPLE 1139
A P + +S + + AG T S S + S S + +PL+
Sbjct: 1136 LAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLK 1195
Query: 1140 ITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSAR 1199
A P++SL P P Q Q P++ P+ Q S +P E P
Sbjct: 1196 PQAAFPPQSSL---PPPAQ-RLQEPLVPVAAPMPQ----------SGPQPNLETPPQPPP 1241
Query: 1200 IERKIATISLESKSPPKTLENG 1221
R ++ E+ S P+ NG
Sbjct: 1242 RSRSSHSLPSEASSQPQVKTNG 1263
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 47.8 bits (112), Expect = 8e-05
Identities = 77/355 (21%), Positives = 126/355 (35%), Gaps = 35/355 (9%)
Query: 979 GSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPE 1038
G+RS T P +QP+ A P GG P ++ D P S + P+
Sbjct: 224 GTRSGTRPGPF--SQPKQQHQQQLAEDAKDVP--GGGPSSSAPAGAEADGPKASPEARPQ 279
Query: 1039 SEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPS 1098
K R+ + A P+ + +P A P+ R ++
Sbjct: 280 IPTKPRVPGKLQELASP----PAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAG 335
Query: 1099 LSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQ 1158
S+ V+ + LP +P G+P + P IT + + E K +P+P
Sbjct: 336 SSSLVNGRLHELP-----VPKPRGTPKPSEGTPAPRKDPPWITLVQA-EPKKKPAPLPPS 389
Query: 1159 DHDQPPV-------------LKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIA 1205
PP + + P + Y+P +EE E+ P++ + A
Sbjct: 390 SSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPA 449
Query: 1206 TISLESKSPPKTLENGGGLAGR-----KPAPAGEPVNSSKWKSTFSPISDIGLAKSADSP 1260
ES PK+L G+ K PA ++S S +S + SP
Sbjct: 450 LGHPEST--PKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSP 507
Query: 1261 -LQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPAN 1314
L S S+++ T L EP A K ++ P PG+ LS ++ A+
Sbjct: 508 ALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLAS 562
Score = 43.5 bits (101), Expect = 0.002
Identities = 101/423 (23%), Positives = 146/423 (34%), Gaps = 52/423 (12%)
Query: 718 AGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPA 777
AG E G + P ++ P P + + P+ P K S P +P
Sbjct: 263 AGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTP-----APP 317
Query: 778 KIVLRRHLSQDHTVPGRPAASELHSRAEHT---KENGLPYQSPSVPGSMKLSP------- 827
R L Q++ V ++S ++ R K G P S P K P
Sbjct: 318 TPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQA 377
Query: 828 ---QDPRPL----SPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLP 880
+ P PL SPG + G E A S + S P + P + +K
Sbjct: 378 EPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYN-PFEEEEEDKEE 436
Query: 881 VSIPLASVVLPSRAERARSTPSPVLQPR---DPSSTLEKQIGANAHGAGSRSLALAPAGF 937
+ S+ STP L P P+S+ + + + LAL +
Sbjct: 437 EAPAAPSLATSPALGHPESTPKS-LHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRL 495
Query: 938 SYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRS-STPQHPLLLAQPRN 996
S++ P S TP PA ES SS S T G+ P P ++P
Sbjct: 496 SHS-----------EPPSATPS--PALSVESLSSESASQTAGAELLEPPAVPKSSSEPAV 542
Query: 997 SLPASPAHQLSSSPRLGGAAQGPL--------PEASKGDLPSDSGFSDPESEAKRRIVFT 1048
P +P + +S S A+ G L P+AS G P G S P+ AK T
Sbjct: 543 HAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQ-PAKPCSGAT 601
Query: 1049 ITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRR 1108
T +SP SP ++S + S ++ R AS T + G P R
Sbjct: 602 PTPLLLVGDRSPVP--SPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRP 659
Query: 1109 ALP 1111
P
Sbjct: 660 PAP 662
Score = 32.0 bits (71), Expect = 4.7
Identities = 103/473 (21%), Positives = 158/473 (33%), Gaps = 70/473 (14%)
Query: 782 RRHLSQD-HTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQL 840
++ L++D VPG +S + AE P P +P +P PG LQ
Sbjct: 242 QQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIP---------TKPRVPGKLQE 292
Query: 841 AGEKSSEKGLRERAYGSSGELITSLPISI-PLSTVQPNKLPVSIPLASVVLPSRAERARS 899
S G A + E T P + P S++Q L +S+V R
Sbjct: 293 LA--SPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLV------NGRL 344
Query: 900 TPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPG 959
PV +PR E G A + L A + + G P+ +
Sbjct: 345 HELPVPKPRGTPKPSE---GTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQ 401
Query: 960 AEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGP 1019
E +E + + S S P +P + A A L++SP LG
Sbjct: 402 VENGGTEEVAQP----SPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGH----- 452
Query: 1020 LPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSH 1079
PE++ L G + P S K T A ++PS+ L AS P
Sbjct: 453 -PESTPKSLHPWYGIT-PTSSPK--------TKKRPAPRAPSASPLALHASRLSHSEPPS 502
Query: 1080 GQDSRRRGRRKRAS------AGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSN 1133
S +S AG L PK + P+V T + L+ NS +++
Sbjct: 503 ATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLAS 562
Query: 1134 INQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSP--LTSDEEPGS 1191
+ +E P+ S +P + +P +GA +P L D P
Sbjct: 563 SGELVEPRVEQMPQASPGLAP-------RTRGSSGPQPAKPCSGATPTPLLLVGDRSPVP 615
Query: 1192 EDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKST 1244
SS +++ + K P RKP+PA P K +
Sbjct: 616 SPGSSSPQLQ-----VKSSCKENP---------FNRKPSPAASPATKKATKGS 654
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 47.4 bits (111), Expect = 1e-04
Identities = 98/423 (23%), Positives = 146/423 (34%), Gaps = 96/423 (22%)
Query: 863 TSLPISIPLSTVQPNKLPVSIPLASVVLPSRAER------ARST-------------PSP 903
T LP P ++P + P P+A P+ +R ARS PSP
Sbjct: 1131 TPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSP 1190
Query: 904 VLQ------PRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAG-SVAISGALAGSPASL 956
+ P+ P +T + IG + + PAG+S A ++ + +P S
Sbjct: 1191 GVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSH 1250
Query: 957 TPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLP-------------ASPA 1003
+ ES S S + + P P P++SLP A+P
Sbjct: 1251 ARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPM 1310
Query: 1004 HQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSK 1063
Q P L Q P S LPS++ S P+ + T G K+ K
Sbjct: 1311 PQSGPQPNLETPPQPPPRSRSSHSLPSEAS-SQPQVK---------TNGISDGKRESPLK 1360
Query: 1064 HSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGS 1123
P + S Q LS SP P L PS +
Sbjct: 1361 IDPFEDLSFNLLAVSKAQ-----------------LSVQTSPV--PTPDPKRLIQLPSAT 1401
Query: 1124 PLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPL 1183
N+ S VS + I A S + +++SSP P+ L + P S A
Sbjct: 1402 QSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITG-----LTRTNPFSDRTAA----- 1451
Query: 1184 TSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKS 1243
PG+ P A+ E AT S SK P T+ P P+ +P+ +K ++
Sbjct: 1452 -----PGN---PFRAKSEESEAT-SWFSKEEPVTI---------SPFPSLQPLGHNKSRA 1493
Query: 1244 TFS 1246
+ S
Sbjct: 1494 SSS 1496
Score = 37.7 bits (86), Expect = 0.086
Identities = 67/288 (23%), Positives = 99/288 (34%), Gaps = 32/288 (11%)
Query: 962 PATLDESSSSGSLFATVGSRSSTP-QHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPL 1020
P L SSSSG + S ++P Q P + P SLP P+ S +P A P+
Sbjct: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPI 1125
Query: 1021 PEASKGDLPSDSGFS--DPESEAKRRIVFTITTGAGSAKQSPSS---KHSPLTASARGDC 1075
LP +P+ R V T A + P S +P G
Sbjct: 1126 DAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIG 1185
Query: 1076 VPSHGQDSRRR-------GRRKRASAGTPSLS----------AGVSPKRRALPSVAGLFT 1118
P +RR G ++ + G S AG S R +P AG+ +
Sbjct: 1186 APPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVIS 1245
Query: 1119 QP-SGSPLNLNSMVSNINQPLEITAISS---PETSLKSSPVPYQDHDQPPVLKKERPLSQ 1174
P S + + + T+ S PE + P Q PP + + PL
Sbjct: 1246 APQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVP 1305
Query: 1175 TNGAHYSPL-TSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENG 1221
+P+ S +P E P R ++ E+ S P+ NG
Sbjct: 1306 V----AAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNG 1349
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 47.0 bits (110), Expect = 1e-04
Identities = 75/367 (20%), Positives = 145/367 (39%), Gaps = 44/367 (11%)
Query: 322 LENYFSSLKNPKLREEQEAAR-RRQQRESKSNAATPTKGPEGKVA----GPADAPMDSGA 376
+ + SSL+N + + E R +R+ RE++S+ T+ G + P D A
Sbjct: 476 MRHLISSLQNHNHQLKGEVLRYKRKLREAQSDL-NKTRLRSGSALLQSQSSTEDPKDEPA 534
Query: 377 EEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTALDAL 436
E + + S SKA ++ N+ K +R R ++ ER+ +K +
Sbjct: 535 ELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREK 594
Query: 437 HAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFKIQYL 496
S+ S +D + H ++ L+K ES K L
Sbjct: 595 QKLKESEKERDSAKDKEKGKHD---------DGRKKEAEIIKQLKIELKKAQESQKEMKL 645
Query: 497 QFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGV 556
Y P+ + +L+ EK+ A+L Q+L +K+E +++ + D L
Sbjct: 646 LLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADE--DALRK 703
Query: 557 KALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRA---LRGQSLQLLKARCEELQLDWAT 613
+ QK+++ Q+ +++ +A ++ Q+++L++ E+ ++
Sbjct: 704 IRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKL 763
Query: 614 LS-------LEKLLKEKQ--------ALKSQIS---------EKQRHCLELQISIVELEK 649
+S + KLLKE++ LK+Q+ E++ H L+ I E E
Sbjct: 764 MSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKEL 823
Query: 650 SQRQQEL 656
R Q L
Sbjct: 824 GLRTQAL 830
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 46.6 bits (109), Expect = 2e-04
Identities = 79/341 (23%), Positives = 127/341 (37%), Gaps = 42/341 (12%)
Query: 328 SLKNPKLREEQEAARRRQQRESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVK 387
S NPK R+ AR R SKS P G + P S KA A V+
Sbjct: 315 SPSNPKARQP---ARSRLWLPSKSLPHLP-----GTPRPTSSLPPGS----VKAAPAQVR 362
Query: 388 KPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAAS 447
PSP R K K P+K+ K + L + TV + +
Sbjct: 363 PPSPGNIRPVKREVKVEPEKKDPEKEPQKV----ANEPSLKGRAPLVKVEEATVEERTPA 418
Query: 448 SPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQY 507
P+ +P +P P V PTP + A + T
Sbjct: 419 EPEVGPAAPAMAPAPASAPAPASAPAPAPV-PTPAMVS--------------APSSTVNA 463
Query: 508 KASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRR-----LFQQKLDELGVKALTYN 562
AS++ G + A L A ++ L+ Q +KEE R L +QK +EL +
Sbjct: 464 SASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEER 523
Query: 563 DLIQAQKEISAHNQQLREQSEQLEQ--DNRALRGQSLQLLKARCEELQLDWATLSLEKLL 620
+ ++ +Q RE+ EQL++ + RALR + +A + Q + E+
Sbjct: 524 TTRREEESRRLEAEQAREKEEQLQRQAEERALRERE----EAERAQRQKEEEARVREEAE 579
Query: 621 KEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKS 661
+ +Q + +++ LE + + E+ K R+ E K+
Sbjct: 580 RVRQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKT 620
Score = 32.3 bits (72), Expect = 3.6
Identities = 88/415 (21%), Positives = 164/415 (39%), Gaps = 58/415 (13%)
Query: 541 EEIRRLFQQKLDELGVKALTYNDLIQAQKEISA---HNQQLREQSEQLEQDNRALRGQSL 597
++ +RL +++ +E K L +++ ++E A + + L E+ ++LE+ + +
Sbjct: 64 DDRQRLARERREERE-KQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRA 122
Query: 598 QLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRH-------CLELQISIVELEKS 650
+ + R + L+ D + + + +SQ KQ+H L SI +
Sbjct: 123 AVEEKRRQRLEED---KERHEAVVRRTMERSQ-KPKQKHNRWSWGGSLHGSPSIHSADPD 178
Query: 651 QRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCTKFSLPH------- 703
+R + L V P +S L A PD +R L+L + S+ +
Sbjct: 179 RRSVSTMNLSKYVDP--VISKRLSSSSATLLN-SPDRAR-RLQLSPWESSVVNRLLTPTH 234
Query: 704 --LSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLE 761
L+ +++G+AA C + P ++ + +D+ + TP G R
Sbjct: 235 SFLARSKSTAALSGEAAS---CSPIIMPYKAAHS----RNSMDRPKLFVTPPE-GSSRRR 286
Query: 762 KLSGLAAPDYTRLSPAKIVL----RRHLSQDHTVPGRPAASELHSRAEHTKE-NGLPYQS 816
+ G A+ R + L RR +S + +PA S L ++ G P +
Sbjct: 287 IIHGTASYKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPT 346
Query: 817 PSVP-GSMKLSPQDPRPLSPGALQLA------------GEKSSEKGLRERAYGSSGELIT 863
S+P GS+K +P RP SPG ++ EK +K E + L+
Sbjct: 347 SSLPPGSVKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVK 406
Query: 864 SLPISIPLST-VQPNKLPVSIPLASVVLPSRAERARSTPSPVLQP---RDPSSTL 914
++ T +P P + +A + A + P+PV P PSST+
Sbjct: 407 VEEATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTV 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,382,159
Number of Sequences: 37866
Number of extensions: 3633204
Number of successful extensions: 19811
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 1159
Number of HSP's that attempted gapping in prelim test: 15985
Number of HSP's gapped (non-prelim): 4704
length of query: 1537
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1422
effective length of database: 13,892,928
effective search space: 19755743616
effective search space used: 19755743616
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.