BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21361684 G patch domain containing 1 [Homo sapiens] (931 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21361684 G patch domain containing 1 [Homo sapiens] 1873 0.0 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 53 2e-06 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 53 2e-06 gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 53 2e-06 gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 52 3e-06 gi|56090620 NFKB activating protein-like [Homo sapiens] 52 3e-06 gi|168229156 NFKB activating protein [Homo sapiens] 52 3e-06 gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 52 3e-06 gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 52 3e-06 gi|221219020 NYD-SP11 protein [Homo sapiens] 51 4e-06 gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 51 4e-06 gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 51 4e-06 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 6e-06 gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 50 7e-06 gi|217330641 IWS1 homolog [Homo sapiens] 50 7e-06 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 50 1e-05 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 50 1e-05 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 49 2e-05 gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 49 2e-05 gi|39932583 hypothetical protein LOC55051 isoform 1 [Homo sapiens] 49 2e-05 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 49 3e-05 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 49 3e-05 gi|4507347 TBP-associated factor 2 [Homo sapiens] 49 3e-05 gi|8923271 coiled-coil domain containing 49 [Homo sapiens] 48 4e-05 gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 48 5e-05 gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 47 6e-05 gi|40068059 CBF1 interacting corepressor [Homo sapiens] 47 8e-05 gi|11067749 bromodomain containing protein 3 [Homo sapiens] 47 8e-05 gi|42718020 retinitis pigmentosa 9 [Homo sapiens] 47 8e-05 gi|87299628 biorientation of chromosomes in cell division 1-like... 47 1e-04 >gi|21361684 G patch domain containing 1 [Homo sapiens] Length = 931 Score = 1873 bits (4851), Expect = 0.0 Identities = 931/931 (100%), Positives = 931/931 (100%) Query: 1 MAARDSDSEEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAG 60 MAARDSDSEEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAG Sbjct: 1 MAARDSDSEEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAG 60 Query: 61 YFNTVGSKEGWTPSTFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKT 120 YFNTVGSKEGWTPSTFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKT Sbjct: 61 YFNTVGSKEGWTPSTFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKT 120 Query: 121 KDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPR 180 KDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPR Sbjct: 121 KDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPR 180 Query: 181 RQKPDPGVKIYGCALPPGSSEGSEGEDDDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKG 240 RQKPDPGVKIYGCALPPGSSEGSEGEDDDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKG Sbjct: 181 RQKPDPGVKIYGCALPPGSSEGSEGEDDDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKG 240 Query: 241 LDPHQALFGTSGEHFNLFSGGSERAGDLGEIGLNKGRKLGISGQAFGVGALEEEDDDIYA 300 LDPHQALFGTSGEHFNLFSGGSERAGDLGEIGLNKGRKLGISGQAFGVGALEEEDDDIYA Sbjct: 241 LDPHQALFGTSGEHFNLFSGGSERAGDLGEIGLNKGRKLGISGQAFGVGALEEEDDDIYA 300 Query: 301 TETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKK 360 TETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKK Sbjct: 301 TETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKK 360 Query: 361 IYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAE 420 IYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAE Sbjct: 361 IYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAE 420 Query: 421 LLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAA 480 LLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAA Sbjct: 421 LLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAA 480 Query: 481 AAGHCSWNMALGGGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMT 540 AAGHCSWNMALGGGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMT Sbjct: 481 AAGHCSWNMALGGGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMT 540 Query: 541 EWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKM 600 EWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKM Sbjct: 541 EWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKM 600 Query: 601 KMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLP 660 KMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLP Sbjct: 601 KMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLP 660 Query: 661 TTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNK 720 TTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNK Sbjct: 661 TTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNK 720 Query: 721 EEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ 780 EEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ Sbjct: 721 EEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ 780 Query: 781 AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCP 840 AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCP Sbjct: 781 AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCP 840 Query: 841 NARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS 900 NARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS Sbjct: 841 NARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS 900 Query: 901 DSSDSQSDEETADVSPQELLRRLKSLPLRRQ 931 DSSDSQSDEETADVSPQELLRRLKSLPLRRQ Sbjct: 901 DSSDSQSDEETADVSPQELLRRLKSLPLRRQ 931 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 52.8 bits (125), Expect = 2e-06 Identities = 27/88 (30%), Positives = 46/88 (52%) Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSS 903 +T E +KE +K K K K K++ ++KK K+ + RK K + ++K K+ K E Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77 Query: 904 DSQSDEETADVSPQELLRRLKSLPLRRQ 931 + + +EE + +E RR K RR+ Sbjct: 78 EEEEEEEEKEEEEKEEGRRRKKKKKRRR 105 Score = 48.1 bits (113), Expect = 4e-05 Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 7/95 (7%) Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQK-------NKKPEKSSS 896 +T E + E+ ++ + K K K++ +RK+++KKK K K K+K +K +K Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71 Query: 897 SESSDSSDSQSDEETADVSPQELLRRLKSLPLRRQ 931 E + + + +EE + +E RR K RR+ Sbjct: 72 EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106 Score = 38.5 bits (88), Expect = 0.029 Identities = 17/59 (28%), Positives = 33/59 (55%) Query: 852 EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910 +K KK K + + +E +E+++K K K K K+K K+ EK ++ ++ + +EE Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59 Score = 36.6 bits (83), Expect = 0.11 Identities = 14/48 (29%), Positives = 33/48 (68%) Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKS 894 E ++E+ ++ ++K + +KE R+++KKKK R+ + + ++K K+ K+ Sbjct: 73 EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120 Score = 35.8 bits (81), Expect = 0.19 Identities = 19/82 (23%), Positives = 40/82 (48%), Gaps = 6/82 (7%) Query: 850 QKEKHKKNKDKHKAK------KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSS 903 +KEK KK K+ K K K+ +RK++KKK+ + + + +++ ++ E+ E Sbjct: 39 EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK 98 Query: 904 DSQSDEETADVSPQELLRRLKS 925 + + ++ RR K+ Sbjct: 99 KKKKRRRKEEEEEKKKKRRRKT 120 Score = 35.4 bits (80), Expect = 0.25 Identities = 15/41 (36%), Positives = 28/41 (68%) Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQK 887 E ++E+ K+ + K KK+ RRK+E+++K +K + K K+K Sbjct: 83 EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 Score = 32.7 bits (73), Expect = 1.6 Identities = 15/60 (25%), Positives = 35/60 (58%), Gaps = 4/60 (6%) Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKE----KKKKHRKHKHKGKQKNKKPEKSSSSE 898 R+ + ++E+ ++ +++ + +KE K+E KKKK R+ K + ++K KK + + + Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 52.8 bits (125), Expect = 2e-06 Identities = 52/255 (20%), Positives = 107/255 (41%), Gaps = 27/255 (10%) Query: 657 ASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARS-KAEPPKQQSS 715 A+ T + + E S + P K R+ + + KE S ++ L + + + K+Q + Sbjct: 1513 ATYDTKRPNEETKSVDKNPCKDREKHVLEARNN--KESSGNKLLYILNPPETQVEKEQIT 1570 Query: 716 PLVNKEE-EHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQG 774 ++K + P+LS + ++ D+ + + P + S S+ S E+E Sbjct: 1571 GQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYN------ESDSESNVSVKEEESS 1624 Query: 775 -----DSEDDQAGSGEANFQSSQDTDLGETSSVAHA---LVPAPQEPPPSFPIQKMQIDE 826 D +D + + ++ +G + + +H+ + P+ P + Sbjct: 1625 GNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSG--------SQ 1676 Query: 827 REEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQ 886 ++++ + +K+KHKK+K KHK K+H + + +K +KHKHK K+ Sbjct: 1677 TRSHSSSASSAESQDSKKKKKKKEKKKHKKHK-KHKKHKKHAGTEVELEKSQKHKHKKKK 1735 Query: 887 KNKKPEKSSSSESSD 901 K +K E D Sbjct: 1736 SKKNKDKEKEKEKDD 1750 Score = 36.6 bits (83), Expect = 0.11 Identities = 56/256 (21%), Positives = 99/256 (38%), Gaps = 28/256 (10%) Query: 676 DKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735 + SRK SR T E K DS+ F+ +R A P + + + E S ++ Sbjct: 921 ETSRK-SREPTGVEENKTDSL--FVLPSRDDATPVRDEPM-----DAESITFKSVSEKDK 972 Query: 736 KDVDA-QAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDT 794 ++ D +A+G+ ++ D A+ + K + E+ D E +++ E + +++ Sbjct: 973 RERDKPKAKGDKTKRKND-GSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEE 1031 Query: 795 DLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854 P S QK DE+ PR Q + ++EK Sbjct: 1032 ------------TPKTDNTKSSSSSQK---DEKITGTPRKAHSKSAKEHQETKPVKEEKV 1076 Query: 855 KKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADV 914 KK+ K ++ K+EK KK + K K + K EK D + + + Sbjct: 1077 KKDYSKDVKSEKLTTKEEKAKKPNE---KNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI 1133 Query: 915 SPQELLRRLKSLPLRR 930 S E+ +K P R+ Sbjct: 1134 SKLEVTEIVKPSPKRK 1149 Score = 35.4 bits (80), Expect = 0.25 Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 14/167 (8%) Query: 663 QASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEE 722 +A S+ +H+ KP + + K + +D SE L+ KA+ P +++ PL NK E Sbjct: 1056 KAHSKSAKEHQ----ETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1111 Query: 723 EHAPELSANQTVNKDVDAQAEGEGSRPS-MDLFRAIFASSSDEKSSSSEDEQGDSEDDQ- 780 + +T K VD E + S +++ + S + +E E D+ Sbjct: 1112 KR-----KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI 1166 Query: 781 ---AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQI 824 A + + +G T ++++ P+ + S +++ ++ Sbjct: 1167 SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKV 1213 Score = 34.7 bits (78), Expect = 0.42 Identities = 71/344 (20%), Positives = 125/344 (36%), Gaps = 55/344 (15%) Query: 558 YASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDK 617 Y S+ ST S ++E+ D+ + + +E + + A + + ++ + +W D Sbjct: 1234 YTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQS--KWDKDD 1291 Query: 618 LLCKRFNVPDPYPDSTLVGLPR--VKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGP 675 + +V P S+ VG P +K N + PE S P SEK+ Sbjct: 1292 FESEEEDVKSTQPISS-VGKPASVIKNVSTKPSNIVKYPEKESEP-----SEKIQ----- 1340 Query: 676 DKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735 K K + +HE K S A S+ K + ++ KE + S Sbjct: 1341 -KFTKDVSHEIIQHEVKSSKNS-----ASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKE 1394 Query: 736 KDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTD 795 ++D E +G+ F+++ SS + ++S D S + N D D Sbjct: 1395 SNLDRLNE-QGN------FKSLSQSSKEARTSDKHDSTRASSNKDF---TPNRDKKTDYD 1444 Query: 796 LGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHK 855 E SS + DE+ E R P+ + QK K + Sbjct: 1445 TREYSS-------------------SKRRDEKNELTRRKDS---PSRNKDSASGQKNKPR 1482 Query: 856 KNKD-KHKAKKEHRRKKEKKKKHRK-HKHKGKQKNKKPEKSSSS 897 + +D K + ++ + RK H HK K+P + + S Sbjct: 1483 EERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1526 Score = 30.4 bits (67), Expect = 8.0 Identities = 39/239 (16%), Positives = 88/239 (36%), Gaps = 20/239 (8%) Query: 682 SRWDTSKHEKKEDSI--SEFLSLARSKAEPPKQQS---SPLVNKEEEHAPELSANQTVNK 736 S+WD E +E+ + ++ +S A K S S +V E+ + Q K Sbjct: 1285 SKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTK 1344 Query: 737 DVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDL 796 DV + + S + S+S EK + + + E + + + Q ++++L Sbjct: 1345 DVSHEIIQHEVKSSKN-------SASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNL 1397 Query: 797 GETSSVAH--ALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854 + + +L + +E S + ++F P + + + + Sbjct: 1398 DRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNR------DKKTDYDTREYSSS 1451 Query: 855 KKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETAD 913 K+ +K++ + K K+K +++ P+K + +S D + D Sbjct: 1452 KRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHD 1510 >gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens] Length = 1792 Score = 52.8 bits (125), Expect = 2e-06 Identities = 52/255 (20%), Positives = 107/255 (41%), Gaps = 27/255 (10%) Query: 657 ASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARS-KAEPPKQQSS 715 A+ T + + E S + P K R+ + + KE S ++ L + + + K+Q + Sbjct: 1547 ATYDTKRPNEETKSVDKNPCKDREKHVLEARNN--KESSGNKLLYILNPPETQVEKEQIT 1604 Query: 716 PLVNKEE-EHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQG 774 ++K + P+LS + ++ D+ + + P + S S+ S E+E Sbjct: 1605 GQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYN------ESDSESNVSVKEEESS 1658 Query: 775 -----DSEDDQAGSGEANFQSSQDTDLGETSSVAHA---LVPAPQEPPPSFPIQKMQIDE 826 D +D + + ++ +G + + +H+ + P+ P + Sbjct: 1659 GNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSG--------SQ 1710 Query: 827 REEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQ 886 ++++ + +K+KHKK+K KHK K+H + + +K +KHKHK K+ Sbjct: 1711 TRSHSSSASSAESQDSKKKKKKKEKKKHKKHK-KHKKHKKHAGTEVELEKSQKHKHKKKK 1769 Query: 887 KNKKPEKSSSSESSD 901 K +K E D Sbjct: 1770 SKKNKDKEKEKEKDD 1784 Score = 36.6 bits (83), Expect = 0.11 Identities = 56/256 (21%), Positives = 99/256 (38%), Gaps = 28/256 (10%) Query: 676 DKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735 + SRK SR T E K DS+ F+ +R A P + + + E S ++ Sbjct: 955 ETSRK-SREPTGVEENKTDSL--FVLPSRDDATPVRDEPM-----DAESITFKSVSEKDK 1006 Query: 736 KDVDA-QAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDT 794 ++ D +A+G+ ++ D A+ + K + E+ D E +++ E + +++ Sbjct: 1007 RERDKPKAKGDKTKRKND-GSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEE 1065 Query: 795 DLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854 P S QK DE+ PR Q + ++EK Sbjct: 1066 ------------TPKTDNTKSSSSSQK---DEKITGTPRKAHSKSAKEHQETKPVKEEKV 1110 Query: 855 KKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADV 914 KK+ K ++ K+EK KK + K K + K EK D + + + Sbjct: 1111 KKDYSKDVKSEKLTTKEEKAKKPNE---KNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI 1167 Query: 915 SPQELLRRLKSLPLRR 930 S E+ +K P R+ Sbjct: 1168 SKLEVTEIVKPSPKRK 1183 Score = 35.4 bits (80), Expect = 0.25 Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 14/167 (8%) Query: 663 QASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEE 722 +A S+ +H+ KP + + K + +D SE L+ KA+ P +++ PL NK E Sbjct: 1090 KAHSKSAKEHQ----ETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1145 Query: 723 EHAPELSANQTVNKDVDAQAEGEGSRPS-MDLFRAIFASSSDEKSSSSEDEQGDSEDDQ- 780 + +T K VD E + S +++ + S + +E E D+ Sbjct: 1146 KR-----KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI 1200 Query: 781 ---AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQI 824 A + + +G T ++++ P+ + S +++ ++ Sbjct: 1201 SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKV 1247 Score = 34.7 bits (78), Expect = 0.42 Identities = 71/344 (20%), Positives = 125/344 (36%), Gaps = 55/344 (15%) Query: 558 YASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDK 617 Y S+ ST S ++E+ D+ + + +E + + A + + ++ + +W D Sbjct: 1268 YTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQS--KWDKDD 1325 Query: 618 LLCKRFNVPDPYPDSTLVGLPR--VKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGP 675 + +V P S+ VG P +K N + PE S P SEK+ Sbjct: 1326 FESEEEDVKSTQPISS-VGKPASVIKNVSTKPSNIVKYPEKESEP-----SEKIQ----- 1374 Query: 676 DKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735 K K + +HE K S A S+ K + ++ KE + S Sbjct: 1375 -KFTKDVSHEIIQHEVKSSKNS-----ASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKE 1428 Query: 736 KDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTD 795 ++D E +G+ F+++ SS + ++S D S + N D D Sbjct: 1429 SNLDRLNE-QGN------FKSLSQSSKEARTSDKHDSTRASSNKDF---TPNRDKKTDYD 1478 Query: 796 LGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHK 855 E SS + DE+ E R P+ + QK K + Sbjct: 1479 TREYSS-------------------SKRRDEKNELTRRKDS---PSRNKDSASGQKNKPR 1516 Query: 856 KNKD-KHKAKKEHRRKKEKKKKHRK-HKHKGKQKNKKPEKSSSS 897 + +D K + ++ + RK H HK K+P + + S Sbjct: 1517 EERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1560 Score = 30.4 bits (67), Expect = 8.0 Identities = 39/239 (16%), Positives = 88/239 (36%), Gaps = 20/239 (8%) Query: 682 SRWDTSKHEKKEDSI--SEFLSLARSKAEPPKQQS---SPLVNKEEEHAPELSANQTVNK 736 S+WD E +E+ + ++ +S A K S S +V E+ + Q K Sbjct: 1319 SKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTK 1378 Query: 737 DVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDL 796 DV + + S + S+S EK + + + E + + + Q ++++L Sbjct: 1379 DVSHEIIQHEVKSSKN-------SASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNL 1431 Query: 797 GETSSVAH--ALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854 + + +L + +E S + ++F P + + + + Sbjct: 1432 DRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNR------DKKTDYDTREYSSS 1485 Query: 855 KKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETAD 913 K+ +K++ + K K+K +++ P+K + +S D + D Sbjct: 1486 KRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHD 1544 >gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] Length = 170 Score = 52.0 bits (123), Expect = 3e-06 Identities = 24/52 (46%), Positives = 34/52 (65%) Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 +K+K KK K K K KK+ ++KK+KKKK RK K K K+K KK K ++ + Sbjct: 113 KKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164 Score = 52.0 bits (123), Expect = 3e-06 Identities = 23/51 (45%), Positives = 36/51 (70%) Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS 900 +K+K KK K K K KK+ ++KK+K+K+ RK K K K+K KK +K + +E + Sbjct: 117 KKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGA 167 Score = 51.6 bits (122), Expect = 3e-06 Identities = 24/64 (37%), Positives = 38/64 (59%) Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS 902 R+ + +KEK KK K K K KK+ ++KK+KKKK +K K K K+K K+ K + Sbjct: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161 Query: 903 SDSQ 906 + ++ Sbjct: 162 TGNE 165 Score = 51.2 bits (121), Expect = 4e-06 Identities = 25/50 (50%), Positives = 33/50 (66%) Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK 893 Q E +KEK KK K K K KK+ ++KK+KKKK +K K K K+K K+ K Sbjct: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150 Score = 50.4 bits (119), Expect = 7e-06 Identities = 24/65 (36%), Positives = 37/65 (56%) Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDE 909 +KEK K+ K K K KK+ ++KK+KKKK +K K K K+K K+ K + ++ Sbjct: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164 Query: 910 ETADV 914 E A + Sbjct: 165 EGAKI 169 Score = 48.5 bits (114), Expect = 3e-05 Identities = 23/46 (50%), Positives = 35/46 (76%), Gaps = 1/46 (2%) Query: 848 VPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK 893 +PQ+E+ KK K+K K KK+ ++KK+KKKK +K K K K+K KK ++ Sbjct: 99 LPQREE-KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKR 143 Score = 43.1 bits (100), Expect = 0.001 Identities = 22/56 (39%), Positives = 36/56 (64%), Gaps = 1/56 (1%) Query: 838 FCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK 893 FC +A +L +P ++ + K K K++ ++KK+KKKK +K K K K+K KK +K Sbjct: 85 FC-DAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKK 139 >gi|56090620 NFKB activating protein-like [Homo sapiens] Length = 402 Score = 52.0 bits (123), Expect = 3e-06 Identities = 57/232 (24%), Positives = 87/232 (37%), Gaps = 27/232 (11%) Query: 687 SKHEKKEDSISEFLSLARSKAEPPKQQS--SPLVNKEEEHAPELSANQTVNKDVDAQA-- 742 S+ ED + S PP QS S H+ + ++D A Sbjct: 5 SRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALY 64 Query: 743 --EGEGSRPSMDLFRAI-FASS-SDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGE 798 GSR + FR FASS S S +E+ Q+ +S + L E Sbjct: 65 PFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKE 124 Query: 799 TSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNK 858 + P P P FP Q+D E +E ++ H+K+ Sbjct: 125 RERIGELGAPEVWGPSPKFP----QLDSDEH--------------TPVEDEEEVTHQKSS 166 Query: 859 DKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910 +EHR+KK + +++K K K K +K K S S+S+ SD+ SD + Sbjct: 167 SSDSNSEEHRKKKTSRSRNKK-KRKNKSSKRKHRKYSDSDSNSESDTNSDSD 217 >gi|168229156 NFKB activating protein [Homo sapiens] Length = 415 Score = 51.6 bits (122), Expect = 3e-06 Identities = 30/83 (36%), Positives = 40/83 (48%), Gaps = 23/83 (27%) Query: 851 KEKHKKNKDKHKAKKEH-----------------------RRKKEKKKKHRKHKHKGKQK 887 KE+ KK + K +K++H RR K+ KKK +K KH+ K+ Sbjct: 190 KERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKY 249 Query: 888 NKKPEKSSSSESSDSSDSQSDEE 910 KK K S ESSDSS +S EE Sbjct: 250 KKKRSKKSRKESSDSSSKESQEE 272 Score = 43.5 bits (101), Expect = 0.001 Identities = 19/64 (29%), Positives = 33/64 (51%) Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDE 909 + E+ KK+ +E ++KK + K R K + K+ +K+ K S +S SDS++D Sbjct: 164 EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223 Query: 910 ETAD 913 D Sbjct: 224 SDED 227 Score = 43.5 bits (101), Expect = 0.001 Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQ 906 E P+K + + + KK+ R KE+ KK RK K K+K+KK + S S+S +DS Sbjct: 166 EEPKKSTTSASTSEEEKKKKSSRSKERSKKRRK-KKSSKRKHKKYSEDSDSDSDSETDS- 223 Query: 907 SDEE 910 SDE+ Sbjct: 224 SDED 227 Score = 39.7 bits (91), Expect = 0.013 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 6/89 (6%) Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS 902 + T E+ KK K ++ + R KK +KKK K KHK K + S S +DS Sbjct: 170 KSTTSASTSEEEKKKKS---SRSKERSKKRRKKKSSKRKHK---KYSEDSDSDSDSETDS 223 Query: 903 SDSQSDEETADVSPQELLRRLKSLPLRRQ 931 SD + +E ++ +S +++ Sbjct: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKK 252 Score = 33.5 bits (75), Expect = 0.95 Identities = 49/241 (20%), Positives = 86/241 (35%), Gaps = 50/241 (20%) Query: 664 ASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEE 723 +SS + P S KP W + +++E+S+ R K +++ L Sbjct: 96 SSSVYYGSYSRPYGSDKP--WPSLLDKEREESL-------RQKRLSERERIGEL------ 140 Query: 724 HAPELSANQTVNK--DVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQA 781 APE+ N D D E P A + +K SS E+ + Sbjct: 141 GAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKK 200 Query: 782 GSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPN 841 S + + S+D+D S + D +E N Sbjct: 201 SSKRKHKKYSEDSDSDSDS----------------------ETDSSDE----------DN 228 Query: 842 ARQTLEVPQKEKHKKNKDK-HKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS 900 R+ + +KEK KK++ K +K K+ + +KE K + +N +++ + E S Sbjct: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPS 288 Query: 901 D 901 D Sbjct: 289 D 289 >gi|48255931 hepatoma-derived growth factor-related protein 2 isoform 1 [Homo sapiens] Length = 671 Score = 51.6 bits (122), Expect = 3e-06 Identities = 51/250 (20%), Positives = 104/250 (41%), Gaps = 19/250 (7%) Query: 662 TQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKE 721 + + S+K S + G + + SK +K S + S++ S+ E + S + Sbjct: 142 SDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSD 201 Query: 722 EEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQA 781 ++ PE K +A G +A AS SD K+ S + ++ Sbjct: 202 QDFTPE--------KKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARS 253 Query: 782 GSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPN 841 S ++ SS D+D+ P P P+ K + + + P PP + Sbjct: 254 ASSSSSSSSSSDSDVSVKK-------PPRGRKPAEKPLPKPRGRKPK---PERPPSSSSS 303 Query: 842 ARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGK-QKNKKPEKSSSSESS 900 + EV + + K+ + + + E RR++E++++ R+ + + K +K ++ E++ E+ Sbjct: 304 DSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAE 363 Query: 901 DSSDSQSDEE 910 S S +E Sbjct: 364 RGSGGSSGDE 373 Score = 33.5 bits (75), Expect = 0.95 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 9/100 (9%) Query: 694 DSISEFLSLARSKAEPPKQQSSPLVNK---EEEHAPELSANQTVNKDVDAQAEGEGSRPS 750 + +E + +S+ PK ++ VNK E+E A E A + + + Q + E +PS Sbjct: 537 EKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAE-DKPS 595 Query: 751 MDLFRAIFASSSDEKSSSSED---EQG-DSED-DQAGSGE 785 DL + ++ +K S+ED E+G DSE+ + GS E Sbjct: 596 TDLSAPVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSE 635 Score = 33.1 bits (74), Expect = 1.2 Identities = 68/330 (20%), Positives = 108/330 (32%), Gaps = 50/330 (15%) Query: 631 DSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHE 690 D G + +KY +F F T ETA L + + DK KP+ K + Sbjct: 26 DDIADGAVKPPPNKYPIFFFGT-HETAFL----GPKDLFPYDKCKDKYGKPN-----KRK 75 Query: 691 KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPS 750 + + E + + P P V+ + APE AN D D E G Sbjct: 76 GFNEGLWEIQNNPHASYSAP-----PPVSSSDSEAPE--ANPADGSDADEDDEDRG---- 124 Query: 751 MDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAP 810 + A+ A+++ ++ S D S++ + S + SS +P Sbjct: 125 VMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSP 184 Query: 811 QEPPPSFPIQKMQIDEREEFGP------RLPPVFCPNARQTLEVPQKEKHKKNKDKHKAK 864 E S + + ++F P R P R+ + P D AK Sbjct: 185 SEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAK 244 Query: 865 KEH-----------------------RRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 E ++ +K K K + + KPE+ SS SSD Sbjct: 245 PEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSD 304 Query: 902 SSDSQSDEETADVSPQELLRRLKSLPLRRQ 931 S + D + E RR RR+ Sbjct: 305 SDSDEVDRISEWKRRDEARRRELEARRRRE 334 >gi|14249158 hepatoma-derived growth factor-related protein 2 isoform 2 [Homo sapiens] Length = 670 Score = 51.6 bits (122), Expect = 3e-06 Identities = 51/250 (20%), Positives = 104/250 (41%), Gaps = 19/250 (7%) Query: 662 TQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKE 721 + + S+K S + G + + SK +K S + S++ S+ E + S + Sbjct: 142 SDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSD 201 Query: 722 EEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQA 781 ++ PE K +A G +A AS SD K+ S + ++ Sbjct: 202 QDFTPE--------KKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARS 253 Query: 782 GSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPN 841 S ++ SS D+D+ P P P+ K + + + P PP + Sbjct: 254 ASSSSSSSSSSDSDVSVKK-------PPRGRKPAEKPLPKPRGRKPK---PERPPSSSSS 303 Query: 842 ARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGK-QKNKKPEKSSSSESS 900 + EV + + K+ + + + E RR++E++++ R+ + + K +K ++ E++ E+ Sbjct: 304 DSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAE 363 Query: 901 DSSDSQSDEE 910 S S +E Sbjct: 364 RGSGGSSGDE 373 Score = 34.7 bits (78), Expect = 0.42 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 9/116 (7%) Query: 694 DSISEFLSLARSKAEPPKQQSSPLVNK---EEEHAPELSANQTVNKDVDAQAEGEGSRPS 750 + +E + +S+ PK ++ VNK E+E A E A + + + Q + E +PS Sbjct: 537 EKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAE-DKPS 595 Query: 751 MDLFRAIFASSSDEKSSSSED---EQG-DSED-DQAGSGEANFQSSQDTDLGETSS 801 DL + ++ +K S+ED E+G DSE+ + GS E + DL S Sbjct: 596 TDLSAPVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDLHDVREGPDLDRPGS 651 Score = 33.1 bits (74), Expect = 1.2 Identities = 68/330 (20%), Positives = 108/330 (32%), Gaps = 50/330 (15%) Query: 631 DSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHE 690 D G + +KY +F F T ETA L + + DK KP+ K + Sbjct: 26 DDIADGAVKPPPNKYPIFFFGT-HETAFL----GPKDLFPYDKCKDKYGKPN-----KRK 75 Query: 691 KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPS 750 + + E + + P P V+ + APE AN D D E G Sbjct: 76 GFNEGLWEIQNNPHASYSAP-----PPVSSSDSEAPE--ANPADGSDADEDDEDRG---- 124 Query: 751 MDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAP 810 + A+ A+++ ++ S D S++ + S + SS +P Sbjct: 125 VMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSP 184 Query: 811 QEPPPSFPIQKMQIDEREEFGP------RLPPVFCPNARQTLEVPQKEKHKKNKDKHKAK 864 E S + + ++F P R P R+ + P D AK Sbjct: 185 SEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAK 244 Query: 865 KEH-----------------------RRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 E ++ +K K K + + KPE+ SS SSD Sbjct: 245 PEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSD 304 Query: 902 SSDSQSDEETADVSPQELLRRLKSLPLRRQ 931 S + D + E RR RR+ Sbjct: 305 SDSDEVDRISEWKRRDEARRRELEARRRRE 334 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 51.2 bits (121), Expect = 4e-06 Identities = 59/261 (22%), Positives = 114/261 (43%), Gaps = 41/261 (15%) Query: 684 WDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAE 743 WD S EK+ + + LAR + + + ++NKEE+ E S + +V E Sbjct: 2123 WDFS--EKRSELTKDEKKLARKQRKLANKMRR-MINKEEKMTEEESKLARKHSEVILDDE 2179 Query: 744 GEGSRPSMDLFRAI---FASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETS 800 EG ++ + + + K E+ S+ D+ S E +F ++ L E Sbjct: 2180 EEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVES-EEHFSEEMESLLDELE 2238 Query: 801 SVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKD- 859 QE + + +EREE R+ EV ++E+ +K ++ Sbjct: 2239 K---------QES-----LSSEEEEEREE----------EEEREEEEVREEEEERKEEEE 2274 Query: 860 ---KHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS-SDSQSDEETADVS 915 K K+E +KK+KK+K ++ + ++ ++ E+ S E ++S SD + +EE+ + Sbjct: 2275 GEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334 Query: 916 PQ-----ELLRRLKSLPLRRQ 931 + E+L++ K L+ Q Sbjct: 2335 EEVDREKEILKKEKQFKLQEQ 2355 >gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] Length = 2039 Score = 51.2 bits (121), Expect = 4e-06 Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 27/362 (7%) Query: 573 KEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDS 632 ++E D ++ E + + +K+S +K K K+ R TFE K+ + + D S Sbjct: 780 EKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFE-KEKKIKHEHKSEKDKLDLS 838 Query: 633 TLVGLPRVKRDKYSVFNFLTLPE------TASLPTT---QASSEKVSQHRGPDKSRKPSR 683 V + K YS E TA++ T + S EK+ + +K K Sbjct: 839 ECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH 898 Query: 684 WDTSKHE---KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDA 740 SK + +K++ S+ ++S+ K++ L KE+ E S N T +K + Sbjct: 899 LAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE-SINITNSKHIQE 957 Query: 741 QAEG---EGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLG 797 + + +G++ + ++ + DE + + ++ D +D + + + D Sbjct: 958 EKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYK---ERDKHKDKI 1014 Query: 798 ETSSVAHALVPAPQEPPPSFPIQK-MQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKK 856 + +S+ A + P S P K + E+ L ++ ++ HKK Sbjct: 1015 QINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKK 1074 Query: 857 NKDKHKAKKEHRRKKE-----KKKKHRKHKHKGKQ-KNKKPEKSSSSESSDSSDSQSDEE 910 +K+K K K++ R + K K K KH + KNK+ +S SSE +D+ + + Sbjct: 1075 HKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPK 1134 Query: 911 TA 912 A Sbjct: 1135 DA 1136 Score = 35.4 bits (80), Expect = 0.25 Identities = 40/184 (21%), Positives = 78/184 (42%), Gaps = 27/184 (14%) Query: 741 QAEGEGSRP-------SMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQD 793 QA G RP ++L SD+ S ++ E+ S + + + ++ +D Sbjct: 256 QANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKD 315 Query: 794 TDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEK 853 + + E+ + + P P + + + D+ EE + + +KE+ Sbjct: 316 SLICESKQILPSKTPLPS----ALDEYEFKDDDDEEINKMI---------DDRHILRKEQ 362 Query: 854 HKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK--SSSSESSDSSDSQSDEET 911 K+N+ + A+K H K++K + K K K +KP + SS+ESSD Q+ + + Sbjct: 363 RKENEPE--AEKTHLFAKQEKAFYPK---SFKSKKQKPSRVLYSSTESSDEEALQNKKIS 417 Query: 912 ADVS 915 S Sbjct: 418 TSCS 421 Score = 32.3 bits (72), Expect = 2.1 Identities = 62/276 (22%), Positives = 101/276 (36%), Gaps = 34/276 (12%) Query: 654 PETASLPTTQASSEKVSQHRGPDKSRK--PSRWDTSKHEKKEDSISEFLSLARSKAEPPK 711 P +T++S E+ Q++ S P ++ KKE +S K Sbjct: 395 PSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLK 454 Query: 712 QQSSPLVN---KEEEHAPELS--ANQTVNKDVDA----QAEGEGSRP-------SMDLFR 755 Q+ N K+E+ E + N TVN +D + EG + S+ LF Sbjct: 455 NQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFH 514 Query: 756 AIFASSSDEKSSSSEDEQGDSEDDQA------GSGEANFQ-------SSQDTDLGETSSV 802 S SE + + + GS E + Q +++ L E+SSV Sbjct: 515 ISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSV 574 Query: 803 AHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHK 862 + F ++ + + P F N+ TL+ + +K K KHK Sbjct: 575 KSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTF-ENSDCTLK--KMDKEGKTLKKHK 631 Query: 863 AKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSE 898 K + R K++ KK+ K K K K+ E S E Sbjct: 632 LKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVE 667 >gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] Length = 2062 Score = 51.2 bits (121), Expect = 4e-06 Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 27/362 (7%) Query: 573 KEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDS 632 ++E D ++ E + + +K+S +K K K+ R TFE K+ + + D S Sbjct: 803 EKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFE-KEKKIKHEHKSEKDKLDLS 861 Query: 633 TLVGLPRVKRDKYSVFNFLTLPE------TASLPTT---QASSEKVSQHRGPDKSRKPSR 683 V + K YS E TA++ T + S EK+ + +K K Sbjct: 862 ECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH 921 Query: 684 WDTSKHE---KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDA 740 SK + +K++ S+ ++S+ K++ L KE+ E S N T +K + Sbjct: 922 LAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE-SINITNSKHIQE 980 Query: 741 QAEG---EGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLG 797 + + +G++ + ++ + DE + + ++ D +D + + + D Sbjct: 981 EKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYK---ERDKHKDKI 1037 Query: 798 ETSSVAHALVPAPQEPPPSFPIQK-MQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKK 856 + +S+ A + P S P K + E+ L ++ ++ HKK Sbjct: 1038 QINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKK 1097 Query: 857 NKDKHKAKKEHRRKKE-----KKKKHRKHKHKGKQ-KNKKPEKSSSSESSDSSDSQSDEE 910 +K+K K K++ R + K K K KH + KNK+ +S SSE +D+ + + Sbjct: 1098 HKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPK 1157 Query: 911 TA 912 A Sbjct: 1158 DA 1159 Score = 35.4 bits (80), Expect = 0.25 Identities = 40/184 (21%), Positives = 78/184 (42%), Gaps = 27/184 (14%) Query: 741 QAEGEGSRP-------SMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQD 793 QA G RP ++L SD+ S ++ E+ S + + + ++ +D Sbjct: 279 QANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKD 338 Query: 794 TDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEK 853 + + E+ + + P P + + + D+ EE + + +KE+ Sbjct: 339 SLICESKQILPSKTPLPS----ALDEYEFKDDDDEEINKMI---------DDRHILRKEQ 385 Query: 854 HKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK--SSSSESSDSSDSQSDEET 911 K+N+ + A+K H K++K + K K K +KP + SS+ESSD Q+ + + Sbjct: 386 RKENEPE--AEKTHLFAKQEKAFYPK---SFKSKKQKPSRVLYSSTESSDEEALQNKKIS 440 Query: 912 ADVS 915 S Sbjct: 441 TSCS 444 Score = 32.3 bits (72), Expect = 2.1 Identities = 62/276 (22%), Positives = 101/276 (36%), Gaps = 34/276 (12%) Query: 654 PETASLPTTQASSEKVSQHRGPDKSRK--PSRWDTSKHEKKEDSISEFLSLARSKAEPPK 711 P +T++S E+ Q++ S P ++ KKE +S K Sbjct: 418 PSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLK 477 Query: 712 QQSSPLVN---KEEEHAPELS--ANQTVNKDVDA----QAEGEGSRP-------SMDLFR 755 Q+ N K+E+ E + N TVN +D + EG + S+ LF Sbjct: 478 NQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFH 537 Query: 756 AIFASSSDEKSSSSEDEQGDSEDDQA------GSGEANFQ-------SSQDTDLGETSSV 802 S SE + + + GS E + Q +++ L E+SSV Sbjct: 538 ISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSV 597 Query: 803 AHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHK 862 + F ++ + + P F N+ TL+ + +K K KHK Sbjct: 598 KSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTF-ENSDCTLK--KMDKEGKTLKKHK 654 Query: 863 AKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSE 898 K + R K++ KK+ K K K K+ E S E Sbjct: 655 LKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVE 690 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 50.8 bits (120), Expect = 6e-06 Identities = 51/244 (20%), Positives = 92/244 (37%), Gaps = 17/244 (6%) Query: 675 PDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTV 734 P+K++ P + + EK + + E + ++ SP+ KEEE E+ + Sbjct: 782 PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV--KEEEKPQEVKVKEPP 839 Query: 735 NKDVDAQAEGEG-SRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQD 793 K + +A + D + K E ++ E + EA + ++D Sbjct: 840 KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED 899 Query: 794 ---TDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQ 850 E + A V +P + K + D+ + P P E + Sbjct: 900 KKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA----------EKKE 949 Query: 851 KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNK-KPEKSSSSESSDSSDSQSDE 909 KK+ + KAKK + K + K K K+ +K K EK+ S S+D DS+ E Sbjct: 950 AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009 Query: 910 ETAD 913 + + Sbjct: 1010 KATE 1013 Score = 49.7 bits (117), Expect = 1e-05 Identities = 57/265 (21%), Positives = 113/265 (42%), Gaps = 16/265 (6%) Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQS 714 E A+ P +A S + + P +++ P + + +K + S + S A+ +A+ P + Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEK-EEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565 Query: 715 SPLVNKEEEHAP-ELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQ 773 SP KEE +P E+ + + +A+ S + ++ +E S +E + Sbjct: 566 SP--EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS---PVKEEAKSPAEAKS 620 Query: 774 GDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPP-PSFPIQKMQIDEREEFGP 832 E+ ++ + + + ++ E S A P +E P ++ + + Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680 Query: 833 RLPPVFCPNARQTLEVPQKEKHK-----KNKDKHKAKKEHRRK---KEKKKKHRKHKHKG 884 + P + + + P KE+ K K+ K +AK + K KE+ K K K Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740 Query: 885 KQKNKKPEKSSSSESSDSSDSQSDE 909 K++ K PEK+ S E + + D +S E Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPE 765 Score = 46.2 bits (108), Expect = 1e-04 Identities = 59/283 (20%), Positives = 118/283 (41%), Gaps = 28/283 (9%) Query: 654 PETASLPTTQ-------ASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSIS-------EF 699 PE A PT + A S + + + P+K++ P + + EK + + + Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694 Query: 700 LSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFA 759 S + +A+ P++ SP+ KEE +PE A V ++ A+ + P + ++ Sbjct: 695 KSPVKEEAKSPEKAKSPV--KEEAKSPE-KAKSPVKEE--AKTPEKAKSPVKEEAKSPEK 749 Query: 760 SSSDEKSSSSEDEQGDSED---DQAGSGEANFQSSQDTDLGE-TSSVAHALVPAPQEPPP 815 + S EK+ + + + +++ ++A S F + + E S A P ++ Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809 Query: 816 SFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKK 875 + +I ++EE + P + E P+K + +K K +++ KKE+ Sbjct: 810 P----EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865 Query: 876 KHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADVSPQE 918 K K K ++K K+P ES + + E+ V E Sbjct: 866 KKEAPKPKVEEK-KEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907 Score = 45.4 bits (106), Expect = 2e-04 Identities = 64/277 (23%), Positives = 117/277 (42%), Gaps = 27/277 (9%) Query: 655 ETASLPTTQASSEKV-----SQHRGPDKSRKPSRWDT-SKHEKKEDSISEFLSLARSKAE 708 E A P S EK ++ + P+K++ P++ + S E K E S A K+ Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS- 580 Query: 709 PPKQQSSPLVNKEEEHAP-ELSANQTVNKDV--DAQAEGEGSRPSMDLFRAIFASSSDEK 765 P++ SP KEE +P E + + V +A++ E P + ++ S EK Sbjct: 581 -PEKAKSPA--KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637 Query: 766 SSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQID 825 + S E+ S + +A S E + ++ + ++ A A P + P ++ + Sbjct: 638 AKSPTKEEAKSPE-KAKSPEK--EEAKSPEKAKSPVKAEAKSPEKAKSP-------VKAE 687 Query: 826 EREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGK 885 + + P + + + P KE+ K + KE + EK K K + K Sbjct: 688 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747 Query: 886 QKNKKPEKSSSSE-SSDSSDSQSDEET---ADVSPQE 918 +K K PEK+ + + S + + + EE AD P++ Sbjct: 748 EKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK 784 Score = 31.6 bits (70), Expect = 3.6 Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 3/79 (3%) Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSS---SESS 900 +T P +E K+ KE + + K K + K + K PEK+ S E+ Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559 Query: 901 DSSDSQSDEETADVSPQEL 919 +++S E+ SP E+ Sbjct: 560 SPPEAKSPEKEEAKSPAEV 578 >gi|117553580 adaptor-related protein complex 3, delta 1 subunit isoform 2 [Homo sapiens] Length = 1153 Score = 50.4 bits (119), Expect = 7e-06 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 16/208 (7%) Query: 709 PPKQQSSPLVNKEEE--HAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKS 766 P S V EEE H +L ++ K + + +G+ S+ + SDE Sbjct: 716 PGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLP-------TESDEDI 768 Query: 767 SSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDE 826 + ++ +E+ + ++ D D + + P PIQK + E Sbjct: 769 APAQQVDIVTEEMPENALPSD---EDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTE 825 Query: 827 REEFGPRLPPVFCPNARQTLEVPQKEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKH--- 882 + + P+ +++ + +K K K ++K+K K K++ + K KKKKHRK K Sbjct: 826 TSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERT 885 Query: 883 KGKQKNKKPEKSSSSESSDSSDSQSDEE 910 KGK+K+KK S + + + + EE Sbjct: 886 KGKKKSKKQPPGSEEAAGEPVQNGAPEE 913 Score = 46.2 bits (108), Expect = 1e-04 Identities = 36/143 (25%), Positives = 66/143 (46%), Gaps = 15/143 (10%) Query: 791 SQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQID-EREEFGPRLPPVFCPNARQTLEVP 849 +Q D+ +AL + P+ P + + ID ++ P+ +T + P Sbjct: 771 AQQVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSP 830 Query: 850 QKE---------KHKKNKDKHKAK---KEHRRKKEKKK--KHRKHKHKGKQKNKKPEKSS 895 +K+ K KK + KHK K KE +++KEKKK K +K KH+ +++ + K Sbjct: 831 EKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKK 890 Query: 896 SSESSDSSDSQSDEETADVSPQE 918 S + S+ + E + +P+E Sbjct: 891 SKKQPPGSEEAAGEPVQNGAPEE 913 Score = 33.1 bits (74), Expect = 1.2 Identities = 51/238 (21%), Positives = 98/238 (41%), Gaps = 44/238 (18%) Query: 715 SPLVNKEEEHAPE---LSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSED 771 +P+ K ++ P L + +N+ + + +E E RP RA+F + Sbjct: 605 NPVAPKAQKKVPVPEGLDLDAWINEPL-SDSESEDERP-----RAVFHEEEQRRPKHRPS 658 Query: 772 EQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFP----IQKMQIDER 827 E E++ A EA Q + SS P+PQ+ P I +QID Sbjct: 659 EA--DEEELARRREARKQEQANNPFYIKSS------PSPQKRYQDTPGVEHIPVVQIDLS 710 Query: 828 EEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKK-HRKHKHKGKQ 886 ++P + P + Q +++ ++ +H++ +K K +K ++KEK+KK R+H + Sbjct: 711 VPL--KVPGL--PMSDQYVKLEEERRHRQKLEKDKRRK---KRKEKEKKGKRRHSSLPTE 763 Query: 887 KN--------------KKPEKSSSSESSDSSDSQSDEETADVSPQELLRRLKSLPLRR 930 + + PE + S+ D D D+ + L + LP+++ Sbjct: 764 SDEDIAPAQQVDIVTEEMPENALPSD-EDDKDPNDPYRALDIDLDKPLADSEKLPIQK 820 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 50.4 bits (119), Expect = 7e-06 Identities = 57/298 (19%), Positives = 112/298 (37%), Gaps = 54/298 (18%) Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQS 714 ET LP + + +E++ D + D KH + I E S +E Sbjct: 124 ETRKLPGSDSENEELLNGHASDSENE----DVGKHPASDSEIEELQKSPASDSETEDALK 179 Query: 715 SPLVNKEEEHAPELSANQTVNKDV------DAQAEGEGSRPSMDLFRAIFASSSDEKSSS 768 + + E E P A+ + N++ D+++E E +P + S E Sbjct: 180 PQISDSESEEPPRHQASDSENEEPPKPRMSDSESE-ELPKPQV---------SDSESEEP 229 Query: 769 SEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQ------EPPP------- 815 + DSE+++ + S+D + S + +P P+ E PP Sbjct: 230 PRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDS 289 Query: 816 -SFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQK-----EKHKKNK----------- 858 + + K ++ + E GP+ P QK + ++NK Sbjct: 290 ENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSF 349 Query: 859 --DKHKAKKEHRRKKEKKKKHRKHKHKGKQKNK--KPEKSSSSESSDSSDSQSDEETA 912 D H +K+ ++++H+K K + K + EK + +++ SDS+ +E+ + Sbjct: 350 HSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKAS 407 Score = 43.1 bits (100), Expect = 0.001 Identities = 62/289 (21%), Positives = 102/289 (35%), Gaps = 70/289 (24%) Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKE-------DSISEFLSLARSKA 707 E+ LP Q S + S +P R S E +E DS SE Sbjct: 212 ESEELPKPQVSDSE---------SEEPPRHQASDSENEELPKPRISDSESE--------- 253 Query: 708 EPPKQQSSPLVNKE----------EEHAPELSANQTVNKDV------DAQAEGEGSRPSM 751 +PP+ Q+S N+E E P A+ + N+++ D+++EG P Sbjct: 254 DPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGP-- 311 Query: 752 DLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQ 811 AS S+ + +S ++ +S+DD + Q+ S + + Sbjct: 312 -------ASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSD 364 Query: 812 EPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKK 871 QKM DE E+ G ++EK K K + E K Sbjct: 365 SEEEEHKKQKMDSDEDEKEG------------------EEEKVAKRKAAVLSDSEDEEKA 406 Query: 872 EKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSD--EETADVSPQE 918 KK + +KS E + +SDS+ + +E +D +E Sbjct: 407 SAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEE 455 Score = 34.3 bits (77), Expect = 0.55 Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 12/118 (10%) Query: 678 SRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKD 737 S K SR + + D++S+ + K++ + + EEE ELS + KD Sbjct: 407 SAKKSRVVSDADDSDSDAVSD---------KSGKREKTIASDSEEEAGKELSDKKNEEKD 457 Query: 738 VDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTD 795 + ++ E +L IF S DE+ E + ED + GE + ++D+D Sbjct: 458 LFG-SDSESGNEEENLIADIFGESGDEE--EEEFTGFNQEDLEEEKGETQVKEAEDSD 512 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 50.1 bits (118), Expect = 1e-05 Identities = 87/451 (19%), Positives = 176/451 (39%), Gaps = 31/451 (6%) Query: 382 AATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAELLGET-PIQGSATSVLEFLSQ 440 A E+ +++ ++ +A P S H+ SK+++ ET P ++ +V + SQ Sbjct: 139 ATNPESKQIVEEKTKRQNEADKTP-LKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQ 197 Query: 441 KDKERIKEMKQA-TDLKAAQLKARSLAQNAQSSRAQLSPAAAAGHCSWNMALGGGTATLK 499 KDK+ K K+ T+ + + + +++S +S + + + + G + + Sbjct: 198 KDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDE 257 Query: 500 ASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMTEWERGRERDEFARAALLYA 559 + NF + ++ + + L + K +KD + S E E ++ + ++ Sbjct: 258 SINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKK----V 313 Query: 560 SSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLL 619 + + K++ +S E ++ K+ K+K K +DT + +P+ Sbjct: 314 KKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDK-KKDT-KKYPESTD 371 Query: 620 CKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPD--K 677 + + D DS + DK +T +T + SE S+ D K Sbjct: 372 TESGDAKDARNDSRNLKKASKNDDKKKDAKKITF-------STDSESELESKESQKDEKK 424 Query: 678 SRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKD 737 +K S+ D K K ++ ++ A+ + S K+E+ + S KD Sbjct: 425 DKKDSKTDNKKSVKNDEESTD--------ADSEPKGDSKKGKKDEKKGKKDSKKDDKKKD 476 Query: 738 VDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLG 797 AE ++L + S EK S +D + D+ D S +A F S T Sbjct: 477 AKKNAESTEMESDLELKKD--KKHSKEKKGSKKDIKKDARKD-TESTDAEFDESSKTGFK 533 Query: 798 ETSSVAHALVPAPQEPPPSFPIQKMQIDERE 828 ++ + + E P K +IDE + Sbjct: 534 TSTKIKGS--DTESEESLYKPGAKKKIDESD 562 Score = 42.0 bits (97), Expect = 0.003 Identities = 53/268 (19%), Positives = 103/268 (38%), Gaps = 19/268 (7%) Query: 644 KYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLA 703 KY+ + + A + S + + K +K + D K + K+D+ S Sbjct: 279 KYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESG 338 Query: 704 RSKAE--PPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASS 761 SK E K+ L +++ + T + DA+ SR + Sbjct: 339 DSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKK 398 Query: 762 SDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQK 821 +K + S D + + E ++ E + TD SV + + P +K Sbjct: 399 DAKKITFSTDSESELESKESQKDEKKDKKDSKTD--NKKSVKNDEESTDADSEPKGDSKK 456 Query: 822 MQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHK 881 + DE++ + + + +K+ KKN + + + + KK+KK H K K Sbjct: 457 GKKDEKK------------GKKDSKKDDKKKDAKKNAESTEMESDLELKKDKK--HSKEK 502 Query: 882 HKGKQKNKKPEKSSSSESSDSSDSQSDE 909 KG +K+ K + +ES+D+ +S + Sbjct: 503 -KGSKKDIKKDARKDTESTDAEFDESSK 529 Score = 37.4 bits (85), Expect = 0.065 Identities = 53/257 (20%), Positives = 108/257 (42%), Gaps = 47/257 (18%) Query: 677 KSRKPSRWDTSKHEKKE-DSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735 K K ++ DT K+ KK D+ SE A+ ++ K+ V K+++ + V Sbjct: 279 KYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKN----VKKDDK-------KKDVK 327 Query: 736 KDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTD 795 KD ++ G S DE+ + +D++ +DD+ + + S DT+ Sbjct: 328 KDTESTDAESGD-------------SKDERKDTKKDKKKLKKDDKKKDTK-KYPESTDTE 373 Query: 796 LGETSSVAHALVPAPQEPPPSFPIQKM-QIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854 G+ + S ++K + D++++ ++ F ++ LE + +K Sbjct: 374 SGDAKDARN----------DSRNLKKASKNDDKKKDAKKI--TFSTDSESELESKESQKD 421 Query: 855 KKNKDKHKAKKEHRRKKEKKKKH-------RKHKHKGKQKNKKPEKSSSSESSDSSDSQS 907 +K KDK +K ++++ + ++ + KGK+ KK +K S + ++ Sbjct: 422 EK-KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKN 480 Query: 908 DEETADVSPQELLRRLK 924 E T S EL + K Sbjct: 481 AESTEMESDLELKKDKK 497 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 49.7 bits (117), Expect = 1e-05 Identities = 100/487 (20%), Positives = 186/487 (38%), Gaps = 71/487 (14%) Query: 441 KDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAAAAGHCSWNMALGGGTATLKA 500 K++ RI ++ D L++R + Q ++ P +G+ + + T K Sbjct: 175 KERSRINSSGESGDESDEFLQSRKGQKKNQKNKP--GPNIESGNEDDDASFKIKTVAQK- 231 Query: 501 SNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMTEWERGRERDEFARAALLYAS 560 K K+ E++KR +E K +K+ LE + E R+ +E + + Sbjct: 232 ---KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVD 288 Query: 561 SHSTLSSRF---THAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDK 617 + +S T EDD++ + +D++ G+K+ K K G P K Sbjct: 289 TGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKG----------PSK 338 Query: 618 LLCKRFNVPDPYPDSTLVGLP----RVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHR 673 K L L R KR++ L E + EK + + Sbjct: 339 ATVKAMQ-------EALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK 391 Query: 674 GPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSA--N 731 +K RK + K E K + S+ + AR++A Q+ + ++ P+ Sbjct: 392 QKEKERK----ERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYE 447 Query: 732 QTVNKDVDAQAEGEGSRPSMDLFRAI--FASSSDEKSSSSEDEQGDSEDDQAGSGEANFQ 789 K + Q E + SM+L A+ EK + + + E+D +G +++ Sbjct: 448 DKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWE 507 Query: 790 ---SSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTL 846 S ++T+ E + V + P+E +E EE Sbjct: 508 AMASDEETEKVEGNKVHIEVKENPEE------------EEEEE----------------- 538 Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS-DSSDS 905 E ++++ + +++ + + E E+ +K K GK +KKP K SS+S DS D Sbjct: 539 EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDD 598 Query: 906 QSDEETA 912 ++ EE A Sbjct: 599 RTKEERA 605 Score = 42.4 bits (98), Expect = 0.002 Identities = 61/316 (19%), Positives = 123/316 (38%), Gaps = 54/316 (17%) Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSR--WDTSKHEKKEDSISEFLSLARSKAEPPK- 711 ET ++ T+ + E+ + K +K + +D + E+ ED S+ A+ K E Sbjct: 77 ETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSG 136 Query: 712 QQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFAS--SSDEKSSSS 769 NK + A + Q NK D E E + + I +S S DE Sbjct: 137 SDDDDDFNKLPKKAKGKA--QKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFL 194 Query: 770 EDEQGDSEDDQAGSGEANFQSSQDTDLG-ETSSVAHALVPAPQEPPPSFPIQKMQIDERE 828 + +G ++ + G ++D D + +VA + +K ++ + + Sbjct: 195 QSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLK 254 Query: 829 EFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKE---------------------- 866 E ++ LE +K++ K+ + + K ++E Sbjct: 255 E-------------KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAET 301 Query: 867 ----------HRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS-SDSQSDEETADVS 915 ++KK+KKKK + + K K+K K P K++ ++ + + +EE Sbjct: 302 PTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKRE 361 Query: 916 PQELLRRLKSLPLRRQ 931 +E ++RL+ L +R+ Sbjct: 362 EEERIKRLEELEAKRK 377 Score = 36.2 bits (82), Expect = 0.15 Identities = 55/288 (19%), Positives = 113/288 (39%), Gaps = 17/288 (5%) Query: 649 NFLTLPETASLPTTQASSEKVSQHRGPDKSRK-PSRWDTSKHEKKEDSISEFLSLARSKA 707 +F LP+ A +++ + D S+K R + + D EFL + + Sbjct: 142 DFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQK 201 Query: 708 EPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSS 767 + K + P + E +TV + + E E + + + +E + Sbjct: 202 KNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELET 261 Query: 768 SSEDEQGDSEDDQAGSGEANFQSSQDTDLGET-SSVAHALVPAPQEPPPSFPIQKM---- 822 +D Q ++ Q E +S D G +S A P E +K Sbjct: 262 GKKD-QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKK 320 Query: 823 ---QIDEREEFGPRLPPVFCPNARQTL--EVPQKEKHKKNKDKHKAKK----EHRRKKEK 873 + +E+E+ + P A Q ++ ++E+ +K +++ + K+ E +RK+E+ Sbjct: 321 KKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE 380 Query: 874 KKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADVSPQELLR 921 + + K + K KQK K+ ++ E + SQ + + +LL+ Sbjct: 381 RLEQEKRERK-KQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427 Score = 31.2 bits (69), Expect = 4.7 Identities = 60/288 (20%), Positives = 112/288 (38%), Gaps = 63/288 (21%) Query: 670 SQHRGPDKSRKPSRWDTSKHEKKEDSIS---EFLSLARS--KAEPPKQQSSPLVNKEEEH 724 ++ + P KS+ + + K + ED I E LSL KA+ P N EEE Sbjct: 32 AKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEF 91 Query: 725 AP-------ELSANQTVNKDVDAQAEGEGSR------PSMDLFRAIFASSSDE------- 764 + Q+ + + + E + S+ P ++++ S SD+ Sbjct: 92 TSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMY-----SGSDDDDDFNKL 146 Query: 765 ------KSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAP------QE 812 K+ S + SE+D+ S + + S+ GE+ + + + Q+ Sbjct: 147 PKKAKGKAQKSNKKWDGSEEDEDNSKKIK-ERSRINSSGESGDESDEFLQSRKGQKKNQK 205 Query: 813 PPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHK-----KNKDKHKAKKEH 867 P I+ D+ F + V QK+ K K +D+ KAK Sbjct: 206 NKPGPNIESGNEDDDASF-------------KIKTVAQKKAEKKERERKKRDEEKAKLRK 252 Query: 868 RRKKEKKKKHRKHKHKGKQKNKKPEKSS--SSESSDSSDSQSDEETAD 913 ++KE+ + +K + K K+ +K E+ + S + D+ + EE A+ Sbjct: 253 LKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE 300 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 49.3 bits (116), Expect = 2e-05 Identities = 64/297 (21%), Positives = 113/297 (38%), Gaps = 45/297 (15%) Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQ- 713 + A+ PT ++SS + S ++ +KP + + + S+ A PPK+ Sbjct: 255 KAATTPTRKSSSSEDSSSDEEEEQKKPMK----------NKPGPYSSVPPPSAPPPKKSL 304 Query: 714 -SSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEK----SSS 768 + P E+ P + +++ + + D+ +E E P+ + K SSS Sbjct: 305 GTQPPKKAVEKQQP-VESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSS 363 Query: 769 SEDEQGDSEDDQAGSGEANF-QSSQDTDLGETSSVAHALVPAPQEP-----------PPS 816 + SEDD+A S A ++S + T S A AP++P S Sbjct: 364 DSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADS 423 Query: 817 FPIQKMQIDEREEFGPRLPPVFCPNA--RQTLEVPQKE----KHKKNKDKHKAKKEHRRK 870 ++ EE ++ P A + L +P K+ + D + E + Sbjct: 424 SSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEE 483 Query: 871 KEKKKKHRKHKHK----------GKQKNKKPEKSSSSESSDSSDSQSDEETADVSPQ 917 K K +K K K K E S+SS S DSS+ + ++ SP+ Sbjct: 484 KTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPR 540 Score = 47.8 bits (112), Expect = 5e-05 Identities = 68/257 (26%), Positives = 106/257 (41%), Gaps = 36/257 (14%) Query: 678 SRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQ----- 732 S + S D + +KK+ A++ PPK+ S + + E NQ Sbjct: 129 SEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKIT 188 Query: 733 --TVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQS 790 TV A + + P + +A +SSS SSSS+D SE+++A + Sbjct: 189 PVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDD----SEEEKAAA------- 237 Query: 791 SQDTDLGETSSVAHALVPAPQEPP-PSFPIQKMQIDEREEF--------GP--RLPPVFC 839 + + + VA A V A P S + DE EE GP +PP Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSA 297 Query: 840 PNARQTL--EVPQK--EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKP--EK 893 P +++L + P+K EK + + + E E++KK K K P +K Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357 Query: 894 SSSSESSDSSDSQSDEE 910 ++ S SSDSSDS S E+ Sbjct: 358 AAES-SSDSSDSDSSED 373 Score = 47.0 bits (110), Expect = 8e-05 Identities = 53/260 (20%), Positives = 97/260 (37%), Gaps = 39/260 (15%) Query: 660 PTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKED------SISEFLSLARSKAEPPKQQ 713 P + + + P K K S D+ + E I+ A++KA P + Sbjct: 145 PVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPAR 204 Query: 714 SSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQ 773 ++P + + + S++ + + D D++ E + P + + + + K++++ + Sbjct: 205 AAPKIANGKAASSSSSSSSSSSSD-DSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRK 263 Query: 774 GDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQE----PPPSFPIQKMQIDEREE 829 S +D + E + G SSV P P++ PP ++K Q Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQ------ 317 Query: 830 FGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNK 889 PV E + + D+ + E +K K K K K Sbjct: 318 ------PV--------------ESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357 Query: 890 KPEKSSSSESSDSSDSQSDE 909 E SSS+SSDS S+ DE Sbjct: 358 AAE--SSSDSSDSDSSEDDE 375 Score = 37.4 bits (85), Expect = 0.065 Identities = 52/251 (20%), Positives = 88/251 (35%), Gaps = 27/251 (10%) Query: 687 SKHEKKEDSISEFLSLARSKAEPPK---QQSSPLVNKEEEHAPELSANQTVNKDVDAQ-- 741 ++ + S+ + S A+ P+ Q + P+ K ++ A + + ++ + Q Sbjct: 41 TQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGP 100 Query: 742 --------AEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAG------SGEAN 787 A+ G P +A +SSS+E S ++E + Q G + +A Sbjct: 101 PAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAP 160 Query: 788 FQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLE 847 + ++ +D SS P + P P+ + R P N + Sbjct: 161 PKKAKSSDSDSDSSSEDE--PPKNQKPKITPVTVKAQTKAPPKPARAAPKIA-NGKAASS 217 Query: 848 VPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQS 907 + D + K KK KK K K KSSSSE DS S Sbjct: 218 SSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE-----DSSS 272 Query: 908 DEETADVSPQE 918 DEE P + Sbjct: 273 DEEEEQKKPMK 283 >gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] Length = 1303 Score = 49.3 bits (116), Expect = 2e-05 Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHR-KHKHKGKQKNKKPEKSSSSESSDSSDS 905 E +KEK +K+ +K HRR K K+KK R K K + K++ K K +S S D SD Sbjct: 80 ERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDF 139 Query: 906 QSDEETADVSPQE 918 D +D SP E Sbjct: 140 SDD---SDFSPSE 149 >gi|39932583 hypothetical protein LOC55051 isoform 1 [Homo sapiens] Length = 1164 Score = 49.3 bits (116), Expect = 2e-05 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 5/101 (4%) Query: 815 PSFPIQKM-QIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEK 873 PSF + + + ++ E P P R L+ ++ NK K K+ R+KK++ Sbjct: 29 PSFCVGSITSLSQQTEAAPAHVSEGLPLTRSHLKSESSDESDTNK---KLKQTSRKKKKE 85 Query: 874 KKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADV 914 KKK RKH+H K K +K SSSS S +DS+ D+ + V Sbjct: 86 KKKKRKHQHHKKTK-RKHGPSSSSRSETDTDSEKDKPSRGV 125 Score = 35.8 bits (81), Expect = 0.19 Identities = 30/138 (21%), Positives = 54/138 (39%), Gaps = 14/138 (10%) Query: 774 GDSEDDQAGSG--EANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFG 831 G SE GS E ++ S+ +G +S++ AP P+ + + Sbjct: 9 GLSEAPDGGSSRKELDWLSNPSFCVGSITSLSQQTEAAPAHVSEGLPLTRSHLKSESS-- 66 Query: 832 PRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKP 891 + T + ++ KK K+K K K++H+ K+ K+KH + + Sbjct: 67 ---------DESDTNKKLKQTSRKKKKEKKK-KRKHQHHKKTKRKHGPSSSSRSETDTDS 116 Query: 892 EKSSSSESSDSSDSQSDE 909 EK S S +S+E Sbjct: 117 EKDKPSRGVGGSKKESEE 134 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 48.5 bits (114), Expect = 3e-05 Identities = 50/251 (19%), Positives = 89/251 (35%), Gaps = 11/251 (4%) Query: 665 SSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEH 724 S + H +K R S H+K+ S S +RS + ++ + + KE+E Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKER 389 Query: 725 APELSANQTVNKDVDAQAEGE-GSRPSMDLFRAIFASSSDEKSSSSEDEQGDSED-DQAG 782 E + ++ + + E E G D R EK E E+ +D D+ Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449 Query: 783 SGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNA 842 E + + ++ D + + PP S+ + E R + Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR-------RS 502 Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKK-KHRKHKHKGKQKNKKPEKSSSSESSD 901 R + P+ K K K R KK+KK+ K R H + +++ + SS D Sbjct: 503 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 562 Query: 902 SSDSQSDEETA 912 + T+ Sbjct: 563 GKEKLEKNSTS 573 Score = 41.6 bits (96), Expect = 0.003 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 8/75 (10%) Query: 850 QKEKHK-KNKDKHKAK-------KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 +KEK + KNKD+ K + KE R++E++K+H K + K K+K + EK + S Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465 Query: 902 SSDSQSDEETADVSP 916 D + ++ +P Sbjct: 466 EIDEKRKKDKKSRTP 480 Score = 39.7 bits (91), Expect = 0.013 Identities = 30/146 (20%), Positives = 63/146 (43%), Gaps = 6/146 (4%) Query: 766 SSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQID 825 S++ E E G S + + G ++ +S +SS +H+ Q S + + Sbjct: 290 SAAIEPESGKSNERKGGRSRSHTRSKS-----RSSSKSHSRRKRSQSKHRSRSHNRSRSR 344 Query: 826 EREEFGPRLPPVFCPNARQTLEVPQKEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKHKG 884 +++ + P +R+ + + + K KD + KE R KEK ++ + + K Sbjct: 345 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 404 Query: 885 KQKNKKPEKSSSSESSDSSDSQSDEE 910 ++K K+ K+ + D + D+E Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKE 430 Score = 37.7 bits (86), Expect = 0.050 Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 843 RQTLEVPQKEKHKKNKDKHKAK-KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 + T E ++++ K KD+ K + +E R+KEK++ K + K ++K+++ +K E Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437 Query: 902 SSDSQSDEETADVSPQE 918 + + D + Q+ Sbjct: 438 EKEHEKDRDKEKEKEQD 454 Score = 37.0 bits (84), Expect = 0.086 Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 851 KEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDE 909 KE+ K + KDK K +E R+KE +K K K K + K K+ EK S E + Sbjct: 419 KEREKDREKDKEK-DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS 477 Query: 910 ETADVSPQELLRRLKSLPLRRQ 931 T S R S RR+ Sbjct: 478 RTPPRSYNASRRSRSSSRERRR 499 Score = 30.4 bits (67), Expect = 8.0 Identities = 16/72 (22%), Positives = 35/72 (48%) Query: 851 KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910 KEK ++ + + + +K+ ++KEK++ K + K + K ++ +S S + Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 488 Query: 911 TADVSPQELLRR 922 + S +E RR Sbjct: 489 RSRSSSRERRRR 500 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 48.5 bits (114), Expect = 3e-05 Identities = 50/251 (19%), Positives = 89/251 (35%), Gaps = 11/251 (4%) Query: 665 SSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEH 724 S + H +K R S H+K+ S S +RS + ++ + + KE+E Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKER 273 Query: 725 APELSANQTVNKDVDAQAEGE-GSRPSMDLFRAIFASSSDEKSSSSEDEQGDSED-DQAG 782 E + ++ + + E E G D R EK E E+ +D D+ Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333 Query: 783 SGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNA 842 E + + ++ D + + PP S+ + E R + Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR-------RS 386 Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKK-KHRKHKHKGKQKNKKPEKSSSSESSD 901 R + P+ K K K R KK+KK+ K R H + +++ + SS D Sbjct: 387 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 446 Query: 902 SSDSQSDEETA 912 + T+ Sbjct: 447 GKEKLEKNSTS 457 Score = 41.6 bits (96), Expect = 0.003 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 8/75 (10%) Query: 850 QKEKHK-KNKDKHKAK-------KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 +KEK + KNKD+ K + KE R++E++K+H K + K K+K + EK + S Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349 Query: 902 SSDSQSDEETADVSP 916 D + ++ +P Sbjct: 350 EIDEKRKKDKKSRTP 364 Score = 39.7 bits (91), Expect = 0.013 Identities = 30/146 (20%), Positives = 63/146 (43%), Gaps = 6/146 (4%) Query: 766 SSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQID 825 S++ E E G S + + G ++ +S +SS +H+ Q S + + Sbjct: 174 SAAIEPESGKSNERKGGRSRSHTRSKS-----RSSSKSHSRRKRSQSKHRSRSHNRSRSR 228 Query: 826 EREEFGPRLPPVFCPNARQTLEVPQKEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKHKG 884 +++ + P +R+ + + + K KD + KE R KEK ++ + + K Sbjct: 229 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 288 Query: 885 KQKNKKPEKSSSSESSDSSDSQSDEE 910 ++K K+ K+ + D + D+E Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKE 314 Score = 37.7 bits (86), Expect = 0.050 Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 843 RQTLEVPQKEKHKKNKDKHKAK-KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 + T E ++++ K KD+ K + +E R+KEK++ K + K ++K+++ +K E Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321 Query: 902 SSDSQSDEETADVSPQE 918 + + D + Q+ Sbjct: 322 EKEHEKDRDKEKEKEQD 338 Score = 37.0 bits (84), Expect = 0.086 Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 2/82 (2%) Query: 851 KEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDE 909 KE+ K + KDK K +E R+KE +K K K K + K K+ EK S E + Sbjct: 303 KEREKDREKDKEK-DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS 361 Query: 910 ETADVSPQELLRRLKSLPLRRQ 931 T S R S RR+ Sbjct: 362 RTPPRSYNASRRSRSSSRERRR 383 Score = 30.4 bits (67), Expect = 8.0 Identities = 16/72 (22%), Positives = 35/72 (48%) Query: 851 KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910 KEK ++ + + + +K+ ++KEK++ K + K + K ++ +S S + Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 372 Query: 911 TADVSPQELLRR 922 + S +E RR Sbjct: 373 RSRSSSRERRRR 384 >gi|4507347 TBP-associated factor 2 [Homo sapiens] Length = 1199 Score = 48.5 bits (114), Expect = 3e-05 Identities = 56/180 (31%), Positives = 72/180 (40%), Gaps = 18/180 (10%) Query: 742 AEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAG-SGEANFQSSQDT---DLG 797 A S P + F+ F+SS DE+ E + D QA S N T Sbjct: 1021 ANNPSSHPQLVGFQNPFSSSQDEE----EIDMDTVHDSQAFISHHLNMLERPSTPGLSKY 1076 Query: 798 ETSSVAHALVPAPQEPPPSFPIQKMQID---EREEFGPRLPPV---FCPNARQTLEVPQK 851 +S AL+P S P K Q R+ G P+ P A L V K Sbjct: 1077 RPASSRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTK 1136 Query: 852 EKH-KKNKDKHKAKKEHRRKKEKKKKHR---KHKHKGKQKNKKPEKSSSSESSDSSDSQS 907 E K+ D H +KK+KK KH+ KHKH K+K+K+P SS S S S S Sbjct: 1137 ESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPS 1196 >gi|8923271 coiled-coil domain containing 49 [Homo sapiens] Length = 425 Score = 48.1 bits (113), Expect = 4e-05 Identities = 28/75 (37%), Positives = 42/75 (56%), Gaps = 7/75 (9%) Query: 843 RQTLEVPQK-EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 R+ L P K +K K+ KKE ++KKEKKKKH+KHKH+ ++ SS + Sbjct: 151 REVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDR------SSSEDE 204 Query: 902 SSDSQSDEETADVSP 916 S +S ++ A+ SP Sbjct: 205 HSAGRSQKKMANSSP 219 Score = 33.5 bits (75), Expect = 0.95 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 17/124 (13%) Query: 813 PPPSFPIQKMQIDER---EEFGPRLPPVFCPNARQTL--------EVPQKEKHKKNKDKH 861 P + +KM+ E E G +F P+ +L E P KK ++K Sbjct: 91 PIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKK 150 Query: 862 KAKKEHRRKKEKKKK------HRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADVS 915 + + K +K K+ +K K K K+K KK +K SS S DE +A S Sbjct: 151 REVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRS 210 Query: 916 PQEL 919 +++ Sbjct: 211 QKKM 214 >gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapiens] Length = 729 Score = 47.8 bits (112), Expect = 5e-05 Identities = 63/256 (24%), Positives = 98/256 (38%), Gaps = 31/256 (12%) Query: 665 SSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEF-----LSLARSKAEPPKQQSSPLVN 719 SSE+ ++ P K P+ S+ E K SI + R+ A P S Sbjct: 470 SSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTG 529 Query: 720 KEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDD 779 E+ + A K QA S P + + + D+ SE G Sbjct: 530 PEKRSSTRPPAEMEPGKG--EQASSSESDPEGPIAAQMLSFVMDDPDFESE---GSDTQR 584 Query: 780 QAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQI-DEREEFGPRLP--- 835 +A S TD E PA PPP P+ ++ ++ + FG L Sbjct: 585 RADDFPVRDDPSDVTDEDEG--------PAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAG 636 Query: 836 PVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHK--GKQ----KNK 889 P + + P KEK KK K K K+E + +KK KH+K K K GK+ + + Sbjct: 637 PKESSEEGKEGKTPSKEKKKKKK---KGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQ 693 Query: 890 KPEKSSSSESSDSSDS 905 +P +S ++D ++ Sbjct: 694 RPPRSRERTAADELEA 709 >gi|27734775 hypothetical protein LOC286499 [Homo sapiens] Length = 248 Score = 47.4 bits (111), Expect = 6e-05 Identities = 55/240 (22%), Positives = 103/240 (42%), Gaps = 22/240 (9%) Query: 669 VSQHRGPDKSRKPSRWD-------TSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKE 721 +++ RGP +S P+ D T + KK+ + S A ++ E ++ KE Sbjct: 16 MARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENW---KKE 72 Query: 722 EEHAPE--LSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDE-----QG 774 E + E LS N++ +K + E + R + +SSSD SSSS+ E QG Sbjct: 73 LEKSREKLLSGNESSSK----KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQG 128 Query: 775 DSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRL 834 + + QSS E+ + E ++ + ++ + P Sbjct: 129 KRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSY-PDD 187 Query: 835 PPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKS 894 P+ ++ ++ + KK + + + + + + KK+KKK+H+KH K K+K+ KS Sbjct: 188 KPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247 Score = 45.4 bits (106), Expect = 2e-04 Identities = 32/114 (28%), Positives = 46/114 (40%), Gaps = 9/114 (7%) Query: 797 GETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKK 856 G T SV + P P++ K Q++ ++ L E E KK Sbjct: 21 GPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAE---------FEEKMNENWKK 71 Query: 857 NKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910 +K + K + KK+ RK K K K SSS SS SSDS+ +E+ Sbjct: 72 ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEK 125 Score = 34.7 bits (78), Expect = 0.42 Identities = 47/222 (21%), Positives = 77/222 (34%), Gaps = 60/222 (27%) Query: 664 ASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEE 723 +S ++ + + KS + S +S S SE + K K+ S ++ Sbjct: 87 SSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146 Query: 724 HAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGS 783 H E + ++V K ++ E E + L + S D+K SSE Sbjct: 147 HESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSE------------- 193 Query: 784 GEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNAR 843 SS ++D E +K + +ERE+ Sbjct: 194 ------SSSESDYEEDVQAK----------------KKRRCEEREQ-------------- 217 Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGK 885 KEK KK K KK+H++ +KKKK HK + Sbjct: 218 ------AKEKVKKKK-----KKQHKKHSKKKKKKSGSSHKSR 248 Score = 34.3 bits (77), Expect = 0.55 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 852 EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSD 908 E ++K+ K KK+ + + EK+K R K K K+ +K SSESS SD + D Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRK-KSYPDDKPLSSESSSESDYEED 203 Score = 31.2 bits (69), Expect = 4.7 Identities = 17/52 (32%), Positives = 22/52 (42%) Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901 + E K K K K + +KEK + K K + KP S SS SD Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESD 199 >gi|40068059 CBF1 interacting corepressor [Homo sapiens] Length = 450 Score = 47.0 bits (110), Expect = 8e-05 Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 1/81 (1%) Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSS 903 ++L QK+K + D+ + KK+ + +K+KK + + KHK K K+ SSSS SS + Sbjct: 214 KSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHK-KHKSSSSSSSSSSSSSSTE 272 Query: 904 DSQSDEETADVSPQELLRRLK 924 S+S E+ + ++ ++R K Sbjct: 273 TSESSSESESNNKEKKIQRKK 293 Score = 46.2 bits (108), Expect = 1e-04 Identities = 35/89 (39%), Positives = 46/89 (51%), Gaps = 4/89 (4%) Query: 847 EVPQKEKHKKNKDKHKAK---KEHRRKKEKKKKHRKHKHKGKQKNK-KPEKSSSSESSDS 902 E P+ E K K K K K R +K+KKKK RK K K ++K K KSSSS SS S Sbjct: 206 EDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSS 265 Query: 903 SDSQSDEETADVSPQELLRRLKSLPLRRQ 931 S S S E + S E + K + +++ Sbjct: 266 SSSSSTETSESSSESESNNKEKKIQRKKR 294 Score = 35.4 bits (80), Expect = 0.25 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 10/79 (12%) Query: 850 QKEKHKKNK----------DKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSES 899 Q++K KKNK +K K+KK ++ H + K K K + K E S Sbjct: 290 QRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSK 349 Query: 900 SDSSDSQSDEETADVSPQE 918 SDS T SP++ Sbjct: 350 WSHSDSDKKSRTHKHSPEK 368 Score = 33.1 bits (74), Expect = 1.2 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 16/77 (20%) Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKK----------------PEK 893 +K+K KK K + H +++ K+K R KH+ +++ K PEK Sbjct: 309 EKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEK 368 Query: 894 SSSSESSDSSDSQSDEE 910 S SS S EE Sbjct: 369 RGSERKEGSSRSHGREE 385 Score = 30.4 bits (67), Expect = 8.0 Identities = 15/70 (21%), Positives = 27/70 (38%) Query: 851 KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910 + KHKK+K + + + + K KK ++ ++ S + SD E Sbjct: 249 RSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSE 308 Query: 911 TADVSPQELL 920 D S + L Sbjct: 309 EKDKSKKRKL 318 Score = 30.4 bits (67), Expect = 8.0 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 12/74 (16%) Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHK------------HKGKQKNKKPEKSSSS 897 +K+ +K + K+K + E+K K +K K K K+K + + SS Sbjct: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345 Query: 898 ESSDSSDSQSDEET 911 E S S S SD+++ Sbjct: 346 EDSKWSHSDSDKKS 359 >gi|11067749 bromodomain containing protein 3 [Homo sapiens] Length = 726 Score = 47.0 bits (110), Expect = 8e-05 Identities = 48/194 (24%), Positives = 80/194 (41%), Gaps = 42/194 (21%) Query: 749 PSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVP 808 P++ A S E S SSE+ DS S ++++ +L E H + Sbjct: 423 PALPAPAAPMVSKGAESSRSSEESSSDS----GSSDSEEERATRLAELQEQLKAVHEQLA 478 Query: 809 APQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHR 868 A + P + P +K E +KEK KK+K+K K K + + Sbjct: 479 ALSQAPVNKPKKKK------------------------EKKEKEKKKKDKEKEKEKHKVK 514 Query: 869 RKKEKKKKHRKHKHKGKQKNKKPEKSSSS------------ESSDSSDSQSDEETADVSP 916 ++EKK K + +QK +K++S+ ++S S DS+ +EE +S Sbjct: 515 AEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSY 574 Query: 917 QELLRRLKSLPLRR 930 E +R SL + R Sbjct: 575 DE--KRQLSLDINR 586 Score = 41.2 bits (95), Expect = 0.005 Identities = 78/378 (20%), Positives = 140/378 (37%), Gaps = 65/378 (17%) Query: 596 SAVKMKMFGKLTRDTFEWHPDKLL----CKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFL 651 S VK KM G+ D + D L C ++N PD +V + R +D + + F Sbjct: 359 STVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPD----HEVVAMARKLQDVFEM-RFA 413 Query: 652 TLP----ETASLPTTQA-----------SSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSI 696 +P E +LP A SSE+ S G S + ++ +++ ++ Sbjct: 414 KMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAV 473 Query: 697 SEFLS-LARSKAEPPKQQSSPLVNKE---------EEHAPELSANQTVNKDVDAQAEGEG 746 E L+ L+++ PK++ ++ E+H + + A+ + Sbjct: 474 HEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQK 533 Query: 747 SRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAG---SGEANFQSSQDTD------LG 797 P+ A +K DSE+++ G S + Q S D + LG Sbjct: 534 KAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLG 593 Query: 798 ETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKN 857 + + P+ ++ P +++ID E P + L+ Q++ + Sbjct: 594 RVVHIIQSREPSLRDSNPD----EIEIDF-ETLKPTTLRELERYVKSCLQKKQRKPFSAS 648 Query: 858 KDKHKAKKEHRRKKEKKK-----------------KHRKHKHKGKQKNKKPEKSSSSESS 900 K AK + +EKKK K + + G + P + SSS SS Sbjct: 649 GKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSS 708 Query: 901 DSSDSQSDEETADVSPQE 918 +S S S ++D S E Sbjct: 709 ESGSSSSSGSSSDSSDSE 726 >gi|42718020 retinitis pigmentosa 9 [Homo sapiens] Length = 221 Score = 47.0 bits (110), Expect = 8e-05 Identities = 20/60 (33%), Positives = 38/60 (63%) Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS 902 +Q LE ++ + + + K++H++KK+K+K ++ K K K+K +K + S S+E SDS Sbjct: 161 KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220 Score = 35.4 bits (80), Expect = 0.25 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%) Query: 859 DKHKAKKEHRRKKEKKKK-HRKHKHKGKQKNKKPEKS---SSSESSDSSDSQ 906 D+ ++ KEK KK +K KHK ++K KK +K SS+S++ SDS+ Sbjct: 170 DEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221 >gi|87299628 biorientation of chromosomes in cell division 1-like [Homo sapiens] Length = 3051 Score = 46.6 bits (109), Expect = 1e-04 Identities = 46/234 (19%), Positives = 90/234 (38%), Gaps = 15/234 (6%) Query: 666 SEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHA 725 S + + + K + ++D SK + + + + E K S NK + Sbjct: 328 SNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVE 387 Query: 726 PELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGD--SEDDQAGS 783 ++ DVD + S + + +E +S E+G+ S+D++ Sbjct: 388 GTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNK 447 Query: 784 GEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNAR 843 + D+ G+T SV HA V P + K D +E + R Sbjct: 448 QNKTKTQTSDSSEGKTKSVRHAYVHKP------YLYSKYYSDSDDE-------LTVEQRR 494 Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSS 897 Q++ ++E+ + + + +E R++K +K K K K +G+ E S+ S Sbjct: 495 QSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKS 548 Score = 38.5 bits (88), Expect = 0.029 Identities = 113/621 (18%), Positives = 222/621 (35%), Gaps = 102/621 (16%) Query: 379 PMVAATSENSHL-LQVLSESAGKATPDPGTHSKHQLNASKRAELLGETPIQGSATSVLEF 437 P++A ++E H V SAG+ P K + + + E+ G +G S L Sbjct: 2398 PVLAVSTEEGHNGPSVHKPSAGQGHPSAVCAEKEEKHGKECPEI-GPFAGRGQKESTLHL 2456 Query: 438 LSQKDKERIKEMKQATDLK-----------AAQLKARSLAQNAQSSRAQLSPAAAAGHCS 486 ++ ++K + Q D A+ R L NA S P +G + Sbjct: 2457 INAEEKNVLLNSLQKEDKSPETGTAGGSSTASYSAGRGLEGNANSPAHLRGPEQTSGQTA 2516 Query: 487 WNMALG------GGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMT 540 + ++ T +KA + P + FL +QG +D L+ S T Sbjct: 2517 KDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHS----FLPAEQQGSEDNLKT----STT 2568 Query: 541 EWERGRE------------------------------RDEFARAALLYASSHSTLSSRFT 570 + G+E +++++ AS+ T T Sbjct: 2569 KCITGQESKIAPSHTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQASAEKTGDDNST 2628 Query: 571 HAKEEDDSDQVEVPRDQEN--DVGDKQSAVK----MKMFGKLTRDTFEWHPDKLLCKRFN 624 ++ D + +EN D+G+++S + +K+ L + + ++ + Sbjct: 2629 RKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKLKANLKMEAYVPSEEEKNGEILA 2688 Query: 625 VPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKS-RKPSR 683 P+ G+ ++R+ V L + + + SE S ++G S RK + Sbjct: 2689 PPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSE--SYNKGEISSGRKDNA 2746 Query: 684 WDTSKHEKKED--SISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQ 741 S H + D + E + P +++ ++ E+E P+ + + ++ AQ Sbjct: 2747 EAISGHSVEADPKEVEE-----EERHMPKRKRKQHYLSSEDE--PDDNPDVLDSRIETAQ 2799 Query: 742 AEGEGSRP-------SMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDT 794 + + P S DL SS ++S E+ D +GE Q+ DT Sbjct: 2800 RQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDT 2859 Query: 795 DLGETSSVAHALVPAPQEPPPSFPIQ---KMQIDEREEFGPRLPPVFCPNARQTLEVPQK 851 + ++ + P +P++ KM+ D + + G + V + L+V Q Sbjct: 2860 IKSQEEDQP-IIIKRKRGRPRKYPVETTLKMKDDSKTDTG--IVTVEQSPSSSKLKVMQT 2916 Query: 852 EKHKKN--------------KDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSS 897 ++ K ++K R +K K+ + + +K +KS S Sbjct: 2917 DESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSD 2976 Query: 898 ESSDSSDSQSDEETADVSPQE 918 D + +SDEE + E Sbjct: 2977 PVEDKKEQESDEEEEEEEEDE 2997 Score = 36.6 bits (83), Expect = 0.11 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%) Query: 851 KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910 KEK+K +KD + E RK K R KH K KK E S + DS ++ Sbjct: 998 KEKYKSDKDSTSTRLE--RKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKA 1055 Query: 911 TADVSPQE--LLRRL 923 + S E L RRL Sbjct: 1056 RGNSSLMEKKLSRRL 1070 Score = 32.3 bits (72), Expect = 2.1 Identities = 42/185 (22%), Positives = 76/185 (41%), Gaps = 32/185 (17%) Query: 721 EEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ 780 +E A S + K + ++ S+P+ D +S +K +SED D E Sbjct: 213 QEASAARASTETSNAKTSERASKKLPSQPTTD--------TSTDKERTSED-MADKEKST 263 Query: 781 AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQI-----DEREEFGPRLP 835 A SG +++ ++ E S + P P E ++ + + D ++E Sbjct: 264 ADSGGEGLETAPKSE--EFSDL-----PCPVEEIKNYTKEHNNLILLNKDVQQE------ 310 Query: 836 PVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKH-RKHKHKGKQKNKKPEKS 894 + ++ + EK + +K + KKE + K EKK H +K + K K++K K Sbjct: 311 ----SSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKE 366 Query: 895 SSSES 899 ES Sbjct: 367 KEVES 371 Score = 32.0 bits (71), Expect = 2.8 Identities = 47/264 (17%), Positives = 100/264 (37%), Gaps = 53/264 (20%) Query: 536 DPSMTEWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQ 595 +P T+ E R+ +E + + S ++ +SR K+E S + + ++ND Sbjct: 2806 EPHDTKEENSRDLEELPKTS----SETNSTTSRVMEEKDEYSSSETTGEKPEQND----D 2857 Query: 596 SAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPE 655 +K + E ++ ++ P YP T + ++K D + +T+ + Sbjct: 2858 DTIKSQ----------EEDQPIIIKRKRGRPRKYPVETTL---KMKDDSKTDTGIVTVEQ 2904 Query: 656 TASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSS 715 + S +S KV Q D+S K + + +D + ++ R + PK+ Sbjct: 2905 SPS-----SSKLKVMQ---TDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKR--- 2953 Query: 716 PLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGD 775 + TV+ D E S P +++ D+K S++E+ + Sbjct: 2954 ---------------SLTVSDDA------ESSEPERKRQKSVSDPVEDKKEQESDEEEEE 2992 Query: 776 SEDDQAGSGEANFQSSQDTDLGET 799 E+D+ + + +T Sbjct: 2993 EEEDEPSGATTRSTTRSEAQRSKT 3016 Score = 31.2 bits (69), Expect = 4.7 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 10/75 (13%) Query: 847 EVPQKEKHKKNKDKHKAKKE-------HRRKKEKKKKHRKHKHKGKQKNK---KPEKSSS 896 +V Q+ +KNK K +K+ R+K++K+K +K H K ++ K EK + Sbjct: 306 DVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAK 365 Query: 897 SESSDSSDSQSDEET 911 + +S S++ + Sbjct: 366 EKEVESLKLPSEKNS 380 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.128 0.366 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 40,191,056 Number of Sequences: 37866 Number of extensions: 2100730 Number of successful extensions: 21024 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 366 Number of HSP's successfully gapped in prelim test: 495 Number of HSP's that attempted gapping in prelim test: 11808 Number of HSP's gapped (non-prelim): 5815 length of query: 931 length of database: 18,247,518 effective HSP length: 112 effective length of query: 819 effective length of database: 14,006,526 effective search space: 11471344794 effective search space used: 11471344794 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.