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Search of human proteins with 21735584
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21735584 oxysterol-binding protein-like protein 3 isoform d
[Homo sapiens]
(820 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [... 1674 0.0
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [... 1657 0.0
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [... 1655 0.0
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [... 1639 0.0
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [... 973 0.0
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [... 951 0.0
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] 782 0.0
gi|4505531 oxysterol binding protein [Homo sapiens] 310 3e-84
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 296 5e-80
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [... 293 3e-79
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa... 291 1e-78
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H... 289 8e-78
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 284 3e-76
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [... 106 8e-23
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ... 106 8e-23
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [... 106 8e-23
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap... 100 9e-21
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap... 99 1e-20
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap... 97 8e-20
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 92 3e-18
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 91 3e-18
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 91 3e-18
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap... 90 1e-17
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap... 90 1e-17
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap... 90 1e-17
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap... 90 1e-17
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] 75 2e-13
gi|217416392 pleckstrin homology domain containing, family H (wi... 57 5e-08
gi|55741447 pleckstrin homology domain containing, family H (wit... 45 2e-04
gi|46094081 development and differentiation enhancing factor 1 [... 44 5e-04
>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
[Homo sapiens]
Length = 820
Score = 1674 bits (4334), Expect = 0.0
Identities = 820/820 (100%), Positives = 820/820 (100%)
Query: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
Query: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
Query: 241 QSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSK 300
QSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSK
Sbjct: 241 QSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSK 300
Query: 301 MQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSSENSRD 360
MQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSSENSRD
Sbjct: 301 MQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSSENSRD 360
Query: 361 ENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNL 420
ENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNL
Sbjct: 361 ENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNL 420
Query: 421 SNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPV 480
SNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPV
Sbjct: 421 SNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPV 480
Query: 481 ELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNP 540
ELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNP
Sbjct: 481 ELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNP 540
Query: 541 VLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPI 600
VLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPI
Sbjct: 541 VLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPI 600
Query: 601 GTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKY 660
GTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKY
Sbjct: 601 GTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKY 660
Query: 661 WSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQ 720
WSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQ
Sbjct: 661 WSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQ 720
Query: 721 FALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENH 780
FALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENH
Sbjct: 721 FALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENH 780
Query: 781 VEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 820
VEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
Sbjct: 781 VEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 820
>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
[Homo sapiens]
Length = 851
Score = 1657 bits (4292), Expect = 0.0
Identities = 820/851 (96%), Positives = 820/851 (96%), Gaps = 31/851 (3%)
Query: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
Query: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
Query: 241 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR 269
QSMDVLHRTYSAPAINAIQ VPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
Query: 270 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 329
LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
Query: 330 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 389
LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE
Sbjct: 361 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 420
Query: 390 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 449
VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL
Sbjct: 421 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 480
Query: 450 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 509
PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP
Sbjct: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540
Query: 510 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 569
SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS
Sbjct: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600
Query: 570 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 629
ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG
Sbjct: 601 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 660
Query: 630 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 689
QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE
Sbjct: 661 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 720
Query: 690 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 749
SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF
Sbjct: 721 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 780
Query: 750 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 809
LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL
Sbjct: 781 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 840
Query: 810 GFSKLDHPVLW 820
GFSKLDHPVLW
Sbjct: 841 GFSKLDHPVLW 851
>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
[Homo sapiens]
Length = 856
Score = 1655 bits (4287), Expect = 0.0
Identities = 820/856 (95%), Positives = 820/856 (95%), Gaps = 36/856 (4%)
Query: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
Query: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
Query: 241 QSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSK 300
QSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSK
Sbjct: 241 QSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSETSSEFSK 300
Query: 301 MQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSS----- 355
MQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSS
Sbjct: 301 MQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSSALAQN 360
Query: 356 -------------------------------ENSRDENRALVHQLSNESRLSITDSLSEF 384
ENSRDENRALVHQLSNESRLSITDSLSEF
Sbjct: 361 TDLKERLRRIHAESLLLDSPAVAKSGDNLAEENSRDENRALVHQLSNESRLSITDSLSEF 420
Query: 385 FDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSR 444
FDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSR
Sbjct: 421 FDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSR 480
Query: 445 RRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDK 504
RRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDK
Sbjct: 481 RRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDK 540
Query: 505 AAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSH 564
AAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSH
Sbjct: 541 AAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSH 600
Query: 565 HPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIH 624
HPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIH
Sbjct: 601 HPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIH 660
Query: 625 NILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLF 684
NILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLF
Sbjct: 661 NILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLF 720
Query: 685 GKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFR 744
GKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFR
Sbjct: 721 GKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFR 780
Query: 745 PDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLE 804
PDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLE
Sbjct: 781 PDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLE 840
Query: 805 LRKDLGFSKLDHPVLW 820
LRKDLGFSKLDHPVLW
Sbjct: 841 LRKDLGFSKLDHPVLW 856
>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
[Homo sapiens]
Length = 887
Score = 1639 bits (4245), Expect = 0.0
Identities = 820/887 (92%), Positives = 820/887 (92%), Gaps = 67/887 (7%)
Query: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
Query: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
Query: 241 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR 269
QSMDVLHRTYSAPAINAIQ VPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
Query: 270 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 329
LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
Query: 330 LKQLMEQDASSSPSAQVIGLKNALSS---------------------------------- 355
LKQLMEQDASSSPSAQVIGLKNALSS
Sbjct: 361 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 420
Query: 356 --ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 413
ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
Sbjct: 421 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 480
Query: 414 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 473
NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
Sbjct: 481 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 540
Query: 474 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 533
SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
Sbjct: 541 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 600
Query: 534 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 593
GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
Sbjct: 601 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 660
Query: 594 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 653
SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
Sbjct: 661 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 720
Query: 654 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 713
NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
Sbjct: 721 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 780
Query: 714 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 773
QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
Sbjct: 781 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 840
Query: 774 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 820
RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
Sbjct: 841 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 887
>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
[Homo sapiens]
Length = 934
Score = 973 bits (2515), Expect = 0.0
Identities = 504/935 (53%), Positives = 644/935 (68%), Gaps = 116/935 (12%)
Query: 1 MMSDEKNLGVSQKLVSPSR--STSSCSSKQGSRQ-------------------------- 32
M SDEK + + K +P+ ++SS SS++ SRQ
Sbjct: 1 MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60
Query: 33 -------DSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAK 85
DSWE++EGL+ Q+P +GF+LKKRKWPLKGWHKRFF LD G+LKY+K
Sbjct: 61 VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120
Query: 86 SQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145
+ DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVKS++ FD WVSKLRHHR
Sbjct: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180
Query: 146 MYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SSISKQNLFQTGSNVSFS 202
+YRQNEI P + + H F ++ +SS S+ K +S Q+ +++ +
Sbjct: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240
Query: 203 CG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAIN----- 256
C G+++V WLQ SE+M++C++DLAHC + LVE+S+LLQ++++L RT SAP
Sbjct: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300
Query: 257 ------------------------AIQVPKPFSG---PVRLHSSNPNL-STLDFGEEKNY 288
IQ+ PFS PVRLHSSNPNL + ++F ++
Sbjct: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360
Query: 289 -SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQV 346
+D E+S++++K+QE+ C IA KV+ L+SAFN ++ E+EKLKQ++ EQD S S Q+
Sbjct: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420
Query: 347 IGLKNALS-----------------SEN-------------SRDENRALVH-------QL 369
L+ +LS SE+ S DE +H Q+
Sbjct: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQV 480
Query: 370 SNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQ 429
+NESRLS+++S+SEFFDAQEVLLS SSSENE SDD+SY+SD+SDN+S DN S + RQ
Sbjct: 481 ANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQ 540
Query: 430 TLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTL 489
L L G ++ RR CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTL
Sbjct: 541 ILNGELTGGA-FRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTL 599
Query: 490 QRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECI 549
Q LCEE+EYSELLDKA++ P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECI
Sbjct: 600 QHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI 659
Query: 550 REDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 609
REDKGF+FFSEQVSHHPPISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP
Sbjct: 660 REDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 719
Query: 610 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 669
+GD++ WNKVT+CIHNILSG+RWIEHYGE+ I+N C CK+ F+K YW++N +E++
Sbjct: 720 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 779
Query: 670 GTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMD 729
G V D+ GKAV+RLFGKWHE +YCG S+ C+WR MP YE YY FT+FA+ELNE+D
Sbjct: 780 GVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELD 839
Query: 730 PSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 789
P K LLPPTD RFRPDQRFLEEGNLE A +KQR+E+LQR RRR +EEN++EH P+FF+
Sbjct: 840 PVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFK 899
Query: 790 KSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW 820
K D ++WVSN TY ELRKD GFSK+D PVLW
Sbjct: 900 KVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934
>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
[Homo sapiens]
Length = 938
Score = 951 bits (2457), Expect = 0.0
Identities = 493/916 (53%), Positives = 629/916 (68%), Gaps = 112/916 (12%)
Query: 10 VSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGW 69
VS++L+ P S DSWE++EGL+ Q+P +GF+LKKRKWPLKGW
Sbjct: 30 VSRQLLEPEPVPLS------KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGW 83
Query: 70 HKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVK 129
HKRFF LD G+LKY+K+ DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVK
Sbjct: 84 HKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVK 143
Query: 130 SEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SS 186
S++ FD WVSKLRHHR+YRQNEI P + + H F ++ +SS S+ K +S
Sbjct: 144 SQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNS 203
Query: 187 ISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDV 245
Q+ +++ +C G+++V WLQ SE+M++C++DLAHC + LVE+S+LLQ++++
Sbjct: 204 FPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEI 263
Query: 246 LH-----------------------------RTYSAPAINAIQVPK-------------- 262
L RT S IQ+ +
Sbjct: 264 LQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRR 323
Query: 263 -----------PFSG---PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLC 306
PFS PVRLHSSNPNL + ++F ++ +D E+S++++K+QE+ C
Sbjct: 324 QRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFC 383
Query: 307 HIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALS----------- 354
IA KV+ L+SAFN ++ E+EKLKQ++ EQD S S Q+ L+ +LS
Sbjct: 384 LIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRS 443
Query: 355 ------SEN-------------SRDENRALVH-------QLSNESRLSITDSLSEFFDAQ 388
SE+ S DE +H Q++NESRLS+++S+SEFFDAQ
Sbjct: 444 RLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQ 503
Query: 389 EVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTC 448
EVLLS SSSENE SDD+SY+SD+SDN+S DN S + RQ L L G ++ RR C
Sbjct: 504 EVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGA-FRNGRRAC 562
Query: 449 LPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQI 508
LPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTLQ LCEE+EYSELLDKA++
Sbjct: 563 LPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASET 622
Query: 509 PSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPI 568
P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECIREDKGF+FFSEQVSHHPPI
Sbjct: 623 DDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPI 682
Query: 569 SACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILS 628
SACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP +GD++ WNKVT+CIHNILS
Sbjct: 683 SACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILS 742
Query: 629 GQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWH 688
G+RWIEHYGE+ I+N C CK+ F+K YW++N +E++G V D+ GKAV+RLFGKWH
Sbjct: 743 GRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWH 802
Query: 689 ESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQR 748
E +YCG S+ C+WR MP YE YY FT+FA+ELNE+DP K LLPPTD RFRPDQR
Sbjct: 803 EGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQR 862
Query: 749 FLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTYLE 804
FLEEGNLE A +KQR+E+LQR RRR +EEN++EH P+FF+K D ++WVSN TY E
Sbjct: 863 FLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWE 922
Query: 805 LRKDLGFSKLDHPVLW 820
LRKD GFSK+D PVLW
Sbjct: 923 LRKDPGFSKVDSPVLW 938
>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
Length = 842
Score = 782 bits (2020), Expect = 0.0
Identities = 421/862 (48%), Positives = 538/862 (62%), Gaps = 89/862 (10%)
Query: 17 PSRSTSSCSSKQGSRQDSWEVVE------GLRGEMNYTQEPPVQKGFLLKKRKWPLKGWH 70
P + SS S + WEVVE G G M P Q+G LLKKRKWPLKGWH
Sbjct: 12 PESAQSSKPSSAQQASELWEVVEEPRVRLGTEGVM-----PERQEGHLLKKRKWPLKGWH 66
Query: 71 KRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS 130
KR+F L+ GIL YA ++ DI + KLHG IDV LSVMS+ K ++ IDLDTE++IYHLK+KS
Sbjct: 67 KRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS 126
Query: 131 EEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQ 190
+++F WV++LR HR+ + D G S + RK
Sbjct: 127 QDLFQSWVAQLRAHRLAHR-------------------LDMPRGSLPSTAHRKVPGAQ-- 165
Query: 191 NLFQTGSNVSF--SCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHR 248
T + S G +V WL+ S+ +++CS +L+ C L E+ +LLQS++ LHR
Sbjct: 166 --LPTAATASALPGLGPREKVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQSLESLHR 223
Query: 249 TYSAPAINAIQVPKPFSGPV------------------------RLHSSNPNLSTLDFGE 284
SAP I Q P RLH S PNLS
Sbjct: 224 IPSAPVIPTHQASVTTERPKKGKRTSRMWCTQSFAKDDTIGRVGRLHGSVPNLSRYLESR 283
Query: 285 EKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLK------------- 331
+ + + G + +++ +Q +A KV+ +L S ++ ER++L+
Sbjct: 284 DSSGTRGLPPT-DYAHLQRSFWALAQKVHSSLSSVLAALTMERDQLRDMHQGSELSRMGV 342
Query: 332 --------QLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSE 383
+L SS +A N E + R L QLS S LS+ DS +E
Sbjct: 343 SEASTGQRRLHSLSTSSDTTADSFSSLNPEEQEALYMKGRELTPQLSQTSILSLADSHTE 402
Query: 384 FFDAQEVLLSPSSSENEISDDD-SYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 442
FFDA EVLLS SSSENE S+++ S S+I+ +LS + L DL + GR
Sbjct: 403 FFDACEVLLSASSSENEGSEEEESCTSEITTSLSEEML--DLRGAERCQKGGCVPGRPMG 460
Query: 443 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 502
RR CLPA +++SLWNILRNNIGKDLSKV+MPV+LNEPLNTLQRLCEELEYS LL
Sbjct: 461 PPRRRCLPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLL 520
Query: 503 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 562
D+A++I P ERMVY+AAFA+SAY+S+Y+RAG KPFNPVLGETYEC R D+GF+F SEQV
Sbjct: 521 DQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQV 580
Query: 563 SHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSC 622
SHHPPISACHAES NF FWQD++WKNKFWGKS+EIVP+GT +V+LP FGDHFEWNKVTSC
Sbjct: 581 SHHPPISACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSC 640
Query: 623 IHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHR 682
IHN+LSGQRWIEHYGE++I+N D SC+CK+ F KAKYWS+N HE++G V RSG+ +HR
Sbjct: 641 IHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVLHR 700
Query: 683 LFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTR 742
LFGKWHE +Y G C+W+ N MP +E+ + FTQFALELNE+ K LP TDTR
Sbjct: 701 LFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTR 760
Query: 743 FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDS----WVS 798
RPDQR+LEEGN++ AE QK+RIEQLQR+RR+V+EEN++ HQ RFFR+ D S WV+
Sbjct: 761 LRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDSSGKEWWVT 820
Query: 799 NGTYLELRKDLGFSKLDHPVLW 820
N TY LR + G+ +D VLW
Sbjct: 821 NNTYWRLRAEPGYGNMDGAVLW 842
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 310 bits (794), Expect = 3e-84
Identities = 225/747 (30%), Positives = 363/747 (48%), Gaps = 109/747 (14%)
Query: 54 QKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSK 113
++G+L K + +KG+ +R+F L G+L Y +S+ ++ R G I++ + ++V+ S
Sbjct: 91 REGWLFKWTNY-IKGYQRRWFVLSNGLLSYYRSKAEM-RHTCRGTINLATANITVEDSCN 148
Query: 114 CIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSS 173
I + YHLK SE WV+ L + + + M S
Sbjct: 149 FIISNGGAQTYHLKASSEVERQRWVTALE---LAKAKAVKMLAES------------DES 193
Query: 174 GVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYL 233
G +S+S ++ + QN +T S+ +DL+ C+ +
Sbjct: 194 GDEESVSQTDKTEL--QNTLRTLSSKV-----------------------EDLSTCNDLI 228
Query: 234 VEMSQLLQSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSE 293
+ LQ S + ++++P + ++ + L +
Sbjct: 229 AKHGTALQR--------SLSELESLKLPAESNEKIKQVNERATLFRI------------- 267
Query: 294 TSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQ-VIGLKNA 352
TS+ D +A + + +R +L++ +EQ A +
Sbjct: 268 TSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATV 327
Query: 353 LSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDIS 412
L + + S + +S D +EFFDA E++ P + ++ + S +S S
Sbjct: 328 LPANTPGNVGSGKDQCCSGKGDMSDEDDENEFFDAPEIITMPENLGHKRTG--SNISGAS 385
Query: 413 DNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKD 472
++SLD + + L E K +RT +P + +++LW+I++N IGK+
Sbjct: 386 SDISLD------EQYKHQL-------EETKKEKRTRIPYK--PNYSLNLWSIMKNCIGKE 430
Query: 473 LSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYR 532
LSK+ MPV NEPL+ LQRL E+LEY ELLD+AA+ + LE++ YVAAF +S+Y+++ +R
Sbjct: 431 LSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFR 490
Query: 533 AGSKPFNPVLGETYECIR-EDKGFQFFSEQVSHHPPISACHAESRN-FVFWQDVRWKNKF 590
SKPFNP+LGET+E R E+ G++ EQVSHHPP +A HAES+N + Q+++ +KF
Sbjct: 491 T-SKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKF 549
Query: 591 WGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCY 650
GK + I+P+GT H G H+ W KVT+ +HNI+ G+ WI+ GEI I N H
Sbjct: 550 RGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVN-HKTGDK 608
Query: 651 CKVNFIKAKYWSTN-AHEIEGTVFDRSGKAVHRLFGKWHESIYC---------GGG---- 696
C + F+ Y+S + A ++ G V D SGK L G W E + C GG
Sbjct: 609 CNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQ 668
Query: 697 ------SSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFL 750
S +W+ NP+PK E Y F++ AL LN + + PTD+R RPDQR +
Sbjct: 669 RGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLNAWESGT----APTDSRLRPDQRLM 724
Query: 751 EEGNLEEAEIQKQRIEQLQRERRRVLE 777
E G +EA +KQR+E+ QR R+ E
Sbjct: 725 ENGRWDEANAEKQRLEEKQRLSRKKRE 751
>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
sapiens]
Length = 950
Score = 296 bits (758), Expect = 5e-80
Identities = 182/523 (34%), Positives = 271/523 (51%), Gaps = 79/523 (15%)
Query: 348 GLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSY 407
G++N E +++N+ L L + +E + ++ L+ S + +S+D+ Y
Sbjct: 427 GVRN-FKLEQEQEKNKILSEALETLA--------TEHHELEQSLVKGSPPASILSEDEFY 477
Query: 408 --VSDISDNLSLDNL----SNDLDNERQTLGPVLDSGREAKS------------RRRTCL 449
+SD SL L + + E + LG E K + RT L
Sbjct: 478 DALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSL 537
Query: 450 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 509
P+P S ++ S+W+ILR IG +LSK+ MPV NEPL+ LQRL E +E++ L+ KA+ +
Sbjct: 538 PSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLS 597
Query: 510 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 569
P+ERM VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+ SEQVSHHPPIS
Sbjct: 598 DPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVSHHPPIS 656
Query: 570 ACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNIL 627
A HAE N F+F + K KFWGKS+E P GT + L + + W T C+HNI+
Sbjct: 657 AFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNII 716
Query: 628 SGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKW 687
G+ WIE YG + I N H C +NF + H++EG + D+S K + L+GKW
Sbjct: 717 VGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKW 775
Query: 688 HESIYCGGGSS-------------------------------------------SACVWR 704
E +Y ++ S +WR
Sbjct: 776 TECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWR 835
Query: 705 ANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQR 764
P P Q Y+FT FA+ LNE+D +S++P TD R RPD R +E G +++A +K+R
Sbjct: 836 IAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKR 895
Query: 765 IEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 802
+E+ QR R+ ++ + + R+F + + W+ +G+Y
Sbjct: 896 LEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 938
>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
[Homo sapiens]
Length = 480
Score = 293 bits (751), Expect = 3e-79
Identities = 180/475 (37%), Positives = 251/475 (52%), Gaps = 63/475 (13%)
Query: 383 EFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 442
EFFDA S +SS E S+ + V+ + D + N ER P ++G +
Sbjct: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGER----PSQENGIQ-- 58
Query: 443 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 502
+ RT LPAP S S+ S+W IL+ +G +LSK+ MP+ NEPL+ LQR+ E +E+ L+
Sbjct: 59 -KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117
Query: 503 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 562
+A+ P PLERM VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQV
Sbjct: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176
Query: 563 SHHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVT 620
SHHPPISA H+E N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236
Query: 621 SCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAV 680
C+HN++ G+ WIE YG + I N H C ++F + H++EG + D++ K +
Sbjct: 237 CCVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295
Query: 681 HRLFGKWHESIY----------------------------CGGGSS-------------- 698
++GKW E ++ G S
Sbjct: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355
Query: 699 ----SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGN 754
S +WR N P Q Y+FT F + LNE++ + LPPTD R RPD R +E GN
Sbjct: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415
Query: 755 LEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 804
++ A +K+R+E+ QRE RR + E Q R+F ++ W+ G Y E
Sbjct: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 470
>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
sapiens]
Length = 437
Score = 291 bits (746), Expect = 1e-78
Identities = 160/409 (39%), Positives = 229/409 (55%), Gaps = 52/409 (12%)
Query: 444 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 503
+ RT LP+P S ++ S+W+ILR IG +LSK+ MPV NEPL+ LQRL E +E++ L+
Sbjct: 19 KHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIH 78
Query: 504 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 563
KA+ + P+ERM VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+ SEQVS
Sbjct: 79 KASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVS 137
Query: 564 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 621
HHPPISA HAE N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 138 HHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTC 197
Query: 622 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 681
C+HNI+ G+ WIE YG + I N H C +NF + H++EG + D+S K +
Sbjct: 198 CVHNIIVGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLC 256
Query: 682 RLFGKWHESIYCGGGSS------------------------------------------- 698
L+GKW E +Y ++
Sbjct: 257 ALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPG 316
Query: 699 SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEA 758
S +WR P P Q Y+FT FA+ LNE+D +S++P TD R RPD R +E G +++A
Sbjct: 317 SVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQA 376
Query: 759 EIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 802
+K+R+E+ QR R+ ++ + + R+F + + W+ +G+Y
Sbjct: 377 SEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425
>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
sapiens]
Length = 468
Score = 289 bits (739), Expect = 8e-78
Identities = 163/414 (39%), Positives = 225/414 (54%), Gaps = 55/414 (13%)
Query: 444 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 503
+ RT LPAP S S+ S+W IL+ +G +LSK+ MP+ NEPL+ LQR+ E +E+ L+
Sbjct: 47 KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 106
Query: 504 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 563
+A+ P PLERM VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQVS
Sbjct: 107 RASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVS 165
Query: 564 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 621
HHPPISA H+E N F+F + K KFWGKS+E P GT + L + + W T
Sbjct: 166 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 225
Query: 622 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 681
C+HN++ G+ WIE YG + I N H C ++F + H++EG + D++ K +
Sbjct: 226 CVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF 284
Query: 682 RLFGKWHESIY----------------------------CGGGSS--------------- 698
++GKW E ++ G S
Sbjct: 285 MIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQV 344
Query: 699 ---SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNL 755
S +WR N P Q Y+FT F + LNE++ + LPPTD R RPD R +E GN+
Sbjct: 345 IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNM 404
Query: 756 EEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 804
+ A +K+R+E+ QRE RR + E Q R+F ++ W+ G Y E
Sbjct: 405 DLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 458
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 284 bits (726), Expect = 3e-76
Identities = 224/753 (29%), Positives = 355/753 (47%), Gaps = 111/753 (14%)
Query: 55 KGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCID-VGLSVMSVKKSSK 113
+G+LLK + LKG+ +R+F L G+L Y ++Q E H C + LS +
Sbjct: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQG----EMAHTCRGTINLSTAHIDTEDS 240
Query: 114 C-IDLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSS 172
C I L + YHLK SE +W++ L + + + + +T +D S
Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITALE---LAKAKAVRVM----------NTHSDDS 287
Query: 173 SGVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAY 232
+ K L T N+S DL+ C+
Sbjct: 288 GD-----DDEATTPADKSELHHTLKNLSLKLD--------------------DLSTCNDL 322
Query: 233 LVEMSQLLQSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGS 292
+ + LQ S ++ +++P +++ + L +
Sbjct: 323 IAKHGAALQR--------SLTELDGLKIPSESGEKLKVVNERATLFRI------------ 362
Query: 293 ETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNA 352
TS+ D +A + A +R L++ +EQ A S L+ A
Sbjct: 363 -TSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNS-----LERA 416
Query: 353 LSSENSRDEN--RALVHQ--LSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYV 408
S R N ++ + L+ + S D +E+FDA E S + E +D
Sbjct: 417 FHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKA 476
Query: 409 SDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNN 468
+ S+D S D + +L P S K +RR +P + +++LW+I++N
Sbjct: 477 EGSTGTSSVDWSSADNVLDGASLVPKGSS----KVKRRVRIPNK--PNYSLNLWSIMKNC 530
Query: 469 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 528
IG++LS++ MPV NEPL+ LQRL E+LEY LLDKA S +E+M VAAF++S+Y++
Sbjct: 531 IGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYST 590
Query: 529 SYYRAGSKPFNPVLGETYECIR-EDKGFQFFSEQVSHHPPISACHAESRN-FVFWQDVRW 586
+ +R +KPFNP+LGET+E R +D G + EQVSHHPP +A + S++ + WQ++
Sbjct: 591 TVHRI-AKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITI 649
Query: 587 KNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHD 646
+KF GK + I+P+G H+ G+H+ W K TS +HNI+ G+ WI+ G+I I N H
Sbjct: 650 SSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVN-HK 708
Query: 647 DSCYCKVNFIKAKYWSTN-AHEIEGTVFDRSGKAVHRLFGKWHESIYCG----------- 694
+ C++ F+ Y+S A ++ G V D GKA + L G W E + C
Sbjct: 709 TNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPS 768
Query: 695 ---------GGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRP 745
S+ +W+ P+P+ E Y F++ AL LNE + + PTD+R RP
Sbjct: 769 SDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEG----VAPTDSRLRP 824
Query: 746 DQRFLEEGNLEEAEIQKQRIEQLQR-ERRRVLE 777
DQR +E+G +EA +KQR+E+ QR RRR LE
Sbjct: 825 DQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLE 857
>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
[Homo sapiens]
Length = 879
Score = 106 bits (265), Expect = 8e-23
Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)
Query: 455 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 512
S N SL W +L+ G DLS+V +P + EP + L +L + +++LL +AA
Sbjct: 364 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 423
Query: 513 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 565
RM V + Y S +Y+ KP+NP+LGET+ C + D + +EQVSHH
Sbjct: 424 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 479
Query: 566 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 623
PP+SA H +R F + K++F+G S+ + G +T + + +
Sbjct: 480 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 539
Query: 624 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 680
IL G +E G++ I+ ++ ++ F ++ ST+ ++I G + SG+ V
Sbjct: 540 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 596
Query: 681 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 738
L G W ++ G SSA W P G + Q + L E L
Sbjct: 597 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 650
Query: 739 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 788
++ R + +G+ A +K +E+ QR+R R +E+ + +P+ F
Sbjct: 651 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 696
>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 106 bits (265), Expect = 8e-23
Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)
Query: 455 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 512
S N SL W +L+ G DLS+V +P + EP + L +L + +++LL +AA
Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355
Query: 513 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 565
RM V + Y S +Y+ KP+NP+LGET+ C + D + +EQVSHH
Sbjct: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411
Query: 566 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 623
PP+SA H +R F + K++F+G S+ + G +T + + +
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
Query: 624 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 680
IL G +E G++ I+ ++ ++ F ++ ST+ ++I G + SG+ V
Sbjct: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528
Query: 681 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 738
L G W ++ G SSA W P G + Q + L E L
Sbjct: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582
Query: 739 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 788
++ R + +G+ A +K +E+ QR+R R +E+ + +P+ F
Sbjct: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
[Homo sapiens]
Length = 811
Score = 106 bits (265), Expect = 8e-23
Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)
Query: 455 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 512
S N SL W +L+ G DLS+V +P + EP + L +L + +++LL +AA
Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355
Query: 513 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 565
RM V + Y S +Y+ KP+NP+LGET+ C + D + +EQVSHH
Sbjct: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411
Query: 566 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 623
PP+SA H +R F + K++F+G S+ + G +T + + +
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471
Query: 624 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 680
IL G +E G++ I+ ++ ++ F ++ ST+ ++I G + SG+ V
Sbjct: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528
Query: 681 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 738
L G W ++ G SSA W P G + Q + L E L
Sbjct: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582
Query: 739 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 788
++ R + +G+ A +K +E+ QR+R R +E+ + +P+ F
Sbjct: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628
>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
sapiens]
Length = 736
Score = 99.8 bits (247), Expect = 9e-21
Identities = 181/808 (22%), Positives = 306/808 (37%), Gaps = 140/808 (17%)
Query: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSSKCIDL 117
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLRH----HRMYRQNEIAMFPHEVNHFFSGSTITDSSS 173
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADAYL 130
Query: 174 GVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKC------SKDLA 227
+ I K QN + ET + E ++ C +KD +
Sbjct: 131 QIL--IEQLKLFDDKLQNCKEDEQRKKIETLKETTNSM----VESIKHCIVLLQIAKDQS 184
Query: 228 HCHAYLVEMSQLLQSMDVLHRTYSA-PAINAI--QVPKPFSGPVRLHSSNPNLSTLDFGE 284
+ + M + +D +++ P I+ + Q P PV+L S S+L G
Sbjct: 185 NAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLP-PEPVQLCKSEQRPSSLPVGP 243
Query: 285 ------EKNYSDGSETSSEFSKMQEDLCHIAH-KVYFTLRSAFNIMSAEREKLKQLMEQD 337
+ T S S L +H + F+ S+E E
Sbjct: 244 VLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQ 303
Query: 338 ASSSPSAQVIGLKNALSSENSRDENRALVHQLSNES--RLSITDSLSEFFDAQEVLLSPS 395
+ SSP K + S S L H S S R T+SL+ S
Sbjct: 304 SGSSP-------KRLIDSSGSAS---VLTHSSSGNSLKRPDTTESLN------------S 341
Query: 396 SSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPS 455
S N SD D + D D+ D + ++ + + +L R
Sbjct: 342 SLSNGTSDADLF--DSHDDRDDDAEAGSVEEHKSVIMHLLSQVR---------------- 383
Query: 456 SSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERM 515
+G DL+KV +P + E + L+ + + +L + P +RM
Sbjct: 384 -------------LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRM 430
Query: 516 VYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC--------------IRED------ 552
V V + +SA+ + R GS KP+NP+LGE ++C + E
Sbjct: 431 VQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVS 488
Query: 553 -KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 609
F +EQVSHHPPISA +AE ++ F + K+KF G S+ + IG V+
Sbjct: 489 KNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLD 548
Query: 610 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 669
+ +H+ +IL+ W+E GE I N + F ++ H I
Sbjct: 549 YDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRIT 606
Query: 670 GTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW---RANPMPKGYEQYYSFTQFALEL 725
+F K+ + G+W+ +Y + V+ + P+ K + +
Sbjct: 607 AEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE------DQ 660
Query: 726 NEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQP 785
NE + S+SL D F L+ +++ A K R+E+ QR R +E ++ +
Sbjct: 661 NEYE--SRSLW--KDVTFN-----LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWET 711
Query: 786 RFFRKSDDDSWVSNGTYLELRKDLGFSK 813
R F + D + WV + L K LG +K
Sbjct: 712 RLFHE-DGECWVYDEPLL---KRLGAAK 735
>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
sapiens]
Length = 723
Score = 99.4 bits (246), Expect = 1e-20
Identities = 178/802 (22%), Positives = 301/802 (37%), Gaps = 141/802 (17%)
Query: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSSKCIDL 117
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLRH----HRMYRQNEIAMFPHEVNHFFSGSTITDSSS 173
++ +H + + + ++W+ L H + Q + F V F T D+
Sbjct: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADAYL 130
Query: 174 GVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYL 233
+ I + LF +C + + E + + HC L
Sbjct: 131 QIL----------IEQLKLFDDKLQ---NCKEDEQRKKIETLKETTNSMVESIKHCIVLL 177
Query: 234 VEMSQLLQSMDVLHRTYSA-PAINAI--QVPKPFSGPVRLHSSNPNLSTLDFGE------ 284
+ +D +++ P I+ + Q P PV+L S S+L G
Sbjct: 178 QIAKSTINPVDAIYQPSPLEPVISTMPSQTVLP-PEPVQLCKSEQRPSSLPVGPVLATLG 236
Query: 285 EKNYSDGSETSSEFSKMQEDLCHIAH-KVYFTLRSAFNIMSAEREKLKQLMEQDASSSPS 343
+ T S S L +H + F+ S+E E + SSP
Sbjct: 237 HHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSP- 295
Query: 344 AQVIGLKNALSSENSRDENRALVHQLSNES--RLSITDSLSEFFDAQEVLLSPSSSENEI 401
K + S S L H S S R T+SL+ SS N
Sbjct: 296 ------KRLIDSSGSAS---VLTHSSSGNSLKRPDTTESLN------------SSLSNGT 334
Query: 402 SDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISL 461
SD D + D D+ D + ++ + + +L R
Sbjct: 335 SDADLF--DSHDDRDDDAEAGSVEEHKSVIMHLLSQVR---------------------- 370
Query: 462 WNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAF 521
+G DL+KV +P + E + L+ + + +L + P +RMV V +
Sbjct: 371 -------LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKW 423
Query: 522 AISAYASSYYRAGS---KPFNPVLGETYEC--------------IRED-------KGFQF 557
+SA+ + R GS KP+NP+LGE ++C + E F
Sbjct: 424 YLSAFHAG--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTF 481
Query: 558 FSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFE 615
+EQVSHHPPISA +AE ++ F + K+KF G S+ + IG V+ + +H+
Sbjct: 482 VAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYI 541
Query: 616 WNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFD- 674
+IL+ W+E GE I N + F ++ H I +F
Sbjct: 542 LTFPNGYGRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYGGKKHRITAEIFSP 599
Query: 675 RSGKAVHRLFGKWHESIYCGGGSSSACVW---RANPMPKGYEQYYSFTQFALELNEMDPS 731
K+ + G+W+ +Y + V+ + P+ K + + NE +
Sbjct: 600 NDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE------DQNEYE-- 651
Query: 732 SKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKS 791
S+SL D F L+ +++ A K R+E+ QR R +E ++ + R F +
Sbjct: 652 SRSLW--KDVTFN-----LKIRDIDAATEAKHRLEERQRAEARERKEKEIQWETRLFHE- 703
Query: 792 DDDSWVSNGTYLELRKDLGFSK 813
D + WV + L K LG +K
Sbjct: 704 DGECWVYDEPLL---KRLGAAK 722
>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
sapiens]
Length = 746
Score = 96.7 bits (239), Expect = 8e-20
Identities = 180/815 (22%), Positives = 306/815 (37%), Gaps = 144/815 (17%)
Query: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + +
Sbjct: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70
Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQ--NEIAMFPHE-VNHFFSGSTITD 170
++ +H + + + ++W+ L H + Q +A F ++ S I
Sbjct: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISPVLEFSKIIG 130
Query: 171 SSSGVFDSISSRKRS----------SISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDME 220
SG S+ + I + LF +C + + E
Sbjct: 131 LDSGFVPSVQDFDKKLTEADAYLQILIEQLKLFDDKLQ---NCKEDEQRKKIETLKETTN 187
Query: 221 KCSKDLAHCHAYLVEMSQLLQSMDVLHR-TYSAPAINAI--QVPKPFSGPVRLHSSNPNL 277
+ + HC L + +D +++ + P I+ + Q P PV+L S
Sbjct: 188 SMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLP-PEPVQLCKSEQRP 246
Query: 278 STLDFGE------EKNYSDGSETSSEFSKMQEDLCHIAH-KVYFTLRSAFNIMSAEREKL 330
S+L G + T S S L +H + F+ S+E E
Sbjct: 247 SSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFY 306
Query: 331 KQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNES--RLSITDSLSEFFDAQ 388
+ SSP K + S S L H S S R T+SL+
Sbjct: 307 DADEFHQSGSSP-------KRLIDSSGSAS---VLTHSSSGNSLKRPDTTESLN------ 350
Query: 389 EVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTC 448
SS N SD D + D D+ D + ++ + + +L R
Sbjct: 351 ------SSLSNGTSDADLF--DSHDDRDDDAEAGSVEEHKSVIMHLLSQVR--------- 393
Query: 449 LPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQI 508
+G DL+KV +P + E + L+ + + +L +
Sbjct: 394 --------------------LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQ 433
Query: 509 PSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC--------------IRE 551
P +RMV V + +SA+ + R GS KP+NP+LGE ++C + E
Sbjct: 434 KDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSE 491
Query: 552 -------DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGT 602
F +EQVSHHPPISA +AE ++ F + K+KF G S+ + IG
Sbjct: 492 GPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQ 551
Query: 603 THVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWS 662
V+ + +H+ +IL+ W+E GE I N + F ++
Sbjct: 552 GCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCSKTGYSANIIFHTKPFYG 609
Query: 663 TNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW---RANPMPKGYEQYYSF 718
H I +F K+ + G+W+ +Y + V+ + P+ K +
Sbjct: 610 GKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFVDTKKLPIIKKKVRKLE- 668
Query: 719 TQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEE 778
+ NE + S+SL D F L+ +++ A K R+E+ QR R +E
Sbjct: 669 -----DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEAKHRLEERQRAEARERKE 714
Query: 779 NHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 813
++ + R F + D + WV + L K LG +K
Sbjct: 715 KEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 745
>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
sapiens]
Length = 764
Score = 91.7 bits (226), Expect = 3e-18
Identities = 122/587 (20%), Positives = 231/587 (39%), Gaps = 91/587 (15%)
Query: 250 YSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGSET---SSEFSKMQEDLC 306
+ +PA A + +SG +LH ++ ++ G++KN E+ S + + +DL
Sbjct: 221 HKSPAA-ARRAKSQYSG--QLHEVREMMNQVE-GQQKNLVHAIESLPGSGPLTALDQDLL 276
Query: 307 HIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALV 366
+ TL ++ ++ + Q + S ++G + S + +N L
Sbjct: 277 LLKATSAATLSCLGECLNLLQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLG 336
Query: 367 HQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSL--DNLSNDL 424
S + ++ + P+S+E+E + + L L D S++
Sbjct: 337 SLPSASANITWA-------------ILPNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNE 383
Query: 425 DNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNE 484
D E LG + D +I L I + +G DL+KV +P + E
Sbjct: 384 DKEETELGVMEDQ-------------------RSIILHLISQLKLGMDLTKVVLPTFILE 424
Query: 485 PLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA-GSKPFNPVLG 543
+ L+ + + + +LL +P ER++ + ++A+ A KP+NP++G
Sbjct: 425 KRSLLEMYADFMAHPDLLLAITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIG 484
Query: 544 ETYECIRE----------------------------DKGFQ--FFSEQVSHHPPISA--C 571
ET+ C E K ++ F +EQVSHHPPIS C
Sbjct: 485 ETFHCSWEVPKDRVKPKRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYC 544
Query: 572 HAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQR 631
E + V K+KF G S+ + IG + L G+ + + ++ +IL+
Sbjct: 545 ECEEKRLCVNTHVWTKSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILT-IP 603
Query: 632 WIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTV-FDRSGKAVHRLFGKWHES 690
W+E G++ I N V F ++ H + V + + V + G+W+ +
Sbjct: 604 WVELGGKVSI-NCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGT 662
Query: 691 IYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFL 750
+ + V +P + ++ P K + +R R+L
Sbjct: 663 LEFTYNNGETKVIDTTTLP-------------VYPKKIRPLEKQGPMESRNLWREVTRYL 709
Query: 751 EEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWV 797
G+++ A QK+ +E+ QR R E +P++F + + D WV
Sbjct: 710 RLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQ-EGDGWV 755
Score = 36.2 bits (82), Expect = 0.13
Identities = 35/156 (22%), Positives = 64/156 (41%), Gaps = 19/156 (12%)
Query: 18 SRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLD 77
SRS ++ GSR V G +EP ++ +L K L+GW R+F LD
Sbjct: 42 SRSAAAGLGGGGSRSSPGSVAASPSGGGGRRREPALEG--VLSKYTNLLQGWQNRYFVLD 99
Query: 78 --KGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSS--KCIDLDTEEHIYHLKVKSEEV 133
GIL+Y ++ + +K G + + +++S+ + + ++ L+ +
Sbjct: 100 FEAGILQYFVNEQS-KHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKE 158
Query: 134 FDEWVSKLRHHRMY------------RQNEIAMFPH 157
WV++LR Y R + + PH
Sbjct: 159 KQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPH 194
>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
[Homo sapiens]
Length = 847
Score = 91.3 bits (225), Expect = 3e-18
Identities = 84/336 (25%), Positives = 148/336 (44%), Gaps = 33/336 (9%)
Query: 326 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 385
+R +++ E D S S + + L + N +H N +L+ ++ + F
Sbjct: 229 KRTMIREGKEHDLSVSSDSTHVTFYGLLRANN--------LHSGDN-FQLNDSEIERQHF 279
Query: 386 DAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSGREA 441
Q++ S EN+ D D+ V S+ D D+ E + + P+ ++
Sbjct: 280 KDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTE 339
Query: 442 KSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCE 494
+S + +S +W +L+ G DLSKV +P + EP + L +L +
Sbjct: 340 QSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSD 399
Query: 495 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYECI-- 549
+++ L +AA +P R+ V + Y S +Y+ KP+NP+LGET+ C+
Sbjct: 400 YYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRCLWI 455
Query: 550 --REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHV 605
R + + +EQVSHHPPISA + +R F + K+KF+G S+ + G +
Sbjct: 456 HPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARL 515
Query: 606 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 641
T G+ + + IL G +E G + I
Sbjct: 516 TFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 551
>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
Length = 889
Score = 91.3 bits (225), Expect = 3e-18
Identities = 84/336 (25%), Positives = 148/336 (44%), Gaps = 33/336 (9%)
Query: 326 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 385
+R +++ E D S S + + L + N +H N +L+ ++ + F
Sbjct: 271 KRTMIREGKEHDLSVSSDSTHVTFYGLLRANN--------LHSGDN-FQLNDSEIERQHF 321
Query: 386 DAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSGREA 441
Q++ S EN+ D D+ V S+ D D+ E + + P+ ++
Sbjct: 322 KDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTE 381
Query: 442 KSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCE 494
+S + +S +W +L+ G DLSKV +P + EP + L +L +
Sbjct: 382 QSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSD 441
Query: 495 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYECI-- 549
+++ L +AA +P R+ V + Y S +Y+ KP+NP+LGET+ C+
Sbjct: 442 YYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRCLWI 497
Query: 550 --REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHV 605
R + + +EQVSHHPPISA + +R F + K+KF+G S+ + G +
Sbjct: 498 HPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARL 557
Query: 606 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 641
T G+ + + IL G +E G + I
Sbjct: 558 TFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 593
>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
sapiens]
Length = 626
Score = 89.7 bits (221), Expect = 1e-17
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 376 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 431
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 177 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 236
Query: 432 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 491
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 237 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 296
Query: 492 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 548
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 297 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 354
Query: 549 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 585
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 355 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 414
Query: 586 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 645
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 415 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 472
Query: 646 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 703
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 473 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 532
Query: 704 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 761
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 533 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 577
Query: 762 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 813
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 578 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 625
>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
sapiens]
Length = 571
Score = 89.7 bits (221), Expect = 1e-17
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 376 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 431
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 122 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 181
Query: 432 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 491
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 182 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 241
Query: 492 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 548
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 242 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 299
Query: 549 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 585
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 300 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 359
Query: 586 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 645
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 360 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 417
Query: 646 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 703
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 418 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 477
Query: 704 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 761
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 478 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 522
Query: 762 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 813
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 523 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 570
>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 89.7 bits (221), Expect = 1e-17
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 376 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 431
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168
Query: 432 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 491
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228
Query: 492 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 548
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286
Query: 549 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 585
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346
Query: 586 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 645
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 404
Query: 646 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 703
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 405 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 464
Query: 704 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 761
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 465 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 509
Query: 762 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 813
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 557
>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
sapiens]
Length = 558
Score = 89.7 bits (221), Expect = 1e-17
Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)
Query: 376 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 431
S + S EF+DA E S SS + I S S ++L + + L++
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168
Query: 432 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 491
D R ++ + + + +G DL+KV +P + E + L+
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228
Query: 492 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 548
+ + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286
Query: 549 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 585
+ E F +EQVSHHPPISA +AE ++ F +
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346
Query: 586 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 645
K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 404
Query: 646 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 703
+ F ++ H I +F K+ + G+W+ +Y + V+
Sbjct: 405 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 464
Query: 704 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 761
+ P+ K + + NE + S+SL D F L+ +++ A
Sbjct: 465 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 509
Query: 762 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 813
K R+E+ QR R +E ++ + R F + D + WV + L K LG +K
Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 557
>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
Length = 747
Score = 75.5 bits (184), Expect = 2e-13
Identities = 76/371 (20%), Positives = 148/371 (39%), Gaps = 60/371 (16%)
Query: 469 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 528
+G DL++V +P + E + L+ + + + +L + +RM+ + ++++
Sbjct: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438
Query: 529 SYYRA-GSKPFNPVLGETYECI------------------------------------RE 551
A KP+NP++GET+ C +
Sbjct: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498
Query: 552 DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 609
+F +EQVSHHPP+S +AE R V K+KF G S+ + +G ++L
Sbjct: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558
Query: 610 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 669
G+ + ++ + +IL+ W+E G++ + N + F ++ H +
Sbjct: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616
Query: 670 GTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEM 728
V + + V R+ G+W+ + G +Y T+ A+ +
Sbjct: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663
Query: 729 DPSSKSLLPPTDTR--FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPR 786
P K P ++R ++ L E +++A K +E+ QR R E + +
Sbjct: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721
Query: 787 FFRKSDDDSWV 797
+F K + D WV
Sbjct: 722 YFIK-EGDGWV 731
>gi|217416392 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 2 [Homo sapiens]
Length = 1493
Score = 57.4 bits (137), Expect = 5e-08
Identities = 37/113 (32%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
Query: 46 NYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSV 105
N EP + G+LLK +K W +R+F L G L Y KS +D+ R K G I++ S
Sbjct: 698 NGKNEPLEKSGYLLKM-SGKVKSWKRRWFVLKGGELLYYKSPSDVIR-KPQGHIELSASC 755
Query: 106 MSVKKSSK-CIDLDTEEHIYHLKVKSEEVFDEWVSKLRH-HRMYRQNEIAMFP 156
++ +K + L TE+H Y+L S + +EW+ L++ R+ N +++ P
Sbjct: 756 SILRGDNKQTVQLTTEKHTYYLTADSPNILEEWIKVLQNVLRVQAANPLSLQP 808
>gi|55741447 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 1 [Homo sapiens]
Length = 1364
Score = 45.4 bits (106), Expect = 2e-04
Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 3/90 (3%)
Query: 54 QKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSS 112
+ G+LLK +K W +R+F L +G + Y KS +D+ R K G +D+ V+ + S
Sbjct: 581 KSGYLLKMGS-QVKTWKRRWFVLRQGQIMYYKSPSDVIR-KPQGQVDLNSRCQIVRGEGS 638
Query: 113 KCIDLDTEEHIYHLKVKSEEVFDEWVSKLR 142
+ L +E+ Y+L S + +EW+ L+
Sbjct: 639 QTFQLISEKKTYYLTADSPSLLEEWIRVLQ 668
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 44.3 bits (103), Expect = 5e-04
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 4 DEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRK 63
++K L + L+ S Q SRQ + + + L+G Y E +KG+LLKK
Sbjct: 282 EKKQLTALRDLIKSSLQLDQKEDSQ-SRQGGYSMHQ-LQGNKEYGSE---KKGYLLKKSD 336
Query: 64 WPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVK---KSSKCIDLDTE 120
K W +R + GIL + + ++ + KL+ L VK + K DL +
Sbjct: 337 GIRKVWQRRKCSVKNGILTISHATSNRQPAKLN------LLTCQVKPNAEDKKSFDLISH 390
Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHR 145
YH + + E+ + W+S L + +
Sbjct: 391 NRTYHFQAEDEQDYVAWISVLTNSK 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,022,720
Number of Sequences: 37866
Number of extensions: 1461604
Number of successful extensions: 5521
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 5236
Number of HSP's gapped (non-prelim): 290
length of query: 820
length of database: 18,247,518
effective HSP length: 111
effective length of query: 709
effective length of database: 14,044,392
effective search space: 9957473928
effective search space used: 9957473928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.