Guide to the Human Genome
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Search of human proteins with 113930754

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113930754 Src-like-adaptor isoform a [Homo sapiens]
         (276 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194328732 Src-like-adaptor isoform c [Homo sapiens]                566   e-162
gi|194328725 Src-like-adaptor isoform b [Homo sapiens]                566   e-162
gi|113930754 Src-like-adaptor isoform a [Homo sapiens]                566   e-162
gi|14149916 Src-like-adaptor 2 isoform a [Homo sapiens]               186   1e-47
gi|28416424 Src-like-adaptor 2 isoform b [Homo sapiens]               142   2e-34
gi|33469982 B lymphoid tyrosine kinase [Homo sapiens]                 142   3e-34
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]     137   8e-33
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...   136   2e-32
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs...   132   3e-31
gi|112789546 lymphocyte-specific protein tyrosine kinase precurs...   132   3e-31
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...   132   3e-31
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]              126   2e-29
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]       124   1e-28
gi|112382244 proto-oncogene tyrosine-protein kinase FGR [Homo sa...   122   4e-28
gi|112382241 proto-oncogene tyrosine-protein kinase FGR [Homo sa...   122   4e-28
gi|4885235 proto-oncogene tyrosine-protein kinase FGR [Homo sapi...   122   4e-28
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]      119   3e-27
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...   111   8e-25
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...   111   8e-25
gi|4503787 fyn-related kinase [Homo sapiens]                          109   2e-24
gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]      105   3e-23
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a...    75   6e-14
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b...    75   6e-14
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]              74   1e-13
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]                74   1e-13
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]              74   1e-13
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]              74   1e-13
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]              74   1e-13
gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]                 68   8e-12
gi|4557377 Bruton agammaglobulinemia tyrosine kinase [Homo sapiens]    68   1e-11

>gi|194328732 Src-like-adaptor isoform c [Homo sapiens]
          Length = 316

 Score =  566 bits (1458), Expect = e-162
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK 60
           MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK
Sbjct: 41  MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK 100

Query: 61  AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY 120
           AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY
Sbjct: 101 AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY 160

Query: 121 SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST 180
           SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST
Sbjct: 161 SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST 220

Query: 181 AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT 240
           AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT
Sbjct: 221 AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT 280

Query: 241 SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 276
           SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED
Sbjct: 281 SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 316


>gi|194328725 Src-like-adaptor isoform b [Homo sapiens]
          Length = 293

 Score =  566 bits (1458), Expect = e-162
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK 60
           MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK
Sbjct: 18  MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK 77

Query: 61  AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY 120
           AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY
Sbjct: 78  AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY 137

Query: 121 SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST 180
           SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST
Sbjct: 138 SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST 197

Query: 181 AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT 240
           AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT
Sbjct: 198 AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT 257

Query: 241 SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 276
           SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED
Sbjct: 258 SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 293


>gi|113930754 Src-like-adaptor isoform a [Homo sapiens]
          Length = 276

 Score =  566 bits (1458), Expect = e-162
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK 60
           MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK
Sbjct: 1   MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK 60

Query: 61  AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY 120
           AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY
Sbjct: 61  AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY 120

Query: 121 SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST 180
           SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST
Sbjct: 121 SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST 180

Query: 181 AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT 240
           AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT
Sbjct: 181 AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT 240

Query: 241 SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 276
           SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED
Sbjct: 241 SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED 276


>gi|14149916 Src-like-adaptor 2 isoform a [Homo sapiens]
          Length = 261

 Score =  186 bits (473), Expect = 1e-47
 Identities = 97/219 (44%), Positives = 136/219 (62%), Gaps = 10/219 (4%)

Query: 30  LSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGL 89
           L  +P+   +    R GE L ++S++G WW  +S  +GRE  IP + VA+V HGWL+EGL
Sbjct: 40  LGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGL 99

Query: 90  GRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVR------HRQVKHYRIFRLPNNWYY 143
            R+KAEELL LP    G+F+IRES+T++G YSLSVR        +++HYRI  L N W Y
Sbjct: 100 SREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLY 159

Query: 144 ISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRR 203
           ISPRLTF  L+ LV+HYSE+AD +CC+L  PC+ Q       +    PVT+++  ++W+ 
Sbjct: 160 ISPRLTFPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKE 219

Query: 204 VSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSE 242
           +       E        +ESL S GLRES++ Y+SL  E
Sbjct: 220 LDSSLLFSEAATG----EESLLSEGLRESLSFYISLNDE 254


>gi|28416424 Src-like-adaptor 2 isoform b [Homo sapiens]
          Length = 210

 Score =  142 bits (359), Expect = 2e-34
 Identities = 71/139 (51%), Positives = 94/139 (67%), Gaps = 6/139 (4%)

Query: 30  LSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGL 89
           L  +P+   +    R GE L ++S++G WW  +S  +GRE  IP + VA+V HGWL+EGL
Sbjct: 40  LGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGL 99

Query: 90  GRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVR------HRQVKHYRIFRLPNNWYY 143
            R+KAEELL LP    G+F+IRES+T++G YSLSVR        +++HYRI  L N W Y
Sbjct: 100 SREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLY 159

Query: 144 ISPRLTFQCLEDLVNHYSE 162
           ISPRLTF  L+ LV+HYSE
Sbjct: 160 ISPRLTFPSLQALVDHYSE 178


>gi|33469982 B lymphoid tyrosine kinase [Homo sapiens]
          Length = 505

 Score =  142 bits (358), Expect = 3e-34
 Identities = 83/180 (46%), Positives = 101/180 (56%), Gaps = 11/180 (6%)

Query: 15  PLPNPEGLDSD--FLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYI 72
           P P  E LD D  F+  L DY + +       +GEKL+V+   G WW A SL TGRE Y+
Sbjct: 49  PPPPDEHLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLKGTGDWWLARSLVTGREGYV 108

Query: 73  PGICVARV----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH-- 126
           P   VARV       W F   GR +AE  L  P  K GSF+IRESET KG +SLSV+   
Sbjct: 109 PSNFVARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVT 168

Query: 127 ---RQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAP 183
                +KHY+I  L    YYISPR+TF  L+ LV HYS+  DGLC  LT PC+  +   P
Sbjct: 169 TQGELIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTLPCVRPAPQNP 228


>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
          Length = 526

 Score =  137 bits (346), Expect = 8e-33
 Identities = 77/173 (44%), Positives = 102/173 (58%), Gaps = 10/173 (5%)

Query: 21  GLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARV 80
           G +   +  L DY +       F++G+++ V+ + G WWKA SL+T +E YIP   VARV
Sbjct: 77  GSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSLATRKEGYIPSNYVARV 136

Query: 81  ----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH---RQ---VK 130
                  W F+G+ R  AE  L  P   +GSFMIR+SET KG YSLSVR    RQ   VK
Sbjct: 137 DSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVK 196

Query: 131 HYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAP 183
           HY+I  L N  +YISPR TF  L++LV+HY +  DGLC  L+ PC++     P
Sbjct: 197 HYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKP 249


>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform B [Homo sapiens]
          Length = 491

 Score =  136 bits (342), Expect = 2e-32
 Identities = 80/201 (39%), Positives = 109/201 (54%), Gaps = 22/201 (10%)

Query: 2   GNSMKSTPAPAERPLP-------NPEGLDSDFLAVLSDYPSPDISPP--IFRRGEKLRVI 52
           G  +K+ P P  + LP       +PE    D +  L  YP   I P    F++GEK++V+
Sbjct: 16  GVDLKTQPVPESQLLPGQRFQTKDPEE-QGDIVVAL--YPYDGIHPDDLSFKKGEKMKVL 72

Query: 53  SDEGGWWKAISLSTGRESYIPGICVARVY----HGWLFEGLGRDKAEELLQLPDTKVGSF 108
            + G WWKA SL T +E +IP   VA++       W F+ + R  AE  L  P    G+F
Sbjct: 73  EEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAERQLLAPGNSAGAF 132

Query: 109 MIRESETKKGFYSLSVRHRQ------VKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSE 162
           +IRESET KG +SLSVR         +KHY+I  L N  YYISPR+TF C+ D++ HY +
Sbjct: 133 LIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQK 192

Query: 163 VADGLCCVLTTPCLTQSTAAP 183
            ADGLC  L   C++     P
Sbjct: 193 QADGLCRRLEKACISPKPQKP 213


>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  132 bits (333), Expect = 3e-31
 Identities = 76/192 (39%), Positives = 100/192 (52%), Gaps = 10/192 (5%)

Query: 2   GNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWKA 61
           G+ ++      E   P    L  + +  L  Y         F +GE+LR++   G WWKA
Sbjct: 41  GSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKA 100

Query: 62  ISLSTGRESYIPGICVARVY----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKK 117
            SL+TG+E +IP   VA+        W F+ L R  AE  L  P    GSF+IRESE+  
Sbjct: 101 QSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTA 160

Query: 118 GFYSLSVRH------RQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVL 171
           G +SLSVR         VKHY+I  L N  +YISPR+TF  L +LV HY+  +DGLC  L
Sbjct: 161 GSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRL 220

Query: 172 TTPCLTQSTAAP 183
           + PC TQ    P
Sbjct: 221 SRPCQTQKPQKP 232


>gi|112789546 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  132 bits (333), Expect = 3e-31
 Identities = 76/192 (39%), Positives = 100/192 (52%), Gaps = 10/192 (5%)

Query: 2   GNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWKA 61
           G+ ++      E   P    L  + +  L  Y         F +GE+LR++   G WWKA
Sbjct: 41  GSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKA 100

Query: 62  ISLSTGRESYIPGICVARVY----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKK 117
            SL+TG+E +IP   VA+        W F+ L R  AE  L  P    GSF+IRESE+  
Sbjct: 101 QSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTA 160

Query: 118 GFYSLSVRH------RQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVL 171
           G +SLSVR         VKHY+I  L N  +YISPR+TF  L +LV HY+  +DGLC  L
Sbjct: 161 GSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRL 220

Query: 172 TTPCLTQSTAAP 183
           + PC TQ    P
Sbjct: 221 SRPCQTQKPQKP 232


>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform A [Homo sapiens]
          Length = 512

 Score =  132 bits (333), Expect = 3e-31
 Identities = 71/167 (42%), Positives = 97/167 (58%), Gaps = 12/167 (7%)

Query: 29  VLSDYPSPDISPP--IFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARV----YH 82
           V++ YP   I P    F++GEK++V+ + G WWKA SL T +E +IP   VA++      
Sbjct: 68  VVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETE 127

Query: 83  GWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQ------VKHYRIFR 136
            W F+ + R  AE  L  P    G+F+IRESET KG +SLSVR         +KHY+I  
Sbjct: 128 EWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRS 187

Query: 137 LPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQSTAAP 183
           L N  YYISPR+TF C+ D++ HY + ADGLC  L   C++     P
Sbjct: 188 LDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKP 234


>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
          Length = 543

 Score =  126 bits (316), Expect = 2e-29
 Identities = 75/176 (42%), Positives = 97/176 (55%), Gaps = 13/176 (7%)

Query: 15  PLPNPEGLDSD--FLAVLSDYPSPDISPPIFRRGEKLRVISD-EGGWWKAISLSTGRESY 71
           P   P GL         L DY +       F++GE+ ++I++ EG WW+A S++TG+  Y
Sbjct: 82  PSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGY 141

Query: 72  IPGICVARV----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH- 126
           IP   VA         W F  +GR  AE LL  P  + G F++RESET KG YSLS+R  
Sbjct: 142 IPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW 201

Query: 127 -----RQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLT 177
                  VKHY+I +L N  YYI+ R  F  L+ LV HY+E ADGLC  LTT C T
Sbjct: 202 DEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPT 257


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score =  124 bits (310), Expect = 1e-28
 Identities = 74/166 (44%), Positives = 89/166 (53%), Gaps = 11/166 (6%)

Query: 21  GLDSDFLAVLSDYPSPDISPPIFRRGEKLRVI-SDEGGWWKAISLSTGRESYIPGICVAR 79
           G        L DY +       F +GEK +++ S EG WW+A SL+TG   YIP   VA 
Sbjct: 81  GTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140

Query: 80  V----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH------RQV 129
           V       W F  LGR  AE  L       G+F+IRESET KG YSLS+R         V
Sbjct: 141 VDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHV 200

Query: 130 KHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPC 175
           KHY+I +L N  YYI+ R  F+ L+ LV HYSE A GLCC L  PC
Sbjct: 201 KHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPC 246


>gi|112382244 proto-oncogene tyrosine-protein kinase FGR [Homo
           sapiens]
          Length = 529

 Score =  122 bits (305), Expect = 4e-28
 Identities = 76/193 (39%), Positives = 101/193 (52%), Gaps = 16/193 (8%)

Query: 21  GLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISD-EGGWWKAISLSTGRESYIPGICVAR 79
           G+       L DY +       F +GEK  ++++ EG WW+A SLS+G+   IP   VA 
Sbjct: 76  GIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAP 135

Query: 80  V----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH------RQV 129
           V       W F  +GR  AE  L  P    G+F+IRESET KG YSLS+R         V
Sbjct: 136 VDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHV 195

Query: 130 KHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCL-----TQSTAAPA 184
           KHY+I +L    YYI+ R+ F  +++LV HY EV DGLC +L  PC      T   A  A
Sbjct: 196 KHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDA 255

Query: 185 VRASSSPVTLRQK 197
              S S +TL ++
Sbjct: 256 WEISRSSITLERR 268


>gi|112382241 proto-oncogene tyrosine-protein kinase FGR [Homo
           sapiens]
          Length = 529

 Score =  122 bits (305), Expect = 4e-28
 Identities = 76/193 (39%), Positives = 101/193 (52%), Gaps = 16/193 (8%)

Query: 21  GLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISD-EGGWWKAISLSTGRESYIPGICVAR 79
           G+       L DY +       F +GEK  ++++ EG WW+A SLS+G+   IP   VA 
Sbjct: 76  GIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAP 135

Query: 80  V----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH------RQV 129
           V       W F  +GR  AE  L  P    G+F+IRESET KG YSLS+R         V
Sbjct: 136 VDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHV 195

Query: 130 KHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCL-----TQSTAAPA 184
           KHY+I +L    YYI+ R+ F  +++LV HY EV DGLC +L  PC      T   A  A
Sbjct: 196 KHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDA 255

Query: 185 VRASSSPVTLRQK 197
              S S +TL ++
Sbjct: 256 WEISRSSITLERR 268


>gi|4885235 proto-oncogene tyrosine-protein kinase FGR [Homo
           sapiens]
          Length = 529

 Score =  122 bits (305), Expect = 4e-28
 Identities = 76/193 (39%), Positives = 101/193 (52%), Gaps = 16/193 (8%)

Query: 21  GLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISD-EGGWWKAISLSTGRESYIPGICVAR 79
           G+       L DY +       F +GEK  ++++ EG WW+A SLS+G+   IP   VA 
Sbjct: 76  GIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAP 135

Query: 80  V----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH------RQV 129
           V       W F  +GR  AE  L  P    G+F+IRESET KG YSLS+R         V
Sbjct: 136 VDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHV 195

Query: 130 KHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCL-----TQSTAAPA 184
           KHY+I +L    YYI+ R+ F  +++LV HY EV DGLC +L  PC      T   A  A
Sbjct: 196 KHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDA 255

Query: 185 VRASSSPVTLRQK 197
              S S +TL ++
Sbjct: 256 WEISRSSITLERR 268


>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
          Length = 534

 Score =  119 bits (298), Expect = 3e-27
 Identities = 74/174 (42%), Positives = 93/174 (53%), Gaps = 14/174 (8%)

Query: 21  GLDSDFLAVLSDYPSPDISPPIFRRGEKLRVI-SDEGGWWKAISLSTGRESYIPGICVAR 79
           G        L DY +       F +GEK +++ S EG WW+A SL+TG   YIP   VA 
Sbjct: 81  GTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140

Query: 80  V----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH------RQV 129
           V       W F  LGR  AE  L       G+F+IRESET KG YSLS+R         V
Sbjct: 141 VDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHV 200

Query: 130 KHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLC---CVLTTPCLTQST 180
           KHY+I +L N  YYI+ R  F+ L+ LV HYSE ADGLC    V+ + C  Q++
Sbjct: 201 KHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIASSCTPQTS 254


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  111 bits (277), Expect = 8e-25
 Identities = 73/186 (39%), Positives = 104/186 (55%), Gaps = 14/186 (7%)

Query: 3   NSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISD-EGGWWKA 61
           NS  +  +P +R  P   G+ +     L DY S   +   F++GE+L+++++ EG WW A
Sbjct: 68  NSSDTVTSP-QRAGPLAGGVTT--FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLA 124

Query: 62  ISLSTGRESYIPGICVARV----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKK 117
            SLSTG+  YIP   VA         W F  + R ++E LL   +   G+F++RESET K
Sbjct: 125 HSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTK 184

Query: 118 GFYSLSV------RHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVL 171
           G Y LSV      +   VKHY+I +L +  +YI+ R  F  L+ LV +YS+ ADGLC  L
Sbjct: 185 GAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRL 244

Query: 172 TTPCLT 177
           TT C T
Sbjct: 245 TTVCPT 250


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  111 bits (277), Expect = 8e-25
 Identities = 73/186 (39%), Positives = 104/186 (55%), Gaps = 14/186 (7%)

Query: 3   NSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISD-EGGWWKA 61
           NS  +  +P +R  P   G+ +     L DY S   +   F++GE+L+++++ EG WW A
Sbjct: 68  NSSDTVTSP-QRAGPLAGGVTT--FVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLA 124

Query: 62  ISLSTGRESYIPGICVARV----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKK 117
            SLSTG+  YIP   VA         W F  + R ++E LL   +   G+F++RESET K
Sbjct: 125 HSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTK 184

Query: 118 GFYSLSV------RHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVL 171
           G Y LSV      +   VKHY+I +L +  +YI+ R  F  L+ LV +YS+ ADGLC  L
Sbjct: 185 GAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRL 244

Query: 172 TTPCLT 177
           TT C T
Sbjct: 245 TTVCPT 250


>gi|4503787 fyn-related kinase [Homo sapiens]
          Length = 505

 Score =  109 bits (273), Expect = 2e-24
 Identities = 79/220 (35%), Positives = 103/220 (46%), Gaps = 28/220 (12%)

Query: 7   STPAPAERPLPNPEGLDSD-------FLAVLSDYPSPDISPPIFRRGEKLRVISD-EGGW 58
           ST A     + NP  L S        +   L DY +       FR G+KL+V+     GW
Sbjct: 20  STEADKSTVIENPGALCSPQSQRHGHYFVALFDYQARTAEDLSFRAGDKLQVLDTLHEGW 79

Query: 59  WKAISLSTGRES-------YIPGICVAR----VYHGWLFEGLGRDKAEELLQLPDTKVGS 107
           W A  L   R+        YIP   VA         W F  +GR  AE+ L   + K GS
Sbjct: 80  WFARHLEKRRDGSSQQLQGYIPSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGS 139

Query: 108 FMIRESETKKGFYSLSVRHRQV-KHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADG 166
           F+IRESE++KG +SLSV    V KHYRI RL    ++++ R  F  L + V+HY++ +DG
Sbjct: 140 FLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDG 199

Query: 167 LCCVLTTPCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSR 206
           LC  L  PCL     A        P  L  KTVD   + R
Sbjct: 200 LCVKLGKPCLKIQVPA--------PFDLSYKTVDQWEIDR 231


>gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]
          Length = 482

 Score =  105 bits (263), Expect = 3e-23
 Identities = 66/157 (42%), Positives = 82/157 (52%), Gaps = 11/157 (7%)

Query: 21  GLDSDFLAVLSDYPSPDISPPIFRRGEKLRVI-SDEGGWWKAISLSTGRESYIPGICVAR 79
           G        L DY +       F +GEK +++ S EG WW+A SL+TG   YIP   VA 
Sbjct: 81  GTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAP 140

Query: 80  V----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRH------RQV 129
           V       W F  LGR  AE  L       G+F+IRESET KG YSLS+R         V
Sbjct: 141 VDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHV 200

Query: 130 KHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADG 166
           KHY+I +L N  YYI+ R  F+ L+ LV HYS   +G
Sbjct: 201 KHYKIRKLDNGGYYITTRAQFETLQQLVQHYSGTWNG 237


>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
           [Homo sapiens]
          Length = 1130

 Score = 75.1 bits (183), Expect = 6e-14
 Identities = 55/168 (32%), Positives = 80/168 (47%), Gaps = 9/168 (5%)

Query: 13  ERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVIS-DEGGWWKAISLSTGRESY 71
           E  L  P   D +    L D+ +   +     +GEKLRV+  +  G W       G + +
Sbjct: 52  ENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNG-QGW 110

Query: 72  IPGICVARVY----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHR 127
           +P   +  V     H W    + R+ AE LL       GSF++RESE+  G  S+S+R+ 
Sbjct: 111 VPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLRYE 168

Query: 128 -QVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTP 174
            +V HYRI    +   Y+S    F  L +LV+H+S VADGL   L  P
Sbjct: 169 GRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYP 216


>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
           [Homo sapiens]
          Length = 1149

 Score = 75.1 bits (183), Expect = 6e-14
 Identities = 55/168 (32%), Positives = 80/168 (47%), Gaps = 9/168 (5%)

Query: 13  ERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVIS-DEGGWWKAISLSTGRESY 71
           E  L  P   D +    L D+ +   +     +GEKLRV+  +  G W       G + +
Sbjct: 71  ENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNG-QGW 129

Query: 72  IPGICVARVY----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHR 127
           +P   +  V     H W    + R+ AE LL       GSF++RESE+  G  S+S+R+ 
Sbjct: 130 VPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLRYE 187

Query: 128 -QVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTP 174
            +V HYRI    +   Y+S    F  L +LV+H+S VADGL   L  P
Sbjct: 188 GRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYP 235


>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
          Length = 1167

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 51/158 (32%), Positives = 78/158 (49%), Gaps = 9/158 (5%)

Query: 23  DSDFLAVLSDYPSPDISPPIFRRGEKLRVIS-DEGGWWKAISLSTGRESYIPGICVARVY 81
           D +    L D+ +   +     +GEKLRV+  ++ G W  +    G + ++P   +  V 
Sbjct: 93  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNG-QGWVPSNYITPVN 151

Query: 82  ----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHR-QVKHYRIFR 136
               H W    + R  AE LL       GSF++RESE+  G  S+S+R+  +V HYRI  
Sbjct: 152 SLEKHSWYHGPVSRSAAEYLLS--SLINGSFLVRESESSPGQLSISLRYEGRVYHYRINT 209

Query: 137 LPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTP 174
             +   Y++    F  L +LV+H+S VADGL   L  P
Sbjct: 210 TADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP 247


>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
          Length = 1182

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 51/158 (32%), Positives = 78/158 (49%), Gaps = 9/158 (5%)

Query: 23  DSDFLAVLSDYPSPDISPPIFRRGEKLRVIS-DEGGWWKAISLSTGRESYIPGICVARVY 81
           D +    L D+ +   +     +GEKLRV+  ++ G W  +    G + ++P   +  V 
Sbjct: 108 DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNG-QGWVPSNYITPVN 166

Query: 82  ----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHR-QVKHYRIFR 136
               H W    + R  AE LL       GSF++RESE+  G  S+S+R+  +V HYRI  
Sbjct: 167 SLEKHSWYHGPVSRSAAEYLLS--SLINGSFLVRESESSPGQLSISLRYEGRVYHYRINT 224

Query: 137 LPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTP 174
             +   Y++    F  L +LV+H+S VADGL   L  P
Sbjct: 225 TADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP 262


>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
          Length = 542

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 51/158 (32%), Positives = 78/158 (49%), Gaps = 9/158 (5%)

Query: 23  DSDFLAVLSDYPSPDISPPIFRRGEKLRVIS-DEGGWWKAISLSTGRESYIPGICVARVY 81
           D +    L D+ +   +     +GEKLRV+  ++ G W  +    G + ++P   +  V 
Sbjct: 87  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNG-QGWVPSNYITPVN 145

Query: 82  ----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHR-QVKHYRIFR 136
               H W    + R  AE LL       GSF++RESE+  G  S+S+R+  +V HYRI  
Sbjct: 146 SLEKHSWYHGPVSRSAAEYLLS--SLINGSFLVRESESSPGQLSISLRYEGRVYHYRINT 203

Query: 137 LPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTP 174
             +   Y++    F  L +LV+H+S VADGL   L  P
Sbjct: 204 TADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP 241


>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
          Length = 1064

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 51/158 (32%), Positives = 78/158 (49%), Gaps = 9/158 (5%)

Query: 23  DSDFLAVLSDYPSPDISPPIFRRGEKLRVIS-DEGGWWKAISLSTGRESYIPGICVARVY 81
           D +    L D+ +   +     +GEKLRV+  ++ G W  +    G + ++P   +  V 
Sbjct: 93  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNG-QGWVPSNYITPVN 151

Query: 82  ----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHR-QVKHYRIFR 136
               H W    + R  AE LL       GSF++RESE+  G  S+S+R+  +V HYRI  
Sbjct: 152 SLEKHSWYHGPVSRSAAEYLLS--SLINGSFLVRESESSPGQLSISLRYEGRVYHYRINT 209

Query: 137 LPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTP 174
             +   Y++    F  L +LV+H+S VADGL   L  P
Sbjct: 210 TADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP 247


>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
          Length = 1146

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 51/158 (32%), Positives = 78/158 (49%), Gaps = 9/158 (5%)

Query: 23  DSDFLAVLSDYPSPDISPPIFRRGEKLRVIS-DEGGWWKAISLSTGRESYIPGICVARVY 81
           D +    L D+ +   +     +GEKLRV+  ++ G W  +    G + ++P   +  V 
Sbjct: 72  DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNG-QGWVPSNYITPVN 130

Query: 82  ----HGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHR-QVKHYRIFR 136
               H W    + R  AE LL       GSF++RESE+  G  S+S+R+  +V HYRI  
Sbjct: 131 SLEKHSWYHGPVSRSAAEYLLS--SLINGSFLVRESESSPGQLSISLRYEGRVYHYRINT 188

Query: 137 LPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTP 174
             +   Y++    F  L +LV+H+S VADGL   L  P
Sbjct: 189 TADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYP 226


>gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]
          Length = 620

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 59/193 (30%), Positives = 86/193 (44%), Gaps = 23/193 (11%)

Query: 8   TPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVI-SDEGGWWKAISLST 66
           TP    RPL  PE      +  L DY + D      RR E+  ++ S E  WW+ +    
Sbjct: 160 TPEDNRRPLWEPE---ETVVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWR-VQDRN 215

Query: 67  GRESYIPGICVAR------VYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY 120
           G E Y+P   +          + W  + + RDKAE+LL L   K G+FM+R+S T  G Y
Sbjct: 216 GHEGYVPSSYLVEKSPNNLETYEWYNKSISRDKAEKLL-LDTGKEGAFMVRDSRT-AGTY 273

Query: 121 SLSVRHRQV--------KHYRIFRLPNN--WYYISPRLTFQCLEDLVNHYSEVADGLCCV 170
           ++SV  + V        KHY I    +N   YY++ +  F  +  L+N++     GL   
Sbjct: 274 TVSVFTKAVVSENNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTR 333

Query: 171 LTTPCLTQSTAAP 183
           L  P       AP
Sbjct: 334 LRYPVCFGRQKAP 346


>gi|4557377 Bruton agammaglobulinemia tyrosine kinase [Homo sapiens]
          Length = 659

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 50/189 (26%), Positives = 91/189 (48%), Gaps = 19/189 (10%)

Query: 9   PAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEG-GWWKAISLSTG 67
           P PA  P+   E      +  L DY   + +    R+G++  ++ +    WW+A     G
Sbjct: 204 PEPAAAPVSTSE---LKKVVALYDYMPMNANDLQLRKGDEYFILEESNLPWWRARD-KNG 259

Query: 68  RESYIPGICVARV-----YHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSL 122
           +E YIP   V         + W  + + R +AE+LL+  + K G F++R+S +K G Y++
Sbjct: 260 QEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLK-QEGKEGGFIVRDS-SKAGKYTV 317

Query: 123 SVRHRQ-------VKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPC 175
           SV  +        ++HY +   P + YY++ +  F  + +L+N++   + GL   L  P 
Sbjct: 318 SVFAKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPV 377

Query: 176 LTQSTAAPA 184
             Q+  AP+
Sbjct: 378 SQQNKNAPS 386


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,540,458
Number of Sequences: 37866
Number of extensions: 543878
Number of successful extensions: 1848
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 1687
Number of HSP's gapped (non-prelim): 175
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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