Guide to the Human Genome
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Search of human proteins with 21389613

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21389613 tektin 4 [Homo sapiens]
         (435 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21389613 tektin 4 [Homo sapiens]                                   869   0.0  
gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens]       718   0.0  
gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens]            534   e-152
gi|13994250 tektin 3 [Homo sapiens]                                   290   2e-78
gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens]       288   7e-78
gi|16753231 tektin 1 [Homo sapiens]                                   277   2e-74
gi|21389569 tektin 5 [Homo sapiens]                                   228   8e-60
gi|75677606 hypothetical protein LOC100132288 [Homo sapiens]          191   1e-48
gi|16507950 tektin 2 [Homo sapiens]                                   189   3e-48
gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens]            186   5e-47
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     51   2e-06
gi|21735548 centrosomal protein 2 [Homo sapiens]                       50   4e-06
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              49   7e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    49   1e-05
gi|169209613 PREDICTED: hypothetical protein LOC100128785 [Homo ...    47   3e-05
gi|169210642 PREDICTED: hypothetical protein LOC100128785 [Homo ...    47   3e-05
gi|169210176 PREDICTED: hypothetical protein LOC100128785 [Homo ...    47   3e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    46   6e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    46   6e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    46   6e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    46   6e-05
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                45   2e-04
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]                 44   2e-04
gi|4504063 golgin 97 [Homo sapiens]                                    44   3e-04
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    44   3e-04
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]           43   5e-04
gi|56550043 sarcolemma associated protein [Homo sapiens]               43   5e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    42   0.001
gi|112420968 coiled-coil domain containing 158 [Homo sapiens]          42   0.001
gi|38044112 restin isoform b [Homo sapiens]                            41   0.002

>gi|21389613 tektin 4 [Homo sapiens]
          Length = 435

 Score =  869 bits (2245), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MAQTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRD 60
           MAQTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRD
Sbjct: 1   MAQTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRD 60

Query: 61  QSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120
           QSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL
Sbjct: 61  QSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120

Query: 121 AQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKR 180
           AQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKR
Sbjct: 121 AQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKR 180

Query: 181 TIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESAS 240
           TIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESAS
Sbjct: 181 TIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESAS 240

Query: 241 TPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELE 300
           TPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELE
Sbjct: 241 TPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELE 300

Query: 301 DARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDA 360
           DARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDA
Sbjct: 301 DARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDA 360

Query: 361 AQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMA 420
           AQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMA
Sbjct: 361 AQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMA 420

Query: 421 HRTRYPTILQLAGYQ 435
           HRTRYPTILQLAGYQ
Sbjct: 421 HRTRYPTILQLAGYQ 435


>gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens]
          Length = 445

 Score =  718 bits (1854), Expect = 0.0
 Identities = 369/439 (84%), Positives = 392/439 (89%), Gaps = 13/439 (2%)

Query: 3   QTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQS 62
           QTVPP ELPCKEYDVARNTGAYTSSGLATA        LE WFQNCYARY QAFA+ +QS
Sbjct: 14  QTVPPYELPCKEYDVARNTGAYTSSGLATAX-------LEVWFQNCYARYRQAFANCNQS 66

Query: 63  ER--QRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120
           ER  Q HESQQLA ETQALAQ TQQDST  VGERLQDT+SWKSELQRE+EALAAET+LLL
Sbjct: 67  ERELQGHESQQLAAETQALAQPTQQDSTCRVGERLQDTNSWKSELQREVEALAAETDLLL 126

Query: 121 AQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKR 180
           AQKQRLERALDA EVPFSITTDN+QC +R +H NL+RDHVETELLKEAELIRNIQELLKR
Sbjct: 127 AQKQRLERALDAMEVPFSITTDNMQCSQRHQHTNLLRDHVETELLKEAELIRNIQELLKR 186

Query: 181 TIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQE--- 237
            IMQAVSQI LN EH E CEMDWSDK+EAYN+D+TCGRHHSQSTEVQAHP+STTFQE   
Sbjct: 187 AIMQAVSQIXLNXEHMEICEMDWSDKVEAYNLDKTCGRHHSQSTEVQAHPHSTTFQERGP 246

Query: 238 -SASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRC 296
            SASTPETR KFTQDNLC AQRERL SANL VLVDCILRDTSEDL LQCDAVNLAFGRRC
Sbjct: 247 RSASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRC 306

Query: 297 EELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMEL 356
           EELEDAR+KL HHLHK LREITDQEHNV ALK+AIKDKE PLH+AQTRL L SHRPNM+L
Sbjct: 307 EELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRLXLLSHRPNMQL 366

Query: 357 CRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQ 416
           CRDAAQFRL+SEVEEL  S+TALREKLL+AEQSLRNL+DIHMSLEKD+ AMTNS+FIDRQ
Sbjct: 367 CRDAAQFRLVSEVEELYKSITALREKLLQAEQSLRNLKDIHMSLEKDVTAMTNSVFIDRQ 426

Query: 417 KCMAHRTRYPTILQLAGYQ 435
           KCMAHRT YPTILQLAGYQ
Sbjct: 427 KCMAHRTCYPTILQLAGYQ 445


>gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens]
          Length = 507

 Score =  534 bits (1375), Expect = e-152
 Identities = 316/541 (58%), Positives = 338/541 (62%), Gaps = 155/541 (28%)

Query: 3   QTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQS 62
           QTVPPCELPCKEYDVA                                     FAD +QS
Sbjct: 14  QTVPPCELPCKEYDVA-------------------------------------FADCNQS 36

Query: 63  ER--QRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120
           ER  Q H+SQQLA E QALAQ TQQDS   VGERLQD HSW SELQ E+EALAAET+LLL
Sbjct: 37  ERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLL 96

Query: 121 AQKQRLERALDATEVPFSITTDNLQ----------------------------------C 146
           AQKQRLE ALDA EVPFSI TDN+Q                                  C
Sbjct: 97  AQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQCLKNCC 156

Query: 147 RERR------------------EHPNLVRDHVETELL---KEAELIRNIQELLKRTIMQA 185
             R+                  E  N   +   T  L   +EAELIRNIQELLKR I+QA
Sbjct: 157 SSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQA 216

Query: 186 VSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETR 245
           VSQIRLNREH E CEMDWSDK+EAYN+DETCGRH SQSTE +          SASTPETR
Sbjct: 217 VSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTEPR----------SASTPETR 266

Query: 246 AKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYK 305
            KFTQDNLCRAQRERL SANL VLVDCILRDTSEDL LQCDAVNLAFGRRCEELEDAR+K
Sbjct: 267 TKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELEDARHK 326

Query: 306 LHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFR- 364
           L HHL K LREITDQEHN+ ALK+AIKDKEAPLH+AQTRLYL SHRPNMELCRDAAQFR 
Sbjct: 327 LQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNMELCRDAAQFRY 386

Query: 365 --------------------------------------------------LLSEVEELNM 374
                                                             L+SE+EEL  
Sbjct: 387 RHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKLVSELEELYK 446

Query: 375 SLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGY 434
           S+TAL EKLL+AEQSL NLEDIHMSLEKD+ AMTNSLF+DRQ CMAH T YPTILQLAGY
Sbjct: 447 SITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMTNSLFLDRQNCMAHHTCYPTILQLAGY 506

Query: 435 Q 435
           Q
Sbjct: 507 Q 507


>gi|13994250 tektin 3 [Homo sapiens]
          Length = 490

 Score =  290 bits (742), Expect = 2e-78
 Identities = 160/398 (40%), Positives = 242/398 (60%)

Query: 37  SKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQ 96
           ++Y  ++W+++    Y ++   R  SE+ R ++ +L  +     ++TQ D+T+ +GER+ 
Sbjct: 92  TRYTPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVN 151

Query: 97  DTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLV 156
           D   WKSE+  E++ +  ETN L   K+RLERAL  TE P  +  + L  RE+R   +LV
Sbjct: 152 DIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLV 211

Query: 157 RDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETC 216
            D VE +LL E + I   QE +K  + +A++Q+  NR  +   E D SDK  AY ID+ C
Sbjct: 212 HDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKC 271

Query: 217 GRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRD 276
               + S  V           + S PE+ AKFT DN+ R+Q ER ASA LR  ++ +L  
Sbjct: 272 HHLRNTSDGVGYFRGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVV 331

Query: 277 TSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEA 336
           T+ ++  Q + VNL+F  R  E  DA+ K+  HL KTL+EI   E  + ++K+AIKDK A
Sbjct: 332 TANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTA 391

Query: 337 PLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDI 396
            L VAQTRL  R+ RPN+ELCRD AQ RL++EV E++ ++  L+++L +AE +L++L  I
Sbjct: 392 FLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTLQQRLRDAEDTLQSLVHI 451

Query: 397 HMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGY 434
             +LE D+A   NSL+ID++KCM+ R  YP  L+L G+
Sbjct: 452 KATLEYDLAVKANSLYIDQEKCMSMRKSYPNTLRLVGF 489


>gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens]
          Length = 333

 Score =  288 bits (737), Expect = 7e-78
 Identities = 163/283 (57%), Positives = 184/283 (65%), Gaps = 64/283 (22%)

Query: 5   VPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQSER 64
           +PPCELPCKEYDVARNTG Y SSGLATA        LE WFQNCYARYHQAFA+ +QSE+
Sbjct: 1   MPPCELPCKEYDVARNTGTYMSSGLATAX-------LEVWFQNCYARYHQAFANCNQSEQ 53

Query: 65  --QRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQ 122
             Q HESQQLA ETQALAQ TQQDSTR VGE+LQDTHSWKSELQRE+EALAAET+LLLAQ
Sbjct: 54  ELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQ 113

Query: 123 KQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLK-----EAELIRNIQEL 177
           KQRLE ALDATE PFSI TDNLQC +  +H NL+RDHVETELLK      ++ + N    
Sbjct: 114 KQRLEHALDATEAPFSIATDNLQCSQGHQHANLMRDHVETELLKAHPPAPSQCLNNCFSS 173

Query: 178 LKRTI-----MQAVSQIRLNRE--------------HKETCEM----------------- 201
            K +       Q +  + +  E              HK+  E+                 
Sbjct: 174 RKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAVS 233

Query: 202 --------------DWSDKMEAYNIDETCGRHHSQSTEVQAHP 230
                         DWSDK+EAYN+DETCGRHHSQSTEVQAHP
Sbjct: 234 QIRLNREHTEICEMDWSDKVEAYNLDETCGRHHSQSTEVQAHP 276


>gi|16753231 tektin 1 [Homo sapiens]
          Length = 418

 Score =  277 bits (708), Expect = 2e-74
 Identities = 155/389 (39%), Positives = 229/389 (58%)

Query: 38  KYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQD 97
           K+L  EW      +YH+A A R +SER   ESQ+L  E +   +++Q D  + + +RL++
Sbjct: 10  KFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEE 69

Query: 98  THSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVR 157
              WK EL  ++E L   T+ LL  K RLE+AL+  + P  IT   L  RE+R   +LV 
Sbjct: 70  VQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVH 129

Query: 158 DHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCG 217
           D VE EL+KEAE+I+ I  LL RT+ +A  QIR+NR  K   E D  DK  A  ID+ C 
Sbjct: 130 DTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICF 189

Query: 218 RHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDT 277
             ++ S  ++    +   + ++ + E    F+  N+ +A ++R  S  L+ LVD IL  T
Sbjct: 190 SLNNNSPNIRYSENAVRIEPNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQT 249

Query: 278 SEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAP 337
           + DLR QCD V+ AF    ++ +DAR KL  HL K + EI  QE N+ AL++AI D+E P
Sbjct: 250 ANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGP 309

Query: 338 LHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIH 397
             VA TRL  R+HRPN+ELCRD AQ+RL+ EV+E+  ++  L+E L +A+  L+ L    
Sbjct: 310 AKVAHTRLETRTHRPNVELCRDVAQYRLMKEVQEITHNVARLKETLAQAQAELKGLHRRQ 369

Query: 398 MSLEKDIAAMTNSLFIDRQKCMAHRTRYP 426
           ++L+++I    N+++ID   CM  R   P
Sbjct: 370 LALQEEIQVKENTIYIDEVLCMQMRKSIP 398


>gi|21389569 tektin 5 [Homo sapiens]
          Length = 485

 Score =  228 bits (581), Expect = 8e-60
 Identities = 138/398 (34%), Positives = 210/398 (52%)

Query: 37  SKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQ 96
           S+Y   +W Q+   +   A A R  + R   +S +L  +   L  + Q+ + R +G+RL 
Sbjct: 87  SRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLS 146

Query: 97  DTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLV 156
           D   WKSEL  E++ L  E   L   K+RLE A +    P  +  + L  RE+R   +LV
Sbjct: 147 DIGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLV 206

Query: 157 RDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETC 216
            D+VE  L++E +L++  QE +++   +   Q+R NR+ +   E D  DK  A  IDE C
Sbjct: 207 HDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKC 266

Query: 217 GRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRD 276
               + S  +           + S PET AKF+ DN+  +Q  R  S  LR   + +   
Sbjct: 267 FNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFET 326

Query: 277 TSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEA 336
            S+ +  Q    NLAF  R  E+ D + KL   L KTL+EI   E+ +  L+++I  KE 
Sbjct: 327 LSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEG 386

Query: 337 PLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDI 396
           PL VAQTRL  R+ RPNMELCRD  Q +L++EV  ++ +L  L+ +L E + +L+ L   
Sbjct: 387 PLKVAQTRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMT 446

Query: 397 HMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGY 434
              LE ++A   N+L ID++KCM  R  +P   +L G+
Sbjct: 447 KCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGH 484


>gi|75677606 hypothetical protein LOC100132288 [Homo sapiens]
          Length = 129

 Score =  191 bits (485), Expect = 1e-48
 Identities = 95/108 (87%), Positives = 98/108 (90%)

Query: 238 SASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCE 297
           SASTPETR KFTQDNLC AQRERL SANL VLVDCILRDTSEDL LQCDAVNLAFG RCE
Sbjct: 22  SASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGCRCE 81

Query: 298 ELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRL 345
           ELEDAR+KL HHLHK LREITDQEHNV ALK+AIKDKE PLH+AQTRL
Sbjct: 82  ELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRL 129


>gi|16507950 tektin 2 [Homo sapiens]
          Length = 430

 Score =  189 bits (481), Expect = 3e-48
 Identities = 123/397 (30%), Positives = 201/397 (50%), Gaps = 2/397 (0%)

Query: 29  LATASFRTSK-YLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDS 87
           +AT S + S+ + L +W  N Y     A   RD S + R E++ L  ET       + D+
Sbjct: 1   MATLSVKPSRRFQLPDWHTNSYLLSTNAQLQRDASHQIRQEARVLRNETNNQTIWDEHDN 60

Query: 88  TRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCR 147
              + ER+   + WK  L + +  L AE + L   K+  E+ L A  +P  +  + L  R
Sbjct: 61  RTRLVERIDTVNRWKEMLDKCLTDLDAEIDALTQMKESAEQNLQAKNLPLDVAIECLTLR 120

Query: 148 ERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKM 207
           E R   ++V+D VE EL KE E+I   ++ L++ + QA  Q+ L +E ++    D   KM
Sbjct: 121 ESRRDIDVVKDPVEDELHKEVEVIEATKKALQQKVSQAFEQLCLLQEVQQQLNSDHRGKM 180

Query: 208 EAYNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLR 267
           E   ID  C   + +S  +      T   + ++T +    F++ N  RA+ E  A+  LR
Sbjct: 181 ETLEIDRGCLSLNLRSPNISLKVDPTRVPDGSTTLQQWDDFSRFNKDRAEAEMKAATELR 240

Query: 268 VLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAAL 327
                 + +T+ +L  Q  A   AF +R  E+E    +L      TL EI + + ++  L
Sbjct: 241 EATALTIAETNNELEAQRVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHL 300

Query: 328 KQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAE 387
           ++ ++ K   L ++ TRL  R++RPN+ELCRD AQ+ L  EV +L  ++ AL++KL +A+
Sbjct: 301 EEDLRTKLLSLKLSHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQ 360

Query: 388 QSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAHRTR 424
            +L  L      L+ DIA   NS+ +D  KCM  R +
Sbjct: 361 DALDALCKHLARLQADIACKANSMLLD-TKCMDTRRK 396


>gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens]
          Length = 254

 Score =  186 bits (471), Expect = 5e-47
 Identities = 104/166 (62%), Positives = 114/166 (68%), Gaps = 40/166 (24%)

Query: 3   QTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQS 62
           QT+PPCELPCKEYD                                      AFA+ +QS
Sbjct: 14  QTMPPCELPCKEYD--------------------------------------AFANCNQS 35

Query: 63  ER--QRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120
           ER  Q HESQQLA ETQALAQ TQQDSTR VGE+LQDTHSWKSELQRE+EALAAET+LLL
Sbjct: 36  ERELQGHESQQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLL 95

Query: 121 AQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLK 166
           AQKQRLE ALDATE PFSI TDNLQC +  ++ NL+RDHVETELLK
Sbjct: 96  AQKQRLEHALDATEAPFSIATDNLQCSQGHQNANLMRDHVETELLK 141


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 82/347 (23%), Positives = 141/347 (40%), Gaps = 52/347 (14%)

Query: 61   QSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120
            + E  +   +QLA E +     T Q        +LQ+    ++EL  E E L A    L 
Sbjct: 851  EEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR---LT 907

Query: 121  AQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKR 180
            A+KQ LE               +L+ R   E       H++ E   + ++ +NIQEL ++
Sbjct: 908  AKKQELEE-----------ICHDLEARVEEEEERC--QHLQAE---KKKMQQNIQELEEQ 951

Query: 181  TIMQAVSQIRLNREHKETCEMDWSDKMEAYNI---DETCGRHHSQSTEVQAHPYSTTFQE 237
               +  ++ +L  E K T E     K+E   I   D+ C                   +E
Sbjct: 952  LEEEESARQKLQLE-KVTTEAKLK-KLEEEQIILEDQNC----------------KLAKE 993

Query: 238  SASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCE 297
                 +  A+FT  NL   + +  + A L+   + ++ D  E LR +         ++ +
Sbjct: 994  KKLLEDRIAEFT-TNLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE--------EKQRQ 1044

Query: 298  ELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELC 357
            ELE  R KL         +I + +  +A LK  +  KE  L  A  R+   + + NM L 
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104

Query: 358  RDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDI 404
            +      L S++ EL   L + R    +AE+  R+L +   +L+ ++
Sbjct: 1105 KIR---ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 69/377 (18%), Positives = 152/377 (40%), Gaps = 47/377 (12%)

Query: 75   ETQALAQRTQQDSTRT--VGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLERALDA 132
            E QA   R ++++ +     +++++  S  SELQ ++E+  A  N    QK+ L   L+A
Sbjct: 1084 ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEA 1143

Query: 133  TEVPFSITTDNLQCRE-----RREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVS 187
             +     T D+   ++     R +  N+++  +E E       I+ +++   + + +   
Sbjct: 1144 LKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAE 1203

Query: 188  QIRLNREHKETCEM----------DWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQE 237
            Q+   +  K   E           + +++++     +    H  +  E Q       F E
Sbjct: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263

Query: 238  ------SASTPETRAKFTQDNL--CRAQRERLASANLR--VLVDCILRDTSEDLRLQCDA 287
                    +   T+ +   DN+    +Q +  +S   +    ++  L+DT E L+ + + 
Sbjct: 1264 GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEE-NR 1322

Query: 288  VNLAFGRRCEELEDARYKLHHHL-------HKTLREITDQEHNVAALKQAIKDKEAPLHV 340
              L+   + +++ED +      L       H   ++I      VA +K+ ++D    L  
Sbjct: 1323 QKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLET 1382

Query: 341  A-------QTRLYLRSHRPNMELCR----DAAQFRLLSEVEELNMSLTALREKLLEAEQS 389
            A       Q  L   S R   ++      +  + RL  E+++L + L   R+     E+ 
Sbjct: 1383 AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKK 1442

Query: 390  LRNLEDIHMSLEKDIAA 406
             +  + + ++ EK I+A
Sbjct: 1443 QKKFDQL-LAEEKTISA 1458



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 80/370 (21%), Positives = 145/370 (39%), Gaps = 47/370 (12%)

Query: 63   ERQRHESQQLATETQALA-QRTQQDSTRTVGE----------RLQDTHSWKS-------E 104
            ER R E++    ET+AL+  R  +++     E           ++D  S K        E
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522

Query: 105  LQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLV-RDHVETE 163
            L++   AL  +   +  Q + LE  L ATE        NLQ  + +   +L  RD    E
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582

Query: 164  LLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAY------NIDETCG 217
              K+ +L+R ++E ++  +     Q  +    ++  EMD  D +EA+      N DE   
Sbjct: 1583 --KKKQLVRQVRE-MEAELEDERKQRSMAVAARKKLEMDLKD-LEAHIDSANKNRDEAI- 1637

Query: 218  RHHSQSTEVQAHPYSTTFQESASTPE---TRAKFTQDNLCRAQRERLASANLRVLVDCIL 274
                +  + Q         ++ ++ E    +AK  +  L   + E +         +   
Sbjct: 1638 -KQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAK 1696

Query: 275  RDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDK 334
            R   ++     D +  + G+    LE+ R +L   + +   E+ +++ N   +   +K  
Sbjct: 1697 RQAQQERDELADEIANSSGKGALALEEKR-RLEARIAQLEEELEEEQGNTELINDRLKKA 1755

Query: 335  EAPLHVAQTRLYL-RSHRPNMELCRDAAQFR------LLSEVE-----ELNMSLTALREK 382
               +    T L L RSH    E  R   + +       L E+E     +   S+TAL  K
Sbjct: 1756 NLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK 1815

Query: 383  LLEAEQSLRN 392
            + + E+ L N
Sbjct: 1816 IAQLEEQLDN 1825



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 77/368 (20%), Positives = 147/368 (39%), Gaps = 36/368 (9%)

Query: 64   RQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQK 123
            + +HE+     E +   +  Q+        +L+   +  S+   E++A  AE  + LA+K
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081

Query: 124  QR-LERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTI 182
            +  L+ AL   E        N+  ++ RE  + + +  E   L+     RN  E  KR +
Sbjct: 1082 EEELQAALARVEE--EAAQKNMALKKIRELESQISELQED--LESERASRNKAEKQKRDL 1137

Query: 183  MQAVSQIRLNREH---KETCEMDWSDKMEAY------NIDETCGRHHSQSTEVQAHPYST 233
             + +  ++   E        + +   K E         ++E    H +Q  E++   +S 
Sbjct: 1138 GEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMR-QKHSQ 1196

Query: 234  TFQESASTPETRAKFTQDNLCRAQR----ERLASAN-LRVLV----DCILRDTSEDLRLQ 284
              +E A   E + K  + NL +A++    ER   AN ++VL+    D   +    + +LQ
Sbjct: 1197 AVEELAEQLE-QTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQ 1255

Query: 285  CDAVNLAFGRRCE-ELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQT 343
               V    G R   EL D   KL   L      ++  +   + L +     E+ L   Q 
Sbjct: 1256 ELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQE 1315

Query: 344  RLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKD 403
             L   + +          +  L ++++++     + RE+L E E++  NLE    +L   
Sbjct: 1316 LLQEENRQ----------KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQ 1365

Query: 404  IAAMTNSL 411
            +A M   +
Sbjct: 1366 VADMKKKM 1373


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 88/395 (22%), Positives = 158/395 (40%), Gaps = 54/395 (13%)

Query: 61   QSERQRHESQQLATETQALAQRTQQDS----TRTVGERLQDTHSWKSEL-----QREMEA 111
            +SER+R ++ Q   E +    +  Q++    T+T+ ER ++  + + ++     QREM+ 
Sbjct: 1396 ESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQK 1455

Query: 112  LA------------AETNLLLAQKQRLERALDATE-VPFSI-------TTDNLQCRE--- 148
             A             E +L   Q Q LE+     E +P ++       T    Q RE   
Sbjct: 1456 AALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEK 1515

Query: 149  RREHPNLVRDHVETELLKEAELIRN----IQELLKRTIMQAVSQIRL-NREHKETCEMDW 203
             RE    V +H   EL K+ ++I +    +Q+L K+ +      + L    HK  C+   
Sbjct: 1516 DRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKL 1575

Query: 204  SDKMEAYNIDETCGRHH------SQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQ 257
              ++E     +     H       +S E+QA        ES ST   R    +D   ++Q
Sbjct: 1576 IKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ 1635

Query: 258  RERLASANLR---VLVDCILRDTSEDLRLQCDAVNLAFGRRCEE---LEDARYKLHHHLH 311
            RE++     +   +  D   RD  ++L LQ + + +   +R  +   LE+   ++   L 
Sbjct: 1636 REQIEELQRQKEHLTQDLERRD--QELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLR 1693

Query: 312  KTLREITDQEHNVAALKQAIK--DKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEV 369
            +  RE+T Q   +    +  K   K     +   +L LR     +E C+      L    
Sbjct: 1694 ERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVE-CQQEHIHELQELK 1752

Query: 370  EELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDI 404
            ++L   L  L  K+ E    L   E   + L++ +
Sbjct: 1753 DQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQL 1787



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 72/327 (22%), Positives = 138/327 (42%), Gaps = 32/327 (9%)

Query: 85   QDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLE---RALDATEVPFSITT 141
            +D  + + ERL DT + KS++  E++ L  + +    +K + E    +L++  +    T 
Sbjct: 1263 RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETM 1322

Query: 142  DNLQCRERREHPNLVRDHVETELLKEAELIRNIQ-ELLKRTIMQAVSQIR---LNREHKE 197
             +LQ R RR     +    E ELL+ A+     Q E L+  +++A +Q     +  E   
Sbjct: 1323 ASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLR 1382

Query: 198  TCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQD-NLCRA 256
            T       K E    +    +   +  E++        +  A   +T A+  ++    R 
Sbjct: 1383 TARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRG 1442

Query: 257  QRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLRE 316
            Q + L     R +    L   S DL+ +   V+L    + +ELE  R  L H        
Sbjct: 1443 QIQELEKQ--REMQKAALELLSLDLKKRNQEVDLQ-QEQIQELEKCRSVLEH-------- 1491

Query: 317  ITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSL 376
                      L  A++++E  L V   R  +R    + E  R+  + +LL E+E+ +  +
Sbjct: 1492 ----------LPMAVQEREQKLTV--QREQIRELEKDRETQRNVLEHQLL-ELEKKDQMI 1538

Query: 377  TALREKLLEAEQSLRNLEDIHMSLEKD 403
             + R ++ + ++ L  LE + + LE++
Sbjct: 1539 ESQRGQVQDLKKQLVTLECLALELEEN 1565



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 74/351 (21%), Positives = 132/351 (37%), Gaps = 43/351 (12%)

Query: 58   DRDQSERQRHES-QQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAET 116
            +R Q+E++R  + +QLA   Q      +Q       E  Q    W+ E     + LA   
Sbjct: 818  ERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKAL 877

Query: 117  NLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQE 176
              L  +K  LE  L   +       + +Q +   E         + +L  E E +  ++ 
Sbjct: 878  ESLEREKMELEMRLKEQQTEM----EAIQAQREEERTQAESALCQMQLETEKERVSLLET 933

Query: 177  LLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQ 236
            LL+     A +  +L R  ++        K++     ET G               T  Q
Sbjct: 934  LLQTQKELADASQQLERLRQDM-------KVQKLKEQETTG------------ILQTQLQ 974

Query: 237  ESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRC 296
            E+    +  A+  +D+L   Q E  +    ++ +   + D    L  Q D+  L      
Sbjct: 975  EAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQ 1034

Query: 297  EELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMEL 356
            E+L + +   ++ + K L      E   A+L  ++ +KE  L V Q    +R  +  +  
Sbjct: 1035 EKLRETQE--YNRIQKEL------EREKASLTLSLMEKEQRLLVLQEADSIR--QQELSA 1084

Query: 357  CRDAAQFRLLSEVEELNMSLTALREKLLEAE--------QSLRNLEDIHMS 399
             R   Q     E +EL+  +  LR+++ E E        Q L  LE  H++
Sbjct: 1085 LRQDMQ-EAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHIT 1134



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 37/167 (22%), Positives = 74/167 (44%), Gaps = 28/167 (16%)

Query: 45   FQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSE 104
            +Q    +  QA A RD+  R + E +QL    ++LAQR Q++    + E+       + E
Sbjct: 2033 YQEDVQQLQQALAQRDEELRHQQEREQLL--EKSLAQRVQEN---MIQEKQNLGQEREEE 2087

Query: 105  LQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPN---LVRDHVE 161
              R +     E  L LAQK++                + L+ RE ++  N   L   H  
Sbjct: 2088 EIRGLHQSVRELQLTLAQKEQ----------------EILELRETQQRNNLEALPHSHKT 2131

Query: 162  TELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKME 208
            + + +++  + +++  L+R + +  + +R      E  E++W +K +
Sbjct: 2132 SPMEEQSLKLDSLEPRLQRELERLQAALR----QTEAREIEWREKAQ 2174



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 56/349 (16%), Positives = 134/349 (38%), Gaps = 17/349 (4%)

Query: 61   QSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120
            +++R   E Q L  E +     +Q+   + + ++L        EL+     +  +  L+ 
Sbjct: 1518 ETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLI- 1576

Query: 121  AQKQRLERALDATEVPFSITTDNLQCR--ERREHPNLVRDHVETELLKEAELIRNIQELL 178
               + LE   +   V  +  T +L+ R  E +   + + D      +   EL    QE+ 
Sbjct: 1577 ---KELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEV- 1632

Query: 179  KRTIMQAVSQIRLNREHK----ETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTT 234
             ++  + + +++  +EH     E  + +   + E   + E      ++  E        +
Sbjct: 1633 -KSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLS 1691

Query: 235  FQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGR 294
             +E      T+ +  Q+     +    A       +  ILRD  +++  Q + ++     
Sbjct: 1692 LRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIH-ELQE 1750

Query: 295  RCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNM 354
              ++LE     LH  + +T   ++ +E  +  L+Q +++      + +  L  +      
Sbjct: 1751 LKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQR 1810

Query: 355  ELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRN-LEDIHMSLEK 402
             L +   +   L + ++         E++ E   +L+  LE  HM+L++
Sbjct: 1811 ALAQRDQELEALQQEQQ---QAQGQEERVKEKADALQGALEQAHMTLKE 1856


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 85/403 (21%), Positives = 166/403 (41%), Gaps = 62/403 (15%)

Query: 36  TSKYLLEEWFQNCYARYHQAFADRD----QSERQRHESQQLATETQALAQRTQQDSTRTV 91
           T K  LE+  +      +Q+   R+    Q E  R +  +   + + L  +  Q S +  
Sbjct: 279 TEKNQLEQELELSRRLLNQSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQISKQQS 338

Query: 92  GERLQDTHSWKSE--LQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRER 149
             + +    W+    ++RE + L  + + L  Q      A +  EV         +C ER
Sbjct: 339 NYQDEQGEDWRFRRGVEREKQDLEKQMSDLRVQLNFSAMASELEEVK--------RCMER 390

Query: 150 REHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEA 209
           +       D  +  L  + E +    E  ++  +Q + +++  + H +TCE +   K   
Sbjct: 391 K-------DKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAE--RKHAD 441

Query: 210 YNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVL 269
             I E     H++    QA  Y +  Q+S +  E   K  +D   +AQ E +    L+  
Sbjct: 442 LQISELT--RHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQ-ESIRQWKLK-- 496

Query: 270 VDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITD--QEHNVAAL 327
                +     L  Q + V+   G+  + L++ + +L   L+  L++I +  +E N    
Sbjct: 497 ----HKKLERALEKQSETVDELTGKNNQILKE-KDELKTQLYAALQQIENLRKELNDVLT 551

Query: 328 KQAIKDKEAPLHVAQTRLY-LRSHRPNMEL-------------------CRDAAQFR--- 364
           K+A++++E  LH  + +L  ++SH+ ++EL                    +  +Q +   
Sbjct: 552 KRALQEEE--LHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKIQSQMKVEK 609

Query: 365 --LLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIA 405
             L  E+ EL  S    + KLLE ++S+++L  I   L   +A
Sbjct: 610 AHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLA 652


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 73/395 (18%), Positives = 152/395 (38%), Gaps = 36/395 (9%)

Query: 57   ADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERL-------QDTHSWKSELQREM 109
            A+  +  R   E+      T A  ++ Q DS   +GE++       Q     KSEL+ E+
Sbjct: 1173 AEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEI 1232

Query: 110  EALAAETNLLLAQKQRLERALDATEVPFS-ITTDNLQCRERREHPNLVRDHVETELLKEA 168
            + +A+    L   K  +ER     E  FS I   + Q  +     N+ +  ++T+  + +
Sbjct: 1233 DDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELS 1292

Query: 169  ELIRNIQELL------KRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNID-ETCGRHHS 221
              +   + L+      K+ + Q + +++   E +   +   +  +++   D +     + 
Sbjct: 1293 HRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYE 1352

Query: 222  QSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDL 281
            +  E +A       + ++   + R K+  D + R +    A   L   +     + +E  
Sbjct: 1353 EEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ-EAEENTETA 1411

Query: 282  RLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHN----VAALKQAIKDKEAP 337
              +C ++     R   E+ED    L    H     +  ++ N    +A  KQ + + +A 
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERS-HTACATLDKKQRNFDKVLAEWKQKLDESQAE 1470

Query: 338  LHVAQTRLYLRSHRPNMELCRDAAQ-------------FRLLSEVEELNMSLTALREKLL 384
            L  AQ     RS    +   R+A +               L  E+ +L   +    + L 
Sbjct: 1471 LEAAQKE--SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQ 1528

Query: 385  EAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCM 419
            EAE++ + +E     L+  +  +  SL  +  K +
Sbjct: 1529 EAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKIL 1563



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 77/381 (20%), Positives = 155/381 (40%), Gaps = 53/381 (13%)

Query: 69   SQQLATETQALAQRTQQ--DSTRTVGERLQDTHSWKSELQREMEALAAETN--------- 117
            +++L    + LAQR Q+  ++T T   +       K  LQ E+E L  +           
Sbjct: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446

Query: 118  ---------LLLAQKQRLERA---LDATEVPF-SITTDNLQCRERREHPNLVRDHVETEL 164
                     +L   KQ+L+ +   L+A +    S++T+  + R   E    V D +ET  
Sbjct: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEE---VVDQLETLR 1503

Query: 165  LKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQST 224
             +   L   I +L ++ I +    ++   + K+  E + SD   A  ++E  G    + +
Sbjct: 1504 RENKNLQEEISDLTEQ-IAETGKNLQEAEKTKKLVEQEKSDLQVA--LEEVEGSLEHEES 1560

Query: 225  EVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQ 284
            ++       +  +S    +   K  +    +   +R A A L+ ++D  +R  ++ LRL+
Sbjct: 1561 KILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEA-LQSVLDAEIRSRNDALRLK 1619

Query: 285  CDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTR 344
                        +++E    ++   L  + R++ + + ++  ++  +KD +  L  A   
Sbjct: 1620 ------------KKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDA--- 1664

Query: 345  LYLRSHRPNMELCR--DAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEK 402
              LRS+    E     +     LL E+EE+ ++L         +EQ L +  D    L  
Sbjct: 1665 --LRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS 1722

Query: 403  DIAAMTNS---LFIDRQKCMA 420
               ++ N+   L  D  +C A
Sbjct: 1723 QNTSLINTKKKLEADIAQCQA 1743


>gi|169209613 PREDICTED: hypothetical protein LOC100128785 [Homo
           sapiens]
          Length = 639

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 25/42 (59%), Positives = 29/42 (69%)

Query: 125 RLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLK 166
           +L  A D   VPFSI T+NLQ  E+  HP LV D+VETELLK
Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLK 344



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 30/59 (50%), Positives = 33/59 (55%), Gaps = 5/59 (8%)

Query: 344 RLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEK 402
           RL LR    N   C      RL +EVE L+ SL  LREKLLE EQSL NLE +    EK
Sbjct: 431 RLALRQDMDNSWGCP-----RLGNEVEGLHASLVVLREKLLEVEQSLGNLEYVQEPGEK 484


>gi|169210642 PREDICTED: hypothetical protein LOC100128785 [Homo
           sapiens]
          Length = 639

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 25/42 (59%), Positives = 29/42 (69%)

Query: 125 RLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLK 166
           +L  A D   VPFSI T+NLQ  E+  HP LV D+VETELLK
Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLK 344



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 30/59 (50%), Positives = 33/59 (55%), Gaps = 5/59 (8%)

Query: 344 RLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEK 402
           RL LR    N   C      RL +EVE L+ SL  LREKLLE EQSL NLE +    EK
Sbjct: 431 RLALRQDMDNSWGCP-----RLGNEVEGLHASLVVLREKLLEVEQSLGNLEYVQEPGEK 484


>gi|169210176 PREDICTED: hypothetical protein LOC100128785 [Homo
           sapiens]
          Length = 639

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 25/42 (59%), Positives = 29/42 (69%)

Query: 125 RLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLK 166
           +L  A D   VPFSI T+NLQ  E+  HP LV D+VETELLK
Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLK 344



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 30/59 (50%), Positives = 33/59 (55%), Gaps = 5/59 (8%)

Query: 344 RLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEK 402
           RL LR    N   C      RL +EVE L+ SL  LREKLLE EQSL NLE +    EK
Sbjct: 431 RLALRQDMDNSWGCP-----RLGNEVEGLHASLVVLREKLLEVEQSLGNLEYVQEPGEK 484


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 96/451 (21%), Positives = 174/451 (38%), Gaps = 74/451 (16%)

Query: 38   KYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQD 97
            K LL+E  Q     Y +A   R +   ++ E +++  E +A  +  +    +   ER + 
Sbjct: 889  KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 948

Query: 98   THSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTD--NLQCRERREHPNL 155
                  +L+ ++E   A    L  +K   E  +   E    +  D  N   +ER+     
Sbjct: 949  AQQML-DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 1007

Query: 156  VRDHVETELLKEAELIRNIQELL-KRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDE 214
            + D + T L +E E  +N+ +L  K   M +  ++RL +E K   E++   +     ++ 
Sbjct: 1008 ISD-LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR----KLEG 1062

Query: 215  TCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCIL 274
                 H Q  ++QA       Q +    E +A   + +   AQ+   A   +R L   I 
Sbjct: 1063 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNN-ALKKIRELEGHI- 1120

Query: 275  RDTSEDLRLQCDAVNLAFGRRC---EELEDARYKLHHHLHKTLREI---TDQEHNVAALK 328
             D  EDL  +  A N A  ++    EELE  + +L   L  T  +      +E  V  LK
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1180

Query: 329  QAIKDKEAPLHVAQTRLYLRSHRPNMELCRD--------------------------AAQ 362
            +A+ D+E   H AQ +   + H   +E   +                          A +
Sbjct: 1181 KAL-DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1239

Query: 363  FRLLSEVEE--------LNMSLTALREKLLEAEQSLRNLED-IH---------------- 397
             R+L + ++        L   +  L+ K  + E++   L D +H                
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299

Query: 398  ----MSLEKDIAAMTNSLFIDRQKCMAHRTR 424
                + L KD+A++++ L  D Q+ +   TR
Sbjct: 1300 EGKAIKLAKDVASLSSQL-QDTQELLQEETR 1329



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 76/381 (19%), Positives = 152/381 (39%), Gaps = 40/381 (10%)

Query: 64   RQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQK 123
            + +HES     E +   +   +     +  +L+   S   E   +++A  AE  + LA+K
Sbjct: 1029 KNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKK 1088

Query: 124  QR-LERALDATEVPFSITTDNLQ-CRERREHPNLVRDHVETELL------KEAELIRNIQ 175
            +  L+ AL   +   +   + L+  RE   H + +++ +++E        K+   +    
Sbjct: 1089 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148

Query: 176  ELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEV-QAHPYSTT 234
            E LK  +   +      +E +   E + +   +A  +DE    H +Q  E+ Q H  +  
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKREQEVTVLKKA--LDEETRSHEAQVQEMRQKHAQAVE 1206

Query: 235  FQESASTPETRAKFTQDNLCRAQRERLA--SANLRVLVDCILRDTSEDLRLQCDAVNLAF 292
                      RAK   D   +   +  A  +  LRVL         +  +L+     L  
Sbjct: 1207 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ- 1265

Query: 293  GRRCEELEDARYKLHHHLHKTLREITDQE--------------HNVAALKQAIKDKEAPL 338
              +C + E AR +L+  +HK   E+                   +VA+L   ++D +  L
Sbjct: 1266 -SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324

Query: 339  HV-AQTRLYLRSHRPNMELCRDAAQFRLLSEVEE----------LNMSLTALREKLLEAE 387
                + +L + +    +E  R++ Q +L  E+E           LN+ L+  ++KL +  
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1384

Query: 388  QSLRNLEDIHMSLEKDIAAMT 408
             ++  LE+     +K+I  +T
Sbjct: 1385 STVEALEEGKKRFQKEIENLT 1405



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 77/379 (20%), Positives = 139/379 (36%), Gaps = 56/379 (14%)

Query: 63   ERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKS------------------E 104
            ER R E++    ET+AL+     +      E L+ T+                      E
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529

Query: 105  LQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNL-VRDHVETE 163
            L++   AL  +   +  Q + LE  L ATE        N+Q  + +   +L  RD    E
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589

Query: 164  LLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHS-- 221
              K  +L R + E  +  +     Q  L    K+  E D  D +E        GR  +  
Sbjct: 1590 --KRRQLQRQLHE-YETELEDERKQRALAAAAKKKLEGDLKD-LELQADSAIKGREEAIK 1645

Query: 222  --QSTEVQAHPYSTTFQE----------SASTPETRAKFTQDNLCRAQRERLASANLRVL 269
              +  + Q   +    ++          +A   E +AK  + +L + Q +  A+   R  
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705

Query: 270  VDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQ 329
             D    + +E+L       N         L+D + +L   + +   E+ +++ N+ A+  
Sbjct: 1706 ADLEKEELAEELASSLSGRN--------ALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757

Query: 330  AIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQS 389
             +  ++A     Q    L + R   +    A Q        +L      LR KL E E +
Sbjct: 1758 RV--RKATQQAEQLSNELATERSTAQKNESARQ--------QLERQNKELRSKLHEMEGA 1807

Query: 390  LRN-LEDIHMSLEKDIAAM 407
            +++  +    +LE  IA +
Sbjct: 1808 VKSKFKSTIAALEAKIAQL 1826



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 73/371 (19%), Positives = 139/371 (37%), Gaps = 33/371 (8%)

Query: 71   QLATETQALAQRTQQ--------DSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQ 122
            +L T+ + L Q T+Q        D  +   ER Q   +   EL+++   L  E NLL  Q
Sbjct: 836  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895

Query: 123  KQ-RLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRT 181
             Q   E   +A E+   +     +  E       +   +E  L +E +  + +Q   K+ 
Sbjct: 896  LQAETELYAEAEEMRVRLAAKKQELEE-------ILHEMEARLEEEEDRGQQLQAERKK- 947

Query: 182  IMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESAST 241
                ++Q  L+ E +   E     K++   +         +   +     +    +    
Sbjct: 948  ----MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1003

Query: 242  PETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELED 301
             E R      NL   + +      L+   + ++ +    L+ +         +  +ELE 
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE--------EKSRQELEK 1055

Query: 302  ARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAA 361
             + KL         +I D +  +A LK  +  KE  L  A  RL     + N  L +   
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR- 1114

Query: 362  QFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAH 421
               L   + +L   L + R    +AE+  R+L +   +L+ ++    +S    +Q+  A 
Sbjct: 1115 --ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST-ATQQELRAK 1171

Query: 422  RTRYPTILQLA 432
            R +  T+L+ A
Sbjct: 1172 REQEVTVLKKA 1182


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 96/451 (21%), Positives = 174/451 (38%), Gaps = 74/451 (16%)

Query: 38   KYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQD 97
            K LL+E  Q     Y +A   R +   ++ E +++  E +A  +  +    +   ER + 
Sbjct: 896  KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 955

Query: 98   THSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTD--NLQCRERREHPNL 155
                  +L+ ++E   A    L  +K   E  +   E    +  D  N   +ER+     
Sbjct: 956  AQQML-DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 1014

Query: 156  VRDHVETELLKEAELIRNIQELL-KRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDE 214
            + D + T L +E E  +N+ +L  K   M +  ++RL +E K   E++   +     ++ 
Sbjct: 1015 ISD-LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR----KLEG 1069

Query: 215  TCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCIL 274
                 H Q  ++QA       Q +    E +A   + +   AQ+   A   +R L   I 
Sbjct: 1070 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNN-ALKKIRELEGHI- 1127

Query: 275  RDTSEDLRLQCDAVNLAFGRRC---EELEDARYKLHHHLHKTLREI---TDQEHNVAALK 328
             D  EDL  +  A N A  ++    EELE  + +L   L  T  +      +E  V  LK
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1187

Query: 329  QAIKDKEAPLHVAQTRLYLRSHRPNMELCRD--------------------------AAQ 362
            +A+ D+E   H AQ +   + H   +E   +                          A +
Sbjct: 1188 KAL-DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1246

Query: 363  FRLLSEVEE--------LNMSLTALREKLLEAEQSLRNLED-IH---------------- 397
             R+L + ++        L   +  L+ K  + E++   L D +H                
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306

Query: 398  ----MSLEKDIAAMTNSLFIDRQKCMAHRTR 424
                + L KD+A++++ L  D Q+ +   TR
Sbjct: 1307 EGKAIKLAKDVASLSSQL-QDTQELLQEETR 1336



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 76/381 (19%), Positives = 152/381 (39%), Gaps = 40/381 (10%)

Query: 64   RQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQK 123
            + +HES     E +   +   +     +  +L+   S   E   +++A  AE  + LA+K
Sbjct: 1036 KNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKK 1095

Query: 124  QR-LERALDATEVPFSITTDNLQ-CRERREHPNLVRDHVETELL------KEAELIRNIQ 175
            +  L+ AL   +   +   + L+  RE   H + +++ +++E        K+   +    
Sbjct: 1096 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1155

Query: 176  ELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEV-QAHPYSTT 234
            E LK  +   +      +E +   E + +   +A  +DE    H +Q  E+ Q H  +  
Sbjct: 1156 EALKTELEDTLDSTATQQELRAKREQEVTVLKKA--LDEETRSHEAQVQEMRQKHAQAVE 1213

Query: 235  FQESASTPETRAKFTQDNLCRAQRERLA--SANLRVLVDCILRDTSEDLRLQCDAVNLAF 292
                      RAK   D   +   +  A  +  LRVL         +  +L+     L  
Sbjct: 1214 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ- 1272

Query: 293  GRRCEELEDARYKLHHHLHKTLREITDQE--------------HNVAALKQAIKDKEAPL 338
              +C + E AR +L+  +HK   E+                   +VA+L   ++D +  L
Sbjct: 1273 -SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1331

Query: 339  HV-AQTRLYLRSHRPNMELCRDAAQFRLLSEVEE----------LNMSLTALREKLLEAE 387
                + +L + +    +E  R++ Q +L  E+E           LN+ L+  ++KL +  
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1391

Query: 388  QSLRNLEDIHMSLEKDIAAMT 408
             ++  LE+     +K+I  +T
Sbjct: 1392 STVEALEEGKKRFQKEIENLT 1412



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 77/379 (20%), Positives = 139/379 (36%), Gaps = 56/379 (14%)

Query: 63   ERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKS------------------E 104
            ER R E++    ET+AL+     +      E L+ T+                      E
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1536

Query: 105  LQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNL-VRDHVETE 163
            L++   AL  +   +  Q + LE  L ATE        N+Q  + +   +L  RD    E
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596

Query: 164  LLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHS-- 221
              K  +L R + E  +  +     Q  L    K+  E D  D +E        GR  +  
Sbjct: 1597 --KRRQLQRQLHE-YETELEDERKQRALAAAAKKKLEGDLKD-LELQADSAIKGREEAIK 1652

Query: 222  --QSTEVQAHPYSTTFQE----------SASTPETRAKFTQDNLCRAQRERLASANLRVL 269
              +  + Q   +    ++          +A   E +AK  + +L + Q +  A+   R  
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1712

Query: 270  VDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQ 329
             D    + +E+L       N         L+D + +L   + +   E+ +++ N+ A+  
Sbjct: 1713 ADLEKEELAEELASSLSGRN--------ALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764

Query: 330  AIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQS 389
             +  ++A     Q    L + R   +    A Q        +L      LR KL E E +
Sbjct: 1765 RV--RKATQQAEQLSNELATERSTAQKNESARQ--------QLERQNKELRSKLHEMEGA 1814

Query: 390  LRN-LEDIHMSLEKDIAAM 407
            +++  +    +LE  IA +
Sbjct: 1815 VKSKFKSTIAALEAKIAQL 1833



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 73/371 (19%), Positives = 139/371 (37%), Gaps = 33/371 (8%)

Query: 71   QLATETQALAQRTQQ--------DSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQ 122
            +L T+ + L Q T+Q        D  +   ER Q   +   EL+++   L  E NLL  Q
Sbjct: 843  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902

Query: 123  KQ-RLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRT 181
             Q   E   +A E+   +     +  E       +   +E  L +E +  + +Q   K+ 
Sbjct: 903  LQAETELYAEAEEMRVRLAAKKQELEE-------ILHEMEARLEEEEDRGQQLQAERKK- 954

Query: 182  IMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESAST 241
                ++Q  L+ E +   E     K++   +         +   +     +    +    
Sbjct: 955  ----MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1010

Query: 242  PETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELED 301
             E R      NL   + +      L+   + ++ +    L+ +         +  +ELE 
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE--------EKSRQELEK 1062

Query: 302  ARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAA 361
             + KL         +I D +  +A LK  +  KE  L  A  RL     + N  L +   
Sbjct: 1063 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR- 1121

Query: 362  QFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAH 421
               L   + +L   L + R    +AE+  R+L +   +L+ ++    +S    +Q+  A 
Sbjct: 1122 --ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST-ATQQELRAK 1178

Query: 422  RTRYPTILQLA 432
            R +  T+L+ A
Sbjct: 1179 REQEVTVLKKA 1189


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 96/451 (21%), Positives = 174/451 (38%), Gaps = 74/451 (16%)

Query: 38   KYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQD 97
            K LL+E  Q     Y +A   R +   ++ E +++  E +A  +  +    +   ER + 
Sbjct: 896  KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 955

Query: 98   THSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTD--NLQCRERREHPNL 155
                  +L+ ++E   A    L  +K   E  +   E    +  D  N   +ER+     
Sbjct: 956  AQQML-DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 1014

Query: 156  VRDHVETELLKEAELIRNIQELL-KRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDE 214
            + D + T L +E E  +N+ +L  K   M +  ++RL +E K   E++   +     ++ 
Sbjct: 1015 ISD-LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR----KLEG 1069

Query: 215  TCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCIL 274
                 H Q  ++QA       Q +    E +A   + +   AQ+   A   +R L   I 
Sbjct: 1070 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNN-ALKKIRELEGHI- 1127

Query: 275  RDTSEDLRLQCDAVNLAFGRRC---EELEDARYKLHHHLHKTLREI---TDQEHNVAALK 328
             D  EDL  +  A N A  ++    EELE  + +L   L  T  +      +E  V  LK
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1187

Query: 329  QAIKDKEAPLHVAQTRLYLRSHRPNMELCRD--------------------------AAQ 362
            +A+ D+E   H AQ +   + H   +E   +                          A +
Sbjct: 1188 KAL-DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1246

Query: 363  FRLLSEVEE--------LNMSLTALREKLLEAEQSLRNLED-IH---------------- 397
             R+L + ++        L   +  L+ K  + E++   L D +H                
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306

Query: 398  ----MSLEKDIAAMTNSLFIDRQKCMAHRTR 424
                + L KD+A++++ L  D Q+ +   TR
Sbjct: 1307 EGKAIKLAKDVASLSSQL-QDTQELLQEETR 1336



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 76/381 (19%), Positives = 152/381 (39%), Gaps = 40/381 (10%)

Query: 64   RQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQK 123
            + +HES     E +   +   +     +  +L+   S   E   +++A  AE  + LA+K
Sbjct: 1036 KNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKK 1095

Query: 124  QR-LERALDATEVPFSITTDNLQ-CRERREHPNLVRDHVETELL------KEAELIRNIQ 175
            +  L+ AL   +   +   + L+  RE   H + +++ +++E        K+   +    
Sbjct: 1096 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1155

Query: 176  ELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEV-QAHPYSTT 234
            E LK  +   +      +E +   E + +   +A  +DE    H +Q  E+ Q H  +  
Sbjct: 1156 EALKTELEDTLDSTATQQELRAKREQEVTVLKKA--LDEETRSHEAQVQEMRQKHAQAVE 1213

Query: 235  FQESASTPETRAKFTQDNLCRAQRERLA--SANLRVLVDCILRDTSEDLRLQCDAVNLAF 292
                      RAK   D   +   +  A  +  LRVL         +  +L+     L  
Sbjct: 1214 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ- 1272

Query: 293  GRRCEELEDARYKLHHHLHKTLREITDQE--------------HNVAALKQAIKDKEAPL 338
              +C + E AR +L+  +HK   E+                   +VA+L   ++D +  L
Sbjct: 1273 -SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1331

Query: 339  HV-AQTRLYLRSHRPNMELCRDAAQFRLLSEVEE----------LNMSLTALREKLLEAE 387
                + +L + +    +E  R++ Q +L  E+E           LN+ L+  ++KL +  
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1391

Query: 388  QSLRNLEDIHMSLEKDIAAMT 408
             ++  LE+     +K+I  +T
Sbjct: 1392 STVEALEEGKKRFQKEIENLT 1412



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 77/379 (20%), Positives = 139/379 (36%), Gaps = 56/379 (14%)

Query: 63   ERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKS------------------E 104
            ER R E++    ET+AL+     +      E L+ T+                      E
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1536

Query: 105  LQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNL-VRDHVETE 163
            L++   AL  +   +  Q + LE  L ATE        N+Q  + +   +L  RD    E
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596

Query: 164  LLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHS-- 221
              K  +L R + E  +  +     Q  L    K+  E D  D +E        GR  +  
Sbjct: 1597 --KRRQLQRQLHE-YETELEDERKQRALAAAAKKKLEGDLKD-LELQADSAIKGREEAIK 1652

Query: 222  --QSTEVQAHPYSTTFQE----------SASTPETRAKFTQDNLCRAQRERLASANLRVL 269
              +  + Q   +    ++          +A   E +AK  + +L + Q +  A+   R  
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1712

Query: 270  VDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQ 329
             D    + +E+L       N         L+D + +L   + +   E+ +++ N+ A+  
Sbjct: 1713 ADLEKEELAEELASSLSGRN--------ALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1764

Query: 330  AIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQS 389
             +  ++A     Q    L + R   +    A Q        +L      LR KL E E +
Sbjct: 1765 RV--RKATQQAEQLSNELATERSTAQKNESARQ--------QLERQNKELRSKLHEMEGA 1814

Query: 390  LRN-LEDIHMSLEKDIAAM 407
            +++  +    +LE  IA +
Sbjct: 1815 VKSKFKSTIAALEAKIAQL 1833



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 73/371 (19%), Positives = 139/371 (37%), Gaps = 33/371 (8%)

Query: 71   QLATETQALAQRTQQ--------DSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQ 122
            +L T+ + L Q T+Q        D  +   ER Q   +   EL+++   L  E NLL  Q
Sbjct: 843  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 902

Query: 123  KQ-RLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRT 181
             Q   E   +A E+   +     +  E       +   +E  L +E +  + +Q   K+ 
Sbjct: 903  LQAETELYAEAEEMRVRLAAKKQELEE-------ILHEMEARLEEEEDRGQQLQAERKK- 954

Query: 182  IMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESAST 241
                ++Q  L+ E +   E     K++   +         +   +     +    +    
Sbjct: 955  ----MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1010

Query: 242  PETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELED 301
             E R      NL   + +      L+   + ++ +    L+ +         +  +ELE 
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE--------EKSRQELEK 1062

Query: 302  ARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAA 361
             + KL         +I D +  +A LK  +  KE  L  A  RL     + N  L +   
Sbjct: 1063 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR- 1121

Query: 362  QFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAH 421
               L   + +L   L + R    +AE+  R+L +   +L+ ++    +S    +Q+  A 
Sbjct: 1122 --ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST-ATQQELRAK 1178

Query: 422  RTRYPTILQLA 432
            R +  T+L+ A
Sbjct: 1179 REQEVTVLKKA 1189


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 96/451 (21%), Positives = 174/451 (38%), Gaps = 74/451 (16%)

Query: 38   KYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQD 97
            K LL+E  Q     Y +A   R +   ++ E +++  E +A  +  +    +   ER + 
Sbjct: 889  KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 948

Query: 98   THSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTD--NLQCRERREHPNL 155
                  +L+ ++E   A    L  +K   E  +   E    +  D  N   +ER+     
Sbjct: 949  AQQML-DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 1007

Query: 156  VRDHVETELLKEAELIRNIQELL-KRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDE 214
            + D + T L +E E  +N+ +L  K   M +  ++RL +E K   E++   +     ++ 
Sbjct: 1008 ISD-LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR----KLEG 1062

Query: 215  TCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCIL 274
                 H Q  ++QA       Q +    E +A   + +   AQ+   A   +R L   I 
Sbjct: 1063 DASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNN-ALKKIRELEGHI- 1120

Query: 275  RDTSEDLRLQCDAVNLAFGRRC---EELEDARYKLHHHLHKTLREI---TDQEHNVAALK 328
             D  EDL  +  A N A  ++    EELE  + +L   L  T  +      +E  V  LK
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1180

Query: 329  QAIKDKEAPLHVAQTRLYLRSHRPNMELCRD--------------------------AAQ 362
            +A+ D+E   H AQ +   + H   +E   +                          A +
Sbjct: 1181 KAL-DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1239

Query: 363  FRLLSEVEE--------LNMSLTALREKLLEAEQSLRNLED-IH---------------- 397
             R+L + ++        L   +  L+ K  + E++   L D +H                
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299

Query: 398  ----MSLEKDIAAMTNSLFIDRQKCMAHRTR 424
                + L KD+A++++ L  D Q+ +   TR
Sbjct: 1300 EGKAIKLAKDVASLSSQL-QDTQELLQEETR 1329



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 76/381 (19%), Positives = 152/381 (39%), Gaps = 40/381 (10%)

Query: 64   RQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQK 123
            + +HES     E +   +   +     +  +L+   S   E   +++A  AE  + LA+K
Sbjct: 1029 KNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKK 1088

Query: 124  QR-LERALDATEVPFSITTDNLQ-CRERREHPNLVRDHVETELL------KEAELIRNIQ 175
            +  L+ AL   +   +   + L+  RE   H + +++ +++E        K+   +    
Sbjct: 1089 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148

Query: 176  ELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEV-QAHPYSTT 234
            E LK  +   +      +E +   E + +   +A  +DE    H +Q  E+ Q H  +  
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKREQEVTVLKKA--LDEETRSHEAQVQEMRQKHAQAVE 1206

Query: 235  FQESASTPETRAKFTQDNLCRAQRERLA--SANLRVLVDCILRDTSEDLRLQCDAVNLAF 292
                      RAK   D   +   +  A  +  LRVL         +  +L+     L  
Sbjct: 1207 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ- 1265

Query: 293  GRRCEELEDARYKLHHHLHKTLREITDQE--------------HNVAALKQAIKDKEAPL 338
              +C + E AR +L+  +HK   E+                   +VA+L   ++D +  L
Sbjct: 1266 -SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324

Query: 339  HV-AQTRLYLRSHRPNMELCRDAAQFRLLSEVEE----------LNMSLTALREKLLEAE 387
                + +L + +    +E  R++ Q +L  E+E           LN+ L+  ++KL +  
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 1384

Query: 388  QSLRNLEDIHMSLEKDIAAMT 408
             ++  LE+     +K+I  +T
Sbjct: 1385 STVEALEEGKKRFQKEIENLT 1405



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 77/379 (20%), Positives = 139/379 (36%), Gaps = 56/379 (14%)

Query: 63   ERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKS------------------E 104
            ER R E++    ET+AL+     +      E L+ T+                      E
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529

Query: 105  LQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNL-VRDHVETE 163
            L++   AL  +   +  Q + LE  L ATE        N+Q  + +   +L  RD    E
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589

Query: 164  LLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHS-- 221
              K  +L R + E  +  +     Q  L    K+  E D  D +E        GR  +  
Sbjct: 1590 --KRRQLQRQLHE-YETELEDERKQRALAAAAKKKLEGDLKD-LELQADSAIKGREEAIK 1645

Query: 222  --QSTEVQAHPYSTTFQE----------SASTPETRAKFTQDNLCRAQRERLASANLRVL 269
              +  + Q   +    ++          +A   E +AK  + +L + Q +  A+   R  
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705

Query: 270  VDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQ 329
             D    + +E+L       N         L+D + +L   + +   E+ +++ N+ A+  
Sbjct: 1706 ADLEKEELAEELASSLSGRN--------ALQDEKRRLEARIAQLEEELEEEQGNMEAMSD 1757

Query: 330  AIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQS 389
             +  ++A     Q    L + R   +    A Q        +L      LR KL E E +
Sbjct: 1758 RV--RKATQQAEQLSNELATERSTAQKNESARQ--------QLERQNKELRSKLHEMEGA 1807

Query: 390  LRN-LEDIHMSLEKDIAAM 407
            +++  +    +LE  IA +
Sbjct: 1808 VKSKFKSTIAALEAKIAQL 1826



 Score = 36.2 bits (82), Expect = 0.060
 Identities = 73/371 (19%), Positives = 139/371 (37%), Gaps = 33/371 (8%)

Query: 71   QLATETQALAQRTQQ--------DSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQ 122
            +L T+ + L Q T+Q        D  +   ER Q   +   EL+++   L  E NLL  Q
Sbjct: 836  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895

Query: 123  KQ-RLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRT 181
             Q   E   +A E+   +     +  E       +   +E  L +E +  + +Q   K+ 
Sbjct: 896  LQAETELYAEAEEMRVRLAAKKQELEE-------ILHEMEARLEEEEDRGQQLQAERKK- 947

Query: 182  IMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESAST 241
                ++Q  L+ E +   E     K++   +         +   +     +    +    
Sbjct: 948  ----MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1003

Query: 242  PETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELED 301
             E R      NL   + +      L+   + ++ +    L+ +         +  +ELE 
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE--------EKSRQELEK 1055

Query: 302  ARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAA 361
             + KL         +I D +  +A LK  +  KE  L  A  RL     + N  L +   
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR- 1114

Query: 362  QFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAH 421
               L   + +L   L + R    +AE+  R+L +   +L+ ++    +S    +Q+  A 
Sbjct: 1115 --ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST-ATQQELRAK 1171

Query: 422  RTRYPTILQLA 432
            R +  T+L+ A
Sbjct: 1172 REQEVTVLKKA 1182


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 79/374 (21%), Positives = 134/374 (35%), Gaps = 36/374 (9%)

Query: 54  QAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALA 113
           Q   D+     Q HE  Q   +    A          +   LQ       EL++E E L 
Sbjct: 571 QRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQ 630

Query: 114 AETNLLLAQKQRLERALDATEVPFSITTDNLQ--CRERREHPNLVRDHVETELL--KEAE 169
           A    L  Q+ RLE   +          D +Q   R RRE   L R H + E L  K + 
Sbjct: 631 AAQEELRRQRDRLEEEQE----------DAVQDGARVRRE---LERSHRQLEQLEGKRSV 677

Query: 170 LIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQ-- 227
           L + + E+ +      + +  L  E  E  E     +     ++ +  +  ++   +Q  
Sbjct: 678 LAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDS 737

Query: 228 ----AHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRL 283
               +    +  Q+        A+  ++      R+R A     V  +   ++  E+LRL
Sbjct: 738 LSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVARE--EQERLEELRL 795

Query: 284 QCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQT 343
           + +             E A+  L   L     E +  +  +A L + +  +E  L  A+ 
Sbjct: 796 EQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQAR- 854

Query: 344 RLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKD 403
               R  +  +E    AA+     E E L      L  +L+ AE+  R L +    L  +
Sbjct: 855 ----REAQRQVEALERAAR-----EKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLE 905

Query: 404 IAAMTNSLF-IDRQ 416
             A+  SLF + RQ
Sbjct: 906 KEALEGSLFEVQRQ 919



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 81/433 (18%), Positives = 157/433 (36%), Gaps = 34/433 (7%)

Query: 7    PCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQSERQR 66
            P  L C       + G  TS           +  L E+ Q   +   +    R Q+    
Sbjct: 1477 PSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERDELRTQTSALN 1536

Query: 67   HESQQLATETQALAQRTQQ---------DSTRTVGERLQDTHSWKSELQREMEALAAETN 117
             +  ++  E  +   R +Q         ++ R+V  RL    +  +  +  +     E  
Sbjct: 1537 RQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERR 1596

Query: 118  LLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQ-E 176
              L Q   LER+L ATE     + + +  + +     L  D    + + +A   R ++ E
Sbjct: 1597 ATLDQVATLERSLQATESELRASQEKIS-KMKANETKLEGDKRRLKEVLDASESRTVKLE 1655

Query: 177  LLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQ 236
            L +R++   + + RL    +E       D++++        +     +EV+A     T +
Sbjct: 1656 LQRRSLEGELQRSRLGLSDREAQAQALQDRVDSL-------QRQVADSEVKAGTLQLTVE 1708

Query: 237  --ESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGR 294
                A      ++    +  R   E LA ++  +       +++ D  L       A   
Sbjct: 1709 RLNGALAKVEESEGALRDKVRGLTEALAQSSASL-------NSTRDKNLHLQKALTACEH 1761

Query: 295  RCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKD-----KEAPLHVAQTRLYLRS 349
              + L++        L +  ++ +     V  L+  + D      EA   + Q R  LR 
Sbjct: 1762 DRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQ 1821

Query: 350  HRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTN 409
             +       +  Q +L  E   L   L +L+  L + E   R +E   + LEKD  A+  
Sbjct: 1822 RQEGEAAALNTVQ-KLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRR 1880

Query: 410  SL-FIDRQKCMAH 421
            +L  ++R+K  +H
Sbjct: 1881 TLDKVEREKLRSH 1893


>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
          Length = 775

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 80/348 (22%), Positives = 138/348 (39%), Gaps = 53/348 (15%)

Query: 61  QSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHS-----WKSELQREMEALAAE 115
           Q+++   E ++L +E QA+     Q   R   + LQ+  +     ++++LQ+EM   A  
Sbjct: 291 QTKQLTREVEELKSELQAIRDEKNQPDPRL--QELQEEAARLKSHFQAQLQQEMRKTALA 348

Query: 116 TNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQ 175
            + L  Q Q  E+ + A E   S  ++ L   E+ +     +D +  + LKE  L  +++
Sbjct: 349 EDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQ----KDQLAIQKLKERILQLDLE 404

Query: 176 ELLKRTIMQAVSQIRLNREHKETCEMDWS---DKMEAYNIDETCGRHHSQST-------E 225
               +T+  A S       H E   +D +   DKME            SQ T       +
Sbjct: 405 N---KTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCD 461

Query: 226 VQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSE-DLRLQ 284
           ++  P S    E+A   +  A + Q  L +  +E      +R  V    ++T + +L  +
Sbjct: 462 LEIMPSS----EAADGEKATALYYQQEL-KQLKEEFERYKMRAQVVLKSKNTKDGNLGKE 516

Query: 285 CDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTR 344
            +A         E+    R       H+  +E  D +  +A L+Q               
Sbjct: 517 LEAAQEQLAELKEKYISLRLSCEELEHQHQQEADDWKQELARLQQL-------------- 562

Query: 345 LYLRSHRPNMELCRDAAQFRLLSEVEEL----NMSLTALREKLLEAEQ 388
                HR  +E C+   + R L   EEL    + +L  L EK LE EQ
Sbjct: 563 -----HRQELERCQLDFRDRTLKLEEELHKQRDRALAVLTEKDLELEQ 605



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 78/370 (21%), Positives = 146/370 (39%), Gaps = 45/370 (12%)

Query: 56  FADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAE 115
           FA  +  +R      QLAT T +LA  TQ+ S R     L D    K +L+        E
Sbjct: 149 FAGGEVDKRLHQLKTQLATLTSSLATVTQEKS-RMEASYLADKKKMKQDLEDASNKAEEE 207

Query: 116 TNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQ 175
              L  + + L+  +  T+    IT  + + +E+ +H  ++R+    +LL+E    R   
Sbjct: 208 RARLEGELKGLQEQIAETKARL-ITQQHDRAQEQSDHALMLRE--LQKLLQEERTQRQDL 264

Query: 176 ELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTF 235
           EL      +A++      E  E  E+    K     ++E         +E+QA       
Sbjct: 265 ELRLEETREALAGRAYAAEQMEGFEL--QTKQLTREVEEL-------KSELQA------I 309

Query: 236 QESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRR 295
           ++  + P+ R +  Q+   R +    A     +    +  D    LR Q           
Sbjct: 310 RDEKNQPDPRLQELQEEAARLKSHFQAQLQQEMRKTALAED---QLRQQ----------- 355

Query: 296 CEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNME 355
             ++E+ R      L   + E+++        KQ  KD+ A   + +  L L      + 
Sbjct: 356 -SQVEEQRVAA---LENQISEVSELLGTYEKAKQ--KDQLAIQKLKERILQLDLENKTLA 409

Query: 356 LCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLR---NLEDIHMSLEK--DIAAMTNS 410
           L   +++  L S  EE ++ +  L++K+ + ++ L+       + + +EK  D+  M +S
Sbjct: 410 LAA-SSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSS 468

Query: 411 LFIDRQKCMA 420
              D +K  A
Sbjct: 469 EAADGEKATA 478


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 76/341 (22%), Positives = 135/341 (39%), Gaps = 39/341 (11%)

Query: 63  ERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQ 122
           E QRH S         +A +T  +S  T  E+ +       ELQ  ++ L+ +   + A+
Sbjct: 232 ELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQ------ELQALIQQLSIDLQKVTAE 285

Query: 123 KQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELI-RNIQELLKRT 181
            Q  E  +   +       + +   E+R   NL  +    ELLKE  L  +N+++  ++ 
Sbjct: 286 TQEKEDVITHLQ-------EKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQL 338

Query: 182 IMQAVSQIR-LNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESAS 240
           +    SQ + +N       E++ + +     + ++ G   +Q T++Q    +   QES+ 
Sbjct: 339 LAARSSQAKAINTLETRVRELEQTLQASEEQLQQSKGIVAAQETQIQ--ELAAANQESSH 396

Query: 241 TPETRAKFTQDNLCRAQRERLASANLRVLVDCILRD--TSEDLRLQCDAVNLAFGRRCEE 298
             +      Q  L   +R +   A +  L      D  T+E    Q +  N A      E
Sbjct: 397 VQQQALALEQQFL---ERTQALEAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNE 453

Query: 299 LEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCR 358
            E +       L K   E + +E    A+ QA+++             +R  R   E  +
Sbjct: 454 YERSLQNHQFELKKLKEEWSQREIVSVAMAQALEE-------------VRKQRE--EFQQ 498

Query: 359 DAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMS 399
            AA   L + ++E   +L    E LL+ EQ +  LE  H S
Sbjct: 499 QAA--NLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNS 537


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 82/368 (22%), Positives = 141/368 (38%), Gaps = 45/368 (12%)

Query: 64   RQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQK 123
            R  HE    A ET     +  Q+    + +++  +     EL++  +AL  E + + A  
Sbjct: 1534 RHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAAL 1593

Query: 124  QRLERALDATEV----------PFSITTDNLQCRERREHPNLVRDHVETELLKEAEL--- 170
            +  E AL+  E                 D     +  E  NL R+H       +A L   
Sbjct: 1594 EEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAE 1653

Query: 171  --IRNIQELLKRTIMQAVSQIRLNREH--KETCEMDWSDK-MEAYNIDETCGRHHSQSTE 225
               RN    LK+ +   ++ + L   H  ++  E   + + M+A   +E  GR   Q   
Sbjct: 1654 TRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLA 1713

Query: 226  VQAHPYSTTFQESAS-----TPETRAKFTQDNLCR--AQRERL-ASANLRVLVDCILRDT 277
             + H  +   +  AS       E RA   Q    R  A++E L A+  L +L        
Sbjct: 1714 AELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLL 1773

Query: 278  SEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAP 337
            ++  +L+ D   L+      E+E+A  +      K  + ITD       LK   K+++  
Sbjct: 1774 NQKKKLEADLAQLS-----GEVEEAAQERREAEEKAKKAITDAAMMAEELK---KEQDTS 1825

Query: 338  LHVAQTRLYL----RSHRPNMELCRDAA-------QFRLLSEVEELNMSLTALREKLLEA 386
             H+ + +  L    R  +  +E    AA         +L ++V EL   L A ++K  EA
Sbjct: 1826 AHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEA 1885

Query: 387  EQSLRNLE 394
             + +R  E
Sbjct: 1886 LKGVRKHE 1893



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 69/353 (19%), Positives = 126/353 (35%), Gaps = 68/353 (19%)

Query: 57   ADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAET 116
            A+  +  R+  E+      T A  +R Q +    +GE++      + +L++E   L  E 
Sbjct: 1218 AELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEV 1277

Query: 117  NLLLAQKQRLERALDATEVPFSITTDNL--------QCRERREHPNLVRDHVETE----- 163
            + L A  + L RA  + E       D L        + + +    +  R  ++TE     
Sbjct: 1278 DDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELS 1337

Query: 164  -LLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNID-ETCGRHHS 221
             LL+E E + +     K    Q++ ++R   E +   +   +  ++A   D +     H 
Sbjct: 1338 RLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHE 1397

Query: 222  QSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDL 281
            +  E QA       + +A   + R+K+  D +                            
Sbjct: 1398 EEAEAQAELQRLLSKANAEVAQWRSKYEADAI---------------------------- 1429

Query: 282  RLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVA 341
                        +R EELE+A+ KL   L +    +           +A   K + L  A
Sbjct: 1430 ------------QRTEELEEAKKKLALRLQEAEEGV-----------EAANAKCSSLEKA 1466

Query: 342  QTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLE 394
            + RL   S    +EL R  +    L + +       AL E+  + E+  R LE
Sbjct: 1467 KLRLQTESEDVTLELERATSAAAALDKKQ--RHLERALEERRRQEEEMQRELE 1517



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 78/375 (20%), Positives = 154/375 (41%), Gaps = 48/375 (12%)

Query: 54   QAFADRDQSERQRHES-QQLATETQALAQRTQQDST--RTVGERLQDTHSWKSELQREME 110
            ++ AD  Q ++Q  E  ++  +E   L+ R + +      + +++++  +   EL+ E+E
Sbjct: 1113 ESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELE 1172

Query: 111  ALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAEL 170
            A  A    +  +KQR E A +  E+   +         +RE              +EAEL
Sbjct: 1173 AERAARARV--EKQRAEAARELEELSERLEEAGGASAGQREGCRK----------REAEL 1220

Query: 171  IRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHP 230
             R  +EL +  +    +   L R+  E    +  +++++        +   Q  E +   
Sbjct: 1221 GRLRRELEEAALRHEATVAALRRKQAEGAA-ELGEQVDSL-------QRVRQKLEKEKSE 1272

Query: 231  YSTTFQESASTPET--RAKFTQDNLCRAQRERLASANLRV--LVDCILRDTSEDLRLQCD 286
                  + A+  ET  RAK + + LCR   ++L+ A ++V  L   +   +++  RLQ +
Sbjct: 1273 LRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTE 1332

Query: 287  AVNLAFGRRCEELE--------------DARYKLHHHLHKTLREITDQEHNVAALK---Q 329
            +  L+  R  EE E               +  +L   L +  +  +   H V AL+    
Sbjct: 1333 SGELS--RLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCD 1390

Query: 330  AIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFR--LLSEVEELNMSLTALREKLLEAE 387
             ++++      AQ  L     + N E+ +  +++    +   EEL  +   L  +L EAE
Sbjct: 1391 LLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAE 1450

Query: 388  QSLRNLEDIHMSLEK 402
            + +        SLEK
Sbjct: 1451 EGVEAANAKCSSLEK 1465



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 82/374 (21%), Positives = 145/374 (38%), Gaps = 37/374 (9%)

Query: 73   ATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRL----ER 128
            AT   A   + Q+   R + ER +     + E+QRE+EA   E+  L  +  RL    E 
Sbjct: 1484 ATSAAAALDKKQRHLERALEERRRQ----EEEMQRELEAAQRESRGLGTELFRLRHGHEE 1539

Query: 129  ALDATEVPFSITTDNLQCRERREHPNLVRDHVET--ELLKEAELIRNIQELLKRTIMQAV 186
            AL+A E      T   + +  +E  + + D V    + ++E E  +   E  K  I  A+
Sbjct: 1540 ALEALE------TLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAAL 1593

Query: 187  SQIR--LNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQA-HPYSTTFQESASTPE 243
             +    L  E  +T  +          +D        +   ++  H  +    +++   E
Sbjct: 1594 EEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAE 1653

Query: 244  TRAKFTQDNLCRAQRERLASAN-LRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEEL--E 300
            TRA+   +   R +++     N L + +    R  +E       A  L   +  EE    
Sbjct: 1654 TRAR---NEALRLKKKMEGDLNDLELQLGHATRQATEAQA----ATRLMQAQLKEEQAGR 1706

Query: 301  DARYKLHHHLHKTLREITDQEHNVAA----LKQAIKDKEAPLHVAQTRLYLRSHRPNMEL 356
            D   +L   LH+  + +  +   +AA    L+ A++  E    +A+  L   + R N+  
Sbjct: 1707 DEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLH 1766

Query: 357  CRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQ 416
             ++     LL++ ++L   L  L  ++ EA Q  R  E+       D A M   L    Q
Sbjct: 1767 SQNTG---LLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEEL-KKEQ 1822

Query: 417  KCMAHRTRYPTILQ 430
               AH  R    L+
Sbjct: 1823 DTSAHLERMKKTLE 1836


>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
          Length = 1194

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 78/372 (20%), Positives = 138/372 (37%), Gaps = 51/372 (13%)

Query: 72  LATETQALAQ--RTQQDSTRTVGERLQDTHSWKSELQREM------EALAAETNLLLAQK 123
           + TE + L +  R  QD   T   RL++    K  LQR++      E  A    L L ++
Sbjct: 35  MLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCRE 94

Query: 124 QRLERALDATEVPFS-----ITTDNLQCRERREHPNLVRDHV------------ETELLK 166
           Q LER  +  E+        +  ++L+C   R   +L    V            E E+LK
Sbjct: 95  QLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLK 154

Query: 167 EAELI----RNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQ 222
             + +    + + E ++  +  A+ ++ +  E  E          E  N+ E   R  S 
Sbjct: 155 ALKSLFEHHKALDEKVRERLRMALERVAVLEEELEL------SNQETLNLREQLSRRRSG 208

Query: 223 STEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLR 282
             E        T            + T +     +R+R     LR  +  + R  S+ L 
Sbjct: 209 LEEPGKDGDGQTLANGLGPGGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQ-LE 267

Query: 283 LQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQ---AIKDKEAPLH 339
            +    +   G+     E+A  KL   L + L +  D E  +  L++   + + +   LH
Sbjct: 268 EELGTAHRELGKA----EEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLH 323

Query: 340 VAQTRLYLRSHRPNMELCRDAAQFRLLSE-VEELNMSLTALREKLLEAEQSLRNLEDIHM 398
            A  +L         EL    + +R   E   +L   L   ++KL +  Q    L +I  
Sbjct: 324 DANDKL-------ENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEA 376

Query: 399 SLEKDIAAMTNS 410
            L + +AA+  +
Sbjct: 377 QLAQRVAALNKA 388


>gi|56550043 sarcolemma associated protein [Homo sapiens]
          Length = 811

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 71/383 (18%), Positives = 156/383 (40%), Gaps = 44/383 (11%)

Query: 59  RDQSERQRHESQQLATETQALAQRTQQDSTRT-VGERLQDTHSWKSELQREMEALAAETN 117
           ++ +ER + E ++LA +        +  S +  V E  Q+    K   Q E + L  + +
Sbjct: 290 KEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKG--QAEKKELQHKID 347

Query: 118 LLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQEL 177
            +  ++Q L+  ++A +     T + L           +++H+ ++   +   I    E 
Sbjct: 348 EMEEKEQELQAKIEALQADNDFTNERLTA---------LQEHLLSKSGGDCTFIHQFIEC 398

Query: 178 LKRTIMQ-----AVSQIRLNREHKETC-EMDWSDKMEAYNIDETCGRHHSQSTEVQAHPY 231
            K+ I++     AV + +L++E++    E D+SD      +  +  +    +T+ Q    
Sbjct: 399 QKKLIVEGHLTKAVEETKLSKENQTRAKESDFSD-----TLSPSKEKSSDDTTDAQMD-- 451

Query: 232 STTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCIL--RDTSEDLRLQCDAVN 289
               ++  + P  +    +D+L  AQ E  A   ++ L   ++  ++ +   + +C  + 
Sbjct: 452 ----EQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQ 507

Query: 290 LAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKD--KEAPLHVAQTRLYL 347
                    LE+ R    + + ++ ++I   +  +  L    ++  +E    +  TR  L
Sbjct: 508 AL-------LEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDEL 560

Query: 348 RSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAM 407
            S R  + L   AA         E +  + +L+E+L +    L          EK+I ++
Sbjct: 561 LSARDEILLLHQAAA----KVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSL 616

Query: 408 TNSLFIDRQKCMAHRTRYPTILQ 430
            NS  +  Q+C   +    T LQ
Sbjct: 617 QNSFQLRCQQCEDQQREEATRLQ 639


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 87/449 (19%), Positives = 173/449 (38%), Gaps = 73/449 (16%)

Query: 46   QNCYARYHQAFADRDQSERQRHESQQ----LATETQALAQRTQQ---------------- 85
            Q  Y +     A++ ++E+Q  E++Q    +  + +  A+  QQ                
Sbjct: 1644 QELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEV 1703

Query: 86   ----DSTRTVGERLQDTH-SWKSELQR---EMEALAAETNLLLAQKQRLERALDAT--EV 135
                D+ +   E L  ++ S K EL+R   E E L+ +   L+++K  L   +     ++
Sbjct: 1704 HPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQI 1763

Query: 136  PFSITTD-NLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNRE 194
              +++   NL+  E+ ++   V +     +  E E   ++    + T  ++V   +    
Sbjct: 1764 EGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAK---S 1820

Query: 195  HKETCEMDWSDKMEAYN----IDETCGRHHSQSTEVQAHP-YSTTFQESA-------STP 242
                   D+S   E  N    ID+   R      E Q +  +S T +          ST 
Sbjct: 1821 ANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTK 1880

Query: 243  ETRAKFTQDNLCRA-------QRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRR 295
            +   K  Q+ + +        Q E      L+   +    D  E L  Q   +N + G  
Sbjct: 1881 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNY 1940

Query: 296  CEELEDARYKLH------HHLHKTLREITDQEHNVAALKQAI-----KDKEAPLHVAQTR 344
            C+++ DA+ K         +L K + E+ +++  +   K  +     K+    +  AQ  
Sbjct: 1941 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKE 2000

Query: 345  LYLRSHRPNM-ELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKD 403
               +SH   + EL ++  Q     EV++L       +EK+   E++++ LE +    +KD
Sbjct: 2001 PGNKSHAKELQELLKEKQQ-----EVKQLQKDCIRYQEKISALERTVKALEFVQTESQKD 2055

Query: 404  IAAMTNSL---FIDRQKCMAHRTRYPTIL 429
            +     +L      R+K  A    +  +L
Sbjct: 2056 LEITKENLAQAVEHRKKAQAELASFKVLL 2084



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 83/352 (23%), Positives = 145/352 (41%), Gaps = 47/352 (13%)

Query: 68   ESQQLATETQALAQRTQQDSTRTVGE--RLQDTHSWKSELQREMEALAAETNLLLAQKQR 125
            E Q+L  E Q   ++ Q+D  R   +   L+ T      +Q E +     T   LAQ   
Sbjct: 2009 ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVE 2068

Query: 126  LERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEA--ELIRNIQELLKRTIM 183
              +   A    F +  D+ Q    R   + ++   E +  KE+    ++   E L+R + 
Sbjct: 2069 HRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLE 2128

Query: 184  QAVSQIRLNREHKETCEMDWSDKMEAYNIDETCG-------RHHSQSTEVQAHPYSTTFQ 236
            QA  + +  +E K   E   + + E  +++ET G       +   +  ++Q +  ST  Q
Sbjct: 2129 QA--EEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQ 2186

Query: 237  ESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRC 296
             +A T    +   QD+  R   E  A    R   D I +   E++RL+ D         C
Sbjct: 2187 LAAFTKSMSS--LQDDRDRVIDE--AKKWERKFSDAI-QSKEEEIRLKED--------NC 2233

Query: 297  EELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMEL 356
              L+D   ++  H+ +    I+  EH+    KQ  + K      AQT + L+      ++
Sbjct: 2234 SVLKDQLRQMSIHMEELKINISRLEHD----KQIWESK------AQTEVQLQQ-----KV 2278

Query: 357  CR--DAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLE----DIHMSLEK 402
            C         LLS++EE      + + +L + E  L++L+    D+  SLEK
Sbjct: 2279 CDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEK 2330



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 69/355 (19%), Positives = 138/355 (38%), Gaps = 74/355 (20%)

Query: 54   QAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALA 113
            QA   R +++ +    + L  +TQ+ A R   D+ +   E   +  S KS+++++ E L 
Sbjct: 2065 QAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLE 2124

Query: 114  AETNLL----LAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAE 169
                      L +K+ ++  LDA              R  + H       ++  L K+ +
Sbjct: 2125 RRLEQAEEKHLKEKKNMQEKLDA-------------LRREKVHLEETIGEIQVTLNKKDK 2171

Query: 170  LIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAH 229
             ++ +QE L  T+ Q  +  +       +   D  D++    IDE             A 
Sbjct: 2172 EVQQLQENLDSTVTQLAAFTK-----SMSSLQDDRDRV----IDE-------------AK 2209

Query: 230  PYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVN 289
             +   F ++  + E   +  +DN C   +++L   ++ +          E+L+     +N
Sbjct: 2210 KWERKFSDAIQSKEEEIRLKEDN-CSVLKDQLRQMSIHM----------EELK-----IN 2253

Query: 290  LAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRS 349
            ++     +++ +++ +    L + + +    E+     K+ +   E   H     LY   
Sbjct: 2254 ISRLEHDKQIWESKAQTEVQLQQKVCDTLQGEN-----KELLSQLEETRH-----LY--- 2300

Query: 350  HRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDI 404
            H    EL       +L SE++ L   LT L   L + ++   NLE I    E DI
Sbjct: 2301 HSSQNELA------KLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADI 2349



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 72/363 (19%), Positives = 147/363 (40%), Gaps = 33/363 (9%)

Query: 72  LATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLERALD 131
           L TE Q+  Q ++ D + T  E   +    K +LQ E E L +     L Q Q  + A  
Sbjct: 122 LPTEPQSEEQLSKHDKSST--EEEMEIEKIKHKLQ-EKEELISTLQAQLTQAQAEQPAQS 178

Query: 132 ATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRL 191
           +TE+   +     Q +E+ E  + ++  +     ++A      Q++++    +  +Q+RL
Sbjct: 179 STEMEEFVMMKQ-QLQEKEEFISTLQAQLSQTQAEQAA-----QQVVREKDARFETQVRL 232

Query: 192 NREH--KETCEMDWSDKMEA-YNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETRAKF 248
           + +   +   + D   +M+    + +     H +S   +A       Q+  +  E R + 
Sbjct: 233 HEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDL-LQQELTAAEQRNQI 291

Query: 249 TQDNLCRAQRERLASANLRVLVDCILRDTS---EDLRLQCDAVNLAFGRRCEELEDARYK 305
               L + + E      LR  V+    ++    E + L+     L+F    EE+      
Sbjct: 292 LSQQLQQMEAEH---NTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEM------ 342

Query: 306 LHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRL 365
             HHL +   +    +  + +   A++ K       +T   L   +   EL   +A   L
Sbjct: 343 --HHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQEL--QSACDAL 398

Query: 366 LSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAHRTRY 425
             +  +L   L    E+ +++ Q+++ LED      K+I+   N L + + +  A +T +
Sbjct: 399 KDQNSKL---LQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHE-TASQTSF 454

Query: 426 PTI 428
           P +
Sbjct: 455 PDV 457



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 24/126 (19%), Positives = 52/126 (41%), Gaps = 2/126 (1%)

Query: 59  RDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNL 118
           R +++ + HE + L   TQA  +   Q   R +  +L++         + ++ L  E   
Sbjct: 225 RFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTA 284

Query: 119 LLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELL 178
              + Q L + L   E   +   + ++    RE   ++ + +E E+ +      N+QE +
Sbjct: 285 AEQRNQILSQQLQQMEAEHNTLRNTVE--TEREESKILLEKMELEVAERKLSFHNLQEEM 342

Query: 179 KRTIMQ 184
              + Q
Sbjct: 343 HHLLEQ 348


>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
          Length = 1113

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 84/433 (19%), Positives = 176/433 (40%), Gaps = 57/433 (13%)

Query: 14  EYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLA 73
           E ++   T   +S+     S ++   +++E  +N  + Y +  +D + +        QL 
Sbjct: 277 EVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTV------SQLR 330

Query: 74  TETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLERALDAT 133
           +E +  A+R  +D T  + ++L   +S  +E + E +  + E+  L  Q Q+L   L   
Sbjct: 331 SELRE-AKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKR 389

Query: 134 EVPFSITTD-NLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIR-- 190
           E   S+  + N +  +R    ++  DH+  EL      ++ ++ LLK    +   Q+   
Sbjct: 390 EKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLEALLKALKSECQGQMERQ 449

Query: 191 ----------LNREHKETCEMDWSDKMEAYNIDE-TCGRHHSQSTEVQAHPYSTTFQESA 239
                     L +    T +++ + +M    ++E T  +   +S+E      +T+ QE  
Sbjct: 450 MAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTISDLTTSLQEKE 509

Query: 240 STPE-TRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEE 298
              E T A+ T+       R  L    L+ L +    D   +++ +C+A+ L    + + 
Sbjct: 510 RAIEATNAEITK----LRSRVDLKLQELQHLKN--EGDHLRNVQTECEALKLQMTEKDKV 563

Query: 299 LEDARYKLHHHLH-----------------KTLREITDQEHNVAALKQAIKDKEAPLHVA 341
           +E  R ++ +                    +  +EI D+   +  LK     K+A +   
Sbjct: 564 IEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRMELKELKILKDKKDAKIREL 623

Query: 342 QTRL---------YLRSHRPNMELCRDAAQFR--LLSEVEELNMSLTALREKLLEAEQSL 390
           + R+          + +    +   +D  Q R  LL+EV+     L  L E+    +++ 
Sbjct: 624 EARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNF 683

Query: 391 RN-LEDIHMSLEK 402
           RN  E++ M+  K
Sbjct: 684 RNKSEEMEMTTNK 696


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 70/383 (18%), Positives = 144/383 (37%), Gaps = 20/383 (5%)

Query: 59   RDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWK--SELQREMEALAAET 116
            R Q E    + + L  E  A + +    +    G  L+ T+  +  SE+ +  E L  E 
Sbjct: 748  RQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKEL 807

Query: 117  NLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQE 176
             +L  +++  E + +A  V  S+     +  ++ E  N++   +E      A++    +E
Sbjct: 808  QIL--KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFRE 865

Query: 177  LLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQ-----AHPY 231
              +R      ++ +L  +  E  +M   +  +   +++          E+Q     A+  
Sbjct: 866  KDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANEN 925

Query: 232  STTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLA 291
            ++  Q+S      +A+ +Q    +   E       R L D  L    E    QC  +   
Sbjct: 926  ASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELE-RKLSD--LEKKMETSHNQCQELKAR 982

Query: 292  FGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHR 351
            + R   E +    ++  +L KTL +  D+      LK A ++    L   +         
Sbjct: 983  YERATSETKTKHEEILQNLQKTLLDTEDK------LKGAREENSGLLQELEELRKQADKA 1036

Query: 352  PNMELCRDAAQF--RLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTN 409
               +   DA Q   ++  E  E   SL   ++   + +  L  L++ ++   +++     
Sbjct: 1037 KAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE 1096

Query: 410  SLFIDRQKCMAHRTRYPTILQLA 432
             L ++ QK    R    T+ Q A
Sbjct: 1097 LLTVENQKMEEFRKEIETLKQAA 1119


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.128    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,674,202
Number of Sequences: 37866
Number of extensions: 578969
Number of successful extensions: 3924
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 311
Number of HSP's that attempted gapping in prelim test: 3291
Number of HSP's gapped (non-prelim): 856
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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