BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21735582 oxysterol-binding protein-like protein 3 isoform c [Homo sapiens] (851 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21735582 oxysterol-binding protein-like protein 3 isoform c [... 1737 0.0 gi|14149704 oxysterol-binding protein-like protein 3 isoform a [... 1719 0.0 gi|21735584 oxysterol-binding protein-like protein 3 isoform d [... 1657 0.0 gi|21735580 oxysterol-binding protein-like protein 3 isoform b [... 1639 0.0 gi|14210532 oxysterol-binding protein-like protein 6 isoform a [... 1011 0.0 gi|22035612 oxysterol-binding protein-like protein 6 isoform b [... 997 0.0 gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] 802 0.0 gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa... 296 5e-80 gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [... 293 4e-79 gi|4505531 oxysterol binding protein [Homo sapiens] 293 5e-79 gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa... 291 1e-78 gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H... 289 9e-78 gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 266 5e-71 gi|14149740 oxysterol-binding protein-like protein 5 isoform a [... 106 8e-23 gi|221136766 oxysterol-binding protein-like protein 5 isoform b ... 106 8e-23 gi|22035609 oxysterol-binding protein-like protein 5 isoform b [... 106 8e-23 gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 91 3e-18 gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 91 3e-18 gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi... 91 3e-18 gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap... 90 1e-17 gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap... 90 1e-17 gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap... 90 1e-17 gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap... 90 1e-17 gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap... 90 1e-17 gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap... 90 1e-17 gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap... 90 1e-17 gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] 75 2e-13 gi|217416392 pleckstrin homology domain containing, family H (wi... 57 6e-08 gi|55741447 pleckstrin homology domain containing, family H (wit... 45 2e-04 gi|46094081 development and differentiation enhancing factor 1 [... 44 5e-04 >gi|21735582 oxysterol-binding protein-like protein 3 isoform c [Homo sapiens] Length = 851 Score = 1737 bits (4498), Expect = 0.0 Identities = 851/851 (100%), Positives = 851/851 (100%) Query: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK Sbjct: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60 Query: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE Sbjct: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120 Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180 Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240 Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR Sbjct: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300 Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK Sbjct: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360 Query: 361 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 420 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE Sbjct: 361 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 420 Query: 421 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 480 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL Sbjct: 421 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 480 Query: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP Sbjct: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540 Query: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS Sbjct: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600 Query: 601 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 660 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG Sbjct: 601 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 660 Query: 661 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 720 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE Sbjct: 661 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 720 Query: 721 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 780 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF Sbjct: 721 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 780 Query: 781 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 840 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL Sbjct: 781 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 840 Query: 841 GFSKLDHPVLW 851 GFSKLDHPVLW Sbjct: 841 GFSKLDHPVLW 851 >gi|14149704 oxysterol-binding protein-like protein 3 isoform a [Homo sapiens] Length = 887 Score = 1719 bits (4451), Expect = 0.0 Identities = 851/887 (95%), Positives = 851/887 (95%), Gaps = 36/887 (4%) Query: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK Sbjct: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60 Query: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE Sbjct: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120 Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180 Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240 Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR Sbjct: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300 Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK Sbjct: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360 Query: 361 LKQLMEQDASSSPSAQVIGLKNALSS---------------------------------- 386 LKQLMEQDASSSPSAQVIGLKNALSS Sbjct: 361 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 420 Query: 387 --ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 444 ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD Sbjct: 421 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 480 Query: 445 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 504 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL Sbjct: 481 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 540 Query: 505 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 564 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA Sbjct: 541 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 600 Query: 565 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 624 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK Sbjct: 601 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 660 Query: 625 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 684 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV Sbjct: 661 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 720 Query: 685 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 744 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE Sbjct: 721 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 780 Query: 745 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 804 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR Sbjct: 781 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 840 Query: 805 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 851 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW Sbjct: 841 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 887 >gi|21735584 oxysterol-binding protein-like protein 3 isoform d [Homo sapiens] Length = 820 Score = 1657 bits (4292), Expect = 0.0 Identities = 820/851 (96%), Positives = 820/851 (96%), Gaps = 31/851 (3%) Query: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK Sbjct: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60 Query: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE Sbjct: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120 Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180 Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240 Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300 QSMDVLHRTYSAPAINAIQ VPKPFSGPVR Sbjct: 241 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR 269 Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK Sbjct: 270 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 329 Query: 361 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 420 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE Sbjct: 330 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 389 Query: 421 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 480 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL Sbjct: 390 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 449 Query: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP Sbjct: 450 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 509 Query: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS Sbjct: 510 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 569 Query: 601 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 660 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG Sbjct: 570 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 629 Query: 661 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 720 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE Sbjct: 630 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 689 Query: 721 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 780 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF Sbjct: 690 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 749 Query: 781 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 840 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL Sbjct: 750 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 809 Query: 841 GFSKLDHPVLW 851 GFSKLDHPVLW Sbjct: 810 GFSKLDHPVLW 820 >gi|21735580 oxysterol-binding protein-like protein 3 isoform b [Homo sapiens] Length = 856 Score = 1639 bits (4245), Expect = 0.0 Identities = 820/887 (92%), Positives = 820/887 (92%), Gaps = 67/887 (7%) Query: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK Sbjct: 1 MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60 Query: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE Sbjct: 61 KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120 Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180 Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240 Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300 QSMDVLHRTYSAPAINAIQ VPKPFSGPVR Sbjct: 241 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR 269 Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK Sbjct: 270 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 329 Query: 361 LKQLMEQDASSSPSAQVIGLKNALSS---------------------------------- 386 LKQLMEQDASSSPSAQVIGLKNALSS Sbjct: 330 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 389 Query: 387 --ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 444 ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD Sbjct: 390 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 449 Query: 445 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 504 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL Sbjct: 450 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 509 Query: 505 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 564 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA Sbjct: 510 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 569 Query: 565 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 624 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK Sbjct: 570 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 629 Query: 625 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 684 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV Sbjct: 630 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 689 Query: 685 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 744 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE Sbjct: 690 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 749 Query: 745 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 804 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR Sbjct: 750 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 809 Query: 805 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 851 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW Sbjct: 810 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 856 >gi|14210532 oxysterol-binding protein-like protein 6 isoform a [Homo sapiens] Length = 934 Score = 1011 bits (2613), Expect = 0.0 Identities = 515/935 (55%), Positives = 661/935 (70%), Gaps = 85/935 (9%) Query: 1 MMSDEKNLGVSQKLVSPSR--STSSCSSKQGSRQ-------------------------- 32 M SDEK + + K +P+ ++SS SS++ SRQ Sbjct: 1 MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60 Query: 33 -------DSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAK 85 DSWE++EGL+ Q+P +GF+LKKRKWPLKGWHKRFF LD G+LKY+K Sbjct: 61 VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120 Query: 86 SQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145 + DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVKS++ FD WVSKLRHHR Sbjct: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180 Query: 146 MYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SSISKQNLFQTGSNVSFS 202 +YRQNEI P + + H F ++ +SS S+ K +S Q+ +++ + Sbjct: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240 Query: 203 CG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAINAIQGG 261 C G+++V WLQ SE+M++C++DLAHC + LVE+S+LLQ++++L RT SAP +Q Sbjct: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300 Query: 262 SFESPKKEKRSHRRWRSRAIGKDAKGTLQVP-KPFSGPVRLHSSNPNL-STLDFGEEKNY 319 + KK+KR RRWR++++ KD K LQVP PVRLHSSNPNL + ++F ++ Sbjct: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360 Query: 320 -SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQV 377 +D E+S++++K+QE+ C IA KV+ L+SAFN ++ E+EKLKQ++ EQD S S Q+ Sbjct: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420 Query: 378 IGLKNALS-----------------SEN-------------SRDENRALVH-------QL 400 L+ +LS SE+ S DE +H Q+ Sbjct: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQV 480 Query: 401 SNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQ 460 +NESRLS+++S+SEFFDAQEVLLS SSSENE SDD+SY+SD+SDN+S DN S + RQ Sbjct: 481 ANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQ 540 Query: 461 TLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTL 520 L L G ++ RR CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTL Sbjct: 541 ILNGELTGGA-FRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTL 599 Query: 521 QRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECI 580 Q LCEE+EYSELLDKA++ P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECI Sbjct: 600 QHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI 659 Query: 581 REDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 640 REDKGF+FFSEQVSHHPPISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP Sbjct: 660 REDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 719 Query: 641 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 700 +GD++ WNKVT+CIHNILSG+RWIEHYGE+ I+N C CK+ F+K YW++N +E++ Sbjct: 720 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 779 Query: 701 GTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMD 760 G V D+ GKAV+RLFGKWHE +YCG S+ C+WR MP YE YY FT+FA+ELNE+D Sbjct: 780 GVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELD 839 Query: 761 PSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 820 P K LLPPTD RFRPDQRFLEEGNLE A +KQR+E+LQR RRR +EEN++EH P+FF+ Sbjct: 840 PVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFK 899 Query: 821 KSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW 851 K D ++WVSN TY ELRKD GFSK+D PVLW Sbjct: 900 KVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934 >gi|22035612 oxysterol-binding protein-like protein 6 isoform b [Homo sapiens] Length = 938 Score = 997 bits (2577), Expect = 0.0 Identities = 506/916 (55%), Positives = 647/916 (70%), Gaps = 81/916 (8%) Query: 10 VSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGW 69 VS++L+ P S DSWE++EGL+ Q+P +GF+LKKRKWPLKGW Sbjct: 30 VSRQLLEPEPVPLS------KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGW 83 Query: 70 HKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVK 129 HKRFF LD G+LKY+K+ DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVK Sbjct: 84 HKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVK 143 Query: 130 SEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SS 186 S++ FD WVSKLRHHR+YRQNEI P + + H F ++ +SS S+ K +S Sbjct: 144 SQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNS 203 Query: 187 ISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDV 245 Q+ +++ +C G+++V WLQ SE+M++C++DLAHC + LVE+S+LLQ++++ Sbjct: 204 FPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEI 263 Query: 246 LHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSG-------- 297 L RT SAP +Q + KK+KR RRWR++++ KD K LQ P G Sbjct: 264 LQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRR 323 Query: 298 ------------------PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLC 337 PVRLHSSNPNL + ++F ++ +D E+S++++K+QE+ C Sbjct: 324 QRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFC 383 Query: 338 HIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALS----------- 385 IA KV+ L+SAFN ++ E+EKLKQ++ EQD S S Q+ L+ +LS Sbjct: 384 LIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRS 443 Query: 386 ------SEN-------------SRDENRALVH-------QLSNESRLSITDSLSEFFDAQ 419 SE+ S DE +H Q++NESRLS+++S+SEFFDAQ Sbjct: 444 RLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQ 503 Query: 420 EVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTC 479 EVLLS SSSENE SDD+SY+SD+SDN+S DN S + RQ L L G ++ RR C Sbjct: 504 EVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGA-FRNGRRAC 562 Query: 480 LPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQI 539 LPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTLQ LCEE+EYSELLDKA++ Sbjct: 563 LPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASET 622 Query: 540 PSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPI 599 P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECIREDKGF+FFSEQVSHHPPI Sbjct: 623 DDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPI 682 Query: 600 SACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILS 659 SACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP +GD++ WNKVT+CIHNILS Sbjct: 683 SACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILS 742 Query: 660 GQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWH 719 G+RWIEHYGE+ I+N C CK+ F+K YW++N +E++G V D+ GKAV+RLFGKWH Sbjct: 743 GRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWH 802 Query: 720 ESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQR 779 E +YCG S+ C+WR MP YE YY FT+FA+ELNE+DP K LLPPTD RFRPDQR Sbjct: 803 EGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQR 862 Query: 780 FLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTYLE 835 FLEEGNLE A +KQR+E+LQR RRR +EEN++EH P+FF+K D ++WVSN TY E Sbjct: 863 FLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWE 922 Query: 836 LRKDLGFSKLDHPVLW 851 LRKD GFSK+D PVLW Sbjct: 923 LRKDPGFSKVDSPVLW 938 >gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens] Length = 842 Score = 802 bits (2072), Expect = 0.0 Identities = 430/870 (49%), Positives = 552/870 (63%), Gaps = 74/870 (8%) Query: 17 PSRSTSSCSSKQGSRQDSWEVVE------GLRGEMNYTQEPPVQKGFLLKKRKWPLKGWH 70 P + SS S + WEVVE G G M P Q+G LLKKRKWPLKGWH Sbjct: 12 PESAQSSKPSSAQQASELWEVVEEPRVRLGTEGVM-----PERQEGHLLKKRKWPLKGWH 66 Query: 71 KRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS 130 KR+F L+ GIL YA ++ DI + KLHG IDV LSVMS+ K ++ IDLDTE++IYHLK+KS Sbjct: 67 KRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS 126 Query: 131 EEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQ 190 +++F WV++LR HR+ + D G S + RK Sbjct: 127 QDLFQSWVAQLRAHRLAHR-------------------LDMPRGSLPSTAHRKVPGAQ-- 165 Query: 191 NLFQTGSNVSF--SCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHR 248 T + S G +V WL+ S+ +++CS +L+ C L E+ +LLQS++ LHR Sbjct: 166 --LPTAATASALPGLGPREKVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQSLESLHR 223 Query: 249 TYSAPAINAIQGG-SFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVRLHSSNPN 307 SAP I Q + E PKK KR+ R W +++ KD RLH S PN Sbjct: 224 IPSAPVIPTHQASVTTERPKKGKRTSRMWCTQSFAKD--------DTIGRVGRLHGSVPN 275 Query: 308 LSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLK----- 362 LS + + + G + +++ +Q +A KV+ +L S ++ ER++L+ Sbjct: 276 LSRYLESRDSSGTRGLPPT-DYAHLQRSFWALAQKVHSSLSSVLAALTMERDQLRDMHQG 334 Query: 363 ----------------QLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRL 406 +L SS +A N E + R L QLS S L Sbjct: 335 SELSRMGVSEASTGQRRLHSLSTSSDTTADSFSSLNPEEQEALYMKGRELTPQLSQTSIL 394 Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDD-SYVSDISDNLSLDNLSNDLDNERQTLGPV 465 S+ DS +EFFDA EVLLS SSSENE S+++ S S+I+ +LS + L DL + Sbjct: 395 SLADSHTEFFDACEVLLSASSSENEGSEEEESCTSEITTSLSEEML--DLRGAERCQKGG 452 Query: 466 LDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCE 525 GR RR CLPA +++SLWNILRNNIGKDLSKV+MPV+LNEPLNTLQRLCE Sbjct: 453 CVPGRPMGPPRRRCLPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCE 512 Query: 526 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKG 585 ELEYS LLD+A++I P ERMVY+AAFA+SAY+S+Y+RAG KPFNPVLGETYEC R D+G Sbjct: 513 ELEYSSLLDQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRG 572 Query: 586 FQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHF 645 F+F SEQVSHHPPISACHAES NF FWQD++WKNKFWGKS+EIVP+GT +V+LP FGDHF Sbjct: 573 FRFISEQVSHHPPISACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHF 632 Query: 646 EWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFD 705 EWNKVTSCIHN+LSGQRWIEHYGE++I+N D SC+CK+ F KAKYWS+N HE++G V Sbjct: 633 EWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLS 692 Query: 706 RSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKS 765 RSG+ +HRLFGKWHE +Y G C+W+ N MP +E+ + FTQFALELNE+ K Sbjct: 693 RSGRVLHRLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKR 752 Query: 766 LLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDD 825 LP TDTR RPDQR+LEEGN++ AE QK+RIEQLQR+RR+V+EEN++ HQ RFFR+ D Sbjct: 753 SLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDS 812 Query: 826 S----WVSNGTYLELRKDLGFSKLDHPVLW 851 S WV+N TY LR + G+ +D VLW Sbjct: 813 SGKEWWVTNNTYWRLRAEPGYGNMDGAVLW 842 >gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sapiens] Length = 950 Score = 296 bits (758), Expect = 5e-80 Identities = 182/523 (34%), Positives = 271/523 (51%), Gaps = 79/523 (15%) Query: 379 GLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSY 438 G++N E +++N+ L L + +E + ++ L+ S + +S+D+ Y Sbjct: 427 GVRN-FKLEQEQEKNKILSEALETLA--------TEHHELEQSLVKGSPPASILSEDEFY 477 Query: 439 --VSDISDNLSLDNL----SNDLDNERQTLGPVLDSGREAKS------------RRRTCL 480 +SD SL L + + E + LG E K + RT L Sbjct: 478 DALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSL 537 Query: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540 P+P S ++ S+W+ILR IG +LSK+ MPV NEPL+ LQRL E +E++ L+ KA+ + Sbjct: 538 PSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLS 597 Query: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600 P+ERM VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+ SEQVSHHPPIS Sbjct: 598 DPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVSHHPPIS 656 Query: 601 ACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNIL 658 A HAE N F+F + K KFWGKS+E P GT + L + + W T C+HNI+ Sbjct: 657 AFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNII 716 Query: 659 SGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKW 718 G+ WIE YG + I N H C +NF + H++EG + D+S K + L+GKW Sbjct: 717 VGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKW 775 Query: 719 HESIYCGGGSS-------------------------------------------SACVWR 735 E +Y ++ S +WR Sbjct: 776 TECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWR 835 Query: 736 ANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQR 795 P P Q Y+FT FA+ LNE+D +S++P TD R RPD R +E G +++A +K+R Sbjct: 836 IAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKR 895 Query: 796 IEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 833 +E+ QR R+ ++ + + R+F + + W+ +G+Y Sbjct: 896 LEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 938 Score = 32.3 bits (72), Expect = 1.9 Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 17/133 (12%) Query: 68 GWHKRFFYLDKGILKYAKSQTD-IEREKLHGCIDVGLSVMSVKKSSKCI----DLDTEEH 122 GW + L+ G+L + + Q D + GC + +V +VK + C+ D H Sbjct: 250 GWRLFWVVLEHGVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTDSCLFFIKCFDDTIH 309 Query: 123 IYHLKVKS-EEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISS 181 + + S ++ ++W+ + H Y H+ S +TD S + Sbjct: 310 GFRVPKNSLQQSREDWLEAIEEHSAYS-----------THYCSQDQLTDEEEEDTVSAAD 358 Query: 182 RKRSSISKQNLFQ 194 K+S Q+ Q Sbjct: 359 LKKSLEKAQSCQQ 371 >gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [Homo sapiens] Length = 480 Score = 293 bits (751), Expect = 4e-79 Identities = 180/475 (37%), Positives = 251/475 (52%), Gaps = 63/475 (13%) Query: 414 EFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 473 EFFDA S +SS E S+ + V+ + D + N ER P ++G + Sbjct: 6 EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGER----PSQENGIQ-- 58 Query: 474 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 533 + RT LPAP S S+ S+W IL+ +G +LSK+ MP+ NEPL+ LQR+ E +E+ L+ Sbjct: 59 -KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117 Query: 534 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 593 +A+ P PLERM VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQV Sbjct: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176 Query: 594 SHHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVT 651 SHHPPISA H+E N F+F + K KFWGKS+E P GT + L + + W T Sbjct: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236 Query: 652 SCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAV 711 C+HN++ G+ WIE YG + I N H C ++F + H++EG + D++ K + Sbjct: 237 CCVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295 Query: 712 HRLFGKWHESIY----------------------------CGGGSS-------------- 729 ++GKW E ++ G S Sbjct: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355 Query: 730 ----SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGN 785 S +WR N P Q Y+FT F + LNE++ + LPPTD R RPD R +E GN Sbjct: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415 Query: 786 LEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 835 ++ A +K+R+E+ QRE RR + E Q R+F ++ W+ G Y E Sbjct: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 470 >gi|4505531 oxysterol binding protein [Homo sapiens] Length = 807 Score = 293 bits (750), Expect = 5e-79 Identities = 171/430 (39%), Positives = 251/430 (58%), Gaps = 45/430 (10%) Query: 401 SNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQ 460 S + +S D +EFFDA E++ P + ++ + S +S S ++SLD + + Sbjct: 345 SGKGDMSDEDDENEFFDAPEIITMPENLGHKRTG--SNISGASSDISLD------EQYKH 396 Query: 461 TLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTL 520 L E K +RT +P + +++LW+I++N IGK+LSK+ MPV NEPL+ L Sbjct: 397 QL-------EETKKEKRTRIPYK--PNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSML 447 Query: 521 QRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECI 580 QRL E+LEY ELLD+AA+ + LE++ YVAAF +S+Y+++ +R SKPFNP+LGET+E Sbjct: 448 QRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRT-SKPFNPLLGETFELD 506 Query: 581 R-EDKGFQFFSEQVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTL 638 R E+ G++ EQVSHHPP +A HAES+N + Q+++ +KF GK + I+P+GT H Sbjct: 507 RLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIF 566 Query: 639 PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AH 697 G H+ W KVT+ +HNI+ G+ WI+ GEI I N H C + F+ Y+S + A Sbjct: 567 HATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVN-HKTGDKCNLKFVPYSYFSRDVAR 625 Query: 698 EIEGTVFDRSGKAVHRLFGKWHESIYC---------GGG----------SSSACVWRANP 738 ++ G V D SGK L G W E + C GG S +W+ NP Sbjct: 626 KVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNP 685 Query: 739 MPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQ 798 +PK E Y F++ AL LN + + PTD+R RPDQR +E G +EA +KQR+E+ Sbjct: 686 LPKNAENMYYFSELALTLNAWESGT----APTDSRLRPDQRLMENGRWDEANAEKQRLEE 741 Query: 799 LQRERRRVLE 808 QR R+ E Sbjct: 742 KQRLSRKKRE 751 Score = 46.2 bits (108), Expect = 1e-04 Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 2/88 (2%) Query: 54 QKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSK 113 ++G+L K + +KG+ +R+F L G+L Y +S+ ++ R G I++ + ++V+ S Sbjct: 91 REGWLFKWTNY-IKGYQRRWFVLSNGLLSYYRSKAEM-RHTCRGTINLATANITVEDSCN 148 Query: 114 CIDLDTEEHIYHLKVKSEEVFDEWVSKL 141 I + YHLK SE WV+ L Sbjct: 149 FIISNGGAQTYHLKASSEVERQRWVTAL 176 >gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sapiens] Length = 437 Score = 291 bits (746), Expect = 1e-78 Identities = 160/409 (39%), Positives = 229/409 (55%), Gaps = 52/409 (12%) Query: 475 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 534 + RT LP+P S ++ S+W+ILR IG +LSK+ MPV NEPL+ LQRL E +E++ L+ Sbjct: 19 KHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIH 78 Query: 535 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 594 KA+ + P+ERM VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+ SEQVS Sbjct: 79 KASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVS 137 Query: 595 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 652 HHPPISA HAE N F+F + K KFWGKS+E P GT + L + + W T Sbjct: 138 HHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTC 197 Query: 653 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 712 C+HNI+ G+ WIE YG + I N H C +NF + H++EG + D+S K + Sbjct: 198 CVHNIIVGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLC 256 Query: 713 RLFGKWHESIYCGGGSS------------------------------------------- 729 L+GKW E +Y ++ Sbjct: 257 ALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPG 316 Query: 730 SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEA 789 S +WR P P Q Y+FT FA+ LNE+D +S++P TD R RPD R +E G +++A Sbjct: 317 SVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQA 376 Query: 790 EIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 833 +K+R+E+ QR R+ ++ + + R+F + + W+ +G+Y Sbjct: 377 SEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425 >gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo sapiens] Length = 468 Score = 289 bits (739), Expect = 9e-78 Identities = 163/414 (39%), Positives = 225/414 (54%), Gaps = 55/414 (13%) Query: 475 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 534 + RT LPAP S S+ S+W IL+ +G +LSK+ MP+ NEPL+ LQR+ E +E+ L+ Sbjct: 47 KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 106 Query: 535 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 594 +A+ P PLERM VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQVS Sbjct: 107 RASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVS 165 Query: 595 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 652 HHPPISA H+E N F+F + K KFWGKS+E P GT + L + + W T Sbjct: 166 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 225 Query: 653 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 712 C+HN++ G+ WIE YG + I N H C ++F + H++EG + D++ K + Sbjct: 226 CVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF 284 Query: 713 RLFGKWHESIY----------------------------CGGGSS--------------- 729 ++GKW E ++ G S Sbjct: 285 MIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQV 344 Query: 730 ---SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNL 786 S +WR N P Q Y+FT F + LNE++ + LPPTD R RPD R +E GN+ Sbjct: 345 IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNM 404 Query: 787 EEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 835 + A +K+R+E+ QRE RR + E Q R+F ++ W+ G Y E Sbjct: 405 DLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 458 >gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] Length = 916 Score = 266 bits (681), Expect = 5e-71 Identities = 173/480 (36%), Positives = 264/480 (55%), Gaps = 45/480 (9%) Query: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDEN--RALVHQ--LSNESRLSITDSL 412 +R L++ +EQ A S L+ A S R N ++ + L+ + S D Sbjct: 395 QRVHLEETIEQLAKQHNS-----LERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDED 449 Query: 413 SEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREA 472 +E+FDA E S + E +D + S+D S D + +L P S Sbjct: 450 TEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSS---- 505 Query: 473 KSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSEL 532 K +RR +P + +++LW+I++N IG++LS++ MPV NEPL+ LQRL E+LEY L Sbjct: 506 KVKRRVRIPNK--PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHL 563 Query: 533 LDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIR-EDKGFQFFSE 591 LDKA S +E+M VAAF++S+Y+++ +R +KPFNP+LGET+E R +D G + E Sbjct: 564 LDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDMGLRSLCE 622 Query: 592 QVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKV 650 QVSHHPP +A + S++ + WQ++ +KF GK + I+P+G H+ G+H+ W K Sbjct: 623 QVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKS 682 Query: 651 TSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AHEIEGTVFDRSGK 709 TS +HNI+ G+ WI+ G+I I N H + C++ F+ Y+S A ++ G V D GK Sbjct: 683 TSTVHNIIVGKLWIDQSGDIEIVN-HKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGK 741 Query: 710 AVHRLFGKWHESIYCG--------------------GGSSSACVWRANPMPKGYEQYYSF 749 A + L G W E + C S+ +W+ P+P+ E Y F Sbjct: 742 AHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYF 801 Query: 750 TQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR-ERRRVLE 808 ++ AL LNE + + PTD+R RPDQR +E+G +EA +KQR+E+ QR RRR LE Sbjct: 802 SELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLE 857 Score = 43.5 bits (101), Expect = 8e-04 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%) Query: 55 KGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCI-DVGLSVMSVKKSSK 113 +G+LLK + LKG+ +R+F L G+L Y ++Q E H C + LS + Sbjct: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQ----GEMAHTCRGTINLSTAHIDTEDS 240 Query: 114 C-IDLDTEEHIYHLKVKSEEVFDEWVSKL 141 C I L + YHLK SE +W++ L Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITAL 269 >gi|14149740 oxysterol-binding protein-like protein 5 isoform a [Homo sapiens] Length = 879 Score = 106 bits (265), Expect = 8e-23 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%) Query: 486 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 543 S N SL W +L+ G DLS+V +P + EP + L +L + +++LL +AA Sbjct: 364 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 423 Query: 544 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 596 RM V + Y S +Y+ KP+NP+LGET+ C + D + +EQVSHH Sbjct: 424 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 479 Query: 597 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 654 PP+SA H +R F + K++F+G S+ + G +T + + + Sbjct: 480 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 539 Query: 655 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 711 IL G +E G++ I+ ++ ++ F ++ ST+ ++I G + SG+ V Sbjct: 540 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 596 Query: 712 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 769 L G W ++ G SSA W P G + Q + L E L Sbjct: 597 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 650 Query: 770 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 819 ++ R + +G+ A +K +E+ QR+R R +E+ + +P+ F Sbjct: 651 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 696 >gi|221136766 oxysterol-binding protein-like protein 5 isoform b [Homo sapiens] Length = 811 Score = 106 bits (265), Expect = 8e-23 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%) Query: 486 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 543 S N SL W +L+ G DLS+V +P + EP + L +L + +++LL +AA Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355 Query: 544 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 596 RM V + Y S +Y+ KP+NP+LGET+ C + D + +EQVSHH Sbjct: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411 Query: 597 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 654 PP+SA H +R F + K++F+G S+ + G +T + + + Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471 Query: 655 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 711 IL G +E G++ I+ ++ ++ F ++ ST+ ++I G + SG+ V Sbjct: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528 Query: 712 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 769 L G W ++ G SSA W P G + Q + L E L Sbjct: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582 Query: 770 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 819 ++ R + +G+ A +K +E+ QR+R R +E+ + +P+ F Sbjct: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628 >gi|22035609 oxysterol-binding protein-like protein 5 isoform b [Homo sapiens] Length = 811 Score = 106 bits (265), Expect = 8e-23 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%) Query: 486 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 543 S N SL W +L+ G DLS+V +P + EP + L +L + +++LL +AA Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355 Query: 544 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 596 RM V + Y S +Y+ KP+NP+LGET+ C + D + +EQVSHH Sbjct: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411 Query: 597 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 654 PP+SA H +R F + K++F+G S+ + G +T + + + Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471 Query: 655 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 711 IL G +E G++ I+ ++ ++ F ++ ST+ ++I G + SG+ V Sbjct: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528 Query: 712 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 769 L G W ++ G SSA W P G + Q + L E L Sbjct: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582 Query: 770 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 819 ++ R + +G+ A +K +E+ QR+R R +E+ + +P+ F Sbjct: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628 >gi|51243032 oxysterol-binding protein-like protein 8 isoform b [Homo sapiens] Length = 847 Score = 91.3 bits (225), Expect = 3e-18 Identities = 84/336 (25%), Positives = 148/336 (44%), Gaps = 33/336 (9%) Query: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 416 +R +++ E D S S + + L + N +H N +L+ ++ + F Sbjct: 229 KRTMIREGKEHDLSVSSDSTHVTFYGLLRANN--------LHSGDN-FQLNDSEIERQHF 279 Query: 417 DAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSGREA 472 Q++ S EN+ D D+ V S+ D D+ E + + P+ ++ Sbjct: 280 KDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTE 339 Query: 473 KSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCE 525 +S + +S +W +L+ G DLSKV +P + EP + L +L + Sbjct: 340 QSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSD 399 Query: 526 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYECI-- 580 +++ L +AA +P R+ V + Y S +Y+ KP+NP+LGET+ C+ Sbjct: 400 YYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRCLWI 455 Query: 581 --REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHV 636 R + + +EQVSHHPPISA + +R F + K+KF+G S+ + G + Sbjct: 456 HPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARL 515 Query: 637 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 672 T G+ + + IL G +E G + I Sbjct: 516 TFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 551 >gi|18079218 oxysterol-binding protein-like protein 8 isoform a [Homo sapiens] Length = 889 Score = 91.3 bits (225), Expect = 3e-18 Identities = 84/336 (25%), Positives = 148/336 (44%), Gaps = 33/336 (9%) Query: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 416 +R +++ E D S S + + L + N +H N +L+ ++ + F Sbjct: 271 KRTMIREGKEHDLSVSSDSTHVTFYGLLRANN--------LHSGDN-FQLNDSEIERQHF 321 Query: 417 DAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSGREA 472 Q++ S EN+ D D+ V S+ D D+ E + + P+ ++ Sbjct: 322 KDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTE 381 Query: 473 KSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCE 525 +S + +S +W +L+ G DLSKV +P + EP + L +L + Sbjct: 382 QSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSD 441 Query: 526 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYECI-- 580 +++ L +AA +P R+ V + Y S +Y+ KP+NP+LGET+ C+ Sbjct: 442 YYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRCLWI 497 Query: 581 --REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHV 636 R + + +EQVSHHPPISA + +R F + K+KF+G S+ + G + Sbjct: 498 HPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARL 557 Query: 637 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 672 T G+ + + IL G +E G + I Sbjct: 558 TFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 593 >gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapiens] Length = 764 Score = 91.3 bits (225), Expect = 3e-18 Identities = 117/568 (20%), Positives = 222/568 (39%), Gaps = 88/568 (15%) Query: 300 RLHSSNPNLSTLDFGEEKNYSDGSET---SSEFSKMQEDLCHIAHKVYFTLRSAFNIMSA 356 +LH ++ ++ G++KN E+ S + + +DL + TL ++ Sbjct: 237 QLHEVREMMNQVE-GQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLNL 295 Query: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 416 ++ + Q + S ++G + S + +N L S + ++ Sbjct: 296 LQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWA------- 348 Query: 417 DAQEVLLSPSSSENEISDDDSYVSDISDNLSL--DNLSNDLDNERQTLGPVLDSGREAKS 474 + P+S+E+E + + L L D S++ D E LG + D Sbjct: 349 ------ILPNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQ------ 396 Query: 475 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 534 +I L I + +G DL+KV +P + E + L+ + + + +LL Sbjct: 397 -------------RSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLL 443 Query: 535 KAAQIPSPLERMVYVAAFAISAYASSYYRA-GSKPFNPVLGETYECIRE----------- 582 +P ER++ + ++A+ A KP+NP++GET+ C E Sbjct: 444 AITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRT 503 Query: 583 -----------------DKGFQ--FFSEQVSHHPPISA--CHAESRNFVFWQDVRWKNKF 621 K ++ F +EQVSHHPPIS C E + V K+KF Sbjct: 504 ASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKF 563 Query: 622 WGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCY 681 G S+ + IG + L G+ + + ++ +IL+ W+E G++ I N Sbjct: 564 MGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILT-IPWVELGGKVSI-NCAKTGYS 621 Query: 682 CKVNFIKAKYWSTNAHEIEGTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMP 740 V F ++ H + V + + V + G+W+ ++ + V +P Sbjct: 622 ATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLP 681 Query: 741 KGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQ 800 + ++ P K + +R R+L G+++ A QK+ +E+ Q Sbjct: 682 -------------VYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQ 728 Query: 801 RERRRVLEENHVEHQPRFFRKSDDDSWV 828 R R E +P++F + + D WV Sbjct: 729 RVEERKRENLRTPWKPKYFIQ-EGDGWV 755 Score = 36.2 bits (82), Expect = 0.13 Identities = 35/156 (22%), Positives = 64/156 (41%), Gaps = 19/156 (12%) Query: 18 SRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLD 77 SRS ++ GSR V G +EP ++ +L K L+GW R+F LD Sbjct: 42 SRSAAAGLGGGGSRSSPGSVAASPSGGGGRRREPALEG--VLSKYTNLLQGWQNRYFVLD 99 Query: 78 --KGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSS--KCIDLDTEEHIYHLKVKSEEV 133 GIL+Y ++ + +K G + + +++S+ + + ++ L+ + Sbjct: 100 FEAGILQYFVNEQS-KHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKE 158 Query: 134 FDEWVSKLRHHRMY------------RQNEIAMFPH 157 WV++LR Y R + + PH Sbjct: 159 KQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPH 194 >gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sapiens] Length = 736 Score = 89.7 bits (221), Expect = 1e-17 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%) Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462 S + S EF+DA E S SS + I S S ++L + + L++ Sbjct: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346 Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522 D R ++ + + + +G DL+KV +P + E + L+ Sbjct: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406 Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579 + + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C Sbjct: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464 Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616 + E F +EQVSHHPPISA +AE ++ F + Sbjct: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524 Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676 K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N Sbjct: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582 Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734 + F ++ H I +F K+ + G+W+ +Y + V+ Sbjct: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642 Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792 + P+ K + + NE + S+SL D F L+ +++ A Sbjct: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687 Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844 K R+E+ QR R +E ++ + R F + D + WV + L K LG +K Sbjct: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735 Score = 38.9 bits (89), Expect = 0.020 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%) Query: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117 KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + + Sbjct: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70 Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171 ++ +H + + + ++W+ L H + Q + F V F T D+ Sbjct: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128 >gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sapiens] Length = 746 Score = 89.7 bits (221), Expect = 1e-17 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%) Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462 S + S EF+DA E S SS + I S S ++L + + L++ Sbjct: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356 Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522 D R ++ + + + +G DL+KV +P + E + L+ Sbjct: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416 Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579 + + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C Sbjct: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474 Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616 + E F +EQVSHHPPISA +AE ++ F + Sbjct: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534 Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676 K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N Sbjct: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 592 Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734 + F ++ H I +F K+ + G+W+ +Y + V+ Sbjct: 593 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 652 Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792 + P+ K + + NE + S+SL D F L+ +++ A Sbjct: 653 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 697 Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844 K R+E+ QR R +E ++ + R F + D + WV + L K LG +K Sbjct: 698 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 745 Score = 38.5 bits (88), Expect = 0.027 Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 5/84 (5%) Query: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117 KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + + Sbjct: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70 Query: 118 DTEEHIYHLKVKSEEVFDEWVSKL 141 ++ +H + + + ++W+ L Sbjct: 71 TVDQKTFHFQARDADEREKWIHAL 94 >gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sapiens] Length = 723 Score = 89.7 bits (221), Expect = 1e-17 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%) Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462 S + S EF+DA E S SS + I S S ++L + + L++ Sbjct: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333 Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522 D R ++ + + + +G DL+KV +P + E + L+ Sbjct: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393 Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579 + + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C Sbjct: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451 Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616 + E F +EQVSHHPPISA +AE ++ F + Sbjct: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511 Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676 K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N Sbjct: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 569 Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734 + F ++ H I +F K+ + G+W+ +Y + V+ Sbjct: 570 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 629 Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792 + P+ K + + NE + S+SL D F L+ +++ A Sbjct: 630 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 674 Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844 K R+E+ QR R +E ++ + R F + D + WV + L K LG +K Sbjct: 675 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 722 Score = 38.9 bits (89), Expect = 0.020 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%) Query: 63 KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117 KW +KGW R+F LD G+L Y S+ + R GC+ + +V+ + + + Sbjct: 11 KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70 Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171 ++ +H + + + ++W+ L H + Q + F V F T D+ Sbjct: 71 TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128 >gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sapiens] Length = 626 Score = 89.7 bits (221), Expect = 1e-17 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%) Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462 S + S EF+DA E S SS + I S S ++L + + L++ Sbjct: 177 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 236 Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522 D R ++ + + + +G DL+KV +P + E + L+ Sbjct: 237 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 296 Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579 + + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C Sbjct: 297 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 354 Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616 + E F +EQVSHHPPISA +AE ++ F + Sbjct: 355 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 414 Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676 K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N Sbjct: 415 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 472 Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734 + F ++ H I +F K+ + G+W+ +Y + V+ Sbjct: 473 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 532 Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792 + P+ K + + NE + S+SL D F L+ +++ A Sbjct: 533 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 577 Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844 K R+E+ QR R +E ++ + R F + D + WV + L K LG +K Sbjct: 578 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 625 >gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sapiens] Length = 571 Score = 89.7 bits (221), Expect = 1e-17 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%) Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462 S + S EF+DA E S SS + I S S ++L + + L++ Sbjct: 122 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 181 Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522 D R ++ + + + +G DL+KV +P + E + L+ Sbjct: 182 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 241 Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579 + + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C Sbjct: 242 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 299 Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616 + E F +EQVSHHPPISA +AE ++ F + Sbjct: 300 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 359 Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676 K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N Sbjct: 360 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 417 Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734 + F ++ H I +F K+ + G+W+ +Y + V+ Sbjct: 418 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 477 Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792 + P+ K + + NE + S+SL D F L+ +++ A Sbjct: 478 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 522 Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844 K R+E+ QR R +E ++ + R F + D + WV + L K LG +K Sbjct: 523 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 570 >gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sapiens] Length = 558 Score = 89.7 bits (221), Expect = 1e-17 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%) Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462 S + S EF+DA E S SS + I S S ++L + + L++ Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168 Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522 D R ++ + + + +G DL+KV +P + E + L+ Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228 Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579 + + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286 Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616 + E F +EQVSHHPPISA +AE ++ F + Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346 Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676 K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 404 Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734 + F ++ H I +F K+ + G+W+ +Y + V+ Sbjct: 405 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 464 Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792 + P+ K + + NE + S+SL D F L+ +++ A Sbjct: 465 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 509 Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844 K R+E+ QR R +E ++ + R F + D + WV + L K LG +K Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 557 >gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sapiens] Length = 558 Score = 89.7 bits (221), Expect = 1e-17 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%) Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462 S + S EF+DA E S SS + I S S ++L + + L++ Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168 Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522 D R ++ + + + +G DL+KV +P + E + L+ Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228 Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579 + + +L + P +RMV V + +SA+ + R GS KP+NP+LGE ++C Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286 Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616 + E F +EQVSHHPPISA +AE ++ F + Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346 Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676 K+KF G S+ + IG V+ + +H+ +IL+ W+E GE I N Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 404 Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734 + F ++ H I +F K+ + G+W+ +Y + V+ Sbjct: 405 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 464 Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792 + P+ K + + NE + S+SL D F L+ +++ A Sbjct: 465 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 509 Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844 K R+E+ QR R +E ++ + R F + D + WV + L K LG +K Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 557 >gi|19923592 oxysterol binding protein-like 11 [Homo sapiens] Length = 747 Score = 75.5 bits (184), Expect = 2e-13 Identities = 76/371 (20%), Positives = 148/371 (39%), Gaps = 60/371 (16%) Query: 500 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 559 +G DL++V +P + E + L+ + + + +L + +RM+ + ++++ Sbjct: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438 Query: 560 SYYRA-GSKPFNPVLGETYECI------------------------------------RE 582 A KP+NP++GET+ C + Sbjct: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498 Query: 583 DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 640 +F +EQVSHHPP+S +AE R V K+KF G S+ + +G ++L Sbjct: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558 Query: 641 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 700 G+ + ++ + +IL+ W+E G++ + N + F ++ H + Sbjct: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616 Query: 701 GTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEM 759 V + + V R+ G+W+ + G +Y T+ A+ + Sbjct: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663 Query: 760 DPSSKSLLPPTDTR--FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPR 817 P K P ++R ++ L E +++A K +E+ QR R E + + Sbjct: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721 Query: 818 FFRKSDDDSWV 828 +F K + D WV Sbjct: 722 YFIK-EGDGWV 731 >gi|217416392 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 [Homo sapiens] Length = 1493 Score = 57.4 bits (137), Expect = 6e-08 Identities = 37/113 (32%), Positives = 61/113 (53%), Gaps = 4/113 (3%) Query: 46 NYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSV 105 N EP + G+LLK +K W +R+F L G L Y KS +D+ R K G I++ S Sbjct: 698 NGKNEPLEKSGYLLKM-SGKVKSWKRRWFVLKGGELLYYKSPSDVIR-KPQGHIELSASC 755 Query: 106 MSVKKSSK-CIDLDTEEHIYHLKVKSEEVFDEWVSKLRH-HRMYRQNEIAMFP 156 ++ +K + L TE+H Y+L S + +EW+ L++ R+ N +++ P Sbjct: 756 SILRGDNKQTVQLTTEKHTYYLTADSPNILEEWIKVLQNVLRVQAANPLSLQP 808 >gi|55741447 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 [Homo sapiens] Length = 1364 Score = 45.4 bits (106), Expect = 2e-04 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 3/90 (3%) Query: 54 QKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSS 112 + G+LLK +K W +R+F L +G + Y KS +D+ R K G +D+ V+ + S Sbjct: 581 KSGYLLKMGS-QVKTWKRRWFVLRQGQIMYYKSPSDVIR-KPQGQVDLNSRCQIVRGEGS 638 Query: 113 KCIDLDTEEHIYHLKVKSEEVFDEWVSKLR 142 + L +E+ Y+L S + +EW+ L+ Sbjct: 639 QTFQLISEKKTYYLTADSPSLLEEWIRVLQ 668 >gi|46094081 development and differentiation enhancing factor 1 [Homo sapiens] Length = 1129 Score = 44.3 bits (103), Expect = 5e-04 Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%) Query: 4 DEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRK 63 ++K L + L+ S Q SRQ + + + L+G Y E +KG+LLKK Sbjct: 282 EKKQLTALRDLIKSSLQLDQKEDSQ-SRQGGYSMHQ-LQGNKEYGSE---KKGYLLKKSD 336 Query: 64 WPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVK---KSSKCIDLDTE 120 K W +R + GIL + + ++ + KL+ L VK + K DL + Sbjct: 337 GIRKVWQRRKCSVKNGILTISHATSNRQPAKLN------LLTCQVKPNAEDKKSFDLISH 390 Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHR 145 YH + + E+ + W+S L + + Sbjct: 391 NRTYHFQAEDEQDYVAWISVLTNSK 415 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.131 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,438,493 Number of Sequences: 37866 Number of extensions: 1537136 Number of successful extensions: 5870 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 102 Number of HSP's that attempted gapping in prelim test: 5585 Number of HSP's gapped (non-prelim): 293 length of query: 851 length of database: 18,247,518 effective HSP length: 111 effective length of query: 740 effective length of database: 14,044,392 effective search space: 10392850080 effective search space used: 10392850080 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.