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Search of human proteins with 213972568
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|213972568 dachshund 2 isoform c [Homo sapiens]
(432 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|213972568 dachshund 2 isoform c [Homo sapiens] 849 0.0
gi|16876441 dachshund 2 isoform a [Homo sapiens] 849 0.0
gi|213972566 dachshund 2 isoform b [Homo sapiens] 800 0.0
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 395 e-110
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 205 6e-53
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 203 2e-52
gi|56549694 enabled homolog isoform a [Homo sapiens] 52 1e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 52 1e-06
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 51 2e-06
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 51 2e-06
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 51 2e-06
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens] 50 4e-06
gi|148746195 trichohyalin [Homo sapiens] 48 2e-05
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 47 3e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 47 4e-05
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 47 4e-05
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 47 4e-05
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 47 4e-05
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 47 4e-05
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 45 1e-04
gi|67763814 death-inducing-protein [Homo sapiens] 44 3e-04
gi|62244004 modulator of estrogen induced transcription isoform ... 43 5e-04
gi|63176611 modulator of estrogen induced transcription isoform ... 43 5e-04
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 43 5e-04
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof... 43 5e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 43 5e-04
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 42 0.001
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 42 0.001
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens] 42 0.001
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 42 0.001
>gi|213972568 dachshund 2 isoform c [Homo sapiens]
Length = 432
Score = 849 bits (2193), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ 60
MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ
Sbjct: 1 MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ 60
Query: 61 KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL 120
KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL
Sbjct: 61 KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL 120
Query: 121 AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA 180
AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA
Sbjct: 121 AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA 180
Query: 181 NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD 240
NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD
Sbjct: 181 NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD 240
Query: 241 HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK 300
HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK
Sbjct: 241 HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK 300
Query: 301 VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 360
VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR
Sbjct: 301 VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 360
Query: 361 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY 420
KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY
Sbjct: 361 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY 420
Query: 421 YCLEMAQQLYSA 432
YCLEMAQQLYSA
Sbjct: 421 YCLEMAQQLYSA 432
>gi|16876441 dachshund 2 isoform a [Homo sapiens]
Length = 599
Score = 849 bits (2193), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ 60
MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ
Sbjct: 168 MTRKQAVNSSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQ 227
Query: 61 KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL 120
KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL
Sbjct: 228 KMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAAL 287
Query: 121 AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA 180
AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA
Sbjct: 288 AGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIA 347
Query: 181 NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD 240
NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD
Sbjct: 348 NMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMD 407
Query: 241 HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK 300
HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK
Sbjct: 408 HHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLK 467
Query: 301 VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 360
VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR
Sbjct: 468 VALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 527
Query: 361 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY 420
KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY
Sbjct: 528 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGGNY 587
Query: 421 YCLEMAQQLYSA 432
YCLEMAQQLYSA
Sbjct: 588 YCLEMAQQLYSA 599
>gi|213972566 dachshund 2 isoform b [Homo sapiens]
Length = 571
Score = 800 bits (2066), Expect = 0.0
Identities = 408/408 (100%), Positives = 408/408 (100%)
Query: 9 SSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMN 68
SSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMN
Sbjct: 163 SSRPGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMN 222
Query: 69 TLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGG 128
TLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGG
Sbjct: 223 TLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIGG 282
Query: 129 APTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQI 188
APTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQI
Sbjct: 283 APTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQI 342
Query: 189 HSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEE 248
HSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEE
Sbjct: 343 HSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEE 402
Query: 249 VPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARI 308
VPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARI
Sbjct: 403 VPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARI 462
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF
Sbjct: 463 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 522
Query: 369 ESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 416
ESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ
Sbjct: 523 ESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQ 570
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 395 bits (1014), Expect = e-110
Identities = 233/471 (49%), Positives = 289/471 (61%), Gaps = 112/471 (23%)
Query: 9 SSRPGRPPKRSLGVLQ-ENARLLTHAVPGLLSPGLITPTGITAAA----------MAEAM 57
SSRPGRPPKR+ V EN+ ++ H+VPGL+SPG+I PTG+TAAA +AEAM
Sbjct: 283 SSRPGRPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAM 342
Query: 58 KLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAH 117
K++K+KL AM+ + +Q+G +SE D+NS+ G
Sbjct: 343 KVKKIKLEAMSNYHASNNQHGADSENGDMNSSVG-------------------------- 376
Query: 118 AALAGQPGIGGAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLN 177
L+LPFMMMPHPL+PVSLPPASV MAM+QMNHL+
Sbjct: 377 ---------------------------LELPFMMMPHPLIPVSLPPASVTMAMSQMNHLS 409
Query: 178 TIANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPS 237
TIANMAAAAQ+ SP SR TSVIKER+P+SPSPAPSLEE RPGS SSH SSSVSSSP+
Sbjct: 410 TIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPA 469
Query: 238 Q-----------------------------------------MDHHLERM----EEVPVQ 252
+ M H +RM +E P+
Sbjct: 470 RTESSSDRIPVHQNGLSMNQMLMGLSPNVLPGPKEGDLAGHDMGHESKRMHIEKDETPLS 529
Query: 253 IPIMKSPLDKIQLTP-GQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEK 311
P + LDK+ LT GQ LP GFP PF+F D LSS+ETLLTNIQGLLKVA+DNAR QEK
Sbjct: 530 TPTARDSLDKLSLTGHGQPLPPGFPSPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEK 589
Query: 312 QIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESK 371
Q+Q EK EL+++ RERE+RE LE+QLA+E ++R +QKRLKKEKK KRKLQEALEFE+K
Sbjct: 590 QVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFETK 649
Query: 372 RREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDS-AAMQGGNYY 421
RREQ EQ LKQA ++DS LR+L D+ P+IE + +G D+ +Q G Y
Sbjct: 650 RREQAEQTLKQAASTDS-LRVLNDSLTPEIEADRSGGRTDAERTIQDGRLY 699
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 205 bits (522), Expect = 6e-53
Identities = 110/202 (54%), Positives = 145/202 (71%), Gaps = 3/202 (1%)
Query: 222 SQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTP-GQALPAGFPGPFI 280
+ ++ H S++ + S+ ++E P+ P + LDK+ LT GQ LP GFP PF+
Sbjct: 351 AMSNYHASNNQHGADSENGDMNSSVDETPLSTPTARDSLDKLSLTGHGQPLPPGFPSPFL 410
Query: 281 FADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAV 340
F D LSS+ETLLTNIQGLLKVA+DNAR QEKQ+Q EK EL+++ RERE+RE LE+QLA+
Sbjct: 411 FPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAM 470
Query: 341 ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPD 400
E ++R +QKRLKKEKK KRKLQEALEFE+KRREQ EQ LKQA ++DS LR+L D+ P+
Sbjct: 471 EQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDS-LRVLNDSLTPE 529
Query: 401 IEIENNGTPHDS-AAMQGGNYY 421
IE + +G D+ +Q G Y
Sbjct: 530 IEADRSGGRTDAERTIQDGRLY 551
Score = 90.1 bits (222), Expect = 3e-18
Identities = 54/136 (39%), Positives = 80/136 (58%), Gaps = 24/136 (17%)
Query: 9 SSRPGRPPKRSLGVLQ-ENARLLTHAVPGLLSPGLITPTGITA----------AAMAEAM 57
SSRPGRPPKR+ V EN+ ++ H+VPGL+SPG+I PTG+TA AA+AEAM
Sbjct: 283 SSRPGRPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAM 342
Query: 58 KLQKMKLMAMNTLQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAH 117
K++K+KL AM+ + +Q+G +SE D+NS+ ++P + P + +
Sbjct: 343 KVKKIKLEAMSNYHASNNQHGADSENGDMNSSVD-----------ETPLSTPTARDSLDK 391
Query: 118 AALA--GQPGIGGAPT 131
+L GQP G P+
Sbjct: 392 LSLTGHGQPLPPGFPS 407
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 203 bits (517), Expect = 2e-52
Identities = 117/211 (55%), Positives = 146/211 (69%), Gaps = 9/211 (4%)
Query: 219 RPGSQTSSHTSSSVS-----SSPSQMDHHL-ERMEEVPVQIPIMKSPLDKIQLTP-GQAL 271
RP +T S TS S S P M + +E P+ P + LDK+ LT GQ L
Sbjct: 288 RPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTDETPLSTPTARDSLDKLSLTGHGQPL 347
Query: 272 PAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIR 331
P GFP PF+F D LSS+ETLLTNIQGLLKVA+DNAR QEKQ+Q EK EL+++ RERE+R
Sbjct: 348 PPGFPSPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEKTELKMDFLRERELR 407
Query: 332 ENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLR 391
E LE+QLA+E ++R +QKRLKKEKK KRKLQEALEFE+KRREQ EQ LKQA ++DS LR
Sbjct: 408 ETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDS-LR 466
Query: 392 MLKDTGIPDIEIENNGTPHDS-AAMQGGNYY 421
+L D+ P+IE + +G D+ +Q G Y
Sbjct: 467 VLNDSLTPEIEADRSGGRTDAERTIQDGRLY 497
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/58 (50%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 9 SSRPGRPPKRSLGVLQ-ENARLLTHAVPGLLSPGLITPTGITAAAMAEAM-KLQKMKL 64
SSRPGRPPKR+ V EN+ ++ H+VPGL+SPG+I PT T + A L K+ L
Sbjct: 283 SSRPGRPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTDETPLSTPTARDSLDKLSL 340
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 52.0 bits (123), Expect = 1e-06
Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Query: 303 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK--KTKR 360
L+ R++ ++++QE+ E + ERE +E LERQ +E Q R Q+RL +E+ + +R
Sbjct: 176 LERERLERERLEQEQLERERQ---ERERQERLERQERLERQERLERQERLDRERQERQER 232
Query: 361 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGG 418
+ E LE E + RE+ EQ ++ + R+ +E N DS+A + G
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG 290
Score = 36.6 bits (83), Expect = 0.045
Identities = 32/128 (25%), Positives = 65/128 (50%), Gaps = 16/128 (12%)
Query: 303 LDNARIQEKQIQQEKKEL----------RLELYREREIRENLERQLAVELQSRTTMQKRL 352
L+ R++++Q+++E++E RLE E +E L+R+ E Q R ++ RL
Sbjct: 181 LERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRE-RQERQERERLE-RL 238
Query: 353 KKEKKTKRKLQEALE---FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTP 409
++E++ +R+ QE LE E +R ++ A A+ +L D+ + ++ P
Sbjct: 239 ERERQ-ERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQP 297
Query: 410 HDSAAMQG 417
++ + QG
Sbjct: 298 AETPSQQG 305
Score = 32.0 bits (71), Expect = 1.1
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Query: 312 QIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKTKRKL------QE 364
Q+Q + LE+ R + + +++L E R M++ RL++E+ + +L QE
Sbjct: 130 QVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQE 189
Query: 365 ALEFESKRREQVEQALKQ 382
LE E + RE+ E+ +Q
Sbjct: 190 QLERERQERERQERLERQ 207
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 52.0 bits (123), Expect = 1e-06
Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Query: 303 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK--KTKR 360
L+ R++ ++++QE+ E + ERE +E LERQ +E Q R Q+RL +E+ + +R
Sbjct: 176 LERERLERERLEQEQLERERQ---ERERQERLERQERLERQERLERQERLDRERQERQER 232
Query: 361 KLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQGG 418
+ E LE E + RE+ EQ ++ + R+ +E N DS+A + G
Sbjct: 233 ERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPG 290
Score = 36.6 bits (83), Expect = 0.045
Identities = 32/128 (25%), Positives = 65/128 (50%), Gaps = 16/128 (12%)
Query: 303 LDNARIQEKQIQQEKKEL----------RLELYREREIRENLERQLAVELQSRTTMQKRL 352
L+ R++++Q+++E++E RLE E +E L+R+ E Q R ++ RL
Sbjct: 181 LERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRE-RQERQERERLE-RL 238
Query: 353 KKEKKTKRKLQEALE---FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTP 409
++E++ +R+ QE LE E +R ++ A A+ +L D+ + ++ P
Sbjct: 239 ERERQ-ERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQP 297
Query: 410 HDSAAMQG 417
++ + QG
Sbjct: 298 AETPSQQG 305
Score = 32.0 bits (71), Expect = 1.1
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 7/78 (8%)
Query: 312 QIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKTKRKL------QE 364
Q+Q + LE+ R + + +++L E R M++ RL++E+ + +L QE
Sbjct: 130 QVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQE 189
Query: 365 ALEFESKRREQVEQALKQ 382
LE E + RE+ E+ +Q
Sbjct: 190 QLERERQERERQERLERQ 207
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.8 bits (120), Expect = 2e-06
Identities = 65/314 (20%), Positives = 131/314 (41%), Gaps = 63/314 (20%)
Query: 134 PLQQNHLLTNRLDLPFMMMPH--PLLPVS-LPPASVAM------------AMNQMNHLNT 178
P +QN ++ LD + + P P + PPAS+ + M +N
Sbjct: 321 PRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTP 380
Query: 179 IANMAAAAQIHSPLSRAGTSVIK-ERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPS 237
+ +AA+ SP+ + S+ +I + PA L E HR S++++H S S
Sbjct: 381 VEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQS--- 437
Query: 238 QMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQG 297
G+ +P P +F+ +L + I
Sbjct: 438 ------------------------------GKVIPDRSTKPVVFSPTLMLTDEEKARIHA 467
Query: 298 LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKE-- 355
+ ++ + QEK++++ ++E + E R+ E + +++ E T Q++ K+E
Sbjct: 468 ETALLMEKNK-QEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEME 526
Query: 356 -KKTKRKLQEALEFESKRREQV----EQALKQATTSDSGLRMLKDTG----IPDIEIENN 406
K++++ +E E +KR +++ Q+ + TSD+ + ++D G P+I+ ++
Sbjct: 527 KKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDA-KKSVEDRGKRCPTPEIQKKST 585
Query: 407 G-TPHDSAAMQGGN 419
G PH S G+
Sbjct: 586 GDVPHTSVTGDSGS 599
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.8 bits (120), Expect = 2e-06
Identities = 65/314 (20%), Positives = 131/314 (41%), Gaps = 63/314 (20%)
Query: 134 PLQQNHLLTNRLDLPFMMMPH--PLLPVS-LPPASVAM------------AMNQMNHLNT 178
P +QN ++ LD + + P P + PPAS+ + M +N
Sbjct: 321 PRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTP 380
Query: 179 IANMAAAAQIHSPLSRAGTSVIK-ERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPS 237
+ +AA+ SP+ + S+ +I + PA L E HR S++++H S S
Sbjct: 381 VEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQS--- 437
Query: 238 QMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQG 297
G+ +P P +F+ +L + I
Sbjct: 438 ------------------------------GKVIPDRSTKPVVFSPTLMLTDEEKARIHA 467
Query: 298 LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKE-- 355
+ ++ + QEK++++ ++E + E R+ E + +++ E T Q++ K+E
Sbjct: 468 ETALLMEKNK-QEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEME 526
Query: 356 -KKTKRKLQEALEFESKRREQV----EQALKQATTSDSGLRMLKDTG----IPDIEIENN 406
K++++ +E E +KR +++ Q+ + TSD+ + ++D G P+I+ ++
Sbjct: 527 KKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDA-KKSVEDRGKRCPTPEIQKKST 585
Query: 407 G-TPHDSAAMQGGN 419
G PH S G+
Sbjct: 586 GDVPHTSVTGDSGS 599
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 50.8 bits (120), Expect = 2e-06
Identities = 65/314 (20%), Positives = 131/314 (41%), Gaps = 63/314 (20%)
Query: 134 PLQQNHLLTNRLDLPFMMMPH--PLLPVS-LPPASVAM------------AMNQMNHLNT 178
P +QN ++ LD + + P P + PPAS+ + M +N
Sbjct: 321 PRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDENIELISGQNERMGPLNISTP 380
Query: 179 IANMAAAAQIHSPLSRAGTSVIK-ERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPS 237
+ +AA+ SP+ + S+ +I + PA L E HR S++++H S S
Sbjct: 381 VEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEEHRIKSESTNHEQQSPQS--- 437
Query: 238 QMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQG 297
G+ +P P +F+ +L + I
Sbjct: 438 ------------------------------GKVIPDRSTKPVVFSPTLMLTDEEKARIHA 467
Query: 298 LLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKE-- 355
+ ++ + QEK++++ ++E + E R+ E + +++ E T Q++ K+E
Sbjct: 468 ETALLMEKNK-QEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEME 526
Query: 356 -KKTKRKLQEALEFESKRREQV----EQALKQATTSDSGLRMLKDTG----IPDIEIENN 406
K++++ +E E +KR +++ Q+ + TSD+ + ++D G P+I+ ++
Sbjct: 527 KKESEQAKKEDKETSAKRGKEITGVKRQSKSEHETSDA-KKSVEDRGKRCPTPEIQKKST 585
Query: 407 G-TPHDSAAMQGGN 419
G PH S G+
Sbjct: 586 GDVPHTSVTGDSGS 599
>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
Length = 728
Score = 50.1 bits (118), Expect = 4e-06
Identities = 62/255 (24%), Positives = 111/255 (43%), Gaps = 31/255 (12%)
Query: 179 IANMAAAAQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGS-QTSSHTSSSVSSSPS 237
+A A + SP A S E + P PG+ +T + ++ S
Sbjct: 421 LAPPAQQKVVSSPPCAAAVSRAPEPLATCTQPRKRKLTVDTPGAPETLAPVAAPEEDKDS 480
Query: 238 QMDHHLERMEEVPVQIPIMKSPL------DKIQLTPG-QALPAGFPGPFIFADSLSSVET 290
+ + +E EE + + SP K +PG +ALP+ P AD+ S +E
Sbjct: 481 EAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLGSPGARALPSAVPDAAAPADAPSGLEA 540
Query: 291 LLTNIQGLLKVALDNARIQEK--------QIQQEKKELRLELYREREIRENLERQLAV-- 340
L +++ L+ LD +EK +++QE+K L L +R + + LE
Sbjct: 541 ELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEK-LSAALQAKRSLHQELEFLRVAKK 599
Query: 341 -ELQSRTTMQKRLKKE-----KKTKRKLQEALEFESKRREQVEQALKQATTSDSG----- 389
+L+ T ++ L+KE + ++K++EA E + + ++EQA +QA D G
Sbjct: 600 EKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLKRELEQA-RQARVCDKGCEAGR 658
Query: 390 LRMLKDTGIPDIEIE 404
LR I D++++
Sbjct: 659 LRAKYSAQIEDLQVK 673
Score = 31.6 bits (70), Expect = 1.5
Identities = 14/43 (32%), Positives = 31/43 (72%), Gaps = 1/43 (2%)
Query: 303 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSR 345
+++ +++ + + ++++LR +L RERE RE+LE+ + ELQ +
Sbjct: 667 IEDLQVKLQHAEADREQLRADLLREREAREHLEK-VVKELQEQ 708
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.1 bits (113), Expect = 2e-05
Identities = 31/87 (35%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQ-LAVELQSRTTMQKRLKKEKKTKRKL-QE 364
R +E+++Q+E+ + + EL E E LERQ L E Q Q+RL++E++ +RK +E
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 365 ALEFESKRREQVEQALKQATTSDSGLR 391
E + +RREQ E+ +Q + LR
Sbjct: 314 RREQQEERREQQERREQQEERREQQLR 340
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 5/86 (5%)
Query: 307 RIQEKQIQQEKKELRLELYRERE-----IRENLERQLAVELQSRTTMQKRLKKEKKTKRK 361
R +EK+++QE++E RL+ +E RE RQ ++ + +++RLK+E+ + +
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE 611
Query: 362 LQEALEFESKRREQVEQALKQATTSD 387
+E E KR E E+ +Q S+
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSE 637
Score = 39.7 bits (91), Expect = 0.005
Identities = 24/72 (33%), Positives = 43/72 (59%), Gaps = 5/72 (6%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVE-LQSRTTMQKRLKKEKKTKR----KLQ 363
+E++ QQE++E +L +E + L+RQ E LQ R +++L++E++ +R K +
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
Query: 364 EALEFESKRREQ 375
E E +RREQ
Sbjct: 554 EEKRLEQERREQ 565
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE-A 365
R +E+Q+Q E++E RL R+R+ R E Q A + +SR Q+ ++E++ +R+ +E
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYR--AEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Query: 366 LEFESKRREQVEQ 378
L E RR+Q E+
Sbjct: 1880 LREEHIRRQQKEE 1892
Score = 38.5 bits (88), Expect = 0.012
Identities = 24/84 (28%), Positives = 50/84 (59%), Gaps = 10/84 (11%)
Query: 309 QEKQIQQEKKELRL----ELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE 364
+++++Q+E+++LR EL RER+ E +++L E Q R ++ +++++ +R+ QE
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 365 ALEFESKRREQV------EQALKQ 382
E + +RREQ E+ +Q
Sbjct: 327 RREQQEERREQQLRREQEERREQQ 350
Score = 38.1 bits (87), Expect = 0.016
Identities = 25/74 (33%), Positives = 48/74 (64%), Gaps = 3/74 (4%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+++QQE+++L E RE+ R+ LERQ E + + +++L +E+ KR+ QE LE
Sbjct: 1112 EEEELQQEEEQLLRE-EREKRRRQELERQYREEEEVQQE-EEQLLREEPEKRRRQE-LER 1168
Query: 369 ESKRREQVEQALKQ 382
+ + E+++Q +Q
Sbjct: 1169 QYREEEELQQEEEQ 1182
Score = 37.0 bits (84), Expect = 0.035
Identities = 23/69 (33%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 366
R QE++ +++++E R + R + E E+QL E + R Q R ++E++ +R+ Q
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE-RREQQLRR 366
Query: 367 EFESKRREQ 375
E E +RREQ
Sbjct: 367 EQEEERREQ 375
Score = 37.0 bits (84), Expect = 0.035
Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 5/90 (5%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR----LKKEKKTKRKLQE 364
+E+Q+++E++E R E RE + E+QL E Q R Q R L++E++ +R+ Q
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 365 ALEFESKRREQVEQALKQATTSDSGLRMLK 394
E + RREQ E+ +Q + + LK
Sbjct: 420 RRE-QQLRREQEEERHEQKHEQERREQRLK 448
Score = 37.0 bits (84), Expect = 0.035
Identities = 23/82 (28%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Query: 300 KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTK 359
K AL +E+Q+ QE++E RE+ R+ ERQ E Q + ++ L++E++ +
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 360 RKLQEALEF-ESKRREQVEQAL 380
R+ + ++ + K+ +Q E+ L
Sbjct: 952 RRQERERQYRKDKKLQQKEEQL 973
Score = 36.6 bits (83), Expect = 0.045
Identities = 22/67 (32%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q ++E++E R E RE E E+QL E Q +++L++E++ +R+ Q+
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRRE-QEEERREQQLRREQEEERREQQLRRE 380
Query: 369 ESKRREQ 375
+ RREQ
Sbjct: 381 QQLRREQ 387
Score = 36.6 bits (83), Expect = 0.045
Identities = 26/76 (34%), Positives = 48/76 (63%), Gaps = 7/76 (9%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAV--ELQSRTTMQKRLKKEKKTKRKLQEAL 366
+E+++QQE+++L E RE+ R+ ERQ ELQ +++L +E++ KR+LQE
Sbjct: 992 EEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQE---EEQLLREEREKRRLQER- 1046
Query: 367 EFESKRREQVEQALKQ 382
E + + E+++Q +Q
Sbjct: 1047 ERQYREEEELQQEEEQ 1062
Score = 36.2 bits (82), Expect = 0.059
Identities = 23/84 (27%), Positives = 49/84 (58%), Gaps = 3/84 (3%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
++++ ++ ++ L+LE RE +E E+QL E + R ++RLK++++ +R LQ+ L
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERR--EQRLKRQEEEER-LQQRLRS 534
Query: 369 ESKRREQVEQALKQATTSDSGLRM 392
E + R + E+ +Q + R+
Sbjct: 535 EQQLRREQEERREQLLKREEEKRL 558
Score = 36.2 bits (82), Expect = 0.059
Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+ +E+ E R RER+ RE E Q E R +KR ++E + + + +E ++
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Query: 369 ESKR--REQVEQALKQ 382
E ++ RE+ E+ +Q
Sbjct: 1149 EEEQLLREEPEKRRRQ 1164
Score = 35.8 bits (81), Expect = 0.078
Identities = 22/76 (28%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+ +E++E R RER+ R++ + Q E +KR ++E++ K + +E L+
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 369 ESKR--REQVEQALKQ 382
E ++ RE+ E+ +Q
Sbjct: 999 EEEQLLREEREKRRRQ 1014
Score = 35.4 bits (80), Expect = 0.10
Identities = 24/88 (27%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 309 QEKQIQQEKKELR-LELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRK-LQEAL 366
+E+Q+++E++ R +L RE+++R E + + + ++RLK+E++ +R L+
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 367 EFESKRREQVEQALKQATTSDSGLRMLK 394
E E +E+ +Q LK+ + R LK
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLK 490
Score = 35.0 bits (79), Expect = 0.13
Identities = 23/74 (31%), Positives = 46/74 (62%), Gaps = 3/74 (4%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+++E+ +LR E RE + E+QL E Q R +++L++E++ +R+ +E
Sbjct: 379 REQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRREQEEERHE 435
Query: 369 ESKRREQVEQALKQ 382
+ +E+ EQ LK+
Sbjct: 436 QKHEQERREQRLKR 449
Score = 35.0 bits (79), Expect = 0.13
Identities = 22/77 (28%), Positives = 48/77 (62%), Gaps = 5/77 (6%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSR-TTMQKRLKKEKKTKRKLQEA 365
R +E+Q++++++E + ++ R+ LER+ E Q R T Q++L+++++ ++ L+E
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE- 1752
Query: 366 LEFESKRREQVEQALKQ 382
E R E+ EQ L++
Sbjct: 1753 ---EQLRPEREEQQLRR 1766
Score = 34.7 bits (78), Expect = 0.17
Identities = 21/83 (25%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 304 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAV--------ELQSRTTMQKRLKKE 355
D + +E+Q+ +E++E R RER+ RE E Q E + R ++++ +KE
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 356 KKTKRKLQEALEFESKRREQVEQ 378
++ +++ ++ L E ++R + E+
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQER 1106
Score = 34.3 bits (77), Expect = 0.23
Identities = 20/74 (27%), Positives = 47/74 (63%), Gaps = 3/74 (4%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
++ ++QQE+++L E +R ++E ERQ E + + ++ L +E++T+R+ + LE
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQER-ERQYREEEELQQEEEQLLGEERETRRR--QELER 1078
Query: 369 ESKRREQVEQALKQ 382
+ ++ E+++Q +Q
Sbjct: 1079 QYRKEEELQQEEEQ 1092
Score = 33.9 bits (76), Expect = 0.29
Identities = 22/76 (28%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+ E++E R ER+ R+ E Q E R +KR ++E++ + + +E L+
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 369 ESKR--REQVEQALKQ 382
E ++ RE+ E+ +Q
Sbjct: 1119 EEEQLLREEREKRRRQ 1134
Score = 33.9 bits (76), Expect = 0.29
Identities = 21/70 (30%), Positives = 39/70 (55%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+ +E++E R ER+ RE E Q E R +KR ++E + + + +E L+
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
Query: 369 ESKRREQVEQ 378
E ++ + EQ
Sbjct: 1179 EEEQLLREEQ 1188
Score = 33.5 bits (75), Expect = 0.38
Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 12/86 (13%)
Query: 309 QEKQIQQEKKELRLELYREREIREN------------LERQLAVELQSRTTMQKRLKKEK 356
+E+Q+++E++E R E E+E RE L+R+ E + +++LK+++
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 357 KTKRKLQEALEFESKRREQVEQALKQ 382
+ +R+ + E +RREQ E+ +Q
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQ 506
Score = 33.5 bits (75), Expect = 0.38
Identities = 24/78 (30%), Positives = 43/78 (55%), Gaps = 4/78 (5%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLER---QLAVELQSRTTMQ-KRLKKEKKTKRKLQE 364
Q K+ Q+E++ R E E RE ER QL E + R + KR ++E++ +++L+
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Query: 365 ALEFESKRREQVEQALKQ 382
+ ++ E+ EQ LK+
Sbjct: 535 EQQLRREQEERREQLLKR 552
Score = 33.5 bits (75), Expect = 0.38
Identities = 20/76 (26%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+QQE+++L E RE+ R+ ERQ + + + ++ L +E + +R+ + ++
Sbjct: 932 EEEQLQQEEEQLLRE-EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 369 --ESKRREQVEQALKQ 382
E + +++ EQ L++
Sbjct: 991 REEEELQQEEEQLLRE 1006
Score = 33.5 bits (75), Expect = 0.38
Identities = 24/75 (32%), Positives = 45/75 (60%), Gaps = 5/75 (6%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAV-ELQSRTTMQKRLKKEKKTKRKLQEALE 367
+E+++QQE+++L L E E R ER+ E + +++L +E++ KR+ QE LE
Sbjct: 1082 KEEELQQEEEQL---LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE-LE 1137
Query: 368 FESKRREQVEQALKQ 382
+ + E+V+Q +Q
Sbjct: 1138 RQYREEEEVQQEEEQ 1152
Score = 33.1 bits (74), Expect = 0.50
Identities = 24/74 (32%), Positives = 43/74 (58%), Gaps = 4/74 (5%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q Q+ ++E +L +E E RE E + E Q R Q+ ++E++ +R+ +E E
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERR--EQQERREQQEE-RREQQLRREQEERRE- 348
Query: 369 ESKRREQVEQALKQ 382
+ RREQ E+ +Q
Sbjct: 349 QQLRREQEEERREQ 362
Score = 33.1 bits (74), Expect = 0.50
Identities = 27/85 (31%), Positives = 50/85 (58%), Gaps = 15/85 (17%)
Query: 309 QEKQIQQEKKELRLELYREREIR-----ENLERQLAVELQSRTTMQKR----LKKEKKTK 359
+E+Q+++E++E R RE+++R E E+QL E Q R Q R L++E++ +
Sbjct: 347 REQQLRREQEEER----REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 360 RKLQEALEFESKRREQV--EQALKQ 382
R+ Q E + +R +Q+ EQ L++
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRR 427
Score = 32.7 bits (73), Expect = 0.66
Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 10/84 (11%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL-- 366
+E+Q+ +E++E R ER+ R+ E Q E R +KR +E++ + + +E L
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058
Query: 367 --------EFESKRREQVEQALKQ 382
E E++RR+++E+ ++
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRK 1082
Score = 32.3 bits (72), Expect = 0.86
Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 15/85 (17%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRL---------------K 353
+E+Q+++E++E R + + +E E L+++L E Q R ++R +
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 354 KEKKTKRKLQEALEFESKRREQVEQ 378
+E++ KR+ +E + KR E+ Q
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQ 587
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/84 (29%), Positives = 46/84 (54%), Gaps = 11/84 (13%)
Query: 309 QEKQIQQEKK---ELRLELYREREIREN-------LERQLAVELQSRTTMQKRLKKEKKT 358
QE++ QE++ + R +L ER+ R + L+ QL E Q ++ L++E++
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 359 KRKLQEALEFESKRREQVEQALKQ 382
KR+ QE E + + EQ++Q +Q
Sbjct: 920 KRRRQEQ-ERQYREEEQLQQEEEQ 942
Score = 31.6 bits (70), Expect = 1.5
Identities = 21/76 (27%), Positives = 44/76 (57%), Gaps = 9/76 (11%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+++E++E R + R + E E+QL E Q+ ++E++ +R+ Q E
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRRE-------QEEERREQQLRREQQLRREQ 387
Query: 369 ESKRREQV--EQALKQ 382
+ +R +Q+ EQ L++
Sbjct: 388 QLRREQQLRREQQLRR 403
Score = 31.6 bits (70), Expect = 1.5
Identities = 20/69 (28%), Positives = 36/69 (52%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+ +E+ E R ER+ RE E Q E R +KR ++ ++ R+ +E
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 369 ESKRREQVE 377
+ K+R + E
Sbjct: 1209 KRKQRYRDE 1217
Score = 31.2 bits (69), Expect = 1.9
Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQ-KRLKKEKKTKRKLQEALE 367
+E+Q+++E+ +LR E RE + E+QL E Q R Q +R ++E++ ++K ++
Sbjct: 385 REQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 368 FESKRREQVEQ 378
+ +REQ E+
Sbjct: 444 EQRLKREQEER 454
Score = 31.2 bits (69), Expect = 1.9
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 14/97 (14%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR---LKKEKKTKRKLQEA 365
+E+++++E++E R L RE E + + + +L+ ++R LK E++ +R+ QE
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 366 LEFE-----SKRREQ------VEQALKQATTSDSGLR 391
E + +RREQ E+ L+Q S+ LR
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Score = 31.2 bits (69), Expect = 1.9
Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 7/73 (9%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQ------LAVELQSRTTMQKRLKKEKKTKRKL 362
+++++++E++E RLE +RE E LE++ L E Q+ LK E++ +R+
Sbjct: 586 RQQRLKREQEE-RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Query: 363 QEALEFESKRREQ 375
Q+ + +RREQ
Sbjct: 645 QQLRREQQERREQ 657
Score = 31.2 bits (69), Expect = 1.9
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 9/83 (10%)
Query: 304 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEK------- 356
+ R Q + ++ ++E R +L + E E ++QL E Q R ++RLK+E+
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR--EQRLKREEEEERLEQ 670
Query: 357 KTKRKLQEALEFESKRREQVEQA 379
+ KR+ +E + E+ EQA
Sbjct: 671 RLKREHEEERREQELAEEEQEQA 693
Score = 31.2 bits (69), Expect = 1.9
Identities = 22/87 (25%), Positives = 47/87 (54%), Gaps = 10/87 (11%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+E+Q+ E+ E R RE++ RE E Q +++L +E++ KR+ QE E
Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQ---------QEEEQLLREEREKRRRQE-WER 1018
Query: 369 ESKRREQVEQALKQATTSDSGLRMLKD 395
+ +++++++Q +Q + R L++
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQE 1045
Score = 30.8 bits (68), Expect = 2.5
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 7/82 (8%)
Query: 308 IQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKR----LKKEKKTK---R 360
+QE++ Q +++ R +RE E+R + + +E + R Q+R LK+E++ + R
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 361 KLQEALEFESKRREQVEQALKQ 382
+ Q + + K RE+ +Q +Q
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQ 1426
Score = 30.8 bits (68), Expect = 2.5
Identities = 21/79 (26%), Positives = 46/79 (58%), Gaps = 6/79 (7%)
Query: 309 QEKQIQQEKKELRLELY-REREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALE 367
+E+Q+ QE++E +L R+R+ E E+QL + + R ++ L+ ++ ++ L+E +
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEE-EQQLRRQERDRKFREQELRSQEPERKFLEEEQQ 1523
Query: 368 FESKRRE----QVEQALKQ 382
++R+ Q EQ L++
Sbjct: 1524 LHRQQRQRKFLQEEQQLRR 1542
Score = 30.0 bits (66), Expect = 4.3
Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQL--AVELQSRTTMQKRLKKEKKTKRKLQE 364
R +E+ Q+E++ L E RE R+ LERQ ELQ R + EK+ +++ +
Sbjct: 1051 REEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 365 ALEFESKRREQVEQALKQ 382
E + +++ EQ L++
Sbjct: 1109 QCREEEELQQEEEQLLRE 1126
Score = 29.6 bits (65), Expect = 5.6
Identities = 16/69 (23%), Positives = 37/69 (53%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 366
R+ +++ ++E ++ L +E E + E Q ELQ ++L++++ + + +E
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Query: 367 EFESKRREQ 375
+ + RREQ
Sbjct: 296 QQQRLRREQ 304
Score = 29.6 bits (65), Expect = 5.6
Identities = 24/95 (25%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Query: 289 ETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTM 348
E L + LL+ + R QE + +Q ++E ++ E+ +RE E++ EL+ +
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELE-RQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 349 QKRL-KKEKKTKRKLQEALEFESKRREQVEQALKQ 382
++ L ++E++ R+ QE E +R+ + E+ L++
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207
Score = 29.6 bits (65), Expect = 5.6
Identities = 15/72 (20%), Positives = 45/72 (62%), Gaps = 3/72 (4%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSR--TTMQKRLKKEKKTKRKLQEAL 366
+E+Q++ +++E +L R+R+ RE E+QL+ + + R +++++++++ ++ L+E
Sbjct: 1395 EEQQLRCQEREQQLRQDRDRKFREE-EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 367 EFESKRREQVEQ 378
+ +R + +
Sbjct: 1454 QLRQERHRKFRE 1465
Score = 29.6 bits (65), Expect = 5.6
Identities = 24/82 (29%), Positives = 48/82 (58%), Gaps = 10/82 (12%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRT-TMQKRLKK----EKKTKRKLQ 363
+E+Q++++++ + R+R+ RE E QL E + + + Q+R +K E+K +R+ Q
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFRE--EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 364 EALEFESK---RREQVEQALKQ 382
E E + RR++ +Q L+Q
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQ 1615
Score = 29.3 bits (64), Expect = 7.3
Identities = 20/77 (25%), Positives = 43/77 (55%), Gaps = 7/77 (9%)
Query: 299 LKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKT 358
LK + R+Q++ +++ E RE+ ++ E++L E + ++RLK+E++
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR-----EQRLKREQEE 573
Query: 359 KRKLQEALEFESKRREQ 375
+R + L+ E +RR+Q
Sbjct: 574 RR--DQLLKREEERRQQ 588
Score = 29.3 bits (64), Expect = 7.3
Identities = 21/74 (28%), Positives = 43/74 (58%), Gaps = 7/74 (9%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTK-----RK 361
R +E+ Q+E++ LR E E+ R+ LERQ E + + ++ L++E++ + R+
Sbjct: 1141 REEEEVQQEEEQLLREE--PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
Query: 362 LQEALEFESKRREQ 375
+E E + ++R+Q
Sbjct: 1199 YREEEELQRQKRKQ 1212
Score = 29.3 bits (64), Expect = 7.3
Identities = 23/80 (28%), Positives = 44/80 (55%), Gaps = 13/80 (16%)
Query: 309 QEKQIQQEKKELRLELY-REREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALE 367
+E+Q+ QE +E +L R+R+ RE E+QL +R ++E+K ++ Q+
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREE-EQQL-----------RRQERERKFLQEEQQLRR 1718
Query: 368 FESKRREQVEQALKQATTSD 387
E +R+ + E+ L+Q T +
Sbjct: 1719 QELERKFREEEQLRQETEQE 1738
Score = 28.9 bits (63), Expect = 9.5
Identities = 18/76 (23%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 366
R +E+Q+ +++++ + ++ R+ ER+ E Q Q+R +K ++ ++ LQE
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ--LRQERHRKFREEEQLLQERE 1474
Query: 367 EFESKRREQVEQALKQ 382
E + R+E+ + L++
Sbjct: 1475 EQQLHRQERDRKFLEE 1490
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 47.0 bits (110), Expect = 3e-05
Identities = 27/70 (38%), Positives = 43/70 (61%), Gaps = 2/70 (2%)
Query: 304 DNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ 363
+ AR+Q +++Q E + RLE RER RE LER+ + R Q+R+ +E++ R+ Q
Sbjct: 659 EKARLQRERLQLECQRQRLE--RERMERERLERERMRVERERRKEQERIHREREELRRQQ 716
Query: 364 EALEFESKRR 373
E L +E +RR
Sbjct: 717 EQLRYEQERR 726
Score = 36.2 bits (82), Expect = 0.059
Identities = 21/72 (29%), Positives = 46/72 (63%), Gaps = 7/72 (9%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQ-LAVELQSRTTMQKRLKKEKKTKRKLQ-EAL 366
+ ++ +Q ++E RLE + ER+ + L+R+ L +E Q ++RL++E+ + +L+ E +
Sbjct: 638 RRREREQREREQRLEAFHERKEKARLQRERLQLECQ-----RQRLERERMERERLERERM 692
Query: 367 EFESKRREQVEQ 378
E +RR++ E+
Sbjct: 693 RVERERRKEQER 704
Score = 32.7 bits (73), Expect = 0.66
Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEAL 366
R +E+Q Q+E++ E RERE RE R+ +E + RL++E+ ++ L
Sbjct: 621 RERERQRQREREIRETERRREREQRE---REQRLEAFHERKEKARLQRERLQLECQRQRL 677
Query: 367 EFESKRREQVEQ 378
E E RE++E+
Sbjct: 678 ERERMERERLER 689
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 16/130 (12%)
Query: 286 SSVETLLTNIQGLL------KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLA 339
S++E+ L + Q LL K++L + KQ++ EK R +L E E + NLE+Q+A
Sbjct: 1304 SALESQLQDTQELLQEENRQKLSLST---KLKQVEDEKNSFREQLEEEEEAKHNLEKQIA 1360
Query: 340 VELQSRTTMQKR-------LKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRM 392
M+K+ L+ ++ KRKLQ+ LE S+R E+ A + + + L+
Sbjct: 1361 TLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQ 1420
Query: 393 LKDTGIPDIE 402
D + D++
Sbjct: 1421 ELDDLLVDLD 1430
Score = 35.0 bits (79), Expect = 0.13
Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 8/118 (6%)
Query: 285 LSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYRER----EIRENLERQLAV 340
L+ +ETL + + K+ L E ++ E +ELR L ++ EI +LE ++
Sbjct: 868 LTEMETLQSQLMAE-KLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 341 ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGI 398
E + +Q KK ++ ++L+E LE E R++++ + T+++ L+ L++ I
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ---LEKVTTEAKLKKLEEEQI 981
Score = 30.4 bits (67), Expect = 3.3
Identities = 24/113 (21%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Query: 284 SLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQ 343
S++++E + ++ L + KQ+++ +K+L+ L + + R N E Q +
Sbjct: 1808 SITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAE-QYKDQAD 1866
Query: 344 SRTTMQKRLKKE-KKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKD 395
+T K+LK++ ++ + + Q A K + ++E A + A + + LK+
Sbjct: 1867 KASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKN 1919
Score = 30.0 bits (66), Expect = 4.3
Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 27/140 (19%)
Query: 283 DSLSSVET-------LLTNIQGLLK------VALDNARIQEKQIQQEKKELRLELYRERE 329
DS+ +ET L +++GL + A D + ++QQE +L ++L +R+
Sbjct: 1375 DSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQ 1434
Query: 330 IRENLERQ-------------LAVELQSRTTMQKRLKKEKKTKR-KLQEALEFESKRREQ 375
NLE++ ++ + + +EK+TK L ALE +++ +
Sbjct: 1435 SACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE 1494
Query: 376 VEQALKQATTSDSGLRMLKD 395
+E+ KQ T L KD
Sbjct: 1495 LERLNKQFRTEMEDLMSSKD 1514
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 46.6 bits (109), Expect = 4e-05
Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)
Query: 292 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 349
+ N+ G + D R+Q++ ++ + R +L +E+++RE E RQL E Q R Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 350 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 378
K RL+++++ +R+ + E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
Query: 291 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 350
LL Q ++ + R E+Q Q+ ++E R + RE+ RE E++ EL+ R ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449
Query: 351 RLKKEKKTKRKLQEALEFESKRREQVEQALK 381
++ ++ KR+++ E+ ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 46.6 bits (109), Expect = 4e-05
Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)
Query: 292 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 349
+ N+ G + D R+Q++ ++ + R +L +E+++RE E RQL E Q R Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 350 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 378
K RL+++++ +R+ + E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
Query: 291 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 350
LL Q ++ + R E+Q Q+ ++E R + RE+ RE E++ EL+ R ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449
Query: 351 RLKKEKKTKRKLQEALEFESKRREQVEQALK 381
++ ++ KR+++ E+ ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 46.6 bits (109), Expect = 4e-05
Identities = 29/93 (31%), Positives = 53/93 (56%), Gaps = 6/93 (6%)
Query: 292 LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLE--RQLAVELQSRTTMQ 349
+ N+ G + D R+Q++ ++ + R +L +E+++RE E RQL E Q R Q
Sbjct: 343 IVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQ 402
Query: 350 K----RLKKEKKTKRKLQEALEFESKRREQVEQ 378
K RL+++++ +R+ + E E +RREQ E+
Sbjct: 403 KEQRRRLEEQQRREREARRQQEREQRRREQEEK 435
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 1/91 (1%)
Query: 291 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 350
LL Q ++ + R E+Q Q+ ++E R + RE+ RE E++ EL+ R ++
Sbjct: 391 LLAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEEKRRLEELERRRKEEE 449
Query: 351 RLKKEKKTKRKLQEALEFESKRREQVEQALK 381
++ ++ KR+++ E+ ++ E+ ++ L+
Sbjct: 450 ERRRAEEEKRRVEREQEYIRRQLEEEQRHLE 480
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 46.6 bits (109), Expect = 4e-05
Identities = 62/269 (23%), Positives = 111/269 (41%), Gaps = 41/269 (15%)
Query: 143 NRLDLPFMMMPH----PLLPVSLPPASVAMAMNQMNHLNTIANMAAAAQIHSPLSRAGTS 198
+RL LP +PH P SLPP SV AA AQ+ P S
Sbjct: 327 SRLWLPSKSLPHLPGTPRPTSSLPPGSVK---------------AAPAQVRPP-SPGNIR 370
Query: 199 VIKERIPESPSPAPSLEENHRPGSQTS-SHTSSSVSSSPSQMDHHLERMEEVPVQIPIMK 257
+K + P +E + ++ S + V + ++ EV P M
Sbjct: 371 PVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEEATVEERTPAEPEVGPAAPAM- 429
Query: 258 SPLDKIQLTPGQA-LPAGFPGPFIFADSLSSVETLL--------TNIQGLLKVALDNARI 308
+P P A PA P P + + S+V T+ + ++ + R+
Sbjct: 430 APAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRL 489
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR-KLQEALE 367
+Q ++E+ RER +E LERQ EL R ++ ++E++++R + ++A E
Sbjct: 490 AREQREKEE--------RERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQARE 541
Query: 368 FESK-RREQVEQALKQATTSDSGLRMLKD 395
E + +R+ E+AL++ ++ R ++
Sbjct: 542 KEEQLQRQAEERALREREEAERAQRQKEE 570
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/103 (29%), Positives = 58/103 (56%), Gaps = 8/103 (7%)
Query: 300 KVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK-RLKKEKKT 358
++ + AR +E+Q+Q++ +E L RERE E +RQ E + R ++ R ++EK
Sbjct: 533 RLEAEQAREKEEQLQRQAEERAL---REREEAERAQRQKEEEARVREEAERVRQEREKHF 589
Query: 359 KRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDI 401
+R+ QE LE R++++E+ +K+ +++ + D DI
Sbjct: 590 QREEQERLE----RKKRLEEIMKRTRRTEATDKKTSDQRNGDI 628
Score = 32.3 bits (72), Expect = 0.86
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 11/68 (16%)
Query: 328 REIRENLERQLAV--------ELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQA 379
RE RE E+QLA E ++R +K L++ KK +L+E + E +RR VE+
Sbjct: 71 RERREEREKQLAAREIVWLEREERARQHYEKHLEERKK---RLEEQRQKEERRRAAVEEK 127
Query: 380 LKQATTSD 387
+Q D
Sbjct: 128 RRQRLEED 135
Score = 29.3 bits (64), Expect = 7.3
Identities = 16/54 (29%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKR 360
R++E++ ++E++ +E R + + E+ ER AV R TM++ K ++K R
Sbjct: 109 RLEEQRQKEERRRAAVEEKRRQRLEEDKERHEAVV---RRTMERSQKPKQKHNR 159
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 45.4 bits (106), Expect = 1e-04
Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Query: 308 IQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALE 367
+ +Q +E+KE RLE + +E LE++ A + R ++RL++E K + K + E
Sbjct: 569 LARRQTIEERKE-RLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQE 627
Query: 368 FESKRREQVEQALKQATTSDSGLRMLKDTGIPDIE 402
E +++ V + L+Q ++ G + KD I D+E
Sbjct: 628 HEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662
Score = 35.8 bits (81), Expect = 0.078
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 16/87 (18%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRE--NLERQLAVELQSR------------TTMQKRL 352
R++E++ +Q K+E R+ YRE+E E E Q+ E + R Q+R+
Sbjct: 790 RLEERK-RQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERV 848
Query: 353 KK-EKKTKRKLQEALEFESKRREQVEQ 378
KK E+ ++K Q LE E + R + E+
Sbjct: 849 KKLEEVERKKRQRELEIEERERRREEE 875
Score = 31.2 bits (69), Expect = 1.9
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 6/98 (6%)
Query: 289 ETLLTNIQGLLKVALDNARIQEKQIQ-QEKKELRLELYREREIRENL---ERQLAVELQS 344
E +T +Q + AL++ + ++ ++ +RL+ R+ E L E +LA E +
Sbjct: 730 EERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHN 789
Query: 345 RTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQ 382
R +KR +KE++ +E E E +R E EQ LK+
Sbjct: 790 RLEERKRQRKEERRITYYREKEEEEQRRAE--EQMLKE 825
>gi|67763814 death-inducing-protein [Homo sapiens]
Length = 578
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 17/127 (13%)
Query: 232 VSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETL 291
++ SP+ D E +E+P+++P SP D +L PAG PG I A +
Sbjct: 21 LAESPNASD--TECSDEIPLKVP-RTSPRDSEELRD----PAG-PGTLIMATGVQDFNRT 72
Query: 292 ----LTNIQGLLKVALDNARIQEKQIQQEKKE-----LRLELYREREIRENLERQLAVEL 342
L I+G L++AL ++++++ ++E LR EL RER+ R LE+++ L
Sbjct: 73 EFDRLNEIKGHLEIALLEKHFLQEELRKLREETNAEMLRQELDRERQRRMELEQKVQEVL 132
Query: 343 QSRTTMQ 349
++RT Q
Sbjct: 133 KARTEEQ 139
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 43.1 bits (100), Expect = 5e-04
Identities = 23/82 (28%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Query: 300 KVALDNARIQEKQIQQEKKELRLE---LYREREIRENLERQLAVELQSRTTMQKRLKKEK 356
++ + R + +++Q+E++ L +E L RER RE LER+ Q R +R+ +E+
Sbjct: 629 RIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARER 688
Query: 357 KTKRKLQEALEFESKRREQVEQ 378
+ R+ Q+ L +E ++R +++
Sbjct: 689 EELRRQQQQLRYEQEKRNSLKR 710
Score = 38.1 bits (87), Expect = 0.016
Identities = 22/85 (25%), Positives = 50/85 (58%), Gaps = 5/85 (5%)
Query: 299 LKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKT 358
L+ A++ R +E ++ ++ R+ + RERE RE L+R E + +++L++E+
Sbjct: 607 LRRAMELRRRREIAERERRERERIRIIREREERERLQR----ERERLEIERQKLERERME 662
Query: 359 KRKLQ-EALEFESKRREQVEQALKQ 382
+ +L+ E + E +RR++ E+ ++
Sbjct: 663 RERLERERIRIEQERRKEAERIARE 687
Score = 33.5 bits (75), Expect = 0.38
Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 3/74 (4%)
Query: 307 RIQEKQIQQEKKELRLELYREREI--RENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE 364
R++E ++ E+ +EL R REI RE ER+ ++ R ++RL++E++ ++
Sbjct: 596 RLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREE-RERLQRERERLEIERQ 654
Query: 365 ALEFESKRREQVEQ 378
LE E RE++E+
Sbjct: 655 KLERERMERERLER 668
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 43.1 bits (100), Expect = 5e-04
Identities = 23/82 (28%), Positives = 48/82 (58%), Gaps = 3/82 (3%)
Query: 300 KVALDNARIQEKQIQQEKKELRLE---LYREREIRENLERQLAVELQSRTTMQKRLKKEK 356
++ + R + +++Q+E++ L +E L RER RE LER+ Q R +R+ +E+
Sbjct: 647 RIRIIREREERERLQRERERLEIERQKLERERMERERLERERIRIEQERRKEAERIARER 706
Query: 357 KTKRKLQEALEFESKRREQVEQ 378
+ R+ Q+ L +E ++R +++
Sbjct: 707 EELRRQQQQLRYEQEKRNSLKR 728
Score = 38.1 bits (87), Expect = 0.016
Identities = 22/85 (25%), Positives = 50/85 (58%), Gaps = 5/85 (5%)
Query: 299 LKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKT 358
L+ A++ R +E ++ ++ R+ + RERE RE L+R E + +++L++E+
Sbjct: 625 LRRAMELRRRREIAERERRERERIRIIREREERERLQR----ERERLEIERQKLERERME 680
Query: 359 KRKLQ-EALEFESKRREQVEQALKQ 382
+ +L+ E + E +RR++ E+ ++
Sbjct: 681 RERLERERIRIEQERRKEAERIARE 705
Score = 33.5 bits (75), Expect = 0.38
Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 3/74 (4%)
Query: 307 RIQEKQIQQEKKELRLELYREREI--RENLERQLAVELQSRTTMQKRLKKEKKTKRKLQE 364
R++E ++ E+ +EL R REI RE ER+ ++ R ++RL++E++ ++
Sbjct: 614 RLREHLVRFERLRRAMELRRRREIAERERRERERIRIIREREE-RERLQRERERLEIERQ 672
Query: 365 ALEFESKRREQVEQ 378
LE E RE++E+
Sbjct: 673 KLERERMERERLER 686
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 43.1 bits (100), Expect = 5e-04
Identities = 59/285 (20%), Positives = 114/285 (40%), Gaps = 45/285 (15%)
Query: 127 GGAPTLNPLQQNHLLTNRLDLPFM--MMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAA 184
GG P + P Q L LP M P P + P++ M ++ ++ + ++ A
Sbjct: 399 GGQPVVTPSVQPSLHPAHPALPQMTSQAPQPSVTGLQAPSAALMQVSSLDSHSAVSGNAQ 458
Query: 185 AAQIHSPLSR----AGTSVIKERIPESPS-PAPSLEENHRPGS------------QTSSH 227
+ Q ++ + ++V + P P PAP + H GS Q ++
Sbjct: 459 SFQPYAGMQAYAYPQASAVTSQLQPVRPLYPAPLSQPPHFQGSGDMASFLMTEARQHNTE 518
Query: 228 TSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSS 287
+VS +MDH + ++EE + K L P ++
Sbjct: 519 IRMAVSKVADKMDHLMTKVEE------LQKHSAGNSMLIPSMSVTM-------------E 559
Query: 288 VETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTT 347
+++NIQ +++ +N R++++ ++ K R+E ++ I E +ER QS
Sbjct: 560 TSMIMSNIQRIIQ---ENERLKQEILE---KSNRIEEQNDK-ISELIERNQRYVEQSNLM 612
Query: 348 MQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRM 392
M+KR + Q + + + +V + L AT S L++
Sbjct: 613 MEKRNNSLQTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQL 657
>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
1 [Homo sapiens]
Length = 862
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/113 (25%), Positives = 61/113 (53%), Gaps = 10/113 (8%)
Query: 299 LKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKT 358
LK L+ ++++ Q++ +E +L +EI+ +LE QL E ++ T+++ + +EK
Sbjct: 744 LKAELERIKVEKGQLESTLREKSQQLESLQEIKISLEEQLKKETAAKATVEQLMFEEKNK 803
Query: 359 KRKLQEALEF-ESKRREQVE---------QALKQATTSDSGLRMLKDTGIPDI 401
++LQ L+ E +R+ V+ + ++QA + + +L DT + DI
Sbjct: 804 AQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQADSLERIRAILNDTKLTDI 856
Score = 29.6 bits (65), Expect = 5.6
Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 313 IQQEKKELRLELYREREIRENLERQL-AVELQSRTTMQKRLKKEKKTKRKLQEALEFESK 371
+Q+E +L R ++ N E+QL +++Q T + ++KK + R+ + LE K
Sbjct: 518 LQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAET-RDQVKKLQLMLRQANDQLEKTMK 576
Query: 372 RREQVEQALKQATTSDS 388
++++E +KQ++ S
Sbjct: 577 DKQELEDFIKQSSEDSS 593
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 43.1 bits (100), Expect = 5e-04
Identities = 44/181 (24%), Positives = 83/181 (45%), Gaps = 14/181 (7%)
Query: 201 KERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPL 260
KE ESPS A E+ + + S+ S+ +SP+ + P ++P
Sbjct: 511 KEEAKESPSAAGP-EDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPT 569
Query: 261 DKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKEL 320
D LT A P P + + S T+ + ++ + R +Q ++E++E
Sbjct: 570 DAAVLTSPPA-----PAPPV---TPSKPMAGTTDREEATRLLAEKRRQAREQREREEQER 621
Query: 321 RLELYREREIRENLERQLAVELQSRT--TMQKRLKKEKKTKRKLQEALEFESKRREQVEQ 378
RL+ R++ +R E QLA E ++R + R ++E++ + K Q E + + ++Q E+
Sbjct: 622 RLQAERDKRMR---EEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEE 678
Query: 379 A 379
A
Sbjct: 679 A 679
Score = 30.0 bits (66), Expect = 4.3
Identities = 17/71 (23%), Positives = 41/71 (57%), Gaps = 2/71 (2%)
Query: 309 QEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEF 368
+++++Q++K+E E E R+ LER+ + Q + ++R + E+ KR + +
Sbjct: 668 EQERLQKQKEEAEARSREEAE-RQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVS- 725
Query: 369 ESKRREQVEQA 379
E+K+++ ++A
Sbjct: 726 ETKQKQDSKEA 736
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 42.0 bits (97), Expect = 0.001
Identities = 56/249 (22%), Positives = 101/249 (40%), Gaps = 23/249 (9%)
Query: 151 MMPHPLLPVSLPPASVAMAMNQMNHLNTIAN-MAAAAQIHSPLSRAGTSVIKERIPESPS 209
M P P LP P + + ++ N L + Q SP AG K++ SP
Sbjct: 1 MWPQPYLP----PHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPE 56
Query: 210 PAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQ 269
S H PG + ++ SS ++ E +E + Q ++ L++ + T +
Sbjct: 57 TTTS-GGGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNE 115
Query: 270 ALPAGFPGPFIFADSLSSVETL--LTNIQGLLKVALDNARIQEKQIQQEKKELRLELYRE 327
I + +ET+ LT + LK L + + + ++E K+L L
Sbjct: 116 ----------IHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYS 165
Query: 328 REIRENLERQL-AVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTS 386
+ + LER L AV Q + + +E +R+LQ+ + K R + + Q T S
Sbjct: 166 LQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRLQQTI----KERALLNAHVTQVTES 221
Query: 387 DSGLRMLKD 395
+++ +D
Sbjct: 222 LKQVQLERD 230
Score = 35.0 bits (79), Expect = 0.13
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 13/148 (8%)
Query: 243 LERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKVA 302
+ R++E+ + +K+ + + P A PA D + + ++G L+
Sbjct: 265 IHRIQELERSLSELKNQMAE---PPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQ 321
Query: 303 LDN-------ARIQEKQIQQEKKELR-LELYREREIRENLERQLAVELQSRTTMQK--RL 352
++N ++ Q++++Q++++ LR E R RE E+ + Q +T ++ RL
Sbjct: 322 VENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERL 381
Query: 353 KKEKKTKRKLQEALEFESKRREQVEQAL 380
+K+++ RK +E L E +R ++ E+ L
Sbjct: 382 RKQEQRLRKQEERLRKEEERLQKQEKRL 409
Score = 28.9 bits (63), Expect = 9.5
Identities = 22/79 (27%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Query: 307 RIQEKQIQQEKKELRLELYREREIRENLERQ---LAVELQSRTTMQKRLKKEKKTKRKLQ 363
R QE Q +E++ L + R RE ++ L+ Q L + Q ++RL+KE++ +K +
Sbjct: 347 REQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQE 406
Query: 364 EALEFESKRREQVEQALKQ 382
+ L + +R + E+ L++
Sbjct: 407 KRLWDQEERLWKKEERLQK 425
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 42.0 bits (97), Expect = 0.001
Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 3/118 (2%)
Query: 281 FADSLSSVETLLTNIQGLLKVALD---NARIQEKQIQQEKKELRLELYREREIRENLERQ 337
FA +S+E+ L + Q LL+ N + +Q+++EK L+ + E E R+NLE+Q
Sbjct: 1306 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365
Query: 338 LAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQATTSDSGLRMLKD 395
+ +K++ + T L+EA + K E + Q L++ + L K+
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN 1423
Score = 35.4 bits (80), Expect = 0.10
Identities = 37/140 (26%), Positives = 61/140 (43%), Gaps = 27/140 (19%)
Query: 283 DSLSSVETLLTNIQGLLK-------------VALDNARIQEKQIQQEKKELRLELYRERE 329
D L ++E+L + LLK +A D + ++QQE +L ++L +R+
Sbjct: 1382 DDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQ 1441
Query: 330 IRENLER------QLAVELQSRTTMQKRLK-------KEKKTKR-KLQEALEFESKRREQ 375
+ NLE+ QL E +S + + +EK+TK L ALE + +E+
Sbjct: 1442 VASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEE 1501
Query: 376 VEQALKQATTSDSGLRMLKD 395
E+ KQ L KD
Sbjct: 1502 FERQNKQLRADMEDLMSSKD 1521
Score = 33.1 bits (74), Expect = 0.50
Identities = 37/169 (21%), Positives = 71/169 (42%), Gaps = 8/169 (4%)
Query: 214 LEENHRPGSQTSSHTSSSVSSSPSQMDHHLERMEEVPVQIPIMKSPLDKIQLTPGQALPA 273
LEE + +T + + +++ E+ QI +K L K + AL
Sbjct: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
Query: 274 GFPGPFIFADSLSSVETLLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIREN 333
G ++L V L I L + ++ + + +++K++L EL E
Sbjct: 1099 GDDETLHKNNALKVVRELQAQIAELQE-DFESEKASRNKAEKQKRDLSEEL-------EA 1150
Query: 334 LERQLAVELQSRTTMQKRLKKEKKTKRKLQEALEFESKRREQVEQALKQ 382
L+ +L L + Q+ K ++ +L++ALE E+K E Q ++Q
Sbjct: 1151 LKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQ 1199
Score = 32.7 bits (73), Expect = 0.66
Identities = 26/91 (28%), Positives = 50/91 (54%), Gaps = 10/91 (10%)
Query: 310 EKQIQQEKKEL----RLELYREREIRE---NLERQLAVELQSRTTMQKRLKKEKKTKRKL 362
E+Q++QE KE +L E++++E +E + Q + M+K + K+ KR+L
Sbjct: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886
Query: 363 QEALEFESK---RREQVEQALKQATTSDSGL 390
+EA E ++ R ++++ L AT ++ GL
Sbjct: 1887 EEAEEEATRANASRRKLQRELDDATEANEGL 1917
Score = 29.3 bits (64), Expect = 7.3
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 9/92 (9%)
Query: 300 KVALDNARIQEKQIQQEKKELRLELYREREIREN---------LERQLAVELQSRTTMQK 350
K+ L+ + K + E++ L LE + I+E QLA E + + K
Sbjct: 968 KLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAK 1027
Query: 351 RLKKEKKTKRKLQEALEFESKRREQVEQALKQ 382
K++ L+E L+ E K R+++E+A ++
Sbjct: 1028 IRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
Length = 1012
Score = 42.0 bits (97), Expect = 0.001
Identities = 49/220 (22%), Positives = 94/220 (42%), Gaps = 39/220 (17%)
Query: 190 SPLSRAGTSVIKERIPE--------SPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDH 241
+PL +A S+ E E SPSP P P S + VSS P Q
Sbjct: 737 TPLPKAKRSLESEMYLEGLGRSHIASPSPCPDRMPLPSPTESRHSLSIPPVSSPPEQKVG 796
Query: 242 HLERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFP-----------GPFIFADSLSSVET 290
R E+ + S +DK+ + + F G A +S V+
Sbjct: 797 LYRRQTELQDKSEF--SDVDKLAFKDNEEFESSFESAGNMPRQLEMGGLSPAGDMSHVDA 854
Query: 291 LLTNIQGLLKVALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQK 350
+ ++ + + +KQI+++K+E E RE++++E +R E + ++ +Q+
Sbjct: 855 AAAAVP----LSYQHPSVDQKQIEEQKEE---EKIREQQVKERRQR----EERRQSNLQE 903
Query: 351 RLKKEKKTKRKL-------QEALEFESKRREQVEQALKQA 383
L++E++ KL +E+L+ + K+ ++E L+ +
Sbjct: 904 VLERERRELEKLYQERKMIEESLKIKIKKELEMENELEMS 943
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 8/88 (9%)
Query: 303 LDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVE--------LQSRTTMQKRLKK 354
L R QE++ Q+ +++ R E R + R ERQLA + LQ+ +Q+R K
Sbjct: 684 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 743
Query: 355 EKKTKRKLQEALEFESKRREQVEQALKQ 382
+ K +LQ LE + K+ EQ A +Q
Sbjct: 744 LRLQKEQLQRELEEKKKKEEQQRLAERQ 771
Score = 38.5 bits (88), Expect = 0.012
Identities = 22/70 (31%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Query: 316 EKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQ---EALEFESKR 372
EK+ RLE R +E E L RQ E + R + +LK+E++ ++ LQ + + ++
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 373 REQVEQALKQ 382
++Q+EQ Q
Sbjct: 596 KKQIEQKFAQ 605
Score = 37.4 bits (85), Expect = 0.027
Identities = 28/94 (29%), Positives = 54/94 (57%), Gaps = 8/94 (8%)
Query: 307 RIQEKQI-QQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTKRKLQEA 365
R QE+Q+ +QE++ + L ERE++E R+ A+ LQ + +Q+ L+++KK + + + A
Sbjct: 713 REQERQLAEQERRREQERLQAERELQE---REKALRLQ-KEQLQRELEEKKKKEEQQRLA 768
Query: 366 LEFESKRREQVEQALKQATTSDSGLRMLKDTGIP 399
E + +E+ E+ K+A + L + D P
Sbjct: 769 ---ERQLQEEQEKKAKEAAGASKALNVTVDVQSP 799
Score = 32.3 bits (72), Expect = 0.86
Identities = 20/80 (25%), Positives = 47/80 (58%), Gaps = 7/80 (8%)
Query: 307 RIQEKQIQQEKKELRLELYRER------EIRENLERQLA-VELQSRTTMQKRLKKEKKTK 359
R++E ++++E++ ++ RER E ++ +E++ A ++ ++ ++RL +EK K
Sbjct: 566 RLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK 625
Query: 360 RKLQEALEFESKRREQVEQA 379
+ + +E RR+Q E+A
Sbjct: 626 KAAAKKMEEVEARRKQEEEA 645
Score = 32.0 bits (71), Expect = 1.1
Identities = 23/95 (24%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 304 DNARIQEKQIQQEKKELRLELYREREIRENLE-RQLAVELQSRTTMQKRLKKEKKTKRKL 362
+ R ++ +Q++K+E + L + E + E R+ Q R ++R ++ ++ +R+
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714
Query: 363 QEALEFESKRREQVE--QALKQATTSDSGLRMLKD 395
QE E +RR + E QA ++ + LR+ K+
Sbjct: 715 QERQLAEQERRREQERLQAERELQEREKALRLQKE 749
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,037,622
Number of Sequences: 37866
Number of extensions: 949420
Number of successful extensions: 9421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 589
Number of HSP's that attempted gapping in prelim test: 6069
Number of HSP's gapped (non-prelim): 3285
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.