Search of human proteins with 214831008

Search of human proteins with 214831008

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
isoform 2 [Homo sapiens]
         (195 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ...   390   e-109
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is...   355   2e-98
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [...    73   1e-13
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14...    70   1e-12
gi|149588599 membrane-spanning 4-domains, subfamily A, member 15...    69   3e-12
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i...    69   3e-12
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i...    69   3e-12
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ...    67   1e-11
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i...    60   9e-10
gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i...    59   3e-09
gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i...    59   3e-09
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A...    58   4e-09
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A...    58   4e-09
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A...    58   4e-09
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14...    54   6e-08
gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ...    52   4e-07
gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ...    52   4e-07
gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ...    52   4e-07
gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ...    51   7e-07
gi|167466260 membrane-spanning 4-domains, subfamily A, member 10...    47   1e-05
gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ...    44   9e-05
gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ...    44   9e-05
gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ...    44   9e-05
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [...    44   9e-05
gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [...    44   1e-04
gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [...    44   1e-04
gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]     32   0.26 
gi|46249347 membrane-spanning 4-domains, subfamily A, member 7 i...    32   0.34 
gi|46249359 membrane-spanning 4-domains, subfamily A, member 7 i...    32   0.34 
gi|239046743 Nedd4 family interacting protein 2 isoform 2 [Homo ...    28   3.8  

>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
           isoform 2 [Homo sapiens]
          Length = 195

 Score =  390 bits (1002), Expect = e-109
 Identities = 195/195 (100%), Positives = 195/195 (100%)

Query: 1   MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF 60
           MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
Sbjct: 1   MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF 60

Query: 61  LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER 120
           LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER
Sbjct: 61  LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER 120

Query: 121 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTV 180
           RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTV
Sbjct: 121 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTV 180

Query: 181 CIFFCVGRLRFWVLM 195
           CIFFCVGRLRFWVLM
Sbjct: 181 CIFFCVGRLRFWVLM 195


>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
           isoform 1 [Homo sapiens]
          Length = 244

 Score =  355 bits (910), Expect = 2e-98
 Identities = 179/179 (100%), Positives = 179/179 (100%)

Query: 1   MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF 60
           MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF
Sbjct: 1   MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEF 60

Query: 61  LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER 120
           LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER
Sbjct: 61  LGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISER 120

Query: 121 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFST 179
           RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFST
Sbjct: 121 RNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFST 179


>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
           [Homo sapiens]
          Length = 267

 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 38/110 (34%), Positives = 64/110 (58%), Gaps = 1/110 (0%)

Query: 44  SPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCSV-LDISHIEGDIFSSFKAGYPF 102
           +P + T +   K+E + LGV QI+  ++ + FG V+C +      + G   ++   GYPF
Sbjct: 74  NPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGGYPF 133

Query: 103 WGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINL 152
           WG + F ISG LS+ + +  +  LV+GSLG N  SSI    G+ +L++++
Sbjct: 134 WGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDM 183


>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
           isoform 1 [Homo sapiens]
          Length = 679

 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 51/162 (31%), Positives = 75/162 (46%), Gaps = 21/162 (12%)

Query: 22  AFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCS 81
           A  V+ I P E     +L +    P  + L  LK E   LG TQIL A+I + FGT+   
Sbjct: 10  ATHVITIKPNET----VLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFA- 64

Query: 82  VLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAG 141
            L+       +      GYPFWGA+ F ++G L++  ++  +  L +G  G N  SS+  
Sbjct: 65  -LNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKK--SKLLGQGVTGMNVISSLVA 121

Query: 142 GTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTVCIF 183
            TGIT  I++ +    Y             C M SF  +C+F
Sbjct: 122 ITGITFTILSYRHQDKY-------------CQMPSFEEICVF 150


>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 50/143 (34%), Positives = 68/143 (47%), Gaps = 15/143 (10%)

Query: 13  LPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMIC 72
           LP      P     E  P    + R  +     P+ T+LT    E + LG  QIL  +I 
Sbjct: 29  LPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLT---GEPKVLGTVQILIGLIH 85

Query: 73  LCFGTVVCSV----LDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVR 128
           L FG+V+  V    + I  IEG        G PFWG   F ISG LS+ +E+ + + LVR
Sbjct: 86  LGFGSVLLMVRRGHVGIFFIEG--------GVPFWGGACFIISGSLSVAAEKNHTSCLVR 137

Query: 129 GSLGANTASSIAGGTGITILIIN 151
            SLG N  S +A   G  IL+++
Sbjct: 138 SSLGTNILSVMAAFAGTAILLMD 160


>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
           isoform a [Homo sapiens]
          Length = 220

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 47/110 (42%), Positives = 59/110 (53%), Gaps = 8/110 (7%)

Query: 54  LKKEQEFLGVTQILTAMICLCFG-TVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISG 112
           LK E + LGV QILTA++ L  G T++C     S+  G    S   GY  WG++ F ISG
Sbjct: 40  LKGEPKVLGVVQILTALMSLSMGITMMCMA---SNTYGSNPISVYIGYTIWGSVMFIISG 96

Query: 113 MLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIH 162
            LSI +  R    LVRGSLG N  SS+   +GI I       SLA+   H
Sbjct: 97  SLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTF----SLAFYSFH 142


>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
           isoform b [Homo sapiens]
          Length = 239

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 47/110 (42%), Positives = 59/110 (53%), Gaps = 8/110 (7%)

Query: 54  LKKEQEFLGVTQILTAMICLCFG-TVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISG 112
           LK E + LGV QILTA++ L  G T++C     S+  G    S   GY  WG++ F ISG
Sbjct: 59  LKGEPKVLGVVQILTALMSLSMGITMMCMA---SNTYGSNPISVYIGYTIWGSVMFIISG 115

Query: 113 MLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIH 162
            LSI +  R    LVRGSLG N  SS+   +GI I       SLA+   H
Sbjct: 116 SLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTF----SLAFYSFH 161


>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
           [Homo sapiens]
          Length = 250

 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 16/142 (11%)

Query: 13  LPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMIC 72
           +P  P+S P   ++  +P       L+ + +  P+   L    KE + LG  QI+  +  
Sbjct: 33  VPLYPNSQPQVHLVPGNPPS-----LVSNVNGQPVQKAL----KEGKTLGAIQIIIGLAH 83

Query: 73  LCFGTVVCSVLDISHIEGDIFS-SFKAGYPFWGAIFFSISGMLSIISERRNATY-LVRGS 130
           +  G+++ +VL      G+  S SF  G+PFWG ++F ISG LS+ +E +  +Y L+ GS
Sbjct: 84  IGLGSIMATVL-----VGEYLSISFYGGFPFWGGLWFIISGSLSVAAENQPYSYCLLSGS 138

Query: 131 LGANTASSIAGGTGITILIINL 152
           LG N  S+I    G+ + I +L
Sbjct: 139 LGLNIVSAICSAVGVILFITDL 160


>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
           isoform a [Homo sapiens]
          Length = 214

 Score = 60.5 bits (145), Expect = 9e-10
 Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 8/154 (5%)

Query: 27  EISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCSVLDIS 86
           E  P+E+++        SP         K + + LG  QIL A + L  G  + S+    
Sbjct: 23  EAGPEELNTSVYQPIDGSPDYQ------KAKLQVLGAIQILNAAMILALGVFLGSLQYPY 76

Query: 87  HIEGDIFS-SFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGI 145
           H +   F  +F  GYP WGA+FF  SG LS+++  +     ++ S G N AS+     G 
Sbjct: 77  HFQKHFFFFTFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGT 136

Query: 146 TILIINLKKSLAYIH-IHSCQKFFETKCFMASFS 178
             L +N+  ++  +   HS  +  +   +M S S
Sbjct: 137 AFLSLNIAVNIQSLRSCHSSSESPDLCNYMGSIS 170


>gi|11139299 membrane-spanning 4-domains, subfamily A, member 7
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 33/95 (34%), Positives = 49/95 (51%)

Query: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113
           L  E   LG  QIL  ++    G ++      SH    I ++  +GYPF GA+ F I+G 
Sbjct: 41  LPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGS 100

Query: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITIL 148
           LSIIS +++       SL +N  SS+  G G+ +L
Sbjct: 101 LSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135


>gi|46249357 membrane-spanning 4-domains, subfamily A, member 7
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 33/95 (34%), Positives = 49/95 (51%)

Query: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113
           L  E   LG  QIL  ++    G ++      SH    I ++  +GYPF GA+ F I+G 
Sbjct: 41  LPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPAISTTLMSGYPFLGALCFGITGS 100

Query: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITIL 148
           LSIIS +++       SL +N  SS+  G G+ +L
Sbjct: 101 LSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135


>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 1 [Homo sapiens]
          Length = 243

 Score = 58.2 bits (139), Expect = 4e-09
 Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 55  KKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGML 114
           K++ + LGV +IL A++ L  G ++  V   S+ E  IF      Y  WG++ F IS  L
Sbjct: 64  KRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIF--VYVAYTIWGSVMFIISVSL 121

Query: 115 SIISERRNATYLVRGSLGANTASSIAGGTGITILIINL 152
           S+ +  R    LV GSLG N  SS+   +GI I  I+L
Sbjct: 122 SVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISL 159


>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 3 [Homo sapiens]
          Length = 243

 Score = 58.2 bits (139), Expect = 4e-09
 Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 55  KKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGML 114
           K++ + LGV +IL A++ L  G ++  V   S+ E  IF      Y  WG++ F IS  L
Sbjct: 64  KRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIF--VYVAYTIWGSVMFIISVSL 121

Query: 115 SIISERRNATYLVRGSLGANTASSIAGGTGITILIINL 152
           S+ +  R    LV GSLG N  SS+   +GI I  I+L
Sbjct: 122 SVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISL 159


>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 3 [Homo sapiens]
          Length = 243

 Score = 58.2 bits (139), Expect = 4e-09
 Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 55  KKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGML 114
           K++ + LGV +IL A++ L  G ++  V   S+ E  IF      Y  WG++ F IS  L
Sbjct: 64  KRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIF--VYVAYTIWGSVMFIISVSL 121

Query: 115 SIISERRNATYLVRGSLGANTASSIAGGTGITILIINL 152
           S+ +  R    LV GSLG N  SS+   +GI I  I+L
Sbjct: 122 SVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISL 159


>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
           isoform 2 [Homo sapiens]
          Length = 662

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 47/162 (29%), Positives = 65/162 (40%), Gaps = 38/162 (23%)

Query: 22  AFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCS 81
           A  V+ I P E     +L +    P  + L  LK E   LG TQIL A+I + FGT+   
Sbjct: 10  ATHVITIKPNET----VLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIF-- 63

Query: 82  VLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAG 141
            L+       +      GYPFWGA+                   + +G  G N  SS+  
Sbjct: 64  ALNYIGFSQRLPLVVLTGYPFWGAL-------------------IGQGVTGMNVISSLVA 104

Query: 142 GTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTVCIF 183
            TGIT  I++ +    Y             C M SF  +C+F
Sbjct: 105 ITGITFTILSYRHQDKY-------------CQMPSFEEICVF 133


>gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 2 [Homo sapiens]
          Length = 225

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 32/97 (32%), Positives = 47/97 (48%)

Query: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113
           L  E + +G  QIL  M+ L  G ++ S     +      +   + YPF G  FF ISG 
Sbjct: 41  LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100

Query: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII 150
           LSI +E+R    LV  SL  +  S+++   G  IL +
Sbjct: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137


>gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 3 [Homo sapiens]
          Length = 178

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 32/97 (32%), Positives = 47/97 (48%)

Query: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113
           L  E + +G  QIL  M+ L  G ++ S     +      +   + YPF G  FF ISG 
Sbjct: 41  LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100

Query: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII 150
           LSI +E+R    LV  SL  +  S+++   G  IL +
Sbjct: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137


>gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 1 [Homo sapiens]
          Length = 248

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 32/97 (32%), Positives = 47/97 (48%)

Query: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113
           L  E + +G  QIL  M+ L  G ++ S     +      +   + YPF G  FF ISG 
Sbjct: 41  LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100

Query: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII 150
           LSI +E+R    LV  SL  +  S+++   G  IL +
Sbjct: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137


>gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
           isoform 2 [Homo sapiens]
          Length = 147

 Score = 50.8 bits (120), Expect = 7e-07
 Identities = 24/55 (43%), Positives = 34/55 (61%)

Query: 97  KAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIIN 151
           + G PFWG   F ISG LS+ +E+ + + LVR SLG N  S +A   G  IL+++
Sbjct: 13  EGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD 67


>gi|167466260 membrane-spanning 4-domains, subfamily A, member 10
           [Homo sapiens]
          Length = 267

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 9/120 (7%)

Query: 29  SPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHI 88
           +PQ  +  +LL            ++LK+    LG   I  A++ L FG  + S++   H+
Sbjct: 32  APQNTTQPKLLAPHQHEKSQKKSSLLKE----LGAFHITIALLHLVFGGYLASIVKNLHL 87

Query: 89  EGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITIL 148
                   K+ YPFWGA  F ISG+L+I  +  + TYL    L  N  S     +G+ ++
Sbjct: 88  V-----VLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142


>gi|169202868 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 2/71 (2%)

Query: 93  FSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINL 152
           F ++ +GYP WG + + +SG LS+ + +  +  +V  S+  N  S++    GI I+I +L
Sbjct: 174 FVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDL 233

Query: 153 KKSLAYIHIHS 163
             SL Y+  +S
Sbjct: 234 --SLYYVTTYS 242


>gi|169203526 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 2/71 (2%)

Query: 93  FSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINL 152
           F ++ +GYP WG + + +SG LS+ + +  +  +V  S+  N  S++    GI I+I +L
Sbjct: 174 FVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDL 233

Query: 153 KKSLAYIHIHS 163
             SL Y+  +S
Sbjct: 234 --SLYYVTTYS 242


>gi|169202217 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 2/71 (2%)

Query: 93  FSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINL 152
           F ++ +GYP WG + + +SG LS+ + +  +  +V  S+  N  S++    GI I+I +L
Sbjct: 174 FVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDL 233

Query: 153 KKSLAYIHIHS 163
             SL Y+  +S
Sbjct: 234 --SLYYVTTYS 242


>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
           [Homo sapiens]
          Length = 200

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 39/152 (25%), Positives = 63/152 (41%), Gaps = 6/152 (3%)

Query: 18  SSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKK----EQEFLGVTQILTAMICL 73
           SS     V  + P E+++     +  S    +  + L+K    + + LG  QIL  ++  
Sbjct: 3   SSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTF 62

Query: 74  CFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGA 133
            FG +    L   +        F +GYPFWG++ F  SG   I  +R+    L+  S   
Sbjct: 63  SFGVIFLFTLLKPYPRFPFI--FLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIM 120

Query: 134 NTASSIAGGTGITILIINLKKSLAYIHIHSCQ 165
           N  S++    GI +L         YI  +S Q
Sbjct: 121 NFLSALGAIAGIILLTFGFILDQNYICGYSHQ 152


>gi|23110987 membrane-spanning 4-domains, subfamily A, member 1
           [Homo sapiens]
          Length = 297

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/154 (24%), Positives = 66/154 (42%), Gaps = 27/154 (17%)

Query: 30  PQEVSSGRLLKSASSPPLHTWLTVL--------KKEQEFLGVTQILTAMICLCFGTVVCS 81
           P E   G +   +   PL   ++ L         +E + LG  QI+  +  +  G ++  
Sbjct: 13  PAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLM- 71

Query: 82  VLDISHIEGDIFSSF--KAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSI 139
                 I   I++       YP WG I + ISG L   +E+ +   LV+G +  N+ S  
Sbjct: 72  ------IPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLF 125

Query: 140 AGGTGITIL---IINLK-------KSLAYIHIHS 163
           A  +G+ +    I+N+K       +SL +I  H+
Sbjct: 126 AAISGMILSIMDILNIKISHFLKMESLNFIRAHT 159


>gi|23110989 membrane-spanning 4-domains, subfamily A, member 1
           [Homo sapiens]
          Length = 297

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/154 (24%), Positives = 66/154 (42%), Gaps = 27/154 (17%)

Query: 30  PQEVSSGRLLKSASSPPLHTWLTVL--------KKEQEFLGVTQILTAMICLCFGTVVCS 81
           P E   G +   +   PL   ++ L         +E + LG  QI+  +  +  G ++  
Sbjct: 13  PAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLM- 71

Query: 82  VLDISHIEGDIFSSF--KAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSI 139
                 I   I++       YP WG I + ISG L   +E+ +   LV+G +  N+ S  
Sbjct: 72  ------IPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLF 125

Query: 140 AGGTGITIL---IINLK-------KSLAYIHIHS 163
           A  +G+ +    I+N+K       +SL +I  H+
Sbjct: 126 AAISGMILSIMDILNIKISHFLKMESLNFIRAHT 159


>gi|38146116 hypothetical protein LOC10712 isoform a [Homo sapiens]
          Length = 668

 Score = 32.3 bits (72), Expect = 0.26
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 14/94 (14%)

Query: 40  KSASSPPLHTWLTVLKKEQEFL------GVTQILTAMICLCFGTVVCSVLDISHIEGDIF 93
           +S +S P    LT L+  + +L      G+ Q+L  ++ + F  V  SV           
Sbjct: 10  RSLTSRPSTRGLTHLRLHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTE------- 62

Query: 94  SSFKAGYPFWGAIFFSISGMLSIISERRNATYLV 127
            S K   P W     + SG++ I+S +R  T ++
Sbjct: 63  -SIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVI 95


>gi|46249347 membrane-spanning 4-domains, subfamily A, member 7
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 32.0 bits (71), Expect = 0.34
 Identities = 16/41 (39%), Positives = 24/41 (58%)

Query: 108 FSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITIL 148
           F I+G LSIIS +++       SL +N  SS+  G G+ +L
Sbjct: 50  FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 90


>gi|46249359 membrane-spanning 4-domains, subfamily A, member 7
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 32.0 bits (71), Expect = 0.34
 Identities = 16/41 (39%), Positives = 24/41 (58%)

Query: 108 FSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITIL 148
           F I+G LSIIS +++       SL +N  SS+  G G+ +L
Sbjct: 50  FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 90


>gi|239046743 Nedd4 family interacting protein 2 isoform 2 [Homo
           sapiens]
          Length = 316

 Score = 28.5 bits (62), Expect = 3.8
 Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 4/50 (8%)

Query: 4   ESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTV 53
           E +   + A+ Q P+S PA +++    Q  SS   L++ SSPP ++ +TV
Sbjct: 111 EEDNSESSAIEQPPTSNPAPQIV----QAASSAPALETDSSPPPYSSITV 156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.137    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,994,161
Number of Sequences: 37866
Number of extensions: 271531
Number of successful extensions: 947
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 906
Number of HSP's gapped (non-prelim): 36
length of query: 195
length of database: 18,247,518
effective HSP length: 97
effective length of query: 98
effective length of database: 14,574,516
effective search space: 1428302568
effective search space used: 1428302568
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.