Guide to the Human Genome
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Search of human proteins with 219802797

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|219802797 transmembrane protein 106C isoform b [Homo
sapiens]
         (231 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219802857 transmembrane protein 106C isoform b [Homo sapiens]      459   e-130
gi|219802797 transmembrane protein 106C isoform b [Homo sapiens]      459   e-130
gi|219802834 transmembrane protein 106C isoform a [Homo sapiens]      448   e-126
gi|13129026 transmembrane protein 106C isoform a [Homo sapiens]       448   e-126
gi|197116389 transmembrane protein 106B [Homo sapiens]                200   7e-52
gi|40254893 transmembrane protein 106B [Homo sapiens]                 200   7e-52
gi|21450796 transmembrane protein 106A [Homo sapiens]                 132   2e-31
gi|196123580 NADH dehydrogenase subunit 2 [Homo sapiens neandert...    33   0.16 
gi|251831108 NADH dehydrogenase subunit 2 [Homo sapiens]               32   0.60 
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ...    30   1.3  
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i...    30   1.3  
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i...    30   1.3  
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i...    30   1.3  
gi|4506591 retinal pigment epithelium-specific protein 65kDa [Ho...    30   1.7  
gi|160948599 integrator complex subunit 1 [Homo sapiens]               30   2.3  
gi|145587088 hypothetical protein LOC165186 [Homo sapiens]             29   3.9  
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]            28   6.6  
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]            28   6.6  

>gi|219802857 transmembrane protein 106C isoform b [Homo sapiens]
          Length = 231

 Score =  459 bits (1182), Expect = e-130
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60
           MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
Sbjct: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60

Query: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120
           PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
Sbjct: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120

Query: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMGGPFSY 180
           VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMGGPFSY
Sbjct: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMGGPFSY 180

Query: 181 VYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNSTAI 231
           VYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNSTAI
Sbjct: 181 VYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNSTAI 231


>gi|219802797 transmembrane protein 106C isoform b [Homo sapiens]
          Length = 231

 Score =  459 bits (1182), Expect = e-130
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60
           MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
Sbjct: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60

Query: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120
           PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
Sbjct: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120

Query: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMGGPFSY 180
           VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMGGPFSY
Sbjct: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMGGPFSY 180

Query: 181 VYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNSTAI 231
           VYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNSTAI
Sbjct: 181 VYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNSTAI 231


>gi|219802834 transmembrane protein 106C isoform a [Homo sapiens]
          Length = 250

 Score =  448 bits (1152), Expect = e-126
 Identities = 231/250 (92%), Positives = 231/250 (92%), Gaps = 19/250 (7%)

Query: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60
           MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
Sbjct: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60

Query: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120
           PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
Sbjct: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120

Query: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTV--------------- 165
           VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTV               
Sbjct: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR 180

Query: 166 ----VNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 221
               VNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY
Sbjct: 181 SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 240

Query: 222 VDCGGNSTAI 231
           VDCGGNSTAI
Sbjct: 241 VDCGGNSTAI 250


>gi|13129026 transmembrane protein 106C isoform a [Homo sapiens]
          Length = 250

 Score =  448 bits (1152), Expect = e-126
 Identities = 231/250 (92%), Positives = 231/250 (92%), Gaps = 19/250 (7%)

Query: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60
           MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI
Sbjct: 1   MGSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAIAQFPYVEFTGRDSITCLTCQGTGYI 60

Query: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120
           PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV
Sbjct: 61  PTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKV 120

Query: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTV--------------- 165
           VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTV               
Sbjct: 121 VKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVSTYVTTNVSLIPPR 180

Query: 166 ----VNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 221
               VNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY
Sbjct: 181 SEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHY 240

Query: 222 VDCGGNSTAI 231
           VDCGGNSTAI
Sbjct: 241 VDCGGNSTAI 250


>gi|197116389 transmembrane protein 106B [Homo sapiens]
          Length = 274

 Score =  200 bits (509), Expect = 7e-52
 Identities = 111/238 (46%), Positives = 148/238 (62%), Gaps = 30/238 (12%)

Query: 19  EDDRDGLLAEREQEEA-----IAQFPYVEFTGRDSITCLTCQGTGYIPTEQVNELVALIP 73
           E+ R+GL+      E      ++QFPYVEFTGRDS+TC TCQGTG IP  Q N+LVALIP
Sbjct: 24  ENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIP 83

Query: 74  HSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKVVKVTFNKQDSLVI 133
           +SDQRLRP+RTK YV+ S+ +CLL SGL VFFLFP S+ V   G+K   V+++ Q   + 
Sbjct: 84  YSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIY 143

Query: 134 LTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMG-----GP----------- 177
           L I  TL I N+N+Y+V V ++++Q+Q+  TV+   GKA +      GP           
Sbjct: 144 LNITNTLNITNNNYYSVEVENITAQVQFSKTVI---GKARLNNITIIGPLDMKQIDYTVP 200

Query: 178 ------FSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNST 229
                  SY+Y FCT+  I VHNIV+ M+ +V  +Y G   Q S E + YVDCG N+T
Sbjct: 201 TVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTT 258


>gi|40254893 transmembrane protein 106B [Homo sapiens]
          Length = 274

 Score =  200 bits (509), Expect = 7e-52
 Identities = 111/238 (46%), Positives = 148/238 (62%), Gaps = 30/238 (12%)

Query: 19  EDDRDGLLAEREQEEA-----IAQFPYVEFTGRDSITCLTCQGTGYIPTEQVNELVALIP 73
           E+ R+GL+      E      ++QFPYVEFTGRDS+TC TCQGTG IP  Q N+LVALIP
Sbjct: 24  ENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIP 83

Query: 74  HSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKVVKVTFNKQDSLVI 133
           +SDQRLRP+RTK YV+ S+ +CLL SGL VFFLFP S+ V   G+K   V+++ Q   + 
Sbjct: 84  YSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRSIDVKYIGVKSAYVSYDVQKRTIY 143

Query: 134 LTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMG-----GP----------- 177
           L I  TL I N+N+Y+V V ++++Q+Q+  TV+   GKA +      GP           
Sbjct: 144 LNITNTLNITNNNYYSVEVENITAQVQFSKTVI---GKARLNNITIIGPLDMKQIDYTVP 200

Query: 178 ------FSYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDCGGNST 229
                  SY+Y FCT+  I VHNIV+ M+ +V  +Y G   Q S E + YVDCG N+T
Sbjct: 201 TVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHSEQISQERYQYVDCGRNTT 258


>gi|21450796 transmembrane protein 106A [Homo sapiens]
          Length = 262

 Score =  132 bits (332), Expect = 2e-31
 Identities = 72/198 (36%), Positives = 113/198 (57%), Gaps = 19/198 (9%)

Query: 49  ITCLTCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFP 108
           +TC TCQG+G IP E   +LVALIP+ DQRL+P+ TK +V L++L+CL+ S  +VFFLFP
Sbjct: 57  VTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFP 116

Query: 109 HSVLVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNF 168
            SV+V   G+    V F++ D  + L I   L I N N+Y + VT L+ ++ +++ VV  
Sbjct: 117 RSVIVQPAGLNSSTVAFDEAD--IYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQ 174

Query: 169 TGKAEM--GGPFS---------------YVYFFCTVPEILVHNIVIFMRTSVKISYIGLM 211
                +   GP +                 Y  CT  EI VH++++ ++ ++  SY+   
Sbjct: 175 VSNNLLLHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHS 234

Query: 212 TQSSLETHHYVDCGGNST 229
            Q   +++ YVDC GN++
Sbjct: 235 EQLVFQSYEYVDCRGNAS 252


>gi|196123580 NADH dehydrogenase subunit 2 [Homo sapiens
           neanderthalensis]
          Length = 347

 Score = 33.5 bits (75), Expect = 0.16
 Identities = 21/68 (30%), Positives = 34/68 (50%)

Query: 125 FNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMGGPFSYVYFF 184
           F K +SL+I TIMAT+ + N  FY   + S S  +  M+  V    + E   P  ++   
Sbjct: 270 FTKNNSLIIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNVKMKWQFEHTKPTPFLPTL 329

Query: 185 CTVPEILV 192
            T+  +L+
Sbjct: 330 ITLTTLLL 337


>gi|251831108 NADH dehydrogenase subunit 2 [Homo sapiens]
          Length = 347

 Score = 31.6 bits (70), Expect = 0.60
 Identities = 19/57 (33%), Positives = 29/57 (50%)

Query: 125 FNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGKAEMGGPFSYV 181
           F K +SL+I TIMAT+ + N  FY   + S S  +  M+  V    + E   P  ++
Sbjct: 270 FTKNNSLIIPTIMATITLLNLYFYLRLIYSTSITLLPMSNNVKMKWQFEHTKPTPFL 326


>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
          isoform d [Homo sapiens]
          Length = 458

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2  GSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAI 35
          GS  S  +RPS      E+DR+ +  EREQ+ AI
Sbjct: 50 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAI 83


>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
          isoform a [Homo sapiens]
          Length = 486

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2  GSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAI 35
          GS  S  +RPS      E+DR+ +  EREQ+ AI
Sbjct: 16 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAI 49


>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
          isoform c [Homo sapiens]
          Length = 502

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2  GSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAI 35
          GS  S  +RPS      E+DR+ +  EREQ+ AI
Sbjct: 32 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAI 65


>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
          isoform b [Homo sapiens]
          Length = 520

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 15/34 (44%), Positives = 20/34 (58%)

Query: 2  GSQHSAAARPSSCRRKQEDDRDGLLAEREQEEAI 35
          GS  S  +RPS      E+DR+ +  EREQ+ AI
Sbjct: 50 GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAI 83


>gi|4506591 retinal pigment epithelium-specific protein 65kDa [Homo
           sapiens]
          Length = 533

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 5/46 (10%)

Query: 179 SYVYFFCTVPEILVHNIVIFMRTSVKISYIGLMTQSSLETHHYVDC 224
           SYV+ F   P     N ++F+ T VKI+    ++  SL   +Y+DC
Sbjct: 238 SYVHSFGLTP-----NYIVFVETPVKINLFKFLSSWSLWGANYMDC 278


>gi|160948599 integrator complex subunit 1 [Homo sapiens]
          Length = 2190

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 17/54 (31%), Positives = 27/54 (50%)

Query: 118 IKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNFTGK 171
           +K +KVT  K DS + L++M   KI+ + F T  V      +   +  +NF  K
Sbjct: 146 VKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAK 199


>gi|145587088 hypothetical protein LOC165186 [Homo sapiens]
          Length = 1019

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 15/127 (11%)

Query: 53  TCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVL 112
           T QG G +  EQ+ EL  L+   D R R +   Q + L      L +  +V      +  
Sbjct: 756 TLQGRGEM-VEQLRELTRLLEAKDFRSRMEGVGQLLELCKAKTELVTAHLVQVFDAFTPR 814

Query: 113 VDDDGIKV--------VKVTFNKQDSL------VILTIMATLKIRNSNFYTVAVTSLSSQ 158
           + D   KV         K+    ++SL      +I+T+   L  +NS  Y  AV  L + 
Sbjct: 815 LQDSNKKVNQWALESFAKMIPLLRESLHPMLLSIIITVADNLNSKNSGIYAAAVAVLDAM 874

Query: 159 IQYMNTV 165
           ++ ++ +
Sbjct: 875 VESLDNL 881


>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
          Length = 785

 Score = 28.1 bits (61), Expect = 6.6
 Identities = 12/41 (29%), Positives = 22/41 (53%)

Query: 112 LVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAV 152
           +VD DG+ + K++ +K+    I+TI   L       YT+ +
Sbjct: 301 IVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRI 341


>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
          Length = 785

 Score = 28.1 bits (61), Expect = 6.6
 Identities = 12/41 (29%), Positives = 22/41 (53%)

Query: 112 LVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAV 152
           +VD DG+ + K++ +K+    I+TI   L       YT+ +
Sbjct: 301 IVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRI 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,069,124
Number of Sequences: 37866
Number of extensions: 312395
Number of successful extensions: 809
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 787
Number of HSP's gapped (non-prelim): 18
length of query: 231
length of database: 18,247,518
effective HSP length: 99
effective length of query: 132
effective length of database: 14,498,784
effective search space: 1913839488
effective search space used: 1913839488
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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