Guide to the Human Genome
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Search of human proteins with 21361684

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21361684 G patch domain containing 1 [Homo sapiens]
         (931 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21361684 G patch domain containing 1 [Homo sapiens]               1873   0.0  
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    53   2e-06
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    53   2e-06
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    53   2e-06
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]            52   3e-06
gi|56090620 NFKB activating protein-like [Homo sapiens]                52   3e-06
gi|168229156 NFKB activating protein [Homo sapiens]                    52   3e-06
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    52   3e-06
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    52   3e-06
gi|221219020 NYD-SP11 protein [Homo sapiens]                           51   4e-06
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         51   4e-06
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         51   4e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     51   6e-06
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    50   7e-06
gi|217330641 IWS1 homolog [Homo sapiens]                               50   7e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    50   1e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    50   1e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    49   2e-05
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]         49   2e-05
gi|39932583 hypothetical protein LOC55051 isoform 1 [Homo sapiens]     49   2e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    49   3e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    49   3e-05
gi|4507347 TBP-associated factor 2 [Homo sapiens]                      49   3e-05
gi|8923271 coiled-coil domain containing 49 [Homo sapiens]             48   4e-05
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    48   5e-05
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              47   6e-05
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                47   8e-05
gi|11067749 bromodomain containing protein 3 [Homo sapiens]            47   8e-05
gi|42718020 retinitis pigmentosa 9 [Homo sapiens]                      47   8e-05
gi|87299628 biorientation of chromosomes in cell division 1-like...    47   1e-04

>gi|21361684 G patch domain containing 1 [Homo sapiens]
          Length = 931

 Score = 1873 bits (4851), Expect = 0.0
 Identities = 931/931 (100%), Positives = 931/931 (100%)

Query: 1   MAARDSDSEEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAG 60
           MAARDSDSEEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAG
Sbjct: 1   MAARDSDSEEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAG 60

Query: 61  YFNTVGSKEGWTPSTFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKT 120
           YFNTVGSKEGWTPSTFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKT
Sbjct: 61  YFNTVGSKEGWTPSTFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKT 120

Query: 121 KDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPR 180
           KDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPR
Sbjct: 121 KDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPR 180

Query: 181 RQKPDPGVKIYGCALPPGSSEGSEGEDDDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKG 240
           RQKPDPGVKIYGCALPPGSSEGSEGEDDDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKG
Sbjct: 181 RQKPDPGVKIYGCALPPGSSEGSEGEDDDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKG 240

Query: 241 LDPHQALFGTSGEHFNLFSGGSERAGDLGEIGLNKGRKLGISGQAFGVGALEEEDDDIYA 300
           LDPHQALFGTSGEHFNLFSGGSERAGDLGEIGLNKGRKLGISGQAFGVGALEEEDDDIYA
Sbjct: 241 LDPHQALFGTSGEHFNLFSGGSERAGDLGEIGLNKGRKLGISGQAFGVGALEEEDDDIYA 300

Query: 301 TETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKK 360
           TETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKK
Sbjct: 301 TETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKK 360

Query: 361 IYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAE 420
           IYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAE
Sbjct: 361 IYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAE 420

Query: 421 LLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAA 480
           LLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAA
Sbjct: 421 LLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAA 480

Query: 481 AAGHCSWNMALGGGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMT 540
           AAGHCSWNMALGGGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMT
Sbjct: 481 AAGHCSWNMALGGGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMT 540

Query: 541 EWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKM 600
           EWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKM
Sbjct: 541 EWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKM 600

Query: 601 KMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLP 660
           KMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLP
Sbjct: 601 KMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLP 660

Query: 661 TTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNK 720
           TTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNK
Sbjct: 661 TTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNK 720

Query: 721 EEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ 780
           EEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ
Sbjct: 721 EEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ 780

Query: 781 AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCP 840
           AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCP
Sbjct: 781 AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCP 840

Query: 841 NARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS 900
           NARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS
Sbjct: 841 NARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS 900

Query: 901 DSSDSQSDEETADVSPQELLRRLKSLPLRRQ 931
           DSSDSQSDEETADVSPQELLRRLKSLPLRRQ
Sbjct: 901 DSSDSQSDEETADVSPQELLRRLKSLPLRRQ 931


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 27/88 (30%), Positives = 46/88 (52%)

Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSS 903
           +T E  +KE  +K K K K K++ ++KK K+ + RK K + ++K K+  K    E     
Sbjct: 18  ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77

Query: 904 DSQSDEETADVSPQELLRRLKSLPLRRQ 931
           + + +EE  +   +E  RR K    RR+
Sbjct: 78  EEEEEEEEKEEEEKEEGRRRKKKKKRRR 105



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 7/95 (7%)

Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQK-------NKKPEKSSS 896
           +T E  + E+ ++ + K K K++ +RK+++KKK  K   K K+K        +K +K   
Sbjct: 12  ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71

Query: 897 SESSDSSDSQSDEETADVSPQELLRRLKSLPLRRQ 931
            E  +  + + +EE  +   +E  RR K    RR+
Sbjct: 72  EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 17/59 (28%), Positives = 33/59 (55%)

Query: 852 EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910
           +K KK K + +  +E    +E+++K  K K K K+K K+ EK   ++ ++    + +EE
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 14/48 (29%), Positives = 33/48 (68%)

Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKS 894
           E  ++E+ ++ ++K + +KE  R+++KKKK R+ + + ++K K+  K+
Sbjct: 73  EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 19/82 (23%), Positives = 40/82 (48%), Gaps = 6/82 (7%)

Query: 850 QKEKHKKNKDKHKAK------KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSS 903
           +KEK KK K+  K K      K+ +RK++KKK+  + + + +++ ++ E+    E     
Sbjct: 39  EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRK 98

Query: 904 DSQSDEETADVSPQELLRRLKS 925
             +      +   ++  RR K+
Sbjct: 99  KKKKRRRKEEEEEKKKKRRRKT 120



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 15/41 (36%), Positives = 28/41 (68%)

Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQK 887
           E  ++E+ K+   + K KK+ RRK+E+++K +K + K K+K
Sbjct: 83  EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 15/60 (25%), Positives = 35/60 (58%), Gaps = 4/60 (6%)

Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKE----KKKKHRKHKHKGKQKNKKPEKSSSSE 898
           R+  +  ++E+ ++ +++ + +KE   K+E    KKKK R+ K + ++K KK  + +  +
Sbjct: 64  RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 52/255 (20%), Positives = 107/255 (41%), Gaps = 27/255 (10%)

Query: 657  ASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARS-KAEPPKQQSS 715
            A+  T + + E  S  + P K R+    +   +  KE S ++ L +    + +  K+Q +
Sbjct: 1513 ATYDTKRPNEETKSVDKNPCKDREKHVLEARNN--KESSGNKLLYILNPPETQVEKEQIT 1570

Query: 716  PLVNKEE-EHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQG 774
              ++K   +  P+LS +  ++ D+  + +     P  +       S S+   S  E+E  
Sbjct: 1571 GQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYN------ESDSESNVSVKEEESS 1624

Query: 775  -----DSEDDQAGSGEANFQSSQDTDLGETSSVAHA---LVPAPQEPPPSFPIQKMQIDE 826
                 D +D      + +  ++    +G + + +H+   + P+    P           +
Sbjct: 1625 GNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSG--------SQ 1676

Query: 827  REEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQ 886
                          ++++  +  +K+KHKK+K KHK  K+H   + + +K +KHKHK K+
Sbjct: 1677 TRSHSSSASSAESQDSKKKKKKKEKKKHKKHK-KHKKHKKHAGTEVELEKSQKHKHKKKK 1735

Query: 887  KNKKPEKSSSSESSD 901
              K  +K    E  D
Sbjct: 1736 SKKNKDKEKEKEKDD 1750



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 56/256 (21%), Positives = 99/256 (38%), Gaps = 28/256 (10%)

Query: 676  DKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735
            + SRK SR  T   E K DS+  F+  +R  A P + +       + E     S ++   
Sbjct: 921  ETSRK-SREPTGVEENKTDSL--FVLPSRDDATPVRDEPM-----DAESITFKSVSEKDK 972

Query: 736  KDVDA-QAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDT 794
            ++ D  +A+G+ ++   D   A+    +  K +    E+ D E +++   E   + +++ 
Sbjct: 973  RERDKPKAKGDKTKRKND-GSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEE 1031

Query: 795  DLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854
                         P       S   QK   DE+    PR          Q  +  ++EK 
Sbjct: 1032 ------------TPKTDNTKSSSSSQK---DEKITGTPRKAHSKSAKEHQETKPVKEEKV 1076

Query: 855  KKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADV 914
            KK+  K    ++   K+EK KK  +   K K  + K EK          D   +  +  +
Sbjct: 1077 KKDYSKDVKSEKLTTKEEKAKKPNE---KNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI 1133

Query: 915  SPQELLRRLKSLPLRR 930
            S  E+   +K  P R+
Sbjct: 1134 SKLEVTEIVKPSPKRK 1149



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 14/167 (8%)

Query: 663  QASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEE 722
            +A S+   +H+      KP + +  K +  +D  SE L+    KA+ P +++ PL NK E
Sbjct: 1056 KAHSKSAKEHQ----ETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1111

Query: 723  EHAPELSANQTVNKDVDAQAEGEGSRPS-MDLFRAIFASSSDEKSSSSEDEQGDSEDDQ- 780
            +        +T  K VD   E    + S +++   +  S   +    +E      E D+ 
Sbjct: 1112 KR-----KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI 1166

Query: 781  ---AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQI 824
               A + +          +G T ++++   P+ +    S  +++ ++
Sbjct: 1167 SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKV 1213



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 71/344 (20%), Positives = 125/344 (36%), Gaps = 55/344 (15%)

Query: 558  YASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDK 617
            Y S+ ST  S    ++E+ D+ +  +   +E +  +   A  + +  ++ +   +W  D 
Sbjct: 1234 YTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQS--KWDKDD 1291

Query: 618  LLCKRFNVPDPYPDSTLVGLPR--VKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGP 675
               +  +V    P S+ VG P   +K       N +  PE  S P     SEK+      
Sbjct: 1292 FESEEEDVKSTQPISS-VGKPASVIKNVSTKPSNIVKYPEKESEP-----SEKIQ----- 1340

Query: 676  DKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735
             K  K    +  +HE K    S     A S+    K +   ++ KE     + S      
Sbjct: 1341 -KFTKDVSHEIIQHEVKSSKNS-----ASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKE 1394

Query: 736  KDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTD 795
             ++D   E +G+      F+++  SS + ++S   D    S +        N     D D
Sbjct: 1395 SNLDRLNE-QGN------FKSLSQSSKEARTSDKHDSTRASSNKDF---TPNRDKKTDYD 1444

Query: 796  LGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHK 855
              E SS                     + DE+ E   R      P+  +     QK K +
Sbjct: 1445 TREYSS-------------------SKRRDEKNELTRRKDS---PSRNKDSASGQKNKPR 1482

Query: 856  KNKD-KHKAKKEHRRKKEKKKKHRK-HKHKGKQKNKKPEKSSSS 897
            + +D   K   + ++      + RK H HK     K+P + + S
Sbjct: 1483 EERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1526



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 39/239 (16%), Positives = 88/239 (36%), Gaps = 20/239 (8%)

Query: 682  SRWDTSKHEKKEDSI--SEFLSLARSKAEPPKQQS---SPLVNKEEEHAPELSANQTVNK 736
            S+WD    E +E+ +  ++ +S     A   K  S   S +V   E+ +      Q   K
Sbjct: 1285 SKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTK 1344

Query: 737  DVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDL 796
            DV  +      + S +       S+S EK  + + +    E +     + + Q  ++++L
Sbjct: 1345 DVSHEIIQHEVKSSKN-------SASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNL 1397

Query: 797  GETSSVAH--ALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854
               +   +  +L  + +E   S      +    ++F P        + +   +  +    
Sbjct: 1398 DRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNR------DKKTDYDTREYSSS 1451

Query: 855  KKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETAD 913
            K+  +K++  +        K      K+K +++   P+K +      +S    D +  D
Sbjct: 1452 KRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHD 1510


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 52/255 (20%), Positives = 107/255 (41%), Gaps = 27/255 (10%)

Query: 657  ASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARS-KAEPPKQQSS 715
            A+  T + + E  S  + P K R+    +   +  KE S ++ L +    + +  K+Q +
Sbjct: 1547 ATYDTKRPNEETKSVDKNPCKDREKHVLEARNN--KESSGNKLLYILNPPETQVEKEQIT 1604

Query: 716  PLVNKEE-EHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQG 774
              ++K   +  P+LS +  ++ D+  + +     P  +       S S+   S  E+E  
Sbjct: 1605 GQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYN------ESDSESNVSVKEEESS 1658

Query: 775  -----DSEDDQAGSGEANFQSSQDTDLGETSSVAHA---LVPAPQEPPPSFPIQKMQIDE 826
                 D +D      + +  ++    +G + + +H+   + P+    P           +
Sbjct: 1659 GNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSG--------SQ 1710

Query: 827  REEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQ 886
                          ++++  +  +K+KHKK+K KHK  K+H   + + +K +KHKHK K+
Sbjct: 1711 TRSHSSSASSAESQDSKKKKKKKEKKKHKKHK-KHKKHKKHAGTEVELEKSQKHKHKKKK 1769

Query: 887  KNKKPEKSSSSESSD 901
              K  +K    E  D
Sbjct: 1770 SKKNKDKEKEKEKDD 1784



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 56/256 (21%), Positives = 99/256 (38%), Gaps = 28/256 (10%)

Query: 676  DKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735
            + SRK SR  T   E K DS+  F+  +R  A P + +       + E     S ++   
Sbjct: 955  ETSRK-SREPTGVEENKTDSL--FVLPSRDDATPVRDEPM-----DAESITFKSVSEKDK 1006

Query: 736  KDVDA-QAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDT 794
            ++ D  +A+G+ ++   D   A+    +  K +    E+ D E +++   E   + +++ 
Sbjct: 1007 RERDKPKAKGDKTKRKND-GSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEE 1065

Query: 795  DLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854
                         P       S   QK   DE+    PR          Q  +  ++EK 
Sbjct: 1066 ------------TPKTDNTKSSSSSQK---DEKITGTPRKAHSKSAKEHQETKPVKEEKV 1110

Query: 855  KKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADV 914
            KK+  K    ++   K+EK KK  +   K K  + K EK          D   +  +  +
Sbjct: 1111 KKDYSKDVKSEKLTTKEEKAKKPNE---KNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI 1167

Query: 915  SPQELLRRLKSLPLRR 930
            S  E+   +K  P R+
Sbjct: 1168 SKLEVTEIVKPSPKRK 1183



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 14/167 (8%)

Query: 663  QASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEE 722
            +A S+   +H+      KP + +  K +  +D  SE L+    KA+ P +++ PL NK E
Sbjct: 1090 KAHSKSAKEHQ----ETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGE 1145

Query: 723  EHAPELSANQTVNKDVDAQAEGEGSRPS-MDLFRAIFASSSDEKSSSSEDEQGDSEDDQ- 780
            +        +T  K VD   E    + S +++   +  S   +    +E      E D+ 
Sbjct: 1146 KR-----KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKI 1200

Query: 781  ---AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQI 824
               A + +          +G T ++++   P+ +    S  +++ ++
Sbjct: 1201 SLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKV 1247



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 71/344 (20%), Positives = 125/344 (36%), Gaps = 55/344 (15%)

Query: 558  YASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDK 617
            Y S+ ST  S    ++E+ D+ +  +   +E +  +   A  + +  ++ +   +W  D 
Sbjct: 1268 YTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQS--KWDKDD 1325

Query: 618  LLCKRFNVPDPYPDSTLVGLPR--VKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGP 675
               +  +V    P S+ VG P   +K       N +  PE  S P     SEK+      
Sbjct: 1326 FESEEEDVKSTQPISS-VGKPASVIKNVSTKPSNIVKYPEKESEP-----SEKIQ----- 1374

Query: 676  DKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735
             K  K    +  +HE K    S     A S+    K +   ++ KE     + S      
Sbjct: 1375 -KFTKDVSHEIIQHEVKSSKNS-----ASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKE 1428

Query: 736  KDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTD 795
             ++D   E +G+      F+++  SS + ++S   D    S +        N     D D
Sbjct: 1429 SNLDRLNE-QGN------FKSLSQSSKEARTSDKHDSTRASSNKDF---TPNRDKKTDYD 1478

Query: 796  LGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHK 855
              E SS                     + DE+ E   R      P+  +     QK K +
Sbjct: 1479 TREYSS-------------------SKRRDEKNELTRRKDS---PSRNKDSASGQKNKPR 1516

Query: 856  KNKD-KHKAKKEHRRKKEKKKKHRK-HKHKGKQKNKKPEKSSSS 897
            + +D   K   + ++      + RK H HK     K+P + + S
Sbjct: 1517 EERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1560



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 39/239 (16%), Positives = 88/239 (36%), Gaps = 20/239 (8%)

Query: 682  SRWDTSKHEKKEDSI--SEFLSLARSKAEPPKQQS---SPLVNKEEEHAPELSANQTVNK 736
            S+WD    E +E+ +  ++ +S     A   K  S   S +V   E+ +      Q   K
Sbjct: 1319 SKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTK 1378

Query: 737  DVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDL 796
            DV  +      + S +       S+S EK  + + +    E +     + + Q  ++++L
Sbjct: 1379 DVSHEIIQHEVKSSKN-------SASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNL 1431

Query: 797  GETSSVAH--ALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854
               +   +  +L  + +E   S      +    ++F P        + +   +  +    
Sbjct: 1432 DRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNR------DKKTDYDTREYSSS 1485

Query: 855  KKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETAD 913
            K+  +K++  +        K      K+K +++   P+K +      +S    D +  D
Sbjct: 1486 KRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHD 1544


>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 170

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 24/52 (46%), Positives = 34/52 (65%)

Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
           +K+K KK K K K KK+ ++KK+KKKK RK K K K+K KK  K    ++ +
Sbjct: 113 KKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 23/51 (45%), Positives = 36/51 (70%)

Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS 900
           +K+K KK K K K KK+ ++KK+K+K+ RK K K K+K KK +K + +E +
Sbjct: 117 KKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGA 167



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 24/64 (37%), Positives = 38/64 (59%)

Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS 902
           R+  +  +KEK KK K K K KK+ ++KK+KKKK +K K K K+K K+  K    +    
Sbjct: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161

Query: 903 SDSQ 906
           + ++
Sbjct: 162 TGNE 165



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 25/50 (50%), Positives = 33/50 (66%)

Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK 893
           Q  E  +KEK KK K K K KK+ ++KK+KKKK +K K K K+K K+  K
Sbjct: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRK 150



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 24/65 (36%), Positives = 37/65 (56%)

Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDE 909
           +KEK K+ K K K KK+ ++KK+KKKK +K K K K+K K+  K    +       ++  
Sbjct: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164

Query: 910 ETADV 914
           E A +
Sbjct: 165 EGAKI 169



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 23/46 (50%), Positives = 35/46 (76%), Gaps = 1/46 (2%)

Query: 848 VPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK 893
           +PQ+E+ KK K+K K KK+ ++KK+KKKK +K K K K+K KK ++
Sbjct: 99  LPQREE-KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKR 143



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 22/56 (39%), Positives = 36/56 (64%), Gaps = 1/56 (1%)

Query: 838 FCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK 893
           FC +A  +L +P     ++ + K K K++ ++KK+KKKK +K K K K+K KK +K
Sbjct: 85  FC-DAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKK 139


>gi|56090620 NFKB activating protein-like [Homo sapiens]
          Length = 402

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 57/232 (24%), Positives = 87/232 (37%), Gaps = 27/232 (11%)

Query: 687 SKHEKKEDSISEFLSLARSKAEPPKQQS--SPLVNKEEEHAPELSANQTVNKDVDAQA-- 742
           S+    ED +        S   PP  QS  S        H+      +    ++D  A  
Sbjct: 5   SRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDVGALY 64

Query: 743 --EGEGSRPSMDLFRAI-FASS-SDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGE 798
                GSR  +  FR   FASS S   S         +E+ Q+       +S +   L E
Sbjct: 65  PFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQRRLKE 124

Query: 799 TSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNK 858
              +     P    P P FP    Q+D  E                 +E  ++  H+K+ 
Sbjct: 125 RERIGELGAPEVWGPSPKFP----QLDSDEH--------------TPVEDEEEVTHQKSS 166

Query: 859 DKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910
                 +EHR+KK  + +++K K K K   +K  K S S+S+  SD+ SD +
Sbjct: 167 SSDSNSEEHRKKKTSRSRNKK-KRKNKSSKRKHRKYSDSDSNSESDTNSDSD 217


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 30/83 (36%), Positives = 40/83 (48%), Gaps = 23/83 (27%)

Query: 851 KEKHKKNKDKHKAKKEH-----------------------RRKKEKKKKHRKHKHKGKQK 887
           KE+ KK + K  +K++H                       RR K+ KKK +K KH+ K+ 
Sbjct: 190 KERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKY 249

Query: 888 NKKPEKSSSSESSDSSDSQSDEE 910
            KK  K S  ESSDSS  +S EE
Sbjct: 250 KKKRSKKSRKESSDSSSKESQEE 272



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 19/64 (29%), Positives = 33/64 (51%)

Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDE 909
           + E+ KK+       +E ++KK  + K R  K + K+ +K+  K  S +S   SDS++D 
Sbjct: 164 EDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDS 223

Query: 910 ETAD 913
              D
Sbjct: 224 SDED 227



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 2/64 (3%)

Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQ 906
           E P+K     +  + + KK+  R KE+ KK RK K   K+K+KK  + S S+S   +DS 
Sbjct: 166 EEPKKSTTSASTSEEEKKKKSSRSKERSKKRRK-KKSSKRKHKKYSEDSDSDSDSETDS- 223

Query: 907 SDEE 910
           SDE+
Sbjct: 224 SDED 227



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 6/89 (6%)

Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS 902
           + T      E+ KK K    ++ + R KK +KKK  K KHK   K  +   S S   +DS
Sbjct: 170 KSTTSASTSEEEKKKKS---SRSKERSKKRRKKKSSKRKHK---KYSEDSDSDSDSETDS 223

Query: 903 SDSQSDEETADVSPQELLRRLKSLPLRRQ 931
           SD  +         +E  ++ +S   +++
Sbjct: 224 SDEDNKRRAKKAKKKEKKKKHRSKKYKKK 252



 Score = 33.5 bits (75), Expect = 0.95
 Identities = 49/241 (20%), Positives = 86/241 (35%), Gaps = 50/241 (20%)

Query: 664 ASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEE 723
           +SS     +  P  S KP  W +   +++E+S+       R K    +++   L      
Sbjct: 96  SSSVYYGSYSRPYGSDKP--WPSLLDKEREESL-------RQKRLSERERIGEL------ 140

Query: 724 HAPELSANQTVNK--DVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQA 781
            APE+      N   D D     E   P      A  +    +K SS   E+      + 
Sbjct: 141 GAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKK 200

Query: 782 GSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPN 841
            S   + + S+D+D    S                      + D  +E           N
Sbjct: 201 SSKRKHKKYSEDSDSDSDS----------------------ETDSSDE----------DN 228

Query: 842 ARQTLEVPQKEKHKKNKDK-HKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS 900
            R+  +  +KEK KK++ K +K K+  + +KE      K   +   +N   +++ + E S
Sbjct: 229 KRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPS 288

Query: 901 D 901
           D
Sbjct: 289 D 289


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 51/250 (20%), Positives = 104/250 (41%), Gaps = 19/250 (7%)

Query: 662 TQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKE 721
           + + S+K S + G  +     +   SK  +K  S  +  S++ S+ E  +  S      +
Sbjct: 142 SDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSD 201

Query: 722 EEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQA 781
           ++  PE        K    +A   G        +A  AS SD K+ S   +       ++
Sbjct: 202 QDFTPE--------KKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARS 253

Query: 782 GSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPN 841
            S  ++  SS D+D+           P     P   P+ K +  + +   P  PP    +
Sbjct: 254 ASSSSSSSSSSDSDVSVKK-------PPRGRKPAEKPLPKPRGRKPK---PERPPSSSSS 303

Query: 842 ARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGK-QKNKKPEKSSSSESS 900
              + EV +  + K+  +  + + E RR++E++++ R+ + + K +K ++ E++   E+ 
Sbjct: 304 DSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAE 363

Query: 901 DSSDSQSDEE 910
             S   S +E
Sbjct: 364 RGSGGSSGDE 373



 Score = 33.5 bits (75), Expect = 0.95
 Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 9/100 (9%)

Query: 694 DSISEFLSLARSKAEPPKQQSSPLVNK---EEEHAPELSANQTVNKDVDAQAEGEGSRPS 750
           +  +E  +  +S+   PK ++   VNK   E+E A E  A + +  +   Q + E  +PS
Sbjct: 537 EKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAE-DKPS 595

Query: 751 MDLFRAIFASSSDEKSSSSED---EQG-DSED-DQAGSGE 785
            DL   +   ++ +K  S+ED   E+G DSE+  + GS E
Sbjct: 596 TDLSAPVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSE 635



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 68/330 (20%), Positives = 108/330 (32%), Gaps = 50/330 (15%)

Query: 631 DSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHE 690
           D    G  +   +KY +F F T  ETA L       +     +  DK  KP+     K +
Sbjct: 26  DDIADGAVKPPPNKYPIFFFGT-HETAFL----GPKDLFPYDKCKDKYGKPN-----KRK 75

Query: 691 KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPS 750
              + + E  +   +    P     P V+  +  APE  AN     D D   E  G    
Sbjct: 76  GFNEGLWEIQNNPHASYSAP-----PPVSSSDSEAPE--ANPADGSDADEDDEDRG---- 124

Query: 751 MDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAP 810
           +    A+ A+++ ++  S  D    S++          + S      + SS       +P
Sbjct: 125 VMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSP 184

Query: 811 QEPPPSFPIQKMQIDEREEFGP------RLPPVFCPNARQTLEVPQKEKHKKNKDKHKAK 864
            E   S    + +    ++F P      R P       R+  + P         D   AK
Sbjct: 185 SEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAK 244

Query: 865 KEH-----------------------RRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
            E                        ++    +K   K   K + +  KPE+  SS SSD
Sbjct: 245 PEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSD 304

Query: 902 SSDSQSDEETADVSPQELLRRLKSLPLRRQ 931
           S   + D  +      E  RR      RR+
Sbjct: 305 SDSDEVDRISEWKRRDEARRRELEARRRRE 334


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 51/250 (20%), Positives = 104/250 (41%), Gaps = 19/250 (7%)

Query: 662 TQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKE 721
           + + S+K S + G  +     +   SK  +K  S  +  S++ S+ E  +  S      +
Sbjct: 142 SDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSD 201

Query: 722 EEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQA 781
           ++  PE        K    +A   G        +A  AS SD K+ S   +       ++
Sbjct: 202 QDFTPE--------KKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARS 253

Query: 782 GSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPN 841
            S  ++  SS D+D+           P     P   P+ K +  + +   P  PP    +
Sbjct: 254 ASSSSSSSSSSDSDVSVKK-------PPRGRKPAEKPLPKPRGRKPK---PERPPSSSSS 303

Query: 842 ARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGK-QKNKKPEKSSSSESS 900
              + EV +  + K+  +  + + E RR++E++++ R+ + + K +K ++ E++   E+ 
Sbjct: 304 DSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAE 363

Query: 901 DSSDSQSDEE 910
             S   S +E
Sbjct: 364 RGSGGSSGDE 373



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 9/116 (7%)

Query: 694 DSISEFLSLARSKAEPPKQQSSPLVNK---EEEHAPELSANQTVNKDVDAQAEGEGSRPS 750
           +  +E  +  +S+   PK ++   VNK   E+E A E  A + +  +   Q + E  +PS
Sbjct: 537 EKAAEVYTRLKSRVLGPKIEAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAE-DKPS 595

Query: 751 MDLFRAIFASSSDEKSSSSED---EQG-DSED-DQAGSGEANFQSSQDTDLGETSS 801
            DL   +   ++ +K  S+ED   E+G DSE+  + GS E      +  DL    S
Sbjct: 596 TDLSAPVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDLHDVREGPDLDRPGS 651



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 68/330 (20%), Positives = 108/330 (32%), Gaps = 50/330 (15%)

Query: 631 DSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHE 690
           D    G  +   +KY +F F T  ETA L       +     +  DK  KP+     K +
Sbjct: 26  DDIADGAVKPPPNKYPIFFFGT-HETAFL----GPKDLFPYDKCKDKYGKPN-----KRK 75

Query: 691 KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPS 750
              + + E  +   +    P     P V+  +  APE  AN     D D   E  G    
Sbjct: 76  GFNEGLWEIQNNPHASYSAP-----PPVSSSDSEAPE--ANPADGSDADEDDEDRG---- 124

Query: 751 MDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAP 810
           +    A+ A+++ ++  S  D    S++          + S      + SS       +P
Sbjct: 125 VMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSP 184

Query: 811 QEPPPSFPIQKMQIDEREEFGP------RLPPVFCPNARQTLEVPQKEKHKKNKDKHKAK 864
            E   S    + +    ++F P      R P       R+  + P         D   AK
Sbjct: 185 SEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAK 244

Query: 865 KEH-----------------------RRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
            E                        ++    +K   K   K + +  KPE+  SS SSD
Sbjct: 245 PEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSSSSD 304

Query: 902 SSDSQSDEETADVSPQELLRRLKSLPLRRQ 931
           S   + D  +      E  RR      RR+
Sbjct: 305 SDSDEVDRISEWKRRDEARRRELEARRRRE 334


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 59/261 (22%), Positives = 114/261 (43%), Gaps = 41/261 (15%)

Query: 684  WDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAE 743
            WD S  EK+ +   +   LAR + +   +    ++NKEE+   E S     + +V    E
Sbjct: 2123 WDFS--EKRSELTKDEKKLARKQRKLANKMRR-MINKEEKMTEEESKLARKHSEVILDDE 2179

Query: 744  GEGSRPSMDLFRAI---FASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETS 800
             EG     ++   +   +    + K      E+  S+ D+  S E +F    ++ L E  
Sbjct: 2180 EEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVES-EEHFSEEMESLLDELE 2238

Query: 801  SVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKD- 859
                      QE      +   + +EREE             R+  EV ++E+ +K ++ 
Sbjct: 2239 K---------QES-----LSSEEEEEREE----------EEEREEEEVREEEEERKEEEE 2274

Query: 860  ---KHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS-SDSQSDEETADVS 915
               K   K+E  +KK+KK+K ++   + ++  ++ E+  S E ++S SD + +EE+  + 
Sbjct: 2275 GEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334

Query: 916  PQ-----ELLRRLKSLPLRRQ 931
             +     E+L++ K   L+ Q
Sbjct: 2335 EEVDREKEILKKEKQFKLQEQ 2355


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 27/362 (7%)

Query: 573  KEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDS 632
            ++E D ++ E    +  +  +K+S +K K   K+ R TFE    K+  +  +  D    S
Sbjct: 780  EKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFE-KEKKIKHEHKSEKDKLDLS 838

Query: 633  TLVGLPRVKRDKYSVFNFLTLPE------TASLPTT---QASSEKVSQHRGPDKSRKPSR 683
              V   + K   YS        E      TA++  T   + S EK+ +    +K  K   
Sbjct: 839  ECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH 898

Query: 684  WDTSKHE---KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDA 740
               SK +   +K++  S+    ++S+    K++   L  KE+    E S N T +K +  
Sbjct: 899  LAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE-SINITNSKHIQE 957

Query: 741  QAEG---EGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLG 797
            + +    +G++   +   ++   + DE   + + ++ D +D      +   +  +  D  
Sbjct: 958  EKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYK---ERDKHKDKI 1014

Query: 798  ETSSVAHALVPAPQEPPPSFPIQK-MQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKK 856
            + +S+      A +  P S P  K  +  E+      L            ++  ++ HKK
Sbjct: 1015 QINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKK 1074

Query: 857  NKDKHKAKKEHRRKKE-----KKKKHRKHKHKGKQ-KNKKPEKSSSSESSDSSDSQSDEE 910
            +K+K K K++ R +       K K   K KH   + KNK+  +S SSE +D+   +   +
Sbjct: 1075 HKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPK 1134

Query: 911  TA 912
             A
Sbjct: 1135 DA 1136



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 40/184 (21%), Positives = 78/184 (42%), Gaps = 27/184 (14%)

Query: 741 QAEGEGSRP-------SMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQD 793
           QA   G RP        ++L        SD+  S ++ E+  S +  +     + ++ +D
Sbjct: 256 QANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKD 315

Query: 794 TDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEK 853
           + + E+  +  +  P P     +    + + D+ EE    +             + +KE+
Sbjct: 316 SLICESKQILPSKTPLPS----ALDEYEFKDDDDEEINKMI---------DDRHILRKEQ 362

Query: 854 HKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK--SSSSESSDSSDSQSDEET 911
            K+N+ +  A+K H   K++K  + K     K K +KP +   SS+ESSD    Q+ + +
Sbjct: 363 RKENEPE--AEKTHLFAKQEKAFYPK---SFKSKKQKPSRVLYSSTESSDEEALQNKKIS 417

Query: 912 ADVS 915
              S
Sbjct: 418 TSCS 421



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 62/276 (22%), Positives = 101/276 (36%), Gaps = 34/276 (12%)

Query: 654 PETASLPTTQASSEKVSQHRGPDKSRK--PSRWDTSKHEKKEDSISEFLSLARSKAEPPK 711
           P      +T++S E+  Q++    S    P   ++    KKE  +S             K
Sbjct: 395 PSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLK 454

Query: 712 QQSSPLVN---KEEEHAPELS--ANQTVNKDVDA----QAEGEGSRP-------SMDLFR 755
            Q+    N   K+E+   E +   N TVN  +D     + EG   +        S+ LF 
Sbjct: 455 NQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFH 514

Query: 756 AIFASSSDEKSSSSEDEQGDSEDDQA------GSGEANFQ-------SSQDTDLGETSSV 802
                S       SE +    + +        GS E + Q       +++   L E+SSV
Sbjct: 515 ISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSV 574

Query: 803 AHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHK 862
                    +    F ++  +    +       P F  N+  TL+  + +K  K   KHK
Sbjct: 575 KSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTF-ENSDCTLK--KMDKEGKTLKKHK 631

Query: 863 AKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSE 898
            K + R K++ KK+    K K K K+   E   S E
Sbjct: 632 LKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVE 667


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 78/362 (21%), Positives = 150/362 (41%), Gaps = 27/362 (7%)

Query: 573  KEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDS 632
            ++E D ++ E    +  +  +K+S +K K   K+ R TFE    K+  +  +  D    S
Sbjct: 803  EKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFE-KEKKIKHEHKSEKDKLDLS 861

Query: 633  TLVGLPRVKRDKYSVFNFLTLPE------TASLPTT---QASSEKVSQHRGPDKSRKPSR 683
              V   + K   YS        E      TA++  T   + S EK+ +    +K  K   
Sbjct: 862  ECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERH 921

Query: 684  WDTSKHE---KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDA 740
               SK +   +K++  S+    ++S+    K++   L  KE+    E S N T +K +  
Sbjct: 922  LAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE-SINITNSKHIQE 980

Query: 741  QAEG---EGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLG 797
            + +    +G++   +   ++   + DE   + + ++ D +D      +   +  +  D  
Sbjct: 981  EKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYK---ERDKHKDKI 1037

Query: 798  ETSSVAHALVPAPQEPPPSFPIQK-MQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKK 856
            + +S+      A +  P S P  K  +  E+      L            ++  ++ HKK
Sbjct: 1038 QINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKK 1097

Query: 857  NKDKHKAKKEHRRKKE-----KKKKHRKHKHKGKQ-KNKKPEKSSSSESSDSSDSQSDEE 910
            +K+K K K++ R +       K K   K KH   + KNK+  +S SSE +D+   +   +
Sbjct: 1098 HKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPK 1157

Query: 911  TA 912
             A
Sbjct: 1158 DA 1159



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 40/184 (21%), Positives = 78/184 (42%), Gaps = 27/184 (14%)

Query: 741 QAEGEGSRP-------SMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQD 793
           QA   G RP        ++L        SD+  S ++ E+  S +  +     + ++ +D
Sbjct: 279 QANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKD 338

Query: 794 TDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEK 853
           + + E+  +  +  P P     +    + + D+ EE    +             + +KE+
Sbjct: 339 SLICESKQILPSKTPLPS----ALDEYEFKDDDDEEINKMI---------DDRHILRKEQ 385

Query: 854 HKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEK--SSSSESSDSSDSQSDEET 911
            K+N+ +  A+K H   K++K  + K     K K +KP +   SS+ESSD    Q+ + +
Sbjct: 386 RKENEPE--AEKTHLFAKQEKAFYPK---SFKSKKQKPSRVLYSSTESSDEEALQNKKIS 440

Query: 912 ADVS 915
              S
Sbjct: 441 TSCS 444



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 62/276 (22%), Positives = 101/276 (36%), Gaps = 34/276 (12%)

Query: 654 PETASLPTTQASSEKVSQHRGPDKSRK--PSRWDTSKHEKKEDSISEFLSLARSKAEPPK 711
           P      +T++S E+  Q++    S    P   ++    KKE  +S             K
Sbjct: 418 PSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLK 477

Query: 712 QQSSPLVN---KEEEHAPELS--ANQTVNKDVDA----QAEGEGSRP-------SMDLFR 755
            Q+    N   K+E+   E +   N TVN  +D     + EG   +        S+ LF 
Sbjct: 478 NQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFH 537

Query: 756 AIFASSSDEKSSSSEDEQGDSEDDQA------GSGEANFQ-------SSQDTDLGETSSV 802
                S       SE +    + +        GS E + Q       +++   L E+SSV
Sbjct: 538 ISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSV 597

Query: 803 AHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHK 862
                    +    F ++  +    +       P F  N+  TL+  + +K  K   KHK
Sbjct: 598 KSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTF-ENSDCTLK--KMDKEGKTLKKHK 654

Query: 863 AKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSE 898
            K + R K++ KK+    K K K K+   E   S E
Sbjct: 655 LKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVE 690


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 51/244 (20%), Positives = 92/244 (37%), Gaps = 17/244 (6%)

Query: 675  PDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTV 734
            P+K++ P + +    EK +  + E       +    ++  SP+  KEEE   E+   +  
Sbjct: 782  PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV--KEEEKPQEVKVKEPP 839

Query: 735  NKDVDAQAEGEG-SRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQD 793
             K  + +A     +    D  +         K    E ++   E  +    EA  + ++D
Sbjct: 840  KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED 899

Query: 794  ---TDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQ 850
                   E  + A   V    +P     + K + D+ +   P  P           E  +
Sbjct: 900  KKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA----------EKKE 949

Query: 851  KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNK-KPEKSSSSESSDSSDSQSDE 909
                KK+  + KAKK   + K + K     K   K+ +K K EK+  S S+D  DS+  E
Sbjct: 950  AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009

Query: 910  ETAD 913
            +  +
Sbjct: 1010 KATE 1013



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 57/265 (21%), Positives = 113/265 (42%), Gaps = 16/265 (6%)

Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQS 714
           E A+ P  +A S    + + P +++ P + + +K   +  S  +  S A+ +A+ P +  
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEK-EEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565

Query: 715 SPLVNKEEEHAP-ELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQ 773
           SP   KEE  +P E+ + +        +A+      S +  ++      +E  S +E + 
Sbjct: 566 SP--EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS---PVKEEAKSPAEAKS 620

Query: 774 GDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPP-PSFPIQKMQIDEREEFGP 832
              E+ ++ +   + + ++     E  S   A  P  +E   P      ++ + +     
Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680

Query: 833 RLPPVFCPNARQTLEVPQKEKHK-----KNKDKHKAKKEHRRK---KEKKKKHRKHKHKG 884
           + P      + +  + P KE+ K     K+  K +AK   + K   KE+ K   K K   
Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740

Query: 885 KQKNKKPEKSSSSESSDSSDSQSDE 909
           K++ K PEK+ S E + + D +S E
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPE 765



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 59/283 (20%), Positives = 118/283 (41%), Gaps = 28/283 (9%)

Query: 654 PETASLPTTQ-------ASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSIS-------EF 699
           PE A  PT +       A S +  + + P+K++ P + +    EK +  +        + 
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694

Query: 700 LSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFA 759
            S  + +A+ P++  SP+  KEE  +PE  A   V ++  A+   +   P  +  ++   
Sbjct: 695 KSPVKEEAKSPEKAKSPV--KEEAKSPE-KAKSPVKEE--AKTPEKAKSPVKEEAKSPEK 749

Query: 760 SSSDEKSSSSEDEQGDSED---DQAGSGEANFQSSQDTDLGE-TSSVAHALVPAPQEPPP 815
           + S EK+ + + +  +++    ++A S    F     + + E   S   A  P  ++   
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809

Query: 816 SFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKK 875
                + +I ++EE    +     P   +  E P+K + +K     K +++   KKE+  
Sbjct: 810 P----EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP 865

Query: 876 KHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADVSPQE 918
           K    K K ++K K+P      ES   +  +  E+   V   E
Sbjct: 866 KKEAPKPKVEEK-KEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 64/277 (23%), Positives = 117/277 (42%), Gaps = 27/277 (9%)

Query: 655 ETASLPTTQASSEKV-----SQHRGPDKSRKPSRWDT-SKHEKKEDSISEFLSLARSKAE 708
           E A  P    S EK      ++ + P+K++ P++ +  S  E K     E  S A  K+ 
Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS- 580

Query: 709 PPKQQSSPLVNKEEEHAP-ELSANQTVNKDV--DAQAEGEGSRPSMDLFRAIFASSSDEK 765
            P++  SP   KEE  +P E  + +     V  +A++  E   P  +  ++     S EK
Sbjct: 581 -PEKAKSPA--KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637

Query: 766 SSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQID 825
           + S   E+  S + +A S E   + ++  +  ++   A A  P   + P       ++ +
Sbjct: 638 AKSPTKEEAKSPE-KAKSPEK--EEAKSPEKAKSPVKAEAKSPEKAKSP-------VKAE 687

Query: 826 EREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGK 885
            +     + P      + +  + P KE+ K  +      KE  +  EK K   K + K  
Sbjct: 688 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747

Query: 886 QKNKKPEKSSSSE-SSDSSDSQSDEET---ADVSPQE 918
           +K K PEK+ + +  S  + + + EE    AD  P++
Sbjct: 748 EKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK 784



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 3/79 (3%)

Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSS---SESS 900
           +T   P +E     K+     KE  +   + K   K + K   + K PEK+ S    E+ 
Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559

Query: 901 DSSDSQSDEETADVSPQEL 919
              +++S E+    SP E+
Sbjct: 560 SPPEAKSPEKEEAKSPAEV 578


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 16/208 (7%)

Query: 709 PPKQQSSPLVNKEEE--HAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKS 766
           P    S   V  EEE  H  +L  ++   K  + + +G+    S+        + SDE  
Sbjct: 716 PGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLP-------TESDEDI 768

Query: 767 SSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDE 826
           + ++     +E+    +  ++     D D  +        +  P       PIQK +  E
Sbjct: 769 APAQQVDIVTEEMPENALPSD---EDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTE 825

Query: 827 REEFGPRLPPVFCPNARQTLEVPQKEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKH--- 882
             +   +  P+    +++  +  +K K K ++K+K K K++ +  K KKKKHRK K    
Sbjct: 826 TSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERT 885

Query: 883 KGKQKNKKPEKSSSSESSDSSDSQSDEE 910
           KGK+K+KK    S   + +   + + EE
Sbjct: 886 KGKKKSKKQPPGSEEAAGEPVQNGAPEE 913



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 36/143 (25%), Positives = 66/143 (46%), Gaps = 15/143 (10%)

Query: 791 SQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQID-EREEFGPRLPPVFCPNARQTLEVP 849
           +Q  D+       +AL     +  P+ P + + ID ++        P+      +T + P
Sbjct: 771 AQQVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSP 830

Query: 850 QKE---------KHKKNKDKHKAK---KEHRRKKEKKK--KHRKHKHKGKQKNKKPEKSS 895
           +K+         K KK + KHK K   KE +++KEKKK  K +K KH+ +++ +   K  
Sbjct: 831 EKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKK 890

Query: 896 SSESSDSSDSQSDEETADVSPQE 918
           S +    S+  + E   + +P+E
Sbjct: 891 SKKQPPGSEEAAGEPVQNGAPEE 913



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 51/238 (21%), Positives = 98/238 (41%), Gaps = 44/238 (18%)

Query: 715 SPLVNKEEEHAPE---LSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSED 771
           +P+  K ++  P    L  +  +N+ + + +E E  RP     RA+F      +      
Sbjct: 605 NPVAPKAQKKVPVPEGLDLDAWINEPL-SDSESEDERP-----RAVFHEEEQRRPKHRPS 658

Query: 772 EQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFP----IQKMQIDER 827
           E    E++ A   EA  Q   +      SS      P+PQ+     P    I  +QID  
Sbjct: 659 EA--DEEELARRREARKQEQANNPFYIKSS------PSPQKRYQDTPGVEHIPVVQIDLS 710

Query: 828 EEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKK-HRKHKHKGKQ 886
                ++P +  P + Q +++ ++ +H++  +K K +K   ++KEK+KK  R+H     +
Sbjct: 711 VPL--KVPGL--PMSDQYVKLEEERRHRQKLEKDKRRK---KRKEKEKKGKRRHSSLPTE 763

Query: 887 KN--------------KKPEKSSSSESSDSSDSQSDEETADVSPQELLRRLKSLPLRR 930
            +              + PE +  S+  D  D        D+   + L   + LP+++
Sbjct: 764 SDEDIAPAQQVDIVTEEMPENALPSD-EDDKDPNDPYRALDIDLDKPLADSEKLPIQK 820


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 57/298 (19%), Positives = 112/298 (37%), Gaps = 54/298 (18%)

Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQS 714
           ET  LP + + +E++      D   +    D  KH   +  I E      S +E      
Sbjct: 124 ETRKLPGSDSENEELLNGHASDSENE----DVGKHPASDSEIEELQKSPASDSETEDALK 179

Query: 715 SPLVNKEEEHAPELSANQTVNKDV------DAQAEGEGSRPSMDLFRAIFASSSDEKSSS 768
             + + E E  P   A+ + N++       D+++E E  +P +         S  E    
Sbjct: 180 PQISDSESEEPPRHQASDSENEEPPKPRMSDSESE-ELPKPQV---------SDSESEEP 229

Query: 769 SEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQ------EPPP------- 815
              +  DSE+++      +   S+D    + S   +  +P P+      E PP       
Sbjct: 230 PRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDS 289

Query: 816 -SFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQK-----EKHKKNK----------- 858
            +  + K ++ + E  GP+  P             QK     +  ++NK           
Sbjct: 290 ENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSF 349

Query: 859 --DKHKAKKEHRRKKEKKKKHRKHKHKGKQKNK--KPEKSSSSESSDSSDSQSDEETA 912
             D H  +K+      ++++H+K K    +  K  + EK +  +++  SDS+ +E+ +
Sbjct: 350 HSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKAS 407



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 62/289 (21%), Positives = 102/289 (35%), Gaps = 70/289 (24%)

Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKE-------DSISEFLSLARSKA 707
           E+  LP  Q S  +         S +P R   S  E +E       DS SE         
Sbjct: 212 ESEELPKPQVSDSE---------SEEPPRHQASDSENEELPKPRISDSESE--------- 253

Query: 708 EPPKQQSSPLVNKE----------EEHAPELSANQTVNKDV------DAQAEGEGSRPSM 751
           +PP+ Q+S   N+E           E  P   A+ + N+++      D+++EG    P  
Sbjct: 254 DPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGP-- 311

Query: 752 DLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQ 811
                  AS S+ + +S   ++ +S+DD     +      Q+      S +      +  
Sbjct: 312 -------ASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSD 364

Query: 812 EPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKK 871
                   QKM  DE E+ G                  ++EK  K K    +  E   K 
Sbjct: 365 SEEEEHKKQKMDSDEDEKEG------------------EEEKVAKRKAAVLSDSEDEEKA 406

Query: 872 EKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSD--EETADVSPQE 918
             KK            +   +KS   E + +SDS+ +  +E +D   +E
Sbjct: 407 SAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEE 455



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 12/118 (10%)

Query: 678 SRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKD 737
           S K SR  +   +   D++S+         +  K++ +   + EEE   ELS  +   KD
Sbjct: 407 SAKKSRVVSDADDSDSDAVSD---------KSGKREKTIASDSEEEAGKELSDKKNEEKD 457

Query: 738 VDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTD 795
           +   ++ E      +L   IF  S DE+    E    + ED +   GE   + ++D+D
Sbjct: 458 LFG-SDSESGNEEENLIADIFGESGDEE--EEEFTGFNQEDLEEEKGETQVKEAEDSD 512


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 87/451 (19%), Positives = 176/451 (39%), Gaps = 31/451 (6%)

Query: 382 AATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAELLGET-PIQGSATSVLEFLSQ 440
           A   E+  +++  ++   +A   P   S H+   SK+++   ET P   ++ +V +  SQ
Sbjct: 139 ATNPESKQIVEEKTKRQNEADKTP-LKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQ 197

Query: 441 KDKERIKEMKQA-TDLKAAQLKARSLAQNAQSSRAQLSPAAAAGHCSWNMALGGGTATLK 499
           KDK+  K  K+  T+    +   +   + +++S   +S   +    + +  +  G +  +
Sbjct: 198 KDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDE 257

Query: 500 ASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMTEWERGRERDEFARAALLYA 559
           + NF  + ++  +    +  L + K  +KD  +     S  E E  ++  + ++      
Sbjct: 258 SINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKK----V 313

Query: 560 SSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLL 619
             +     +    K++ +S   E    ++     K+   K+K   K  +DT + +P+   
Sbjct: 314 KKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDK-KKDT-KKYPESTD 371

Query: 620 CKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPD--K 677
            +  +  D   DS  +       DK      +T        +T + SE  S+    D  K
Sbjct: 372 TESGDAKDARNDSRNLKKASKNDDKKKDAKKITF-------STDSESELESKESQKDEKK 424

Query: 678 SRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKD 737
            +K S+ D  K  K ++  ++        A+   +  S    K+E+   + S      KD
Sbjct: 425 DKKDSKTDNKKSVKNDEESTD--------ADSEPKGDSKKGKKDEKKGKKDSKKDDKKKD 476

Query: 738 VDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLG 797
               AE       ++L +      S EK  S +D + D+  D   S +A F  S  T   
Sbjct: 477 AKKNAESTEMESDLELKKD--KKHSKEKKGSKKDIKKDARKD-TESTDAEFDESSKTGFK 533

Query: 798 ETSSVAHALVPAPQEPPPSFPIQKMQIDERE 828
            ++ +  +      E     P  K +IDE +
Sbjct: 534 TSTKIKGS--DTESEESLYKPGAKKKIDESD 562



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 53/268 (19%), Positives = 103/268 (38%), Gaps = 19/268 (7%)

Query: 644 KYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLA 703
           KY+ +      + A   +   S +     +   K +K  + D  K + K+D+ S      
Sbjct: 279 KYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESG 338

Query: 704 RSKAE--PPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASS 761
            SK E    K+    L   +++   +     T  +  DA+     SR      +      
Sbjct: 339 DSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKK 398

Query: 762 SDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQK 821
             +K + S D + + E  ++   E   +    TD     SV +       +  P    +K
Sbjct: 399 DAKKITFSTDSESELESKESQKDEKKDKKDSKTD--NKKSVKNDEESTDADSEPKGDSKK 456

Query: 822 MQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHK 881
            + DE++              + + +  +K+  KKN +  + + +   KK+KK  H K K
Sbjct: 457 GKKDEKK------------GKKDSKKDDKKKDAKKNAESTEMESDLELKKDKK--HSKEK 502

Query: 882 HKGKQKNKKPEKSSSSESSDSSDSQSDE 909
            KG +K+ K +    +ES+D+   +S +
Sbjct: 503 -KGSKKDIKKDARKDTESTDAEFDESSK 529



 Score = 37.4 bits (85), Expect = 0.065
 Identities = 53/257 (20%), Positives = 108/257 (42%), Gaps = 47/257 (18%)

Query: 677 KSRKPSRWDTSKHEKKE-DSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVN 735
           K  K ++ DT K+ KK  D+ SE    A+  ++  K+     V K+++        + V 
Sbjct: 279 KYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKN----VKKDDK-------KKDVK 327

Query: 736 KDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTD 795
           KD ++     G              S DE+  + +D++   +DD+    +  +  S DT+
Sbjct: 328 KDTESTDAESGD-------------SKDERKDTKKDKKKLKKDDKKKDTK-KYPESTDTE 373

Query: 796 LGETSSVAHALVPAPQEPPPSFPIQKM-QIDEREEFGPRLPPVFCPNARQTLEVPQKEKH 854
            G+     +           S  ++K  + D++++   ++   F  ++   LE  + +K 
Sbjct: 374 SGDAKDARN----------DSRNLKKASKNDDKKKDAKKI--TFSTDSESELESKESQKD 421

Query: 855 KKNKDKHKAKKEHRRKKEKKKKH-------RKHKHKGKQKNKKPEKSSSSESSDSSDSQS 907
           +K KDK  +K ++++  +  ++        +    KGK+  KK +K S  +       ++
Sbjct: 422 EK-KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKN 480

Query: 908 DEETADVSPQELLRRLK 924
            E T   S  EL +  K
Sbjct: 481 AESTEMESDLELKKDKK 497


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 100/487 (20%), Positives = 186/487 (38%), Gaps = 71/487 (14%)

Query: 441 KDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAAAAGHCSWNMALGGGTATLKA 500
           K++ RI    ++ D     L++R   +  Q ++    P   +G+   + +    T   K 
Sbjct: 175 KERSRINSSGESGDESDEFLQSRKGQKKNQKNKP--GPNIESGNEDDDASFKIKTVAQK- 231

Query: 501 SNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMTEWERGRERDEFARAALLYAS 560
              K   K+ E++KR +E     K  +K+ LE        + E  R+ +E    + +   
Sbjct: 232 ---KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVD 288

Query: 561 SHSTLSSRF---THAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDK 617
           +    +S     T    EDD++  +  +D++   G+K+   K K  G          P K
Sbjct: 289 TGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKG----------PSK 338

Query: 618 LLCKRFNVPDPYPDSTLVGLP----RVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHR 673
              K            L  L     R KR++      L   E       +   EK  + +
Sbjct: 339 ATVKAMQ-------EALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK 391

Query: 674 GPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSA--N 731
             +K RK    +  K E K  + S+  + AR++A     Q+  +    ++  P+      
Sbjct: 392 QKEKERK----ERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYE 447

Query: 732 QTVNKDVDAQAEGEGSRPSMDLFRAI--FASSSDEKSSSSEDEQGDSEDDQAGSGEANFQ 789
               K +  Q E +    SM+L  A+        EK  +    + + E+D   +G  +++
Sbjct: 448 DKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWE 507

Query: 790 ---SSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTL 846
              S ++T+  E + V   +   P+E            +E EE                 
Sbjct: 508 AMASDEETEKVEGNKVHIEVKENPEE------------EEEEE----------------- 538

Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESS-DSSDS 905
           E  ++++  + +++ + + E     E+ +K    K  GK  +KKP K  SS+S  DS D 
Sbjct: 539 EEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDD 598

Query: 906 QSDEETA 912
           ++ EE A
Sbjct: 599 RTKEERA 605



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 61/316 (19%), Positives = 123/316 (38%), Gaps = 54/316 (17%)

Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSR--WDTSKHEKKEDSISEFLSLARSKAEPPK- 711
           ET ++  T+ + E+ +      K +K  +  +D +  E+ ED  S+    A+ K E    
Sbjct: 77  ETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSG 136

Query: 712 QQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFAS--SSDEKSSSS 769
                  NK  + A   +  Q  NK  D   E E +   +     I +S  S DE     
Sbjct: 137 SDDDDDFNKLPKKAKGKA--QKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFL 194

Query: 770 EDEQGDSEDDQAGSGEANFQSSQDTDLG-ETSSVAHALVPAPQEPPPSFPIQKMQIDERE 828
           +  +G  ++ +   G      ++D D   +  +VA       +        +K ++ + +
Sbjct: 195 QSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLK 254

Query: 829 EFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKE---------------------- 866
           E             ++ LE  +K++ K+ + + K ++E                      
Sbjct: 255 E-------------KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAET 301

Query: 867 ----------HRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS-SDSQSDEETADVS 915
                      ++KK+KKKK  + + K K+K K P K++     ++ +  + +EE     
Sbjct: 302 PTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKRE 361

Query: 916 PQELLRRLKSLPLRRQ 931
            +E ++RL+ L  +R+
Sbjct: 362 EEERIKRLEELEAKRK 377



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 55/288 (19%), Positives = 113/288 (39%), Gaps = 17/288 (5%)

Query: 649 NFLTLPETASLPTTQASSEKVSQHRGPDKSRK-PSRWDTSKHEKKEDSISEFLSLARSKA 707
           +F  LP+ A     +++ +        D S+K   R   +   +  D   EFL   + + 
Sbjct: 142 DFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQK 201

Query: 708 EPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSS 767
           +  K +  P +    E        +TV +    + E E  +   +  +       +E  +
Sbjct: 202 KNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELET 261

Query: 768 SSEDEQGDSEDDQAGSGEANFQSSQDTDLGET-SSVAHALVPAPQEPPPSFPIQKM---- 822
             +D Q   ++ Q    E   +S    D G   +S   A  P   E       +K     
Sbjct: 262 GKKD-QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKK 320

Query: 823 ---QIDEREEFGPRLPPVFCPNARQTL--EVPQKEKHKKNKDKHKAKK----EHRRKKEK 873
              + +E+E+   + P      A Q    ++ ++E+ +K +++ + K+    E +RK+E+
Sbjct: 321 KKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEE 380

Query: 874 KKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADVSPQELLR 921
           + +  K + K KQK K+ ++    E    + SQ +      +  +LL+
Sbjct: 381 RLEQEKRERK-KQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 60/288 (20%), Positives = 112/288 (38%), Gaps = 63/288 (21%)

Query: 670 SQHRGPDKSRKPSRWDTSKHEKKEDSIS---EFLSLARS--KAEPPKQQSSPLVNKEEEH 724
           ++ + P KS+   + +  K +  ED I    E LSL     KA+       P  N EEE 
Sbjct: 32  AKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEF 91

Query: 725 AP-------ELSANQTVNKDVDAQAEGEGSR------PSMDLFRAIFASSSDE------- 764
                    +    Q+ + +   + E + S+      P ++++     S SD+       
Sbjct: 92  TSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMY-----SGSDDDDDFNKL 146

Query: 765 ------KSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAP------QE 812
                 K+  S  +   SE+D+  S +   + S+    GE+   +   + +       Q+
Sbjct: 147 PKKAKGKAQKSNKKWDGSEEDEDNSKKIK-ERSRINSSGESGDESDEFLQSRKGQKKNQK 205

Query: 813 PPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHK-----KNKDKHKAKKEH 867
             P   I+    D+   F             +   V QK+  K     K +D+ KAK   
Sbjct: 206 NKPGPNIESGNEDDDASF-------------KIKTVAQKKAEKKERERKKRDEEKAKLRK 252

Query: 868 RRKKEKKKKHRKHKHKGKQKNKKPEKSS--SSESSDSSDSQSDEETAD 913
            ++KE+ +  +K + K K+  +K E+ +  S  + D+    + EE A+
Sbjct: 253 LKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE 300


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 64/297 (21%), Positives = 113/297 (38%), Gaps = 45/297 (15%)

Query: 655 ETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQ- 713
           + A+ PT ++SS + S     ++ +KP +          +    + S+    A PPK+  
Sbjct: 255 KAATTPTRKSSSSEDSSSDEEEEQKKPMK----------NKPGPYSSVPPPSAPPPKKSL 304

Query: 714 -SSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEK----SSS 768
            + P     E+  P + +++  + + D+ +E E   P+  +           K    SSS
Sbjct: 305 GTQPPKKAVEKQQP-VESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSS 363

Query: 769 SEDEQGDSEDDQAGSGEANF-QSSQDTDLGETSSVAHALVPAPQEP-----------PPS 816
              +   SEDD+A S  A   ++S +     T S A     AP++P             S
Sbjct: 364 DSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADS 423

Query: 817 FPIQKMQIDEREEFGPRLPPVFCPNA--RQTLEVPQKE----KHKKNKDKHKAKKEHRRK 870
              ++      EE   ++     P A  +  L +P K+        + D   +  E   +
Sbjct: 424 SSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEE 483

Query: 871 KEKKKKHRKHKHK----------GKQKNKKPEKSSSSESSDSSDSQSDEETADVSPQ 917
           K  K   +K   K             K  K E S+SS S DSS+ + ++     SP+
Sbjct: 484 KTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPR 540



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 68/257 (26%), Positives = 106/257 (41%), Gaps = 36/257 (14%)

Query: 678 SRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQ----- 732
           S + S  D  + +KK+         A++   PPK+  S   + +     E   NQ     
Sbjct: 129 SEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKIT 188

Query: 733 --TVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQS 790
             TV     A  +   + P +   +A  +SSS   SSSS+D    SE+++A +       
Sbjct: 189 PVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDD----SEEEKAAA------- 237

Query: 791 SQDTDLGETSSVAHALVPAPQEPP-PSFPIQKMQIDEREEF--------GP--RLPPVFC 839
           +    + +   VA A V A   P   S   +    DE EE         GP   +PP   
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSA 297

Query: 840 PNARQTL--EVPQK--EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKP--EK 893
           P  +++L  + P+K  EK +  +    +  E     E++KK        K   K P  +K
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357

Query: 894 SSSSESSDSSDSQSDEE 910
           ++ S SSDSSDS S E+
Sbjct: 358 AAES-SSDSSDSDSSED 373



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 53/260 (20%), Positives = 97/260 (37%), Gaps = 39/260 (15%)

Query: 660 PTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKED------SISEFLSLARSKAEPPKQQ 713
           P  +    +    + P K  K S  D+    + E        I+     A++KA P   +
Sbjct: 145 PVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPAR 204

Query: 714 SSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQ 773
           ++P +   +  +   S++ + + D D++ E   + P   + +    + +  K++++   +
Sbjct: 205 AAPKIANGKAASSSSSSSSSSSSD-DSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRK 263

Query: 774 GDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQE----PPPSFPIQKMQIDEREE 829
             S +D +   E   +       G  SSV     P P++     PP   ++K Q      
Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQ------ 317

Query: 830 FGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNK 889
                 PV              E  + + D+  +  E  +K   K    K   K     K
Sbjct: 318 ------PV--------------ESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357

Query: 890 KPEKSSSSESSDSSDSQSDE 909
             E  SSS+SSDS  S+ DE
Sbjct: 358 AAE--SSSDSSDSDSSEDDE 375



 Score = 37.4 bits (85), Expect = 0.065
 Identities = 52/251 (20%), Positives = 88/251 (35%), Gaps = 27/251 (10%)

Query: 687 SKHEKKEDSISEFLSLARSKAEPPK---QQSSPLVNKEEEHAPELSANQTVNKDVDAQ-- 741
           ++ +    S+ +  S     A+ P+   Q + P+  K ++ A    +  +  ++ + Q  
Sbjct: 41  TQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGP 100

Query: 742 --------AEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAG------SGEAN 787
                   A+  G  P     +A  +SSS+E S   ++E    +  Q G      + +A 
Sbjct: 101 PAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAP 160

Query: 788 FQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLE 847
            + ++ +D    SS      P   + P   P+      +      R  P    N +    
Sbjct: 161 PKKAKSSDSDSDSSSEDE--PPKNQKPKITPVTVKAQTKAPPKPARAAPKIA-NGKAASS 217

Query: 848 VPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQS 907
                    + D  + K     KK   KK    K   K       KSSSSE     DS S
Sbjct: 218 SSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE-----DSSS 272

Query: 908 DEETADVSPQE 918
           DEE     P +
Sbjct: 273 DEEEEQKKPMK 283


>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
          Length = 1303

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 4/73 (5%)

Query: 847 EVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHR-KHKHKGKQKNKKPEKSSSSESSDSSDS 905
           E  +KEK +K+      +K HRR K K+KK R K K + K++ K   K  +S S D SD 
Sbjct: 80  ERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDF 139

Query: 906 QSDEETADVSPQE 918
             D   +D SP E
Sbjct: 140 SDD---SDFSPSE 149


>gi|39932583 hypothetical protein LOC55051 isoform 1 [Homo sapiens]
          Length = 1164

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 5/101 (4%)

Query: 815 PSFPIQKM-QIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEK 873
           PSF +  +  + ++ E  P       P  R  L+    ++   NK   K K+  R+KK++
Sbjct: 29  PSFCVGSITSLSQQTEAAPAHVSEGLPLTRSHLKSESSDESDTNK---KLKQTSRKKKKE 85

Query: 874 KKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADV 914
           KKK RKH+H  K K +K   SSSS S   +DS+ D+ +  V
Sbjct: 86  KKKKRKHQHHKKTK-RKHGPSSSSRSETDTDSEKDKPSRGV 125



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 30/138 (21%), Positives = 54/138 (39%), Gaps = 14/138 (10%)

Query: 774 GDSEDDQAGSG--EANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFG 831
           G SE    GS   E ++ S+    +G  +S++     AP       P+ +  +       
Sbjct: 9   GLSEAPDGGSSRKELDWLSNPSFCVGSITSLSQQTEAAPAHVSEGLPLTRSHLKSESS-- 66

Query: 832 PRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKP 891
                    +   T +  ++   KK K+K K K++H+  K+ K+KH        + +   
Sbjct: 67  ---------DESDTNKKLKQTSRKKKKEKKK-KRKHQHHKKTKRKHGPSSSSRSETDTDS 116

Query: 892 EKSSSSESSDSSDSQSDE 909
           EK   S     S  +S+E
Sbjct: 117 EKDKPSRGVGGSKKESEE 134


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 50/251 (19%), Positives = 89/251 (35%), Gaps = 11/251 (4%)

Query: 665 SSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEH 724
           S  +   H      +K  R   S H+K+  S     S +RS +   ++ +   + KE+E 
Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKER 389

Query: 725 APELSANQTVNKDVDAQAEGE-GSRPSMDLFRAIFASSSDEKSSSSEDEQGDSED-DQAG 782
             E    +   ++ + + E E G     D  R        EK    E E+   +D D+  
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449

Query: 783 SGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNA 842
             E + +  ++ D  +            + PP S+   +       E   R        +
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR-------RS 502

Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKK-KHRKHKHKGKQKNKKPEKSSSSESSD 901
           R +   P+  K  K K         R KK+KK+ K R H  + +++ +      SS   D
Sbjct: 503 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 562

Query: 902 SSDSQSDEETA 912
             +      T+
Sbjct: 563 GKEKLEKNSTS 573



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 8/75 (10%)

Query: 850 QKEKHK-KNKDKHKAK-------KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
           +KEK + KNKD+ K +       KE  R++E++K+H K + K K+K +  EK    + S 
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465

Query: 902 SSDSQSDEETADVSP 916
             D +  ++    +P
Sbjct: 466 EIDEKRKKDKKSRTP 480



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 30/146 (20%), Positives = 63/146 (43%), Gaps = 6/146 (4%)

Query: 766 SSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQID 825
           S++ E E G S + + G   ++ +S        +SS +H+     Q    S    + +  
Sbjct: 290 SAAIEPESGKSNERKGGRSRSHTRSKS-----RSSSKSHSRRKRSQSKHRSRSHNRSRSR 344

Query: 826 EREEFGPRLPPVFCPNARQTLEVPQKEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKHKG 884
           +++    + P      +R+  +   +   + K KD  +  KE  R KEK ++  + + K 
Sbjct: 345 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 404

Query: 885 KQKNKKPEKSSSSESSDSSDSQSDEE 910
           ++K K+  K+   +     D + D+E
Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKE 430



 Score = 37.7 bits (86), Expect = 0.050
 Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 1/77 (1%)

Query: 843 RQTLEVPQKEKHKKNKDKHKAK-KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
           + T E  ++++  K KD+ K + +E  R+KEK++   K + K ++K+++ +K    E   
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437

Query: 902 SSDSQSDEETADVSPQE 918
             + + D +      Q+
Sbjct: 438 EKEHEKDRDKEKEKEQD 454



 Score = 37.0 bits (84), Expect = 0.086
 Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 851 KEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDE 909
           KE+ K + KDK K  +E  R+KE +K   K K K + K K+ EK  S E  +        
Sbjct: 419 KEREKDREKDKEK-DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS 477

Query: 910 ETADVSPQELLRRLKSLPLRRQ 931
            T   S     R   S   RR+
Sbjct: 478 RTPPRSYNASRRSRSSSRERRR 499



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 16/72 (22%), Positives = 35/72 (48%)

Query: 851 KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910
           KEK ++ + + + +K+  ++KEK++   K + K + K    ++    +S     S +   
Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 488

Query: 911 TADVSPQELLRR 922
            +  S +E  RR
Sbjct: 489 RSRSSSRERRRR 500


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 50/251 (19%), Positives = 89/251 (35%), Gaps = 11/251 (4%)

Query: 665 SSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEH 724
           S  +   H      +K  R   S H+K+  S     S +RS +   ++ +   + KE+E 
Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKER 273

Query: 725 APELSANQTVNKDVDAQAEGE-GSRPSMDLFRAIFASSSDEKSSSSEDEQGDSED-DQAG 782
             E    +   ++ + + E E G     D  R        EK    E E+   +D D+  
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333

Query: 783 SGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNA 842
             E + +  ++ D  +            + PP S+   +       E   R        +
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR-------RS 386

Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKK-KHRKHKHKGKQKNKKPEKSSSSESSD 901
           R +   P+  K  K K         R KK+KK+ K R H  + +++ +      SS   D
Sbjct: 387 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 446

Query: 902 SSDSQSDEETA 912
             +      T+
Sbjct: 447 GKEKLEKNSTS 457



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 8/75 (10%)

Query: 850 QKEKHK-KNKDKHKAK-------KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
           +KEK + KNKD+ K +       KE  R++E++K+H K + K K+K +  EK    + S 
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349

Query: 902 SSDSQSDEETADVSP 916
             D +  ++    +P
Sbjct: 350 EIDEKRKKDKKSRTP 364



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 30/146 (20%), Positives = 63/146 (43%), Gaps = 6/146 (4%)

Query: 766 SSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQID 825
           S++ E E G S + + G   ++ +S        +SS +H+     Q    S    + +  
Sbjct: 174 SAAIEPESGKSNERKGGRSRSHTRSKS-----RSSSKSHSRRKRSQSKHRSRSHNRSRSR 228

Query: 826 EREEFGPRLPPVFCPNARQTLEVPQKEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKHKG 884
           +++    + P      +R+  +   +   + K KD  +  KE  R KEK ++  + + K 
Sbjct: 229 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE 288

Query: 885 KQKNKKPEKSSSSESSDSSDSQSDEE 910
           ++K K+  K+   +     D + D+E
Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKE 314



 Score = 37.7 bits (86), Expect = 0.050
 Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 1/77 (1%)

Query: 843 RQTLEVPQKEKHKKNKDKHKAK-KEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
           + T E  ++++  K KD+ K + +E  R+KEK++   K + K ++K+++ +K    E   
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321

Query: 902 SSDSQSDEETADVSPQE 918
             + + D +      Q+
Sbjct: 322 EKEHEKDRDKEKEKEQD 338



 Score = 37.0 bits (84), Expect = 0.086
 Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 2/82 (2%)

Query: 851 KEKHK-KNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDE 909
           KE+ K + KDK K  +E  R+KE +K   K K K + K K+ EK  S E  +        
Sbjct: 303 KEREKDREKDKEK-DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS 361

Query: 910 ETADVSPQELLRRLKSLPLRRQ 931
            T   S     R   S   RR+
Sbjct: 362 RTPPRSYNASRRSRSSSRERRR 383



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 16/72 (22%), Positives = 35/72 (48%)

Query: 851 KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910
           KEK ++ + + + +K+  ++KEK++   K + K + K    ++    +S     S +   
Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASR 372

Query: 911 TADVSPQELLRR 922
            +  S +E  RR
Sbjct: 373 RSRSSSRERRRR 384


>gi|4507347 TBP-associated factor 2 [Homo sapiens]
          Length = 1199

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 56/180 (31%), Positives = 72/180 (40%), Gaps = 18/180 (10%)

Query: 742  AEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAG-SGEANFQSSQDT---DLG 797
            A    S P +  F+  F+SS DE+    E +     D QA  S   N      T      
Sbjct: 1021 ANNPSSHPQLVGFQNPFSSSQDEE----EIDMDTVHDSQAFISHHLNMLERPSTPGLSKY 1076

Query: 798  ETSSVAHALVPAPQEPPPSFPIQKMQID---EREEFGPRLPPV---FCPNARQTLEVPQK 851
              +S   AL+P       S P  K Q      R+  G    P+     P A   L V  K
Sbjct: 1077 RPASSRSALIPQHSAGCDSTPTTKPQWSLELARKGTGKEQAPLEMSMHPAASAPLSVFTK 1136

Query: 852  EKH-KKNKDKHKAKKEHRRKKEKKKKHR---KHKHKGKQKNKKPEKSSSSESSDSSDSQS 907
            E    K+ D H       +KK+KK KH+   KHKH  K+K+K+P   SS  S  S  S S
Sbjct: 1137 ESTASKHSDHHHHHHHEHKKKKKKHKHKHKHKHKHDSKEKDKEPFTFSSPASGRSIRSPS 1196


>gi|8923271 coiled-coil domain containing 49 [Homo sapiens]
          Length = 425

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 28/75 (37%), Positives = 42/75 (56%), Gaps = 7/75 (9%)

Query: 843 RQTLEVPQK-EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
           R+ L  P K +K K+       KKE ++KKEKKKKH+KHKH+    ++      SS   +
Sbjct: 151 REVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDR------SSSEDE 204

Query: 902 SSDSQSDEETADVSP 916
            S  +S ++ A+ SP
Sbjct: 205 HSAGRSQKKMANSSP 219



 Score = 33.5 bits (75), Expect = 0.95
 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 17/124 (13%)

Query: 813 PPPSFPIQKMQIDER---EEFGPRLPPVFCPNARQTL--------EVPQKEKHKKNKDKH 861
           P   +  +KM+  E     E G     +F P+   +L        E P     KK ++K 
Sbjct: 91  PIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKK 150

Query: 862 KAKKEHRRKKEKKKK------HRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADVS 915
           +    +  K +K K+       +K K K K+K KK +K     SS    S  DE +A  S
Sbjct: 151 REVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRS 210

Query: 916 PQEL 919
            +++
Sbjct: 211 QKKM 214


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 63/256 (24%), Positives = 98/256 (38%), Gaps = 31/256 (12%)

Query: 665 SSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEF-----LSLARSKAEPPKQQSSPLVN 719
           SSE+ ++   P K   P+    S+ E K  SI         +  R+ A P     S    
Sbjct: 470 SSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTG 529

Query: 720 KEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDD 779
            E+  +    A     K    QA    S P   +   + +   D+    SE   G     
Sbjct: 530 PEKRSSTRPPAEMEPGKG--EQASSSESDPEGPIAAQMLSFVMDDPDFESE---GSDTQR 584

Query: 780 QAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQI-DEREEFGPRLP--- 835
           +A         S  TD  E         PA   PPP  P+   ++ ++ + FG  L    
Sbjct: 585 RADDFPVRDDPSDVTDEDEG--------PAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAG 636

Query: 836 PVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHK--GKQ----KNK 889
           P       +  + P KEK KK K   K K+E  +  +KK KH+K K K  GK+    + +
Sbjct: 637 PKESSEEGKEGKTPSKEKKKKKK---KGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQ 693

Query: 890 KPEKSSSSESSDSSDS 905
           +P +S    ++D  ++
Sbjct: 694 RPPRSRERTAADELEA 709


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 55/240 (22%), Positives = 103/240 (42%), Gaps = 22/240 (9%)

Query: 669 VSQHRGPDKSRKPSRWD-------TSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKE 721
           +++ RGP +S  P+  D       T +  KK+    +  S A ++ E    ++     KE
Sbjct: 16  MARWRGPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENW---KKE 72

Query: 722 EEHAPE--LSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDE-----QG 774
            E + E  LS N++ +K    + E +  R       +  +SSSD  SSSS+ E     QG
Sbjct: 73  LEKSREKLLSGNESSSK----KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQG 128

Query: 775 DSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRL 834
                +      + QSS      E+         +  E      ++ +    ++ + P  
Sbjct: 129 KRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSY-PDD 187

Query: 835 PPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKS 894
            P+   ++ ++      +  KK + + + + + + KK+KKK+H+KH  K K+K+    KS
Sbjct: 188 KPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKS 247



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 32/114 (28%), Positives = 46/114 (40%), Gaps = 9/114 (7%)

Query: 797 GETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKK 856
           G T SV   +      P P++   K Q++ ++     L            E    E  KK
Sbjct: 21  GPTQSVGPTIQDYLNRPRPTWEEVKKQLENKKTGSKALAE---------FEEKMNENWKK 71

Query: 857 NKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910
             +K + K     +   KK+ RK K K K        SSS  SS SSDS+ +E+
Sbjct: 72  ELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEK 125



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 47/222 (21%), Positives = 77/222 (34%), Gaps = 60/222 (27%)

Query: 664 ASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEE 723
           +S ++  + +   KS + S   +S       S SE     + K    K+  S   ++   
Sbjct: 87  SSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146

Query: 724 HAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGS 783
           H  E  + ++V K   ++ E E  +    L +    S  D+K  SSE             
Sbjct: 147 HESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSE------------- 193

Query: 784 GEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNAR 843
                 SS ++D  E                     +K + +ERE+              
Sbjct: 194 ------SSSESDYEEDVQAK----------------KKRRCEEREQ-------------- 217

Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGK 885
                  KEK KK K     KK+H++  +KKKK     HK +
Sbjct: 218 ------AKEKVKKKK-----KKQHKKHSKKKKKKSGSSHKSR 248



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 852 EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSD 908
           E   ++K+  K KK+ + + EK+K  R    K K K+   +K  SSESS  SD + D
Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRK-KSYPDDKPLSSESSSESDYEED 203



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 17/52 (32%), Positives = 22/52 (42%)

Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSD 901
           + E   K   K K K +   +KEK  +    K K    + KP  S SS  SD
Sbjct: 148 ESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESD 199


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 1/81 (1%)

Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSS 903
           ++L   QK+K  +  D+ + KK+ + +K+KK +  + KHK K K+     SSSS SS + 
Sbjct: 214 KSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHK-KHKSSSSSSSSSSSSSSTE 272

Query: 904 DSQSDEETADVSPQELLRRLK 924
            S+S  E+   + ++ ++R K
Sbjct: 273 TSESSSESESNNKEKKIQRKK 293



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 35/89 (39%), Positives = 46/89 (51%), Gaps = 4/89 (4%)

Query: 847 EVPQKEKHKKNKDKHKAK---KEHRRKKEKKKKHRKHKHKGKQKNK-KPEKSSSSESSDS 902
           E P+ E  K    K K K   K  R +K+KKKK RK K   K ++K K  KSSSS SS S
Sbjct: 206 EDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSS 265

Query: 903 SDSQSDEETADVSPQELLRRLKSLPLRRQ 931
           S S S E +   S  E   + K +  +++
Sbjct: 266 SSSSSTETSESSSESESNNKEKKIQRKKR 294



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 10/79 (12%)

Query: 850 QKEKHKKNK----------DKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSES 899
           Q++K KKNK          +K K+KK    ++     H + K K K +  K E S     
Sbjct: 290 QRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSK 349

Query: 900 SDSSDSQSDEETADVSPQE 918
              SDS     T   SP++
Sbjct: 350 WSHSDSDKKSRTHKHSPEK 368



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 16/77 (20%)

Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKK----------------PEK 893
           +K+K KK K   +    H  +++ K+K R  KH+  +++ K                PEK
Sbjct: 309 EKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEK 368

Query: 894 SSSSESSDSSDSQSDEE 910
             S     SS S   EE
Sbjct: 369 RGSERKEGSSRSHGREE 385



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 15/70 (21%), Positives = 27/70 (38%)

Query: 851 KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910
           + KHKK+K    +          +      + +   K KK ++    ++  S  + SD E
Sbjct: 249 RSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSE 308

Query: 911 TADVSPQELL 920
             D S +  L
Sbjct: 309 EKDKSKKRKL 318



 Score = 30.4 bits (67), Expect = 8.0
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 12/74 (16%)

Query: 850 QKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHK------------HKGKQKNKKPEKSSSS 897
           +K+  +K + K+K    +    E+K K +K K             K K+K +  +  SS 
Sbjct: 286 EKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSR 345

Query: 898 ESSDSSDSQSDEET 911
           E S  S S SD+++
Sbjct: 346 EDSKWSHSDSDKKS 359


>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
          Length = 726

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 48/194 (24%), Positives = 80/194 (41%), Gaps = 42/194 (21%)

Query: 749 PSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVP 808
           P++    A   S   E S SSE+   DS      S     ++++  +L E     H  + 
Sbjct: 423 PALPAPAAPMVSKGAESSRSSEESSSDS----GSSDSEEERATRLAELQEQLKAVHEQLA 478

Query: 809 APQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHR 868
           A  + P + P +K                         E  +KEK KK+K+K K K + +
Sbjct: 479 ALSQAPVNKPKKKK------------------------EKKEKEKKKKDKEKEKEKHKVK 514

Query: 869 RKKEKKKKHRKHKHKGKQKNKKPEKSSSS------------ESSDSSDSQSDEETADVSP 916
            ++EKK K      + +QK    +K++S+            ++S S DS+ +EE   +S 
Sbjct: 515 AEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSY 574

Query: 917 QELLRRLKSLPLRR 930
            E  +R  SL + R
Sbjct: 575 DE--KRQLSLDINR 586



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 78/378 (20%), Positives = 140/378 (37%), Gaps = 65/378 (17%)

Query: 596 SAVKMKMFGKLTRDTFEWHPDKLL----CKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFL 651
           S VK KM G+   D   +  D  L    C ++N PD      +V + R  +D + +  F 
Sbjct: 359 STVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPD----HEVVAMARKLQDVFEM-RFA 413

Query: 652 TLP----ETASLPTTQA-----------SSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSI 696
            +P    E  +LP   A           SSE+ S   G   S +      ++ +++  ++
Sbjct: 414 KMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAV 473

Query: 697 SEFLS-LARSKAEPPKQQSSPLVNKE---------EEHAPELSANQTVNKDVDAQAEGEG 746
            E L+ L+++    PK++      ++         E+H  +    +       A+   + 
Sbjct: 474 HEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQK 533

Query: 747 SRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAG---SGEANFQSSQDTD------LG 797
             P+        A    +K         DSE+++ G   S +   Q S D +      LG
Sbjct: 534 KAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLG 593

Query: 798 ETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKN 857
               +  +  P+ ++  P     +++ID  E   P          +  L+  Q++    +
Sbjct: 594 RVVHIIQSREPSLRDSNPD----EIEIDF-ETLKPTTLRELERYVKSCLQKKQRKPFSAS 648

Query: 858 KDKHKAKKEHRRKKEKKK-----------------KHRKHKHKGKQKNKKPEKSSSSESS 900
             K  AK +    +EKKK                 K  + +  G   +  P + SSS SS
Sbjct: 649 GKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSS 708

Query: 901 DSSDSQSDEETADVSPQE 918
           +S  S S   ++D S  E
Sbjct: 709 ESGSSSSSGSSSDSSDSE 726


>gi|42718020 retinitis pigmentosa 9 [Homo sapiens]
          Length = 221

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 20/60 (33%), Positives = 38/60 (63%)

Query: 843 RQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDS 902
           +Q LE    ++ + +    + K++H++KK+K+K  ++ K K K+K +K + S S+E SDS
Sbjct: 161 KQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 4/52 (7%)

Query: 859 DKHKAKKEHRRKKEKKKK-HRKHKHKGKQKNKKPEKS---SSSESSDSSDSQ 906
           D+ ++       KEK KK  +K KHK ++K KK +K     SS+S++ SDS+
Sbjct: 170 DEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE 221


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 46/234 (19%), Positives = 90/234 (38%), Gaps = 15/234 (6%)

Query: 666 SEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHA 725
           S +  + +   K +   ++D SK  +    + +       + E  K  S    NK +   
Sbjct: 328 SNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVE 387

Query: 726 PELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGD--SEDDQAGS 783
                   ++ DVD   +   S        +    + +E  +S   E+G+  S+D++   
Sbjct: 388 GTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNK 447

Query: 784 GEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNAR 843
                  + D+  G+T SV HA V  P      +   K   D  +E       +     R
Sbjct: 448 QNKTKTQTSDSSEGKTKSVRHAYVHKP------YLYSKYYSDSDDE-------LTVEQRR 494

Query: 844 QTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSS 897
           Q++   ++E+  + +   +  +E R++K +K K  K K +G+      E S+ S
Sbjct: 495 QSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKS 548



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 113/621 (18%), Positives = 222/621 (35%), Gaps = 102/621 (16%)

Query: 379  PMVAATSENSHL-LQVLSESAGKATPDPGTHSKHQLNASKRAELLGETPIQGSATSVLEF 437
            P++A ++E  H    V   SAG+  P      K + +  +  E+ G    +G   S L  
Sbjct: 2398 PVLAVSTEEGHNGPSVHKPSAGQGHPSAVCAEKEEKHGKECPEI-GPFAGRGQKESTLHL 2456

Query: 438  LSQKDKERIKEMKQATDLK-----------AAQLKARSLAQNAQSSRAQLSPAAAAGHCS 486
            ++ ++K  +    Q  D             A+    R L  NA S      P   +G  +
Sbjct: 2457 INAEEKNVLLNSLQKEDKSPETGTAGGSSTASYSAGRGLEGNANSPAHLRGPEQTSGQTA 2516

Query: 487  WNMALG------GGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMT 540
             + ++         T  +KA +  P      +      FL   +QG +D L+     S T
Sbjct: 2517 KDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHS----FLPAEQQGSEDNLKT----STT 2568

Query: 541  EWERGRE------------------------------RDEFARAALLYASSHSTLSSRFT 570
            +   G+E                              +++++      AS+  T     T
Sbjct: 2569 KCITGQESKIAPSHTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQASAEKTGDDNST 2628

Query: 571  HAKEEDDSDQVEVPRDQEN--DVGDKQSAVK----MKMFGKLTRDTFEWHPDKLLCKRFN 624
                 ++ D +     +EN  D+G+++S +     +K+   L  + +    ++   +   
Sbjct: 2629 RKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKLKANLKMEAYVPSEEEKNGEILA 2688

Query: 625  VPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKS-RKPSR 683
             P+        G+  ++R+   V   L +  +      +  SE  S ++G   S RK + 
Sbjct: 2689 PPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSE--SYNKGEISSGRKDNA 2746

Query: 684  WDTSKHEKKED--SISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQ 741
               S H  + D   + E       +  P +++    ++ E+E  P+ + +   ++   AQ
Sbjct: 2747 EAISGHSVEADPKEVEE-----EERHMPKRKRKQHYLSSEDE--PDDNPDVLDSRIETAQ 2799

Query: 742  AEGEGSRP-------SMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDT 794
             +   + P       S DL      SS    ++S   E+ D       +GE   Q+  DT
Sbjct: 2800 RQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDT 2859

Query: 795  DLGETSSVAHALVPAPQEPPPSFPIQ---KMQIDEREEFGPRLPPVFCPNARQTLEVPQK 851
               +       ++   +  P  +P++   KM+ D + + G  +  V    +   L+V Q 
Sbjct: 2860 IKSQEEDQP-IIIKRKRGRPRKYPVETTLKMKDDSKTDTG--IVTVEQSPSSSKLKVMQT 2916

Query: 852  EKHKKN--------------KDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSS 897
            ++  K               ++K       R +K K+        +  +  +K +KS S 
Sbjct: 2917 DESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSD 2976

Query: 898  ESSDSSDSQSDEETADVSPQE 918
               D  + +SDEE  +    E
Sbjct: 2977 PVEDKKEQESDEEEEEEEEDE 2997



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 4/75 (5%)

Query: 851  KEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEE 910
            KEK+K +KD    + E  RK     K R  KH  K   KK E  S  +     DS  ++ 
Sbjct: 998  KEKYKSDKDSTSTRLE--RKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKA 1055

Query: 911  TADVSPQE--LLRRL 923
              + S  E  L RRL
Sbjct: 1056 RGNSSLMEKKLSRRL 1070



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 42/185 (22%), Positives = 76/185 (41%), Gaps = 32/185 (17%)

Query: 721 EEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQ 780
           +E  A   S   +  K  +  ++   S+P+ D        +S +K  +SED   D E   
Sbjct: 213 QEASAARASTETSNAKTSERASKKLPSQPTTD--------TSTDKERTSED-MADKEKST 263

Query: 781 AGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQI-----DEREEFGPRLP 835
           A SG    +++  ++  E S +     P P E   ++  +   +     D ++E      
Sbjct: 264 ADSGGEGLETAPKSE--EFSDL-----PCPVEEIKNYTKEHNNLILLNKDVQQE------ 310

Query: 836 PVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKH-RKHKHKGKQKNKKPEKS 894
                + ++     + EK   + +K + KKE + K EKK  H +K +   K K++K  K 
Sbjct: 311 ----SSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKE 366

Query: 895 SSSES 899
              ES
Sbjct: 367 KEVES 371



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 47/264 (17%), Positives = 100/264 (37%), Gaps = 53/264 (20%)

Query: 536  DPSMTEWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQ 595
            +P  T+ E  R+ +E  + +    S  ++ +SR    K+E  S +    + ++ND     
Sbjct: 2806 EPHDTKEENSRDLEELPKTS----SETNSTTSRVMEEKDEYSSSETTGEKPEQND----D 2857

Query: 596  SAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPE 655
              +K +          E     ++ ++   P  YP  T +   ++K D  +    +T+ +
Sbjct: 2858 DTIKSQ----------EEDQPIIIKRKRGRPRKYPVETTL---KMKDDSKTDTGIVTVEQ 2904

Query: 656  TASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSS 715
            + S     +S  KV Q    D+S K +     +    +D   + ++  R +   PK+   
Sbjct: 2905 SPS-----SSKLKVMQ---TDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKR--- 2953

Query: 716  PLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGD 775
                           + TV+ D       E S P     +++     D+K   S++E+ +
Sbjct: 2954 ---------------SLTVSDDA------ESSEPERKRQKSVSDPVEDKKEQESDEEEEE 2992

Query: 776  SEDDQAGSGEANFQSSQDTDLGET 799
             E+D+         +  +    +T
Sbjct: 2993 EEEDEPSGATTRSTTRSEAQRSKT 3016



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 10/75 (13%)

Query: 847 EVPQKEKHKKNKDKHKAKKE-------HRRKKEKKKKHRKHKHKGKQKNK---KPEKSSS 896
           +V Q+   +KNK   K +K+        R+K++K+K  +K  H  K ++    K EK + 
Sbjct: 306 DVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAK 365

Query: 897 SESSDSSDSQSDEET 911
            +  +S    S++ +
Sbjct: 366 EKEVESLKLPSEKNS 380


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,191,056
Number of Sequences: 37866
Number of extensions: 2100730
Number of successful extensions: 21024
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 366
Number of HSP's successfully gapped in prelim test: 495
Number of HSP's that attempted gapping in prelim test: 11808
Number of HSP's gapped (non-prelim): 5815
length of query: 931
length of database: 18,247,518
effective HSP length: 112
effective length of query: 819
effective length of database: 14,006,526
effective search space: 11471344794
effective search space used: 11471344794
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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