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Search of human proteins with 21618344
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21618344 signal transducer and activator of transcription 5B
[Homo sapiens]
(787 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21618344 signal transducer and activator of transcription 5B ... 1588 0.0
gi|21618342 signal transducer and activator of transcription 5A ... 1465 0.0
gi|23397678 signal transducer and activator of transcription 6 [... 454 e-127
gi|47458820 signal transducer and activator of transcription 3 i... 316 6e-86
gi|21618338 signal transducer and activator of transcription 3 i... 315 8e-86
gi|21618340 signal transducer and activator of transcription 3 i... 315 8e-86
gi|4507255 signal transducer and activator of transcription 4 [H... 310 3e-84
gi|6274552 signal transducer and activator of transcription 1 is... 298 2e-80
gi|21536301 signal transducer and activator of transcription 1 i... 298 2e-80
gi|4885615 signal transducer and activator of transcription 2 [H... 220 5e-57
gi|221139761 zinc finger protein 853 [Homo sapiens] 54 7e-07
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 47 9e-05
gi|34878777 ring finger protein 20 [Homo sapiens] 42 0.002
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 41 0.004
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 40 0.006
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 40 0.006
gi|50083279 centrosome protein 4 [Homo sapiens] 40 0.006
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 40 0.006
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 40 0.008
gi|38348729 hypothetical protein LOC203238 [Homo sapiens] 40 0.008
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 40 0.011
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 40 0.011
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 40 0.011
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 40 0.011
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 40 0.011
gi|81295809 pericentrin [Homo sapiens] 40 0.011
gi|21735548 centrosomal protein 2 [Homo sapiens] 39 0.014
gi|171906567 peripheral benzodiazepine receptor-associated prote... 39 0.014
gi|171906559 peripheral benzodiazepine receptor-associated prote... 39 0.014
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 39 0.019
>gi|21618344 signal transducer and activator of transcription 5B
[Homo sapiens]
Length = 787
Score = 1588 bits (4113), Expect = 0.0
Identities = 787/787 (100%), Positives = 787/787 (100%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL
Sbjct: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
Sbjct: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
Query: 121 REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL 180
REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
Sbjct: 121 REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL 180
Query: 181 RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL 240
RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
Sbjct: 181 RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL 240
Query: 241 RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC 300
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
Sbjct: 241 RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC 300
Query: 301 QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL 360
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
Sbjct: 301 QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL 360
Query: 361 NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS 420
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
Sbjct: 361 NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS 420
Query: 421 LKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA 480
LKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA
Sbjct: 421 LKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA 480
Query: 481 TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN 540
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
Sbjct: 481 TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN 540
Query: 541 SSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK 600
SSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK
Sbjct: 541 SSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK 600
Query: 601 QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL 660
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL
Sbjct: 601 QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL 660
Query: 661 GDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGG 720
GDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGG
Sbjct: 661 GDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGG 720
Query: 721 GSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQ 780
GSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQ
Sbjct: 721 GSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQ 780
Query: 781 WIPHAQS 787
WIPHAQS
Sbjct: 781 WIPHAQS 787
>gi|21618342 signal transducer and activator of transcription 5A
[Homo sapiens]
Length = 794
Score = 1465 bits (3792), Expect = 0.0
Identities = 731/779 (93%), Positives = 747/779 (95%), Gaps = 5/779 (0%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
MA WIQAQQLQG+AL QMQ LYGQHFPIEVRHYL+QWIESQ WD++DLDNPQ+ +ATQL
Sbjct: 1 MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQL 60
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQ TYDRCP+ELVRCIRHILYNEQRLV
Sbjct: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQKTYDRCPLELVRCIRHILYNEQRLV 120
Query: 121 REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL 180
REANN SSPAG L DAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
Sbjct: 121 REANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL 180
Query: 181 RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL 240
RIQAQF LAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
Sbjct: 181 RIQAQFAQLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL 240
Query: 241 RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC 300
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
Sbjct: 241 RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC 300
Query: 301 QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL 360
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
Sbjct: 301 QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL 360
Query: 361 NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS 420
NVHMNPPQVKATIISEQQAKSLLKNENTRN+ SGEILNNCCVMEYHQATGTLSAHFRNMS
Sbjct: 361 NVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMS 420
Query: 421 LKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA 480
LKRIKR+DRRGAESVTEEKFT+LFESQFSVG NELVFQVKTLSLPVVVIVHGSQD+NATA
Sbjct: 421 LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA 480
Query: 481 TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN 540
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
Sbjct: 481 TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN 540
Query: 541 SSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK 600
SSSHLEDYSGLSVSWSQFNRENLPG NYTFWQWFDGVMEVLKKH KPHWNDGAILGFVNK
Sbjct: 541 SSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK 600
Query: 601 QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL 660
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDS ER WNL PFTTRDFSIRSLADRL
Sbjct: 601 QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRL 660
Query: 661 GDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGG 720
GDL+YLIYVFPDRPKDEV+SKYYTPV AKAVDGYVKPQIKQVVPEFVNASADAGG
Sbjct: 661 GDLSYLIYVFPDRPKDEVFSKYYTPV-----LAKAVDGYVKPQIKQVVPEFVNASADAGG 715
Query: 721 GSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDS 779
SATYMDQAPSPAVCPQA YNMYPQNPD VLD DG+FDL++TMDVAR VEELL RPMDS
Sbjct: 716 SSATYMDQAPSPAVCPQAPYNMYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRPMDS 774
>gi|23397678 signal transducer and activator of transcription 6
[Homo sapiens]
Length = 847
Score = 454 bits (1169), Expect = e-127
Identities = 305/790 (38%), Positives = 434/790 (54%), Gaps = 89/790 (11%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
M++W ++ E ++Q LY FP +RH L W+ESQ W+ + + A+ L
Sbjct: 1 MSLWGLVSKMPPE---KVQRLYVD-FPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASAL 56
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
L VQ LQ Q GE +L+ H +T L++ Y R P++LV R IL E++ V
Sbjct: 57 LSDTVQHLQASVGEQ-GEGSTILQ----HIST-LESIYQRDPLKLVATFRQILQGEKKAV 110
Query: 121 REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL 180
E F L + + ELK ++ L
Sbjct: 111 MEQ------------------------FRHLPMPFHWKQEELK------------FKTGL 134
Query: 181 R-IQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQL 239
R +Q + G + L R + + + QVSL + ++ A LA Q+T
Sbjct: 135 RRLQHRVGEIHLL----REALQKGAEAGQVSLHSLIETPANGTGPSEA-LAMLLQETTGE 189
Query: 240 LRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHL 299
L + ++L I WKR+QQLAGNG P E SL LQ CE L +I Q +Q++ A
Sbjct: 190 LEAAKALVLKRIQI-WKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAG-- 246
Query: 300 CQQLPIPGPVE-EMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGG 358
G +E + A + + +++ LVTS F++EKQPPQVLKTQTKF A VR L+G
Sbjct: 247 -------GELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGL 299
Query: 359 K-LNVHMNPPQVKATIISEQQAKSLL--KNENTRNDYSGEILNNCCVMEYHQATGTLSAH 415
+ L PP V+A +++E+QA+ L + + +GEI+NN +E SA
Sbjct: 300 RFLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSAL 359
Query: 416 FRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQD 475
F+N+ LK+IKR +R+G ESVTEEK +LF + F++G +L Q++ LSLP+VVIVHG+QD
Sbjct: 360 FKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQD 419
Query: 476 NNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQ 535
NNA AT+LWDNAF+E RVPF V ++V W ++CE LN+KF AEV +NRGL E+ +FLAQ
Sbjct: 420 NNAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQ 479
Query: 536 KLFNNSSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAIL 595
K+FN++S +E + SVSWSQFN+E L GR +TFWQWFDGV+++ K+ L+ +W+D I+
Sbjct: 480 KIFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLII 539
Query: 596 GFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQE--RMFWNLMPFTTRDFSI 653
GF++KQ LL+N+PDGTFLLRFSDSEIGGITIA Q+ N+ PF+ +D SI
Sbjct: 540 GFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSI 599
Query: 654 RSLADRLGDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVV----- 708
RSL DR+ DL L ++P +PKDE + +Y P K GYV IK V
Sbjct: 600 RSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKP----EQMGKDGRGYVPATIKMTVERDQP 655
Query: 709 ---PEF----VNASADAGGGSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLED 761
PE + S D G + M P + PQ +YP + S+ G E+
Sbjct: 656 LPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQ----VYPPHSHSIPPYQG-LSPEE 710
Query: 762 TMDVARRVEE 771
+++V +E
Sbjct: 711 SVNVLSAFQE 720
>gi|47458820 signal transducer and activator of transcription 3
isoform 3 [Homo sapiens]
Length = 722
Score = 316 bits (809), Expect = 6e-86
Identities = 234/751 (31%), Positives = 380/751 (50%), Gaps = 69/751 (9%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
MA W Q QQL L Q+ LY FP+E+R +L+ WIESQ W + AT +
Sbjct: 1 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYA----ASKESHATLV 56
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
L+ E+ ++ + E L + L LQ+ Y PME+ R + L+ E RL+
Sbjct: 57 FHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL 116
Query: 121 REANNGSSPAGSL----ADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQY 176
+ A + G A +++K + Q +++R QD E ++K ++ Q+ F Y
Sbjct: 117 QTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNY 176
Query: 177 QESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKT 236
+ +L+ Q G + L+ + ++ +QK LE L L Q R + +
Sbjct: 177 K-TLKSQ---GDMQDLNG----NNQSVTRQKMQQLEQMLT----ALDQMRRSIVSELAGL 224
Query: 237 LQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRA 296
L + Q + D+EL WKRRQQ+A GGPP LD L++W LAE Q RQQI++
Sbjct: 225 LSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKL 284
Query: 297 EHLCQQLPIPG-PVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQVLKTQTK 347
E L Q++ G P+ + + I ++ L+ S F++E+QP P V+KT +
Sbjct: 285 EELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQ 344
Query: 348 FAATVRLLVG-GKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYH 406
F VRLLV +LN + ++K I + + L+ N N VM
Sbjct: 345 FTTKVRLLVKFPELNYQL---KIKVCIDKDSGDVAALRGSRKFNILG----TNTKVMNME 397
Query: 407 QAT-GTLSAHFRNMSLKRIK-----RSDRRGAESVTEEKFTILFESQFSVGGNELVFQVK 460
++ G+LSA F++++L+ + R++ + VTEE I FE++ G L ++
Sbjct: 398 ESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQG--LKIDLE 455
Query: 461 TLSLPVVVIVHGSQDNNATATVLWDNAFAE-PGRVPFAVPDKV-LWPQLCEALNMKFKAE 518
T SLPVVVI + Q NA A++LW N P V F + W Q+ E L+ +F +
Sbjct: 456 THSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSST 515
Query: 519 VQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVM 578
+ RGL+ E L LA+KL + YSG ++W++F +EN+ G+ ++FW W D ++
Sbjct: 516 TK--RGLSIEQLTTLAEKLLGPGVN----YSGCQITWAKFCKENMAGKGFSFWVWLDNII 569
Query: 579 EVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSD-SEIGGITIAW--KFDS 635
+++KK++ WN+G I+GF++K++ +L KP GTFLLRFS+ S+ GG+T W K S
Sbjct: 570 DLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDIS 629
Query: 636 QERMFWNLMPFTTRDFSIRSLAD-----RLGD-----LNYLIYVFPDRPKDEVYSKYYTP 685
+ ++ P+T + + S A+ ++ D ++ L+Y++PD PK+E + KY P
Sbjct: 630 GKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRP 689
Query: 686 VPCE--SATAKAVDGYVKPQIKQVVPEFVNA 714
E A + Y+K + V P F++A
Sbjct: 690 ESQEHPEADPGSAAPYLKTKFICVTP-FIDA 719
>gi|21618338 signal transducer and activator of transcription 3
isoform 2 [Homo sapiens]
Length = 769
Score = 315 bits (808), Expect = 8e-86
Identities = 231/740 (31%), Positives = 373/740 (50%), Gaps = 69/740 (9%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
MA W Q QQL L Q+ LY FP+E+R +L+ WIESQ W + AT +
Sbjct: 1 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYA----ASKESHATLV 56
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
L+ E+ ++ + E L + L LQ+ Y PME+ R + L+ E RL+
Sbjct: 57 FHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL 116
Query: 121 REANNGSSPAGSL----ADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQY 176
+ A + G A +++K + Q +++R QD E ++K ++ Q+ F Y
Sbjct: 117 QTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNY 176
Query: 177 QESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKT 236
+ +L+ Q G + L+ + ++ +QK LE L L Q R + +
Sbjct: 177 K-TLKSQ---GDMQDLNG----NNQSVTRQKMQQLEQMLT----ALDQMRRSIVSELAGL 224
Query: 237 LQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRA 296
L + Q + D+EL WKRRQQ+A GGPP LD L++W LAE Q RQQI++
Sbjct: 225 LSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKL 284
Query: 297 EHLCQQLPIPG-PVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQVLKTQTK 347
E L Q++ G P+ + + I ++ L+ S F++E+QP P V+KT +
Sbjct: 285 EELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQ 344
Query: 348 FAATVRLLVG-GKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYH 406
F VRLLV +LN + ++K I + + L+ N N VM
Sbjct: 345 FTTKVRLLVKFPELNYQL---KIKVCIDKDSGDVAALRGSRKFNILG----TNTKVMNME 397
Query: 407 QAT-GTLSAHFRNMSLKRIK-----RSDRRGAESVTEEKFTILFESQFSVGGNELVFQVK 460
++ G+LSA F++++L+ + R++ + VTEE I FE++ G L ++
Sbjct: 398 ESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQG--LKIDLE 455
Query: 461 TLSLPVVVIVHGSQDNNATATVLWDNAFAE-PGRVPFAVPDKV-LWPQLCEALNMKFKAE 518
T SLPVVVI + Q NA A++LW N P V F + W Q+ E L+ +F +
Sbjct: 456 THSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSST 515
Query: 519 VQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVM 578
+ RGL+ E L LA+KL + YSG ++W++F +EN+ G+ ++FW W D ++
Sbjct: 516 TK--RGLSIEQLTTLAEKLLGPGVN----YSGCQITWAKFCKENMAGKGFSFWVWLDNII 569
Query: 579 EVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSD-SEIGGITIAW--KFDS 635
+++KK++ WN+G I+GF++K++ +L KP GTFLLRFS+ S+ GG+T W K S
Sbjct: 570 DLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDIS 629
Query: 636 QERMFWNLMPFTTRDFSIRSLAD-----RLGD-----LNYLIYVFPDRPKDEVYSKYYTP 685
+ ++ P+T + + S A+ ++ D ++ L+Y++PD PK+E + KY P
Sbjct: 630 GKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRP 689
Query: 686 VPCESATAKAVDGYVKPQIK 705
ES D P +K
Sbjct: 690 ---ESQEHPEADPGAAPYLK 706
>gi|21618340 signal transducer and activator of transcription 3
isoform 1 [Homo sapiens]
Length = 770
Score = 315 bits (808), Expect = 8e-86
Identities = 233/754 (30%), Positives = 379/754 (50%), Gaps = 68/754 (9%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
MA W Q QQL L Q+ LY FP+E+R +L+ WIESQ W + AT +
Sbjct: 1 MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYA----ASKESHATLV 56
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
L+ E+ ++ + E L + L LQ+ Y PME+ R + L+ E RL+
Sbjct: 57 FHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL 116
Query: 121 REANNGSSPAGSL----ADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQY 176
+ A + G A +++K + Q +++R QD E ++K ++ Q+ F Y
Sbjct: 117 QTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNY 176
Query: 177 QESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKT 236
+ +L+ Q G + L+ + ++ +QK LE L L Q R + +
Sbjct: 177 K-TLKSQ---GDMQDLNG----NNQSVTRQKMQQLEQMLT----ALDQMRRSIVSELAGL 224
Query: 237 LQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRA 296
L + Q + D+EL WKRRQQ+A GGPP LD L++W LAE Q RQQI++
Sbjct: 225 LSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKL 284
Query: 297 EHLCQQLPIPG-PVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQVLKTQTK 347
E L Q++ G P+ + + I ++ L+ S F++E+QP P V+KT +
Sbjct: 285 EELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQ 344
Query: 348 FAATVRLLVG-GKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYH 406
F VRLLV +LN + ++K I + + L+ N N VM
Sbjct: 345 FTTKVRLLVKFPELNYQL---KIKVCIDKDSGDVAALRGSRKFNILG----TNTKVMNME 397
Query: 407 QAT-GTLSAHFRNMSLKRIK-----RSDRRGAESVTEEKFTILFESQFSVGGNELVFQVK 460
++ G+LSA F++++L+ + R++ + VTEE I FE++ G L ++
Sbjct: 398 ESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQG--LKIDLE 455
Query: 461 TLSLPVVVIVHGSQDNNATATVLWDNAFAE-PGRVPFAVPDKV-LWPQLCEALNMKFKAE 518
T SLPVVVI + Q NA A++LW N P V F + W Q+ E L+ +F +
Sbjct: 456 THSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSST 515
Query: 519 VQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVM 578
+ RGL+ E L LA+KL + YSG ++W++F +EN+ G+ ++FW W D ++
Sbjct: 516 TK--RGLSIEQLTTLAEKLLGPGVN----YSGCQITWAKFCKENMAGKGFSFWVWLDNII 569
Query: 579 EVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSD-SEIGGITIAW--KFDS 635
+++KK++ WN+G I+GF++K++ +L KP GTFLLRFS+ S+ GG+T W K S
Sbjct: 570 DLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDIS 629
Query: 636 QERMFWNLMPFTTRDFSIRSLAD-----RLGD-----LNYLIYVFPDRPKDEVYSKYYTP 685
+ ++ P+T + + S A+ ++ D ++ L+Y++PD PK+E + KY P
Sbjct: 630 GKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRP 689
Query: 686 VPCE--SATAKAVDGYVKPQIKQVVPEFVNASAD 717
E A + Y+K + V P + + D
Sbjct: 690 ESQEHPEADPGSAAPYLKTKFICVTPTTCSNTID 723
>gi|4507255 signal transducer and activator of transcription 4 [Homo
sapiens]
Length = 748
Score = 310 bits (794), Expect = 3e-84
Identities = 229/732 (31%), Positives = 362/732 (49%), Gaps = 70/732 (9%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
M+ W Q QQL+ + L Q+ Y +FP+E+RH L+QWIE+Q W++ AT L
Sbjct: 1 MSQWNQVQQLEIKFLEQVDQFYDDNFPMEIRHLLAQWIENQDWEAAS----NNETMATIL 56
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
L+ L+ +L ++ E LL L LQ + PM + I + L E+R++
Sbjct: 57 LQNLLIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGKFHGNPMHVAVVISNCLREERRIL 116
Query: 121 REAN---NGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQ 177
AN G + ++S++ + ++ Q TE + K L+ Q+ F +Y+
Sbjct: 117 AAANMPVQGPLEKSLQSSSVSERQRNVEHKVAAIKNSVQMTEQDTKYLEDLQDEFDYRYK 176
Query: 178 ESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTL 237
+ ++ + +A+ ++V LQ +L R E K + +
Sbjct: 177 T-------------IQTMDQSDKNSAMVNQEVLT---LQEMLNSLDFKRKEALSKMTQII 220
Query: 238 QLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAE 297
+L +EL WKRRQQ+A GGP LD LQ+ LAE ++Q R+Q+ + E
Sbjct: 221 HETDLLMNTMLIEELQDWKRRQQIACIGGPLHNGLDQLQNCFTLLAESLFQLRRQLEKLE 280
Query: 298 HLCQQLPIPG-PVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQVLKTQTKF 348
++ G P+ + +T +I L ++F++E+QP P VLKT +F
Sbjct: 281 EQSTKMTYEGDPIPMQRTHMLERVTFLIYNLFKNSFVVERQPCMPTHPQRPLVLKTLIQF 340
Query: 349 AATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQA 408
+RLL+ KL +VKA+I K++ N R G + + E +
Sbjct: 341 TVKLRLLI--KLPELNYQVKVKASI-----DKNVSTLSNRRFVLCGTNVKAMSIEE--SS 391
Query: 409 TGTLSAHFRNMSLKRIKRS----DRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSL 464
G+LS FR++ K +K S G VTEE +I FE+Q + G L ++T SL
Sbjct: 392 NGSLSVEFRHLQPKEMKSSAGGKGNEGCHMVTEELHSITFETQICLYG--LTIDLETSSL 449
Query: 465 PVVVIVHGSQDNNATATVLWDNAFAEPGR--VPFAVPDKVLWPQLCEALNMKFKAEVQSN 522
PVV+I + SQ NA A+++W N + V F P QL E ++ +F + V
Sbjct: 450 PVVMISNVSQLPNAWASIIWYNVSTNDSQNLVFFNNPPPATLSQLLEVMSWQFSSYV--G 507
Query: 523 RGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLK 582
RGL + L LA+KL SS YS ++W++F +E+LPG+++TFW W + +++++K
Sbjct: 508 RGLNSDQLHMLAEKLTVQSS-----YSDGHLTWAKFCKEHLPGKSFTFWTWLEAILDLIK 562
Query: 583 KHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAW--KFDSQERMF 640
KH+ P W DG ++GFV+K++ LL +K GTFLLRFS+S +GGIT W +S E F
Sbjct: 563 KHILPLWIDGYVMGFVSKEKERLLLKDKMPGTFLLRFSESHLGGITFTWVDHSESGEVRF 622
Query: 641 WNLMPFTTRDFSIRSLADRLGDL----------NYLIYVFPDRPKDEVYSKYYTPVPCES 690
++ P+ S AD L D N L Y++PD PKD+ + K+Y+ PCE
Sbjct: 623 HSVEPYNKGRLSALPFADILRDYKVIMAENIPENPLKYLYPDIPKDKAFGKHYSSQPCEV 682
Query: 691 A--TAKAVDGYV 700
+ T + GYV
Sbjct: 683 SRPTERGDKGYV 694
>gi|6274552 signal transducer and activator of transcription 1
isoform alpha [Homo sapiens]
Length = 750
Score = 298 bits (762), Expect = 2e-80
Identities = 231/749 (30%), Positives = 371/749 (49%), Gaps = 82/749 (10%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
M+ W + QQL + L Q+ LY FP+E+R YL+QW+E Q W+ D I+ L
Sbjct: 1 MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDL 60
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
L L + + + E+ FLL+ + LQ+ + P+++ I L E++++
Sbjct: 61 LSQLDDQYSRFSL----ENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKIL 116
Query: 121 REAN--NGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQE 178
A N + + M K +++ ++ E+E+K L+ Q+ + + +
Sbjct: 117 ENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKT 176
Query: 179 SLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQ 238
+ + +A+ QKQ L L++ L R E+ K + L
Sbjct: 177 LQNREHETNGVAKSD------------QKQEQL--LLKKMYLMLDNKRKEVVHKIIELLN 222
Query: 239 LLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEH 298
+ Q +++DEL++WKRRQQ A GGPP LD LQ+W +AE + Q RQQ+++ E
Sbjct: 223 VTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEE 282
Query: 299 LCQQLPIP-GPVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQVLKTQTKFA 349
L Q+ P+ + + + L+ S+F++E+QP P VLKT +F
Sbjct: 283 LEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFT 342
Query: 350 ATVRLLVG-GKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSG----EILN-NCCVM 403
+RLLV +LN ++ K ++ + K+ N RN G IL + VM
Sbjct: 343 VKLRLLVKLQELNYNL-----KVKVLFD-------KDVNERNTVKGFRKFNILGTHTKVM 390
Query: 404 EYHQAT-GTLSAHFRNMSLKRIKRSDRRGAES---VTEEKFTILFESQFSVGGNELVFQV 459
++T G+L+A FR++ LK K + R E VTEE ++ FE+Q G LV +
Sbjct: 391 NMEESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPG--LVIDL 448
Query: 460 KTLSLPVVVIVHGSQDNNATATVLWDNAF-AEPGRVPFAV-PDKVLWPQLCEALNMKFKA 517
+T SLPVVVI + SQ + A++LW N AEP + F + P W QL E L+ +F +
Sbjct: 449 ETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSS 508
Query: 518 EVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGV 577
+ RGL + L L +KL ++S GL + W++F +EN+ +N+ FW W + +
Sbjct: 509 VTK--RGLNVDQLNMLGEKLLGPNASP----DGL-IPWTRFCKENINDKNFPFWLWIESI 561
Query: 578 MEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSD-SEIGGITIAWKFDSQ 636
+E++KKHL P WNDG I+GF++K++ LL ++ GTFLLRFS+ S G IT W SQ
Sbjct: 562 LELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQ 621
Query: 637 ---ERMFWNLMPFTTRDFSIRSLADRLGDL----------NYLIYVFPDRPKDEVYSKYY 683
E F + P+T ++ S + D + + N L Y++P+ KD + KYY
Sbjct: 622 NGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYY 681
Query: 684 T-----PVPCESATAKAVDGYVKPQIKQV 707
+ P P E K GY+K ++ V
Sbjct: 682 SRPKEAPEPMELDGPKGT-GYIKTELISV 709
>gi|21536301 signal transducer and activator of transcription 1
isoform beta [Homo sapiens]
Length = 712
Score = 298 bits (762), Expect = 2e-80
Identities = 231/749 (30%), Positives = 371/749 (49%), Gaps = 82/749 (10%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL 60
M+ W + QQL + L Q+ LY FP+E+R YL+QW+E Q W+ D I+ L
Sbjct: 1 MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDL 60
Query: 61 LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
L L + + + E+ FLL+ + LQ+ + P+++ I L E++++
Sbjct: 61 LSQLDDQYSRFSL----ENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKIL 116
Query: 121 REAN--NGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQE 178
A N + + M K +++ ++ E+E+K L+ Q+ + + +
Sbjct: 117 ENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKT 176
Query: 179 SLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQ 238
+ + +A+ QKQ L L++ L R E+ K + L
Sbjct: 177 LQNREHETNGVAKSD------------QKQEQL--LLKKMYLMLDNKRKEVVHKIIELLN 222
Query: 239 LLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEH 298
+ Q +++DEL++WKRRQQ A GGPP LD LQ+W +AE + Q RQQ+++ E
Sbjct: 223 VTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEE 282
Query: 299 LCQQLPIP-GPVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQVLKTQTKFA 349
L Q+ P+ + + + L+ S+F++E+QP P VLKT +F
Sbjct: 283 LEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFT 342
Query: 350 ATVRLLVG-GKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSG----EILN-NCCVM 403
+RLLV +LN ++ K ++ + K+ N RN G IL + VM
Sbjct: 343 VKLRLLVKLQELNYNL-----KVKVLFD-------KDVNERNTVKGFRKFNILGTHTKVM 390
Query: 404 EYHQAT-GTLSAHFRNMSLKRIKRSDRRGAES---VTEEKFTILFESQFSVGGNELVFQV 459
++T G+L+A FR++ LK K + R E VTEE ++ FE+Q G LV +
Sbjct: 391 NMEESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPG--LVIDL 448
Query: 460 KTLSLPVVVIVHGSQDNNATATVLWDNAF-AEPGRVPFAV-PDKVLWPQLCEALNMKFKA 517
+T SLPVVVI + SQ + A++LW N AEP + F + P W QL E L+ +F +
Sbjct: 449 ETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSS 508
Query: 518 EVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGV 577
+ RGL + L L +KL ++S GL + W++F +EN+ +N+ FW W + +
Sbjct: 509 VTK--RGLNVDQLNMLGEKLLGPNASP----DGL-IPWTRFCKENINDKNFPFWLWIESI 561
Query: 578 MEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSD-SEIGGITIAWKFDSQ 636
+E++KKHL P WNDG I+GF++K++ LL ++ GTFLLRFS+ S G IT W SQ
Sbjct: 562 LELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQ 621
Query: 637 ---ERMFWNLMPFTTRDFSIRSLADRLGDL----------NYLIYVFPDRPKDEVYSKYY 683
E F + P+T ++ S + D + + N L Y++P+ KD + KYY
Sbjct: 622 NGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYY 681
Query: 684 T-----PVPCESATAKAVDGYVKPQIKQV 707
+ P P E K GY+K ++ V
Sbjct: 682 SRPKEAPEPMELDGPKGT-GYIKTELISV 709
>gi|4885615 signal transducer and activator of transcription 2 [Homo
sapiens]
Length = 851
Score = 220 bits (560), Expect = 5e-57
Identities = 196/730 (26%), Positives = 329/730 (45%), Gaps = 99/730 (13%)
Query: 1 MAVWIQAQQLQGEALHQMQALYGQHF-PIEVRHYLSQWIESQAWDSVDLDNPQENIKATQ 59
MA W Q L Q+ LY P+++R YL+ WIE Q W L + ++ KAT
Sbjct: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGS--DDSKATM 58
Query: 60 LLEGLVQELQKKAEH-QVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQR 118
L + +L + + LL+ L + +Q + + P +L I ++L E+R
Sbjct: 59 LFFHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQ-PFSQDPTQLAEMIFNLLLEEKR 117
Query: 119 LVREANNGSSPAGS--LADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQY 176
++ +A G L + + +I +LR + + + +L+ Q+ F +Y
Sbjct: 118 ILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRY 177
Query: 177 QESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKT 236
+IQA+ K SL+ +E + LQ+ EL ++ ++
Sbjct: 178 ----KIQAK--------------------GKTPSLDPHQTKEQKILQETLNELDKRRKEV 213
Query: 237 LQ----LLRKQQTII--LDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNR 290
L LL + T+I L +L +WK +QQ A P + L+ L++W A++++ R
Sbjct: 214 LDASKALLGRLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLR 273
Query: 291 QQIRRAEHL-CQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQV 341
Q ++ + L C P+ + + NA +T+++ L+ F++E QP P +
Sbjct: 274 QLLKELKGLSCLVSYQDDPLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLI 333
Query: 342 LKTQTKFAATVRLLVG---------GKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDY 392
LKT +KF RLLV ++++ NPPQ++ ++ L N+ T
Sbjct: 334 LKTGSKFTVRTRLLVRLQEGNESLTVEVSIDRNPPQLQGF----RKFNILTSNQKTLTPE 389
Query: 393 SGEILNNCCVMEYHQATGTLSAHFRNMSLKRIK-----RSDRRGAESVTEEKFTILFESQ 447
G Q+ G L F ++L + + +G VTEE I F +
Sbjct: 390 KG------------QSQG-LIWDFGYLTLVEQRSGGSGKGSNKGPLGVTEELHIISFTVK 436
Query: 448 FSVGGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAE--PGRVPFAVPDKVLWP 505
++ G L ++KT +LPVV+I + +Q + A A+VLW N + + F+ P K W
Sbjct: 437 YTYQG--LKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWS 494
Query: 506 QLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPG 565
L AL+ +F + V RGL + L L KLF + + +SW+ F + P
Sbjct: 495 LLGPALSWQFSSYV--GRGLNSDQLSMLRNKLFGQNCRTEDPL----LSWADFTKRESPP 548
Query: 566 RNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIG 625
FW W D ++E++ HLK WNDG I+GFV++ Q LL GTFLLRFS+S G
Sbjct: 549 GKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEG 608
Query: 626 GITIAW--KFDSQERMFWNLMPFTTRDFSIRSLADRLGDL----------NYLIYVFPDR 673
GIT +W D + + +++ P+T L + + N L +++P
Sbjct: 609 GITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPRI 668
Query: 674 PKDEVYSKYY 683
P+DE + YY
Sbjct: 669 PRDEAFGCYY 678
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 53.5 bits (127), Expect = 7e-07
Identities = 47/174 (27%), Positives = 83/174 (47%), Gaps = 18/174 (10%)
Query: 139 QKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERL 198
Q+ LQ Q E+ RL Q E + QQ QE ++Q QE L+ Q Q L Q ++
Sbjct: 156 QQQLQPQQVQEQQRLQQQQ---EQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212
Query: 199 SRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRR 258
++ QQ+Q+ + + Q++ Q QQ ++ L ++ + Q L +QQ L +L++ ++
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQA 272
Query: 259 QQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQI--RRAEHLCQQLPIPGPVE 310
Q Q ++ ++ Q +QQ+ ++ E L QQ P P+E
Sbjct: 273 QLQQ-------------QLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLE 313
Score = 42.7 bits (99), Expect = 0.001
Identities = 66/302 (21%), Positives = 121/302 (40%), Gaps = 48/302 (15%)
Query: 6 QAQQLQGEALHQMQALYGQHFPIEVR--HYLSQWIESQAWDSVDLDNPQENIKATQLLEG 63
Q QLQ E + Q+++ Q E++ H Q Q + L QE ++ Q E
Sbjct: 129 QLSQLQQE---KHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQ 185
Query: 64 LVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREA 123
V + Q++ + QV E L + + QL ++ + + + L +Q+L+
Sbjct: 186 QVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQ 245
Query: 124 NNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQ 183
G L +Q Q+ + ++ +L Q + ++LQQ Q+ ++Q Q+ Q
Sbjct: 246 QQGQLQQQLLQQQQAQLQQQLLEQ-QQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQ 304
Query: 184 AQFGP-----------------------------LAQLSPQERLSRETALQQKQVSL--- 211
Q P +L Q+ L R+ +Q Q+ L
Sbjct: 305 QQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEE 364
Query: 212 ----EAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQL---AGN 264
E L+++ Q L+Q V+L ++L +QQ + L+ +Q + + +L AG
Sbjct: 365 LQQLEQQLEQQQQQLEQQEVQL---ELTPVELGAQQQEVQLELTPVQPELQLELVPAAGG 421
Query: 265 GG 266
GG
Sbjct: 422 GG 423
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 46.6 bits (109), Expect = 9e-05
Identities = 102/464 (21%), Positives = 189/464 (40%), Gaps = 79/464 (17%)
Query: 62 EGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCP-----MELVRCIRHILYNE 116
E + L+K + + +D LL H ++QL+++Y++ M ++ R L+NE
Sbjct: 2797 ENSLSHLEKLNQQLLSKDEQLL-----HLSSQLEDSYNQVQSFSKAMASLQNERDHLWNE 2851
Query: 117 QRLVREANNG---------SSPAG--SLADAMS-----------------QKHLQINQTF 148
R++ G +SPA SL AMS Q++LQINQ
Sbjct: 2852 LEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEI 2911
Query: 149 EELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALQQKQ 208
EL + + +L++ Q + F I QE LR QE LS + L Q +
Sbjct: 2912 TELHPL----KAQLQEYQDKTKAFQIM-QEELR-------------QENLSWQHELHQLR 2953
Query: 209 VSLEAWLQREAQTLQQYRVELAEKHQK---TLQLLRKQQTIILDDELIQWK-RRQQLAGN 264
+ +W E + +QY + +++K Q+ L+R+ ++ + ++ + +RQ
Sbjct: 2954 MEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPET 3013
Query: 265 GGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDII 324
P+GS +++ E L + + ++I + E QQL ++L E N T I
Sbjct: 3014 SASPDGSQNLVYE-TELLRTQLNDSLKEIHQKELRIQQL--NSNFSQLLEEKN---TLSI 3067
Query: 325 SALVTSTFIIEKQP--PQVLKTQTKFAATVRLLVGGKLNVHMNP--PQVKATIISEQQAK 380
TS + E Q +L V+ L G LN+ + P PQ K + + +
Sbjct: 3068 QLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPE 3127
Query: 381 SLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSDRRGAESVTEEKF 440
L + + + ++ ++ N Q L + + +R +R A SV EE+
Sbjct: 3128 ELREPQQSFSEAQQQLCNT------RQEVNELR---KLLEEERDQRVAAENALSVAEEQI 3178
Query: 441 TILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATATVLW 484
L S++ ++ T +++ + + + V W
Sbjct: 3179 RRLEHSEWDSSRTPIIGSCGTQEQALLIDLTSNSCRRTRSGVGW 3222
Score = 31.2 bits (69), Expect = 3.9
Identities = 26/124 (20%), Positives = 60/124 (48%), Gaps = 10/124 (8%)
Query: 115 NEQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFII 174
++++LV+E + S + + +KH ++ + +E L ++ NE +++Q E
Sbjct: 1582 DKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ 1641
Query: 175 QYQESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAW---LQREAQTLQQYRVELAE 231
+ QE +G L ++ E LQ+ + +E +++ A++ QQ +EL E
Sbjct: 1642 EKQE------LYGKLRSTEANKK-ETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEE 1694
Query: 232 KHQK 235
++ +
Sbjct: 1695 ENDR 1698
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/146 (26%), Positives = 75/146 (51%), Gaps = 11/146 (7%)
Query: 126 GSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQE-SLRIQA 184
GSS G ++K ++N EE + + Q+ EL+KL+Q E Q ++ + +++
Sbjct: 310 GSSLYGGTITINARKFEEMNAELEENKELAQNRLCELEKLRQDFEEVTTQNEKLKVELRS 369
Query: 185 QFGPLAQLSPQERL--SRETALQQKQVSLEAWLQREAQTL-------QQYRVELAEKHQK 235
+ + +P+ R S+ + L + + L+A L EA+TL Q++VEL E+ +
Sbjct: 370 AVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLD-EARTLLHGTRGTHQHQVELIERDEV 428
Query: 236 TLQLLRKQQTIILDDELIQWKRRQQL 261
+L + + I L+D L Q ++ ++
Sbjct: 429 SLHKKLRTEVIQLEDTLAQVRKEYEM 454
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 41.2 bits (95), Expect = 0.004
Identities = 80/412 (19%), Positives = 164/412 (39%), Gaps = 61/412 (14%)
Query: 29 EVRHYLSQWIESQAWDSVDLDNPQENIKATQLLEGLVQE----LQKKAEHQVGEDGFLLK 84
E R L ++ Q +++ + +E I Q L + QE ++K +E Q+ + L +
Sbjct: 428 EARRKLKAEMDEQI-KTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHE 486
Query: 85 IKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGSSPAGSLADAMSQKHLQI 144
+L +L E + EQ V + S + Q+ L +
Sbjct: 487 KELARKEQELTKKLQTRERE---------FQEQMKVALEKSQSEYLKISQEKEQQESLAL 537
Query: 145 NQTFEELRLVTQDTENELKKLQQTQEYF---IIQYQESLRIQAQFGPLAQLSPQERLSRE 201
+ + + + ++EN+L+ LQQ E + I++ + SL E+ +E
Sbjct: 538 EELELQKKAILTESENKLRDLQQEAETYRTRILELESSL---------------EKSLQE 582
Query: 202 TALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQL 261
Q K +++ L+ E + + EKH+ L+ L+ QQ + ++L K++
Sbjct: 583 NKNQSKDLAVH--LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQ--- 637
Query: 262 AGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATIT 321
Q+ EKL E Q ++ + + + + Q I E+ L +++ T
Sbjct: 638 -------------YQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQT 684
Query: 322 DIISALVTSTFIIE-----KQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISE 376
++ S + +++ ++ VLK QT ++ + K++ N Q + I +
Sbjct: 685 ELESLSSELSEVLKARHKLEEELSVLKDQTD---KMKQELEAKMDEQKNHHQQQVDSIIK 741
Query: 377 QQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSD 428
+ S+ + E D ++ + E + AH N+ IKRS+
Sbjct: 742 EHEVSIQRTEKALKDQINQL--ELLLKERDKHLKEHQAHVENLEAD-IKRSE 790
Score = 40.8 bits (94), Expect = 0.005
Identities = 53/195 (27%), Positives = 86/195 (44%), Gaps = 35/195 (17%)
Query: 149 EELRLVTQDTENEL----KKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRE--T 202
++LR++ ++ + EL K+ Q +E I Q QE L ++ S ++L RE T
Sbjct: 1951 KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHN-------STLKQLMREFNT 2003
Query: 203 ALQQKQVSLEAWLQREAQTLQQYRVELAEKHQ-KTLQLLRKQQTIILDDELIQWKRRQQL 261
L QK+ LE ++ Q+ EL E HQ +T QLL+K DD+L + +R +
Sbjct: 2004 QLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKK--IAEKDDDLKRTAKRYEE 2061
Query: 262 AGNGGPPEGSLDV--LQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNAT 319
+ E + V LQ+ E+L + Q +Q EE N T
Sbjct: 2062 ILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ-----------------EENPGNDNVT 2104
Query: 320 ITDIISALVTSTFII 334
I ++ + L T +I
Sbjct: 2105 IMELQTQLAQKTTLI 2119
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 40.4 bits (93), Expect = 0.006
Identities = 62/313 (19%), Positives = 133/313 (42%), Gaps = 31/313 (9%)
Query: 5 IQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQLLEGL 64
++A +L E L Q E+ + L+Q E + W + QE Q L+
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321
Query: 65 VQE----LQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
QE Q++ H+ E KI+ Q R E +R ++ ++ +
Sbjct: 322 EQEEKMWRQEEKMHEQEE-----KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 121 REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENEL----KKLQQTQEYFIIQY 176
RE + + + ++ ++ + E++R + + ++ KK+++ E Q
Sbjct: 377 REQD----------EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 177 QESLRIQAQFGPLAQL-SPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQK 235
+E R + + L ++ QE RE +++K E +Q + + +Q+ ++ E+ +K
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLRE--VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 236 TL--QLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAE---IIWQNR 290
T + L KQ+ I + E W++ +++ + + +Q EK+ E +WQ
Sbjct: 485 TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 291 QQIRRAEHLCQQL 303
++++ E Q+L
Sbjct: 545 EKMQEQEVRLQEL 557
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 40.4 bits (93), Expect = 0.006
Identities = 62/313 (19%), Positives = 133/313 (42%), Gaps = 31/313 (9%)
Query: 5 IQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQLLEGL 64
++A +L E L Q E+ + L+Q E + W + QE Q L+
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321
Query: 65 VQE----LQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV 120
QE Q++ H+ E KI+ Q R E +R ++ ++ +
Sbjct: 322 EQEEKMWRQEEKMHEQEE-----KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 121 REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENEL----KKLQQTQEYFIIQY 176
RE + + + ++ ++ + E++R + + ++ KK+++ E Q
Sbjct: 377 REQD----------EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE 426
Query: 177 QESLRIQAQFGPLAQL-SPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQK 235
+E R + + L ++ QE RE +++K E +Q + + +Q+ ++ E+ +K
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLRE--VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 236 TL--QLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAE---IIWQNR 290
T + L KQ+ I + E W++ +++ + + +Q EK+ E +WQ
Sbjct: 485 TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 291 QQIRRAEHLCQQL 303
++++ E Q+L
Sbjct: 545 EKMQEQEVRLQEL 557
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 40.4 bits (93), Expect = 0.006
Identities = 43/203 (21%), Positives = 95/203 (46%), Gaps = 12/203 (5%)
Query: 47 DLDNPQENIKATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQ---LQNTYDRCPM 103
+L++ Q IK +LE + EL K Q E+ ++K +G + LQ T D
Sbjct: 693 ELESAQAQIK---ILEEKIDELNLKMTSQ-DEEAHVMKKTIGVIDKEKDFLQETVDE-KT 747
Query: 104 ELVRCIRHILYNEQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELK 163
E + ++ L N+++ V + S S + + + + ++ LR EL
Sbjct: 748 EKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQLDAAHKELD 807
Query: 164 KLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQ 223
++ +++E I ++E+ R+Q +A+ + + L E A+Q+K+ +++ + + +
Sbjct: 808 EVGRSRE---IAFKENRRLQDDLATMARENQEISLELEAAVQEKE-EMKSRVHKYITEVS 863
Query: 224 QYRVELAEKHQKTLQLLRKQQTI 246
++ +A K ++ LL + Q +
Sbjct: 864 RWESLMAAKEKENQDLLDRFQML 886
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 40.4 bits (93), Expect = 0.006
Identities = 56/290 (19%), Positives = 113/290 (38%), Gaps = 28/290 (9%)
Query: 109 IRHILYNEQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQT 168
+R + +L R+ + + ++ + +K +N EEL V + L T
Sbjct: 1831 VRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHT 1890
Query: 169 QEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRV- 227
++ + E R+Q A + ET QQ QV + + + +QQ +
Sbjct: 1891 TKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMF 1950
Query: 228 -------ELAEKHQKTLQLLRKQQTIILDDELIQWKRR-QQLAGNGGPPEGSLDVLQS-- 277
E E +T ++ K+Q L+ EL K + Q+ E + LQ
Sbjct: 1951 QRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEE 2010
Query: 278 -WCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEK 336
WCE L + + Q ++Q+ E Q + G + + E ++ D +L+ + F+ E+
Sbjct: 2011 RWCESLEKTLSQTKRQLSEREQ--QLVEKSGELLALQKEADSMRADF--SLLRNQFLTER 2066
Query: 337 QPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNE 386
+ + K A ++ Q++ ++ ++Q S ++ E
Sbjct: 2067 KKAEKQVASLKEALKIQ------------RSQLEKNLLEQKQENSCIQKE 2104
Score = 34.3 bits (77), Expect = 0.46
Identities = 31/142 (21%), Positives = 65/142 (45%), Gaps = 24/142 (16%)
Query: 135 DAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSP 194
+ + Q+ ++ Q ++L +V D EN K+L + + Q++ + +Q G L+
Sbjct: 647 ETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEA 706
Query: 195 Q-------------------ERLSRETALQQKQVSLEAWLQREAQTLQQYRVEL---AEK 232
+ E+++R T L+Q +L+A L++E Q L+ + EK
Sbjct: 707 ELEARLNLRDAEANQLKEELEKVTRLTQLEQS--ALQAELEKERQALKNALGKAQFSEEK 764
Query: 233 HQKTLQLLRKQQTIILDDELIQ 254
Q+ +L K + + D+ L++
Sbjct: 765 EQENSELHAKLKHLQDDNNLLK 786
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.008
Identities = 52/239 (21%), Positives = 105/239 (43%), Gaps = 19/239 (7%)
Query: 30 VRHYLSQWIESQAWDSVDLDNPQENIKATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGH 89
++ +L Q I+ +A + + E++K QL E + A+H GE + +
Sbjct: 197 LQRWLQQTIKERALLNAHVTQVTESLKQVQL------ERDEYAKHIKGE-----RARWQE 245
Query: 90 YATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGSSPAGSLADAMSQKHLQINQTFE 149
++ E R I I E+ L N + P A++ Q+ +
Sbjct: 246 RMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAK 305
Query: 150 ELRLVTQDTENELK-KLQQTQEYFIIQYQESLRIQAQFGPLAQ-----LSPQERLSRETA 203
LR + E +L+ +++ Q ++ ++ R+Q Q L + + QERL +
Sbjct: 306 HLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNE 365
Query: 204 -LQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQL 261
L+++Q +L+ +R + Q+ R + E+ +K + L+KQ+ + D E WK+ ++L
Sbjct: 366 RLREQQKTLQEQGERLRKQEQRLRKQ-EERLRKEEERLQKQEKRLWDQEERLWKKEERL 423
>gi|38348729 hypothetical protein LOC203238 [Homo sapiens]
Length = 1326
Score = 40.0 bits (92), Expect = 0.008
Identities = 34/133 (25%), Positives = 67/133 (50%), Gaps = 19/133 (14%)
Query: 135 DAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSP 194
DA+ + N+ L + ++ + +++LQQTQE + E ++ AQ S
Sbjct: 608 DALIADLNRANEKIRHLEYICKNKSDTMRELQQTQEDTFTKVAEQIK--------AQESC 659
Query: 195 QERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRK-QQTIILDD--- 250
R +E LQ ++ LE +Q+ AQ Q E+AEK+ + L + K + ++L++
Sbjct: 660 WHRQKKELELQYSELFLE--VQKRAQKFQ----EIAEKNMEKLNHIEKSHEQLVLENSHF 713
Query: 251 -ELIQWKRRQQLA 262
+L+ +R+Q++
Sbjct: 714 KKLLSQTQREQMS 726
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 39.7 bits (91), Expect = 0.011
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 12/130 (9%)
Query: 140 KHLQINQTFEELRLVTQDTENELKK---LQQTQEYFIIQYQESLRIQAQFGPLAQLSPQE 196
K ++ Q E + + E E K+ L++ QE + + QE R + + LA+ +E
Sbjct: 727 KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEE 786
Query: 197 RLSR----ETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDEL 252
L R E AL++++ E Q EA + R E+ +K +LLRKQ ++E
Sbjct: 787 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ-----EEEA 841
Query: 253 IQWKRRQQLA 262
+W R ++ A
Sbjct: 842 AKWAREEEEA 851
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 39.7 bits (91), Expect = 0.011
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 12/130 (9%)
Query: 140 KHLQINQTFEELRLVTQDTENELKK---LQQTQEYFIIQYQESLRIQAQFGPLAQLSPQE 196
K ++ Q E + + E E K+ L++ QE + + QE R + + LA+ +E
Sbjct: 754 KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEE 813
Query: 197 RLSR----ETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDEL 252
L R E AL++++ E Q EA + R E+ +K +LLRKQ ++E
Sbjct: 814 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ-----EEEA 868
Query: 253 IQWKRRQQLA 262
+W R ++ A
Sbjct: 869 AKWAREEEEA 878
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 39.7 bits (91), Expect = 0.011
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 12/130 (9%)
Query: 140 KHLQINQTFEELRLVTQDTENELKK---LQQTQEYFIIQYQESLRIQAQFGPLAQLSPQE 196
K ++ Q E + + E E K+ L++ QE + + QE R + + LA+ +E
Sbjct: 733 KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEE 792
Query: 197 RLSR----ETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDEL 252
L R E AL++++ E Q EA + R E+ +K +LLRKQ ++E
Sbjct: 793 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ-----EEEA 847
Query: 253 IQWKRRQQLA 262
+W R ++ A
Sbjct: 848 AKWAREEEEA 857
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 39.7 bits (91), Expect = 0.011
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 12/130 (9%)
Query: 140 KHLQINQTFEELRLVTQDTENELKK---LQQTQEYFIIQYQESLRIQAQFGPLAQLSPQE 196
K ++ Q E + + E E K+ L++ QE + + QE R + + LA+ +E
Sbjct: 733 KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEE 792
Query: 197 RLSR----ETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDEL 252
L R E AL++++ E Q EA + R E+ +K +LLRKQ ++E
Sbjct: 793 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ-----EEEA 847
Query: 253 IQWKRRQQLA 262
+W R ++ A
Sbjct: 848 AKWAREEEEA 857
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 39.7 bits (91), Expect = 0.011
Identities = 85/370 (22%), Positives = 160/370 (43%), Gaps = 53/370 (14%)
Query: 112 ILYNEQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEY 171
+L ++ V E + + L +++ Q ++ EEL V + ENEL+K Q+ E
Sbjct: 1122 LLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAENELRKQQRNVED 1181
Query: 172 FIIQYQESLRIQAQFGPLAQLSPQERLSRETALQQ-KQVSLEAWLQREA--QTLQQYRVE 228
+Q + Q+ + +E+ + E L++ +Q+++EA +R A + L +R +
Sbjct: 1182 ISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQ 1241
Query: 229 LAEK--HQKTLQLLRKQQTIILDD-ELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLA-- 283
L E ++TL+ K++ + L+D E + K ++L E L +++ + LA
Sbjct: 1242 LEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQ 1301
Query: 284 ------------EIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTST 331
+I + R++I ++ C++ +P + AT ++ L
Sbjct: 1302 KQVAEKQLKEKQKIELEARRKITEIQYTCRENALP-----VCPITQATSCRAVTGLQQEH 1356
Query: 332 FIIEKQPPQVLKTQT-KFAATVRLLVGG--KLNVHMNPPQVKATIISEQQAKSL------ 382
+KQ + LK Q + A R +L +N Q++ T SE++A+ L
Sbjct: 1357 ---DKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKT-SSEEKARLLKDKLDE 1412
Query: 383 -------LKNENTRND-----YSGEILNNCCVMEYHQATGTLSAHFRNMS-LKRIKRSDR 429
LK E R D YS ++ + +Q TG + S LK+IKR+ +
Sbjct: 1413 TNNTLRCLKLELERKDQAEKGYSQQLRE--LGRQLNQTTGKAEEAMQEASDLKKIKRNYQ 1470
Query: 430 RGAESVTEEK 439
ES+ EK
Sbjct: 1471 LELESLNHEK 1480
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 39.7 bits (91), Expect = 0.011
Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 73 EHQVGEDGFLLKIKLGH---YATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGSSP 129
EHQ+ LL K+ A LQ T E ++ +L EQ +VR+ +
Sbjct: 2557 EHQLRRQVELLAYKVEQEKCIAGDLQKTLSE-EQEKANSVQKLLAAEQTVVRDLKSDLCE 2615
Query: 130 AGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPL 189
+ ++ +S+ ++ Q +LR + ENELK Q E + + +Q+Q
Sbjct: 2616 SRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELE---SEQGKGRALQSQLEEE 2672
Query: 190 AQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKT 236
Q AL++ + SL E Q Q R+ +A KH++T
Sbjct: 2673 QLRHLQRESQSAKALEELRASL------ETQRAQSSRLCVALKHEQT 2713
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 39.3 bits (90), Expect = 0.014
Identities = 72/330 (21%), Positives = 137/330 (41%), Gaps = 34/330 (10%)
Query: 6 QAQQLQGEALHQMQALYGQHFPIEVRHYLS--QWIESQAWDSVDLDNPQENIKATQLLEG 63
Q Q Q +H +++ H + R Q ++SQ +L +E++ TQ LE
Sbjct: 1602 QELQAQSSQIHDLES----HSTVLARELQERDQEVKSQREQIEELQRQKEHL--TQDLER 1655
Query: 64 LVQELQKKAEH-QVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVRE 122
QEL + E QV ED + K+ L+ ++ + L R + Q +
Sbjct: 1656 RDQELMLQKERIQVLEDQRTRQTKI------LEEDLEQIKLSLRERGRELTTQRQLMQER 1709
Query: 123 ANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRI 182
A G P S A S +H+++ +E + Q + + +LQ+ ++ Q Q R
Sbjct: 1710 AEEGKGP--SKAQRGSLEHMKLILRDKEKEVECQ--QEHIHELQELKDQLEQQLQGLHRK 1765
Query: 183 QAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRK 242
+ L QE + + LQ+ + E Q L + + LA++ Q+ L ++
Sbjct: 1766 VGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQE 1825
Query: 243 QQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQ 302
QQ +E ++ K +G+L+ ++ + +++Q RR E ++
Sbjct: 1826 QQQAQGQEERVKEK--------ADALQGALEQAHMTLKERHGELQDHKEQARRLE---EE 1874
Query: 303 LPIPG----PVEEMLAEVNATITDIISALV 328
L + G +EE+L ++ A + AL+
Sbjct: 1875 LAVEGRRVQALEEVLGDLRAESREQEKALL 1904
Score = 34.7 bits (78), Expect = 0.35
Identities = 76/395 (19%), Positives = 165/395 (41%), Gaps = 50/395 (12%)
Query: 8 QQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIK-ATQLLEGLVQ 66
+++ A+ + +AL + +EVR +++ D DL + + A +LLE +
Sbjct: 721 EEVLARAVQEKEALVREKAALEVR------LQAVERDRQDLAEQLQGLSSAKELLESSLF 774
Query: 67 ELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMEL--VRCIRHILYNEQRLVREAN 124
E Q++ ++++ G Q+Q + VRC++ L E+ +
Sbjct: 775 EAQQQNS--------VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQER 826
Query: 125 NGSSPAGSLADAMSQKHLQ---------INQTFEELRLVTQDTENELKKLQQTQEYFIIQ 175
+ ++ + A+ + L+ +NQ E+ + EL K ++ E ++
Sbjct: 827 DAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKME 886
Query: 176 YQESLRIQ-AQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQ 234
+ L+ Q + + +ER E+AL Q Q+ E +TL Q + ELA+ Q
Sbjct: 887 LEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQ 946
Query: 235 KTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIR 294
+ L+ LR+ D +Q + Q+ G LQ +L E Q+R +
Sbjct: 947 Q-LERLRQ-------DMKVQKLKEQETTGI------LQTQLQEAQRELKEAARQHRDDLA 992
Query: 295 RAEHLCQQLPIPGPVEEMLAEVNATITDIISALVT---STFIIEKQPPQVLKTQTKFAAT 351
+ L +++ + ++ + D+ S LV S ++E++ + L+ ++
Sbjct: 993 ALQEESSSL-----LQDKM-DLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRI 1046
Query: 352 VRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNE 386
+ L K ++ ++ + + ++ Q+A S+ + E
Sbjct: 1047 QKELEREKASLTLSLMEKEQRLLVLQEADSIRQQE 1081
Score = 30.4 bits (67), Expect = 6.7
Identities = 64/284 (22%), Positives = 105/284 (36%), Gaps = 43/284 (15%)
Query: 53 ENIKATQLLEGLVQELQKKAEHQVGEDGFL-LKIKLGHYATQLQ----NTYDRCPMELVR 107
E + + L G +QEL+K+ E Q L L +K + LQ ++C L
Sbjct: 1432 EREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEH 1491
Query: 108 CIRHILYNEQRL------VREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENE 161
+ EQ+L +RE ++ + + + +Q E R QD
Sbjct: 1492 LPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQD---- 1547
Query: 162 LKKLQQTQEYFIIQYQES-LRIQAQFGPLAQLSPQ---------------ERLSRETALQ 205
LKK T E ++ +E+ +++ Q + +L Q E S+E Q
Sbjct: 1548 LKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQ 1607
Query: 206 QKQVS--------LEAWLQREAQTLQQYRVELAE----KHQKTLQLLRKQQTIILDDELI 253
Q+ L LQ Q ++ R ++ E K T L R+ Q ++L E I
Sbjct: 1608 SSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERI 1667
Query: 254 QWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAE 297
Q Q+ E + S E+ E+ Q + RAE
Sbjct: 1668 QVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAE 1711
>gi|171906567 peripheral benzodiazepine receptor-associated protein
1 isoform b [Homo sapiens]
Length = 1797
Score = 39.3 bits (90), Expect = 0.014
Identities = 52/205 (25%), Positives = 94/205 (45%), Gaps = 15/205 (7%)
Query: 116 EQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQ 175
EQR V++ + S +++ Q+ + + EEL L + +NE +L + +
Sbjct: 274 EQR-VQQLESELSKKRKKCESLEQEARKKQRRCEELELQLRQAQNENARLVEENSRLSGR 332
Query: 176 YQESLRIQAQFGPL-AQLS--PQER---LSRETALQQKQVSLEAWLQREAQTLQQYRVEL 229
E +++ + L QL QER L + LQ K SLE L+ + Q+ R +L
Sbjct: 333 ATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQVLKHMREVAQR-RQQL 391
Query: 230 AEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQN 289
+H++ LR++Q + + Q + +++ G E +LD +Q+ +L E Q
Sbjct: 392 EVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLDSMQARVRELEE---QC 448
Query: 290 RQQIRRAEHLCQQLPI----PGPVE 310
R Q + L Q+L PGP++
Sbjct: 449 RSQTEQFSLLAQELQAFRLHPGPLD 473
>gi|171906559 peripheral benzodiazepine receptor-associated protein
1 isoform a [Homo sapiens]
Length = 1857
Score = 39.3 bits (90), Expect = 0.014
Identities = 52/205 (25%), Positives = 94/205 (45%), Gaps = 15/205 (7%)
Query: 116 EQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQ 175
EQR V++ + S +++ Q+ + + EEL L + +NE +L + +
Sbjct: 334 EQR-VQQLESELSKKRKKCESLEQEARKKQRRCEELELQLRQAQNENARLVEENSRLSGR 392
Query: 176 YQESLRIQAQFGPL-AQLS--PQER---LSRETALQQKQVSLEAWLQREAQTLQQYRVEL 229
E +++ + L QL QER L + LQ K SLE L+ + Q+ R +L
Sbjct: 393 ATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQVLKHMREVAQR-RQQL 451
Query: 230 AEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQN 289
+H++ LR++Q + + Q + +++ G E +LD +Q+ +L E Q
Sbjct: 452 EVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLDSMQARVRELEE---QC 508
Query: 290 RQQIRRAEHLCQQLPI----PGPVE 310
R Q + L Q+L PGP++
Sbjct: 509 RSQTEQFSLLAQELQAFRLHPGPLD 533
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 38.9 bits (89), Expect = 0.019
Identities = 47/217 (21%), Positives = 95/217 (43%), Gaps = 19/217 (8%)
Query: 89 HYATQLQNTYDRCPMELVRCIRHILYNEQRLVR-EANNGSSPAGSLADAMSQKHLQINQT 147
++ + + +D CP +LV + YN +++ R E + + + + + K L+
Sbjct: 330 YFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENR 389
Query: 148 FEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALQQK 207
+ R+ T + + ++ + Q+ +E ++I+ + ++ Q L + R+ QQ+
Sbjct: 390 LLKQRIETLE-KGQVTRAQEAEENYVIKRELAVVRQQCSSAAEDLQKAQSTIRQLQEQQE 448
Query: 208 QVSL-EAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGG 266
L E ++ L+Q R+ + +TL LR+ Q +LD E KR L
Sbjct: 449 NPRLTEDFVSHLETELEQSRL----RETETLGALREMQDKVLDME----KRNSSL----- 495
Query: 267 PPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQL 303
P E ++ LQ E+L + + Q + L QL
Sbjct: 496 PDENNVAQLQ---EELKALKVREGQAVASTRELKLQL 529
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,798,654
Number of Sequences: 37866
Number of extensions: 1317655
Number of successful extensions: 4924
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 4363
Number of HSP's gapped (non-prelim): 532
length of query: 787
length of database: 18,247,518
effective HSP length: 110
effective length of query: 677
effective length of database: 14,082,258
effective search space: 9533688666
effective search space used: 9533688666
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.