Guide to the Human Genome
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Search of human proteins with 21361944

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361944 phospholipase A2, group XIIA [Homo sapiens]
         (189 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361944 phospholipase A2, group XIIA [Homo sapiens]               404   e-113
gi|45505135 phospholipase A2, group XIIB [Homo sapiens]               173   7e-44
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        32   0.25 
gi|56237021 fibrillin 3 precursor [Homo sapiens]                       30   1.2  
gi|4505847 phospholipase A2 group IB [Homo sapiens]                    30   1.6  
gi|31791016 keratin associated protein 21-2 [Homo sapiens]             30   1.6  
gi|55770832 cerebellar degeneration-related protein 2 [Homo sapi...    29   2.8  
gi|142976884 phospholipase A2, group III precursor [Homo sapiens]      29   2.8  
gi|83035136 F-box protein 31 [Homo sapiens]                            28   4.7  
gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]           28   6.1  
gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]           28   6.1  
gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo ...    28   6.1  
gi|32698786 zinc finger protein 227 [Homo sapiens]                     28   6.1  
gi|66571327 ring finger protein 213 [Homo sapiens]                     28   6.1  
gi|24041035 notch 2 preproprotein [Homo sapiens]                       27   8.0  

>gi|21361944 phospholipase A2, group XIIA [Homo sapiens]
          Length = 189

 Score =  404 bits (1038), Expect = e-113
 Identities = 189/189 (100%), Positives = 189/189 (100%)

Query: 1   MALLSRPALTLLLLLMAAVVRCQEQAQTTDWRATLKTIRNGVHKIDTYLNAALDLLGGED 60
           MALLSRPALTLLLLLMAAVVRCQEQAQTTDWRATLKTIRNGVHKIDTYLNAALDLLGGED
Sbjct: 1   MALLSRPALTLLLLLMAAVVRCQEQAQTTDWRATLKTIRNGVHKIDTYLNAALDLLGGED 60

Query: 61  GLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKS 120
           GLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKS
Sbjct: 61  GLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKS 120

Query: 121 KNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPYLDSQRAACR 180
           KNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPYLDSQRAACR
Sbjct: 121 KNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPYLDSQRAACR 180

Query: 181 CHYEEKTDL 189
           CHYEEKTDL
Sbjct: 181 CHYEEKTDL 189


>gi|45505135 phospholipase A2, group XIIB [Homo sapiens]
          Length = 195

 Score =  173 bits (439), Expect = 7e-44
 Identities = 77/166 (46%), Positives = 117/166 (70%), Gaps = 7/166 (4%)

Query: 29  TDWRATLKTIRNGVHKIDTYLNAALDLLGGEDGLCQYKCSDGSKPFPRYGYKPSPPNGCG 88
           +DW   L+ +R     +++Y ++ L+LLGG++G+CQY+C  G  P PR GYKP  PNGCG
Sbjct: 32  SDWG--LRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCG 89

Query: 89  SPLFGVH----LNIGIPSLTKCCNQHDRCYETCGKSKNDCDEEFQYCLSKICRDVQKTLG 144
           S   G+     +++GIP++TKCCNQ D CY+TCG +K  CD +F++CL  IC D++++LG
Sbjct: 90  SYFLGLKVPESMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLG 149

Query: 145 LTQHVQ-ACETTVELLFDSVIHLGCKPYLDSQRAACRCHYEEKTDL 189
               V+ AC++ V+ +F++V  LGC+P+++SQRAAC C  EEK +L
Sbjct: 150 FVSKVEAACDSLVDTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL 195


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 32.3 bits (72), Expect = 0.25
 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 12/75 (16%)

Query: 79   YKPSPPNG-CGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKSKNDCDEEFQYCLSKICR 137
            + P PP   CG    G++  +G   LT+ C+Q  RC  TC  S+    E F     ++C 
Sbjct: 2643 WHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQ--RC--TCASSRILLCEPFSCRAGEVC- 2697

Query: 138  DVQKTLGLTQHVQAC 152
                TLG   H Q C
Sbjct: 2698 ----TLG--NHTQGC 2706


>gi|56237021 fibrillin 3 precursor [Homo sapiens]
          Length = 2809

 Score = 30.0 bits (66), Expect = 1.2
 Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 14/63 (22%)

Query: 67   CSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKSKNDCDE 126
            C  G +P P  G   +  N C +           P L  C N   RC  T G  + DCDE
Sbjct: 2236 CPPGMRPLPGSGEGCTDDNECHAQ----------PDL--CVN--GRCVNTAGSFRCDCDE 2281

Query: 127  EFQ 129
             FQ
Sbjct: 2282 GFQ 2284


>gi|4505847 phospholipase A2 group IB [Homo sapiens]
          Length = 148

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 18/50 (36%), Positives = 20/50 (40%), Gaps = 7/50 (14%)

Query: 70  GSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGK 119
           GS PF  Y        GC   L G      +  L KCC  HD CY+   K
Sbjct: 37  GSDPFLEYNNY-----GCYCGLGGS--GTPVDELDKCCQTHDNCYDQAKK 79


>gi|31791016 keratin associated protein 21-2 [Homo sapiens]
          Length = 83

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 18/58 (31%), Positives = 20/58 (34%), Gaps = 3/58 (5%)

Query: 63  CQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKS 120
           C Y C  GS      GY      GCG   +G     G    + CC     CY  C  S
Sbjct: 27  CGYGCGYGSGCRYGSGYGTGCGYGCG---YGSGCGYGCGYSSSCCGYRPLCYRRCYSS 81


>gi|55770832 cerebellar degeneration-related protein 2 [Homo
           sapiens]
          Length = 454

 Score = 28.9 bits (63), Expect = 2.8
 Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 2/91 (2%)

Query: 95  HLNIGIPSLTKCCNQHDRCYETCGKSKNDCDEEFQYCLSKICRDVQKTLGLTQHVQACET 154
           +L   +  L +   QH + YE    +  + +E  Q  ++      QK L LT+ ++  +T
Sbjct: 65  YLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQT 124

Query: 155 TVELLFDSVIHLGCKPYLDSQRAACRCHYEE 185
            ++ L   V  L  K     +R+  +C  E+
Sbjct: 125 NIDHLQSQVEEL--KSSGQGRRSPGKCDQEK 153


>gi|142976884 phospholipase A2, group III precursor [Homo sapiens]
          Length = 509

 Score = 28.9 bits (63), Expect = 2.8
 Identities = 16/55 (29%), Positives = 20/55 (36%), Gaps = 15/55 (27%)

Query: 106 CCNQHDRC---------------YETCGKSKNDCDEEFQYCLSKICRDVQKTLGL 145
           CC +HDRC               Y     S  DCD  FQ CL      +   +G+
Sbjct: 180 CCREHDRCPQNISPLQYNYGIRNYRFHTISHCDCDTRFQQCLQNQHDSISDIVGV 234


>gi|83035136 F-box protein 31 [Homo sapiens]
          Length = 539

 Score = 28.1 bits (61), Expect = 4.7
 Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 9/85 (10%)

Query: 67  CSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKSKNDCDE 126
           C+  S P PR      PP      +F       +PSL + C +  R   T    +  C E
Sbjct: 55  CAGPSPPPPRCSLLELPPELLVE-IFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCRE 113

Query: 127 EFQYC--LSKI------CRDVQKTL 143
           E+  C  L K+      CRDV   L
Sbjct: 114 EYGVCENLRKLEITGVSCRDVYAKL 138


>gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]
          Length = 1119

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 16/118 (13%)

Query: 65  YKCSDGSKPFPRY-----------GYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRC 113
           YKC +  K F  +           G KP     CG   F     + +  +     +  +C
Sbjct: 551 YKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKA-FKWSSKLTVHKVIHTAEKPCKC 609

Query: 114 YETCGKSKNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPY 171
            E CGKS        ++   K+    +K     + V+A  +   L+   VIH G KPY
Sbjct: 610 -EECGKSFKHFSALRKH---KVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPY 663


>gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]
          Length = 1119

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 16/118 (13%)

Query: 65  YKCSDGSKPFPRY-----------GYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRC 113
           YKC +  K F  +           G KP     CG   F     + +  +     +  +C
Sbjct: 551 YKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKA-FKWSSKLTVHKVIHTAEKPCKC 609

Query: 114 YETCGKSKNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPY 171
            E CGKS        ++   K+    +K     + V+A  +   L+   VIH G KPY
Sbjct: 610 -EECGKSFKHFSALRKH---KVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPY 663


>gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo
           sapiens]
          Length = 1119

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 16/118 (13%)

Query: 65  YKCSDGSKPFPRY-----------GYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRC 113
           YKC +  K F  +           G KP     CG   F     + +  +     +  +C
Sbjct: 551 YKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKA-FKWSSKLTVHKVIHTAEKPCKC 609

Query: 114 YETCGKSKNDCDEEFQYCLSKICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPY 171
            E CGKS        ++   K+    +K     + V+A  +   L+   VIH G KPY
Sbjct: 610 -EECGKSFKHFSALRKH---KVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPY 663


>gi|32698786 zinc finger protein 227 [Homo sapiens]
          Length = 799

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 38/146 (26%), Positives = 53/146 (36%), Gaps = 30/146 (20%)

Query: 68  SDGSKPFPRYGYKPSPPNGCG-----SPLFGVHLNIGIPSLTKCCNQ--HDRCYETC--G 118
           SDGS      G KP P   CG     SP   +H N+      KC +Q  H R ++    G
Sbjct: 236 SDGSNQKLPLGEKPHPCGECGRGFSYSPRLPLHPNVHTGE--KCFSQSSHLRTHQRIHPG 293

Query: 119 KSKNDCDEEFQYCLSKICRDVQKTLGLTQHVQACE-------TTVELLFDSVIHLGCKPY 171
           +  N C E    C +K      ++    +    C+       ++  L+     H G KPY
Sbjct: 294 EKLNRCHESGD-CFNKSSFHSYQSNHTGEKSYRCDSCGKGFSSSTGLIIHYRTHTGEKPY 352

Query: 172 LDSQRAAC-----------RCHYEEK 186
              +   C           R H EEK
Sbjct: 353 KCEECGKCFSQSSNFQCHQRVHTEEK 378


>gi|66571327 ring finger protein 213 [Homo sapiens]
          Length = 3280

 Score = 27.7 bits (60), Expect = 6.1
 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 9/67 (13%)

Query: 125  DEEF-QYCLS----KICRDVQKTLGLTQHVQACETTVELLFDSVIHLGCKPYLD----SQ 175
            D+E+ Q C +    KIC +  K + L       E+  + L    +HLG + Y+D    + 
Sbjct: 1150 DQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTH 1209

Query: 176  RAACRCH 182
            R  CR H
Sbjct: 1210 RVKCRVH 1216


>gi|24041035 notch 2 preproprotein [Homo sapiens]
          Length = 2471

 Score = 27.3 bits (59), Expect = 8.0
 Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 9/45 (20%)

Query: 103 LTKCCNQHDRCYETCGK---------SKNDCDEEFQYCLSKICRD 138
           ++K C  H  C+ T G          S  DC+E+   CL+  C++
Sbjct: 878 ISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQN 922


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,135,058
Number of Sequences: 37866
Number of extensions: 401982
Number of successful extensions: 998
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 979
Number of HSP's gapped (non-prelim): 26
length of query: 189
length of database: 18,247,518
effective HSP length: 96
effective length of query: 93
effective length of database: 14,612,382
effective search space: 1358951526
effective search space used: 1358951526
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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