Guide to the Human Genome
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Search of human proteins with 21389407

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21389407 hexamthylene bis-acetamide inducible 2 [Homo
sapiens]
         (286 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21389407 hexamthylene bis-acetamide inducible 2 [Homo sapiens]     590   e-169
gi|5453682 hexamethylene bis-acetamide inducible 1 [Homo sapiens]     205   4e-53
gi|148746195 trichohyalin [Homo sapiens]                               46   4e-05
gi|45505178 cancer antigen 1 [Homo sapiens]                            42   5e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    40   0.003
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    39   0.005
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    39   0.005
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    39   0.007
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...    39   0.007
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    39   0.007
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    39   0.007
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa...    39   0.007
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa...    39   0.007
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    39   0.007
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...    39   0.007
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             39   0.007
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...    39   0.007
gi|134152708 arginine and glutamate rich 1 [Homo sapiens]              39   0.007
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        38   0.009
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        38   0.009
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         38   0.009
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         38   0.009
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         38   0.009
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         38   0.009
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         38   0.009
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         38   0.009
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    38   0.009
gi|45593136 LISCH protein isoform 3 [Homo sapiens]                     38   0.012
gi|45545424 LISCH protein isoform 2 [Homo sapiens]                     38   0.012
gi|45505163 LISCH protein isoform 1 [Homo sapiens]                     38   0.012

>gi|21389407 hexamthylene bis-acetamide inducible 2 [Homo sapiens]
          Length = 286

 Score =  590 bits (1520), Expect = e-169
 Identities = 286/286 (100%), Positives = 286/286 (100%)

Query: 1   MMATPNQTACNAESPVALEEAKTSGAPGSPQTPPERHDSGGSLPLTPRMESHSEDEDLAG 60
           MMATPNQTACNAESPVALEEAKTSGAPGSPQTPPERHDSGGSLPLTPRMESHSEDEDLAG
Sbjct: 1   MMATPNQTACNAESPVALEEAKTSGAPGSPQTPPERHDSGGSLPLTPRMESHSEDEDLAG 60

Query: 61  AVGGLGWNSRSPRTQSPGGCSAEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQ 120
           AVGGLGWNSRSPRTQSPGGCSAEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQ
Sbjct: 61  AVGGLGWNSRSPRTQSPGGCSAEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQ 120

Query: 121 SQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDG 180
           SQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDG
Sbjct: 121 SQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDG 180

Query: 181 RGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQAC 240
           RGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQAC
Sbjct: 181 RGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQAC 240

Query: 241 TGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGCRCDEEPGT 286
           TGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGCRCDEEPGT
Sbjct: 241 TGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGCRCDEEPGT 286


>gi|5453682 hexamethylene bis-acetamide inducible 1 [Homo sapiens]
          Length = 359

 Score =  205 bits (521), Expect = 4e-53
 Identities = 127/290 (43%), Positives = 160/290 (55%), Gaps = 31/290 (10%)

Query: 5   PNQTACNAESPVALEEAKTSGAPGSPQTPPERHDSGGSLPLTPRMESHSEDEDLAGAVGG 64
           P QT    ES    E  K      S         +GG  P    +E   E E LA     
Sbjct: 73  PLQTQACPESSCLREGEKGQNGDDS--------SAGGDFPPPAEVEPTPEAELLAQPCH- 123

Query: 65  LGWNSRSPRTQSPGGCSAEA------VLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDE 118
              +S + +  +P     E        L +KKHRRRPSK+KRHW+PY +L+W EK++ DE
Sbjct: 124 ---DSEASKLGAPAAGGEEEWGQQQRQLGKKKHRRRPSKKKRHWKPYYKLTWEEKKKFDE 180

Query: 119 RQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS--------- 169
           +QS RASR+R EMFAKGQPVAPYNTTQFLM+D D EEP+L          +         
Sbjct: 181 KQSLRASRIRAEMFAKGQPVAPYNTTQFLMDDHDQEEPDLKTGLYSKRAAAKSDDTSDDD 240

Query: 170 ---SGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQ 226
               G  E G SDG G    EF ++DFSETYER+HTESLQ  SKQEL+++YLELEK LS+
Sbjct: 241 FMEEGGEEDGGSDGMGGDGSEFLQRDFSETYERYHTESLQNMSKQELIKEYLELEKCLSR 300

Query: 227 AEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNRE 276
            E+E  RL+      G    R V EL  E+ RLR EN +L  EN++  ++
Sbjct: 301 MEDENNRLRLESKRLGGDDAR-VRELELELDRLRAENLQLLTENELHRQQ 349


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 54/211 (25%), Positives = 89/211 (42%), Gaps = 46/211 (21%)

Query: 83   EAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYN 142
            E +L  ++ +RR  +R+R +R   +L   E+Q   E   +R  + RE+ + + + +    
Sbjct: 941  EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL-QQE 999

Query: 143  TTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKD-FSETYERFH 201
              Q L  +R+                            R     ++++KD   +  E+  
Sbjct: 1000 EEQLLREEREKRR-------------------------RQEWERQYRKKDELQQEEEQLL 1034

Query: 202  TESLQGRSKQELVRDYLELEKRLSQAEE-------ETRRLQQLQACTGQQSCRQVEELAA 254
             E  + R  QE  R Y E E+ L Q EE       ETRR Q+L     ++  R+ EEL  
Sbjct: 1035 REEREKRRLQERERQYRE-EEELQQEEEQLLGEERETRRRQEL-----ERQYRKEEELQQ 1088

Query: 255  EVQRLRTE--NQRLRQENQMWNREGCRCDEE 283
            E ++L  E   +R RQE +      CR +EE
Sbjct: 1089 EEEQLLREEPEKRRRQERE----RQCREEEE 1115



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 44/191 (23%), Positives = 79/191 (41%), Gaps = 9/191 (4%)

Query: 83   EAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYN 142
            E +L  ++ +RR  +R+R +R   EL   E+Q   E +  R  +  E  + K + +    
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ-E 1089

Query: 143  TTQFLMND-----RDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEF-QRKDFSET 196
              Q L  +     R   E        +         E  +   R     ++ + ++  + 
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149

Query: 197  YERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAE- 255
             E+   E  + R +QEL R Y E E+   + E+  R  Q+ +    ++  R+ EEL  + 
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209

Query: 256  -VQRLRTENQR 265
              QR R E+QR
Sbjct: 1210 RKQRYRDEDQR 1220



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 44/198 (22%), Positives = 85/198 (42%), Gaps = 23/198 (11%)

Query: 95  PSKRKRHWRPYLELSWAEKQQRDERQSQRASRVR----EEMFAKGQPVAPYNTTQFLMND 150
           P +R+R  R   E   AE +++ E+Q +   R R    EE++ + Q             +
Sbjct: 133 PGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE-------REE 185

Query: 151 RDPEEPNLDVPHGISHPGSSGESEAGDSD-----GRGRAHGEFQRKD-----FSETYERF 200
           R  EE  L    G        E +    +      +GR   + QR++     F E  E+ 
Sbjct: 186 RRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245

Query: 201 --HTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQR 258
               E++  + +++L  +  + ++ L + EE+ R+L++ +    +Q   Q ++     Q+
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305

Query: 259 LRTENQRLRQENQMWNRE 276
           LR + +  R+E Q   RE
Sbjct: 306 LRRKQEEERREQQEERRE 323



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 50/205 (24%), Positives = 88/205 (42%), Gaps = 29/205 (14%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           ++ R +  +R++  R   +L   E+Q R E+Q +R  ++R E   + +        Q L 
Sbjct: 370 EERREQQLRREQQLRREQQLR-REQQLRREQQLRREQQLRREQQLRRE--------QQLR 420

Query: 149 NDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGR 208
            ++       +  H   H     E          R     +R++ +E +E       Q R
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDW--LKREEETERHE-------QER 471

Query: 209 SKQELVRDY----------LELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQR 258
            KQ+L RD           LE E+R  Q E   ++L++ Q    +Q  ++ EE     QR
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531

Query: 259 LRTENQRLRQENQMWNREGCRCDEE 283
           LR+E Q+LR+E +    +  + +EE
Sbjct: 532 LRSE-QQLRREQEERREQLLKREEE 555



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 52/213 (24%), Positives = 83/213 (38%), Gaps = 22/213 (10%)

Query: 92  RRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDR 151
           R +  +R+  W    E    E+Q+R E+Q +R    R E   K Q        Q L +++
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE-RLQQRLRSEQ 536

Query: 152 DPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESL----QG 207
                  +    +         E    + R +   E +R    +  E    + L    + 
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596

Query: 208 RSKQELVRDYLEL-------EKRLSQAEEETRRLQQLQACTGQQSCRQV----EELAAEV 256
           R +Q L R+ +E        E+RL + E E  R QQL     Q+  RQ     E+     
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656

Query: 257 QRLRTE------NQRLRQENQMWNREGCRCDEE 283
           QRL+ E       QRL++E++   RE    +EE
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEE 689



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 47/198 (23%), Positives = 77/198 (38%), Gaps = 25/198 (12%)

Query: 82  AEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPY 141
           +E  L R++  RR    KR           EK+   ER+ QR  R +EE           
Sbjct: 534 SEQQLRREQEERREQLLKRE---------EEKRLEQERREQRLKREQEE----------- 573

Query: 142 NTTQFLMNDRDPEEPNL--DVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYER 199
              Q L  + +  +  L  +    +       E E  + + R     + +  +     + 
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633

Query: 200 FHTESLQGRSKQELVRDYLE-LEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQR 258
             +E  + R +Q+L R+  E  E+RL + EEE R  Q+L+     +  R+ +ELA E Q 
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK--REHEEERREQELAEEEQE 691

Query: 259 LRTENQRLRQENQMWNRE 276
              E  + R     W  E
Sbjct: 692 QARERIKSRIPKWQWQLE 709



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 55/239 (23%), Positives = 98/239 (41%), Gaps = 54/239 (22%)

Query: 83   EAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRA-----------SRVRE-E 130
            E  L R++  +R  +R+R +R   EL   +++QR   + QR+           + VR+ +
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239

Query: 131  MFAKGQPVAPYNTTQ-FLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRA----- 184
            ++ KG+    +   +   + DR  ++   D+ H +      GE +  D +   R      
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQ---DLQHLL------GEQQERDREQERRRWQQRD 1290

Query: 185  -------------HGEFQRKDFSETYER--FHTESLQGRSKQELVRDYLELEKRLSQAEE 229
                           E +R+D     E+     E  + R +QE  R + E E+ L + EE
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350

Query: 230  ETRRLQQLQACTGQQSCRQVEE---LAAEVQRLR---TENQRLRQENQMWNREGCRCDE 282
            +  R Q+      ++  R  E+      E QRLR    E + L++E Q+      RC E
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL------RCQE 1403



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 45/185 (24%), Positives = 82/185 (44%), Gaps = 19/185 (10%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFL---MNDRDPEEPNLDVPHGISHPGSS 170
            Q+R+E+Q  R  R R+ +  + Q        +F    +  ++PE   L+    +      
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530

Query: 171  GESEAGDSDGRGRAHGEFQRKD----FSETYERFHTESLQGRSKQELVRDYLELEKRLSQ 226
             +    +   R +  G+ +R+D    F E  +       Q  S+QE  R +   E+++ +
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590

Query: 227  AEEETRRL---QQLQACTGQQSCRQVEELAAEVQRLRTENQRL--RQENQMWNREGCR-- 279
             E+E + +   QQL+   GQQ  RQ  +     ++ R + Q L  R+E Q+  +E  R  
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERD-----RKFREDEQLLQEREEQQLHRQERDRKF 1645

Query: 280  CDEEP 284
             +EEP
Sbjct: 1646 LEEEP 1650



 Score = 36.2 bits (82), Expect = 0.034
 Identities = 46/193 (23%), Positives = 80/193 (41%), Gaps = 13/193 (6%)

Query: 83  EAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQ-RDERQSQRASRVREEMFAKGQPVAPY 141
           E  L R++  RR  + +R  +   E     +QQ R E+Q +R  ++R E   +       
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439

Query: 142 NTTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFH 201
              +     R+ EE    +           E+E  + + R +     Q ++  E + +  
Sbjct: 440 QERREQRLKREQEERRDWLKR-------EEETERHEQERRKQQLKRDQEEERRERWLKLE 492

Query: 202 TESL---QGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQR 258
            E     Q R +Q+L R+  E  ++  + +EE  RLQ  Q    +Q  R+ +E   E   
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQ--QRLRSEQQLRREQEERREQLL 550

Query: 259 LRTENQRLRQENQ 271
            R E +RL QE +
Sbjct: 551 KREEEKRLEQERR 563



 Score = 35.4 bits (80), Expect = 0.058
 Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 23/189 (12%)

Query: 98   RKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPN 157
            R R  +  L+    E+Q+RD  Q +R  + R+  F + + +      +    DR  +E  
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK 1318

Query: 158  LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYER------FHTESLQGRSKQ 211
                  +       +    ++D + R   +  ++   +   R      F  E L+    Q
Sbjct: 1319 Q-----LLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR---HQ 1370

Query: 212  ELVRDYLELEKRLSQAEEETRRL---QQLQACTGQQSCRQVEELAAEVQRLRTENQRL-R 267
            E  R +LE E+RL + E E + L   QQL+    +Q  RQ  +     ++ R E Q+L R
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD-----RKFREEEQQLSR 1425

Query: 268  QENQMWNRE 276
            QE     RE
Sbjct: 1426 QERDRKFRE 1434



 Score = 33.1 bits (74), Expect = 0.29
 Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 15/191 (7%)

Query: 95  PSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPE 154
           P + +   R  LEL    ++ R+E+Q QR  R R++   + +    +   + ++     E
Sbjct: 205 PDEEQLRRRELLEL---RRKGREEKQQQR--RERQDRVFQEEEEKEWRKRETVLRK---E 256

Query: 155 EPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEF--QRKDFSETYERFHTESLQGRSKQE 212
           E  L        P    E +  +   R     E   +R++  +  +R   E  Q R KQE
Sbjct: 257 EEKLQE----EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ-QLRRKQE 311

Query: 213 LVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
             R   + E+R  Q   E +  ++ Q    +Q  R+ ++L  E +  R E Q  R++ + 
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371

Query: 273 WNREGCRCDEE 283
              +  R +++
Sbjct: 372 RREQQLRREQQ 382



 Score = 33.1 bits (74), Expect = 0.29
 Identities = 42/196 (21%), Positives = 82/196 (41%), Gaps = 7/196 (3%)

Query: 89   KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
            ++ +RR  +  R +R   +L   E++++  R+ +R  + REE     +    +   +  +
Sbjct: 1325 REEKRRRQETDRKFREEEQLL-QEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL 1383

Query: 149  NDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGR 208
              ++ E   L     +       E E      R R   E +++   +  +R   E  Q  
Sbjct: 1384 RRQERERKFLKEEQQLR----CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439

Query: 209  SKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQ 268
             +QE  R +LE E++L Q  E  R+ ++ +    ++  +Q+     + + L  E Q  RQ
Sbjct: 1440 RRQERERKFLEEEQQLRQ--ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497

Query: 269  ENQMWNREGCRCDEEP 284
            E     RE     +EP
Sbjct: 1498 ERDRKFREQELRSQEP 1513



 Score = 33.1 bits (74), Expect = 0.29
 Identities = 44/167 (26%), Positives = 71/167 (42%), Gaps = 20/167 (11%)

Query: 114  QQRDERQSQRASRVREEMFAKGQP-VAPYNTTQFLMNDRDP---EEPNLDVPHGISHPGS 169
            Q+R+E+Q  R  R R+  F + +P +      Q L +DRD    EE  L           
Sbjct: 1629 QEREEQQLHRQERDRK--FLEEEPQLRRQEREQQLRHDRDRKFREEEQLL---------Q 1677

Query: 170  SGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEK-RLSQAE 228
             GE +      R R   E +++   +  ER   +  Q   +QEL R + E E+ R    +
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737

Query: 229  EETRRLQQLQACTGQQSCRQVEE----LAAEVQRLRTENQRLRQENQ 271
            E+ RR ++ +    ++  R   E       E  R   E ++LRQE +
Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784



 Score = 31.6 bits (70), Expect = 0.84
 Identities = 52/232 (22%), Positives = 90/232 (38%), Gaps = 54/232 (23%)

Query: 92  RRRPSKRKRHWRPYLELSWAE-----KQQRDERQ----------SQRASRVREEMFAKGQ 136
           RRR  + ++  R   EL W E     +QQ++E Q           +++ R R+ + A+  
Sbjct: 730 RRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR-P 788

Query: 137 PVAPYNTTQFLMNDRD-------PEEPN-----------------LDVPHGISHPGSS-- 170
           P+      Q    +R        PEE                   L+    +     +  
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848

Query: 171 -GESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQEL-----VRDYLELEKRL 224
             E E G  + + R   + QR+D      R+  E  + R +  L     +++ L  E++L
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRD---QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL 905

Query: 225 SQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNRE 276
            Q EEE  + ++ +    Q+  RQ  E   E Q  + E Q LR+E +   R+
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYRE---EEQLQQEEEQLLREEREKRRRQ 954



 Score = 31.6 bits (70), Expect = 0.84
 Identities = 34/195 (17%), Positives = 81/195 (41%), Gaps = 12/195 (6%)

Query: 86   LARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQ 145
            L  ++  RR  + ++  +   +L   E++Q+  +   R  R  E+  ++ +    +   +
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436

Query: 146  FLMNDRDPEEPNLDVPHGIS---HPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHT 202
              +  ++ E   L+    +    H     E +        + H + + + F E  ++   
Sbjct: 1437 QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR 1496

Query: 203  ESLQGRSK------QELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV 256
            +    + +      QE  R +LE E++L + + + + LQ+ Q    Q+  +Q  +   + 
Sbjct: 1497 QERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ---DR 1553

Query: 257  QRLRTENQRLRQENQ 271
             R   E ++LRQE +
Sbjct: 1554 DRKFREEEQLRQERE 1568



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 43/194 (22%), Positives = 78/194 (40%), Gaps = 20/194 (10%)

Query: 92  RRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDR 151
           R R  + ++  R   E     KQ+ + R+ Q   R ++E   + +        Q      
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE---RREQQEERREQQLRREQE 344

Query: 152 DPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQ 211
           +  E  L             E E    + + R   E +R++     E+      Q R +Q
Sbjct: 345 ERREQQL-----------RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393

Query: 212 ELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTE--NQRLRQE 269
           +L R+     ++  + E++ RR QQL+    +Q  R+ +E     Q+   E   QRL++E
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRR---EQQLRREQEEERHEQKHEQERREQRLKRE 450

Query: 270 NQMWNREGCRCDEE 283
            Q   R+  + +EE
Sbjct: 451 -QEERRDWLKREEE 463



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 48/206 (23%), Positives = 79/206 (38%), Gaps = 44/206 (21%)

Query: 89   KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRV-REEMFA-KGQPVAPYNTTQF 146
            ++  R   +R+   R + E    E+Q R ER+ Q+ SR  R+  F  + Q V      + 
Sbjct: 1541 RRQERGQQRRQDRDRKFRE----EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596

Query: 147  LMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
             M D                     E +    +G+ +   E  RK F E  +       Q
Sbjct: 1597 FMED---------------------EQQLRRQEGQQQLRQERDRK-FREDEQLLQEREEQ 1634

Query: 207  GRSKQELVRDYLELEKRLSQAEEET----------RRLQQL------QACTGQQSCRQVE 250
               +QE  R +LE E +L + E E           R  +QL      Q    Q+  R+  
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694

Query: 251  ELAAEVQRLRTENQRLRQENQMWNRE 276
            E   +++R   E + L++E Q+  +E
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQE 1720



 Score = 29.3 bits (64), Expect = 4.1
 Identities = 40/212 (18%), Positives = 87/212 (41%), Gaps = 24/212 (11%)

Query: 83   EAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYN 142
            E  L + + R+   + ++  R   +  + E++Q+  RQ +    + EE   + +    + 
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464

Query: 143  TTQFLMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDF-SETYERFH 201
              + L+ +R+ ++      H         E E      R     +F+ ++  S+  ER  
Sbjct: 1465 EEEQLLQEREEQQL-----HRQERDRKFLEEE--QQLRRQERDRKFREQELRSQEPERKF 1517

Query: 202  TESLQGRSKQELVRDYLELEKRLSQAE----------------EETRRLQQLQACTGQQS 245
             E  Q   +Q+  R +L+ E++L + E                E+ R+ ++ Q  + Q+ 
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577

Query: 246  CRQVEELAAEVQRLRTENQRLRQENQMWNREG 277
             R+      +V+R   E + +  E Q+  +EG
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 11/86 (12%)

Query: 205 LQGRSKQELVRDYLELEKRLSQAEEE-------TRRLQQLQACTGQQSCRQVEELAAEVQ 257
           LQ R ++E   D    E R  Q EEE        R+ Q+ +   G++   + E L  +  
Sbjct: 110 LQDRRQEE---DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERL-EQRD 165

Query: 258 RLRTENQRLRQENQMWNREGCRCDEE 283
           R R + +  RQ  +   RE  R +EE
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEE 191



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E  RK   E   R   E  Q R +QE  R + E E++L Q  EE    QQL++    +  
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLR-RQERDRKFRE-EEQLRQEREE----QQLRSQESDRKF 1797

Query: 247  RQVEELAAEVQRLRTENQRLRQENQMWNREGCRCDEE 283
            R+ E+L  E +  +   Q+ R     W  E  + +E+
Sbjct: 1798 REEEQLRQEREEQQLRPQQ-RDGKYRWEEEQLQLEEQ 1833


>gi|45505178 cancer antigen 1 [Homo sapiens]
          Length = 641

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 28/79 (35%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 198 ERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQ 257
           ER+ TE  Q   K + V  YLE++K LS+ EEE  RLQQL+    + +   ++ L  E +
Sbjct: 286 ERYMTEMQQ---KNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKE 342

Query: 258 RLRTENQRLRQENQMWNRE 276
               E   L++E Q   +E
Sbjct: 343 AQEQEFLSLQEEFQKLEKE 361


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 20/89 (22%), Positives = 49/89 (55%), Gaps = 4/89 (4%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
           Q +   E  E+   +  + R ++E +R   E EK++ + EE+ R  +++     ++   Q
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIR---EQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674

Query: 249 VEELAAEVQRLRTENQRL-RQENQMWNRE 276
            E++  + ++++ + +++ RQE +MW +E
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703



 Score = 37.4 bits (85), Expect = 0.015
 Identities = 23/117 (19%), Positives = 53/117 (45%), Gaps = 25/117 (21%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
           Q +   E  E+   +  + R ++E +R   E E+++ + EE T+  ++      ++ C Q
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIR---EQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 625

Query: 249 VEELAAEVQRLRTENQRLR----------------------QENQMWNREGCRCDEE 283
            E++  + +++R + +++R                      QE +MW +E   C++E
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 9/66 (13%)

Query: 210 KQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQE 269
           K E+  +  EL+++L +A+    + QQLQA        + + L  E+Q +  + Q   +E
Sbjct: 298 KSEIQLNVKELKRKLERAKLLLPQ-QQLQA--------EADHLGKELQSVSAKLQAQVEE 348

Query: 270 NQMWNR 275
           N++WNR
Sbjct: 349 NELWNR 354



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 18/91 (19%), Positives = 46/91 (50%), Gaps = 3/91 (3%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQA---EEETRRLQQLQACTGQQS 245
           Q +   E  E+   +  + R ++E++ +  E  +R  +    +EE  R Q+      ++ 
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439

Query: 246 CRQVEELAAEVQRLRTENQRLRQENQMWNRE 276
            R++EE   E +++R + ++ ++E ++  +E
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQE 470


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 24/107 (22%), Positives = 53/107 (49%), Gaps = 12/107 (11%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLEL--EKRLSQAEEETRRLQQLQACTGQQSC 246
           Q +   E  E+   +  + R ++E +R+  E+  E+     E+E +  +Q +    Q+  
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669

Query: 247 --RQVEELAAEVQRLRTENQRLR--------QENQMWNREGCRCDEE 283
             RQ E++  + +++R + +++R        QE +MW +E   C++E
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 716



 Score = 35.8 bits (81), Expect = 0.044
 Identities = 19/89 (21%), Positives = 47/89 (52%), Gaps = 4/89 (4%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
           Q +   E  E+   +      ++E +R   E EK++ + EE+ R  +++     ++   Q
Sbjct: 652 QEEKMCEQEEKMQEQEETMWRQEEKIR---EQEKKIREQEEKIREQEEMMQEQEEKMWEQ 708

Query: 249 VEELAAEVQRLRTENQRL-RQENQMWNRE 276
            E++  + ++++ + +++ RQE +MW +E
Sbjct: 709 EEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737



 Score = 33.1 bits (74), Expect = 0.29
 Identities = 22/90 (24%), Positives = 48/90 (53%), Gaps = 2/90 (2%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
           Q +   E  E+   +  + R ++E+ R+  ++ ++    EEE R+ Q+ +    ++  R+
Sbjct: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581

Query: 249 VEE-LAAEVQRLR-TENQRLRQENQMWNRE 276
            EE +  + +++R  E +R  QE +MW +E
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611



 Score = 32.7 bits (73), Expect = 0.38
 Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
           Q++   E  E+   +  +   ++E +R   E E+++ + EE+  R  Q +    Q+   +
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIR---EQEEKIREQEEKMWR--QEEKIREQEEMWR 548

Query: 249 VEELAAEVQRLRTENQRLRQENQMWNRE 276
            EE   E +++  E +R  QE++MW +E
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQE 576



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 9/66 (13%)

Query: 210 KQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQE 269
           K E+  +  EL+++L +A+    + QQLQA        + + L  E+Q +  + Q   +E
Sbjct: 237 KSEIQLNVKELKRKLERAKLLLPQ-QQLQA--------EADHLGKELQSVSAKLQAQVEE 287

Query: 270 NQMWNR 275
           N++WNR
Sbjct: 288 NELWNR 293


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 11/117 (9%)

Query: 168 GSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQA 227
           G S   +  D     R   E   +      E     SL  R ++E +R   E E+RL + 
Sbjct: 155 GPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLR---EQEERLHEQ 211

Query: 228 EEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR-QENQMWNREGCRCDEE 283
           EE   RL + +    ++ C Q E L  + +RLR + +RLR QE ++  +E   C++E
Sbjct: 212 EE---RLHEQE----ERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQE 261



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
           Q +   E  ER H +  +   ++E +    E E+RL + EE  R  ++      ++   Q
Sbjct: 197 QEERLREQEERLHEQEERLHEQEERL---CEQEERLCEQEERLREQEERLREQEERLHEQ 253

Query: 249 VEELAAEVQRLRTENQRLRQENQMWNRE 276
            E L  + +RL  + +RL ++ ++  +E
Sbjct: 254 EERLCEQEERLCEQEERLCEQEKLPGQE 281



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 13/101 (12%)

Query: 189 QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEE---ETRRLQQLQACTGQQS 245
           Q +   E  ER H +  +   ++E +    E E+RL + E+   + R L++++    Q+ 
Sbjct: 239 QEERLREQEERLHEQEERLCEQEERL---CEQEERLCEQEKLPGQERLLEEVEKLLEQER 295

Query: 246 CRQVEELAAEVQRLRTE------NQRLRQENQ-MWNREGCR 279
            ++ +E   E +RL  E       +RLRQ+++ +W +E  R
Sbjct: 296 RQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLR 336



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 4/61 (6%)

Query: 219 ELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
           E+EK L   E+E R+ +Q +    ++   +VEEL  E +RLR +++RL Q+  +   E  
Sbjct: 286 EVEKLL---EQERRQEEQERLLERERLLDEVEELL-EQERLRQQDERLWQQETLRELERL 341

Query: 279 R 279
           R
Sbjct: 342 R 342


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           K H +RP+  +    P++     E+Q R + +     R +++   K +    Y+ ++   
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDH-IDRTKKKRGEKDETEYEYSGSEEEE 330

Query: 149 NDRDPEEPN--LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
            + D  EP+  L++P         GES       R     +   K+ SE   R   E  Q
Sbjct: 331 EENDSGEPSSILNLP---------GESTLR----RDFLRLQLANKERSEALRRQQLEQQQ 377

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV-QRLRTENQR 265
             +++   +   E +KR+ + +E+ RRL++ Q    +   +Q  E      +++R E +R
Sbjct: 378 RENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER 437

Query: 266 LRQENQ 271
            R E++
Sbjct: 438 RRAEHE 443


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           K H +RP+  +    P++     E+Q R + +     R +++   K +    Y+ ++   
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDH-IDRTKKKRGEKDETEYEYSGSEEEE 330

Query: 149 NDRDPEEPN--LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
            + D  EP+  L++P         GES       R     +   K+ SE   R   E  Q
Sbjct: 331 EENDSGEPSSILNLP---------GESTLR----RDFLRLQLANKERSEALRRQQLEQQQ 377

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV-QRLRTENQR 265
             +++   +   E +KR+ + +E+ RRL++ Q    +   +Q  E      +++R E +R
Sbjct: 378 RENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER 437

Query: 266 LRQENQ 271
            R E++
Sbjct: 438 RRAEHE 443


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           K H +RP+  +    P++     E+Q R + +     R +++   K +    Y+ ++   
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDH-IDRTKKKRGEKDETEYEYSGSEEEE 330

Query: 149 NDRDPEEPN--LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
            + D  EP+  L++P         GES       R     +   K+ SE   R   E  Q
Sbjct: 331 EENDSGEPSSILNLP---------GESTLR----RDFLRLQLANKERSEALRRQQLEQQQ 377

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV-QRLRTENQR 265
             +++   +   E +KR+ + +E+ RRL++ Q    +   +Q  E      +++R E +R
Sbjct: 378 RENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER 437

Query: 266 LRQENQ 271
            R E++
Sbjct: 438 RRAEHE 443


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           K H +RP+  +    P++     E+Q R + +     R +++   K +    Y+ ++   
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDH-IDRTKKKRGEKDETEYEYSGSEEEE 330

Query: 149 NDRDPEEPN--LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
            + D  EP+  L++P         GES       R     +   K+ SE   R   E  Q
Sbjct: 331 EENDSGEPSSILNLP---------GESTLR----RDFLRLQLANKERSEALRRQQLEQQQ 377

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV-QRLRTENQR 265
             +++   +   E +KR+ + +E+ RRL++ Q    +   +Q  E      +++R E +R
Sbjct: 378 RENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER 437

Query: 266 LRQENQ 271
            R E++
Sbjct: 438 RRAEHE 443


>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
           sapiens]
          Length = 1323

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           K H +RP+  +    P++     E+Q R + +     R +++   K +    Y+ ++   
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDH-IDRTKKKRGEKDETEYEYSGSEEEE 330

Query: 149 NDRDPEEPN--LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
            + D  EP+  L++P         GES       R     +   K+ SE   R   E  Q
Sbjct: 331 EENDSGEPSSILNLP---------GESTLR----RDFLRLQLANKERSEALRRQQLEQQQ 377

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV-QRLRTENQR 265
             +++   +   E +KR+ + +E+ RRL++ Q    +   +Q  E      +++R E +R
Sbjct: 378 RENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER 437

Query: 266 LRQENQ 271
            R E++
Sbjct: 438 RRAEHE 443


>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
           sapiens]
          Length = 1331

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           K H +RP+  +    P++     E+Q R + +     R +++   K +    Y+ ++   
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDH-IDRTKKKRGEKDETEYEYSGSEEEE 330

Query: 149 NDRDPEEPN--LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
            + D  EP+  L++P         GES       R     +   K+ SE   R   E  Q
Sbjct: 331 EENDSGEPSSILNLP---------GESTLR----RDFLRLQLANKERSEALRRQQLEQQQ 377

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV-QRLRTENQR 265
             +++   +   E +KR+ + +E+ RRL++ Q    +   +Q  E      +++R E +R
Sbjct: 378 RENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER 437

Query: 266 LRQENQ 271
            R E++
Sbjct: 438 RRAEHE 443


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           K H +RP+  +    P++     E+Q R + +     R +++   K +    Y+ ++   
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDH-IDRTKKKRGEKDETEYEYSGSEEEE 330

Query: 149 NDRDPEEPN--LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
            + D  EP+  L++P         GES       R     +   K+ SE   R   E  Q
Sbjct: 331 EENDSGEPSSILNLP---------GESTLR----RDFLRLQLANKERSEALRRQQLEQQQ 377

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV-QRLRTENQR 265
             +++   +   E +KR+ + +E+ RRL++ Q    +   +Q  E      +++R E +R
Sbjct: 378 RENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER 437

Query: 266 LRQENQ 271
            R E++
Sbjct: 438 RRAEHE 443


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 41/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%)

Query: 89  KKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLM 148
           K H +RP+  +    P++     E+Q R + +     R +++   K +    Y+ ++   
Sbjct: 272 KNHSQRPATEQLMKHPFIRDQPNERQVRIQLKDH-IDRTKKKRGEKDETEYEYSGSEEEE 330

Query: 149 NDRDPEEPN--LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
            + D  EP+  L++P         GES       R     +   K+ SE   R   E  Q
Sbjct: 331 EENDSGEPSSILNLP---------GESTLR----RDFLRLQLANKERSEALRRQQLEQQQ 377

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEV-QRLRTENQR 265
             +++   +   E +KR+ + +E+ RRL++ Q    +   +Q  E      +++R E +R
Sbjct: 378 RENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEER 437

Query: 266 LRQENQ 271
            R E++
Sbjct: 438 RRAEHE 443


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 22/141 (15%)

Query: 153 PEEPNLDVPHGISHPGSSGESEAGDSD--------GRGRAHGEFQRKDFSETYERFHTES 204
           P    +  P    +  +S ++ AG +D           R     QR+   E  ER   E 
Sbjct: 449 PTPAMVSAPSSTVNASASVKTSAGTTDPEEATRLLAEKRRLAREQRE--KEERERREQEE 506

Query: 205 LQGRSKQELVRDYLELEKRLSQAEEETRRL---------QQLQACTGQQSCRQVEELAAE 255
           L+ + ++EL +   E  +R ++ EEE+RRL         +QLQ    +++ R+ EE A  
Sbjct: 507 LERQKREELAQRVAE--ERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREE-AER 563

Query: 256 VQRLRTENQRLRQENQMWNRE 276
            QR + E  R+R+E +   +E
Sbjct: 564 AQRQKEEEARVREEAERVRQE 584



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 12/137 (8%)

Query: 112 EKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSG 171
           EK++R+ R+ +   R + E  A  Q VA   TT+     R+ E   L+            
Sbjct: 495 EKEERERREQEELERQKREELA--QRVAEERTTR-----REEESRRLEAEQA-REKEEQL 546

Query: 172 ESEAGDSDGRGRAHGE-FQRKDFSETYERFHTESLQGRSKQELVRDY---LELEKRLSQA 227
           + +A +   R R   E  QR+   E   R   E ++   ++   R+    LE +KRL + 
Sbjct: 547 QRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEI 606

Query: 228 EEETRRLQQLQACTGQQ 244
            + TRR +     T  Q
Sbjct: 607 MKRTRRTEATDKKTSDQ 623


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 19/184 (10%)

Query: 98  RKRHWRPYLEL-SWAEKQQRDERQSQRASRVREEM---FAKGQPVAPYNTTQFLMNDRDP 153
           ++R W+  +E  +  E+++RD  + Q   R   E+    AK   +AP   T  +   +D 
Sbjct: 244 QERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDE 303

Query: 154 EEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQEL 213
            +       G+       +S+  ++        E Q++   E  E    + +Q   +QE 
Sbjct: 304 AKHLRQEVEGLE---GKLQSQVENNQALSLLSKE-QKQRLQEQEEMLREQEVQRVREQE- 358

Query: 214 VRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRL-RQENQM 272
                    RL +  E  R  Q+     G++  +Q + L  + +RLR E +RL +QE ++
Sbjct: 359 ---------RLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRL 409

Query: 273 WNRE 276
           W++E
Sbjct: 410 WDQE 413



 Score = 32.7 bits (73), Expect = 0.38
 Identities = 21/91 (23%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 199 RFHTESLQGRSKQELVRDYL------ELEKRLSQAEEETRRLQQLQACTGQQSCRQVEEL 252
           R   E L+G+ + ++  +        E ++RL + EE  R  +  +    ++ C Q E L
Sbjct: 308 RQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERL 367

Query: 253 AAEVQRLRTENQRLRQENQMWNREGCRCDEE 283
             + + L+ + +RLR++ Q   ++  R  +E
Sbjct: 368 REQQKTLQEQGERLRKQEQRLRKQEERLRKE 398


>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
          Length = 273

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 25/193 (12%)

Query: 90  KHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMN 149
           KH ++ S+ +   R    +    K +  +R  +R SR R               T     
Sbjct: 19  KHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRS----------TNTAVSRR 68

Query: 150 DRDPEEPN-----LDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTES 204
           +RD E  +     +D+        SS + +    +   +A  E QRK   +  E    E 
Sbjct: 69  ERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEE 128

Query: 205 LQGRSKQELVRDYL--ELEKRLSQAEEET-RRLQQLQACTGQQSCRQVE-----ELAAEV 256
              R  +ELV   +  ELEKR  + E E  RR+++ +    +Q   ++E     ELAA  
Sbjct: 129 ETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAA-- 186

Query: 257 QRLRTENQRLRQE 269
           Q+ R E +R ++E
Sbjct: 187 QKAREEEERAKRE 199


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 208  RSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR 267
            + +Q LV    E  +R  +AEE  RR Q+      QQ  +Q E LA E QRLR + Q L 
Sbjct: 2543 QERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLE 2602

Query: 268  QENQ 271
            ++++
Sbjct: 2603 EQHR 2606



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 28/181 (15%)

Query: 111  AEKQQRD-ERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS 169
            AEKQ+ + ER+++R  +  E+                 +  R+  E  L+    ++   +
Sbjct: 1662 AEKQKEEAEREARRRGKAEEQA----------------VRQRELAEQELEKQRQLAEGTA 1705

Query: 170  SGESEAGDSDGRGRAH---GEFQRKDFSETYERFHTESLQGRSKQ-----ELVRDYLELE 221
                 A     R RA    GE QR+   E   R   E+     K+     EL +   E+E
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1765

Query: 222  KRLS---QAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
              L+   +AEEE+R   +      +    +  ELA E  RLR   +  +++ Q+   +  
Sbjct: 1766 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1825

Query: 279  R 279
            R
Sbjct: 1826 R 1826



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E ++    + ++    ++ Q R +Q+  +  +E E++   A  E  R +Q +A  G +  
Sbjct: 2510 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-- 2567

Query: 247  RQVEELAAEVQRLRTENQRLRQENQ 271
            R+ EEL    Q+ R + + L +ENQ
Sbjct: 2568 RKQEELQQLEQQRRQQEELLAEENQ 2592



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 189  QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
            Q++  +E   +   +++Q  ++ +   + L+ +K L+Q  E+ RRLQ+ +    QQ   +
Sbjct: 2303 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQLAEE 2360

Query: 249  VE----ELAAEVQR---LRTENQRLRQENQMWNREGCRCDEE 283
             +     L AE QR   +  E +RL+      +R   R +E+
Sbjct: 2361 TQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEED 2402



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 28/117 (23%)

Query: 181  RGRAHGEFQRKDFSETY--ERFHTESLQGRSKQELVRDYLEL-------EKRLSQAEEET 231
            R +   E QRK  +E     R   E+   R KQ  ++   EL       E+RL QAE E 
Sbjct: 1500 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1559

Query: 232  RRLQQLQACTGQQSC-------------------RQVEELAAEVQRLRTENQRLRQE 269
             R  Q+   T Q+S                    R ++E    V +LR E +R  Q+
Sbjct: 1560 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGES 173
            QQ+ E   ++A R++E+     Q +A    TQ      + E          +       +
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2390

Query: 174  EAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRR 233
            E   +  R     +  RK   E  E+ H   L  + K  LV+  LE+++           
Sbjct: 2391 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT-LEIQR----------- 2438

Query: 234  LQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
                     QQS    E L   +  L  E ++L+QE ++
Sbjct: 2439 ---------QQSDHDAERLREAIAELEREKEKLQQEAKL 2468


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 208  RSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR 267
            + +Q LV    E  +R  +AEE  RR Q+      QQ  +Q E LA E QRLR + Q L 
Sbjct: 2547 QERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLE 2606

Query: 268  QENQ 271
            ++++
Sbjct: 2607 EQHR 2610



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 28/181 (15%)

Query: 111  AEKQQRD-ERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS 169
            AEKQ+ + ER+++R  +  E+                 +  R+  E  L+    ++   +
Sbjct: 1666 AEKQKEEAEREARRRGKAEEQA----------------VRQRELAEQELEKQRQLAEGTA 1709

Query: 170  SGESEAGDSDGRGRAH---GEFQRKDFSETYERFHTESLQGRSKQ-----ELVRDYLELE 221
                 A     R RA    GE QR+   E   R   E+     K+     EL +   E+E
Sbjct: 1710 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1769

Query: 222  KRLS---QAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
              L+   +AEEE+R   +      +    +  ELA E  RLR   +  +++ Q+   +  
Sbjct: 1770 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1829

Query: 279  R 279
            R
Sbjct: 1830 R 1830



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E ++    + ++    ++ Q R +Q+  +  +E E++   A  E  R +Q +A  G +  
Sbjct: 2514 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-- 2571

Query: 247  RQVEELAAEVQRLRTENQRLRQENQ 271
            R+ EEL    Q+ R + + L +ENQ
Sbjct: 2572 RKQEELQQLEQQRRQQEELLAEENQ 2596



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 189  QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
            Q++  +E   +   +++Q  ++ +   + L+ +K L+Q  E+ RRLQ+ +    QQ   +
Sbjct: 2307 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQLAEE 2364

Query: 249  VE----ELAAEVQR---LRTENQRLRQENQMWNREGCRCDEE 283
             +     L AE QR   +  E +RL+      +R   R +E+
Sbjct: 2365 TQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEED 2406



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 28/117 (23%)

Query: 181  RGRAHGEFQRKDFSETY--ERFHTESLQGRSKQELVRDYLEL-------EKRLSQAEEET 231
            R +   E QRK  +E     R   E+   R KQ  ++   EL       E+RL QAE E 
Sbjct: 1504 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1563

Query: 232  RRLQQLQACTGQQSC-------------------RQVEELAAEVQRLRTENQRLRQE 269
             R  Q+   T Q+S                    R ++E    V +LR E +R  Q+
Sbjct: 1564 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGES 173
            QQ+ E   ++A R++E+     Q +A    TQ      + E          +       +
Sbjct: 2337 QQQKELAQEQARRLQEDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2394

Query: 174  EAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRR 233
            E   +  R     +  RK   E  E+ H   L  + K  LV+  LE+++           
Sbjct: 2395 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT-LEIQR----------- 2442

Query: 234  LQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
                     QQS    E L   +  L  E ++L+QE ++
Sbjct: 2443 ---------QQSDHDAERLREAIAELEREKEKLQQEAKL 2472


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 208  RSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR 267
            + +Q LV    E  +R  +AEE  RR Q+      QQ  +Q E LA E QRLR + Q L 
Sbjct: 2543 QERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLE 2602

Query: 268  QENQ 271
            ++++
Sbjct: 2603 EQHR 2606



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 28/181 (15%)

Query: 111  AEKQQRD-ERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS 169
            AEKQ+ + ER+++R  +  E+                 +  R+  E  L+    ++   +
Sbjct: 1662 AEKQKEEAEREARRRGKAEEQA----------------VRQRELAEQELEKQRQLAEGTA 1705

Query: 170  SGESEAGDSDGRGRAH---GEFQRKDFSETYERFHTESLQGRSKQ-----ELVRDYLELE 221
                 A     R RA    GE QR+   E   R   E+     K+     EL +   E+E
Sbjct: 1706 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1765

Query: 222  KRLS---QAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
              L+   +AEEE+R   +      +    +  ELA E  RLR   +  +++ Q+   +  
Sbjct: 1766 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1825

Query: 279  R 279
            R
Sbjct: 1826 R 1826



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E ++    + ++    ++ Q R +Q+  +  +E E++   A  E  R +Q +A  G +  
Sbjct: 2510 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-- 2567

Query: 247  RQVEELAAEVQRLRTENQRLRQENQ 271
            R+ EEL    Q+ R + + L +ENQ
Sbjct: 2568 RKQEELQQLEQQRRQQEELLAEENQ 2592



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 189  QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
            Q++  +E   +   +++Q  ++ +   + L+ +K L+Q  E+ RRLQ+ +    QQ   +
Sbjct: 2303 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQLAEE 2360

Query: 249  VE----ELAAEVQR---LRTENQRLRQENQMWNREGCRCDEE 283
             +     L AE QR   +  E +RL+      +R   R +E+
Sbjct: 2361 TQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEED 2402



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 28/117 (23%)

Query: 181  RGRAHGEFQRKDFSETY--ERFHTESLQGRSKQELVRDYLEL-------EKRLSQAEEET 231
            R +   E QRK  +E     R   E+   R KQ  ++   EL       E+RL QAE E 
Sbjct: 1500 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1559

Query: 232  RRLQQLQACTGQQSC-------------------RQVEELAAEVQRLRTENQRLRQE 269
             R  Q+   T Q+S                    R ++E    V +LR E +R  Q+
Sbjct: 1560 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGES 173
            QQ+ E   ++A R++E+     Q +A    TQ      + E          +       +
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2390

Query: 174  EAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRR 233
            E   +  R     +  RK   E  E+ H   L  + K  LV+  LE+++           
Sbjct: 2391 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT-LEIQR----------- 2438

Query: 234  LQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
                     QQS    E L   +  L  E ++L+QE ++
Sbjct: 2439 ---------QQSDHDAERLREAIAELEREKEKLQQEAKL 2468


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 208  RSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR 267
            + +Q LV    E  +R  +AEE  RR Q+      QQ  +Q E LA E QRLR + Q L 
Sbjct: 2511 QERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLE 2570

Query: 268  QENQ 271
            ++++
Sbjct: 2571 EQHR 2574



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 28/181 (15%)

Query: 111  AEKQQRD-ERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS 169
            AEKQ+ + ER+++R  +  E+                 +  R+  E  L+    ++   +
Sbjct: 1630 AEKQKEEAEREARRRGKAEEQA----------------VRQRELAEQELEKQRQLAEGTA 1673

Query: 170  SGESEAGDSDGRGRAH---GEFQRKDFSETYERFHTESLQGRSKQ-----ELVRDYLELE 221
                 A     R RA    GE QR+   E   R   E+     K+     EL +   E+E
Sbjct: 1674 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1733

Query: 222  KRLS---QAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
              L+   +AEEE+R   +      +    +  ELA E  RLR   +  +++ Q+   +  
Sbjct: 1734 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1793

Query: 279  R 279
            R
Sbjct: 1794 R 1794



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E ++    + ++    ++ Q R +Q+  +  +E E++   A  E  R +Q +A  G +  
Sbjct: 2478 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-- 2535

Query: 247  RQVEELAAEVQRLRTENQRLRQENQ 271
            R+ EEL    Q+ R + + L +ENQ
Sbjct: 2536 RKQEELQQLEQQRRQQEELLAEENQ 2560



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 189  QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
            Q++  +E   +   +++Q  ++ +   + L+ +K L+Q  E+ RRLQ+ +    QQ   +
Sbjct: 2271 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQLAEE 2328

Query: 249  VE----ELAAEVQR---LRTENQRLRQENQMWNREGCRCDEE 283
             +     L AE QR   +  E +RL+      +R   R +E+
Sbjct: 2329 TQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEED 2370



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 28/117 (23%)

Query: 181  RGRAHGEFQRKDFSETY--ERFHTESLQGRSKQELVRDYLEL-------EKRLSQAEEET 231
            R +   E QRK  +E     R   E+   R KQ  ++   EL       E+RL QAE E 
Sbjct: 1468 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1527

Query: 232  RRLQQLQACTGQQSC-------------------RQVEELAAEVQRLRTENQRLRQE 269
             R  Q+   T Q+S                    R ++E    V +LR E +R  Q+
Sbjct: 1528 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGES 173
            QQ+ E   ++A R++E+     Q +A    TQ      + E          +       +
Sbjct: 2301 QQQKELAQEQARRLQEDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2358

Query: 174  EAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRR 233
            E   +  R     +  RK   E  E+ H   L  + K  LV+  LE+++           
Sbjct: 2359 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT-LEIQR----------- 2406

Query: 234  LQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
                     QQS    E L   +  L  E ++L+QE ++
Sbjct: 2407 ---------QQSDHDAERLREAIAELEREKEKLQQEAKL 2436


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 208  RSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR 267
            + +Q LV    E  +R  +AEE  RR Q+      QQ  +Q E LA E QRLR + Q L 
Sbjct: 2680 QERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLE 2739

Query: 268  QENQ 271
            ++++
Sbjct: 2740 EQHR 2743



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 28/181 (15%)

Query: 111  AEKQQRD-ERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS 169
            AEKQ+ + ER+++R  +  E+                 +  R+  E  L+    ++   +
Sbjct: 1799 AEKQKEEAEREARRRGKAEEQA----------------VRQRELAEQELEKQRQLAEGTA 1842

Query: 170  SGESEAGDSDGRGRAH---GEFQRKDFSETYERFHTESLQGRSKQ-----ELVRDYLELE 221
                 A     R RA    GE QR+   E   R   E+     K+     EL +   E+E
Sbjct: 1843 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1902

Query: 222  KRLS---QAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
              L+   +AEEE+R   +      +    +  ELA E  RLR   +  +++ Q+   +  
Sbjct: 1903 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1962

Query: 279  R 279
            R
Sbjct: 1963 R 1963



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E ++    + ++    ++ Q R +Q+  +  +E E++   A  E  R +Q +A  G +  
Sbjct: 2647 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-- 2704

Query: 247  RQVEELAAEVQRLRTENQRLRQENQ 271
            R+ EEL    Q+ R + + L +ENQ
Sbjct: 2705 RKQEELQQLEQQRRQQEELLAEENQ 2729



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 189  QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
            Q++  +E   +   +++Q  ++ +   + L+ +K L+Q  E+ RRLQ+ +    QQ   +
Sbjct: 2440 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQLAEE 2497

Query: 249  VE----ELAAEVQR---LRTENQRLRQENQMWNREGCRCDEE 283
             +     L AE QR   +  E +RL+      +R   R +E+
Sbjct: 2498 TQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEED 2539



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 28/117 (23%)

Query: 181  RGRAHGEFQRKDFSETY--ERFHTESLQGRSKQELVRDYLEL-------EKRLSQAEEET 231
            R +   E QRK  +E     R   E+   R KQ  ++   EL       E+RL QAE E 
Sbjct: 1637 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1696

Query: 232  RRLQQLQACTGQQSC-------------------RQVEELAAEVQRLRTENQRLRQE 269
             R  Q+   T Q+S                    R ++E    V +LR E +R  Q+
Sbjct: 1697 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGES 173
            QQ+ E   ++A R++E+     Q +A    TQ      + E          +       +
Sbjct: 2470 QQQKELAQEQARRLQEDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2527

Query: 174  EAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRR 233
            E   +  R     +  RK   E  E+ H   L  + K  LV+  LE+++           
Sbjct: 2528 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT-LEIQR----------- 2575

Query: 234  LQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
                     QQS    E L   +  L  E ++L+QE ++
Sbjct: 2576 ---------QQSDHDAERLREAIAELEREKEKLQQEAKL 2605


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 208  RSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR 267
            + +Q LV    E  +R  +AEE  RR Q+      QQ  +Q E LA E QRLR + Q L 
Sbjct: 2521 QERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLE 2580

Query: 268  QENQ 271
            ++++
Sbjct: 2581 EQHR 2584



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 28/181 (15%)

Query: 111  AEKQQRD-ERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS 169
            AEKQ+ + ER+++R  +  E+                 +  R+  E  L+    ++   +
Sbjct: 1640 AEKQKEEAEREARRRGKAEEQA----------------VRQRELAEQELEKQRQLAEGTA 1683

Query: 170  SGESEAGDSDGRGRAH---GEFQRKDFSETYERFHTESLQGRSKQ-----ELVRDYLELE 221
                 A     R RA    GE QR+   E   R   E+     K+     EL +   E+E
Sbjct: 1684 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1743

Query: 222  KRLS---QAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
              L+   +AEEE+R   +      +    +  ELA E  RLR   +  +++ Q+   +  
Sbjct: 1744 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1803

Query: 279  R 279
            R
Sbjct: 1804 R 1804



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E ++    + ++    ++ Q R +Q+  +  +E E++   A  E  R +Q +A  G +  
Sbjct: 2488 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-- 2545

Query: 247  RQVEELAAEVQRLRTENQRLRQENQ 271
            R+ EEL    Q+ R + + L +ENQ
Sbjct: 2546 RKQEELQQLEQQRRQQEELLAEENQ 2570



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 189  QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
            Q++  +E   +   +++Q  ++ +   + L+ +K L+Q  E+ RRLQ+ +    QQ   +
Sbjct: 2281 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQLAEE 2338

Query: 249  VE----ELAAEVQR---LRTENQRLRQENQMWNREGCRCDEE 283
             +     L AE QR   +  E +RL+      +R   R +E+
Sbjct: 2339 TQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEED 2380



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 28/117 (23%)

Query: 181  RGRAHGEFQRKDFSETY--ERFHTESLQGRSKQELVRDYLEL-------EKRLSQAEEET 231
            R +   E QRK  +E     R   E+   R KQ  ++   EL       E+RL QAE E 
Sbjct: 1478 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1537

Query: 232  RRLQQLQACTGQQSC-------------------RQVEELAAEVQRLRTENQRLRQE 269
             R  Q+   T Q+S                    R ++E    V +LR E +R  Q+
Sbjct: 1538 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGES 173
            QQ+ E   ++A R++E+     Q +A    TQ      + E          +       +
Sbjct: 2311 QQQKELAQEQARRLQEDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2368

Query: 174  EAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRR 233
            E   +  R     +  RK   E  E+ H   L  + K  LV+  LE+++           
Sbjct: 2369 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT-LEIQR----------- 2416

Query: 234  LQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
                     QQS    E L   +  L  E ++L+QE ++
Sbjct: 2417 ---------QQSDHDAERLREAIAELEREKEKLQQEAKL 2446


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 208  RSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR 267
            + +Q LV    E  +R  +AEE  RR Q+      QQ  +Q E LA E QRLR + Q L 
Sbjct: 2529 QERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLE 2588

Query: 268  QENQ 271
            ++++
Sbjct: 2589 EQHR 2592



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 28/181 (15%)

Query: 111  AEKQQRD-ERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS 169
            AEKQ+ + ER+++R  +  E+                 +  R+  E  L+    ++   +
Sbjct: 1648 AEKQKEEAEREARRRGKAEEQA----------------VRQRELAEQELEKQRQLAEGTA 1691

Query: 170  SGESEAGDSDGRGRAH---GEFQRKDFSETYERFHTESLQGRSKQ-----ELVRDYLELE 221
                 A     R RA    GE QR+   E   R   E+     K+     EL +   E+E
Sbjct: 1692 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1751

Query: 222  KRLS---QAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
              L+   +AEEE+R   +      +    +  ELA E  RLR   +  +++ Q+   +  
Sbjct: 1752 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1811

Query: 279  R 279
            R
Sbjct: 1812 R 1812



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E ++    + ++    ++ Q R +Q+  +  +E E++   A  E  R +Q +A  G +  
Sbjct: 2496 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-- 2553

Query: 247  RQVEELAAEVQRLRTENQRLRQENQ 271
            R+ EEL    Q+ R + + L +ENQ
Sbjct: 2554 RKQEELQQLEQQRRQQEELLAEENQ 2578



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 189  QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
            Q++  +E   +   +++Q  ++ +   + L+ +K L+Q  E+ RRLQ+ +    QQ   +
Sbjct: 2289 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQLAEE 2346

Query: 249  VE----ELAAEVQR---LRTENQRLRQENQMWNREGCRCDEE 283
             +     L AE QR   +  E +RL+      +R   R +E+
Sbjct: 2347 TQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEED 2388



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 28/117 (23%)

Query: 181  RGRAHGEFQRKDFSETY--ERFHTESLQGRSKQELVRDYLEL-------EKRLSQAEEET 231
            R +   E QRK  +E     R   E+   R KQ  ++   EL       E+RL QAE E 
Sbjct: 1486 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1545

Query: 232  RRLQQLQACTGQQSC-------------------RQVEELAAEVQRLRTENQRLRQE 269
             R  Q+   T Q+S                    R ++E    V +LR E +R  Q+
Sbjct: 1546 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1602



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGES 173
            QQ+ E   ++A R++E+     Q +A    TQ      + E          +       +
Sbjct: 2319 QQQKELAQEQARRLQEDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2376

Query: 174  EAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRR 233
            E   +  R     +  RK   E  E+ H   L  + K  LV+  LE+++           
Sbjct: 2377 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT-LEIQR----------- 2424

Query: 234  LQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
                     QQS    E L   +  L  E ++L+QE ++
Sbjct: 2425 ---------QQSDHDAERLREAIAELEREKEKLQQEAKL 2454


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 208  RSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLR 267
            + +Q LV    E  +R  +AEE  RR Q+      QQ  +Q E LA E QRLR + Q L 
Sbjct: 2570 QERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLE 2629

Query: 268  QENQ 271
            ++++
Sbjct: 2630 EQHR 2633



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 28/181 (15%)

Query: 111  AEKQQRD-ERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGS 169
            AEKQ+ + ER+++R  +  E+                 +  R+  E  L+    ++   +
Sbjct: 1689 AEKQKEEAEREARRRGKAEEQA----------------VRQRELAEQELEKQRQLAEGTA 1732

Query: 170  SGESEAGDSDGRGRAH---GEFQRKDFSETYERFHTESLQGRSKQ-----ELVRDYLELE 221
                 A     R RA    GE QR+   E   R   E+     K+     EL +   E+E
Sbjct: 1733 QQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEME 1792

Query: 222  KRLS---QAEEETRRLQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQMWNREGC 278
              L+   +AEEE+R   +      +    +  ELA E  RLR   +  +++ Q+   +  
Sbjct: 1793 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAA 1852

Query: 279  R 279
            R
Sbjct: 1853 R 1853



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 22/85 (25%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 187  EFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSC 246
            E ++    + ++    ++ Q R +Q+  +  +E E++   A  E  R +Q +A  G +  
Sbjct: 2537 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVR-- 2594

Query: 247  RQVEELAAEVQRLRTENQRLRQENQ 271
            R+ EEL    Q+ R + + L +ENQ
Sbjct: 2595 RKQEELQQLEQQRRQQEELLAEENQ 2619



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 189  QRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRRLQQLQACTGQQSCRQ 248
            Q++  +E   +   +++Q  ++ +   + L+ +K L+Q  E+ RRLQ+ +    QQ   +
Sbjct: 2330 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQLAEE 2387

Query: 249  VE----ELAAEVQR---LRTENQRLRQENQMWNREGCRCDEE 283
             +     L AE QR   +  E +RL+      +R   R +E+
Sbjct: 2388 TQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEED 2429



 Score = 28.5 bits (62), Expect = 7.1
 Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 28/117 (23%)

Query: 181  RGRAHGEFQRKDFSETY--ERFHTESLQGRSKQELVRDYLEL-------EKRLSQAEEET 231
            R +   E QRK  +E     R   E+   R KQ  ++   EL       E+RL QAE E 
Sbjct: 1527 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVER 1586

Query: 232  RRLQQLQACTGQQSC-------------------RQVEELAAEVQRLRTENQRLRQE 269
             R  Q+   T Q+S                    R ++E    V +LR E +R  Q+
Sbjct: 1587 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1643



 Score = 28.1 bits (61), Expect = 9.2
 Identities = 34/159 (21%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 114  QQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLDVPHGISHPGSSGES 173
            QQ+ E   ++A R++E+     Q +A    TQ      + E          +       +
Sbjct: 2360 QQQKELAQEQARRLQEDKEQMAQQLA--EETQGFQRTLEAERQRQLEMSAEAERLKLRVA 2417

Query: 174  EAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQAEEETRR 233
            E   +  R     +  RK   E  E+ H   L  + K  LV+  LE+++           
Sbjct: 2418 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT-LEIQR----------- 2465

Query: 234  LQQLQACTGQQSCRQVEELAAEVQRLRTENQRLRQENQM 272
                     QQS    E L   +  L  E ++L+QE ++
Sbjct: 2466 ---------QQSDHDAERLREAIAELEREKEKLQQEAKL 2495


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
           domain 1 [Homo sapiens]
          Length = 1412

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 16/95 (16%)

Query: 168 GSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQGRSKQELVRDYLELEKRLSQ- 226
           G  GE+E G++  RG A  + Q  D              GR   + + +Y+  E+  ++ 
Sbjct: 658 GREGEAERGEARARGEAQSQNQATD--------------GREGGKALEEYITQERNRAKE 703

Query: 227 -AEEETRRLQQLQACTGQQSCRQVEELAAEVQRLR 260
             EEE +R+Q+L++   QQ     + +  E  R++
Sbjct: 704 TLEEERKRMQELESLLAQQKKALAKSITQEKNRVK 738


>gi|45593136 LISCH protein isoform 3 [Homo sapiens]
          Length = 581

 Score = 37.7 bits (86), Expect = 0.012
 Identities = 55/211 (26%), Positives = 75/211 (35%), Gaps = 20/211 (9%)

Query: 28  GSPQTPPERHDSGGSLPLTPRMESHSEDEDLAGAVGGLGWNSRSPRTQSPGGC-SAEAVL 86
           G   TP    + GG  P +PR      D++ A    G GW +R PR +S           
Sbjct: 381 GPALTPIRDEEWGGHSPRSPR----GWDQEPAREQAGGGWRARRPRARSVDALDDLTPPS 436

Query: 87  ARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQF 146
             +   R P+      R Y+       + RD+   Q  SR   +      P    +   F
Sbjct: 437 TAESGSRSPTSNGGRSRAYMP---PRSRSRDDLYDQDDSR---DFPRSRDP----HYDDF 486

Query: 147 LMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
              +R P +P     H    P  +G S +GD    GR   E  RK  SE   R H E  +
Sbjct: 487 RSRERPPADPR-SHHHRTRDPRDNG-SRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEE 544

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQL 237
                     Y E +   SQA  E R  + L
Sbjct: 545 EAYYPPAPPPYSETD---SQASRERRLKKNL 572


>gi|45545424 LISCH protein isoform 2 [Homo sapiens]
          Length = 649

 Score = 37.7 bits (86), Expect = 0.012
 Identities = 55/211 (26%), Positives = 75/211 (35%), Gaps = 20/211 (9%)

Query: 28  GSPQTPPERHDSGGSLPLTPRMESHSEDEDLAGAVGGLGWNSRSPRTQSPGGC-SAEAVL 86
           G   TP    + GG  P +PR      D++ A    G GW +R PR +S           
Sbjct: 449 GPALTPIRDEEWGGHSPRSPR----GWDQEPAREQAGGGWRARRPRARSVDALDDLTPPS 504

Query: 87  ARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQF 146
             +   R P+      R Y+       + RD+   Q  SR   +      P    +   F
Sbjct: 505 TAESGSRSPTSNGGRSRAYMP---PRSRSRDDLYDQDDSR---DFPRSRDP----HYDDF 554

Query: 147 LMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
              +R P +P     H    P  +G S +GD    GR   E  RK  SE   R H E  +
Sbjct: 555 RSRERPPADPR-SHHHRTRDPRDNG-SRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEE 612

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQL 237
                     Y E +   SQA  E R  + L
Sbjct: 613 EAYYPPAPPPYSETD---SQASRERRLKKNL 640


>gi|45505163 LISCH protein isoform 1 [Homo sapiens]
          Length = 630

 Score = 37.7 bits (86), Expect = 0.012
 Identities = 55/211 (26%), Positives = 75/211 (35%), Gaps = 20/211 (9%)

Query: 28  GSPQTPPERHDSGGSLPLTPRMESHSEDEDLAGAVGGLGWNSRSPRTQSPGGC-SAEAVL 86
           G   TP    + GG  P +PR      D++ A    G GW +R PR +S           
Sbjct: 430 GPALTPIRDEEWGGHSPRSPR----GWDQEPAREQAGGGWRARRPRARSVDALDDLTPPS 485

Query: 87  ARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQF 146
             +   R P+      R Y+       + RD+   Q  SR   +      P    +   F
Sbjct: 486 TAESGSRSPTSNGGRSRAYMP---PRSRSRDDLYDQDDSR---DFPRSRDP----HYDDF 535

Query: 147 LMNDRDPEEPNLDVPHGISHPGSSGESEAGDSDGRGRAHGEFQRKDFSETYERFHTESLQ 206
              +R P +P     H    P  +G S +GD    GR   E  RK  SE   R H E  +
Sbjct: 536 RSRERPPADPR-SHHHRTRDPRDNG-SRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEE 593

Query: 207 GRSKQELVRDYLELEKRLSQAEEETRRLQQL 237
                     Y E +   SQA  E R  + L
Sbjct: 594 EAYYPPAPPPYSETD---SQASRERRLKKNL 621


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,342,753
Number of Sequences: 37866
Number of extensions: 687175
Number of successful extensions: 5339
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 344
Number of HSP's that attempted gapping in prelim test: 4289
Number of HSP's gapped (non-prelim): 1202
length of query: 286
length of database: 18,247,518
effective HSP length: 101
effective length of query: 185
effective length of database: 14,423,052
effective search space: 2668264620
effective search space used: 2668264620
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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