Guide to the Human Genome
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Search of human proteins with 21735582

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21735582 oxysterol-binding protein-like protein 3 isoform c
[Homo sapiens]
         (851 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...  1737   0.0  
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [...  1719   0.0  
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...  1657   0.0  
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...  1639   0.0  
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...  1011   0.0  
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...   997   0.0  
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]   802   0.0  
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...   296   5e-80
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...   293   4e-79
gi|4505531 oxysterol binding protein [Homo sapiens]                   293   5e-79
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa...   291   1e-78
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...   289   9e-78
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]      266   5e-71
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [...   106   8e-23
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ...   106   8e-23
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [...   106   8e-23
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...    91   3e-18
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...    91   3e-18
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...    91   3e-18
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...    90   1e-17
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...    90   1e-17
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...    90   1e-17
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...    90   1e-17
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap...    90   1e-17
gi|22547167 oxysterol binding protein-like 9 isoform a [Homo sap...    90   1e-17
gi|22547165 oxysterol binding protein-like 9 isoform a [Homo sap...    90   1e-17
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]           75   2e-13
gi|217416392 pleckstrin homology domain containing, family H (wi...    57   6e-08
gi|55741447 pleckstrin homology domain containing, family H (wit...    45   2e-04
gi|46094081 development and differentiation enhancing factor 1 [...    44   5e-04

>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score = 1737 bits (4498), Expect = 0.0
 Identities = 851/851 (100%), Positives = 851/851 (100%)

Query: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
           MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60

Query: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
           KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
           EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180

Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
           SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240

Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
           QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300

Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
           LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360

Query: 361 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 420
           LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE
Sbjct: 361 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 420

Query: 421 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 480
           VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL
Sbjct: 421 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 480

Query: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540
           PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP
Sbjct: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540

Query: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600
           SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS
Sbjct: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600

Query: 601 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 660
           ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG
Sbjct: 601 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 660

Query: 661 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 720
           QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE
Sbjct: 661 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 720

Query: 721 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 780
           SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF
Sbjct: 721 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 780

Query: 781 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 840
           LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL
Sbjct: 781 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 840

Query: 841 GFSKLDHPVLW 851
           GFSKLDHPVLW
Sbjct: 841 GFSKLDHPVLW 851


>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
           [Homo sapiens]
          Length = 887

 Score = 1719 bits (4451), Expect = 0.0
 Identities = 851/887 (95%), Positives = 851/887 (95%), Gaps = 36/887 (4%)

Query: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
           MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60

Query: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
           KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
           EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180

Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
           SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240

Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
           QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300

Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
           LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360

Query: 361 LKQLMEQDASSSPSAQVIGLKNALSS---------------------------------- 386
           LKQLMEQDASSSPSAQVIGLKNALSS                                  
Sbjct: 361 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 420

Query: 387 --ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 444
             ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
Sbjct: 421 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 480

Query: 445 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 504
           NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
Sbjct: 481 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 540

Query: 505 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 564
           SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
Sbjct: 541 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 600

Query: 565 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 624
           GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
Sbjct: 601 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 660

Query: 625 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 684
           SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
Sbjct: 661 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 720

Query: 685 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 744
           NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
Sbjct: 721 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 780

Query: 745 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 804
           QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
Sbjct: 781 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 840

Query: 805 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 851
           RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
Sbjct: 841 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 887


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score = 1657 bits (4292), Expect = 0.0
 Identities = 820/851 (96%), Positives = 820/851 (96%), Gaps = 31/851 (3%)

Query: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
           MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60

Query: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
           KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
           EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180

Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
           SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240

Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
           QSMDVLHRTYSAPAINAIQ                               VPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR 269

Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
           LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 270 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 329

Query: 361 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 420
           LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE
Sbjct: 330 LKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQE 389

Query: 421 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 480
           VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL
Sbjct: 390 VLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCL 449

Query: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540
           PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP
Sbjct: 450 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 509

Query: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600
           SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS
Sbjct: 510 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 569

Query: 601 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 660
           ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG
Sbjct: 570 ACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSG 629

Query: 661 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 720
           QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE
Sbjct: 630 QRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHE 689

Query: 721 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 780
           SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF
Sbjct: 690 SIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRF 749

Query: 781 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 840
           LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL
Sbjct: 750 LEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDL 809

Query: 841 GFSKLDHPVLW 851
           GFSKLDHPVLW
Sbjct: 810 GFSKLDHPVLW 820


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score = 1639 bits (4245), Expect = 0.0
 Identities = 820/887 (92%), Positives = 820/887 (92%), Gaps = 67/887 (7%)

Query: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60
           MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK
Sbjct: 1   MMSDEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLK 60

Query: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120
           KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE
Sbjct: 61  KRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTE 120

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180
           EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS
Sbjct: 121 EHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSIS 180

Query: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240
           SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL
Sbjct: 181 SRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLL 240

Query: 241 QSMDVLHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVR 300
           QSMDVLHRTYSAPAINAIQ                               VPKPFSGPVR
Sbjct: 241 QSMDVLHRTYSAPAINAIQ-------------------------------VPKPFSGPVR 269

Query: 301 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 360
           LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK
Sbjct: 270 LHSSNPNLSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREK 329

Query: 361 LKQLMEQDASSSPSAQVIGLKNALSS---------------------------------- 386
           LKQLMEQDASSSPSAQVIGLKNALSS                                  
Sbjct: 330 LKQLMEQDASSSPSAQVIGLKNALSSALAQNTDLKERLRRIHAESLLLDSPAVAKSGDNL 389

Query: 387 --ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 444
             ENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD
Sbjct: 390 AEENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISD 449

Query: 445 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 504
           NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL
Sbjct: 450 NLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDL 509

Query: 505 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 564
           SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA
Sbjct: 510 SKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRA 569

Query: 565 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 624
           GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK
Sbjct: 570 GSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGK 629

Query: 625 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 684
           SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV
Sbjct: 630 SMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKV 689

Query: 685 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 744
           NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE
Sbjct: 690 NFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYE 749

Query: 745 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 804
           QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR
Sbjct: 750 QYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERR 809

Query: 805 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 851
           RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW
Sbjct: 810 RVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSKLDHPVLW 856


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score = 1011 bits (2613), Expect = 0.0
 Identities = 515/935 (55%), Positives = 661/935 (70%), Gaps = 85/935 (9%)

Query: 1   MMSDEKNLGVSQKLVSPSR--STSSCSSKQGSRQ-------------------------- 32
           M SDEK +  + K  +P+   ++SS SS++ SRQ                          
Sbjct: 1   MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEP 60

Query: 33  -------DSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAK 85
                  DSWE++EGL+      Q+P   +GF+LKKRKWPLKGWHKRFF LD G+LKY+K
Sbjct: 61  VPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSK 120

Query: 86  SQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145
           +  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVKS++ FD WVSKLRHHR
Sbjct: 121 APLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHR 180

Query: 146 MYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SSISKQNLFQTGSNVSFS 202
           +YRQNEI   P + + H F  ++  +SS     S+   K   +S   Q+     +++  +
Sbjct: 181 LYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPAT 240

Query: 203 CG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHRTYSAPAINAIQGG 261
           C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++L RT SAP    +Q  
Sbjct: 241 CTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQAN 300

Query: 262 SFESPKKEKRSHRRWRSRAIGKDAKGTLQVP-KPFSGPVRLHSSNPNL-STLDFGEEKNY 319
             +  KK+KR  RRWR++++ KD K  LQVP      PVRLHSSNPNL + ++F    ++
Sbjct: 301 CVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSH 360

Query: 320 -SDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQV 377
            +D  E+S++++K+QE+ C IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+
Sbjct: 361 LTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQM 420

Query: 378 IGLKNALS-----------------SEN-------------SRDENRALVH-------QL 400
             L+ +LS                 SE+             S DE    +H       Q+
Sbjct: 421 ARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQV 480

Query: 401 SNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQ 460
           +NESRLS+++S+SEFFDAQEVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ
Sbjct: 481 ANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQ 540

Query: 461 TLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTL 520
            L   L  G   ++ RR CLPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTL
Sbjct: 541 ILNGELTGGA-FRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTL 599

Query: 521 QRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECI 580
           Q LCEE+EYSELLDKA++   P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECI
Sbjct: 600 QHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECI 659

Query: 581 REDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 640
           REDKGF+FFSEQVSHHPPISACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP 
Sbjct: 660 REDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPK 719

Query: 641 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 700
           +GD++ WNKVT+CIHNILSG+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++
Sbjct: 720 YGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQ 779

Query: 701 GTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMD 760
           G V D+ GKAV+RLFGKWHE +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+D
Sbjct: 780 GVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELD 839

Query: 761 PSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFR 820
           P  K LLPPTD RFRPDQRFLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+
Sbjct: 840 PVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFK 899

Query: 821 KSDD----DSWVSNGTYLELRKDLGFSKLDHPVLW 851
           K  D    ++WVSN TY ELRKD GFSK+D PVLW
Sbjct: 900 KVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW 934


>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score =  997 bits (2577), Expect = 0.0
 Identities = 506/916 (55%), Positives = 647/916 (70%), Gaps = 81/916 (8%)

Query: 10  VSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGW 69
           VS++L+ P     S         DSWE++EGL+      Q+P   +GF+LKKRKWPLKGW
Sbjct: 30  VSRQLLEPEPVPLS------KEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGW 83

Query: 70  HKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVK 129
           HKRFF LD G+LKY+K+  DI++ K+HG IDVGLSVMS+KK ++ IDLDTEEHIYHLKVK
Sbjct: 84  HKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVK 143

Query: 130 SEEVFDEWVSKLRHHRMYRQNEIAMFPHEVN-HFFSGSTITDSSSGVFDSISSRKR--SS 186
           S++ FD WVSKLRHHR+YRQNEI   P + + H F  ++  +SS     S+   K   +S
Sbjct: 144 SQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNS 203

Query: 187 ISKQNLFQTGSNVSFSCG-GETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDV 245
              Q+     +++  +C  G+++V  WLQ SE+M++C++DLAHC + LVE+S+LLQ++++
Sbjct: 204 FPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEI 263

Query: 246 LHRTYSAPAINAIQGGSFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSG-------- 297
           L RT SAP    +Q    +  KK+KR  RRWR++++ KD K  LQ   P  G        
Sbjct: 264 LQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFSTTRRR 323

Query: 298 ------------------PVRLHSSNPNL-STLDFGEEKNY-SDGSETSSEFSKMQEDLC 337
                             PVRLHSSNPNL + ++F    ++ +D  E+S++++K+QE+ C
Sbjct: 324 QRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFC 383

Query: 338 HIAHKVYFTLRSAFNIMSAEREKLKQLM-EQDASSSPSAQVIGLKNALS----------- 385
            IA KV+  L+SAFN ++ E+EKLKQ++ EQD S   S Q+  L+ +LS           
Sbjct: 384 LIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRS 443

Query: 386 ------SEN-------------SRDENRALVH-------QLSNESRLSITDSLSEFFDAQ 419
                 SE+             S DE    +H       Q++NESRLS+++S+SEFFDAQ
Sbjct: 444 RLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQ 503

Query: 420 EVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTC 479
           EVLLS SSSENE SDD+SY+SD+SDN+S DN S   +  RQ L   L  G   ++ RR C
Sbjct: 504 EVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGA-FRNGRRAC 562

Query: 480 LPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQI 539
           LPAPCP +SNI+LWNILRNNIGKDLSKV+MPVELNEPLNTLQ LCEE+EYSELLDKA++ 
Sbjct: 563 LPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASET 622

Query: 540 PSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPI 599
             P ERMV VAAFA+S Y S+Y+RAGSKPFNPVLGETYECIREDKGF+FFSEQVSHHPPI
Sbjct: 623 DDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPI 682

Query: 600 SACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILS 659
           SACH ES+NFVFWQD+RWKNKFWGKSMEI+P+GT +V LP +GD++ WNKVT+CIHNILS
Sbjct: 683 SACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILS 742

Query: 660 GQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWH 719
           G+RWIEHYGE+ I+N     C CK+ F+K  YW++N +E++G V D+ GKAV+RLFGKWH
Sbjct: 743 GRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWH 802

Query: 720 ESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQR 779
           E +YCG   S+ C+WR   MP  YE YY FT+FA+ELNE+DP  K LLPPTD RFRPDQR
Sbjct: 803 EGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQR 862

Query: 780 FLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD----DSWVSNGTYLE 835
           FLEEGNLE A  +KQR+E+LQR RRR +EEN++EH P+FF+K  D    ++WVSN TY E
Sbjct: 863 FLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWE 922

Query: 836 LRKDLGFSKLDHPVLW 851
           LRKD GFSK+D PVLW
Sbjct: 923 LRKDPGFSKVDSPVLW 938


>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
          Length = 842

 Score =  802 bits (2072), Expect = 0.0
 Identities = 430/870 (49%), Positives = 552/870 (63%), Gaps = 74/870 (8%)

Query: 17  PSRSTSSCSSKQGSRQDSWEVVE------GLRGEMNYTQEPPVQKGFLLKKRKWPLKGWH 70
           P  + SS  S      + WEVVE      G  G M     P  Q+G LLKKRKWPLKGWH
Sbjct: 12  PESAQSSKPSSAQQASELWEVVEEPRVRLGTEGVM-----PERQEGHLLKKRKWPLKGWH 66

Query: 71  KRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSKCIDLDTEEHIYHLKVKS 130
           KR+F L+ GIL YA ++ DI + KLHG IDV LSVMS+ K ++ IDLDTE++IYHLK+KS
Sbjct: 67  KRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKS 126

Query: 131 EEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISSRKRSSISKQ 190
           +++F  WV++LR HR+  +                    D   G   S + RK       
Sbjct: 127 QDLFQSWVAQLRAHRLAHR-------------------LDMPRGSLPSTAHRKVPGAQ-- 165

Query: 191 NLFQTGSNVSF--SCGGETRVPLWLQSSEDMEKCSKDLAHCHAYLVEMSQLLQSMDVLHR 248
               T +  S     G   +V  WL+ S+ +++CS +L+ C   L E+ +LLQS++ LHR
Sbjct: 166 --LPTAATASALPGLGPREKVSSWLRDSDGLDRCSHELSECQGKLQELHRLLQSLESLHR 223

Query: 249 TYSAPAINAIQGG-SFESPKKEKRSHRRWRSRAIGKDAKGTLQVPKPFSGPVRLHSSNPN 307
             SAP I   Q   + E PKK KR+ R W +++  KD               RLH S PN
Sbjct: 224 IPSAPVIPTHQASVTTERPKKGKRTSRMWCTQSFAKD--------DTIGRVGRLHGSVPN 275

Query: 308 LSTLDFGEEKNYSDGSETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLK----- 362
           LS      + + + G   + +++ +Q     +A KV+ +L S    ++ ER++L+     
Sbjct: 276 LSRYLESRDSSGTRGLPPT-DYAHLQRSFWALAQKVHSSLSSVLAALTMERDQLRDMHQG 334

Query: 363 ----------------QLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRL 406
                           +L     SS  +A      N    E    + R L  QLS  S L
Sbjct: 335 SELSRMGVSEASTGQRRLHSLSTSSDTTADSFSSLNPEEQEALYMKGRELTPQLSQTSIL 394

Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDD-SYVSDISDNLSLDNLSNDLDNERQTLGPV 465
           S+ DS +EFFDA EVLLS SSSENE S+++ S  S+I+ +LS + L  DL    +     
Sbjct: 395 SLADSHTEFFDACEVLLSASSSENEGSEEEESCTSEITTSLSEEML--DLRGAERCQKGG 452

Query: 466 LDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCE 525
              GR     RR CLPA     +++SLWNILRNNIGKDLSKV+MPV+LNEPLNTLQRLCE
Sbjct: 453 CVPGRPMGPPRRRCLPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCE 512

Query: 526 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKG 585
           ELEYS LLD+A++I  P ERMVY+AAFA+SAY+S+Y+RAG KPFNPVLGETYEC R D+G
Sbjct: 513 ELEYSSLLDQASRIADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRG 572

Query: 586 FQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHF 645
           F+F SEQVSHHPPISACHAES NF FWQD++WKNKFWGKS+EIVP+GT +V+LP FGDHF
Sbjct: 573 FRFISEQVSHHPPISACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHF 632

Query: 646 EWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFD 705
           EWNKVTSCIHN+LSGQRWIEHYGE++I+N  D SC+CK+ F KAKYWS+N HE++G V  
Sbjct: 633 EWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLS 692

Query: 706 RSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKS 765
           RSG+ +HRLFGKWHE +Y G      C+W+ N MP  +E+ + FTQFALELNE+    K 
Sbjct: 693 RSGRVLHRLFGKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKR 752

Query: 766 LLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDDD 825
            LP TDTR RPDQR+LEEGN++ AE QK+RIEQLQR+RR+V+EEN++ HQ RFFR+  D 
Sbjct: 753 SLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDS 812

Query: 826 S----WVSNGTYLELRKDLGFSKLDHPVLW 851
           S    WV+N TY  LR + G+  +D  VLW
Sbjct: 813 SGKEWWVTNNTYWRLRAEPGYGNMDGAVLW 842


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score =  296 bits (758), Expect = 5e-80
 Identities = 182/523 (34%), Positives = 271/523 (51%), Gaps = 79/523 (15%)

Query: 379 GLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSY 438
           G++N    E  +++N+ L   L   +        +E  + ++ L+  S   + +S+D+ Y
Sbjct: 427 GVRN-FKLEQEQEKNKILSEALETLA--------TEHHELEQSLVKGSPPASILSEDEFY 477

Query: 439 --VSDISDNLSLDNL----SNDLDNERQTLGPVLDSGREAKS------------RRRTCL 480
             +SD     SL  L    +   + E + LG       E K             + RT L
Sbjct: 478 DALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSL 537

Query: 481 PAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIP 540
           P+P  S ++ S+W+ILR  IG +LSK+ MPV  NEPL+ LQRL E +E++ L+ KA+ + 
Sbjct: 538 PSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLS 597

Query: 541 SPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVSHHPPIS 600
            P+ERM  VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+  SEQVSHHPPIS
Sbjct: 598 DPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVSHHPPIS 656

Query: 601 ACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNIL 658
           A HAE  N  F+F   +  K KFWGKS+E  P GT  + L    + + W   T C+HNI+
Sbjct: 657 AFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNII 716

Query: 659 SGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKW 718
            G+ WIE YG + I N H     C +NF     +    H++EG + D+S K +  L+GKW
Sbjct: 717 VGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKW 775

Query: 719 HESIYCGGGSS-------------------------------------------SACVWR 735
            E +Y    ++                                           S  +WR
Sbjct: 776 TECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWR 835

Query: 736 ANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQR 795
             P P    Q Y+FT FA+ LNE+D   +S++P TD R RPD R +E G +++A  +K+R
Sbjct: 836 IAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKR 895

Query: 796 IEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 833
           +E+ QR  R+   ++  + + R+F +  +       W+ +G+Y
Sbjct: 896 LEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 938



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 17/133 (12%)

Query: 68  GWHKRFFYLDKGILKYAKSQTD-IEREKLHGCIDVGLSVMSVKKSSKCI----DLDTEEH 122
           GW   +  L+ G+L + + Q D +      GC  +  +V +VK +  C+      D   H
Sbjct: 250 GWRLFWVVLEHGVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTDSCLFFIKCFDDTIH 309

Query: 123 IYHLKVKS-EEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSSSGVFDSISS 181
            + +   S ++  ++W+  +  H  Y             H+ S   +TD       S + 
Sbjct: 310 GFRVPKNSLQQSREDWLEAIEEHSAYS-----------THYCSQDQLTDEEEEDTVSAAD 358

Query: 182 RKRSSISKQNLFQ 194
            K+S    Q+  Q
Sbjct: 359 LKKSLEKAQSCQQ 371


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score =  293 bits (751), Expect = 4e-79
 Identities = 180/475 (37%), Positives = 251/475 (52%), Gaps = 63/475 (13%)

Query: 414 EFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREAK 473
           EFFDA     S +SS  E S+ +  V+ + D  +  N       ER    P  ++G +  
Sbjct: 6   EFFDAVTGFDSDNSS-GEFSEANQKVTGMIDLDTSKNNRIGKTGER----PSQENGIQ-- 58

Query: 474 SRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELL 533
            + RT LPAP  S S+ S+W IL+  +G +LSK+ MP+  NEPL+ LQR+ E +E+  L+
Sbjct: 59  -KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLI 117

Query: 534 DKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQV 593
            +A+  P PLERM  VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQV
Sbjct: 118 HRASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQV 176

Query: 594 SHHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVT 651
           SHHPPISA H+E  N  F+F   +  K KFWGKS+E  P GT  + L    + + W   T
Sbjct: 177 SHHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPT 236

Query: 652 SCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAV 711
            C+HN++ G+ WIE YG + I N H     C ++F     +    H++EG + D++ K +
Sbjct: 237 CCVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKL 295

Query: 712 HRLFGKWHESIY----------------------------CGGGSS-------------- 729
             ++GKW E ++                             G   S              
Sbjct: 296 FMIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQ 355

Query: 730 ----SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGN 785
               S  +WR N  P    Q Y+FT F + LNE++   +  LPPTD R RPD R +E GN
Sbjct: 356 VIPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGN 415

Query: 786 LEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 835
           ++ A  +K+R+E+ QRE RR   +   E Q R+F   ++       W+  G Y E
Sbjct: 416 MDLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 470


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score =  293 bits (750), Expect = 5e-79
 Identities = 171/430 (39%), Positives = 251/430 (58%), Gaps = 45/430 (10%)

Query: 401 SNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQ 460
           S +  +S  D  +EFFDA E++  P +  ++ +   S +S  S ++SLD      +  + 
Sbjct: 345 SGKGDMSDEDDENEFFDAPEIITMPENLGHKRTG--SNISGASSDISLD------EQYKH 396

Query: 461 TLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTL 520
            L        E K  +RT +P     + +++LW+I++N IGK+LSK+ MPV  NEPL+ L
Sbjct: 397 QL-------EETKKEKRTRIPYK--PNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSML 447

Query: 521 QRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECI 580
           QRL E+LEY ELLD+AA+  + LE++ YVAAF +S+Y+++ +R  SKPFNP+LGET+E  
Sbjct: 448 QRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRT-SKPFNPLLGETFELD 506

Query: 581 R-EDKGFQFFSEQVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTL 638
           R E+ G++   EQVSHHPP +A HAES+N +   Q+++  +KF GK + I+P+GT H   
Sbjct: 507 RLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIF 566

Query: 639 PVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AH 697
              G H+ W KVT+ +HNI+ G+ WI+  GEI I N H     C + F+   Y+S + A 
Sbjct: 567 HATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVN-HKTGDKCNLKFVPYSYFSRDVAR 625

Query: 698 EIEGTVFDRSGKAVHRLFGKWHESIYC---------GGG----------SSSACVWRANP 738
           ++ G V D SGK    L G W E + C          GG           S   +W+ NP
Sbjct: 626 KVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQRGHEAEESRVMLWKRNP 685

Query: 739 MPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQ 798
           +PK  E  Y F++ AL LN  +  +     PTD+R RPDQR +E G  +EA  +KQR+E+
Sbjct: 686 LPKNAENMYYFSELALTLNAWESGT----APTDSRLRPDQRLMENGRWDEANAEKQRLEE 741

Query: 799 LQRERRRVLE 808
            QR  R+  E
Sbjct: 742 KQRLSRKKRE 751



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 2/88 (2%)

Query: 54  QKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSSK 113
           ++G+L K   + +KG+ +R+F L  G+L Y +S+ ++ R    G I++  + ++V+ S  
Sbjct: 91  REGWLFKWTNY-IKGYQRRWFVLSNGLLSYYRSKAEM-RHTCRGTINLATANITVEDSCN 148

Query: 114 CIDLDTEEHIYHLKVKSEEVFDEWVSKL 141
            I  +     YHLK  SE     WV+ L
Sbjct: 149 FIISNGGAQTYHLKASSEVERQRWVTAL 176


>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
           sapiens]
          Length = 437

 Score =  291 bits (746), Expect = 1e-78
 Identities = 160/409 (39%), Positives = 229/409 (55%), Gaps = 52/409 (12%)

Query: 475 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 534
           + RT LP+P  S ++ S+W+ILR  IG +LSK+ MPV  NEPL+ LQRL E +E++ L+ 
Sbjct: 19  KHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIH 78

Query: 535 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 594
           KA+ +  P+ERM  VAAFA+SA AS + R G KPFNP+LGETYE +R+D GF+  SEQVS
Sbjct: 79  KASSLSDPVERMQCVAAFAVSAVASQWERTG-KPFNPLLGETYELVRDDLGFRLISEQVS 137

Query: 595 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 652
           HHPPISA HAE  N  F+F   +  K KFWGKS+E  P GT  + L    + + W   T 
Sbjct: 138 HHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTC 197

Query: 653 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 712
           C+HNI+ G+ WIE YG + I N H     C +NF     +    H++EG + D+S K + 
Sbjct: 198 CVHNIIVGKLWIEQYGNVEIIN-HKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLC 256

Query: 713 RLFGKWHESIYCGGGSS------------------------------------------- 729
            L+GKW E +Y    ++                                           
Sbjct: 257 ALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPG 316

Query: 730 SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEA 789
           S  +WR  P P    Q Y+FT FA+ LNE+D   +S++P TD R RPD R +E G +++A
Sbjct: 317 SVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQA 376

Query: 790 EIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTY 833
             +K+R+E+ QR  R+   ++  + + R+F +  +       W+ +G+Y
Sbjct: 377 SEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYSGSY 425


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score =  289 bits (739), Expect = 9e-78
 Identities = 163/414 (39%), Positives = 225/414 (54%), Gaps = 55/414 (13%)

Query: 475 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 534
           + RT LPAP  S S+ S+W IL+  +G +LSK+ MP+  NEPL+ LQR+ E +E+  L+ 
Sbjct: 47  KHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 106

Query: 535 KAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIREDKGFQFFSEQVS 594
           +A+  P PLERM  VAAFA+SA AS + R G KPFNP+LGETYE IRED GF+F SEQVS
Sbjct: 107 RASCQPQPLERMQSVAAFAVSAVASQWERTG-KPFNPLLGETYELIREDLGFRFISEQVS 165

Query: 595 HHPPISACHAESRN--FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTS 652
           HHPPISA H+E  N  F+F   +  K KFWGKS+E  P GT  + L    + + W   T 
Sbjct: 166 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 225

Query: 653 CIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIEGTVFDRSGKAVH 712
           C+HN++ G+ WIE YG + I N H     C ++F     +    H++EG + D++ K + 
Sbjct: 226 CVHNVIIGKLWIEQYGTVEILN-HRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLF 284

Query: 713 RLFGKWHESIY----------------------------CGGGSS--------------- 729
            ++GKW E ++                             G   S               
Sbjct: 285 MIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQV 344

Query: 730 ---SACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNL 786
              S  +WR N  P    Q Y+FT F + LNE++   +  LPPTD R RPD R +E GN+
Sbjct: 345 IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNM 404

Query: 787 EEAEIQKQRIEQLQRERRRVLEENHVEHQPRFFRKSDD-----DSWVSNGTYLE 835
           + A  +K+R+E+ QRE RR   +   E Q R+F   ++       W+  G Y E
Sbjct: 405 DLASQEKERLEEKQREARRERAKEEAEWQTRWFYPGNNPYTGTPDWLYAGDYFE 458


>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score =  266 bits (681), Expect = 5e-71
 Identities = 173/480 (36%), Positives = 264/480 (55%), Gaps = 45/480 (9%)

Query: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDEN--RALVHQ--LSNESRLSITDSL 412
           +R  L++ +EQ A    S     L+ A  S   R  N  ++ +    L+ +   S  D  
Sbjct: 395 QRVHLEETIEQLAKQHNS-----LERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDED 449

Query: 413 SEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREA 472
           +E+FDA E   S  +   E  +D       +   S+D  S D   +  +L P   S    
Sbjct: 450 TEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSS---- 505

Query: 473 KSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSEL 532
           K +RR  +P     + +++LW+I++N IG++LS++ MPV  NEPL+ LQRL E+LEY  L
Sbjct: 506 KVKRRVRIPNK--PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHL 563

Query: 533 LDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIR-EDKGFQFFSE 591
           LDKA    S +E+M  VAAF++S+Y+++ +R  +KPFNP+LGET+E  R +D G +   E
Sbjct: 564 LDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDMGLRSLCE 622

Query: 592 QVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKV 650
           QVSHHPP +A +  S++ +  WQ++   +KF GK + I+P+G  H+     G+H+ W K 
Sbjct: 623 QVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKS 682

Query: 651 TSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AHEIEGTVFDRSGK 709
           TS +HNI+ G+ WI+  G+I I N H  +  C++ F+   Y+S   A ++ G V D  GK
Sbjct: 683 TSTVHNIIVGKLWIDQSGDIEIVN-HKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGK 741

Query: 710 AVHRLFGKWHESIYCG--------------------GGSSSACVWRANPMPKGYEQYYSF 749
           A + L G W E + C                        S+  +W+  P+P+  E  Y F
Sbjct: 742 AHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYF 801

Query: 750 TQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR-ERRRVLE 808
           ++ AL LNE +      + PTD+R RPDQR +E+G  +EA  +KQR+E+ QR  RRR LE
Sbjct: 802 SELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLE 857



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 55  KGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCI-DVGLSVMSVKKSSK 113
           +G+LLK   + LKG+ +R+F L  G+L Y ++Q     E  H C   + LS   +     
Sbjct: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQ----GEMAHTCRGTINLSTAHIDTEDS 240

Query: 114 C-IDLDTEEHIYHLKVKSEEVFDEWVSKL 141
           C I L +    YHLK  SE    +W++ L
Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITAL 269


>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
           [Homo sapiens]
          Length = 879

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 486 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 543
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 364 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 423

Query: 544 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 596
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 424 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 479

Query: 597 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 654
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 480 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 539

Query: 655 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 711
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 540 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 596

Query: 712 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 769
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 597 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 650

Query: 770 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 819
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 651 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 696


>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 486 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 543
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355

Query: 544 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 596
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411

Query: 597 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 654
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471

Query: 655 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 711
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528

Query: 712 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 769
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582

Query: 770 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 819
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628


>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  106 bits (265), Expect = 8e-23
 Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 33/350 (9%)

Query: 486 SSSNISL-WNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPL 543
           S  N SL W +L+    G DLS+V +P  + EP + L +L +   +++LL +AA      
Sbjct: 296 SEENKSLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAY 355

Query: 544 ERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYECI----REDKGFQFFSEQVSHH 596
            RM  V  +    Y S +Y+      KP+NP+LGET+ C     + D    + +EQVSHH
Sbjct: 356 SRMKLVLRW----YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHH 411

Query: 597 PPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCI 654
           PP+SA H  +R   F     +  K++F+G S+  +  G   +T     + +      +  
Sbjct: 412 PPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHC 471

Query: 655 HNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYW--STNAHEIEGTVFDRSGKAV- 711
             IL G   +E  G++ I+    ++   ++ F    ++  ST+ ++I G +   SG+ V 
Sbjct: 472 KGILYGTMTLELGGKVTIE-CAKNNFQAQLEFKLKPFFGGSTSINQISGKI--TSGEEVL 528

Query: 712 HRLFGKWHESIYC--GGGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPP 769
             L G W   ++    G  SSA  W     P G  +     Q  + L E        L  
Sbjct: 529 ASLSGHWDRDVFIKEEGSGSSALFW----TPSGEVRRQRLRQHTVPLEEQTELESERL-- 582

Query: 770 TDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPRFF 819
               ++   R + +G+   A  +K  +E+ QR+R R  +E+ +  +P+ F
Sbjct: 583 ----WQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMPWKPQLF 628


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 84/336 (25%), Positives = 148/336 (44%), Gaps = 33/336 (9%)

Query: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 416
           +R  +++  E D S S  +  +     L + N        +H   N  +L+ ++   + F
Sbjct: 229 KRTMIREGKEHDLSVSSDSTHVTFYGLLRANN--------LHSGDN-FQLNDSEIERQHF 279

Query: 417 DAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSGREA 472
             Q++    S  EN+   D  D+ V   S+    D      D+  E + + P+ ++    
Sbjct: 280 KDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTE 339

Query: 473 KSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCE 525
           +S            +  +S      +W +L+    G DLSKV +P  + EP + L +L +
Sbjct: 340 QSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSD 399

Query: 526 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYECI-- 580
              +++ L +AA   +P  R+  V    +  Y S +Y+      KP+NP+LGET+ C+  
Sbjct: 400 YYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRCLWI 455

Query: 581 --REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHV 636
             R +    + +EQVSHHPPISA +  +R   F     +  K+KF+G S+  +  G   +
Sbjct: 456 HPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARL 515

Query: 637 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 672
           T    G+ +      +    IL G   +E  G + I
Sbjct: 516 TFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 551


>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 84/336 (25%), Positives = 148/336 (44%), Gaps = 33/336 (9%)

Query: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 416
           +R  +++  E D S S  +  +     L + N        +H   N  +L+ ++   + F
Sbjct: 271 KRTMIREGKEHDLSVSSDSTHVTFYGLLRANN--------LHSGDN-FQLNDSEIERQHF 321

Query: 417 DAQEVLLSPSSSENEISDD--DSYVSDISDNLSLDNLSNDLDN--ERQTLGPVLDSGREA 472
             Q++    S  EN+   D  D+ V   S+    D      D+  E + + P+ ++    
Sbjct: 322 KDQDMYSDKSDKENDQEHDESDNEVMGKSEESDTDTSERQDDSYIEPEPVEPLKETTYTE 381

Query: 473 KSRRRTCLPAPCPSSSNIS------LWNILRN-NIGKDLSKVAMPVELNEPLNTLQRLCE 525
           +S            +  +S      +W +L+    G DLSKV +P  + EP + L +L +
Sbjct: 382 QSHEELGEAGEASQTETVSEENKSLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSD 441

Query: 526 ELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAG---SKPFNPVLGETYECI-- 580
              +++ L +AA   +P  R+  V    +  Y S +Y+      KP+NP+LGET+ C+  
Sbjct: 442 YYYHADFLSEAALEENPYFRLKKV----VKWYLSGFYKKPKGLKKPYNPILGETFRCLWI 497

Query: 581 --REDKGFQFFSEQVSHHPPISACHAESR--NFVFWQDVRWKNKFWGKSMEIVPIGTTHV 636
             R +    + +EQVSHHPPISA +  +R   F     +  K+KF+G S+  +  G   +
Sbjct: 498 HPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARL 557

Query: 637 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVI 672
           T    G+ +      +    IL G   +E  G + I
Sbjct: 558 TFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNI 593


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 117/568 (20%), Positives = 222/568 (39%), Gaps = 88/568 (15%)

Query: 300 RLHSSNPNLSTLDFGEEKNYSDGSET---SSEFSKMQEDLCHIAHKVYFTLRSAFNIMSA 356
           +LH     ++ ++ G++KN     E+   S   + + +DL  +      TL      ++ 
Sbjct: 237 QLHEVREMMNQVE-GQQKNLVHAIESLPGSGPLTALDQDLLLLKATSAATLSCLGECLNL 295

Query: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDENRALVHQLSNESRLSITDSLSEFF 416
            ++ + Q  +       S  ++G   + S    + +N  L    S  + ++         
Sbjct: 296 LQQSVHQAGQPSQKPGASENILGWHGSKSHSTEQLKNGTLGSLPSASANITWA------- 348

Query: 417 DAQEVLLSPSSSENEISDDDSYVSDISDNLSL--DNLSNDLDNERQTLGPVLDSGREAKS 474
                 + P+S+E+E +       +    L L  D  S++ D E   LG + D       
Sbjct: 349 ------ILPNSAEDEQTSQPEPEPNSGSELVLSEDEKSDNEDKEETELGVMEDQ------ 396

Query: 475 RRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLD 534
                         +I L  I +  +G DL+KV +P  + E  + L+   + + + +LL 
Sbjct: 397 -------------RSIILHLISQLKLGMDLTKVVLPTFILEKRSLLEMYADFMAHPDLLL 443

Query: 535 KAAQIPSPLERMVYVAAFAISAYASSYYRA-GSKPFNPVLGETYECIRE----------- 582
                 +P ER++    + ++A+      A   KP+NP++GET+ C  E           
Sbjct: 444 AITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKPKRT 503

Query: 583 -----------------DKGFQ--FFSEQVSHHPPISA--CHAESRNFVFWQDVRWKNKF 621
                             K ++  F +EQVSHHPPIS   C  E +       V  K+KF
Sbjct: 504 ASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWTKSKF 563

Query: 622 WGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCY 681
            G S+ +  IG   + L   G+ + +   ++   +IL+   W+E  G++ I N       
Sbjct: 564 MGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILT-IPWVELGGKVSI-NCAKTGYS 621

Query: 682 CKVNFIKAKYWSTNAHEIEGTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMP 740
             V F    ++    H +   V  + +   V +  G+W+ ++     +    V     +P
Sbjct: 622 ATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFTYNNGETKVIDTTTLP 681

Query: 741 KGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQ 800
                        +   ++ P  K     +   +R   R+L  G+++ A  QK+ +E+ Q
Sbjct: 682 -------------VYPKKIRPLEKQGPMESRNLWREVTRYLRLGDIDAATEQKRHLEEKQ 728

Query: 801 RERRRVLEENHVEHQPRFFRKSDDDSWV 828
           R   R  E      +P++F + + D WV
Sbjct: 729 RVEERKRENLRTPWKPKYFIQ-EGDGWV 755



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 35/156 (22%), Positives = 64/156 (41%), Gaps = 19/156 (12%)

Query: 18  SRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLD 77
           SRS ++     GSR     V     G     +EP ++   +L K    L+GW  R+F LD
Sbjct: 42  SRSAAAGLGGGGSRSSPGSVAASPSGGGGRRREPALEG--VLSKYTNLLQGWQNRYFVLD 99

Query: 78  --KGILKYAKSQTDIEREKLHGCIDVGLSVMSVKKSS--KCIDLDTEEHIYHLKVKSEEV 133
              GIL+Y  ++   + +K  G + +  +++S+   +    +       ++ L+    + 
Sbjct: 100 FEAGILQYFVNEQS-KHQKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKE 158

Query: 134 FDEWVSKLRHHRMY------------RQNEIAMFPH 157
              WV++LR    Y            R   + + PH
Sbjct: 159 KQFWVTQLRACAKYHMEMNSKSAPSSRSRSLTLLPH 194


>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 287 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 346

Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 347 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 406

Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 407 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 464

Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 465 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 524

Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 525 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 582

Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 583 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 642

Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 643 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 687

Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 688 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 735



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
             ++  +H + +  +  ++W+  L      H +  Q   + F   V  F    T  D+
Sbjct: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 297 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 356

Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 357 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 416

Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 417 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 474

Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 475 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 534

Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 535 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 592

Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 593 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 652

Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 653 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 697

Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 698 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 745



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 118 DTEEHIYHLKVKSEEVFDEWVSKL 141
             ++  +H + +  +  ++W+  L
Sbjct: 71  TVDQKTFHFQARDADEREKWIHAL 94


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 333

Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 334 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 393

Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 394 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 451

Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511

Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 512 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 569

Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 570 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 629

Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 630 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 674

Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 675 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 722



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 9/118 (7%)

Query: 63  KWP--LKGWHKRFFYLD--KGILKYAKSQTDIEREKLHGCIDVGLSVMSV-KKSSKCIDL 117
           KW   +KGW  R+F LD   G+L Y  S+  + R    GC+ +  +V+ +  +      +
Sbjct: 11  KWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDSTFTI 70

Query: 118 DTEEHIYHLKVKSEEVFDEWVSKLR----HHRMYRQNEIAMFPHEVNHFFSGSTITDS 171
             ++  +H + +  +  ++W+  L      H +  Q   + F   V  F    T  D+
Sbjct: 71  TVDQKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDFDKKLTEADA 128


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 177 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 236

Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 237 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 296

Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 297 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 354

Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 355 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 414

Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 415 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 472

Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 473 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 532

Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 533 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 577

Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 578 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 625


>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
           sapiens]
          Length = 571

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 122 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 181

Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 182 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 241

Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 242 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 299

Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 300 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 359

Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 360 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 417

Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 418 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 477

Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 478 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 522

Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 523 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 570


>gi|22547167 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168

Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228

Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286

Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346

Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 404

Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 405 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 464

Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 465 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 509

Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 557


>gi|22547165 oxysterol binding protein-like 9 isoform a [Homo
           sapiens]
          Length = 558

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 114/472 (24%), Positives = 194/472 (41%), Gaps = 57/472 (12%)

Query: 407 SITDSLSEFFDAQEVLLSPSSSENEISDDDSYV----SDISDNLSLDNLSNDLDNERQTL 462
           S + S  EF+DA E   S SS +  I    S      S   ++L   + +  L++     
Sbjct: 109 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDTTESLNSSLSNG 168

Query: 463 GPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQR 522
               D       R             ++ +  + +  +G DL+KV +P  + E  + L+ 
Sbjct: 169 TSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEM 228

Query: 523 LCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGS---KPFNPVLGETYEC 579
             +   + +L    +    P +RMV V  + +SA+ +   R GS   KP+NP+LGE ++C
Sbjct: 229 YADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAG--RKGSVAKKPYNPILGEIFQC 286

Query: 580 --------------IRED-------KGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVR 616
                         + E            F +EQVSHHPPISA +AE  ++   F   + 
Sbjct: 287 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 346

Query: 617 WKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLH 676
            K+KF G S+ +  IG   V+   + +H+          +IL+   W+E  GE  I N  
Sbjct: 347 TKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILT-VPWVELGGECNI-NCS 404

Query: 677 DDSCYCKVNFIKAKYWSTNAHEIEGTVFD-RSGKAVHRLFGKWHESIYCGGGSSSACVW- 734
                  + F    ++    H I   +F     K+   + G+W+  +Y    +    V+ 
Sbjct: 405 KTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEWNGVMYAKYATGENTVFV 464

Query: 735 --RANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQ 792
             +  P+ K   +         + NE +  S+SL    D  F      L+  +++ A   
Sbjct: 465 DTKKLPIIKKKVRKLE------DQNEYE--SRSLW--KDVTFN-----LKIRDIDAATEA 509

Query: 793 KQRIEQLQRERRRVLEENHVEHQPRFFRKSDDDSWVSNGTYLELRKDLGFSK 844
           K R+E+ QR   R  +E  ++ + R F + D + WV +   L   K LG +K
Sbjct: 510 KHRLEERQRAEARERKEKEIQWETRLFHE-DGECWVYDEPLL---KRLGAAK 557


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 76/371 (20%), Positives = 148/371 (39%), Gaps = 60/371 (16%)

Query: 500 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 559
           +G DL++V +P  + E  + L+   + + + +L        +  +RM+    + ++++  
Sbjct: 379 LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHE 438

Query: 560 SYYRA-GSKPFNPVLGETYECI------------------------------------RE 582
               A   KP+NP++GET+ C                                      +
Sbjct: 439 GRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSD 498

Query: 583 DKGFQFFSEQVSHHPPISACHAE--SRNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPV 640
               +F +EQVSHHPP+S  +AE   R       V  K+KF G S+ +  +G   ++L  
Sbjct: 499 CYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLE 558

Query: 641 FGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNAHEIE 700
            G+ + ++   +   +IL+   W+E  G++ + N         + F    ++    H + 
Sbjct: 559 HGEEYTFSLPCAYARSILT-VPWVELGGKVSV-NCAKTGYSASITFHTKPFYGGKLHRVT 616

Query: 701 GTV-FDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALELNEM 759
             V  + +   V R+ G+W+  +                   G  +Y   T+ A+    +
Sbjct: 617 AEVKHNITNTVVCRVQGEWNSVL-------------EFTYSNGETKYVDLTKLAVTKKRV 663

Query: 760 DPSSKSLLPPTDTR--FRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQPR 817
            P  K    P ++R  ++     L E  +++A   K  +E+ QR   R   E     + +
Sbjct: 664 RPLEKQ--DPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTK 721

Query: 818 FFRKSDDDSWV 828
           +F K + D WV
Sbjct: 722 YFIK-EGDGWV 731


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 37/113 (32%), Positives = 61/113 (53%), Gaps = 4/113 (3%)

Query: 46  NYTQEPPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSV 105
           N   EP  + G+LLK     +K W +R+F L  G L Y KS +D+ R K  G I++  S 
Sbjct: 698 NGKNEPLEKSGYLLKM-SGKVKSWKRRWFVLKGGELLYYKSPSDVIR-KPQGHIELSASC 755

Query: 106 MSVKKSSK-CIDLDTEEHIYHLKVKSEEVFDEWVSKLRH-HRMYRQNEIAMFP 156
             ++  +K  + L TE+H Y+L   S  + +EW+  L++  R+   N +++ P
Sbjct: 756 SILRGDNKQTVQLTTEKHTYYLTADSPNILEEWIKVLQNVLRVQAANPLSLQP 808


>gi|55741447 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 28/90 (31%), Positives = 49/90 (54%), Gaps = 3/90 (3%)

Query: 54  QKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVK-KSS 112
           + G+LLK     +K W +R+F L +G + Y KS +D+ R K  G +D+      V+ + S
Sbjct: 581 KSGYLLKMGS-QVKTWKRRWFVLRQGQIMYYKSPSDVIR-KPQGQVDLNSRCQIVRGEGS 638

Query: 113 KCIDLDTEEHIYHLKVKSEEVFDEWVSKLR 142
           +   L +E+  Y+L   S  + +EW+  L+
Sbjct: 639 QTFQLISEKKTYYLTADSPSLLEEWIRVLQ 668


>gi|46094081 development and differentiation enhancing factor 1
           [Homo sapiens]
          Length = 1129

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%)

Query: 4   DEKNLGVSQKLVSPSRSTSSCSSKQGSRQDSWEVVEGLRGEMNYTQEPPVQKGFLLKKRK 63
           ++K L   + L+  S         Q SRQ  + + + L+G   Y  E   +KG+LLKK  
Sbjct: 282 EKKQLTALRDLIKSSLQLDQKEDSQ-SRQGGYSMHQ-LQGNKEYGSE---KKGYLLKKSD 336

Query: 64  WPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVK---KSSKCIDLDTE 120
              K W +R   +  GIL  + + ++ +  KL+      L    VK   +  K  DL + 
Sbjct: 337 GIRKVWQRRKCSVKNGILTISHATSNRQPAKLN------LLTCQVKPNAEDKKSFDLISH 390

Query: 121 EHIYHLKVKSEEVFDEWVSKLRHHR 145
              YH + + E+ +  W+S L + +
Sbjct: 391 NRTYHFQAEDEQDYVAWISVLTNSK 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,438,493
Number of Sequences: 37866
Number of extensions: 1537136
Number of successful extensions: 5870
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 5585
Number of HSP's gapped (non-prelim): 293
length of query: 851
length of database: 18,247,518
effective HSP length: 111
effective length of query: 740
effective length of database: 14,044,392
effective search space: 10392850080
effective search space used: 10392850080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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