Guide to the Human Genome
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Search of human proteins with 218563746

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|218563746 hypothetical protein LOC401124 [Homo sapiens]
         (616 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|218563746 hypothetical protein LOC401124 [Homo sapiens]           1241   0.0  
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]                        62   2e-09
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]                         62   2e-09
gi|32967599 ankyrin 3 isoform 2 [Homo sapiens]                         60   6e-09
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         55   2e-07
gi|61742786 leucine rich repeat and death domain containing prot...    55   2e-07
gi|61742784 leucine rich repeat and death domain containing prot...    54   3e-07
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         49   1e-05
gi|61742782 leucine rich repeat and death domain containing prot...    49   1e-05
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]                        45   2e-04
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         45   2e-04
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         45   2e-04
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]                         45   2e-04
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]                         45   2e-04
gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]            32   2.3  
gi|31543630 solute carrier family 20 (phosphate transporter), me...    31   2.9  
gi|158341646 hypothetical protein LOC729830 [Homo sapiens]             30   5.0  
gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]           30   6.6  
gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens]           30   6.6  
gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]           30   6.6  
gi|4505725 peroxin1 [Homo sapiens]                                     30   6.6  
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]     30   8.6  
gi|13128864 histone deacetylase 6 [Homo sapiens]                       30   8.6  
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]        30   8.6  
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]        30   8.6  

>gi|218563746 hypothetical protein LOC401124 [Homo sapiens]
          Length = 616

 Score = 1241 bits (3212), Expect = 0.0
 Identities = 616/616 (100%), Positives = 616/616 (100%)

Query: 1   MCLEKRYLDVLSDVTGPQVSCYITAPSYVLQQLECRIINHMSSLIVGDNEELVSNVITIE 60
           MCLEKRYLDVLSDVTGPQVSCYITAPSYVLQQLECRIINHMSSLIVGDNEELVSNVITIE
Sbjct: 1   MCLEKRYLDVLSDVTGPQVSCYITAPSYVLQQLECRIINHMSSLIVGDNEELVSNVITIE 60

Query: 61  CSDKEKRVPFPIGIAIPFTARYRGNYRDIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCA 120
           CSDKEKRVPFPIGIAIPFTARYRGNYRDIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCA
Sbjct: 61  CSDKEKRVPFPIGIAIPFTARYRGNYRDIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCA 120

Query: 121 SVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPV 180
           SVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPV
Sbjct: 121 SVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPV 180

Query: 181 DPALVAHLKAQQDTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPCSPYLDKNNLGSEIDH 240
           DPALVAHLKAQQDTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPCSPYLDKNNLGSEIDH
Sbjct: 181 DPALVAHLKAQQDTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPCSPYLDKNNLGSEIDH 240

Query: 241 KRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSG 300
           KRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSG
Sbjct: 241 KRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSG 300

Query: 301 LVSVELYEHLERFIVLHLSSTMDNSHLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVL 360
           LVSVELYEHLERFIVLHLSSTMDNSHLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVL
Sbjct: 301 LVSVELYEHLERFIVLHLSSTMDNSHLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVL 360

Query: 361 VVPSKDLSQVLKDLHLEGFGGPPEPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTL 420
           VVPSKDLSQVLKDLHLEGFGGPPEPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTL
Sbjct: 361 VVPSKDLSQVLKDLHLEGFGGPPEPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTL 420

Query: 421 IFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVVYKVPKGKIVPNLNQSLVINENHSQLP 480
           IFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVVYKVPKGKIVPNLNQSLVINENHSQLP
Sbjct: 421 IFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVVYKVPKGKIVPNLNQSLVINENHSQLP 480

Query: 481 ICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWDNLLHWLAEELSEENAESLSSTLPLRR 540
           ICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWDNLLHWLAEELSEENAESLSSTLPLRR
Sbjct: 481 ICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWDNLLHWLAEELSEENAESLSSTLPLRR 540

Query: 541 STIQLIKLKNPDDLTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEELKFKWE 600
           STIQLIKLKNPDDLTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEELKFKWE
Sbjct: 541 STIQLIKLKNPDDLTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEELKFKWE 600

Query: 601 NKVFTEPQQCFDVAPE 616
           NKVFTEPQQCFDVAPE
Sbjct: 601 NKVFTEPQQCFDVAPE 616


>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
          Length = 1863

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 127/588 (21%), Positives = 231/588 (39%), Gaps = 104/588 (17%)

Query: 46   VGDNEELVSNVITIECSDKEKRVPFPIGIAIPFTARYRGNYRDIMV-----------KVC 94
            + + E LVS ++ +       +   P+ + IP  A  RG  R+++V             C
Sbjct: 1044 LNEGESLVSRILQL--GPPGTKFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFC 1101

Query: 95   D---------INLQSSYLN-PNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVT 144
            D         +N     L+ P  LE      K  C  +       F+VVS +K++S  + 
Sbjct: 1102 DYTEDELNEILNGMDEVLDSPEDLEK-----KRICRIITRDFPQYFAVVSRIKQDSNLIG 1156

Query: 145  KKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQSTSPL 204
             +G  L S++  ++   +P G  T  + V L+ QP+   LV  +   + TF      SP+
Sbjct: 1157 PEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATF------SPI 1210

Query: 205  IHIQHPSTYPFQKPVTLFLP---CSPYLDKNNLGSEIDHKRRASATINRITPSYFNRTKI 261
            + ++ P    F KP+T+ +P    S  +  N  G +    R   +     TP+ +     
Sbjct: 1211 VTLE-PRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITG 1269

Query: 262  ASIRKPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSGLVSVELYEHLERFIVLHLSST 321
             +   P    +EC   + F +  S    L D  +  +S   + ++Y   E   V +++  
Sbjct: 1270 TT---PLTFVNEC---VSFTTNVSARFWLIDCRQIQESVTFASQVYR--EIICVPYMAK- 1320

Query: 322  MDNSHLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGG 381
                  V F KS  + + +   C  ++  K     +   +   ++ ++V +         
Sbjct: 1321 -----FVVFAKS-HDPIEARLRCFCMTDDK-----VDKTLEQQENFAEVAR--------- 1360

Query: 382  PPEPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFHLQRKPRLELQIKEVDEFG 441
                SR  +V EG+ + +   GN+   +     G+ +   F   ++ RL L +K V +  
Sbjct: 1361 ----SRDVEVLEGKPIYVDCFGNLVPLTKS---GQHHIFSFFAFKENRLPLFVK-VRDTT 1412

Query: 442  NYSCPHYKGTIVVYKVPKGKIVPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQ-- 499
               C    G +   K PK        + LV         IC L + LP + K     Q  
Sbjct: 1413 QEPC----GRLSFMKEPKS------TRGLV------HQAICNLNITLPIYTKESESDQEQ 1456

Query: 500  ------STKRVSKDPVEALWDNLLHWLAEELSEENAESLSSTLPLRRSTIQLIKLKNPDD 553
                  ++++  +D  E + +  L ++A+ L     E L+  L      I  I+++NP+ 
Sbjct: 1457 EEEIDMTSEKNPQDEQERI-EERLAYIADHLGFSWTE-LARELDFTEEQIHQIRIENPNS 1514

Query: 554  LTEQIHEFLCFW-KKSLPTFTDKLRLLARHLRKIGRSDLAEELKFKWE 600
            L +Q H  L +W ++     TD    L   L KI R D+   ++   E
Sbjct: 1515 LQDQSHALLKYWLERDGKHATD--TNLVECLTKINRMDIVHLMETNTE 1560


>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 127/588 (21%), Positives = 231/588 (39%), Gaps = 104/588 (17%)

Query: 46   VGDNEELVSNVITIECSDKEKRVPFPIGIAIPFTARYRGNYRDIMV-----------KVC 94
            + + E LVS ++ +       +   P+ + IP  A  RG  R+++V             C
Sbjct: 1053 LNEGESLVSRILQL--GPPGTKFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFC 1110

Query: 95   D---------INLQSSYLN-PNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVT 144
            D         +N     L+ P  LE      K  C  +       F+VVS +K++S  + 
Sbjct: 1111 DYTEDELNEILNGMDEVLDSPEDLEK-----KRICRIITRDFPQYFAVVSRIKQDSNLIG 1165

Query: 145  KKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQSTSPL 204
             +G  L S++  ++   +P G  T  + V L+ QP+   LV  +   + TF      SP+
Sbjct: 1166 PEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATF------SPI 1219

Query: 205  IHIQHPSTYPFQKPVTLFLP---CSPYLDKNNLGSEIDHKRRASATINRITPSYFNRTKI 261
            + ++ P    F KP+T+ +P    S  +  N  G +    R   +     TP+ +     
Sbjct: 1220 VTLE-PRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITG 1278

Query: 262  ASIRKPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSGLVSVELYEHLERFIVLHLSST 321
             +   P    +EC   + F +  S    L D  +  +S   + ++Y   E   V +++  
Sbjct: 1279 TT---PLTFVNEC---VSFTTNVSARFWLIDCRQIQESVTFASQVYR--EIICVPYMAK- 1329

Query: 322  MDNSHLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGG 381
                  V F KS  + + +   C  ++  K     +   +   ++ ++V +         
Sbjct: 1330 -----FVVFAKS-HDPIEARLRCFCMTDDK-----VDKTLEQQENFAEVAR--------- 1369

Query: 382  PPEPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFHLQRKPRLELQIKEVDEFG 441
                SR  +V EG+ + +   GN+   +     G+ +   F   ++ RL L +K V +  
Sbjct: 1370 ----SRDVEVLEGKPIYVDCFGNLVPLTKS---GQHHIFSFFAFKENRLPLFVK-VRDTT 1421

Query: 442  NYSCPHYKGTIVVYKVPKGKIVPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQ-- 499
               C    G +   K PK        + LV         IC L + LP + K     Q  
Sbjct: 1422 QEPC----GRLSFMKEPKS------TRGLV------HQAICNLNITLPIYTKESESDQEQ 1465

Query: 500  ------STKRVSKDPVEALWDNLLHWLAEELSEENAESLSSTLPLRRSTIQLIKLKNPDD 553
                  ++++  +D  E + +  L ++A+ L     E L+  L      I  I+++NP+ 
Sbjct: 1466 EEEIDMTSEKNPQDEQERI-EERLAYIADHLGFSWTE-LARELDFTEEQIHQIRIENPNS 1523

Query: 554  LTEQIHEFLCFW-KKSLPTFTDKLRLLARHLRKIGRSDLAEELKFKWE 600
            L +Q H  L +W ++     TD    L   L KI R D+   ++   E
Sbjct: 1524 LQDQSHALLKYWLERDGKHATD--TNLVECLTKINRMDIVHLMETNTE 1569


>gi|32967599 ankyrin 3 isoform 2 [Homo sapiens]
          Length = 1001

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 117/517 (22%), Positives = 200/517 (38%), Gaps = 106/517 (20%)

Query: 130 FSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLK 189
           F+VVS +K+ES  +  +G  L S+    +  ++P G  T  + V L+ QPV   +V  + 
Sbjct: 268 FAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKIL 327

Query: 190 AQQDTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPCSPYLDKNNLGSEIDHKRRASATIN 249
             + TF      SP++ ++ P    F KP+T+ +P  P       G  + +  +   T N
Sbjct: 328 GNKATF------SPIVTVE-PRRRKFHKPITMTIPVPP-----PSGEGVSNGYKGDTTPN 375

Query: 250 -RITPSYFNRTKIASIR-----KPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSGLVS 303
            R+  S    T  A         P     +C   + F +  S    L D  + +++  ++
Sbjct: 376 LRLLCSITGGTSPAQWEDITGTTPLTFIKDC---VSFTTNVSARFWLADCHQVLETVGLA 432

Query: 304 VELYEHLERFIVLHLSSTMDNSHLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVP 363
            +LY  L    V +++        V F K + + + S+  C  ++  K     +   +  
Sbjct: 433 TQLYREL--ICVPYMAK------FVVFAK-MNDPVESSLRCFCMTDDK-----VDKTLEQ 478

Query: 364 SKDLSQVLKDLHLEGFGGPPEPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFH 423
            ++  +V +             S+  +V EG+ + +   GN+   + G   G+     F+
Sbjct: 479 QENFEEVAR-------------SKDIEVLEGKPIYVDCYGNLAPLTKG---GQQLVFNFY 522

Query: 424 LQRKPRLELQIKEVDEFGNYSCPHYKGTIVVYKVPKGKIVPNLNQSLVINENHSQLPICK 483
             ++ RL   IK + +     C    G +   K PK              +   Q  +C 
Sbjct: 523 SFKENRLPFSIK-IRDTSQEPC----GRLSFLKEPK------------TTKGLPQTAVCN 565

Query: 484 LPLKLPKHKKL--INRPQS------TKRVS---------KDPVEALWDNLLHWLAEELSE 526
           L + LP HKK+   +R QS       KR S         + P E   D  +  +A+ L  
Sbjct: 566 LNITLPAHKKIEKTDRRQSFASLALRKRYSYLTEPGMSPQSPCERT-DIRMAIVADHLGL 624

Query: 527 ENAESLSSTLPLRRSTIQLIKLKNPDDLTEQIHEFLCFW--KKSLPTFTDKLRLLARHLR 584
              E L+  L      I  I+++NP+ L  Q    L  W  +      TD L  +   L 
Sbjct: 625 SWTE-LARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALTSV---LT 680

Query: 585 KIGRSDLAEELK--------------FKWENKVFTEP 607
           KI R D+   L+              F  EN VF +P
Sbjct: 681 KINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDP 717


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 80/370 (21%), Positives = 147/370 (39%), Gaps = 68/370 (18%)

Query: 130  FSVVSCLKKESFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLK 189
            F+VVS +K+ES  +  +G  L S+    +  ++P G  T  + V L+ QPV   +V  + 
Sbjct: 1134 FAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPDEIVKKIL 1193

Query: 190  AQQDTFYSVQSTSPLIHIQHPSTYPFQKPVTLFLPCSPYLDKNNLGSEIDHKRRASATIN 249
              + TF      SP++ ++ P    F KP+T+ +P  P       G  + +  +   T N
Sbjct: 1194 GNKATF------SPIVTVE-PRRRKFHKPITMTIPVPP-----PSGEGVSNGYKGDTTPN 1241

Query: 250  -RITPSYFNRTKIASIR-----KPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSGLVS 303
             R+  S    T  A         P     +C   + F +  S    L D  + +++  ++
Sbjct: 1242 LRLLCSITGGTSPAQWEDITGTTPLTFIKDC---VSFTTNVSARFWLADCHQVLETVGLA 1298

Query: 304  VELYEHLERFIVLHLSSTMDNSHLVTFVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVP 363
             +LY  L    V +++        V F K + + + S+  C  ++  K     +   +  
Sbjct: 1299 TQLYREL--ICVPYMAK------FVVFAK-MNDPVESSLRCFCMTDDK-----VDKTLEQ 1344

Query: 364  SKDLSQVLKDLHLEGFGGPPEPSRHFQVREGEQLLLRFTGNIFASSNGKDYGKDYTLIFH 423
             ++  +V +             S+  +V EG+ + +   GN+   + G   G+     F+
Sbjct: 1345 QENFEEVAR-------------SKDIEVLEGKPIYVDCYGNLAPLTKG---GQQLVFNFY 1388

Query: 424  LQRKPRLELQIKEVDEFGNYSCPHYKGTIVVYKVPKGKIVPNLNQSLVINENHSQLPICK 483
              ++ RL   IK + +     C    G +   K PK              +   Q  +C 
Sbjct: 1389 SFKENRLPFSIK-IRDTSQEPC----GRLSFLKEPK------------TTKGLPQTAVCN 1431

Query: 484  LPLKLPKHKK 493
            L + LP HKK
Sbjct: 1432 LNITLPAHKK 1441


>gi|61742786 leucine rich repeat and death domain containing protein
           isoform 3 [Homo sapiens]
          Length = 893

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 127/573 (22%), Positives = 216/573 (37%), Gaps = 111/573 (19%)

Query: 46  VGDNEELVSNVITIECSDKEKRVPFP--IGIAIPFTARYRGNYRDIMVKVCDINLQS--- 100
           +G ++ L+S+V+ ++       V F   +G+ + FT       R+++V+  + N      
Sbjct: 370 LGPHDALLSHVLELQ----PHGVAFQQDVGLWLLFTPPQARRCREVVVRTRNDNSWGDLE 425

Query: 101 SYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISL 160
           +YL   + + +        A  +V     F VVS     +  V  +G  L SS    + +
Sbjct: 426 TYLEEEAPQRL-------WAHCQVPHFSWFLVVSRPVSNACLVPPEGTLLCSSGHPGVKV 478

Query: 161 NYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQSTSPLIHIQHPSTYPFQKPVT 220
            +PPG    P  V +++  +    +  L  + +      + SPL+ +       F +PVT
Sbjct: 479 IFPPGATEEPRRVSMQVVRMAGRELQALLGEPEA-----AVSPLLCLSQSGPPSFLQPVT 533

Query: 221 LFLPCSPYLDKNNLGSEIDHKRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGF 280
           + LP    L     G  +D  R                                L LL +
Sbjct: 534 VQLP----LPSGITGLSLDRSR--------------------------------LHLLYW 557

Query: 281 RSQDSGWCGLDDVVKTIQSGLVSVELYEHLERFIVLHLS-----STMDNSHLVTFVKSLE 335
               + W   DD+     +  V +EL     RF V H S      T  N       K+ E
Sbjct: 558 APPAATW---DDI-----TAQVVLELTHLYARFQVTHFSWYWLWYTTKNCVGGLARKAWE 609

Query: 336 EAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGGPPEPSRHFQVREGE 395
              L     I L  ++D P ++ +  +P   +   L+ L LE + GP EPS   ++ EGE
Sbjct: 610 RLRLHRVNLIALQRRRD-PEQVLLQCLPRNKVDATLRRL-LERYRGP-EPSDTVEMFEGE 666

Query: 396 QLLLRFTGNIFASSNGKDYGKD-YTLIFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVV 454
           +    F   I   ++  D  +     +F+   K      +KEV          Y+G + V
Sbjct: 667 EFFAAFERGIDVDADRPDCVEGRICFVFYSHLK-----NVKEVS--------FYRGAVPV 713

Query: 455 YKVPKGKIVPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWD 514
                   VP   ++    +    L +  LP+KLP+ +     P+    +S  P+     
Sbjct: 714 R-------VPEEAEAARQRKGADALWMATLPIKLPRLRGS-EGPRRGAGLSLAPL----- 760

Query: 515 NLLHWLAEELSEENAESLSSTLPL-----------RRSTIQLIKLKNPDDLTEQIHEFLC 563
           NL       L++ N  S++  L L               +Q I+ +  DDL EQI   L 
Sbjct: 761 NLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLF 820

Query: 564 FWKKSLPTFTDKLRLLARHLRKIGRSDLAEELK 596
            W +        + LL + L +  R D+AEE++
Sbjct: 821 SWAERQAGQPGAVGLLVQALEQSDRQDVAEEVR 853


>gi|61742784 leucine rich repeat and death domain containing protein
           isoform 1 [Homo sapiens]
          Length = 910

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 124/573 (21%), Positives = 216/573 (37%), Gaps = 94/573 (16%)

Query: 46  VGDNEELVSNVITIECSDKEKRVPFP--IGIAIPFTARYRGNYRDIMVKVCDINLQS--- 100
           +G ++ L+S+V+ ++       V F   +G+ + FT       R+++V+  + N      
Sbjct: 370 LGPHDALLSHVLELQ----PHGVAFQQDVGLWLLFTPPQARRCREVVVRTRNDNSWGDLE 425

Query: 101 SYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISL 160
           +YL   + + +        A  +V     F VVS     +  V  +G  L SS    + +
Sbjct: 426 TYLEEEAPQRL-------WAHCQVPHFSWFLVVSRPVSNACLVPPEGTLLCSSGHPGVKV 478

Query: 161 NYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQSTSPLIHIQHPSTYPFQKPVT 220
            +PPG    P  V +++  +    +  L  + +      + SPL+ +       F +PVT
Sbjct: 479 IFPPGATEEPRRVSMQVVRMAGRELQALLGEPEA-----AVSPLLCLSQSGPPSFLQPVT 533

Query: 221 LFLPCSPYLDKNNLGSEIDHKRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGF 280
           + LP    L     G  +D  R                                L LL +
Sbjct: 534 VQLP----LPSGITGLSLDRSR--------------------------------LHLLYW 557

Query: 281 RSQDSGWCGLDDVVKTIQSGLVSVELYEHLERFIVLHLS-----STMDNSHLVTFVKSLE 335
               + W   DD+     +  V +EL     RF V H S      T  N       K+ E
Sbjct: 558 APPAATW---DDI-----TAQVVLELTHLYARFQVTHFSWYWLWYTTKNCVGGLARKAWE 609

Query: 336 EAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGGPPEPSRHFQVREGE 395
              L     I L  ++D P ++ +  +P   +   L+ L LE + GP EPS   ++ EGE
Sbjct: 610 RLRLHRVNLIALQRRRD-PEQVLLQCLPRNKVDATLRRL-LERYRGP-EPSDTVEMFEGE 666

Query: 396 QLLLRFTGNIFASSNGKDYGKD-YTLIFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVV 454
           +    F   I   ++  D  +     +F+   K   E+ +    +         +G +  
Sbjct: 667 EFFAAFERGIDVDADRPDCVEGRICFVFYSHLKNVKEVYVTTTLD---REAQAVRGQVSF 723

Query: 455 YKVPKGKIVPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWD 514
           Y+      VP   ++    +    L +  LP+KLP+ +     P+    +S  P+     
Sbjct: 724 YRGAVPVRVPEEAEAARQRKGADALWMATLPIKLPRLRGS-EGPRRGAGLSLAPL----- 777

Query: 515 NLLHWLAEELSEENAESLSSTLPL-----------RRSTIQLIKLKNPDDLTEQIHEFLC 563
           NL       L++ N  S++  L L               +Q I+ +  DDL EQI   L 
Sbjct: 778 NLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLF 837

Query: 564 FWKKSLPTFTDKLRLLARHLRKIGRSDLAEELK 596
            W +        + LL + L +  R D+AEE++
Sbjct: 838 SWAERQAGQPGAVGLLVQALEQSDRQDVAEEVR 870


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 49/200 (24%), Positives = 86/200 (43%), Gaps = 35/200 (17%)

Query: 46   VGDNEELVSNVITIECSDKEKRVPFPIGIAIPFTARYRGNYRDIMV-----------KVC 94
            + + E LVS ++ +       +   P+ + IP  A  RG  R+++V             C
Sbjct: 1053 LNEGESLVSRILQL--GPPGTKFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFC 1110

Query: 95   D---------INLQSSYLN-PNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVT 144
            D         +N     L+ P  LE      K  C  +       F+VVS +K++S  + 
Sbjct: 1111 DYTEDELNEILNGMDEVLDSPEDLEK-----KRICRIITRDFPQYFAVVSRIKQDSNLIG 1165

Query: 145  KKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQSTSPL 204
             +G  L S++  ++   +P G  T  + V L+ QP+   LV  +   + TF      SP+
Sbjct: 1166 PEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATF------SPI 1219

Query: 205  IHIQHPSTYPFQKPVTLFLP 224
            + ++ P    F KP+T+ +P
Sbjct: 1220 VTLE-PRRRKFHKPITMTIP 1238


>gi|61742782 leucine rich repeat and death domain containing protein
           isoform 2 [Homo sapiens]
          Length = 753

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 122/568 (21%), Positives = 212/568 (37%), Gaps = 95/568 (16%)

Query: 46  VGDNEELVSNVITIECSDKEKRVPFP--IGIAIPFTARYRGNYRDIMVKVCDINLQS--- 100
           +G ++ L+S+V+ ++       V F   +G+ + FT       R+++V+  + N      
Sbjct: 224 LGPHDALLSHVLELQ----PHGVAFQQDVGLWLLFTPPQARRCREVVVRTRNDNSWGDLE 279

Query: 101 SYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKESFTVTKKGLALKSSMDSRISL 160
           +YL   + + +        A  +V     F VVS     +  V  +G  L SS    + +
Sbjct: 280 TYLEEEAPQRL-------WAHCQVPHFSWFLVVSRPVSNACLVPPEGTLLCSSGHPGVKV 332

Query: 161 NYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQSTSPLIHIQHPSTYPFQKPVT 220
            +PPG    P  V +++  +    +  L  + +      + SPL+ +       F +PVT
Sbjct: 333 IFPPGATEEPRRVSMQVVRMAGRELQALLGEPEA-----AVSPLLCLSQSGPPSFLQPVT 387

Query: 221 LFLPCSPYLDKNNLGSEIDHKRRASATINRITPSYFNRTKIASIRKPRKNASECLKLLGF 280
           + LP    L     G  +D  R                                L LL +
Sbjct: 388 VQLP----LPSGITGLSLDRSR--------------------------------LHLLYW 411

Query: 281 RSQDSGWCGLDDVVKTIQSGLVSVELYEHLERFIVLHLSSTMDNSHLVTFVKSLEEAMLS 340
               + W   DD+  T Q  L    LY          L  T  N       K+ E   L 
Sbjct: 412 APPAATW---DDI--TAQVVLELTHLY---------WLWYTTKNCVGGLARKAWERLRLH 457

Query: 341 TTACIVLSHQKDNPHRIAVLVVPSKDLSQVLKDLHLEGFGGPPEPSRHFQVREGEQLLLR 400
               I L  ++D P ++ +  +P   +   L+ L LE + GP EPS   ++ EGE+    
Sbjct: 458 RVNLIALQRRRD-PEQVLLQCLPRNKVDATLRRL-LERYRGP-EPSDTVEMFEGEEFFAA 514

Query: 401 FTGNIFASSNGKDYGKD-YTLIFHLQRKPRLELQIKEVDEFGNYSCPHYKGTIVVYKVPK 459
           F   I   ++  D  +     +F+   K   E+ +    +         +G +  Y+   
Sbjct: 515 FERGIDVDADRPDCVEGRICFVFYSHLKNVKEVYVTTTLD---REAQAVRGQVSFYRGAV 571

Query: 460 GKIVPNLNQSLVINENHSQLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEALWDNLLHW 519
              VP   ++    +    L +  LP+KLP+ +     P+    +S  P+     NL   
Sbjct: 572 PVRVPEEAEAARQRKGADALWMATLPIKLPRLRGS-EGPRRGAGLSLAPL-----NLGDA 625

Query: 520 LAEELSEENAESLSSTLPL-----------RRSTIQLIKLKNPDDLTEQIHEFLCFWKKS 568
               L++ N  S++  L L               +Q I+ +  DDL EQI   L  W + 
Sbjct: 626 ETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAER 685

Query: 569 LPTFTDKLRLLARHLRKIGRSDLAEELK 596
                  + LL + L +  R D+AEE++
Sbjct: 686 QAGQPGAVGLLVQALEQSDRQDVAEEVR 713


>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
          Length = 1897

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 16/148 (10%)

Query: 80   ARYRGNYRDIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKE 139
            +RY  +Y D ++   D  L        SLE ++   K  C  +       F ++S L ++
Sbjct: 1063 SRYGESYLDQILNGMDEEL-------GSLEELEK--KRVCRIITTDFPLYFVIMSRLCQD 1113

Query: 140  SFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQ 199
              T+  +G +LKS +   +   +P    T  V + L+ QPV   LV  L   Q TF    
Sbjct: 1114 YDTIGPEGGSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATF---- 1169

Query: 200  STSPLIHIQHPSTYPFQKPVTLFLPCSP 227
              SP++ ++ P    F +P+ L +P  P
Sbjct: 1170 --SPIVTVE-PRRRKFHRPIGLRIPLPP 1194


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 16/148 (10%)

Query: 80   ARYRGNYRDIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKE 139
            +RY  +Y D ++   D  L        SLE ++   K  C  +       F ++S L ++
Sbjct: 1022 SRYGESYLDQILNGMDEEL-------GSLEELEK--KRVCRIITTDFPLYFVIMSRLCQD 1072

Query: 140  SFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQ 199
              T+  +G +LKS +   +   +P    T  V + L+ QPV   LV  L   Q TF    
Sbjct: 1073 YDTIGPEGGSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATF---- 1128

Query: 200  STSPLIHIQHPSTYPFQKPVTLFLPCSP 227
              SP++ ++ P    F +P+ L +P  P
Sbjct: 1129 --SPIVTVE-PRRRKFHRPIGLRIPLPP 1153


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 16/148 (10%)

Query: 80   ARYRGNYRDIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKE 139
            +RY  +Y D ++   D  L        SLE ++   K  C  +       F ++S L ++
Sbjct: 1022 SRYGESYLDQILNGMDEEL-------GSLEELEK--KRVCRIITTDFPLYFVIMSRLCQD 1072

Query: 140  SFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQ 199
              T+  +G +LKS +   +   +P    T  V + L+ QPV   LV  L   Q TF    
Sbjct: 1073 YDTIGPEGGSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATF---- 1128

Query: 200  STSPLIHIQHPSTYPFQKPVTLFLPCSP 227
              SP++ ++ P    F +P+ L +P  P
Sbjct: 1129 --SPIVTVE-PRRRKFHRPIGLRIPLPP 1153


>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
          Length = 1719

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 16/148 (10%)

Query: 80   ARYRGNYRDIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKE 139
            +RY  +Y D ++   D  L        SLE ++   K  C  +       F ++S L ++
Sbjct: 1022 SRYGESYLDQILNGMDEEL-------GSLEELEK--KRVCRIITTDFPLYFVIMSRLCQD 1072

Query: 140  SFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQ 199
              T+  +G +LKS +   +   +P    T  V + L+ QPV   LV  L   Q TF    
Sbjct: 1073 YDTIGPEGGSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATF---- 1128

Query: 200  STSPLIHIQHPSTYPFQKPVTLFLPCSP 227
              SP++ ++ P    F +P+ L +P  P
Sbjct: 1129 --SPIVTVE-PRRRKFHRPIGLRIPLPP 1153


>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
          Length = 1856

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 40/148 (27%), Positives = 66/148 (44%), Gaps = 16/148 (10%)

Query: 80   ARYRGNYRDIMVKVCDINLQSSYLNPNSLEGMKGGYKGTCASVKVYKLGIFSVVSCLKKE 139
            +RY  +Y D ++   D  L        SLE ++   K  C  +       F ++S L ++
Sbjct: 1022 SRYGESYLDQILNGMDEEL-------GSLEELEK--KRVCRIITTDFPLYFVIMSRLCQD 1072

Query: 140  SFTVTKKGLALKSSMDSRISLNYPPGVFTSPVLVQLKIQPVDPALVAHLKAQQDTFYSVQ 199
              T+  +G +LKS +   +   +P    T  V + L+ QPV   LV  L   Q TF    
Sbjct: 1073 YDTIGPEGGSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATF---- 1128

Query: 200  STSPLIHIQHPSTYPFQKPVTLFLPCSP 227
              SP++ ++ P    F +P+ L +P  P
Sbjct: 1129 --SPIVTVE-PRRRKFHRPIGLRIPLPP 1153


>gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 7/86 (8%)

Query: 397 LLLRFTGNIFASSNGKDYGKDYTLIFHLQRKPRLELQIKEV---DEFGNYSCPHYKGT-- 451
           LLLRF  N F+ S     G D+ +        +++LQI +    + F   +  +Y+GT  
Sbjct: 24  LLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHG 83

Query: 452 -IVVYKVPKGKIVPNLNQSL-VINEN 475
            IVVY V   +   N+ + L  IN+N
Sbjct: 84  VIVVYDVTSAESFVNVKRWLHEINQN 109


>gi|31543630 solute carrier family 20 (phosphate transporter),
           member 1 [Homo sapiens]
          Length = 679

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 18/54 (33%), Positives = 28/54 (51%)

Query: 293 VVKTIQSGLVSVELYEHLERFIVLHLSSTMDNSHLVTFVKSLEEAMLSTTACIV 346
           V +TI+ GL+ VE+Y   +  ++    S M  S +   V S  +  +S T CIV
Sbjct: 81  VSETIRKGLIDVEMYNSTQGLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIV 134


>gi|158341646 hypothetical protein LOC729830 [Homo sapiens]
          Length = 1040

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 27/107 (25%), Positives = 41/107 (38%), Gaps = 24/107 (22%)

Query: 330 FVKSLEEAMLSTTACIVLSHQKDNPHRIAVLVVPSKDLSQV------------------- 370
           F++SL E    ++AC V    +  P +    + P KD SQ                    
Sbjct: 535 FLQSLTEEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVG 594

Query: 371 ----LKDLHLEGFGGPPEPSRHFQVREGEQLLLRFTGNIFASSNGKD 413
                 DL + G   P +P +H Q  +   LLL F G+    S+ +D
Sbjct: 595 SPGPYDDLEVSGPPAPIDPPKHIQEMKKNALLL-FKGSYIEESDFQD 640


>gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 851

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 478 QLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEA-LWDNLLHWLAEEL 524
           ++P+ K P+++PK K L   P     + K P++A LW +L    + EL
Sbjct: 765 EVPLWKSPVEVPKWKSLYGSPTVEVPLWKSPMKAPLWKSLYESFSMEL 812


>gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 1070

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 478  QLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEA-LWDNLLHWLAEEL 524
            ++P+ K P+++PK K L   P     + K P++A LW +L    + EL
Sbjct: 984  EVPLWKSPVEVPKWKSLYGSPTVEVPLWKSPMKAPLWKSLYESFSMEL 1031


>gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 1015

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 478 QLPICKLPLKLPKHKKLINRPQSTKRVSKDPVEA-LWDNLLHWLAEEL 524
           ++P+ K P+++PK K L   P     + K P++A LW +L    + EL
Sbjct: 929 EVPLWKSPVEVPKWKSLYGSPTVEVPLWKSPMKAPLWKSLYESFSMEL 976


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 14/122 (11%)

Query: 448 YKGTIVVYKVPKGKIVPNLNQSLVINENHSQLPICKLPL--KLPKHKKLINRPQSTKRVS 505
           Y   + V  + K  I  +L + L I E H+ + I  + +  K+P+  KL  R    K +S
Sbjct: 400 YTKNVEVLHLGKVWIPDDLRKRLNI-EMHAVVRITPVEVTPKIPRSLKLQPRENLPKDIS 458

Query: 506 KDPVEALWDNLLHWLAEELSEENAESLSSTLPLRRSTIQLIKLKNPDDLTEQIHEFLCFW 565
           ++ ++ ++ +   WL +        S ++ LPL  S  + IKL+  D L E     +  W
Sbjct: 459 EEDIKTVFYS---WLQQ--------STTTMLPLVISEEEFIKLETKDGLKEFSLSIVHSW 507

Query: 566 KK 567
           +K
Sbjct: 508 EK 509


>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
          Length = 740

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 16/102 (15%)

Query: 378 GFGGPPEPSRHFQVRE-GEQLLLRFT---------GNIFASSNGKDYGKDYTLIFHLQRK 427
           GFGG  + S + Q    GE+  +  T         G++  S NGKD G  + +  H++ +
Sbjct: 166 GFGGTGKKSHNKQFDNYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQ 225

Query: 428 ---PRLELQIKEVD-EFG--NYSCPHYKGTIVVYKVPKGKIV 463
              P   L+  E+   FG   +  P   G + + K P G IV
Sbjct: 226 ALFPACVLKNAELKFNFGEEEFKFPPKDGFVALSKAPDGYIV 267


>gi|13128864 histone deacetylase 6 [Homo sapiens]
          Length = 1215

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 14/49 (28%), Positives = 23/49 (46%)

Query: 554 LTEQIHEFLCFWKKSLPTFTDKLRLLARHLRKIGRSDLAEELKFKWENK 602
           L EQ++EF C W  S P   ++L  +   L + G  D     + ++  K
Sbjct: 90  LDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEK 138


>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 35/147 (23%), Positives = 55/147 (37%), Gaps = 15/147 (10%)

Query: 204 LIHIQHPSTYPFQKPVTLFLPCSPYLDKNNLGSEIDHKRRASATINRITPSYFNRTKIAS 263
           L+H+     Y FQ    L L  +      N G   DH R + +      P Y +R K+  
Sbjct: 839 LMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDR-KVHH 897

Query: 264 IRKPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSGLVSVELYEHLERFIVLHLSSTMD 323
           +   +K  +  + ++    QD              S +   E  E L   +V  L+S   
Sbjct: 898 MHMRKKGINTLINIMSRLGQDD----------PTPSRINHNERLEFLGDAVVEFLTSV-- 945

Query: 324 NSHLVTFVKSLEEAMLSTTACIVLSHQ 350
             HL     SLEE  L+T    ++ +Q
Sbjct: 946 --HLYYLFPSLEEGGLATYRTAIVQNQ 970


>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
          Length = 1374

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 35/147 (23%), Positives = 55/147 (37%), Gaps = 15/147 (10%)

Query: 204  LIHIQHPSTYPFQKPVTLFLPCSPYLDKNNLGSEIDHKRRASATINRITPSYFNRTKIAS 263
            L+H+     Y FQ    L L  +      N G   DH R + +      P Y +R K+  
Sbjct: 876  LMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDR-KVHH 934

Query: 264  IRKPRKNASECLKLLGFRSQDSGWCGLDDVVKTIQSGLVSVELYEHLERFIVLHLSSTMD 323
            +   +K  +  + ++    QD              S +   E  E L   +V  L+S   
Sbjct: 935  MHMRKKGINTLINIMSRLGQDD----------PTPSRINHNERLEFLGDAVVEFLTSV-- 982

Query: 324  NSHLVTFVKSLEEAMLSTTACIVLSHQ 350
              HL     SLEE  L+T    ++ +Q
Sbjct: 983  --HLYYLFPSLEEGGLATYRTAIVQNQ 1007


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,029,320
Number of Sequences: 37866
Number of extensions: 1083003
Number of successful extensions: 2435
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2386
Number of HSP's gapped (non-prelim): 49
length of query: 616
length of database: 18,247,518
effective HSP length: 108
effective length of query: 508
effective length of database: 14,157,990
effective search space: 7192258920
effective search space used: 7192258920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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