Search of human proteins with 113930703

Search of human proteins with 113930703

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113930703 early B-cell factor 2 [Homo sapiens]
         (575 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113930703 early B-cell factor 2 [Homo sapiens]                    1162   0.0  
gi|53828926 early B-cell factor 3 [Homo sapiens]                      951   0.0  
gi|31415878 early B-cell factor [Homo sapiens]                        929   0.0  
gi|160333411 early B-cell factor 4 [Homo sapiens]                     828   0.0  
gi|40538736 RAN binding protein 10 [Homo sapiens]                      42   0.001
gi|153791670 keratin 76 [Homo sapiens]                                 41   0.003
gi|209863002 MAP-kinase activating death domain-containing prote...    40   0.006
gi|83367077 mucin 16 [Homo sapiens]                                    40   0.006
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]              40   0.006
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]               40   0.006
gi|209862998 MAP-kinase activating death domain-containing prote...    40   0.008
gi|209571517 MAP-kinase activating death domain-containing prote...    40   0.008
gi|209862994 MAP-kinase activating death domain-containing prote...    39   0.017
gi|18860873 MAP-kinase activating death domain-containing protei...    39   0.017
gi|209862987 MAP-kinase activating death domain-containing prote...    39   0.017
gi|209862983 MAP-kinase activating death domain-containing prote...    39   0.017
gi|209862979 MAP-kinase activating death domain-containing prote...    39   0.017
gi|209862975 MAP-kinase activating death domain-containing prote...    39   0.017
gi|209862971 MAP-kinase activating death domain-containing prote...    39   0.017
gi|28373194 adhesion regulating molecule 1 precursor [Homo sapiens]    39   0.017
gi|28373192 adhesion regulating molecule 1 precursor [Homo sapiens]    39   0.017
gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]              38   0.022
gi|239749213 PREDICTED: mucin 3B, cell surface associated, parti...    38   0.022
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             38   0.022
gi|67782356 corneodesmosin precursor [Homo sapiens]                    38   0.029
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor...    37   0.038
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor...    37   0.038
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor...    37   0.038
gi|13491168 pumilio homolog 2 [Homo sapiens]                           37   0.038
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         37   0.038

>gi|113930703 early B-cell factor 2 [Homo sapiens]
          Length = 575

 Score = 1162 bits (3005), Expect = 0.0
 Identities = 575/575 (100%), Positives = 575/575 (100%)

Query: 1   MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSN 60
           MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSN
Sbjct: 1   MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSN 60

Query: 61  LRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVR 120
           LRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVR
Sbjct: 61  LRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVR 120

Query: 121 TEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV 180
           TEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV
Sbjct: 121 TEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV 180

Query: 181 IIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHG 240
           IIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHG
Sbjct: 181 IIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHG 240

Query: 241 RRARRLDPSEATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHA 300
           RRARRLDPSEATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHA
Sbjct: 241 RRARRLDPSEATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHA 300

Query: 301 IRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVIPRHPGD 360
           IRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVIPRHPGD
Sbjct: 301 IRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVIPRHPGD 360

Query: 361 PERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQLPALSSSPA 420
           PERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQLPALSSSPA
Sbjct: 361 PERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQLPALSSSPA 420

Query: 421 HSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMN 480
           HSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMN
Sbjct: 421 HSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMN 480

Query: 481 GYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKS 540
           GYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKS
Sbjct: 481 GYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKS 540

Query: 541 AFAPVIRPQGSPSPACSSGNGNGFRAMTGLVVPPM 575
           AFAPVIRPQGSPSPACSSGNGNGFRAMTGLVVPPM
Sbjct: 541 AFAPVIRPQGSPSPACSSGNGNGFRAMTGLVVPPM 575


>gi|53828926 early B-cell factor 3 [Homo sapiens]
          Length = 551

 Score =  951 bits (2457), Expect = 0.0
 Identities = 468/577 (81%), Positives = 507/577 (87%), Gaps = 28/577 (4%)

Query: 1   MFGIQDTLGRG-PTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPS 59
           MFGIQ+ + RG  T+KE+ LG+ M+ VRSW+   GVVDAN AAQSGV L+RAHFEKQPPS
Sbjct: 1   MFGIQENIPRGGTTMKEEPLGSGMNPVRSWMHTAGVVDANTAAQSGVGLARAHFEKQPPS 60

Query: 60  NLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGV 119
           NLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVE +KE  NEKTNNG HYKLQLLYSNGV
Sbjct: 61  NLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVEKEKEPNNEKTNNGIHYKLQLLYSNGV 120

Query: 120 RTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDP 179
           RTEQDLYVRLIDS+TKQ I YEGQ+KNPEMCRVLLTHE+MCSRCC+KKSCGNRNETPSDP
Sbjct: 121 RTEQDLYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDP 180

Query: 180 VIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKH 239
           VIIDRFFLKFFLKCNQNCLK AGNPRDMRRFQVV+STTVNVDGHVLAVSDNMFVHNNSKH
Sbjct: 181 VIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKH 240

Query: 240 GRRARRLDPSEATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPH 299
           GRRARRLDPSEATPCIKAISPSEGWTTGGA VIIIGDNFFDGLQVVFGTMLVWSELITPH
Sbjct: 241 GRRARRLDPSEATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVVFGTMLVWSELITPH 300

Query: 300 AIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVIPRHPG 359
           AIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRF+YTALNEPTIDYGFQRLQKVIPRHPG
Sbjct: 301 AIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVYTALNEPTIDYGFQRLQKVIPRHPG 360

Query: 360 DPERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQLPALSSSP 419
           DPERL KE+LLKRAADLVEALYG PHNNQ+IILKRAADIAEALYSVPRN +Q+P L ++P
Sbjct: 361 DPERLPKEVLLKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQIPTLGNNP 420

Query: 420 AHSGMMGINSYGSQLGVSISESTQGNNQ-GYIRNTSSISPRGYSSSSTPQQSNYSTSSNS 478
           AH+GMMG+NS+ SQL V++SE++Q N+Q GY RNTSS+SPRGY  SSTPQQSNY+T S S
Sbjct: 421 AHTGMMGVNSFSSQLAVNVSETSQANDQVGYSRNTSSVSPRGYVPSSTPQQSNYNTVSTS 480

Query: 479 MNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQ 538
           MNGY +  MA+LGVPGSPGFLNGS   SPYG                          +KQ
Sbjct: 481 MNGYGSGAMASLGVPGSPGFLNGSSANSPYG--------------------------MKQ 514

Query: 539 KSAFAPVIRPQGSPSPACSSGNGNGFRAMTGLVVPPM 575
           KSAFAPV+RPQ SP P+C+S NGNG +AM+GLVVPPM
Sbjct: 515 KSAFAPVVRPQASPPPSCTSANGNGLQAMSGLVVPPM 551


>gi|31415878 early B-cell factor [Homo sapiens]
          Length = 591

 Score =  929 bits (2401), Expect = 0.0
 Identities = 456/593 (76%), Positives = 517/593 (87%), Gaps = 20/593 (3%)

Query: 1   MFGIQDTLGR-GPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPS 59
           MFGIQ+++ R G ++KE+ LG+ M++VR+W++  GV+DAN AAQSGV L+RAHFEKQPPS
Sbjct: 1   MFGIQESIQRSGSSMKEEPLGSGMNAVRTWMQGAGVLDANTAAQSGVGLARAHFEKQPPS 60

Query: 60  NLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGV 119
           NLRKSNFFHFVLALYDRQGQPVEIERTAFV FVE +KE  +EKTNNG HY+LQLLYSNG+
Sbjct: 61  NLRKSNFFHFVLALYDRQGQPVEIERTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGI 120

Query: 120 RTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDP 179
           RTEQD YVRLIDS+TKQ I YEGQ+KNPEMCRVLLTHE+MCSRCC+KKSCGNRNETPSDP
Sbjct: 121 RTEQDFYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDP 180

Query: 180 VIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKH 239
           VIIDRFFLKFFLKCNQNCLK AGNPRDMRRFQVV+STTVNVDGHVLAVSDNMFVHNNSKH
Sbjct: 181 VIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKH 240

Query: 240 GRRARRLDPSE--------ATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLV 291
           GRRARRLDPSE        ATPCIKAISPSEGWTTGGA VIIIGDNFFDGLQV+FGTMLV
Sbjct: 241 GRRARRLDPSEGTPSYLEHATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVIFGTMLV 300

Query: 292 WSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYTALNEPTIDYGFQRLQ 351
           WSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKG PGRFIYTALNEPTIDYGFQRLQ
Sbjct: 301 WSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRFIYTALNEPTIDYGFQRLQ 360

Query: 352 KVIPRHPGDPERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQ 411
           KVIPRHPGDPERL KE++LKRAADLVEALYG PHNNQ+IILKRAADIAEALYSVPRN +Q
Sbjct: 361 KVIPRHPGDPERLPKEVILKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQ 420

Query: 412 LPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSN 471
           LPAL+++  H+GMMG+NS+  QL V++SE++Q  NQG+ RN+SS+SP GY  S+TPQQ+N
Sbjct: 421 LPALANTSVHAGMMGVNSFSGQLAVNVSEASQATNQGFTRNSSSVSPHGYVPSTTPQQTN 480

Query: 472 YSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGS--------SSTS 523
           Y++ + SMNGY +  M+NLG  GSP FLNGS   SPY I+ SSPT+ S        SS+S
Sbjct: 481 YNSVTTSMNGYGSAAMSNLG--GSPTFLNGSAANSPYAIVPSSPTMASSTSLPSNCSSSS 538

Query: 524 SILPFS-SSVFPAVKQKSAFAPVIRPQGSPSPACSSGNGNGFRAMTGLVVPPM 575
            I  FS +++  AVKQKSAFAPV+RPQ SP P C+S NGN  +A++G++VPPM
Sbjct: 539 GIFSFSPANMVSAVKQKSAFAPVVRPQTSPPPTCTSTNGNSLQAISGMIVPPM 591


>gi|160333411 early B-cell factor 4 [Homo sapiens]
          Length = 598

 Score =  828 bits (2139), Expect = 0.0
 Identities = 411/572 (71%), Positives = 472/572 (82%), Gaps = 14/572 (2%)

Query: 6   DTLGR-GPTLKEKSL-GAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRK 63
           D L R G  LKE+ L  A + SVRSW++  G++DA+ AAQSGV L+RAHFEKQPPSNLRK
Sbjct: 2   DALPRSGLNLKEEPLLPAGLGSVRSWMQGAGILDASTAAQSGVGLARAHFEKQPPSNLRK 61

Query: 64  SNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQ 123
           SNFFHFVLA+YDRQGQPVE+ERTAF+DFVE D+E G EKTNNG HY+L+L+Y+NG+RTEQ
Sbjct: 62  SNFFHFVLAMYDRQGQPVEVERTAFIDFVEKDREPGAEKTNNGIHYRLRLVYNNGLRTEQ 121

Query: 124 DLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIID 183
           DLYVRLIDS++KQ I YEGQ+KNPEMCRVLLTHE+MCSRCC++KSCGNRNETPSDPVIID
Sbjct: 122 DLYVRLIDSMSKQAIIYEGQDKNPEMCRVLLTHEIMCSRCCDRKSCGNRNETPSDPVIID 181

Query: 184 RFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRA 243
           RFFLKFFLKCNQNCLK AGNPRDMRRFQVV+STTV+VDGHVLAVSDNMFVHNNSKHGRRA
Sbjct: 182 RFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVSVDGHVLAVSDNMFVHNNSKHGRRA 241

Query: 244 RRLDPSE-ATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIR 302
           RRLDPSE ATPCIKAISP EGWTTGGA VI+IGDNFFDGLQVVFG +LVWSELITPHAIR
Sbjct: 242 RRLDPSEAATPCIKAISPGEGWTTGGATVIVIGDNFFDGLQVVFGNVLVWSELITPHAIR 301

Query: 303 VQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPE 362
           VQTPPRHIPGVVEVTLSYKSKQFCKG PGRF+YTALNEPTIDYGFQRLQKVIPRHPGDPE
Sbjct: 302 VQTPPRHIPGVVEVTLSYKSKQFCKGCPGRFVYTALNEPTIDYGFQRLQKVIPRHPGDPE 361

Query: 363 RLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQLPALSSSPAHS 422
           RL KE+LLKRAADL EALYG P +NQ+++LKRAAD+AEALYS PR P  L  L+ S  H 
Sbjct: 362 RLPKEVLLKRAADLAEALYGVPGSNQELLLKRAADVAEALYSTPRAPGPLAPLAPSHPHP 421

Query: 423 GMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNS-MNG 481
            ++GIN++ S L +++ ++T G   GY R+ SS SPRG++ S   QQS Y     + + G
Sbjct: 422 AVVGINAFSSPLAIAVGDATPGPEPGYARSCSSASPRGFAPSPGSQQSGYGGGLGAGLGG 481

Query: 482 YSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSS---------TSSILPFSS-S 531
           Y    +A LGVPGSP FLNGS   SP+ IM SSP + ++S         T+S+  FS  +
Sbjct: 482 YGAPGVAGLGVPGSPSFLNGSTATSPFAIMPSSPPLAAASSMSLPAAAPTTSVFSFSPVN 541

Query: 532 VFPAVKQKSAFAPVIRPQGSPSPACSSGNGNG 563
           +  AVKQ+SAFAPV+RP  SP  AC   +G G
Sbjct: 542 MISAVKQRSAFAPVLRPPSSPPQACPRAHGEG 573


>gi|40538736 RAN binding protein 10 [Homo sapiens]
          Length = 620

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/160 (25%), Positives = 68/160 (42%), Gaps = 5/160 (3%)

Query: 357 HPGDPERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQLPALS 416
           +PG  E     + + +    VE + GT    + +    ++   ++  S P +PS  P   
Sbjct: 318 YPGLLEHNPNLLFMLKCRQFVEMVNGTDSEVRSL----SSRSPKSQDSYPGSPSLSPRHG 373

Query: 417 SSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSS 476
            S +H    G +S     GV+ ++S Q N+  Y   +SS S    SSSS+P   NYS S+
Sbjct: 374 PSSSHMHNTGADSPSCSNGVASTKSKQ-NHSKYPAPSSSSSSSSSSSSSSPSSVNYSESN 432

Query: 477 NSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPT 516
           ++ +  S    +      S   +       P G++ S  T
Sbjct: 433 STDSTKSQHHSSTSNQETSDSEMEMEAEHYPNGVLGSMST 472



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 3/79 (3%)

Query: 450 IRNTSSISPRG---YSSSSTPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGS 506
           +R+ SS SP+    Y  S +    +  +SS+  N  ++ P  + GV  +    N S   +
Sbjct: 348 VRSLSSRSPKSQDSYPGSPSLSPRHGPSSSHMHNTGADSPSCSNGVASTKSKQNHSKYPA 407

Query: 507 PYGIMSSSPTVGSSSTSSI 525
           P    SSS +  SSS SS+
Sbjct: 408 PSSSSSSSSSSSSSSPSSV 426


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 5/93 (5%)

Query: 436 VSISESTQGNNQGYIRNTSSISPRGYSS-SSTPQQSNYSTSSNSMNGYSNVPMANLGVPG 494
           V+ +  + G+++G     S     GY   SS+   S Y  S  S +GY  V   + G  G
Sbjct: 512 VTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRG 571

Query: 495 SPGFLNGSPTGSPYG----IMSSSPTVGSSSTS 523
           S G    S +GS  G    I  S   +GSSS S
Sbjct: 572 SSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGS 604


>gi|209863002 MAP-kinase activating death domain-containing protein
            isoform j [Homo sapiens]
          Length = 1541

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 8/112 (7%)

Query: 435  GVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV-P 493
            GVS++ S+Q  +Q  +     +SP     SS+ Q S  S SS    G  +   +N G  P
Sbjct: 1083 GVSLTSSSQRTDQDSV---IGVSPAVMIRSSS-QDSEVSNSSGETLGADSDLSSNAGDGP 1138

Query: 494  GSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1139 GGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1187


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 42/182 (23%), Positives = 75/182 (41%), Gaps = 7/182 (3%)

Query: 372  RAADLVEALYGTPHNNQ-DIILKRAADIAEALYSVPRNPSQLPALSSSPAHSGMMGINSY 430
            R  D V++   +  NN  + +LK +   AE   S+      L   S SP  S +   ++ 
Sbjct: 6187 RTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTS 6246

Query: 431  GSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANL 490
                  S+   T         N   ++    +  +T   S  +T +++M+   N  +AN+
Sbjct: 6247 SLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANV 6306

Query: 491  GVPGSPG--FLNGSPTGSPYGIMSS---SPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G   SP   +   SP   PY   S+   + T G S  S+ +P  SS    ++ ++ F+ +
Sbjct: 6307 GTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMP-RSSAMKKIESETTFSLI 6365

Query: 546  IR 547
             R
Sbjct: 6366 FR 6367



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 9/104 (8%)

Query: 437   SISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGVPGSP 496
             SI+EST   +    R T S++   +  S+    S  + S+ ++    +  M +    G P
Sbjct: 10236 SITESTGITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVP 10295

Query: 497   GFLNGSPTGSPYGIMSSSPTVGSSST-------SSILPFSSSVF 533
               ++GS  GSP+    S P   + ST       S+ +PFSSS F
Sbjct: 10296 RAISGS--GSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTF 10337



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 43/156 (27%), Positives = 58/156 (37%), Gaps = 7/156 (4%)

Query: 410   SQLPALSSSPAHSGMMGINSYGSQLGVSISES-TQGNNQGYIRNTSSISPRGYSSSSTPQ 468
             SQ   + S  AH G    +S    L VS  E  T  +   +   +SS  PR  S  S  +
Sbjct: 11230 SQPETIDSWVAHPGTEA-SSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSE 11288

Query: 469   QSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPF 528
                  ++  S    S+  ++    PG PG L    T S   I ++ PTV  S   S    
Sbjct: 11289 LDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATA 11348

Query: 529   SSSVFPAVKQKSAFAPV-----IRPQGSPSPACSSG 559
             S    PAV   +            P  +PS A S G
Sbjct: 11349 SWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPG 11384



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 37/173 (21%), Positives = 73/173 (42%), Gaps = 15/173 (8%)

Query: 401  ALYSVPRNPSQLPALSSSPAH--SGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISP 458
            +L S P   S  P  S+SP    S  + + +  + + V+ ++     +   + +    SP
Sbjct: 5337 SLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTS----SP 5392

Query: 459  RGYSSSSTPQQSNYSTSSNS---MNGYSNVPMANLGVPGS-----PGFLNGSPTGSPYGI 510
               SS +  + + Y  ++++   M+  +N  + N+G  GS        L  S T     +
Sbjct: 5393 PNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPL 5452

Query: 511  MSSSPTVGSSSTSSILPFSSSVFPAVKQKSA-FAPVIRPQGSPSPACSSGNGN 562
            MS++ T+G +S S+  P  S       + +A  +P +R   +     S+   N
Sbjct: 5453 MSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETN 5505


>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 10/125 (8%)

Query: 439 SESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYS-NVPMANLGVPGSPG 497
           S S     + Y   +S++S R  +  ST  QS++ ++S  +   S  +P A+ G+P +  
Sbjct: 306 SPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANES 365

Query: 498 FLNGSPTGS--------PYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPVIRPQ 549
           FLNG+  G+         Y   S   +     T++ +P   S   A K K+ F   I P+
Sbjct: 366 FLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEA-KSKTEFDFNIDPK 424

Query: 550 GSPSP 554
            S  P
Sbjct: 425 PSEGP 429


>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
          Length = 1030

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 10/125 (8%)

Query: 439 SESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYS-NVPMANLGVPGSPG 497
           S S     + Y   +S++S R  +  ST  QS++ ++S  +   S  +P A+ G+P +  
Sbjct: 306 SPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANES 365

Query: 498 FLNGSPTGS--------PYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPVIRPQ 549
           FLNG+  G+         Y   S   +     T++ +P   S   A K K+ F   I P+
Sbjct: 366 FLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEA-KSKTEFDFNIDPK 424

Query: 550 GSPSP 554
            S  P
Sbjct: 425 PSEGP 429


>gi|209862998 MAP-kinase activating death domain-containing protein
            isoform i [Homo sapiens]
          Length = 1544

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 435  GVSISESTQGNNQGYIRNTS-SISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV- 492
            GVS++ S+Q  +Q  +   S ++  R  SSS   + S  S SS    G  +   +N G  
Sbjct: 1083 GVSLTSSSQRTDQDSVIGVSPAVMIR--SSSQDSEVSTVSNSSGETLGADSDLSSNAGDG 1140

Query: 493  PGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            PG  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1141 PGGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1190


>gi|209571517 MAP-kinase activating death domain-containing protein
            isoform h [Homo sapiens]
          Length = 1587

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 435  GVSISESTQGNNQGYIRNTS-SISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV- 492
            GVS++ S+Q  +Q  +   S ++  R  SSS   + S  S SS    G  +   +N G  
Sbjct: 1126 GVSLTSSSQRTDQDSVIGVSPAVMIR--SSSQDSEVSTVSNSSGETLGADSDLSSNAGDG 1183

Query: 493  PGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            PG  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1184 PGGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1233


>gi|209862994 MAP-kinase activating death domain-containing protein
            isoform d [Homo sapiens]
          Length = 1647

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 4/112 (3%)

Query: 435  GVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV-P 493
            GVS++ S+Q  +Q  +   S       SS  +   +  S SS    G  +   +N G  P
Sbjct: 1164 GVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGP 1223

Query: 494  GSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1224 GGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1272


>gi|18860873 MAP-kinase activating death domain-containing protein
            isoform g [Homo sapiens]
          Length = 1581

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 4/112 (3%)

Query: 435  GVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV-P 493
            GVS++ S+Q  +Q  +   S       SS  +   +  S SS    G  +   +N G  P
Sbjct: 1164 GVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGP 1223

Query: 494  GSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1224 GGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1272


>gi|209862987 MAP-kinase activating death domain-containing protein
            isoform f [Homo sapiens]
          Length = 1479

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 4/112 (3%)

Query: 435  GVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV-P 493
            GVS++ S+Q  +Q  +   S       SS  +   +  S SS    G  +   +N G  P
Sbjct: 1083 GVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGP 1142

Query: 494  GSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1143 GGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1191


>gi|209862983 MAP-kinase activating death domain-containing protein
            isoform e [Homo sapiens]
          Length = 1608

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 4/112 (3%)

Query: 435  GVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV-P 493
            GVS++ S+Q  +Q  +   S       SS  +   +  S SS    G  +   +N G  P
Sbjct: 1146 GVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGP 1205

Query: 494  GSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1206 GGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1254


>gi|209862979 MAP-kinase activating death domain-containing protein
            isoform c [Homo sapiens]
          Length = 1545

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 4/112 (3%)

Query: 435  GVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV-P 493
            GVS++ S+Q  +Q  +   S       SS  +   +  S SS    G  +   +N G  P
Sbjct: 1083 GVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGP 1142

Query: 494  GSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1143 GGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1191


>gi|209862975 MAP-kinase activating death domain-containing protein
            isoform b [Homo sapiens]
          Length = 1565

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 4/112 (3%)

Query: 435  GVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV-P 493
            GVS++ S+Q  +Q  +   S       SS  +   +  S SS    G  +   +N G  P
Sbjct: 1103 GVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGP 1162

Query: 494  GSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1163 GGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1211


>gi|209862971 MAP-kinase activating death domain-containing protein
            isoform a [Homo sapiens]
          Length = 1588

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 4/112 (3%)

Query: 435  GVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGV-P 493
            GVS++ S+Q  +Q  +   S       SS  +   +  S SS    G  +   +N G  P
Sbjct: 1126 GVSLTSSSQRTDQDSVIGVSPAVMIRSSSQDSEVSTVVSNSSGETLGADSDLSSNAGDGP 1185

Query: 494  GSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPV 545
            G  G ++     S  G +S S    +S+TS+I   + S+ P++K+K A +P+
Sbjct: 1186 GGEGSVH---LASSRGTLSDSEIETNSATSTIFGKAHSLKPSIKEKLAGSPI 1234


>gi|28373194 adhesion regulating molecule 1 precursor [Homo sapiens]
          Length = 407

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/80 (40%), Positives = 38/80 (47%), Gaps = 9/80 (11%)

Query: 488 ANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSA------ 541
           A LG  G  G L G    S   ++ SS   GSSS+SS    S++V P+    S       
Sbjct: 175 AGLGGLGGLGALTGPGLAS---LLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAP 231

Query: 542 FAPVIRPQGSPSPACSSGNG 561
            AP      SPSPA SSGNG
Sbjct: 232 SAPAAASATSPSPAPSSGNG 251


>gi|28373192 adhesion regulating molecule 1 precursor [Homo sapiens]
          Length = 407

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 32/80 (40%), Positives = 38/80 (47%), Gaps = 9/80 (11%)

Query: 488 ANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSA------ 541
           A LG  G  G L G    S   ++ SS   GSSS+SS    S++V P+    S       
Sbjct: 175 AGLGGLGGLGALTGPGLAS---LLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAP 231

Query: 542 FAPVIRPQGSPSPACSSGNG 561
            AP      SPSPA SSGNG
Sbjct: 232 SAPAAASATSPSPAPSSGNG 251


>gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]
          Length = 1586

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 16/119 (13%)

Query: 398  IAEALYSVPRNPSQLPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQ---GYIRNTS 454
            I+ AL   P++ S +PA    P H G      +  Q  V+   +T GN     G   +  
Sbjct: 1259 ISGALNQFPQSCSNMPA---KPGHLG------HPQQTEVAPDPTTMGNRHRELGVPDSAL 1309

Query: 455  SISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSS 513
            +  P  +   S PQQS++  +S S  GY  VP  +L     PGF+   P   P G+ ++
Sbjct: 1310 AGVPPPHPVQSYPQQSHHLAASMSQEGYHQVP--SLLPARQPGFM--EPQTGPMGVATA 1364


>gi|239749213 PREDICTED: mucin 3B, cell surface associated, partial
           [Homo sapiens]
          Length = 1063

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 40/151 (26%), Positives = 72/151 (47%), Gaps = 13/151 (8%)

Query: 410 SQLPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISP--RGYSS---S 464
           SQ P  S+   HS  +        L  S++ +++   + + R ++S +     +S+   S
Sbjct: 367 SQFPIPST---HSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWS 423

Query: 465 STPQQSNYSTSSNSMNGYSNVPMANL-GVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTS 523
           STP  +   +SS S    + V    +  VP SP   +    GS    +++ P++ SSST+
Sbjct: 424 STP--TIIMSSSPSSASITPVFATTIHSVPSSPYIFSTENVGS--ASITAFPSLSSSSTT 479

Query: 524 SILPFSSSVFPAVKQKSAFAPVIRPQGSPSP 554
           S  P SSS+  A+ + + F+ +  P  +P P
Sbjct: 480 STSPTSSSLTTALTEITPFSYISLPSTTPCP 510



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 21/118 (17%)

Query: 439 SESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYS-NVPMANL------- 490
           S ST       I +T S S    +S  T  ++  +++ +S +  S ++P  +L       
Sbjct: 176 SHSTPSFTSSTIHSTVSSSTTAITSPFTTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLS 235

Query: 491 -----------GVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVK 537
                       +P  P  ++  PT  P  I+SSSP++ S+ TSS++  +S     V+
Sbjct: 236 LSTSTSLTTTTDLPSIPTDISSLPT--PIHIISSSPSIQSTETSSLVGTTSPTMSTVR 291


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 51/162 (31%), Positives = 64/162 (39%), Gaps = 23/162 (14%)

Query: 408  NPSQLPALSSSPAHSGMMG-----INSYGSQLGVSISESTQGNNQ----GYIRNTSSISP 458
            +P   PA S +P   G  G     I S G  +  S S ++         GY   + S SP
Sbjct: 1558 SPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSP 1617

Query: 459  RGYSSSST-----PQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSS 513
               S S T     P   NYS +S S +     P +    P SP +   SP+ SP    S 
Sbjct: 1618 TSPSYSPTSPSYSPTSPNYSPTSPSYS-----PTSPSYSPTSPSYSPTSPSYSPTS-PSY 1671

Query: 514  SPTVGSSS--TSSILPFSSSVFPAVKQKSAFAPVIRPQGSPS 553
            SPT  S S  + S  P S S  P     S  +P   P  SPS
Sbjct: 1672 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT-SPS 1712



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 44/155 (28%), Positives = 65/155 (41%), Gaps = 10/155 (6%)

Query: 406  PRNPSQLPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSS 465
            P++PS  P   +SP++S      S  S      S S    +  Y   + S SP   S S 
Sbjct: 1610 PQSPSYSP---TSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1666

Query: 466  TPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSI 525
            T    + ++ S S    S  P +    P SP +   SP+ SP     +SP+  S ++ S 
Sbjct: 1667 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-----TSPSY-SPTSPSY 1720

Query: 526  LPFSSSVFPAVKQKSAFAPVIRPQGSPSPACSSGN 560
             P S S  P     S  +P   P  SP+ + +S N
Sbjct: 1721 SPTSPSYSPTSPSYSPTSPSYSPT-SPNYSPTSPN 1754



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 47/151 (31%), Positives = 60/151 (39%), Gaps = 17/151 (11%)

Query: 409  PSQLPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQ 468
            P+ +P L ++   +GM    S  S +G  IS +    NQG      + SP    S  TP 
Sbjct: 1487 PTNIPGLGAA-GPTGMF-FGSAPSPMG-GISPAMTPWNQGATPAYGAWSP-SVGSGMTPG 1542

Query: 469  QSNYSTSSNS-----MNGYSNVPMANLGVPGSPGFLNGSP-TGSPYGIMS-----SSPTV 517
             + +S S+ S       GYS       G PGSPG    SP   SP G MS     +SP  
Sbjct: 1543 AAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPG--PSSPYIPSPGGAMSPSYSPTSPAY 1600

Query: 518  GSSSTSSILPFSSSVFPAVKQKSAFAPVIRP 548
               S     P S S  P     S  +P   P
Sbjct: 1601 EPRSPGGYTPQSPSYSPTSPSYSPTSPSYSP 1631



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 43/153 (28%), Positives = 63/153 (41%), Gaps = 10/153 (6%)

Query: 406  PRNPSQLPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSS 465
            P +PS  P   +SP++S      S  S      S S    +  Y   + S SP   S S 
Sbjct: 1666 PTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1722

Query: 466  TPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSI 525
            T    + ++ S S    S  P +    P SP +   SP+ SP     +SP+  S ++ + 
Sbjct: 1723 TSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSP-----TSPSY-SPTSPNY 1776

Query: 526  LPFSSSVFPAVKQKSAFAPVIRPQGSPSPACSS 558
             P S +  P     S  +P   P  SPS + SS
Sbjct: 1777 TPTSPNYSPTSPSYSPTSPSYSPT-SPSYSPSS 1808



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 20/94 (21%)

Query: 483  SNVPMANLGVPGSPGFLNGSPTGSPYGIMSS---------------SPTVGSSSTSSILP 527
            +N+P   LG  G  G   GS      GI  +               SP+VGS  T     
Sbjct: 1488 TNIP--GLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAG 1545

Query: 528  FSSSVFPAVKQKSAFAPVIRPQGSPSPACSSGNG 561
            FS S   A    S F+P   P  SP+P      G
Sbjct: 1546 FSPS---AASDASGFSPGYSPAWSPTPGSPGSPG 1576



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 6/145 (4%)

Query: 406  PRNPSQLPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSS 465
            P +PS  P   +SP +S      +  S      S S    +  Y   + + SP   S S 
Sbjct: 1736 PTSPSYSP---TSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSP 1792

Query: 466  TPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSS- 524
            T    + ++ S S +     P +    P SP +   SP+ SP      +PT  S S SS 
Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTS-PKYTPTSPSYSPSSP 1851

Query: 525  -ILPFSSSVFPAVKQKSAFAPVIRP 548
               P S    P   + S  +P   P
Sbjct: 1852 EYTPTSPKYSPTSPKYSPTSPKYSP 1876


>gi|67782356 corneodesmosin precursor [Homo sapiens]
          Length = 529

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 52/180 (28%), Positives = 72/180 (40%), Gaps = 32/180 (17%)

Query: 417 SSPAHSGMMGINSYGSQLGVSISES-TQGNNQGYIRNTSSISPRGYSSSSTPQQSNYS-- 473
           SS + S + G +   SQLG S S S + G++ G   + SS S     SSS+ Q  N S  
Sbjct: 118 SSGSGSSLQGASG-SSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSAL 176

Query: 474 -TSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSS--TSSILPFS- 529
            T+ NS  G  N        P  PG    S +   +G+ SS  +V S+    SS +P S 
Sbjct: 177 PTNDNSYRGILN--------PSQPG--QSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSP 226

Query: 530 SSVFPAVKQKSAFAP--------------VIRPQGSPSPACSSGNGNGFRAMTGLVVPPM 575
            S  P V     + P              V+   GS +P    G       + G   PP+
Sbjct: 227 CSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPI 286



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 39/117 (33%), Positives = 51/117 (43%), Gaps = 24/117 (20%)

Query: 417 SSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSS 476
           SS + +   G  S GS  G SI+   QG + G  +  +  S   YSS           S 
Sbjct: 76  SSISSARSSGGGSSGSSSGSSIA---QGGSAGSFKPGTGYSQVSYSSG----------SG 122

Query: 477 NSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVF 533
           +S+ G S    + LG   S    +GS +GS     SSS     SS+SS   FSSS F
Sbjct: 123 SSLQGASG--SSQLGSSSSHSGSSGSHSGS-----SSS----HSSSSSSFQFSSSSF 168


>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
           [Homo sapiens]
          Length = 709

 Score = 37.4 bits (85), Expect = 0.038
 Identities = 31/115 (26%), Positives = 47/115 (40%), Gaps = 8/115 (6%)

Query: 465 STPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSS 524
           +TP  S  S  S S N   N P+      G     NG  + +P  +  +SP+  + S+S 
Sbjct: 465 TTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSTAPQRVPVASPSAHNISSSG 524

Query: 525 ILPFSSSVFPAVKQKSAF-----APVIRPQGSP---SPACSSGNGNGFRAMTGLV 571
             P  ++    V  +S F       V   Q  P   +PA  SG+  G R  +G +
Sbjct: 525 GAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSI 579


>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
           [Homo sapiens]
          Length = 719

 Score = 37.4 bits (85), Expect = 0.038
 Identities = 31/115 (26%), Positives = 47/115 (40%), Gaps = 8/115 (6%)

Query: 465 STPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSS 524
           +TP  S  S  S S N   N P+      G     NG  + +P  +  +SP+  + S+S 
Sbjct: 466 TTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSTAPQRVPVASPSAHNISSSG 525

Query: 525 ILPFSSSVFPAVKQKSAF-----APVIRPQGSP---SPACSSGNGNGFRAMTGLV 571
             P  ++    V  +S F       V   Q  P   +PA  SG+  G R  +G +
Sbjct: 526 GAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSI 580


>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
           [Homo sapiens]
          Length = 724

 Score = 37.4 bits (85), Expect = 0.038
 Identities = 31/115 (26%), Positives = 47/115 (40%), Gaps = 8/115 (6%)

Query: 465 STPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSS 524
           +TP  S  S  S S N   N P+      G     NG  + +P  +  +SP+  + S+S 
Sbjct: 465 TTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSTAPQRVPVASPSAHNISSSG 524

Query: 525 ILPFSSSVFPAVKQKSAF-----APVIRPQGSP---SPACSSGNGNGFRAMTGLV 571
             P  ++    V  +S F       V   Q  P   +PA  SG+  G R  +G +
Sbjct: 525 GAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSI 579


>gi|13491168 pumilio homolog 2 [Homo sapiens]
          Length = 1064

 Score = 37.4 bits (85), Expect = 0.038
 Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 19/126 (15%)

Query: 427 INSYGSQLGVSIS------ESTQGNNQGYIRNTSSISPRG---YSS---SSTPQQSNYST 474
           ++ +GS +G S S      ES   ++  Y R++SS++P G   Y+S   SS+P       
Sbjct: 567 LSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPL 626

Query: 475 SSNSMNGYSNVPMANLGVPGSPGFLN-GSPTGSPYGIMSSSPTV-----GSSSTSSILPF 528
            S +  G+S  P  +L   GS   L+ G  T      +S++P        +SSTSS+   
Sbjct: 627 PSQTP-GHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSS 685

Query: 529 SSSVFP 534
           SS +FP
Sbjct: 686 SSQLFP 691


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 37.4 bits (85), Expect = 0.038
 Identities = 40/139 (28%), Positives = 61/139 (43%), Gaps = 10/139 (7%)

Query: 416  SSSPAHSGMMGINSYGSQLGVSISESTQGNNQGYI------RNTSSISPRGYSSSSTPQQ 469
            SSS + SG    +S  S  G       +G+  G        RN S+ S R  S +S+   
Sbjct: 2559 SSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSS 2618

Query: 470  SNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFS 529
            S+ S+SS+S +  S+   ++     S    + S + S     SSS +  SSS+SS     
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSSSTTDED 2676

Query: 530  SSVFPAVKQKSAFAPVIRP 548
            SS   +   ++A AP   P
Sbjct: 2677 SSC--SSDDEAAPAPTAGP 2693



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 1/116 (0%)

Query: 453  TSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMS 512
            +SS S  G SSSS+   S+ S +     G  N      G  G       S   SP    S
Sbjct: 2559 SSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGD-GGCGTGGRNCSAASSRAASPASSSS 2617

Query: 513  SSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPVIRPQGSPSPACSSGNGNGFRAMT 568
            SS +  SSS+SS    SSS   +    S+ +       S S + SS + +   + T
Sbjct: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTT 2673



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 7/112 (6%)

Query: 382  GTPHNNQDIILKRAADIAEALYSVPRNPSQLPALSSSPAHSGMMGINSYGSQLGVSISES 441
            GT   N      RAA  A        + S   + SSS + S     +S  S    S S S
Sbjct: 2596 GTGGRNCSAASSRAASPAS-------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648

Query: 442  TQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGVP 493
            +  ++     ++SS S    SSS+T + S+ S+   +    +  P A   +P
Sbjct: 2649 SSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP 2700


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,910,322
Number of Sequences: 37866
Number of extensions: 1156501
Number of successful extensions: 4759
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 166
Number of HSP's that attempted gapping in prelim test: 4353
Number of HSP's gapped (non-prelim): 476
length of query: 575
length of database: 18,247,518
effective HSP length: 108
effective length of query: 467
effective length of database: 14,157,990
effective search space: 6611781330
effective search space used: 6611781330
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.