Guide to the Human Genome
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Search of human proteins with 11497612

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform
b precursor [Homo sapiens]
         (844 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...  1715   0.0  
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...  1623   0.0  
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform...  1615   0.0  
gi|40255245 G protein-coupled receptor 51 [Homo sapiens]              477   e-134
gi|23308585 G protein-coupled receptor 156 [Homo sapiens]             119   2e-26
gi|4580422 natriuretic peptide receptor B precursor [Homo sapiens]     65   2e-10
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]           65   3e-10
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur...    60   1e-08
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur...    60   1e-08
gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]            59   2e-08
gi|32528268 glutamate receptor, metabotropic 7 isoform b precurs...    55   2e-07
gi|4504147 glutamate receptor, metabotropic 7 isoform a precurso...    55   2e-07
gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens]          55   2e-07
gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]          55   2e-07
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur...    54   8e-07
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso...    54   8e-07
gi|167830411 natriuretic peptide receptor 1 [Homo sapiens]             54   8e-07
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ...    53   1e-06
gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo ...    52   2e-06
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs...    52   2e-06
gi|37577159 calcium-sensing receptor [Homo sapiens]                    50   7e-06
gi|4505441 natriuretic peptide receptor C/guanylate cyclase C (a...    49   1e-05
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre...    49   1e-05
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr...    49   1e-05
gi|93352554 GPR158-like 1 [Homo sapiens]                               48   4e-05
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]           45   3e-04
gi|112807234 G protein-coupled receptor, family C, group 6, memb...    45   4e-04
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s...    43   0.001
gi|187761324 shootin1 isoform a [Homo sapiens]                         42   0.002
gi|50511340 shootin1 isoform b [Homo sapiens]                          42   0.002

>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
           precursor [Homo sapiens]
          Length = 844

 Score = 1715 bits (4442), Expect = 0.0
 Identities = 844/844 (100%), Positives = 844/844 (100%)

Query: 1   MGPGAPFARVGWPLPLLVVMAAGVAPVWASHSPHLPRPHSRVPPHPSSERRAVYIGALFP 60
           MGPGAPFARVGWPLPLLVVMAAGVAPVWASHSPHLPRPHSRVPPHPSSERRAVYIGALFP
Sbjct: 1   MGPGAPFARVGWPLPLLVVMAAGVAPVWASHSPHLPRPHSRVPPHPSSERRAVYIGALFP 60

Query: 61  MSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDP 120
           MSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDP
Sbjct: 61  MSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDP 120

Query: 121 IKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTR 180
           IKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTR
Sbjct: 121 IKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTR 180

Query: 181 VKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQ 240
           VKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQ
Sbjct: 181 VKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQ 240

Query: 241 DARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTE 300
           DARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTE
Sbjct: 241 DARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTE 300

Query: 301 AVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWAL 360
           AVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWAL
Sbjct: 301 AVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWAL 360

Query: 361 ALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWT 420
           ALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWT
Sbjct: 361 ALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWT 420

Query: 421 LIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSV 480
           LIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSV
Sbjct: 421 LIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSV 480

Query: 481 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 540
           LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN
Sbjct: 481 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 540

Query: 541 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 600
           QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL
Sbjct: 541 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 600

Query: 601 VGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYK 660
           VGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYK
Sbjct: 601 VGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYK 660

Query: 661 GLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFA 720
           GLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFA
Sbjct: 661 GLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFA 720

Query: 721 SLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRE 780
           SLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRE
Sbjct: 721 SLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRE 780

Query: 781 LEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVH 840
           LEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVH
Sbjct: 781 LEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVH 840

Query: 841 LLYK 844
           LLYK
Sbjct: 841 LLYK 844


>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
           precursor [Homo sapiens]
          Length = 961

 Score = 1623 bits (4204), Expect = 0.0
 Identities = 802/809 (99%), Positives = 804/809 (99%)

Query: 36  PRPHSRVPPHPSSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELK 95
           P+PH +V   P SERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELK
Sbjct: 153 PKPHCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELK 212

Query: 96  LIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSP 155
           LIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSP
Sbjct: 213 LIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSP 272

Query: 156 ALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE 215
           ALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE
Sbjct: 273 ALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE 332

Query: 216 AGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFL 275
           AGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFL
Sbjct: 333 AGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFL 392

Query: 276 IGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTK 335
           IGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTK
Sbjct: 393 IGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTK 452

Query: 336 RLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRA 395
           RLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRA
Sbjct: 453 RLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRA 512

Query: 396 MNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGS 455
           MNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGS
Sbjct: 513 MNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGS 572

Query: 456 PPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNL 515
           PPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNL
Sbjct: 573 PPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNL 632

Query: 516 TAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVF 575
           TAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVF
Sbjct: 633 TAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVF 692

Query: 576 TKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDV 635
           TKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDV
Sbjct: 693 TKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDV 752

Query: 636 SILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNV 695
           SILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNV
Sbjct: 753 SILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNV 812

Query: 696 AVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQD 755
           AVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQD
Sbjct: 813 AVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQD 872

Query: 756 TMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPP 815
           TMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPP
Sbjct: 873 TMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPP 932

Query: 816 EPSGGLPRGPPEPPDRLSCDGSRVHLLYK 844
           EPSGGLPRGPPEPPDRLSCDGSRVHLLYK
Sbjct: 933 EPSGGLPRGPPEPPDRLSCDGSRVHLLYK 961


>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
           precursor [Homo sapiens]
          Length = 899

 Score = 1615 bits (4182), Expect = 0.0
 Identities = 798/799 (99%), Positives = 798/799 (99%)

Query: 46  PSSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDP 105
           P SERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDP
Sbjct: 101 PHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDP 160

Query: 106 GQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPT 165
           GQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPT
Sbjct: 161 GQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPT 220

Query: 166 FFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQS 225
           FFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQS
Sbjct: 221 FFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQS 280

Query: 226 FFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFK 285
           FFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFK
Sbjct: 281 FFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFK 340

Query: 286 IYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETG 345
           IYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETG
Sbjct: 341 IYDPSINCTVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETG 400

Query: 346 GFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVS 405
           GFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVS
Sbjct: 401 GFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVS 460

Query: 406 GHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIK 465
           GHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIK
Sbjct: 461 GHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIK 520

Query: 466 TFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALA 525
           TFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALA
Sbjct: 521 TFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALA 580

Query: 526 AVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWR 585
           AVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWR
Sbjct: 581 AVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWR 640

Query: 586 KTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCS 645
           KTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCS
Sbjct: 641 KTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCS 700

Query: 646 SRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPV 705
           SRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPV
Sbjct: 701 SRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPV 760

Query: 706 TMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNN 765
           TMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNN
Sbjct: 761 TMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNN 820

Query: 766 NEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGP 825
           NEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGP
Sbjct: 821 NEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGP 880

Query: 826 PEPPDRLSCDGSRVHLLYK 844
           PEPPDRLSCDGSRVHLLYK
Sbjct: 881 PEPPDRLSCDGSRVHLLYK 899


>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
          Length = 941

 Score =  477 bits (1228), Expect = e-134
 Identities = 286/811 (35%), Positives = 448/811 (55%), Gaps = 46/811 (5%)

Query: 14  LPLLVVMAAGVAPVWASHSPHLPRPHSRVPPHPSSERRAVYIGALFPMS---GGWPGGQA 70
           LPLL+ +A G A  WA  +P   RP    PP        + I  L P++        G+ 
Sbjct: 29  LPLLLPLAPG-AWGWARGAP---RPPPSSPP--------LSIMGLMPLTKEVAKGSIGRG 76

Query: 71  CQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPG-C 129
             PAVE+A+E + +   +L  Y L L  +D++CD  +  K  Y+ +   P  +++  G C
Sbjct: 77  VLPAVELAIEQIRNE-SLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVC 135

Query: 130 SSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 189
            SV++++AE+ + WNL+ LS+ +++P L++++++P FFRT PS    NP  +KL + + W
Sbjct: 136 PSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQW 195

Query: 190 KKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLF 249
           K++ T+ Q  + F+   +DL   +    IEI+  +SF +DP   VK LK  D RII+G F
Sbjct: 196 KRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQF 255

Query: 250 YETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSIN---CTVDEMTEAVEGHI 306
            +  A KVFC  Y+E ++G KY W + GWY  +W++      N   C    +  A+EG+I
Sbjct: 256 DQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYI 315

Query: 307 TTEIVMLNPANTRSISNMTSQEFVEKLT-KRLKRHPEETGGFQEAPLAYDAIWALALALN 365
             +   L+    ++IS  T Q++  +   KR    P +  G+     AYD IW +A  L 
Sbjct: 316 GVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGY-----AYDGIWVIAKTLQ 370

Query: 366 KTSGGGGRSG--VRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE 423
           +       S    R++DFNY + T+   I  AMN ++F GV+G VVF  +G RM      
Sbjct: 371 RAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVF-RNGERMGTIKFT 429

Query: 424 QLQGGSYKKIGYYDSTKDDLSW-SKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLS 482
           Q Q     K+G Y++  D L   + T ++ G  PP D+T++++  R +S  L+  +S L+
Sbjct: 430 QFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALT 489

Query: 483 SLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQF 542
            LG+++A   L FNI N + + I+ S P +NNL  +G  L+ A++F  GLDG  +    F
Sbjct: 490 ILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTF 549

Query: 543 PFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVG 602
             +C  R W+L +G++  +G+MF K W VH +F   + KK   K ++  KL   VG ++ 
Sbjct: 550 ETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKK---KIIKDQKLLVIVGGMLL 606

Query: 603 MDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGL 662
           +D+  L  WQ VDPL RT+E ++ E      D+SI P LEHC +  M  WLGI Y YKGL
Sbjct: 607 IDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGL 666

Query: 663 LLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASL 722
           L+L G FLA+ET++VS   +ND + +GM++YNV ++C+I A V+ +   Q +  F   +L
Sbjct: 667 LMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVAL 726

Query: 723 AIVFSSYITLVVLFVPKMRRLITRGE----------WQSEAQDTMKTGSS-TNNNEEEKS 771
            I+F S ITL ++FVPK+  L T  +           Q++ ++  KT +S T+ N+   S
Sbjct: 727 VIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTS 786

Query: 772 RL--LEKENRELEKIIAEKEERVSELRHQLQ 800
           RL  L+ EN  L   I E ++ + E+  QLQ
Sbjct: 787 RLEGLQSENHRLRMKITELDKDLEEVTMQLQ 817


>gi|23308585 G protein-coupled receptor 156 [Homo sapiens]
          Length = 814

 Score =  119 bits (297), Expect = 2e-26
 Identities = 100/386 (25%), Positives = 176/386 (45%), Gaps = 14/386 (3%)

Query: 465 KTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLAL 524
           KT   LS  L   V    S G++L +  L+F I+    R ++ S PNLN +T +G  L  
Sbjct: 40  KTISSLSPVLLGIVWTFLSCGLLLILFFLAFTIHCRKNRIVKMSSPNLNIVTLLGSCLTY 99

Query: 525 AAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEW 584
           ++ +  G+    +G +    + Q RL +L +G SL +G +  K W ++ VFT++   K  
Sbjct: 100 SSAYLFGIQDVLVGSSMETLI-QTRLSMLCIGTSLVFGPILGKSWRLYKVFTQRVPDK-- 156

Query: 585 RKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEH- 643
           R  ++  +L   V  L+  DV+ L  W + DP+ + ++  +        DVS      H 
Sbjct: 157 RVIIKDLQLLGLVAALLMADVILLMTWVLTDPI-QCLQILSVSMTVTGKDVSCTSTSTHF 215

Query: 644 CSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITA 703
           C+SR  + W+ + +G KGLLLL G +LA  T  VS+  +N    + + +  + +   +  
Sbjct: 216 CASRYSDVWIALIWGCKGLLLLYGAYLAGLTGHVSSPPVNQSLTIMVGVNLLVLAAGLLF 275

Query: 704 PVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST 763
            VT  L S  +  F   S  I   +      +F+P++++     E     +   K  S+ 
Sbjct: 276 VVTRYLHSWPNLVFGLTSGGIFVCTTTINCFIFIPQLKQWKAFEEENQTIRRMAKYFSTP 335

Query: 764 NNN-----EEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQ--LRSRRHPPTPPE 816
           N +      EE++     E   +E+++ EK   +  L+ Q+ + ++  +R      T   
Sbjct: 336 NKSFHTQYGEEENCHPRGEKSSMERLLTEKNAVIESLQEQVNNAKEKIVRLMSAECTYDL 395

Query: 817 PSGGLPRGPPEPPDRLSCDGSRVHLL 842
           P G  P  P   P++     + VH L
Sbjct: 396 PEGAAP--PASSPNKDVQAVASVHTL 419


>gi|4580422 natriuretic peptide receptor B precursor [Homo sapiens]
          Length = 1047

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 94/421 (22%), Positives = 164/421 (38%), Gaps = 66/421 (15%)

Query: 73  PAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYEL------LYNDPIKIILM 126
           PAV +A+E +     +    +L+ +  + +   G  ++YL  L      LY+DP  ++L 
Sbjct: 47  PAVALAVEALGRALPV----DLRFVSSELE---GACSEYLAPLSAVDLKLYHDP-DLLLG 98

Query: 127 PGCSSVSTLVAEAARMWNLIVLSYGSSSPALS-NRQRFPTFFRTHPSATLHNPTRVKLFE 185
           PGC   +  VA  A  W L +L+ G+ +   S     + T  RT PSA       V L  
Sbjct: 99  PGCVYPAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHG 158

Query: 186 KWGWKKIATI-----QQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVP--VKNLK 238
            + W   A +     +        T++ + E ++ + + +   Q +  +P  P    +  
Sbjct: 159 HFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQ-HQVYAREPGGPEQATHFI 217

Query: 239 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADN-----WFKIYDPSINC 293
           R + RI+          ++  +  +E L    YV+F +  + ++           P  + 
Sbjct: 218 RANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDN 277

Query: 294 TVDEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAP-- 351
              E  +A+     T +V+      R   N   QEF  +L  R +    E  G +  P  
Sbjct: 278 RTREQAQALREAFQTVLVI----TYREPPNPEYQEFQNRLLIRAR----EDFGVELGPSL 329

Query: 352 ------LAYDAIWALALALNKT--SGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEG 403
                   YD I   A  LN+T   GG    G+R              I   M    + G
Sbjct: 330 MNLIAGCFYDGILLYAEVLNETIQEGGTREDGLR--------------IVEKMQGRRYHG 375

Query: 404 VSGHVVFDASGSR----MAWTLIEQLQGGSYKKIGYYDSTKDDLSWS-KTDKWIGGSPPA 458
           V+G VV D +  R    + W +   L  G ++   +Y   +  + W+ +   W+ G+PP+
Sbjct: 376 VTGLVVMDKNNDRETDFVLWAM-GDLDSGDFQPAAHYSGAEKQIWWTGRPIPWVKGAPPS 434

Query: 459 D 459
           D
Sbjct: 435 D 435


>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
          Length = 912

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 10/198 (5%)

Query: 546 CQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDV 605
           C  R   LGLG S+ Y ++ TK   ++ +F + +      + + P    A    L+ + +
Sbjct: 652 CSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQL 711

Query: 606 LTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLL 665
           L + +W +VDP H  ++     + +  +D      +  C    ++  L    GY  LL++
Sbjct: 712 LGICVWFVVDPSHSVVDF----QDQRTLDPRFARGVLKCDISDLS--LICLLGYSMLLMV 765

Query: 666 LGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAF---AFASL 722
                A +T+ V  E  N+ + +G  +Y   ++ L   P+    S   D  +      ++
Sbjct: 766 TCTVYAIKTRGV-PETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTV 824

Query: 723 AIVFSSYITLVVLFVPKM 740
           ++  S+ ++L +L++PK+
Sbjct: 825 SVSLSASVSLGMLYMPKV 842



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 76/343 (22%), Positives = 143/343 (41%), Gaps = 61/343 (17%)

Query: 10  VGW---PLPLLVVMAAGVAPVWASHSPHLPRPHSRVPPHPSSER--RAVYIGALFPMSGG 64
           +GW    LPL ++++  +   W   S   P+ H    PH +S R    + +G LFP+ G 
Sbjct: 7   LGWWWARLPLCLLLS--LYGPWMPSSLGKPKGH----PHMNSIRIDGDITLGGLFPVHGR 60

Query: 65  WPGGQACQP-----------AVEMALEDVNSRRDILPDYEL--KLIHHDSKCDPG--QAT 109
              G+ C             A+  AL+ +N+  D+LP+  L  +++   S+      Q+ 
Sbjct: 61  GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL 120

Query: 110 KYLYELLYND----------------PIKIILMPGCS--SVSTLVAEAARMWNLIVLSYG 151
            ++  L+  D                P +++ + G S  SVS +VA   R++ +  +SY 
Sbjct: 121 TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA 180

Query: 152 SSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEE 211
           S++P LS+  R+  F R  PS T      V +     W  ++T+        S ++   +
Sbjct: 181 STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ 240

Query: 212 RVKEAG-------IEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKE 264
           + +E G       ++I           +  + L+  +AR ++    E + R+V     + 
Sbjct: 241 KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA 300

Query: 265 RLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHIT 307
              G    +F +G  +D+W     P ++     + E  EG +T
Sbjct: 301 NQTGH---FFWMG--SDSWGSKIAPVLH-----LEEVAEGAVT 333


>gi|187960069 glutamate receptor, metabotropic 8 isoform b precursor
           [Homo sapiens]
          Length = 908

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 51/242 (21%), Positives = 103/242 (42%), Gaps = 22/242 (9%)

Query: 545 VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD 604
           +C  R   LGLG    Y ++ TK   +H +F + ++     K + P         L+ + 
Sbjct: 647 ICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQ 706

Query: 605 VLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGY 659
           +L + +W +VDP H  I+     T   E+ +  +   I      CS            GY
Sbjct: 707 LLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICS-----------LGY 755

Query: 660 KGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAF-- 717
             LL++     A +T+ V  E  N+ + +G  +Y   ++ L   P+    +   +  +  
Sbjct: 756 SILLMVTCTVYAIKTRGV-PETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQ 814

Query: 718 -AFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEK 776
               ++++  S+ ++L +L++PK+  +I   E     Q   ++  +       +S+L++K
Sbjct: 815 TTTLTVSMSLSASVSLGMLYMPKVYIIIFHPE--QNVQKRKRSFKAVVTAATMQSKLIQK 872

Query: 777 EN 778
            N
Sbjct: 873 GN 874



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 70/319 (21%), Positives = 122/319 (38%), Gaps = 62/319 (19%)

Query: 35  LPRPHSRVPPHPSSERRAVYIGALFPMSGGWPGGQACQP-----------AVEMALEDVN 83
           + R HS+   H       + +G LFP+      G  C             A+  A++ +N
Sbjct: 28  MQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQIN 87

Query: 84  SRRDILPDYEL-----------------------KLIHHDS---KCDPGQATKYLYELLY 117
              D+L +  L                        LI  D+   KC  G         ++
Sbjct: 88  KDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPP------IF 141

Query: 118 NDPIKI--ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATL 175
             P KI  ++    SSVS +VA   R++ +  +SY S++P LS+  R+  F R  P  + 
Sbjct: 142 TKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY 201

Query: 176 HNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE-AGIEITFRQSFFSDP---- 230
                V +    GW  ++T+        S ++   +  +E  G+ I   Q    +P    
Sbjct: 202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGE 261

Query: 231 --AVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYD 288
              +  + L+  +AR ++    E + R++  E  K+      ++W  IG  +D+W     
Sbjct: 262 FEKIIKRLLETPNARAVIMFANEDDIRRIL-EAAKKLNQSGHFLW--IG--SDSWGSKIA 316

Query: 289 PSINCTVDEMTEAVEGHIT 307
           P     V +  E  EG +T
Sbjct: 317 P-----VYQQEEIAEGAVT 330


>gi|187960067 glutamate receptor, metabotropic 8 isoform a precursor
           [Homo sapiens]
          Length = 908

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 51/242 (21%), Positives = 103/242 (42%), Gaps = 22/242 (9%)

Query: 545 VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD 604
           +C  R   LGLG    Y ++ TK   +H +F + ++     K + P         L+ + 
Sbjct: 647 ICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQ 706

Query: 605 VLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGY 659
           +L + +W +VDP H  I+     T   E+ +  +   I      CS            GY
Sbjct: 707 LLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICS-----------LGY 755

Query: 660 KGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAF-- 717
             LL++     A +T+ V  E  N+ + +G  +Y   ++ L   P+    +   +  +  
Sbjct: 756 SILLMVTCTVYAIKTRGV-PETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQ 814

Query: 718 -AFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEK 776
               ++++  S+ ++L +L++PK+  +I   E     Q   ++  +       +S+L++K
Sbjct: 815 TTTLTVSMSLSASVSLGMLYMPKVYIIIFHPE--QNVQKRKRSFKAVVTAATMQSKLIQK 872

Query: 777 EN 778
            N
Sbjct: 873 GN 874



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 70/319 (21%), Positives = 122/319 (38%), Gaps = 62/319 (19%)

Query: 35  LPRPHSRVPPHPSSERRAVYIGALFPMSGGWPGGQACQP-----------AVEMALEDVN 83
           + R HS+   H       + +G LFP+      G  C             A+  A++ +N
Sbjct: 28  MQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQIN 87

Query: 84  SRRDILPDYEL-----------------------KLIHHDS---KCDPGQATKYLYELLY 117
              D+L +  L                        LI  D+   KC  G         ++
Sbjct: 88  KDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPP------IF 141

Query: 118 NDPIKI--ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATL 175
             P KI  ++    SSVS +VA   R++ +  +SY S++P LS+  R+  F R  P  + 
Sbjct: 142 TKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY 201

Query: 176 HNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKE-AGIEITFRQSFFSDP---- 230
                V +    GW  ++T+        S ++   +  +E  G+ I   Q    +P    
Sbjct: 202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGE 261

Query: 231 --AVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYD 288
              +  + L+  +AR ++    E + R++  E  K+      ++W  IG  +D+W     
Sbjct: 262 FEKIIKRLLETPNARAVIMFANEDDIRRIL-EAAKKLNQSGHFLW--IG--SDSWGSKIA 316

Query: 289 PSINCTVDEMTEAVEGHIT 307
           P     V +  E  EG +T
Sbjct: 317 P-----VYQQEEIAEGAVT 330


>gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]
          Length = 852

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 16/143 (11%)

Query: 74  AVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATK----------------YLYELLY 117
           A++MA+E++N++ D+LP   L     D+  +P  A K                Y     Y
Sbjct: 75  AMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQY 134

Query: 118 NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHN 177
              +  ++ P  S ++ +  +    + +  +SYG+S   LS R+ FP+FFRT PS  +  
Sbjct: 135 QPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQL 194

Query: 178 PTRVKLFEKWGWKKIATIQQTTE 200
               +L +++GW  +A +    E
Sbjct: 195 TAAAELLQEFGWNWVAALGSDDE 217


>gi|32528268 glutamate receptor, metabotropic 7 isoform b precursor
           [Homo sapiens]
          Length = 922

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 51/208 (24%), Positives = 86/208 (41%), Gaps = 35/208 (16%)

Query: 44  PHPSSERRAVYIGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDY 92
           PH       V +G LFP+    P G  C             A+  AL+ +NS  ++LP+ 
Sbjct: 40  PHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNV 99

Query: 93  ELKLIHHDSKCDPG-----QATKYLYELLYND----------------PIKIILMPGCS- 130
            L     D+ C        Q+  ++  L+  D                P K++ + G S 
Sbjct: 100 TLGARILDT-CSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASG 158

Query: 131 -SVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 189
            SVS +VA   R++ +  +SY S++P LS+ +R+  F R  P  +      V + +  GW
Sbjct: 159 SSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGW 218

Query: 190 KKIATIQQTTEVFTSTLDDLEERVKEAG 217
             ++T+          ++   +  KEAG
Sbjct: 219 NYVSTLASEGSYGEKGVESFTQISKEAG 246



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 57/276 (20%), Positives = 114/276 (41%), Gaps = 27/276 (9%)

Query: 481 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 540
           L+ LGI+  +  ++  I  +    ++ S   L+ +   G  L     F +      I + 
Sbjct: 597 LAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLM------IAKP 650

Query: 541 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 600
               VC  R   LGLG  + Y ++ TK   ++ +F + ++     + + P    A    L
Sbjct: 651 DVA-VCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSL 709

Query: 601 VGMDVLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGI 655
           + + +L + IW  VDP +  I+     T   E+ +  +   I      CS          
Sbjct: 710 ISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICS---------- 759

Query: 656 FYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDA 715
             GY  LL++     A +T+ V  E  N+ + +G  +Y   ++ L   P+    +   + 
Sbjct: 760 -LGYSILLMVTCTVYAIKTRGV-PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEK 817

Query: 716 AF---AFASLAIVFSSYITLVVLFVPKMRRLITRGE 748
            +      ++++  S+ + L +L++PK+  +I   E
Sbjct: 818 LYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPE 853


>gi|4504147 glutamate receptor, metabotropic 7 isoform a precursor
           [Homo sapiens]
          Length = 915

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 51/208 (24%), Positives = 86/208 (41%), Gaps = 35/208 (16%)

Query: 44  PHPSSERRAVYIGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDY 92
           PH       V +G LFP+    P G  C             A+  AL+ +NS  ++LP+ 
Sbjct: 40  PHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNV 99

Query: 93  ELKLIHHDSKCDPG-----QATKYLYELLYND----------------PIKIILMPGCS- 130
            L     D+ C        Q+  ++  L+  D                P K++ + G S 
Sbjct: 100 TLGARILDT-CSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASG 158

Query: 131 -SVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 189
            SVS +VA   R++ +  +SY S++P LS+ +R+  F R  P  +      V + +  GW
Sbjct: 159 SSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGW 218

Query: 190 KKIATIQQTTEVFTSTLDDLEERVKEAG 217
             ++T+          ++   +  KEAG
Sbjct: 219 NYVSTLASEGSYGEKGVESFTQISKEAG 246



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 57/276 (20%), Positives = 114/276 (41%), Gaps = 27/276 (9%)

Query: 481 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 540
           L+ LGI+  +  ++  I  +    ++ S   L+ +   G  L     F +      I + 
Sbjct: 597 LAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLM------IAKP 650

Query: 541 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 600
               VC  R   LGLG  + Y ++ TK   ++ +F + ++     + + P    A    L
Sbjct: 651 DVA-VCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSL 709

Query: 601 VGMDVLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGI 655
           + + +L + IW  VDP +  I+     T   E+ +  +   I      CS          
Sbjct: 710 ISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICS---------- 759

Query: 656 FYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDA 715
             GY  LL++     A +T+ V  E  N+ + +G  +Y   ++ L   P+    +   + 
Sbjct: 760 -LGYSILLMVTCTVYAIKTRGV-PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEK 817

Query: 716 AF---AFASLAIVFSSYITLVVLFVPKMRRLITRGE 748
            +      ++++  S+ + L +L++PK+  +I   E
Sbjct: 818 LYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPE 853


>gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens]
          Length = 841

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 56/222 (25%), Positives = 97/222 (43%), Gaps = 24/222 (10%)

Query: 74  AVEMALEDVNSRRDILPDYELKLIHHDSKCD-------------PGQATKYLY-ELLYND 119
           A+ + +E++N+   +LP+  L    +D   D             PGQ    L  +LL+  
Sbjct: 78  AMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYS 137

Query: 120 PIKIILMPGCSSVSTLVAEAARMWNLIV--LSYGSSSPALSNRQRFPTFFRTHPSATLHN 177
           P  ++ + G  S +     AA +   +V  +SY +SS  LS ++++P+F RT P+     
Sbjct: 138 PT-VLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQV 196

Query: 178 PTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVP---- 233
            T V L +K+GW  I+ +  + +     +  LE +    GI I F+        V     
Sbjct: 197 ETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERM 256

Query: 234 ---VKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYV 272
              +++L +  A ++V       AR  F  V    L GK +V
Sbjct: 257 QCLMRHLAQAGATVVVVFSSRQLARVFFESVVLTNLTGKVWV 298


>gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]
          Length = 480

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 56/222 (25%), Positives = 97/222 (43%), Gaps = 24/222 (10%)

Query: 74  AVEMALEDVNSRRDILPDYELKLIHHDSKCD-------------PGQATKYLY-ELLYND 119
           A+ + +E++N+   +LP+  L    +D   D             PGQ    L  +LL+  
Sbjct: 78  AMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYS 137

Query: 120 PIKIILMPGCSSVSTLVAEAARMWNLIV--LSYGSSSPALSNRQRFPTFFRTHPSATLHN 177
           P  ++ + G  S +     AA +   +V  +SY +SS  LS ++++P+F RT P+     
Sbjct: 138 PT-VLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQV 196

Query: 178 PTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVP---- 233
            T V L +K+GW  I+ +  + +     +  LE +    GI I F+        V     
Sbjct: 197 ETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERM 256

Query: 234 ---VKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYV 272
              +++L +  A ++V       AR  F  V    L GK +V
Sbjct: 257 QCLMRHLAQAGATVVVVFSSRQLARVFFESVVLTNLTGKVWV 298


>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
           [Homo sapiens]
          Length = 1212

 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 144/738 (19%), Positives = 280/738 (37%), Gaps = 136/738 (18%)

Query: 120 PIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPT 179
           PI  ++ PG SSV+  V    +++N+  ++Y ++S  LS++  F  F R  PS       
Sbjct: 142 PIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARA 201

Query: 180 RVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV--KNL 237
            V + +++ W  ++ +        S ++  ++   + GI I      +S+       K L
Sbjct: 202 MVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLL 261

Query: 238 KRQDARIIVGLFYETEARKV--FCE-------VYKERLFGKKYVWFLIGWYADNWFKIYD 288
           K+  + +        +AR V  FCE       +   R  G    + L+G  +D W   YD
Sbjct: 262 KKLTSHL-------PKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLG--SDGWADRYD 312

Query: 289 PSINCTVDEMTEAVEGHITTEI------------VMLNPANTRSISNMTSQEFVE-KLTK 335
                  D       G IT ++            + L P       N   QEF + +   
Sbjct: 313 -----VTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHR--NPWFQEFWQHRFQC 365

Query: 336 RLKRHPEETGGF---------------QEAPLAY--DAIWALALALN--KTSGGGGRSGV 376
           RL+  P+E   +               Q++ + +  +AI+++A  L+  + S   G +G+
Sbjct: 366 RLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGL 425

Query: 377 RLEDFNYNNQTITDQIYRAMNSSSFEGVSGH-VVFDASG-SRMAWTLIEQLQGGS----Y 430
                  + + + + + +    ++F GVSG  ++FD +G S   + ++   + G     Y
Sbjct: 426 CDAMKPIDGRKLLESLMK----TNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDY 481

Query: 431 KKIGYYDSTK----DDLSWSKTDKWIGG--SPPADQTLV----------------IKTFR 468
             +G +D+ +    DD  WSK    I    S P ++  +                 K   
Sbjct: 482 INVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENE 541

Query: 469 FLSQKLFISVSVLSS-------------------------LGIVLAVVCLSFNIYNSHVR 503
           ++  +       L S                           +V A + L   ++ + V 
Sbjct: 542 YVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVF 601

Query: 504 YIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGS 563
            I    P + + +   C + LA +    L  + +        C  +   +GL  ++ Y +
Sbjct: 602 IIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSA 661

Query: 564 MFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIET 623
           + TK   +  +    ++K   +K   P  + A   L++   ++ + +  IV         
Sbjct: 662 LVTKTNRIARILAGSKKKICTKK---PRFMSACAQLVIAFILICIQLGIIV-------AL 711

Query: 624 FAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKSVSTEK 681
           F  E P    D    P +         T LG+    GY GLL+L   F A++T++V    
Sbjct: 712 FIMEPPDIMHDY---PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA-N 767

Query: 682 INDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMR 741
            N+ + +   +Y   ++ L   P+    S+ +     F   ++  S+ + L  +FVPK+ 
Sbjct: 768 FNEAKYIAFTMYTTCIIWLAFVPI-YFGSNYKIITMCF---SVSLSATVALGCMFVPKVY 823

Query: 742 RLITRGEWQSEAQDTMKT 759
            ++ + E    +  T  T
Sbjct: 824 IILAKPERNVRSAFTTST 841


>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
           [Homo sapiens]
          Length = 1180

 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 144/738 (19%), Positives = 280/738 (37%), Gaps = 136/738 (18%)

Query: 120 PIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPT 179
           PI  ++ PG SSV+  V    +++N+  ++Y ++S  LS++  F  F R  PS       
Sbjct: 142 PIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARA 201

Query: 180 RVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV--KNL 237
            V + +++ W  ++ +        S ++  ++   + GI I      +S+       K L
Sbjct: 202 MVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLL 261

Query: 238 KRQDARIIVGLFYETEARKV--FCE-------VYKERLFGKKYVWFLIGWYADNWFKIYD 288
           K+  + +        +AR V  FCE       +   R  G    + L+G  +D W   YD
Sbjct: 262 KKLTSHL-------PKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLG--SDGWADRYD 312

Query: 289 PSINCTVDEMTEAVEGHITTEI------------VMLNPANTRSISNMTSQEFVE-KLTK 335
                  D       G IT ++            + L P       N   QEF + +   
Sbjct: 313 -----VTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHR--NPWFQEFWQHRFQC 365

Query: 336 RLKRHPEETGGF---------------QEAPLAY--DAIWALALALN--KTSGGGGRSGV 376
           RL+  P+E   +               Q++ + +  +AI+++A  L+  + S   G +G+
Sbjct: 366 RLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGL 425

Query: 377 RLEDFNYNNQTITDQIYRAMNSSSFEGVSGH-VVFDASG-SRMAWTLIEQLQGGS----Y 430
                  + + + + + +    ++F GVSG  ++FD +G S   + ++   + G     Y
Sbjct: 426 CDAMKPIDGRKLLESLMK----TNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDY 481

Query: 431 KKIGYYDSTK----DDLSWSKTDKWIGG--SPPADQTLV----------------IKTFR 468
             +G +D+ +    DD  WSK    I    S P ++  +                 K   
Sbjct: 482 INVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENE 541

Query: 469 FLSQKLFISVSVLSS-------------------------LGIVLAVVCLSFNIYNSHVR 503
           ++  +       L S                           +V A + L   ++ + V 
Sbjct: 542 YVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVF 601

Query: 504 YIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGS 563
            I    P + + +   C + LA +    L  + +        C  +   +GL  ++ Y +
Sbjct: 602 IIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSA 661

Query: 564 MFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIET 623
           + TK   +  +    ++K   +K   P  + A   L++   ++ + +  IV         
Sbjct: 662 LVTKTNRIARILAGSKKKICTKK---PRFMSACAQLVIAFILICIQLGIIV-------AL 711

Query: 624 FAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKSVSTEK 681
           F  E P    D    P +         T LG+    GY GLL+L   F A++T++V    
Sbjct: 712 FIMEPPDIMHDY---PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA-N 767

Query: 682 INDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMR 741
            N+ + +   +Y   ++ L   P+    S+ +     F   ++  S+ + L  +FVPK+ 
Sbjct: 768 FNEAKYIAFTMYTTCIIWLAFVPI-YFGSNYKIITMCF---SVSLSATVALGCMFVPKVY 823

Query: 742 RLITRGEWQSEAQDTMKT 759
            ++ + E    +  T  T
Sbjct: 824 IILAKPERNVRSAFTTST 841


>gi|167830411 natriuretic peptide receptor 1 [Homo sapiens]
          Length = 1061

 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 89/416 (21%), Positives = 155/416 (37%), Gaps = 50/416 (12%)

Query: 73  PAVEMALEDVNSRRDILPDYELKLIHHDSK-----CDPGQATKYLYELLYNDPIKIILMP 127
           PAVE+AL  V +R D+LP + ++ +   S+     C    A     +L +     + L P
Sbjct: 57  PAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGP 116

Query: 128 GCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKW 187
           GC   +  V      W + +L+ G+ +     +  +    R  PS          L  + 
Sbjct: 117 GCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRL 176

Query: 188 GWKKIATIQQT-----TEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKR--- 239
           GW++ A +         E     ++ L  RV++          F  D       L R   
Sbjct: 177 GWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMP 236

Query: 240 QDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMT 299
           +  R+I         R +     +  L G+ YV+F +  +  +      P+         
Sbjct: 237 RKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPR----RPW 292

Query: 300 EAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLK-------RHPEETGGFQEAPL 352
           E  +G   +       A   +  +  + E++E L K+LK           E G     P 
Sbjct: 293 ERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFL-KQLKHLAYEQFNFTMEDGLVNTIPA 351

Query: 353 AY-DAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITD--QIYRAMNSSSFEGVSGHVV 409
           ++ D +     A+ +T   GG              T+TD   I + M + SF+GV+G++ 
Sbjct: 352 SFHDGLLLYIQAVTETLAHGG--------------TVTDGENITQRMWNRSFQGVTGYLK 397

Query: 410 FDASGSR----MAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDK--WIGGSPPAD 459
            D+SG R      W +    + G+++ +  Y+ T  +L      K  W  G PP D
Sbjct: 398 IDSSGDRETDFSLWDM--DPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPD 451


>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
           sapiens]
          Length = 877

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 56/287 (19%), Positives = 116/287 (40%), Gaps = 17/287 (5%)

Query: 480 VLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGR 539
           +L+ LGIV     ++  +  ++   ++ S   L+ +   G  L  A  F +  +      
Sbjct: 591 LLAVLGIVATTTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAE------ 644

Query: 540 NQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGL 599
                VC AR   LGLG +L Y ++ TK   ++ +F + +        + P         
Sbjct: 645 -PGAAVCAARRLFLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFS 703

Query: 600 LVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGY 659
           L  + V+ +  W    P H  I+     E +  +D      +  C    ++  +G   GY
Sbjct: 704 LTSLQVVGMIAWLGARPPHSVID----YEEQRTVDPEQARGVLKCDMSDLSL-IGCL-GY 757

Query: 660 KGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAF-- 717
             LL++     A + + V  E  N+ + +G  +Y   ++ L   P+    +   +  +  
Sbjct: 758 SLLLMVTCTVYAIKARGV-PETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQ 816

Query: 718 -AFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST 763
               ++++  S+ ++L +L+VPK   ++   E   + +      +ST
Sbjct: 817 TTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKATST 863



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 47/201 (23%), Positives = 83/201 (41%), Gaps = 38/201 (18%)

Query: 55  IGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDYEL--KLIHHDS 101
           +G LFP+      G+AC             A+  AL+ VN+  ++LP   L  +L+   S
Sbjct: 41  LGGLFPVHARGAAGRACGQLKKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCS 100

Query: 102 KCDPG--QATKYLYELLYN---------------------DPIKIILMPGCS--SVSTLV 136
           +      QA  ++  L+                        P +++ + G S  SVS +V
Sbjct: 101 RDTYALEQALSFVQALIRGRGDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMV 160

Query: 137 AEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQ 196
           A   R++ +  +SY S++P LS+  R+  F R  P  +      V +    GW  ++T+ 
Sbjct: 161 ANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLA 220

Query: 197 QTTEVFTSTLDDLEERVKEAG 217
                  S ++   +  +EAG
Sbjct: 221 SEGNYGESGVEAFVQISREAG 241


>gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo
           sapiens]
          Length = 254

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 47/200 (23%), Positives = 82/200 (41%), Gaps = 12/200 (6%)

Query: 545 VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD 604
           VC  R   LG  FS+ Y ++ TK   +  +F    E  +  + + P    A    L+   
Sbjct: 13  VCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQ 72

Query: 605 VLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLL 664
           +L +  W +V+          KE   E  +V  L     C+ R   + LG    Y  LL+
Sbjct: 73  LLIVVAWLVVE-----APGTGKETAPERREVVTL----RCNHRDA-SMLGSL-AYNVLLI 121

Query: 665 LLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAI 724
            L    A++T+    E  N+ + +G  +Y   ++ L   P+  + SS          +++
Sbjct: 122 ALCTLYAFKTRK-CPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSV 180

Query: 725 VFSSYITLVVLFVPKMRRLI 744
             S  + L  LF PK+  ++
Sbjct: 181 SLSGSVVLGCLFAPKLHIIL 200


>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
           [Homo sapiens]
          Length = 872

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 47/200 (23%), Positives = 82/200 (41%), Gaps = 12/200 (6%)

Query: 545 VCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMD 604
           VC  R   LG  FS+ Y ++ TK   +  +F    E  +  + + P    A    L+   
Sbjct: 631 VCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQ 690

Query: 605 VLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLLL 664
           +L +  W +V+          KE   E  +V  L     C+ R   + LG    Y  LL+
Sbjct: 691 LLIVVAWLVVE-----APGTGKETAPERREVVTL----RCNHRDA-SMLGSL-AYNVLLI 739

Query: 665 LLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAI 724
            L    A++T+    E  N+ + +G  +Y   ++ L   P+  + SS          +++
Sbjct: 740 ALCTLYAFKTRK-CPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSV 798

Query: 725 VFSSYITLVVLFVPKMRRLI 744
             S  + L  LF PK+  ++
Sbjct: 799 SLSGSVVLGCLFAPKLHIIL 818



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 42/187 (22%), Positives = 78/187 (41%), Gaps = 18/187 (9%)

Query: 130 SSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 189
           S VS  VA   R++ +  +SY S+S  LS++ R+  F RT P          ++   + W
Sbjct: 145 SDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNW 204

Query: 190 KKIATIQQTTEVFTSTLD--DLEERVKEAGI----EITFRQSFFSDPAVPVKNLKRQDAR 243
             ++T+    +   + ++  +LE R +   +    ++    S  +   V    L++  AR
Sbjct: 205 TYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSAR 264

Query: 244 IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE 303
           + V      +AR++      +RL    + W      +D W      ++   V     A E
Sbjct: 265 VAVLFTRSEDARELLAA--SQRL-NASFTWVA----SDGW-----GALESVVAGSEGAAE 312

Query: 304 GHITTEI 310
           G IT E+
Sbjct: 313 GAITIEL 319


>gi|37577159 calcium-sensing receptor [Homo sapiens]
          Length = 1078

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 7/149 (4%)

Query: 130 SSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 189
           S VST VA    ++ +  +SY SSS  LSN+ +F +F RT P+          + E + W
Sbjct: 147 SGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRW 206

Query: 190 KKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQ--SFFSDPAV---PVKNLKRQDARI 244
             + TI    +     ++   E  +E  I I F +  S +SD       V+ ++   A++
Sbjct: 207 NWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSDEEEIQHVVEVIQNSTAKV 266

Query: 245 IVGLFYETEARKVFCEVYKERLFGKKYVW 273
           IV      +   +  E+ +  + GK  +W
Sbjct: 267 IVVFSSGPDLEPLIKEIVRRNITGK--IW 293


>gi|4505441 natriuretic peptide receptor C/guanylate cyclase C
           (atrionatriuretic peptide receptor C) [Homo sapiens]
          Length = 540

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 82/387 (21%), Positives = 154/387 (39%), Gaps = 46/387 (11%)

Query: 72  QPAVEMALEDVNS----RRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIK--IIL 125
           +PA+E AL  V      RR + P    ++ + DS C        +  +      K  +IL
Sbjct: 73  RPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLIL 132

Query: 126 MPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNR-QRFPTFFRTHPSATLHNPTRVKLF 184
            P C   +  VA  A  W+L +LS G+ +    ++   +    R  P+        + LF
Sbjct: 133 GPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALF 192

Query: 185 EKWGWKKIATIQQTTEVFTS---TLDDLEERVKEAGIE---ITFRQSFFSDPAVPVKNLK 238
               W + A +    ++  +   TL+ + E  +E G+     +F ++   D    V+N++
Sbjct: 193 RHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ 252

Query: 239 RQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEM 298
             + R+++        R +    ++  +    Y +F I  +  N     D S        
Sbjct: 253 ASE-RVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELF--NSSSYGDGSWKRGDKHD 309

Query: 299 TEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPL------ 352
            EA + + + + V        ++      EF EK +  +K   E+ G   E  +      
Sbjct: 310 FEAKQAYSSLQTV--------TLLRTVKPEF-EKFSMEVKSSVEKQGLNMEDYVNMFVEG 360

Query: 353 AYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDA 412
            +DAI    LAL++      R+G   +D          +I +   + +FEG++G V  DA
Sbjct: 361 FHDAILLYVLALHEVL----RAGYSKKD--------GGKIIQQTWNRTFEGIAGQVSIDA 408

Query: 413 SGSR---MAWTLIEQLQGGSYKKIGYY 436
           +G R    +   +  ++ G+ + IG Y
Sbjct: 409 NGDRYGDFSVIAMTDVEAGTQEVIGDY 435


>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
           precursor [Homo sapiens]
          Length = 906

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 35/165 (21%), Positives = 72/165 (43%), Gaps = 10/165 (6%)

Query: 65  WPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKII 124
           W    A + ++E   + + S RD   D   + +       PG+  K         PI  +
Sbjct: 110 WHSSVALEQSIEFIRDSLISIRDE-KDGINRCLPDGQSLPPGRTKK---------PIAGV 159

Query: 125 LMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLF 184
           + PG SSV+  V    +++++  ++Y ++S  LS++  +  F R  PS TL     + + 
Sbjct: 160 IGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIV 219

Query: 185 EKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSD 229
           +++ W  ++ +        S +D  +E   + G+ I      +S+
Sbjct: 220 KRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSN 264



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 56/312 (17%), Positives = 122/312 (39%), Gaps = 39/312 (12%)

Query: 442 DLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAV-VCLSFNIYNS 500
           DL W     W        + + ++   + + +  I+++  S LGI++ + V L F +Y  
Sbjct: 566 DLGW-----WPNADLTGCEPIPVRYLEWSNIESIIAIA-FSCLGILVTLFVTLIFVLYRD 619

Query: 501 HVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLG 560
                    P + + +   C + LA +F   +  + +        C  +  L+GL  ++ 
Sbjct: 620 --------TPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMC 671

Query: 561 YGSMFTKIWWVHTVFTKKEEKKEWRKT--LEPWKLYATVGLLVGMDVLTLAIWQIVDPLH 618
           Y ++ TK   +  +    ++K   RK   +  W       +L+ + +  +    I++P  
Sbjct: 672 YSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEP-- 729

Query: 619 RTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKS 676
                         + +   P ++        + LG+    GY GLL++   + A++T++
Sbjct: 730 -------------PMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRN 776

Query: 677 VSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLF 736
           V     N+ + +   +Y   ++ L   P+        +        A+  S  + L  +F
Sbjct: 777 VPA-NFNEAKYIAFTMYTTCIIWLAFVPIYF----GSNYKIITTCFAVSLSVTVALGCMF 831

Query: 737 VPKMRRLITRGE 748
            PKM  +I + E
Sbjct: 832 TPKMYIIIAKPE 843


>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
           precursor [Homo sapiens]
          Length = 1194

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 35/165 (21%), Positives = 72/165 (43%), Gaps = 10/165 (6%)

Query: 65  WPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKII 124
           W    A + ++E   + + S RD   D   + +       PG+  K         PI  +
Sbjct: 110 WHSSVALEQSIEFIRDSLISIRDE-KDGINRCLPDGQSLPPGRTKK---------PIAGV 159

Query: 125 LMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLF 184
           + PG SSV+  V    +++++  ++Y ++S  LS++  +  F R  PS TL     + + 
Sbjct: 160 IGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIV 219

Query: 185 EKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSD 229
           +++ W  ++ +        S +D  +E   + G+ I      +S+
Sbjct: 220 KRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSN 264



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 56/312 (17%), Positives = 122/312 (39%), Gaps = 39/312 (12%)

Query: 442 DLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAV-VCLSFNIYNS 500
           DL W     W        + + ++   + + +  I+++  S LGI++ + V L F +Y  
Sbjct: 566 DLGW-----WPNADLTGCEPIPVRYLEWSNIESIIAIA-FSCLGILVTLFVTLIFVLYRD 619

Query: 501 HVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLG 560
                    P + + +   C + LA +F   +  + +        C  +  L+GL  ++ 
Sbjct: 620 --------TPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMC 671

Query: 561 YGSMFTKIWWVHTVFTKKEEKKEWRKT--LEPWKLYATVGLLVGMDVLTLAIWQIVDPLH 618
           Y ++ TK   +  +    ++K   RK   +  W       +L+ + +  +    I++P  
Sbjct: 672 YSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEP-- 729

Query: 619 RTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKS 676
                         + +   P ++        + LG+    GY GLL++   + A++T++
Sbjct: 730 -------------PMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRN 776

Query: 677 VSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLF 736
           V     N+ + +   +Y   ++ L   P+        +        A+  S  + L  +F
Sbjct: 777 VPA-NFNEAKYIAFTMYTTCIIWLAFVPIYF----GSNYKIITTCFAVSLSVTVALGCMF 831

Query: 737 VPKMRRLITRGE 748
            PKM  +I + E
Sbjct: 832 TPKMYIIIAKPE 843


>gi|93352554 GPR158-like 1 [Homo sapiens]
          Length = 2367

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 52/202 (25%), Positives = 88/202 (43%), Gaps = 12/202 (5%)

Query: 544 FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM 603
           F C A  W+  LGF++ YG++  K++ V  +F  +  ++     L   +L   +GLL+  
Sbjct: 443 FRCIALRWVRLLGFAIVYGTIILKLYRVLQLFLSRTAQRS--ALLSSGRLLRRLGLLLLP 500

Query: 604 DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL 663
            +  LA+W  V  L R I+          +     P   H      + W  I    + LL
Sbjct: 501 VLGFLAVW-TVGALERGIQHAPL------VIRGHTPSGRHFYLCHHDRWDYIMVVAELLL 553

Query: 664 LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVL--CLITAPVTMILSSQQDAAFAFAS 721
           L  G FL Y T++V     ++ R +G+A++N  +L     TA   ++ S   D       
Sbjct: 554 LCWGSFLCYATRAV-LSAFHEPRYMGIALHNELLLSAAFHTARFVLVPSLHPDWTLLLFF 612

Query: 722 LAIVFSSYITLVVLFVPKMRRL 743
                +   TL ++F+PK  +L
Sbjct: 613 FHTHSTVTTTLALIFIPKFWKL 634


>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
          Length = 839

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 51/205 (24%), Positives = 81/205 (39%), Gaps = 15/205 (7%)

Query: 68  GQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYND---PIK-- 122
           G     A+  A+E++N+   +LP   L     D           LY L + D   PI+  
Sbjct: 68  GYNLMQAMRFAVEEINNDSSLLPGVLLGYEIVDVCYISNNVQPVLYFLAHEDNLLPIQED 127

Query: 123 ---------IILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSA 173
                     ++ P  S     VA    ++ L  ++Y + S  L ++ RFP   RT PSA
Sbjct: 128 YSNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSA 187

Query: 174 TLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFS-DPAV 232
             H    V+L   + W  I  +  +          L ERV    I I F+++  +  P  
Sbjct: 188 DHHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERVARRDICIAFQETLPTLQPNQ 247

Query: 233 PVKNLKRQDARIIVGLFYETEARKV 257
            + + +RQ    IV    ++ AR V
Sbjct: 248 NMTSEERQRLVTIVDKLQQSTARVV 272


>gi|112807234 G protein-coupled receptor, family C, group 6, member
           A [Homo sapiens]
          Length = 926

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 3/122 (2%)

Query: 117 YNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLH 176
           Y   +K ++  G S ++  V+    +  +  + Y S++  LS++ RFP+F RT PS    
Sbjct: 136 YMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKIRFPSFLRTVPSDFHQ 195

Query: 177 NPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQ---SFFSDPAVP 233
                 L +K GW  I  I    +     L+    + +   + I F++   +F SD  + 
Sbjct: 196 IKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIAFKEVLPAFLSDNTIE 255

Query: 234 VK 235
           V+
Sbjct: 256 VR 257



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 63/282 (22%), Positives = 113/282 (40%), Gaps = 33/282 (11%)

Query: 471 SQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPL 530
           +  L I + +LS LGI+  +V       N +   +++S         V   + L      
Sbjct: 590 NDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVKSSGG-----LRVCYVILLCHFLNF 644

Query: 531 GLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEP 590
               + IG  Q  F C+ R  + G+ F+L    + TK   +   F+   + +++ K L  
Sbjct: 645 ASTSFFIGEPQ-DFTCKTRQTMFGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCL-- 701

Query: 591 WKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQ--LEHCSSRK 648
           ++    +    G+ V+   +W I          FA   P  +++VS LP+  +  C    
Sbjct: 702 YRPILIIFTCTGIQVVICTLWLI----------FA--APTVEVNVS-LPRVIILECEEGS 748

Query: 649 MNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAV--GMAIYNVAVLCLITAPVT 706
           +  + G   GY  +L  +    A++ K    E  N+ + +  GM IY +A +  I    T
Sbjct: 749 ILAF-GTMLGYIAILAFICFIFAFKGK---YENYNEAKFITFGMLIYFIAWITFIPIYAT 804

Query: 707 MILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGE 748
                      A   + I+ S+Y  L   F+PK   +I + E
Sbjct: 805 TF----GKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQE 842


>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
           sapiens]
          Length = 879

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 36/156 (23%), Positives = 72/156 (46%), Gaps = 14/156 (8%)

Query: 113 YELLYNDPIKI--ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTH 170
           Y +  N P+ I  ++    SSVS  VA   R++ +  +SY S+S  LS++ R+  F RT 
Sbjct: 132 YAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTV 191

Query: 171 PSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEI---------T 221
           P          ++   + W  ++T+    +   + ++  E+  +   I I          
Sbjct: 192 PPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSN 251

Query: 222 FRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKV 257
            R+S+ S   V  + L++ +AR++V      ++R++
Sbjct: 252 IRKSYDS---VIRELLQKPNARVVVLFMRSDDSREL 284


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 765 NNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQL--RSRRHPPTPPEPSGGLP 822
           +N +++  LLE++ +ELE      EE+   L+H +   Q+   +S    P PP P   LP
Sbjct: 304 HNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLP 363

Query: 823 RGPPEP 828
             PP P
Sbjct: 364 PPPPNP 369


>gi|50511340 shootin1 isoform b [Homo sapiens]
          Length = 456

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 765 NNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQL--RSRRHPPTPPEPSGGLP 822
           +N +++  LLE++ +ELE      EE+   L+H +   Q+   +S    P PP P   LP
Sbjct: 304 HNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLP 363

Query: 823 RGPPEP 828
             PP P
Sbjct: 364 PPPPNP 369


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,465,578
Number of Sequences: 37866
Number of extensions: 1675090
Number of successful extensions: 12794
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 11511
Number of HSP's gapped (non-prelim): 1336
length of query: 844
length of database: 18,247,518
effective HSP length: 111
effective length of query: 733
effective length of database: 14,044,392
effective search space: 10294539336
effective search space used: 10294539336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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