Search of human proteins with 219521926

Search of human proteins with 219521926

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|219521926 DC-STAMP domain containing 1 isoform 2 [Homo
sapiens]
         (681 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219521926 DC-STAMP domain containing 1 isoform 2 [Homo sapiens]   1395   0.0  
gi|219521924 DC-STAMP domain containing 1 isoform 1 [Homo sapiens]   1381   0.0  
gi|109240536 DC-STAMP domain containing 2 [Homo sapiens]              167   3e-41
gi|13540565 dendritic cell-specific transmembrane protein [Homo ...    70   6e-12
gi|239757512 PREDICTED: chromosome 20 open reading frame 123 [Ho...    37   0.060
gi|239752028 PREDICTED: hypothetical protein LOC128506 [Homo sap...    37   0.060
gi|239746512 PREDICTED: hypothetical protein LOC128506 [Homo sap...    37   0.060
gi|225637556 hypothetical protein LOC128506 [Homo sapiens]             37   0.060
gi|239757412 PREDICTED: hypothetical protein XP_002345272 [Homo ...    33   1.1  
gi|134031945 SCO-spondin [Homo sapiens]                                32   1.5  
gi|7657522 ring finger protein 7 isoform 1 [Homo sapiens]              32   2.5  
gi|109134327 PTD016 protein [Homo sapiens]                             31   3.3  
gi|219555718 synaptonemal complex central element protein 1 isof...    31   4.3  
gi|219555716 synaptonemal complex central element protein 1 isof...    31   4.3  
gi|18640754 synaptonemal complex central element protein 1 isofo...    31   4.3  
gi|158186614 transmembrane protein 118 isoform 1 [Homo sapiens]        31   4.3  
gi|239746366 PREDICTED: hypothetical protein XP_002343738 [Homo ...    30   5.6  
gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo s...    30   5.6  
gi|4504713 insulinoma-associated 1 [Homo sapiens]                      30   5.6  
gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapi...    30   7.4  
gi|21361493 ring finger protein 141 [Homo sapiens]                     30   7.4  
gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1 ...    30   9.6  
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    30   9.6  
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    30   9.6  

>gi|219521926 DC-STAMP domain containing 1 isoform 2 [Homo sapiens]
          Length = 681

 Score = 1395 bits (3611), Expect = 0.0
 Identities = 681/681 (100%), Positives = 681/681 (100%)

Query: 1   MDIKHHQNGTRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLL 60
           MDIKHHQNGTRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLL
Sbjct: 1   MDIKHHQNGTRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLL 60

Query: 61  AIGLGAMGWGTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGPVANLRHNLNNVIA 120
           AIGLGAMGWGTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGPVANLRHNLNNVIA
Sbjct: 61  AIGLGAMGWGTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGPVANLRHNLNNVIA 120

Query: 121 SLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSKELLRAETRNISATFEDLDAQVNSET 180
           SLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSKELLRAETRNISATFEDLDAQVNSET
Sbjct: 121 SLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSKELLRAETRNISATFEDLDAQVNSET 180

Query: 181 GYTPEDTMDSGETAQGREARQAPASRLHLSTQKMYELKTKLRCSYVVNQAILSCRRWFDR 240
           GYTPEDTMDSGETAQGREARQAPASRLHLSTQKMYELKTKLRCSYVVNQAILSCRRWFDR
Sbjct: 181 GYTPEDTMDSGETAQGREARQAPASRLHLSTQKMYELKTKLRCSYVVNQAILSCRRWFDR 240

Query: 241 KHEQCMKHIWVPLLTHLLCLPMKFKFFCGIAKVMEVWCRNRIPVEGNFGQTYDSLNQSIR 300
           KHEQCMKHIWVPLLTHLLCLPMKFKFFCGIAKVMEVWCRNRIPVEGNFGQTYDSLNQSIR
Sbjct: 241 KHEQCMKHIWVPLLTHLLCLPMKFKFFCGIAKVMEVWCRNRIPVEGNFGQTYDSLNQSIR 300

Query: 301 GLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVRDYVYRQEARLEWALGLLHVLLSCTF 360
           GLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVRDYVYRQEARLEWALGLLHVLLSCTF
Sbjct: 301 GLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVRDYVYRQEARLEWALGLLHVLLSCTF 360

Query: 361 LLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPLRKAEEKTVIFPCK 420
           LLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPLRKAEEKTVIFPCK
Sbjct: 361 LLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPLRKAEEKTVIFPCK 420

Query: 421 PTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHHSFLQYSFRSSHKLEV 480
           PTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHHSFLQYSFRSSHKLEV
Sbjct: 421 PTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHHSFLQYSFRSSHKLEV 480

Query: 481 KVGGDSMLARLLRKTIGALNTSSETVMESNNMPCLPQPVGLDARAYWRAAVPIGLLVCLC 540
           KVGGDSMLARLLRKTIGALNTSSETVMESNNMPCLPQPVGLDARAYWRAAVPIGLLVCLC
Sbjct: 481 KVGGDSMLARLLRKTIGALNTSSETVMESNNMPCLPQPVGLDARAYWRAAVPIGLLVCLC 540

Query: 541 LLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRH 600
           LLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRH
Sbjct: 541 LLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRH 600

Query: 601 PLADILHRGCPLLRRWLCRRCVVCQAPETPESYVCRTLDCEAVYCWSCWDDMRQRCPVCT 660
           PLADILHRGCPLLRRWLCRRCVVCQAPETPESYVCRTLDCEAVYCWSCWDDMRQRCPVCT
Sbjct: 601 PLADILHRGCPLLRRWLCRRCVVCQAPETPESYVCRTLDCEAVYCWSCWDDMRQRCPVCT 660

Query: 661 PREELSSSAFSDSNDDTAYAG 681
           PREELSSSAFSDSNDDTAYAG
Sbjct: 661 PREELSSSAFSDSNDDTAYAG 681


>gi|219521924 DC-STAMP domain containing 1 isoform 1 [Homo sapiens]
          Length = 706

 Score = 1381 bits (3575), Expect = 0.0
 Identities = 681/706 (96%), Positives = 681/706 (96%), Gaps = 25/706 (3%)

Query: 1   MDIKHHQNGTRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLL 60
           MDIKHHQNGTRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLL
Sbjct: 1   MDIKHHQNGTRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLL 60

Query: 61  AIGL-------------------------GAMGWGTSPHIRCASLLLVPKMLGKEGRLFV 95
           AIGL                         GAMGWGTSPHIRCASLLLVPKMLGKEGRLFV
Sbjct: 61  AIGLFQLLVNPMNIYEEQKIMFLYSLVGLGAMGWGTSPHIRCASLLLVPKMLGKEGRLFV 120

Query: 96  LGYALAAIYVGPVANLRHNLNNVIASLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSK 155
           LGYALAAIYVGPVANLRHNLNNVIASLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSK
Sbjct: 121 LGYALAAIYVGPVANLRHNLNNVIASLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSK 180

Query: 156 ELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGREARQAPASRLHLSTQKMY 215
           ELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGREARQAPASRLHLSTQKMY
Sbjct: 181 ELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGREARQAPASRLHLSTQKMY 240

Query: 216 ELKTKLRCSYVVNQAILSCRRWFDRKHEQCMKHIWVPLLTHLLCLPMKFKFFCGIAKVME 275
           ELKTKLRCSYVVNQAILSCRRWFDRKHEQCMKHIWVPLLTHLLCLPMKFKFFCGIAKVME
Sbjct: 241 ELKTKLRCSYVVNQAILSCRRWFDRKHEQCMKHIWVPLLTHLLCLPMKFKFFCGIAKVME 300

Query: 276 VWCRNRIPVEGNFGQTYDSLNQSIRGLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVR 335
           VWCRNRIPVEGNFGQTYDSLNQSIRGLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVR
Sbjct: 301 VWCRNRIPVEGNFGQTYDSLNQSIRGLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVR 360

Query: 336 DYVYRQEARLEWALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDR 395
           DYVYRQEARLEWALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDR
Sbjct: 361 DYVYRQEARLEWALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDR 420

Query: 396 RKKLGKRTLLPLRKAEEKTVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWAL 455
           RKKLGKRTLLPLRKAEEKTVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWAL
Sbjct: 421 RKKLGKRTLLPLRKAEEKTVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWAL 480

Query: 456 YSIFDTIRHHSFLQYSFRSSHKLEVKVGGDSMLARLLRKTIGALNTSSETVMESNNMPCL 515
           YSIFDTIRHHSFLQYSFRSSHKLEVKVGGDSMLARLLRKTIGALNTSSETVMESNNMPCL
Sbjct: 481 YSIFDTIRHHSFLQYSFRSSHKLEVKVGGDSMLARLLRKTIGALNTSSETVMESNNMPCL 540

Query: 516 PQPVGLDARAYWRAAVPIGLLVCLCLLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLK 575
           PQPVGLDARAYWRAAVPIGLLVCLCLLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLK
Sbjct: 541 PQPVGLDARAYWRAAVPIGLLVCLCLLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLK 600

Query: 576 KRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCRRCVVCQAPETPESYVC 635
           KRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCRRCVVCQAPETPESYVC
Sbjct: 601 KRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCRRCVVCQAPETPESYVC 660

Query: 636 RTLDCEAVYCWSCWDDMRQRCPVCTPREELSSSAFSDSNDDTAYAG 681
           RTLDCEAVYCWSCWDDMRQRCPVCTPREELSSSAFSDSNDDTAYAG
Sbjct: 661 RTLDCEAVYCWSCWDDMRQRCPVCTPREELSSSAFSDSNDDTAYAG 706


>gi|109240536 DC-STAMP domain containing 2 [Homo sapiens]
          Length = 773

 Score =  167 bits (423), Expect = 3e-41
 Identities = 154/619 (24%), Positives = 254/619 (41%), Gaps = 43/619 (6%)

Query: 53  GAGAGGLLAIGLGAMGWGTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGPVANLR 112
           G   G L      ++G G S  +R   LLL+P+   ++GR  +L  A   +  GP AN  
Sbjct: 54  GCLVGTLTLAAFLSLGMGFSRQVRATVLLLLPQAFSRQGRTLLLVAAFGLVLQGPCANTL 113

Query: 113 HNLNNVIASLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSKELLRAETRNISATFEDL 172
            N      ++ C  EL +N T    + +  PL +    + +     +     +   F  +
Sbjct: 114 RNFTRASEAVACGAELALNQTAEVLQRAKQPLVSALNKIKAIARKTKEVADRVRKFFRSI 173

Query: 173 DAQVNSETGYTPEDTMDSGETAQGREARQAPASRLHLSTQKMYELKTKLRCSYVVNQAIL 232
                          MD G     R  R      LH+             C+  +    L
Sbjct: 174 ---------------MD-GVKHIARALRNVWQWLLHIGDV----------CNSELGNPYL 207

Query: 233 SCRRWFDRKHEQCMKHIWVPLLTHLLCLPMKFKF-FCGIAKVMEVWCRNRIPVEGNFGQT 291
            C R FD   + CM  + +P   HL  + M FK   CG+A +++V+C     ++    QT
Sbjct: 208 KCARVFDDAKDSCM--MVIPQAYHLCYVLMPFKLALCGLASLVQVFCVIPKYIQPFLRQT 265

Query: 292 YDS-LNQSIRGLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVRDYVYRQEARLEWALG 350
             + + Q +  +  EF  N+          L  + S  +V+ ++ + V  +  R+  AL 
Sbjct: 266 IGTPVIQLLNRVRQEFEFNMTATHHFSVD-LNASRSLSQVAMDLHEAVSMKLHRVREALA 324

Query: 351 LLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPLRKA 410
           L+        +L+   +  Y   Y +   +DNIYI++ F +++  R   G  T+LPL   
Sbjct: 325 LMGFTTPLLLVLLYLQALFYRYCYLNWDHYDNIYITSRFLRMEAVRSTAGLPTVLPLSAH 384

Query: 411 EEKTVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHHSFLQY 470
           E +  I P    +   E    + E    +  LLL++ L  LD+A++ + D  RH    + 
Sbjct: 385 EARRYIPPGSIFLSQWEKFFYILETFNLIRHLLLVLFLVFLDYAVFWVLDLARHQLQGEI 444

Query: 471 SFRSSHKLEVKVGGDSMLARLLRKTIGALNTSSETVMESNNMPCLPQPVGLDARAYWRAA 530
             RS   + + V G      + R  + A +   +  +   +  CL +P   D+  Y    
Sbjct: 445 VARSPVLVSLTVEGTGYAGNIYRDLVSAFDVLQQGNISILSRRCLLRPSEPDSTGYIVIG 504

Query: 531 VPIGLLVCLCLLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLKKRAAFTKLRRAAILR 590
           V  GL   + L  ++  RLRRVI A Y+P RE++RI +LYN LL +R         ++ R
Sbjct: 505 VMYGLCFFITLFGSYVSRLRRVICASYYPSREQERISYLYNVLLSRRTNLLAALHRSVRR 564

Query: 591 RERQQKAPRHPLADILHRGCPLL-----RRWLCRR-CVVCQAP----ETPESYVCRTLDC 640
           R   Q      L  +L   CP L       WL +  C+ C  P    +   +  C T  C
Sbjct: 565 RAADQGHRSAFL--VLASRCPCLGPFVSHFWLHQAYCLGCGQPQDEGDMENTVSCSTPGC 622

Query: 641 EAVYCWSCWDDMRQRCPVC 659
           + +YC +C+  +   C VC
Sbjct: 623 QGLYCLTCFRLLDNTCSVC 641


>gi|13540565 dendritic cell-specific transmembrane protein [Homo
           sapiens]
          Length = 470

 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 60/204 (29%), Positives = 105/204 (51%), Gaps = 19/204 (9%)

Query: 379 RFDNIYISTYFCQIDDRRKKLGKRTLLPLRKAEE-KTVIFPCK-PTIQASEMSNVVRELL 436
           +++NIYI+  F Q D+R +   +  +LPL K E  K VI P   PT    E  N+    L
Sbjct: 241 KYENIYITRQFVQFDERERHQQRPCVLPLNKEERRKYVIIPTFWPT--PKERKNLGLFFL 298

Query: 437 ETLPILLLLVVLCGLDWALYSIFDTIRHHSFLQYSFRSSHKLEVKVGGDSMLARLLRKTI 496
             L  L + V+   +D+ LY +  ++      Q+      ++ +K+ G+       + T 
Sbjct: 299 PILIHLCIWVLFAAVDYLLYRLIFSVSK----QFQSLPGFEVHLKLHGEK------QGTQ 348

Query: 497 GALNTSSE--TVMESNNMPCLPQPVGLDARAYWRAAVPIGLLVCLCLLQAFGYRLRRVIA 554
             ++ SS   +V E N   C+P+P  L +  +   +V + +LV L LL +   +L+ +++
Sbjct: 349 DIIHDSSFNISVFEPN---CIPKPKFLLSETWVPLSVILLILVMLGLLSSILMQLKILVS 405

Query: 555 AFYFPKREKKRILFLYNDLLKKRA 578
           A ++P  E+KRI +L+  LLKKR+
Sbjct: 406 ASFYPSVERKRIQYLHAKLLKKRS 429



 Score = 33.9 bits (76), Expect = 0.51
 Identities = 28/120 (23%), Positives = 49/120 (40%), Gaps = 13/120 (10%)

Query: 72  SPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGPVANLRHNLNNVIASLGCTVE---- 127
           S H RC  LL+      +EGR  ++      + +G V N+ HN   ++  + C +     
Sbjct: 75  SKHARCFILLVFLSCGLREGRNALIAAGTGIVILGHVENIFHNFKGLLDGMTCNLRAKSF 134

Query: 128 ------LQINNTRAAWRISTAPLRAMFKDLLSSKELLRAETRNISATFEDLDAQVNSETG 181
                 L+       W    A   ++F DL+S  + L     ++ +    L+AQ+N   G
Sbjct: 135 SIHFPLLKKYIEAIQWIYGLATPLSVFDDLVSWNQTLAV---SLFSPSHVLEAQLNDSKG 191


>gi|239757512 PREDICTED: chromosome 20 open reading frame 123 [Homo
           sapiens]
          Length = 560

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 92/357 (25%), Positives = 130/357 (36%), Gaps = 90/357 (25%)

Query: 348 ALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPL 407
           ALG   V+     L +L  S  Y+  Y  D+RFDNIY +    Q               L
Sbjct: 216 ALGTQRVVTGLFMLGLLVESAWYLHCYLTDLRFDNIYATQQLTQ--------------RL 261

Query: 408 RKAEEKTVIFPCKPT--IQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHH 465
            +A+   ++ P  PT  +QA+++     ELL  L  L LL +L        ++     H 
Sbjct: 262 AQAQATHLLAP-PPTWLLQAAQLRLSQEELLSCLLRLGLLALLL----VATAVAVATDHV 316

Query: 466 SFL--QYSFRSSHKLEVK--------------VGGDSMLARLLRKTIGALNTSS----ET 505
           +FL  Q +   + KL                 +G    L   L      L+  S    E 
Sbjct: 317 AFLLAQATVDWAQKLPTVPITLTVKYDVAYTVLGFIPFLFNQLAPESPFLSVHSSYQWEL 376

Query: 506 VMESNNMPCLPQPVGLDARAYWRAAVPI--GLLVCLC----LLQAFGYRLRRVIAAFYFP 559
            + S   P LP      AR   RAA P+  G L  L     LL+A+  RLR  IAA +F 
Sbjct: 377 RLTSARCPLLP------ARRP-RAAAPLAAGALQLLAGSTVLLEAYARRLRHAIAASFFT 429

Query: 560 KREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCR 619
            +E +R+  L+               A + RR  + +  + PL D     C    R  C+
Sbjct: 430 AQEARRVRHLH---------------ARLQRRHDRHQGQQLPLGD---PSCVPTPRPACK 471

Query: 620 RCVVCQAPETPESYVCRTLDC--------EAVYCWSCWDDMRQRCPVCTPREELSSS 668
                     P +++   LD         E    WSC D      PV  P   L  S
Sbjct: 472 ----------PPAWIDYRLDALRTESSEGEGKELWSCRDLSCNLGPVPPPCVTLGKS 518



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 50  LLLGAGAGGLLAIGLGAMGW---GTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVG 106
           LL   G   ++A   G + +   G  P +RC   L VP +  ++GR  +L Y+ A + + 
Sbjct: 68  LLYPPGPSAMVATVCGLLVFLSLGLVPPVRCLFALSVPTLGMEQGRRLLLSYSTATLAIA 127

Query: 107 PVANLRHNLNNVIASLGCTVE 127
            V N+  N+      L C  E
Sbjct: 128 VVPNVLANVGAAGQVLRCVTE 148


>gi|239752028 PREDICTED: hypothetical protein LOC128506 [Homo
           sapiens]
          Length = 560

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 92/357 (25%), Positives = 130/357 (36%), Gaps = 90/357 (25%)

Query: 348 ALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPL 407
           ALG   V+     L +L  S  Y+  Y  D+RFDNIY +    Q               L
Sbjct: 216 ALGTQRVVTGLFMLGLLVESAWYLHCYLTDLRFDNIYATQQLTQ--------------RL 261

Query: 408 RKAEEKTVIFPCKPT--IQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHH 465
            +A+   ++ P  PT  +QA+++     ELL  L  L LL +L        ++     H 
Sbjct: 262 AQAQATHLLAP-PPTWLLQAAQLRLSQEELLSCLLRLGLLALLL----VATAVAVATDHV 316

Query: 466 SFL--QYSFRSSHKLEVK--------------VGGDSMLARLLRKTIGALNTSS----ET 505
           +FL  Q +   + KL                 +G    L   L      L+  S    E 
Sbjct: 317 AFLLAQATVDWAQKLPTVPITLTVKYDVAYTVLGFIPFLFNQLAPESPFLSVHSSYQWEL 376

Query: 506 VMESNNMPCLPQPVGLDARAYWRAAVPI--GLLVCLC----LLQAFGYRLRRVIAAFYFP 559
            + S   P LP      AR   RAA P+  G L  L     LL+A+  RLR  IAA +F 
Sbjct: 377 RLTSARCPLLP------ARRP-RAAAPLAAGALQLLAGSTVLLEAYARRLRHAIAASFFT 429

Query: 560 KREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCR 619
            +E +R+  L+               A + RR  + +  + PL D     C    R  C+
Sbjct: 430 AQEARRVRHLH---------------ARLQRRHDRHQGQQLPLGD---PSCVPTPRPACK 471

Query: 620 RCVVCQAPETPESYVCRTLDC--------EAVYCWSCWDDMRQRCPVCTPREELSSS 668
                     P +++   LD         E    WSC D      PV  P   L  S
Sbjct: 472 ----------PPAWIDYRLDALRTESSEGEGKELWSCRDLSCNLGPVPPPCVTLGKS 518



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 50  LLLGAGAGGLLAIGLGAMGW---GTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVG 106
           LL   G   ++A   G + +   G  P +RC   L VP +  ++GR  +L Y+ A + + 
Sbjct: 68  LLYPPGPSAMVATVCGLLVFLSLGLVPPVRCLFALSVPTLGMEQGRRLLLSYSTATLAIA 127

Query: 107 PVANLRHNLNNVIASLGCTVE 127
            V N+  N+      L C  E
Sbjct: 128 VVPNVLANVGAAGQVLRCVTE 148


>gi|239746512 PREDICTED: hypothetical protein LOC128506 [Homo
           sapiens]
          Length = 560

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 92/357 (25%), Positives = 130/357 (36%), Gaps = 90/357 (25%)

Query: 348 ALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPL 407
           ALG   V+     L +L  S  Y+  Y  D+RFDNIY +    Q               L
Sbjct: 216 ALGTQRVVTGLFMLGLLVESAWYLHCYLTDLRFDNIYATQQLTQ--------------RL 261

Query: 408 RKAEEKTVIFPCKPT--IQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHH 465
            +A+   ++ P  PT  +QA+++     ELL  L  L LL +L        ++     H 
Sbjct: 262 AQAQATHLLAP-PPTWLLQAAQLRLSQEELLSCLLRLGLLALLL----VATAVAVATDHV 316

Query: 466 SFL--QYSFRSSHKLEVK--------------VGGDSMLARLLRKTIGALNTSS----ET 505
           +FL  Q +   + KL                 +G    L   L      L+  S    E 
Sbjct: 317 AFLLAQATVDWAQKLPTVPITLTVKYDVAYTVLGFIPFLFNQLAPESPFLSVHSSYQWEL 376

Query: 506 VMESNNMPCLPQPVGLDARAYWRAAVPI--GLLVCLC----LLQAFGYRLRRVIAAFYFP 559
            + S   P LP      AR   RAA P+  G L  L     LL+A+  RLR  IAA +F 
Sbjct: 377 RLTSARCPLLP------ARRP-RAAAPLAAGALQLLAGSTVLLEAYARRLRHAIAASFFT 429

Query: 560 KREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCR 619
            +E +R+  L+               A + RR  + +  + PL D     C    R  C+
Sbjct: 430 AQEARRVRHLH---------------ARLQRRHDRHQGQQLPLGD---PSCVPTPRPACK 471

Query: 620 RCVVCQAPETPESYVCRTLDC--------EAVYCWSCWDDMRQRCPVCTPREELSSS 668
                     P +++   LD         E    WSC D      PV  P   L  S
Sbjct: 472 ----------PPAWIDYRLDALRTESSEGEGKELWSCRDLSCNLGPVPPPCVTLGKS 518



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 50  LLLGAGAGGLLAIGLGAMGW---GTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVG 106
           LL   G   ++A   G + +   G  P +RC   L VP +  ++GR  +L Y+ A + + 
Sbjct: 68  LLYPPGPSAMVATVCGLLVFLSLGLVPPVRCLFALSVPTLGMEQGRRLLLSYSTATLAIA 127

Query: 107 PVANLRHNLNNVIASLGCTVE 127
            V N+  N+      L C  E
Sbjct: 128 VVPNVLANVGAAGQVLRCVTE 148


>gi|225637556 hypothetical protein LOC128506 [Homo sapiens]
          Length = 566

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 92/357 (25%), Positives = 130/357 (36%), Gaps = 90/357 (25%)

Query: 348 ALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPL 407
           ALG   V+     L +L  S  Y+  Y  D+RFDNIY +    Q               L
Sbjct: 222 ALGTQRVVTGLFMLGLLVESAWYLHCYLTDLRFDNIYATQQLTQ--------------RL 267

Query: 408 RKAEEKTVIFPCKPT--IQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHH 465
            +A+   ++ P  PT  +QA+++     ELL  L  L LL +L        ++     H 
Sbjct: 268 AQAQATHLLAP-PPTWLLQAAQLRLSQEELLSCLLRLGLLALLL----VATAVAVATDHV 322

Query: 466 SFL--QYSFRSSHKLEVK--------------VGGDSMLARLLRKTIGALNTSS----ET 505
           +FL  Q +   + KL                 +G    L   L      L+  S    E 
Sbjct: 323 AFLLAQATVDWAQKLPTVPITLTVKYDVAYTVLGFIPFLFNQLAPESPFLSVHSSYQWEL 382

Query: 506 VMESNNMPCLPQPVGLDARAYWRAAVPI--GLLVCLC----LLQAFGYRLRRVIAAFYFP 559
            + S   P LP      AR   RAA P+  G L  L     LL+A+  RLR  IAA +F 
Sbjct: 383 RLTSARCPLLP------ARRP-RAAAPLAAGALQLLAGSTVLLEAYARRLRHAIAASFFT 435

Query: 560 KREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCR 619
            +E +R+  L+               A + RR  + +  + PL D     C    R  C+
Sbjct: 436 AQEARRVRHLH---------------ARLQRRHDRHQGQQLPLGD---PSCVPTPRPACK 477

Query: 620 RCVVCQAPETPESYVCRTLDC--------EAVYCWSCWDDMRQRCPVCTPREELSSS 668
                     P +++   LD         E    WSC D      PV  P   L  S
Sbjct: 478 ----------PPAWIDYRLDALRTESSEGEGKELWSCRDLSCNLGPVPPPCVTLGKS 524



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 50  LLLGAGAGGLLAIGLGAMGW---GTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVG 106
           LL   G   ++A   G + +   G  P +RC   L VP +  ++GR  +L Y+ A + + 
Sbjct: 74  LLYPPGPSAMVATVCGLLVFLSLGLVPPVRCLFALSVPTLGMEQGRRLLLSYSTATLAIA 133

Query: 107 PVANLRHNLNNVIASLGCTVE 127
            V N+  N+      L C  E
Sbjct: 134 VVPNVLANVGAAGQVLRCVTE 154


>gi|239757412 PREDICTED: hypothetical protein XP_002345272 [Homo
           sapiens]
          Length = 564

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 9/54 (16%)

Query: 611 PLLRRWLCRRCVVCQA--PETPESYVCRTLDCEAVYCWSCWDDMRQRCPVCTPR 662
           P+  RW CRR V+C    P+TP+         + +     W  M+ R PVCT R
Sbjct: 409 PVCTRWCCRRLVLCVKLFPQTPQW-------DDHLKARPHWPQMKARRPVCTLR 455


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 18/46 (39%), Positives = 20/46 (43%), Gaps = 9/46 (19%)

Query: 616  WLCRRCVVCQAPETPESYVCRTLDC---EAVYCWSCWDDMRQRCPV 658
            WL   C  C    TPE  +C   +C   EA   WS W D    CPV
Sbjct: 4228 WLQGECQRCSC--TPEGVICEDTECAVPEAWTLWSSWSD----CPV 4267


>gi|7657522 ring finger protein 7 isoform 1 [Homo sapiens]
          Length = 113

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 16/53 (30%), Positives = 22/53 (41%), Gaps = 3/53 (5%)

Query: 610 CPLLRRWLCRRCVVCQAPETPESYVCRTLDCEAVY---CWSCWDDMRQRCPVC 659
           C + R  +   C+ CQA    E  V    +C   +   C S W     RCP+C
Sbjct: 50  CAICRVQVMDACLRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLC 102


>gi|109134327 PTD016 protein [Homo sapiens]
          Length = 435

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 3/40 (7%)

Query: 621 CVVCQAP-ETPESYVCRTLDCEAVYCWSCWDDMRQRCPVC 659
           C +CQA  + P   +C+ + CE   C + W +  + CP+C
Sbjct: 375 CSICQAEFQKPILLICQHIFCEE--CMTLWFNREKTCPLC 412


>gi|219555718 synaptonemal complex central element protein 1 isoform
           4 [Homo sapiens]
          Length = 351

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 18/47 (38%), Positives = 25/47 (53%)

Query: 153 SSKELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGREA 199
           SSKE L  E + + AT ED+  Q+ S  G     T+D G   + +EA
Sbjct: 190 SSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEA 236


>gi|219555716 synaptonemal complex central element protein 1 isoform
           3 [Homo sapiens]
          Length = 318

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 18/47 (38%), Positives = 25/47 (53%)

Query: 153 SSKELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGREA 199
           SSKE L  E + + AT ED+  Q+ S  G     T+D G   + +EA
Sbjct: 190 SSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEA 236


>gi|18640754 synaptonemal complex central element protein 1 isoform
           1 [Homo sapiens]
          Length = 282

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 18/47 (38%), Positives = 25/47 (53%)

Query: 153 SSKELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGREA 199
           SSKE L  E + + AT ED+  Q+ S  G     T+D G   + +EA
Sbjct: 154 SSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEA 200


>gi|158186614 transmembrane protein 118 isoform 1 [Homo sapiens]
          Length = 444

 Score = 30.8 bits (68), Expect = 4.3
 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 621 CVVCQAP-ETPESYVCRTLDCEAVYCWSCWDDMRQRCPVC 659
           C +CQA    P   +C+ + CE   C   W D  + CP+C
Sbjct: 384 CAICQAEFREPLILLCQHVFCEECLC--LWLDRERTCPLC 421


>gi|239746366 PREDICTED: hypothetical protein XP_002343738 [Homo
           sapiens]
          Length = 522

 Score = 30.4 bits (67), Expect = 5.6
 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 2/46 (4%)

Query: 611 PLLRRWLCRRCVVCQ--APETPESYVCRTLDCEAVYCWSCWDDMRQ 654
           P+  RW CRR  VC    P+TP+++    +      C   W   R+
Sbjct: 329 PVCTRWCCRRLEVCAKLLPQTPQAWGLSPVKARRPVCTRWWMASRE 374


>gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo
            sapiens]
          Length = 1977

 Score = 30.4 bits (67), Expect = 5.6
 Identities = 21/105 (20%), Positives = 46/105 (43%), Gaps = 6/105 (5%)

Query: 359  TFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDR-----RKKLGKRTLLPLRKAEEK 413
            T++ +L     ++ +Y +   F N +    F  +D          LG   L P++     
Sbjct: 1223 TYIFILEMLLKWI-AYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTL 1281

Query: 414  TVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSI 458
              + P +   +   M  VV  L+  +P ++ ++++C + W ++SI
Sbjct: 1282 RALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSI 1326


>gi|4504713 insulinoma-associated 1 [Homo sapiens]
          Length = 510

 Score = 30.4 bits (67), Expect = 5.6
 Identities = 33/94 (35%), Positives = 35/94 (37%), Gaps = 16/94 (17%)

Query: 14  RRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLLAIGLGAMGWGTSP 73
           R  + H   +R    G PVS           FP  A LLG G GG      GA G G   
Sbjct: 108 REHEKHKYFERSFNLGSPVSAE--------SFPTPAALLGGGGGG------GASGAGGGG 153

Query: 74  HIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGP 107
                 LL  P  L K G  F  G A AA   GP
Sbjct: 154 TCGGDPLLFAPAEL-KMGTAFSAG-AEAARGPGP 185


>gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapiens]
          Length = 1836

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 21/105 (20%), Positives = 46/105 (43%), Gaps = 6/105 (5%)

Query: 359  TFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDR-----RKKLGKRTLLPLRKAEEK 413
            T++ ++     ++ +Y   + F N +    F  +D          LG   L P++     
Sbjct: 1073 TYIFIMEMLLKWV-AYGFKVYFTNAWCWLDFLIVDVSIISLVANWLGYSELGPIKSLRTL 1131

Query: 414  TVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSI 458
              + P +   +   M  VV  LL  +P ++ ++++C + W ++SI
Sbjct: 1132 RALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSI 1176


>gi|21361493 ring finger protein 141 [Homo sapiens]
          Length = 230

 Score = 30.0 bits (66), Expect = 7.4
 Identities = 32/150 (21%), Positives = 56/150 (37%), Gaps = 35/150 (23%)

Query: 520 GLDARAYWRAAVPIGLLVCLCLLQAFGY-RLRRVIAAFYFPKREKKRILFLYNDLLKKRA 578
           G D+ A+W+  V +   VC  + ++ G     R++  + F        + LY D+  + A
Sbjct: 67  GSDSSAFWKVVVRV---VCTKINKSSGIVEASRIMNLYQF--------IQLYKDITSQAA 115

Query: 579 AFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCRRCVVCQAPETPESYVCRT- 637
                    +L +    + P    + +      L   W+ R   V Q  +  E  +C   
Sbjct: 116 G--------VLAQSSTSEEPDENSSSVTSCQASL---WMGR---VKQLTDEEECCICMDG 161

Query: 638 -----LDCEAVYCWSC---WDDMRQRCPVC 659
                L C   +C  C   W D  + CP+C
Sbjct: 162 RADLILPCAHSFCQKCIDKWSDRHRNCPIC 191


>gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1
           [Homo sapiens]
          Length = 352

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 7/80 (8%)

Query: 583 LRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCRRCVVCQAPETPESYVCRTLDCEA 642
           L+R   LR ++ Q+  +   A +L R  P  R  L   CVVC +        C  L+C  
Sbjct: 264 LQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLS----SFKSCVFLECGH 319

Query: 643 V-YCWSCWDDMRQ--RCPVC 659
           V  C  C+  + +  +CP+C
Sbjct: 320 VCSCTECYRALPEPKKCPIC 339


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 17/73 (23%), Positives = 43/73 (58%), Gaps = 2/73 (2%)

Query: 149 KDLLSSKELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGR-EARQAPASRL 207
           +DLL +K+  + +++ +S+    +  +++  +  + E+T D G+    +  ++++ +S+L
Sbjct: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179

Query: 208 HL-STQKMYELKT 219
           H   T+K  ELK+
Sbjct: 180 HKEKTRKERELKS 192


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 17/73 (23%), Positives = 43/73 (58%), Gaps = 2/73 (2%)

Query: 149 KDLLSSKELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGR-EARQAPASRL 207
           +DLL +K+  + +++ +S+    +  +++  +  + E+T D G+    +  ++++ +S+L
Sbjct: 120 RDLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKL 179

Query: 208 HL-STQKMYELKT 219
           H   T+K  ELK+
Sbjct: 180 HKEKTRKERELKS 192


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,093,641
Number of Sequences: 37866
Number of extensions: 1179574
Number of successful extensions: 3692
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3657
Number of HSP's gapped (non-prelim): 44
length of query: 681
length of database: 18,247,518
effective HSP length: 109
effective length of query: 572
effective length of database: 14,120,124
effective search space: 8076710928
effective search space used: 8076710928
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.