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Search of human proteins with 11386183
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11386183 WAS protein family, member 2 [Homo sapiens]
(498 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11386183 WAS protein family, member 2 [Homo sapiens] 1045 0.0
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 464 e-131
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 464 e-131
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 464 e-131
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 464 e-131
gi|13699803 WAS protein family, member 3 [Homo sapiens] 446 e-125
gi|160707881 formin 2 [Homo sapiens] 137 3e-32
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 134 2e-31
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 124 3e-28
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 118 1e-26
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 118 1e-26
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 110 3e-24
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 110 3e-24
gi|150417989 cyclin K isoform 1 [Homo sapiens] 108 1e-23
gi|157168329 formin 1 [Homo sapiens] 105 1e-22
gi|33356148 formin-like 1 [Homo sapiens] 103 3e-22
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 102 6e-22
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 102 1e-21
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 101 1e-21
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 101 1e-21
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 100 4e-21
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 100 5e-21
gi|153792074 proline rich 12 [Homo sapiens] 99 7e-21
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 98 2e-20
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 98 2e-20
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 97 3e-20
gi|210032580 SET domain containing 1B [Homo sapiens] 97 4e-20
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 96 6e-20
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 96 6e-20
gi|47132519 Ras association and pleckstrin homology domains 1 is... 96 8e-20
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 1045 bits (2702), Expect = 0.0
Identities = 498/498 (100%), Positives = 498/498 (100%)
Query: 1 MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANT 60
MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANT
Sbjct: 1 MPLVTRNIEPRHLCRQTLPSVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANT 60
Query: 61 FASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPV 120
FASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPV
Sbjct: 61 FASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPV 120
Query: 121 LETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRK 180
LETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRK
Sbjct: 121 LETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRK 180
Query: 181 EKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVEN 240
EKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVEN
Sbjct: 181 EKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVEN 240
Query: 241 VDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP 300
VDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP
Sbjct: 241 VDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP 300
Query: 301 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD 360
PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD
Sbjct: 301 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD 360
Query: 361 FAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL 420
FAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL
Sbjct: 361 FAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL 420
Query: 421 SDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQEKRDVVGNDVATILSRRIAVE 480
SDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQEKRDVVGNDVATILSRRIAVE
Sbjct: 421 SDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQEKRDVVGNDVATILSRRIAVE 480
Query: 481 YSDSEDDSSEFDEDDWSD 498
YSDSEDDSSEFDEDDWSD
Sbjct: 481 YSDSEDDSSEFDEDDWSD 498
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 464 bits (1194), Expect = e-131
Identities = 284/569 (49%), Positives = 335/569 (58%), Gaps = 85/569 (14%)
Query: 1 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 59
MPLV RNI+PRHLC LP +++ELECVTNI+LAN+IRQL SLSKYAEDIFGELF +A+
Sbjct: 1 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
Query: 60 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 119
+F+ RV+SL ERVDRL V VTQLDPKEEE+SLQ I RKAFRSSTIQDQ+LFDR +LP+P
Sbjct: 61 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
Query: 120 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 179
+ ETY+ C+ PPPLN LTPYRDDGKE LKFYT+PSYFFDLWKEKMLQDT+D KEKRK +
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
Query: 180 KEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKL---------GTSGY----PP 226
++ D P+ PR R+ EW+K+ G E E L G + + P
Sbjct: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
Query: 227 TLV-YQNGSIG---------------CVENVDASSYPPPPQSDSASSPSPSFSEDNLPPP 270
T V + +GS E V + PPP P P + P
Sbjct: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPP-------PPPMHGAGDAKPI 293
Query: 271 PAEFSYP---VDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPP 327
P S ++N+ S G + VSP+ PPP PPL S A + PPPP
Sbjct: 294 PTCISSATGLIENRPQSPATG-RTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPV 352
Query: 328 PMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP-------PPPPPAADYP---T 377
P PPPPP +P PPPP+P P APPP P PP A P T
Sbjct: 353 PP---PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCET 409
Query: 378 LPPPPLSQ-PTGGAPPPPPPP--PPPG--------------PP----PPPFTGADGQ-PA 415
+P PL Q G PPPPPPP PPPG PP P P T P
Sbjct: 410 VPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPL 469
Query: 416 IPP-------PLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRDVVGN 467
+PP P S+ + S+LP +SDARS LL AIR+G QLR+VEEQREQE K + + N
Sbjct: 470 MPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIEN 529
Query: 468 DVATILSRRIAVEYSDSEDDSSEFDEDDW 496
DVATILSRRIAVEYSDSEDD SEFDE DW
Sbjct: 530 DVATILSRRIAVEYSDSEDD-SEFDEVDW 557
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 464 bits (1194), Expect = e-131
Identities = 284/569 (49%), Positives = 335/569 (58%), Gaps = 85/569 (14%)
Query: 1 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 59
MPLV RNI+PRHLC LP +++ELECVTNI+LAN+IRQL SLSKYAEDIFGELF +A+
Sbjct: 1 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
Query: 60 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 119
+F+ RV+SL ERVDRL V VTQLDPKEEE+SLQ I RKAFRSSTIQDQ+LFDR +LP+P
Sbjct: 61 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
Query: 120 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 179
+ ETY+ C+ PPPLN LTPYRDDGKE LKFYT+PSYFFDLWKEKMLQDT+D KEKRK +
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
Query: 180 KEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKL---------GTSGY----PP 226
++ D P+ PR R+ EW+K+ G E E L G + + P
Sbjct: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
Query: 227 TLV-YQNGSIG---------------CVENVDASSYPPPPQSDSASSPSPSFSEDNLPPP 270
T V + +GS E V + PPP P P + P
Sbjct: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPP-------PPPMHGAGDAKPI 293
Query: 271 PAEFSYP---VDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPP 327
P S ++N+ S G + VSP+ PPP PPL S A + PPPP
Sbjct: 294 PTCISSATGLIENRPQSPATG-RTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPV 352
Query: 328 PMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP-------PPPPPAADYP---T 377
P PPPPP +P PPPP+P P APPP P PP A P T
Sbjct: 353 PP---PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCET 409
Query: 378 LPPPPLSQ-PTGGAPPPPPPP--PPPG--------------PP----PPPFTGADGQ-PA 415
+P PL Q G PPPPPPP PPPG PP P P T P
Sbjct: 410 VPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPL 469
Query: 416 IPP-------PLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRDVVGN 467
+PP P S+ + S+LP +SDARS LL AIR+G QLR+VEEQREQE K + + N
Sbjct: 470 MPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIEN 529
Query: 468 DVATILSRRIAVEYSDSEDDSSEFDEDDW 496
DVATILSRRIAVEYSDSEDD SEFDE DW
Sbjct: 530 DVATILSRRIAVEYSDSEDD-SEFDEVDW 557
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 464 bits (1194), Expect = e-131
Identities = 284/569 (49%), Positives = 335/569 (58%), Gaps = 85/569 (14%)
Query: 1 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 59
MPLV RNI+PRHLC LP +++ELECVTNI+LAN+IRQL SLSKYAEDIFGELF +A+
Sbjct: 1 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
Query: 60 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 119
+F+ RV+SL ERVDRL V VTQLDPKEEE+SLQ I RKAFRSSTIQDQ+LFDR +LP+P
Sbjct: 61 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
Query: 120 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 179
+ ETY+ C+ PPPLN LTPYRDDGKE LKFYT+PSYFFDLWKEKMLQDT+D KEKRK +
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
Query: 180 KEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKL---------GTSGY----PP 226
++ D P+ PR R+ EW+K+ G E E L G + + P
Sbjct: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
Query: 227 TLV-YQNGSIG---------------CVENVDASSYPPPPQSDSASSPSPSFSEDNLPPP 270
T V + +GS E V + PPP P P + P
Sbjct: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPP-------PPPMHGAGDAKPI 293
Query: 271 PAEFSYP---VDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPP 327
P S ++N+ S G + VSP+ PPP PPL S A + PPPP
Sbjct: 294 PTCISSATGLIENRPQSPATG-RTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPV 352
Query: 328 PMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP-------PPPPPAADYP---T 377
P PPPPP +P PPPP+P P APPP P PP A P T
Sbjct: 353 PP---PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCET 409
Query: 378 LPPPPLSQ-PTGGAPPPPPPP--PPPG--------------PP----PPPFTGADGQ-PA 415
+P PL Q G PPPPPPP PPPG PP P P T P
Sbjct: 410 VPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPL 469
Query: 416 IPP-------PLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRDVVGN 467
+PP P S+ + S+LP +SDARS LL AIR+G QLR+VEEQREQE K + + N
Sbjct: 470 MPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIEN 529
Query: 468 DVATILSRRIAVEYSDSEDDSSEFDEDDW 496
DVATILSRRIAVEYSDSEDD SEFDE DW
Sbjct: 530 DVATILSRRIAVEYSDSEDD-SEFDEVDW 557
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 464 bits (1194), Expect = e-131
Identities = 284/569 (49%), Positives = 335/569 (58%), Gaps = 85/569 (14%)
Query: 1 MPLVTRNIEPRHLCRQTLP-SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 59
MPLV RNI+PRHLC LP +++ELECVTNI+LAN+IRQL SLSKYAEDIFGELF +A+
Sbjct: 1 MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAH 60
Query: 60 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 119
+F+ RV+SL ERVDRL V VTQLDPKEEE+SLQ I RKAFRSSTIQDQ+LFDR +LP+P
Sbjct: 61 SFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIP 120
Query: 120 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 179
+ ETY+ C+ PPPLN LTPYRDDGKE LKFYT+PSYFFDLWKEKMLQDT+D KEKRK +
Sbjct: 121 LQETYDVCEQPPPLNILTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQK 180
Query: 180 KEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKL---------GTSGY----PP 226
++ D P+ PR R+ EW+K+ G E E L G + + P
Sbjct: 181 QKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDANLLHKHIEVANGPASHFETRPQ 240
Query: 227 TLV-YQNGSIG---------------CVENVDASSYPPPPQSDSASSPSPSFSEDNLPPP 270
T V + +GS E V + PPP P P + P
Sbjct: 241 TYVDHMDGSYSLSALPFSQMSELLTRAEERVLVRPHEPPP-------PPPMHGAGDAKPI 293
Query: 271 PAEFSYP---VDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPP 327
P S ++N+ S G + VSP+ PPP PPL S A + PPPP
Sbjct: 294 PTCISSATGLIENRPQSPATG-RTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPV 352
Query: 328 PMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP-------PPPPPAADYP---T 377
P PPPPP +P PPPP+P P APPP P PP A P T
Sbjct: 353 PP---PPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCET 409
Query: 378 LPPPPLSQ-PTGGAPPPPPPP--PPPG--------------PP----PPPFTGADGQ-PA 415
+P PL Q G PPPPPPP PPPG PP P P T P
Sbjct: 410 VPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPL 469
Query: 416 IPP-------PLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRDVVGN 467
+PP P S+ + S+LP +SDARS LL AIR+G QLR+VEEQREQE K + + N
Sbjct: 470 MPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIEN 529
Query: 468 DVATILSRRIAVEYSDSEDDSSEFDEDDW 496
DVATILSRRIAVEYSDSEDD SEFDE DW
Sbjct: 530 DVATILSRRIAVEYSDSEDD-SEFDEVDW 557
>gi|13699803 WAS protein family, member 3 [Homo sapiens]
Length = 502
Score = 446 bits (1148), Expect = e-125
Identities = 260/515 (50%), Positives = 321/515 (62%), Gaps = 30/515 (5%)
Query: 1 MPLVTRNIEPRHLCRQTLPS-VRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQAN 59
MPLV RNIEPRHLCR LP + SELECVTN TLA +IRQL SLSK+AEDIFGELF +AN
Sbjct: 1 MPLVKRNIEPRHLCRGALPEGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEAN 60
Query: 60 TFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVP 119
F R +SL +R+DRL VKVTQLD EEVSLQ IN +KAF+SST+QDQ++ +NS+P P
Sbjct: 61 NFYIRANSLQDRIDRLAVKVTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNP 120
Query: 120 VLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHR 179
V + YN D PPPLN LTPYRDD K+ LKFYTDPSYFFDLWKEKMLQDT+D KEKR+ +
Sbjct: 121 VADIYNQSDKPPPLNILTPYRDDKKDGLKFYTDPSYFFDLWKEKMLQDTEDKRKEKRRQK 180
Query: 180 KEKK-DNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCV 238
++K+ D R RK + R++EW M +E + +L S Y GS+
Sbjct: 181 EQKRIDGTTREVKKVRKARNRRQEWNMMAYDKE-LRPDNRLSQSVYHG--ASSEGSLSPD 237
Query: 239 ENVDAS-----SYPPPPQSDSASSP-SPSFSEDNLPP-PPAEFSYPVDNQRGSGLAGPKR 291
AS SYP P P +PS++ ++PP PA S +++ A +
Sbjct: 238 TRSHASDVTDYSYPATPNHSLHPQPVTPSYAAGDVPPHGPA--SQAAEHEYRPPSASARH 295
Query: 292 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
++ P PPP PP +P G + A P P G+ P + G PPPP
Sbjct: 296 MALNRPQQPPPPPPPQAPEGSQ-------ASAPMAPADYGMLPAQIIEYYNPSGPPPPPP 348
Query: 352 PPSFP-PHPDFAAP---PPPPPPPAADYPTLPPPPLSQPTG---GAPPPPPPPPPPGPPP 404
PP P F +P P PP PA+ T PP TG APPPP PPPPP PP
Sbjct: 349 PPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPPPGPPPPPPGPP 408
Query: 405 PPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQE-KRD 463
P + P PP+++ + + + P +SDARSDLL+AIR G QL++V+EQREQE KR+
Sbjct: 409 GPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAKRE 468
Query: 464 VVGNDVATILSRRIAVEYSDSEDDSSEFDEDDWSD 498
VGNDVATILSRRIAVEYSDS+DD SEFDE+DWSD
Sbjct: 469 PVGNDVATILSRRIAVEYSDSDDD-SEFDENDWSD 502
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 137 bits (344), Expect = 3e-32
Identities = 91/217 (41%), Positives = 99/217 (45%), Gaps = 46/217 (21%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP + P P +PPPP P+ G+G+ P PPP P
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPP-----PLP---GAGIPPPPPLPGAGIPPPPPLPGA 1072
Query: 307 G-SPPGPKPGFAPPPAPP------PPPPPM--IGIPPPPPPVGFGSPGTPPPPSP----P 353
G PP P PG PP PP PPPPP+ +GIPPPPP G G P PPPP P P
Sbjct: 1073 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIP--PPPPLPGAGIP 1130
Query: 354 SFPPHPDFAAPPP--------PPPPPAADYPTLPPPPLSQPTGGAPPPPP------PPPP 399
PP P PPP PPPPP PPPPL P G PPPPP PPPP
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGVGIPPPP 1188
Query: 400 P-----GPPPPPFTGADGQPAIPPPLSDTTKPKSSLP 431
P PPPPP GA P PPPL P + P
Sbjct: 1189 PLPGVGIPPPPPLPGAGIPP--PPPLPGMGIPPAPAP 1223
Score = 135 bits (339), Expect = 1e-31
Identities = 93/220 (42%), Positives = 99/220 (45%), Gaps = 47/220 (21%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP + P P +PPPP P+ G+G+ P PPP P
Sbjct: 977 PPPPLPGAGIPPPPPLPGAGIPPPP-----PLP---GAGIPPPPPLPGAGIPPPPPLPGA 1028
Query: 307 G-SPPGPKPGFAPPPAPP------PPPPPM--IGIPPPPPPVGFGSPGTPPPPSP----P 353
G PP P PG PP PP PPPPP+ GIPPPPP G G P PPPP P P
Sbjct: 1029 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIP 1086
Query: 354 SFPPHPDFAAPPP--------PPPPPAADYPTLPPPPLSQPTGGAPPPPP------PPPP 399
PP P PPP PPPPP PPPPL P G PPPPP PPPP
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPP 1144
Query: 400 P-----GPPPPPFTGADGQPAIPPPLSDT-TKPKSSLPAV 433
P PPPPP GA P PPPL P LP V
Sbjct: 1145 PLPRVGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGV 1182
Score = 134 bits (336), Expect = 3e-31
Identities = 89/198 (44%), Positives = 95/198 (47%), Gaps = 39/198 (19%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP + P P +PPPP P+ G+G+ P PPP P
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPP-----PLP---GAGIPPPPPLPGAGIPPPPPLPGA 1094
Query: 307 GSPPGPK-PGFAPPPAPP------PPPPPM--IGIPPPPPPVGFGSPGTPPPPSP----P 353
G PP P PG PP PP PPPPP+ GIPPPPP G G P PPPP P P
Sbjct: 1095 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPRVGIP 1152
Query: 354 SFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPP------PPPPP-----GP 402
PP P A PPPPP P A P PPPPL P G PPPPP PPPPP P
Sbjct: 1153 PPPPLPG-AGIPPPPPLPGAGIP--PPPPL--PGVGIPPPPPLPGVGIPPPPPLPGAGIP 1207
Query: 403 PPPPFTGADGQPAIPPPL 420
PPPP G PA PPL
Sbjct: 1208 PPPPLPGMGIPPAPAPPL 1225
Score = 133 bits (335), Expect = 3e-31
Identities = 100/241 (41%), Positives = 109/241 (45%), Gaps = 38/241 (15%)
Query: 222 SGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPS---FSEDNLPPP-PAEFSYP 277
+G PP I + + + PPPP A+ P P + LPPP P P
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP 977
Query: 278 VDNQRGSGLAGPKRSSVVSPSHPPPAPPLG-SPPGPKPGFAPPPAPP------PPPPPM- 329
G+G+ P PPP P G PP P PG PP PP PPPPP+
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037
Query: 330 -IGIPPPPPPVGFGSPGTPPPPSP----PSFPPHPDFAAPPPPPPPPAADYPTLPPPPLS 384
GIPPPPP G G P PPPP P P PP P A PPPPP P A P PPPPL
Sbjct: 1038 GAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIP--PPPPL- 1091
Query: 385 QPTGGAPPPPP------PPPPP-----GPPPPPFTGADGQPAIPPPLSDT-TKPKSSLPA 432
P G PPPPP PPPPP PPPPP GA P PPPL P LP
Sbjct: 1092 -PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPR 1148
Query: 433 V 433
V
Sbjct: 1149 V 1149
Score = 133 bits (335), Expect = 3e-31
Identities = 82/199 (41%), Positives = 90/199 (45%), Gaps = 32/199 (16%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP + P P +PPPP P+ G+G+ P V PPP P
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPP-----PLP---GAGIPPPPPLPGVGIPPPPPLPGA 1116
Query: 307 GSPPGPK---PGFAPPP------APPPPPPPMIGIPPPPPPVGFGSPGTPPPPSP----P 353
G PP P G PPP PPPPP P +GIPPPPP G G P PPPP P P
Sbjct: 1117 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP--PPPPLPGAGIP 1174
Query: 354 SFPPHPDFAAPPPP-------PPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGP--PP 404
PP P PPPP PPPP +PPPP G P P PP PPPG PP
Sbjct: 1175 PPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP 1234
Query: 405 PPFTGADGQPAIPPPLSDT 423
PP G P +P S T
Sbjct: 1235 PPLLPVSGPPLLPQVGSST 1253
Score = 130 bits (326), Expect = 4e-30
Identities = 90/212 (42%), Positives = 94/212 (44%), Gaps = 41/212 (19%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP A P P PP P P+ G+G+ P + PPP P
Sbjct: 910 PPPPPLPGAGIPPP-------PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA 962
Query: 307 GSP-PGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSP----PSFPPHPDF 361
G P P P PG PPPPP P GIPPPPP G G P PPPP P P PP P
Sbjct: 963 GIPLPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPLPGA 1017
Query: 362 AAPPPP--------PPPPAADYPTLPPPPLSQPTGGAPPPPP------PPPPP-----GP 402
PPPP PPPP PPPPL P G PPPPP PPPPP P
Sbjct: 1018 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIP 1075
Query: 403 PPPPFTGADGQPAIPPPLSDT-TKPKSSLPAV 433
PPPP GA P PPPL P LP V
Sbjct: 1076 PPPPLPGAGIPP--PPPLPGAGIPPPPPLPGV 1105
Score = 118 bits (296), Expect = 1e-26
Identities = 76/189 (40%), Positives = 84/189 (44%), Gaps = 34/189 (17%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP P P +PPPP P+ G+G+ P PPP P +
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPP-----PLP---GAGIPPPPPLPGAGIPPPPPLPRV 1149
Query: 307 GSPPGPK---PGFAPPPA------PPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPP 357
G PP P G PPP PPPPP P +GIPPPPP G G P PPPP P
Sbjct: 1150 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIP--PPPPLPG---- 1203
Query: 358 HPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPA-- 415
A PPPPP P P P PPL P G PPPP P GPP P G+ P
Sbjct: 1204 ----AGIPPPPPLPGMGIPPAPAPPL-PPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258
Query: 416 ----IPPPL 420
+PPPL
Sbjct: 1259 VCGFLPPPL 1267
Score = 113 bits (283), Expect = 3e-25
Identities = 82/197 (41%), Positives = 86/197 (43%), Gaps = 41/197 (20%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPP--PAP 304
PPP +SS P PPPP G+ P S P PP
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLP-----------GMTVPTLPSTAIPQPPPLQGTE 906
Query: 305 PLGSPPGPKPGFAPPPAPPPPP------PPMIGIPPPPPPVGFGSPGTPPPPSP----PS 354
L PP P PG PP PP P PP+ G PPPP G+ PPPP P P
Sbjct: 907 MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL 966
Query: 355 FPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPP------PPPPP-----GPP 403
PP P A PPPPP P A P PPPPL P G PPPPP PPPPP PP
Sbjct: 967 PPPLPG-AGIPPPPPLPGAGIP--PPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1021
Query: 404 PPPFTGADGQPAIPPPL 420
PPP GA P PPPL
Sbjct: 1022 PPPLPGAGIPP--PPPL 1036
Score = 109 bits (273), Expect = 5e-24
Identities = 85/219 (38%), Positives = 93/219 (42%), Gaps = 55/219 (25%)
Query: 245 SYPPPPQSD--SASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPP 302
S PPPP S SA P PP S ++ ++S PS PP
Sbjct: 808 SQPPPPPSLLWSAGQGQPGSQ------PPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL 861
Query: 303 APPLGSPPGPKPGFAPPPAPP--------------PPPPPMIG---IPPPPPPV-GFGSP 344
S P G PPP PP P PPP+ G +PPPPPP+ G G P
Sbjct: 862 PCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIP 921
Query: 345 GTPPPPSPPS----FPPHPDFAAPPPPPPPPAADYPTLP--------PPPLSQPTGGAPP 392
PPPP P + PP P PPPPP P AA P P PPPL P G PP
Sbjct: 922 --PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPL--PGAGIPP 977
Query: 393 PPP------PPPPP-----GPPPPPFTGADGQPAIPPPL 420
PPP PPPPP PPPPP GA P PPPL
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPL 1014
Score = 99.8 bits (247), Expect = 5e-21
Identities = 67/171 (39%), Positives = 76/171 (44%), Gaps = 33/171 (19%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP + P P +PPPP P+ G+G+ P V PPP P
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPP-----PLP---GAGIPPPPPLPRVGIPPPPPLPGA 1160
Query: 307 GSPPGPK-PGFAPPPAPP------PPPPPM--IGIPPPPPPVGFGSP--------GTPPP 349
G PP P PG PP PP PPPPP+ +GIPPPPP G G P G PP
Sbjct: 1161 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPA 1220
Query: 350 PSPPSFPPHPDFAAPPPPPPPPAADYPTLPPP-----PLSQPTGGAPPPPP 395
P+PP PP PPPP P + P LP P Q G PPP P
Sbjct: 1221 PAPPLPPPGTGI---PPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 79.0 bits (193), Expect = 1e-14
Identities = 72/226 (31%), Positives = 85/226 (37%), Gaps = 56/226 (24%)
Query: 231 QNGSIGCVENVDASSYPPPPQSDSASSPSPSF-SEDNLPPPPAEFSYPVDNQRGSGLAGP 289
+ G + + VD PP + S P F SE +L P S +D+ + +
Sbjct: 750 EEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQ---- 805
Query: 290 KRSSVVSPSHPPPAPPLGSPPGP-KPGFAPPPA-----------------------PPPP 325
S S PPP P L G +PG PP + P PP
Sbjct: 806 ------SISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP 859
Query: 326 PPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQ 385
P P P +G P PPPP P P A P PPP + PPPPL
Sbjct: 860 PLPCTESSSSMPGLGMVPP--PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP- 916
Query: 386 PTGGAPPPPPP---------PPPPG---PPPPPFTGADGQPAIPPP 419
G PPPPP PP PG PPPPP GA AIPPP
Sbjct: 917 --GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGA----AIPPP 956
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/189 (33%), Positives = 73/189 (38%), Gaps = 58/189 (30%)
Query: 301 PPAPPLGSPPGPKPGFAPPPA------------PPPPPPPMIGIPPPPPPV----GFGSP 344
PP PP G+ GP+ F + P I PPPPP + G G P
Sbjct: 767 PPCPP-GAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQP 825
Query: 345 GTPPP-------------------------PSPPSFPPHPDFAA-------PPPPPPPPA 372
G+ PP PSPP P ++ PPPPPP P
Sbjct: 826 GSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPG 885
Query: 373 ADYPTLP------PPPLSQPTGGAPPPPPPPPPPG-PPPPPFTGADGQPAIPPPLSDTTK 425
PTLP PPPL Q T PPPPPP P G PPPPP GA P +PP
Sbjct: 886 MTVPTLPSTAIPQPPPL-QGTEMLPPPPPPLPGAGIPPPPPLPGAGILP-LPPLPGAGIP 943
Query: 426 PKSSLPAVS 434
P LP +
Sbjct: 944 PPPPLPGAA 952
Score = 57.4 bits (137), Expect = 3e-08
Identities = 49/151 (32%), Positives = 54/151 (35%), Gaps = 46/151 (30%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP + P P +PPPP P+ G G+ P V PPP P
Sbjct: 1153 PPPPLPGAGIPPPPPLPGAGIPPPP-----PLP---GVGIPPPPPLPGVGIPPPPPLPGA 1204
Query: 307 GSPPGPK-PGFAPPPAPPPP-PPPMIGIPPP----------------------------- 335
G PP P PG PPAP PP PPP GIPPP
Sbjct: 1205 GIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLP 1264
Query: 336 -PPPVG-FG-----SPGTPPPPSPPSFPPHP 359
P P G FG G+ P P P P
Sbjct: 1265 PPLPSGLFGLGMNQDKGSRKQPIEPCRPMKP 1295
Score = 29.3 bits (64), Expect = 8.7
Identities = 41/184 (22%), Positives = 52/184 (28%), Gaps = 31/184 (16%)
Query: 286 LAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIP-------PPPPP 338
L GP + +P P L + A P P PP G+P P P
Sbjct: 253 LLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQP 312
Query: 339 VGFGSPGTPPPPSPPSFPPHPDFAAP-----------------PPPPPPPAADYPTLPPP 381
SP + P P + P AP P P ++
Sbjct: 313 AAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGE 372
Query: 382 PLSQPTG-------GAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVS 434
Q G P P PG P P P I P TT + S P S
Sbjct: 373 DAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHS 432
Query: 435 DARS 438
++S
Sbjct: 433 PSQS 436
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 134 bits (337), Expect = 2e-31
Identities = 97/296 (32%), Positives = 122/296 (41%), Gaps = 75/296 (25%)
Query: 229 VYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAG 288
+ + G + V+N PPPP P P PPPP P
Sbjct: 259 IEKTGGVEAVKNELRRQAPPPPPPSRGGPPPP-------PPPPHNSGPP----------- 300
Query: 289 PKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPP--PMIGIPPPPPPVGFGSPGT 346
PPPA G+PP P P AP APPPPPP P + +PPPPP +
Sbjct: 301 -----------PPPARGRGAPP-PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMY----P 344
Query: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406
PPPP+ PS P + PPPPPP P PPPP PPPPP GPPPPP
Sbjct: 345 PPPPALPSSAP----SGPPPPPPSVLGVGPVAPPPP------PPPPPPP-----GPPPPP 389
Query: 407 FTGADGQPAIPPPLSDTTK--------------PKSSLPAVSDARSDLLSAIRQGFQLRR 452
+DG +P + ++S P R LL IRQG QL+
Sbjct: 390 GLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKS 449
Query: 453 VEEQREQ------EKRDVVGNDVATILSRRIAVEYSD---SEDDSSEF-DEDDWSD 498
V + +E +VG + + R A+ SD EDD +F D+D+W D
Sbjct: 450 VADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED 505
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 124 bits (310), Expect = 3e-28
Identities = 80/201 (39%), Positives = 91/201 (45%), Gaps = 32/201 (15%)
Query: 320 PAPPPPPPPMIGIPPPPPPVGFGSPG------------TPPPPSPPSFPPHPDFAAPPPP 367
P PPPPPP G P PP+ G+ G PPPP+P PP P PPPP
Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG-PPPPGRGGPPPP 370
Query: 368 PPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPK 427
PPP LPPPP P G PP PPPPPPP PPP + G PPPL P
Sbjct: 371 PPPATGRSGPLPPPP---PGAGGPPMPPPPPPPPPPP-----SSGNGPAPPPLPPALVPA 422
Query: 428 SSLPAVSDARSDLLSAIRQGFQLRRVEEQRE--------QEKRDVVGNDVATILSRRIAV 479
L A R LL IRQG QL + E Q +VG + + R A+
Sbjct: 423 GGL-APGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAI 481
Query: 480 EYSD-SEDDSSEFDEDD-WSD 498
SD ED + + DEDD W D
Sbjct: 482 HSSDEGEDQAGDEDEDDEWDD 502
Score = 56.2 bits (134), Expect = 7e-08
Identities = 36/93 (38%), Positives = 39/93 (41%), Gaps = 36/93 (38%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP P P PPPPA +G +GP PPP P
Sbjct: 359 PPPPGR---GGPPP-------PPPPA-----------TGRSGPL---------PPPPPGA 388
Query: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPV 339
G PP PPP PPPPPPP G P PPP+
Sbjct: 389 GGPP------MPPPPPPPPPPPSSGNGPAPPPL 415
Score = 39.3 bits (90), Expect = 0.008
Identities = 33/99 (33%), Positives = 36/99 (36%), Gaps = 41/99 (41%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPP S P PPPP G GP P PPP PP
Sbjct: 371 PPPATGRSGPLP---------PPPP-------------GAGGP-------PMPPPPPPP- 400
Query: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPG 345
PP P G PAPPP PP ++ P G +PG
Sbjct: 401 --PPPPSSGNG--PAPPPLPPALV-------PAGGLAPG 428
Score = 30.0 bits (66), Expect = 5.1
Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 8/69 (11%)
Query: 332 IPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLP---PPPLSQPTG 388
+PPPP P G PP P HP PP P + T+ P S
Sbjct: 159 LPPPPTPANEERRGGLPP-----LPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYR 213
Query: 389 GAPPPPPPP 397
G P P P P
Sbjct: 214 GLPAPGPSP 222
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 118 bits (296), Expect = 1e-26
Identities = 79/204 (38%), Positives = 93/204 (45%), Gaps = 41/204 (20%)
Query: 243 ASSYPPPPQSDSASSPSPSFSEDN---LPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH 299
A + PP S + P+P D+ +PPPPA P D+ +P
Sbjct: 560 AITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPA----PGDS--------------TTPPP 601
Query: 300 PPPAPPLGSPPGPKPG---FAPPPAPP-----PPPPPMIG---IPPPPP-PVGFGSPGTP 347
PPP PP PP P PG + PP+ P PPPP+ G IPPPPP P G G P
Sbjct: 602 PPPPPP---PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 658
Query: 348 PPPSPPSFPPHPDF--AAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG---P 402
P + PP P +A PPPPPP +PPPP P PPPPPP P G P
Sbjct: 659 SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP 718
Query: 403 PPPPFTGADGQPAIPPPLSDTTKP 426
PPPPF G G P PP + P
Sbjct: 719 PPPPFPGGPGIPPPPPGMGMPPPP 742
Score = 116 bits (290), Expect = 5e-26
Identities = 79/184 (42%), Positives = 86/184 (46%), Gaps = 30/184 (16%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP------ 300
PPP DS + P P PPPP V L G + +SP P
Sbjct: 589 PPPAPGDSTTPPPPPPP----PPPPPPLPGGVCISSPPSLPG---GTAISPPPPLSGDAT 641
Query: 301 -PPAPPLGSPPG-PKPGFAPPPAPPPPPPPMIG---IPPPPPPVGFGSPGTPPPPSPPSF 355
PP PPL G P P P PPPPP+ G IPPPPPP+ GS G PPPP
Sbjct: 642 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-GSAGIPPPP----- 695
Query: 356 PPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG-PPPPPF-TGADGQ 413
PP P A PPPPPP P +PPPP P G P PPPPP G PPPPPF G
Sbjct: 696 PPLPGEAGMPPPPPPLPGG-PGIPPPP---PFPGGPGIPPPPPGMGMPPPPPFGFGVPAA 751
Query: 414 PAIP 417
P +P
Sbjct: 752 PVLP 755
Score = 62.0 bits (149), Expect = 1e-09
Identities = 46/122 (37%), Positives = 50/122 (40%), Gaps = 37/122 (30%)
Query: 323 PPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP 382
PP P +PP PP G PPPP+P D PPPPPPPP PP
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPG------DSTTPPPPPPPP---------PP 608
Query: 383 LSQPTGGAPPPPP-------PPPPPG----PPPPPFTGADGQPAIPPPLSDTT--KPKSS 429
PPP P PP PG PPPP +G D PPPL + SS
Sbjct: 609 --------PPPLPGGVCISSPPSLPGGTAISPPPPLSG-DATIPPPPPLPEGVGIPSPSS 659
Query: 430 LP 431
LP
Sbjct: 660 LP 661
Score = 55.8 bits (133), Expect = 9e-08
Identities = 46/127 (36%), Positives = 50/127 (39%), Gaps = 28/127 (22%)
Query: 242 DASSYPPPPQSDSASSPSPSFSEDN--LPPPP-----AEFSYPVDNQRGS-GLAGPKRSS 293
DA+ PPPP + PSPS +PPPP A P GS G+ P
Sbjct: 639 DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL 698
Query: 294 VVSPSHPPPAPPLGSPPG--PKPGFAP----PPAPP----PPPPPMIGIPPPPPPVGFGS 343
PPP PPL PG P P F PP PP PPPPP GFG
Sbjct: 699 PGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPF----------GFGV 748
Query: 344 PGTPPPP 350
P P P
Sbjct: 749 PAAPVLP 755
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 118 bits (296), Expect = 1e-26
Identities = 79/204 (38%), Positives = 93/204 (45%), Gaps = 41/204 (20%)
Query: 243 ASSYPPPPQSDSASSPSPSFSEDN---LPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH 299
A + PP S + P+P D+ +PPPPA P D+ +P
Sbjct: 569 AITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPA----PGDS--------------TTPPP 610
Query: 300 PPPAPPLGSPPGPKPG---FAPPPAPP-----PPPPPMIG---IPPPPP-PVGFGSPGTP 347
PPP PP PP P PG + PP+ P PPPP+ G IPPPPP P G G P
Sbjct: 611 PPPPPP---PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667
Query: 348 PPPSPPSFPPHPDF--AAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG---P 402
P + PP P +A PPPPPP +PPPP P PPPPPP P G P
Sbjct: 668 SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP 727
Query: 403 PPPPFTGADGQPAIPPPLSDTTKP 426
PPPPF G G P PP + P
Sbjct: 728 PPPPFPGGPGIPPPPPGMGMPPPP 751
Score = 116 bits (290), Expect = 5e-26
Identities = 79/184 (42%), Positives = 86/184 (46%), Gaps = 30/184 (16%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP------ 300
PPP DS + P P PPPP V L G + +SP P
Sbjct: 598 PPPAPGDSTTPPPPPPP----PPPPPPLPGGVCISSPPSLPG---GTAISPPPPLSGDAT 650
Query: 301 -PPAPPLGSPPG-PKPGFAPPPAPPPPPPPMIG---IPPPPPPVGFGSPGTPPPPSPPSF 355
PP PPL G P P P PPPPP+ G IPPPPPP+ GS G PPPP
Sbjct: 651 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-GSAGIPPPP----- 704
Query: 356 PPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG-PPPPPF-TGADGQ 413
PP P A PPPPPP P +PPPP P G P PPPPP G PPPPPF G
Sbjct: 705 PPLPGEAGMPPPPPPLPGG-PGIPPPP---PFPGGPGIPPPPPGMGMPPPPPFGFGVPAA 760
Query: 414 PAIP 417
P +P
Sbjct: 761 PVLP 764
Score = 62.0 bits (149), Expect = 1e-09
Identities = 46/122 (37%), Positives = 50/122 (40%), Gaps = 37/122 (30%)
Query: 323 PPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP 382
PP P +PP PP G PPPP+P D PPPPPPPP PP
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPG------DSTTPPPPPPPP---------PP 617
Query: 383 LSQPTGGAPPPPP-------PPPPPG----PPPPPFTGADGQPAIPPPLSDTT--KPKSS 429
PPP P PP PG PPPP +G D PPPL + SS
Sbjct: 618 --------PPPLPGGVCISSPPSLPGGTAISPPPPLSG-DATIPPPPPLPEGVGIPSPSS 668
Query: 430 LP 431
LP
Sbjct: 669 LP 670
Score = 55.8 bits (133), Expect = 9e-08
Identities = 46/127 (36%), Positives = 50/127 (39%), Gaps = 28/127 (22%)
Query: 242 DASSYPPPPQSDSASSPSPSFSEDN--LPPPP-----AEFSYPVDNQRGS-GLAGPKRSS 293
DA+ PPPP + PSPS +PPPP A P GS G+ P
Sbjct: 648 DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL 707
Query: 294 VVSPSHPPPAPPLGSPPG--PKPGFAP----PPAPP----PPPPPMIGIPPPPPPVGFGS 343
PPP PPL PG P P F PP PP PPPPP GFG
Sbjct: 708 PGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPF----------GFGV 757
Query: 344 PGTPPPP 350
P P P
Sbjct: 758 PAAPVLP 764
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 110 bits (275), Expect = 3e-24
Identities = 74/211 (35%), Positives = 93/211 (44%), Gaps = 19/211 (9%)
Query: 210 QEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPP 269
+E VE + P LV + S+ N+D S PQ+ + PS + P
Sbjct: 335 EEVVERLLSVKGRPRPSPLVKAHKSVQA--NLDQSQRGSSPQNTTTPKPSVEGQQ----P 388
Query: 270 PPAEFSYPVDNQRGSGL---AGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPP 326
A PVD+ + + + P+ + + PPP PP P P PPP PPPPP
Sbjct: 389 AAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPP---PLLPGSSAEPPPPPPPPP 445
Query: 327 PPMIGI------PPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPP 380
P +G PPPPP G G+ P PP PP P +F PPPPPP P P PP
Sbjct: 446 LPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFL-PPPPPPLPGLGCPPPPP 504
Query: 381 PPLSQPTGGAPPPPPPPPPPGPPPPPFTGAD 411
P L G PPPPPP P PP G +
Sbjct: 505 PLLPGMGWGPPPPPPPLLPCTCSPPVAGGME 535
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 110 bits (275), Expect = 3e-24
Identities = 74/211 (35%), Positives = 93/211 (44%), Gaps = 19/211 (9%)
Query: 210 QEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPP 269
+E VE + P LV + S+ N+D S PQ+ + PS + P
Sbjct: 335 EEVVERLLSVKGRPRPSPLVKAHKSVQA--NLDQSQRGSSPQNTTTPKPSVEGQQ----P 388
Query: 270 PPAEFSYPVDNQRGSGL---AGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPP 326
A PVD+ + + + P+ + + PPP PP P P PPP PPPPP
Sbjct: 389 AAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPP---PLLPGSSAEPPPPPPPPP 445
Query: 327 PPMIGI------PPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPP 380
P +G PPPPP G G+ P PP PP P +F PPPPPP P P PP
Sbjct: 446 LPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFL-PPPPPPLPGLGCPPPPP 504
Query: 381 PPLSQPTGGAPPPPPPPPPPGPPPPPFTGAD 411
P L G PPPPPP P PP G +
Sbjct: 505 PLLPGMGWGPPPPPPPLLPCTCSPPVAGGME 535
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 108 bits (269), Expect = 1e-23
Identities = 69/183 (37%), Positives = 80/183 (43%), Gaps = 23/183 (12%)
Query: 241 VDASSYP----PPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRG--SGLAGPKRSSV 294
VDA+ P PPP + P PPPP+ + + SG S+
Sbjct: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSM 450
Query: 295 VSPSHPP--PAPPLGSPPGPKPG----FAPPPAPPPPPPPMIGIPPP--PPPVGFGSPGT 346
+ P PP PP P + P P PPP PPP PPP PPP +PG
Sbjct: 451 MKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPP----TPGY 506
Query: 347 PPPPSP--PSFPPHPDFAAPP---PPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG 401
PPPP P+FPP P P PP PPP P PP + P GG PP PPP PPPG
Sbjct: 507 PPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPG 566
Query: 402 PPP 404
PP
Sbjct: 567 MPP 569
Score = 100 bits (249), Expect = 3e-21
Identities = 83/283 (29%), Positives = 96/283 (33%), Gaps = 103/283 (36%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRG-----SGLAGPKRSSVVSPSHP- 300
P QS + S PS + P PA+ P + S KR+ VVSP
Sbjct: 286 PQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEEN 345
Query: 301 -----------------PPAPPLGSPPGPKPGFA----------------------PPPA 321
PP PP PP KP A PPPA
Sbjct: 346 KAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPA 405
Query: 322 PPPP---PPPMIGIPPPPPPVGF--GSPGT--------------------------PPPP 350
P P PPP+ PPPPPP + G T PP
Sbjct: 406 HPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAY 465
Query: 351 SPPSFPPHPDFAAPPPPPPPPAADYP-TLPPPPLSQPTGGAPPPPP------PPPPPGPP 403
PP+ P+ PP PPPPP P + PPP + PT G PPPPP PPPPP P
Sbjct: 466 GPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP 525
Query: 404 --------------------PPPFTGADGQPAIPPPLSDTTKP 426
PPP GQP +PPP+ P
Sbjct: 526 PTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMP 568
Score = 57.8 bits (138), Expect = 2e-08
Identities = 35/95 (36%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Query: 246 YPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPP 305
YPP P P SF +PPP + P + P R P P P
Sbjct: 478 YPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPG 537
Query: 306 LGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVG 340
LG PP P A PP PP PP I PP PPVG
Sbjct: 538 LGLPPASYPPPAVPPGGQPPVPPPIP-PPGMPPVG 571
Score = 47.0 bits (110), Expect = 4e-05
Identities = 35/131 (26%), Positives = 40/131 (30%), Gaps = 21/131 (16%)
Query: 318 PPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPT 377
PP P P P + P S + P P P A P P P P
Sbjct: 276 PPSLQPTPQVPQVQQSQPSQ----SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPR 331
Query: 378 L-----------------PPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL 420
PPPP PP PP PP PP A G+ P P+
Sbjct: 332 QVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPV 391
Query: 421 SDTTKPKSSLP 431
T PK +P
Sbjct: 392 DATDLPKVQIP 402
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 105 bits (262), Expect = 1e-22
Identities = 51/114 (44%), Positives = 55/114 (48%), Gaps = 13/114 (11%)
Query: 299 HPPPAPPLGSPPGPKPGFAPPPAPPPPPPPM------IGIPPPPPPVGFGSPGTPPPPSP 352
H P G + PPPA PPPPP+ + PP PPV G P PPPP P
Sbjct: 628 HAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPP 687
Query: 353 PSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406
P PP PPPPPPPP + P P P G PPP PPPP PPPPP
Sbjct: 688 PPLPPPSSAGPPPPPPPPPLPNSPAPPNP-------GGPPPAPPPPGLAPPPPP 734
Score = 93.2 bits (230), Expect = 5e-19
Identities = 57/129 (44%), Positives = 62/129 (48%), Gaps = 17/129 (13%)
Query: 292 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
SS+ S P + + P G A PPPP PPPP P G GS +P PP
Sbjct: 613 SSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSL-SPAPPM 671
Query: 352 PPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTG-GAPPPPPPPPPPGPPPPPFTGA 410
PP A PP PPPPP PPPPL P+ G PPPPPPPP P P PP G
Sbjct: 672 PPVS------AGPPLPPPPP-------PPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPG- 717
Query: 411 DGQPAIPPP 419
G P PPP
Sbjct: 718 -GPPPAPPP 725
Score = 91.3 bits (225), Expect = 2e-18
Identities = 60/164 (36%), Positives = 67/164 (40%), Gaps = 30/164 (18%)
Query: 247 PPPPQSDSASSPSP-----SFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPP 301
PP D ++ P S + LPPPPA P G G P P
Sbjct: 620 PPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPA----------P 669
Query: 302 PAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDF 361
P PP+ A PP PPPPPPP PP PPP G P PPPP P+ P P+
Sbjct: 670 PMPPVS---------AGPPLPPPPPPP----PPLPPPSSAGPPPPPPPPPLPNSPAPPNP 716
Query: 362 AAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPP 405
PPP PPPP P PPP L G + P P P P
Sbjct: 717 GGPPPAPPPPGLAPP--PPPGLFFGLGSSSSQCPRKPAIEPSCP 758
Score = 68.6 bits (166), Expect = 1e-11
Identities = 33/73 (45%), Positives = 40/73 (54%), Gaps = 3/73 (4%)
Query: 354 SFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQ 413
+ PP P A+ PPPPP P+ P PP+ P PP PPPPPPP P PPP +
Sbjct: 644 ALPPPP--ASIPPPPPLPSGLGSLSPAPPMP-PVSAGPPLPPPPPPPPPLPPPSSAGPPP 700
Query: 414 PAIPPPLSDTTKP 426
P PPPL ++ P
Sbjct: 701 PPPPPPLPNSPAP 713
Score = 53.9 bits (128), Expect = 3e-07
Identities = 48/144 (33%), Positives = 53/144 (36%), Gaps = 46/144 (31%)
Query: 225 PPTLVYQNGSIGC---VENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQ 281
PP L GS+ + V A PPP P PS + PPP
Sbjct: 655 PPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPP----------- 703
Query: 282 RGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPP--- 338
PPP P SP P PG PPPAPPPP G+ PPPPP
Sbjct: 704 ------------------PPPLP--NSPAPPNPG-GPPPAPPPP-----GLAPPPPPGLF 737
Query: 339 VGFGSPGTPPPPSP---PSFPPHP 359
G GS + P P PS P P
Sbjct: 738 FGLGSSSSQCPRKPAIEPSCPMKP 761
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 103 bits (258), Expect = 3e-22
Identities = 67/177 (37%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 254 SASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLA----GPKRS--------SVVSPSH-- 299
S P P + P P+ V+ GL GP + +V +PS
Sbjct: 456 SRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGD 515
Query: 300 -PPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPH 358
P P P GSP P AP P P P PPPPP G SP PP +PP PP
Sbjct: 516 APTPGVPTGSP---SPDLAPAAEPAPGAAP----PPPPPLPGLPSPQEAPPSAPPQAPPL 568
Query: 359 PDFAAPPPPPPPPAADYPTLPPPPLSQPTGGA--PPPPPPPPPPGPPPPPFTGADGQ 413
P PPP PP P P PPPP T G PPPPPPPPPPG PP D +
Sbjct: 569 PGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSE 625
Score = 35.8 bits (81), Expect = 0.093
Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 3/85 (3%)
Query: 239 ENVDASSYPPPPQSDSASSP--SPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVS 296
E ++ PPPP SP +P + PP P P L P
Sbjct: 535 EPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPP 594
Query: 297 PSHPPPAPPLGSPPGPKPGFAPPPA 321
P P PP PP P PG PP A
Sbjct: 595 PGTDGPVPPPPPPPPPPPG-GPPDA 618
Score = 30.4 bits (67), Expect = 3.9
Identities = 12/21 (57%), Positives = 12/21 (57%)
Query: 385 QPTGGAPPPPPPPPPPGPPPP 405
QP G A PPP P PP P P
Sbjct: 10 QPAGPAAPPPKQPAPPKQPMP 30
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 102 bits (255), Expect = 6e-22
Identities = 76/206 (36%), Positives = 85/206 (41%), Gaps = 41/206 (19%)
Query: 248 PPPQSDSASSP-SP----------SFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVS 296
PPPQ D + SP SP ++ PPPP Q G+ GP
Sbjct: 80 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG--K 137
Query: 297 PSHPPPA--------PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPP 348
P PPP P G P GP P P PPPPP G P PPP G P PP
Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGKKPQGPP 194
Query: 349 PPSPPSFPP---HPDFAAPPPP-----PPPPAADYPTLPPPPLSQPTGGAPPP-----PP 395
PP P PP ++ PP PPP + P PPPP +P G PPP P
Sbjct: 195 PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNKPQ 252
Query: 396 PPPPPGPP--PPPFTGADGQPAIPPP 419
PPPPG P PP G+ Q A PP
Sbjct: 253 GPPPPGKPQGPPAQGGSKSQSARSPP 278
Score = 96.7 bits (239), Expect = 4e-20
Identities = 77/227 (33%), Positives = 88/227 (38%), Gaps = 51/227 (22%)
Query: 226 PTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSG 285
P+L+ N + + PPPP P ++ PPPP + P
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP------- 81
Query: 286 LAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPG 345
P+ SP PP G P GP P P PPPPP G P PPP G P
Sbjct: 82 ---PQGDKSRSPRSPP-----GKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGNRPQ 130
Query: 346 TPPPPSPPSFPP-HPDFAAPP--PP-----PPPPAADYPTLPPPPLSQPTGG-------- 389
PPPP P PP D + P PP PPP + P PPPP +P G
Sbjct: 131 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP 190
Query: 390 -APPPP--P--PPP----------PPGPP--PPPFTGADGQPAIPPP 419
PPPP P PPP PPG P PPP G Q PPP
Sbjct: 191 QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP 237
Score = 94.0 bits (232), Expect = 3e-19
Identities = 71/201 (35%), Positives = 79/201 (39%), Gaps = 41/201 (20%)
Query: 248 PPPQSDSASSPSPSFSEDNLPPP-----PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPP 302
PPPQ D + SP + PPP P P +G G K+ P P
Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200
Query: 303 APPL------------GSPPGPKP-GFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPP 349
PP G P GP P G P PPPPP G P PPP G P PPP
Sbjct: 201 GPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP----GKPQGPPPQGGNKPQGPPP 256
Query: 350 PSPPSFPP----HPDFAAPPPP-----PPPPAADYPTLPPPPLSQPTGGAPPPPPPPP-- 398
P P PP +A PP PP + P PPP P GG P P PP
Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP----PAGGNPQQPQAPPAG 312
Query: 399 -PPGPPPPPFTGADGQPAIPP 418
P GPP PP G+P+ PP
Sbjct: 313 QPQGPPRPP---QGGRPSRPP 330
Score = 82.8 bits (203), Expect = 7e-16
Identities = 55/139 (39%), Positives = 62/139 (44%), Gaps = 21/139 (15%)
Query: 302 PAPPLGSPPGPKPGFA-----PPPAPPPP--PPPMIGIPP--PPPPVGFGSPGTPPPPSP 352
P+ G+P GP P PPP P P PPP G P PPPP G P PPP
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPPQGD 85
Query: 353 PSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADG 412
S P P PPP + P PPPP +P G PPP P GPPPP G
Sbjct: 86 KSRSPRSP-PGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNRPQGPPPP------G 136
Query: 413 QPAIPPPLSDTTKPKSSLP 431
+P PPP D ++ S P
Sbjct: 137 KPQGPPPQGDKSRSPRSPP 155
Score = 79.0 bits (193), Expect = 1e-14
Identities = 60/169 (35%), Positives = 65/169 (38%), Gaps = 21/169 (12%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPV---DNQRGSGLAGPKRSSVVSPSHPPPA 303
PPPP P + PPPP + P D R S +S P PPP
Sbjct: 172 PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS------QSPPGKPQGPPPQ 225
Query: 304 ---PPLGSPPGP-KPGFAPPPA---PPPPPPPMIGIPPPPPPVGFG-SPGTPPPPSPPSF 355
P G PP P KP PP P PPPP G P PP G S PP P
Sbjct: 226 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP--GKPQGPPAQGGSKSQSARSPPGKPQG 283
Query: 356 PPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPP 404
PP + P PPPP + PP QP G PP PP P PP
Sbjct: 284 PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG--PPRPPQGGRPSRPP 330
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 102 bits (253), Expect = 1e-21
Identities = 78/230 (33%), Positives = 85/230 (36%), Gaps = 38/230 (16%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPV---DNQRGSGLA------GPKRSSVVSP 297
PPPP P ++ PPPP + P DN+ S + GP P
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191
Query: 298 SHPPPAP--PLGSPP--GPKPGFAPPPAPPPPPPPM-----------IGIPPPPPPVGFG 342
PPP P P G PP G KP PPP P PPP G P PPP G
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 343 SP-GTPPPPSPPSFPPHPDFAAPPPPPPPPAADYP----------TLPPPPLSQ---PTG 388
P G PPPP P PP P PPPP P + PP Q P G
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQG 311
Query: 389 GAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARS 438
G P PPPPP P PP G + PPP P ARS
Sbjct: 312 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARS 361
Score = 97.4 bits (241), Expect = 3e-20
Identities = 80/227 (35%), Positives = 88/227 (38%), Gaps = 60/227 (26%)
Query: 248 PPPQSDSASSP-SP----------SFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVS 296
PPPQ D + SP SP ++ PPPP Q G+ GP
Sbjct: 101 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--K 158
Query: 297 PSHPPPA---------PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTP 347
P PPP P G P GP P P PPPPP G P PPP G P P
Sbjct: 159 PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGNKPQGP 215
Query: 348 PPPSPPSFPP----HPDFAAPPPP-----PPPPAADYPTLPPPPLSQPTGG--------- 389
PPP P PP + +A PP PPP + P PPPP +P G
Sbjct: 216 PPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 275
Query: 390 APPPP--P--PPP-----------PPGPP--PPPFTGADGQPAIPPP 419
PPPP P PPP PPG P PPP G Q PPP
Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 322
Score = 96.7 bits (239), Expect = 4e-20
Identities = 77/237 (32%), Positives = 89/237 (37%), Gaps = 48/237 (20%)
Query: 226 PTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSG 285
P+L+ N + + PP P P ++ PPPP Q G+
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88
Query: 286 LAGPKRSSVVSPSHPPPA--------PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP 337
GP P PPP P G P GP P P PPPPP G P PP
Sbjct: 89 PQGPPPPG--KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGPP 143
Query: 338 PVGFGSPGTPPPPSPPSFPP----HPDFAAPPPP-----PPPPAADYPTLPPPPLSQPTG 388
P G P PPPP P PP + ++ PP PPP + P PPPP +P G
Sbjct: 144 PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 203
Query: 389 G---------APPPP--P--PPP-----------PPGPP--PPPFTGADGQPAIPPP 419
PPPP P PPP PPG P PPP G Q PPP
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPP 260
Score = 95.5 bits (236), Expect = 1e-19
Identities = 76/217 (35%), Positives = 82/217 (37%), Gaps = 52/217 (23%)
Query: 249 PPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGS 308
PPQ + PS PPP Q G+ GP PPP P G
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPP---------QGGNQPQGPP---------PPPGKPQGP 81
Query: 309 PP--GPKPGFAPPPAPPPPPPPM----------IGIPPPPPPVGFGSP-GTPPPPSPPSF 355
PP G KP PPP P PPP G P PPP G P G PPPP P
Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 141
Query: 356 PPHPDFAAP--PPPP-----PPPAADYPTL----PP--PPLSQPTGGAPPPPPPPPPPGP 402
PP P PPPP PPP D + PP P P GG P PPPPP P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201
Query: 403 PPPPFTGAD--------GQPAIPPPLSDTTKPKSSLP 431
PP G + G+P PPP D + P
Sbjct: 202 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238
Score = 94.4 bits (233), Expect = 2e-19
Identities = 66/184 (35%), Positives = 74/184 (40%), Gaps = 36/184 (19%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPPP P ++ PPPP + P P+ S S PP P
Sbjct: 256 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP----------PQGGSKSRSSRSPPGKPQ 305
Query: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPP----HPDFA 362
G PP G P PPPPP G P PPP G P PPPP P PP +
Sbjct: 306 GPPP---QGGNQPQGPPPPP----GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 358
Query: 363 APPPP-----PPPPAADYPTLPPPPLSQPTGGAPPPPPPPP---PPGPPPPPFTGADGQP 414
A PP PP + P PPP P GG P P PP P GPP PP G+P
Sbjct: 359 ARSPPGKPQGPPQQEGNNPQGPPP----PAGGNPQQPQAPPAGQPQGPPRPP---QGGRP 411
Query: 415 AIPP 418
+ PP
Sbjct: 412 SRPP 415
Score = 87.8 bits (216), Expect = 2e-17
Identities = 58/151 (38%), Positives = 62/151 (41%), Gaps = 24/151 (15%)
Query: 302 PAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSP-GTPPPPSPPSFPPHPD 360
P+ G+P G P P PP PP G P PPP G P G PPPP P PP
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPP---GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 361 FAAP--PPPP-----PPPAADYPTLPPPPLSQPTGGAP--------PPPPPPPPPGPPP- 404
P PPPP PPP D P P +P G P PPPPP P GPPP
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 145
Query: 405 ----PPFTGADGQPAIPPPLSDTTKPKSSLP 431
P G+P PPP D S P
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 101 bits (252), Expect = 1e-21
Identities = 80/225 (35%), Positives = 86/225 (38%), Gaps = 53/225 (23%)
Query: 245 SYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPK-RSSVVSPSHP--- 300
S P P QS + SP P P P RG+ L G R S +S S P
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 301 -PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIP-------PPPPPVGFGSPGTPPPPSP 352
PP P P P A PPPPPPP+ P PPPPP PP PS
Sbjct: 249 RPPLP-------PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP----QNNKPPVPST 297
Query: 353 PSFPPHPDFAAPPPPPPPPAADYPTLPP----------------------PPLSQPTGGA 390
P P APPPPPPP P LPP PPL P
Sbjct: 298 PR--PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355
Query: 391 PPPPPP---PPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPA 432
P PPPP PPPP PP G G PPP+S +LPA
Sbjct: 356 PLPPPPSERPPPPVRDPP---GRSGPLPPPPPVSRNGSTSRALPA 397
Score = 99.4 bits (246), Expect = 7e-21
Identities = 77/223 (34%), Positives = 88/223 (39%), Gaps = 42/223 (18%)
Query: 247 PPPPQSDSASSPSPSFSEDNLP-PPPAEFSYPVDNQRGSGLAGPKRSSVVSP--SHPPPA 303
PP +S SA SP P P P S P + QR P R V S S PPP
Sbjct: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNR--MPPPRPDVGSKPDSIPPPV 187
Query: 304 P----PLGSPPG-----PKPGFAPPPAPPPPPPPMIGIP--------------------- 333
P P+ S P P PG P+P P PPP G
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFS 247
Query: 334 --PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAP 391
PP PP + PPP PP P PPPPP + P +P P + AP
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307
Query: 392 PPPPPPPPPGPP--PPPFTGADGQPAIPP---PLSDTTKPKSS 429
PPPPPP PGPP PP +G D P +P LS +T P S
Sbjct: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350
Score = 92.4 bits (228), Expect = 8e-19
Identities = 76/234 (32%), Positives = 95/234 (40%), Gaps = 48/234 (20%)
Query: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303
S+ PP P P+PS + D+ PPPP PV N R S+ + PPP
Sbjct: 247 SNRPPLP-------PTPSRALDDKPPPPPP---PVGN----------RPSIHREAVPPPP 286
Query: 304 PPLGSPPGPKPGFAPPPAPP---PPPPPMIGIPPPPPPVGFGSPGTPPPPS-----PPSF 355
P PP P P + PPPPP PPP PP G+ TP P S
Sbjct: 287 PQNNKPPVPSTP-RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345
Query: 356 PPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPP-----------PPGPPP 404
PP P P PPPP+ PPPP+ P G + P PPPPP P P
Sbjct: 346 PPLPSPGRSGPLPPPPS----ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL 401
Query: 405 PPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQRE 458
P +G D + P P +P + P ++IR GFQ E++ E
Sbjct: 402 PSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS----TSIRNGFQDSPCEDEWE 451
Score = 55.5 bits (132), Expect = 1e-07
Identities = 56/179 (31%), Positives = 62/179 (34%), Gaps = 35/179 (19%)
Query: 240 NVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH 299
N+ SS PP S S P LPPPP+E P P RS + P
Sbjct: 338 NLSLSSSTPPLPSPGRSGP--------LPPPPSERPPPPVRD------PPGRSGPLPPPP 383
Query: 300 P-----------PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPP 348
P P P L S G + P P PP P G PPPPPP G
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443
Query: 349 PPSPPS----FPPHPDFAAPPPPP-PPPAADYPTLPPPPLSQPTG-----GAPPPPPPP 397
P F HP PPP P YP+ S+ GAPP PP P
Sbjct: 444 SPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 54.3 bits (129), Expect = 3e-07
Identities = 41/119 (34%), Positives = 44/119 (36%), Gaps = 19/119 (15%)
Query: 298 SHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPP 357
S PP PP G KP F+PP P P P G G P P PP
Sbjct: 124 SRPPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPG----------HRSGPPEPQRNRMPPP 172
Query: 358 HPDFAAPPPPPPPPAADYP----TLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADG 412
PD + P PPP P + P S P G P P P P PPPF G G
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT----PPPFPGNRG 227
Score = 33.9 bits (76), Expect = 0.35
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 11/58 (18%)
Query: 395 PPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRR 452
P PPPP PPPPP L++T KP + R+ LLS I +G +L++
Sbjct: 2 PVPPPPAPPPPPTFA----------LANTEKPTLN-KTEQAGRNALLSDISKGKKLKK 48
Score = 33.5 bits (75), Expect = 0.46
Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 19/93 (20%)
Query: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPP----PPP 398
S G+ PP PP +A P PP +P P S PP P PPP
Sbjct: 121 SGGSRPPLLPPG---GRSTSAKPFSPPSGPGRFPVPSPGHRS-----GPPEPQRNRMPPP 172
Query: 399 PPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLP 431
P P +IPPP+ T +P S P
Sbjct: 173 RPDVGSKP-------DSIPPPVPSTPRPIQSSP 198
Score = 30.4 bits (67), Expect = 3.9
Identities = 19/52 (36%), Positives = 22/52 (42%), Gaps = 4/52 (7%)
Query: 391 PPPPPPPPPP----GPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARS 438
PPPP PPPPP P Q LSD +K K V++ RS
Sbjct: 4 PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRS 55
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 101 bits (252), Expect = 1e-21
Identities = 80/225 (35%), Positives = 86/225 (38%), Gaps = 53/225 (23%)
Query: 245 SYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPK-RSSVVSPSHP--- 300
S P P QS + SP P P P RG+ L G R S +S S P
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 301 -PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIP-------PPPPPVGFGSPGTPPPPSP 352
PP P P P A PPPPPPP+ P PPPPP PP PS
Sbjct: 249 RPPLP-------PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP----QNNKPPVPST 297
Query: 353 PSFPPHPDFAAPPPPPPPPAADYPTLPP----------------------PPLSQPTGGA 390
P P APPPPPPP P LPP PPL P
Sbjct: 298 PR--PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355
Query: 391 PPPPPP---PPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPA 432
P PPPP PPPP PP G G PPP+S +LPA
Sbjct: 356 PLPPPPSERPPPPVRDPP---GRSGPLPPPPPVSRNGSTSRALPA 397
Score = 99.4 bits (246), Expect = 7e-21
Identities = 77/223 (34%), Positives = 88/223 (39%), Gaps = 42/223 (18%)
Query: 247 PPPPQSDSASSPSPSFSEDNLP-PPPAEFSYPVDNQRGSGLAGPKRSSVVSP--SHPPPA 303
PP +S SA SP P P P S P + QR P R V S S PPP
Sbjct: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNR--MPPPRPDVGSKPDSIPPPV 187
Query: 304 P----PLGSPPG-----PKPGFAPPPAPPPPPPPMIGIP--------------------- 333
P P+ S P P PG P+P P PPP G
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFS 247
Query: 334 --PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAP 391
PP PP + PPP PP P PPPPP + P +P P + AP
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP 307
Query: 392 PPPPPPPPPGPP--PPPFTGADGQPAIPP---PLSDTTKPKSS 429
PPPPPP PGPP PP +G D P +P LS +T P S
Sbjct: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350
Score = 92.4 bits (228), Expect = 8e-19
Identities = 76/234 (32%), Positives = 95/234 (40%), Gaps = 48/234 (20%)
Query: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303
S+ PP P P+PS + D+ PPPP PV N R S+ + PPP
Sbjct: 247 SNRPPLP-------PTPSRALDDKPPPPPP---PVGN----------RPSIHREAVPPPP 286
Query: 304 PPLGSPPGPKPGFAPPPAPP---PPPPPMIGIPPPPPPVGFGSPGTPPPPS-----PPSF 355
P PP P P + PPPPP PPP PP G+ TP P S
Sbjct: 287 PQNNKPPVPSTP-RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345
Query: 356 PPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPP-----------PPGPPP 404
PP P P PPPP+ PPPP+ P G + P PPPPP P P
Sbjct: 346 PPLPSPGRSGPLPPPPS----ERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL 401
Query: 405 PPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQRE 458
P +G D + P P +P + P ++IR GFQ E++ E
Sbjct: 402 PSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS----TSIRNGFQDSPCEDEWE 451
Score = 55.5 bits (132), Expect = 1e-07
Identities = 56/179 (31%), Positives = 62/179 (34%), Gaps = 35/179 (19%)
Query: 240 NVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH 299
N+ SS PP S S P LPPPP+E P P RS + P
Sbjct: 338 NLSLSSSTPPLPSPGRSGP--------LPPPPSERPPPPVRD------PPGRSGPLPPPP 383
Query: 300 P-----------PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPP 348
P P P L S G + P P PP P G PPPPPP G
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD 443
Query: 349 PPSPPS----FPPHPDFAAPPPPP-PPPAADYPTLPPPPLSQPTG-----GAPPPPPPP 397
P F HP PPP P YP+ S+ GAPP PP P
Sbjct: 444 SPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 54.3 bits (129), Expect = 3e-07
Identities = 41/119 (34%), Positives = 44/119 (36%), Gaps = 19/119 (15%)
Query: 298 SHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPP 357
S PP PP G KP F+PP P P P G G P P PP
Sbjct: 124 SRPPLLPPGGRSTSAKP-FSPPSGPGRFPVPSPG----------HRSGPPEPQRNRMPPP 172
Query: 358 HPDFAAPPPPPPPPAADYP----TLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADG 412
PD + P PPP P + P S P G P P P P PPPF G G
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT----PPPFPGNRG 227
Score = 33.9 bits (76), Expect = 0.35
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 11/58 (18%)
Query: 395 PPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRR 452
P PPPP PPPPP L++T KP + R+ LLS I +G +L++
Sbjct: 2 PVPPPPAPPPPPTFA----------LANTEKPTLN-KTEQAGRNALLSDISKGKKLKK 48
Score = 33.5 bits (75), Expect = 0.46
Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 19/93 (20%)
Query: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPP----PPP 398
S G+ PP PP +A P PP +P P S PP P PPP
Sbjct: 121 SGGSRPPLLPPG---GRSTSAKPFSPPSGPGRFPVPSPGHRS-----GPPEPQRNRMPPP 172
Query: 399 PPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLP 431
P P +IPPP+ T +P S P
Sbjct: 173 RPDVGSKP-------DSIPPPVPSTPRPIQSSP 198
Score = 30.4 bits (67), Expect = 3.9
Identities = 19/52 (36%), Positives = 22/52 (42%), Gaps = 4/52 (7%)
Query: 391 PPPPPPPPPP----GPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARS 438
PPPP PPPPP P Q LSD +K K V++ RS
Sbjct: 4 PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRS 55
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 100 bits (248), Expect = 4e-21
Identities = 81/209 (38%), Positives = 90/209 (43%), Gaps = 48/209 (22%)
Query: 248 PPPQSDSASSPSPSFSEDNLPPP-PAEFSYPVDNQRGSGLAGPKRSSVVSPS-HPPPAPP 305
PP S A+ P P P +P G AGP P+ PP PP
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP-------GPAGPGGPPPPFPAGQTPPRPP 240
Query: 306 LGSPPGPKPGFAPPPAPPPP----PPPMIGIPP----PPPPVGF-GSP-GTPP----PPS 351
LG PPGP PG PP PPPP PPP+ G P PPPPV F G P G PP PP
Sbjct: 241 LG-PPGP-PG---PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG 295
Query: 352 PPSFPPHPDFAAPPPPPPP------PAADYPTLPPPPLSQPTG------------GAPPP 393
PP PP P + PP PPPP P +P PP PL P GAPPP
Sbjct: 296 PP--PPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353
Query: 394 PPPPPPPGPPPPPFTGADGQPAIPPPLSD 422
P P PPP +G + PP +D
Sbjct: 354 APHVNPAFFPPPTNSGMPTSDSRGPPPTD 382
Score = 100 bits (248), Expect = 4e-21
Identities = 66/178 (37%), Positives = 71/178 (39%), Gaps = 15/178 (8%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSS------VVSPSHP 300
PPPP + P P P PP P LAGP V+ P P
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGP--PPPGQVLPPPLAGPPNRGDRPPPPVLFPGQP 283
Query: 301 PPAPPLG----SPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFP 356
PPLG PP P PG+ PPP PPPP G PPPP P PG PP + P
Sbjct: 284 FGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQ---GPPPPPGPFPPRPPGPLGPPLTLAPP 340
Query: 357 PHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQP 414
PH P PPP P + PPP S PPP P G PPP G G P
Sbjct: 341 PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
Score = 95.9 bits (237), Expect = 8e-20
Identities = 65/157 (41%), Positives = 71/157 (45%), Gaps = 18/157 (11%)
Query: 283 GSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFG 342
G+ G + P PPP P G P P+P PP P PP PP G PPP G
Sbjct: 209 GAVPGGDRFPGPAGPGGPPPPFPAGQTP-PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPP 267
Query: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPP----- 397
+ G PPP P FP P F PP P PP PPPP+ P G PP PPPP
Sbjct: 268 NRGDRPPP-PVLFPGQP-FGQPPLGPLPPG------PPPPV--PGYGPPPGPPPPQQGPP 317
Query: 398 PPPGPPPPPFTGADGQP--AIPPPLSDTTKPKSSLPA 432
PPPGP PP G G P PPP P + PA
Sbjct: 318 PPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPA 354
Score = 57.8 bits (138), Expect = 2e-08
Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 17/132 (12%)
Query: 225 PPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGS 284
PP +++ G PPPP P P + PPPP F R
Sbjct: 274 PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFP-----PRPP 328
Query: 285 GLAGPKRSSVVSPSHPPPAPPLGSPPGP--KPGFAPPPAPP---------PPPPPMIGIP 333
G GP + + P H P PP PP P P F PPP PPP G P
Sbjct: 329 GPLGPPLT-LAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP 387
Query: 334 PPPPPVGFGSPG 345
PP +G PG
Sbjct: 388 PPYDRGDYGPPG 399
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/102 (32%), Positives = 36/102 (35%), Gaps = 18/102 (17%)
Query: 340 GFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPP----- 394
G G G P S +FP P P +P P G PPPP
Sbjct: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP-------GGPPPPFPAGQ 234
Query: 395 -PPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSD 435
PP PP GPP PP G P PPP P + P D
Sbjct: 235 TPPRPPLGPPGPP-----GPPGPPPPGQVLPPPLAGPPNRGD 271
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 99.8 bits (247), Expect = 5e-21
Identities = 73/216 (33%), Positives = 87/216 (40%), Gaps = 34/216 (15%)
Query: 248 PPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLG 307
PPPQ+ A + P LP PP Q LA P + SP PP PL
Sbjct: 590 PPPQAPPALASPPL---QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA 646
Query: 308 SPPGPKPG----------FAPPPAPP------PPPPPMIG---IPPPPPPVGFGSPGTPP 348
+P P F+PPP+PP PP P + PP P +P
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 349 PPSPPSFPPHPDFAAPPPPPPPPAADYP--TLPPPPLSQPTGGAPPPPP-------PPPP 399
PPSPP+ PP A PPP PPP A P P PP S P + PPP PP
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 400 PGPPPPPFTGADGQPAIPPPLSD---TTKPKSSLPA 432
PP PP + A PPP + T P +LP+
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802
Score = 95.1 bits (235), Expect = 1e-19
Identities = 86/255 (33%), Positives = 95/255 (37%), Gaps = 85/255 (33%)
Query: 247 PPPPQSDSAS---SPSPS-------------FSEDNLPPPPAEFSYPVDNQRGSGLAGPK 290
P PP S S +PSP FS PP A FS P
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-------------PP 680
Query: 291 RSSVVSPSHPPP--------APPLGSPPGP------KPGFAPPP-APPPPPPPMIGIPPP 335
S VSPS PP APPL PP P P PPP APPP P + +PP
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 336 PP------PVGFGSPGTPP---------PPSPPSFPPHPDFAAPPPPPPPPAADYP--TL 378
PP P P PP PPSPP+ P A PPP PP A P L
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
Query: 379 PPPPLSQPTGGAP--------------PPPPPPP---------PPGPPPPPFTGADGQPA 415
P PP S P G AP PPP PP PP PP P A +P
Sbjct: 801 PSPPASFP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859
Query: 416 IPPPLSDTTKPKSSL 430
P P + + P+ +L
Sbjct: 860 TPGPDTSVSGPRLTL 874
Score = 91.7 bits (226), Expect = 1e-18
Identities = 79/250 (31%), Positives = 102/250 (40%), Gaps = 54/250 (21%)
Query: 225 PPTLVYQNGSIGC--VENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQR 282
PP+L S+ +EN+ + + PPP Q+ SA +P +L PP P+
Sbjct: 520 PPSLQTPPASLTTPPLENLPSLA-PPPLQTASAPLTTP-----HLETPPCPAPCPLQAPP 573
Query: 283 GSGLAGPKR--SSVVSPSHPPPAPP-LGSPPG---PKPGFAPPPAPPPPPPPMIGIPP-- 334
P SS+ +P PP APP L SPP P P +P PPP PP + +PP
Sbjct: 574 SPLTTPPPETPSSIATP--PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ 631
Query: 335 ---------PPPPVGFGSPGTP-------------PPPSPPSFPPHPDFAAPPPPPPPPA 372
P P+ SP P PPPSPP P F+ P PP P+
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP---FSPPASPPVSPS 688
Query: 373 ADYPTLPPPPLSQPTGGAPPPPPPPPP---PGPPPP--------PFTGADGQPAIPPPLS 421
A P+ PP L+ P PP PP PP PPP P P PP+S
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748
Query: 422 DTTKPKSSLP 431
+ P +P
Sbjct: 749 PSATPPPRVP 758
Score = 87.4 bits (215), Expect = 3e-17
Identities = 76/213 (35%), Positives = 86/213 (40%), Gaps = 48/213 (22%)
Query: 241 VDASSYPP--PPQSDSASSPS---PSFSEDNLPPPPAEFSYPVDN-------QRGSGLAG 288
V A PP PP S SA+ PS PS + L PP+ + P + Q LA
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732
Query: 289 PKRSSVVSPSHPPPAPPLGSPPGPKPGF--APPPAPPPPPP------PMIGIPPPPPPVG 340
P SP PP P +PP P APP PP PP P+ PP PP
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP-A 791
Query: 341 FGSPGTPPPPSPP-SFPPHPDFA----------APPPPPPPPAADYPTL--PPPPLSQPT 387
+P PSPP SFP F+ A PPP PP P L PP P + PT
Sbjct: 792 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 388 GGAPPPPPPPPP--------------PGPPPPP 406
AP PP P P PGPPPPP
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884
Score = 84.3 bits (207), Expect = 2e-16
Identities = 69/210 (32%), Positives = 79/210 (37%), Gaps = 30/210 (14%)
Query: 243 ASSYPPPPQSDSASSP---SPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH 299
AS P P S P S + +L PPA + P S P +++ S
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA----SA 551
Query: 300 PPPAPPLGSPPGPKP-GFAPPPAPPPPPPP----MIGIPPPPPPVGFGSPGTPPPPSPPS 354
P P L +PP P P PP+P PPP I PPP P SP PSPP
Sbjct: 552 PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL 611
Query: 355 FPPHPDFAAPPPPPPPPAADYPTL---PPPPLSQPTGGAPPPPPPPP----------PPG 401
P A PPP PP P L P PP S P P P P P
Sbjct: 612 SP-----LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 402 PPPPPFTGADGQPAIPPPLSDTTKPKSSLP 431
PPP P A P PP+S + P S P
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAP 696
Score = 78.6 bits (192), Expect = 1e-14
Identities = 81/257 (31%), Positives = 93/257 (36%), Gaps = 74/257 (28%)
Query: 248 PPPQSDSASSPSPSFSEDNLPPP--PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPP 305
PP Q + SP S PPP P + P S A S + P PP APP
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP--PPQAPP 790
Query: 306 ---------LGSPPGPKPGFAP--PPA---------PPPPPPPMIGIP----PPPPPVG- 340
L SPP PG AP P A PPP PP++ P PP PP
Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850
Query: 341 -FGSPGTPPPPSPPSFPPHPDFA---APPPPPPPPAADYPTLPPPPL------------- 383
+P PP P P + P AP PPPPP + TL P L
Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910
Query: 384 -----SQPTGGAPPPPPPPP----------PPGPPPP-PFTGADGQPAIPPP-------- 419
S P GGA PPP GP PP F GA G P PP
Sbjct: 911 LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 970
Query: 420 ----LSDTTKPKSSLPA 432
+ +T P+S+ PA
Sbjct: 971 GLCTIYETEGPESATPA 987
Score = 77.8 bits (190), Expect = 2e-14
Identities = 65/199 (32%), Positives = 77/199 (38%), Gaps = 19/199 (9%)
Query: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303
S+ P PP S S + P PA P G GL P S+ S + P +
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP---SAGGGLQRPASRSLSSSATPLSS 251
Query: 304 PPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPP--PPVGFGSPGTPPPPSPPSFPPHPDF 361
P P AP P P + + PP PP +P P S P P P
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311
Query: 362 AAPPPPPPPPAADYP---TLPP-PPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIP 417
P PPP A P TLPP PPL+ P APP P PP P P PA P
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP-------PATP 364
Query: 418 P---PLSDTTKPKSSLPAV 433
P P S TT P + P++
Sbjct: 365 PSQAPPSMTTPPMQAPPSL 383
Score = 73.2 bits (178), Expect = 5e-13
Identities = 59/193 (30%), Positives = 74/193 (38%), Gaps = 6/193 (3%)
Query: 242 DASSYPPPPQSDSASSPSPSFSEDNLPPPP--AEFSYPVDNQRGSGLAGPKRSSVVSPSH 299
DA+ P S ++PSPS ++ PPP A P LA P + SPS
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 300 PPPAPPLGSPPGPKPGFAPPPAPPPP---PPPMIGIPPPPPPVGFGSPGTPPPPSPPSFP 356
PP L SPP P APP PP PP + IPP P SP PPSP +
Sbjct: 351 PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
Query: 357 PHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAI 416
+ P + T+ P +Q + +P P PP PP P +
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQ-TQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469
Query: 417 PPPLSDTTKPKSS 429
LS P SS
Sbjct: 470 QTSLSPAVSPLSS 482
Score = 70.9 bits (172), Expect = 3e-12
Identities = 71/222 (31%), Positives = 82/222 (36%), Gaps = 40/222 (18%)
Query: 248 PPPQSDSASSPS-PSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSP--------- 297
P S +SPS P+ + + PP A S P + L+ P S + SP
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS-PAVSPLSSPLTIHPLQAL 492
Query: 298 ----SHPPPAP--PLGSPPGPKPGFAPPPAPPPPP-----PPMIGIP---PPPPPVGFGS 343
SH P AP L PP PP+ PP PP+ +P PPP
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
Query: 344 PGTPPPPSPPSFPPHPDFAAPPPPPPPP-------AADYPTLPPPPLSQPTGGAPPPPPP 396
TP +PP P P A P P PP A P PP S P G P PP
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS 612
Query: 397 P---PPPGPPP----PPFTGADGQPAIPPPLSDTTKPKSSLP 431
P PPP PP PP PA PPLS P P
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPA-SPPLSPLATPSPQAP 653
Score = 60.5 bits (145), Expect = 4e-09
Identities = 60/205 (29%), Positives = 75/205 (36%), Gaps = 25/205 (12%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PP P + S+ + S L + F Q + L P R + P PP PL
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHS-FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461
Query: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP 366
P P + PA P P+ I P S P S PP ++ P
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLT-IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
Query: 367 P----PP-----PPAADYPTLPPPPLSQPTGGAP--------PPPPPPPPPGPPPPPFTG 409
P PP PP + P+L PPPL T AP PP P P P PP P T
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQ--TASAPLTTPHLETPPCPAPCPLQAPPSPLT- 577
Query: 410 ADGQPAIPPPLSDTTKPKSSLPAVS 434
P P S T P + PA++
Sbjct: 578 ---TPPPETPSSIATPPPQAPPALA 599
Score = 59.3 bits (142), Expect = 8e-09
Identities = 56/173 (32%), Positives = 64/173 (36%), Gaps = 31/173 (17%)
Query: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303
SS P S + S PS P PA S P + GL R V+P A
Sbjct: 243 SSSATPLSSPARSGPSAR----GTPRAPAHPSQP----KPKGLQA-LRPPQVTPPRKDAA 293
Query: 304 PPLG----------SPPGPKPGFAPPP--------APPPPPPPMIGIPPPPPPVGFGSPG 345
P LG SP G K PPP A PP PP+ P PP P
Sbjct: 294 PALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353
Query: 346 TPPPPSPPSFPPH---PDFAAPPPPPPPPAADYPTLP-PPPLSQPTGGAPPPP 394
PSPP+ PP P PP PP P + P L+ P+ APP P
Sbjct: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
Score = 39.3 bits (90), Expect = 0.008
Identities = 51/212 (24%), Positives = 66/212 (31%), Gaps = 27/212 (12%)
Query: 249 PPQSDSASSP--SPSFSEDNLPPPPA-----EFSYPVDNQRGSGLAGPKRSSVVSPSHPP 301
PP +++ P SP + P P S RG PKRS++ + +
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 163
Query: 302 PAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDF 361
+ P P P A +G+P P P P P S S H
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTE-----VGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 362 AAPPPPPPPPAADYPTLPP---------PPLSQPTGGAPP---PPPPPPPPGPPPPPFTG 409
P P+A P PLS P P P P P P P
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 410 ADGQPAIPPPLSDTTK---PKSSLPAVSDARS 438
A P + PP D P SS P + + S
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Score = 33.9 bits (76), Expect = 0.35
Identities = 37/146 (25%), Positives = 44/146 (30%), Gaps = 13/146 (8%)
Query: 287 AGPKRSSVVSPSHPPPAPPL-GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP-------- 337
AGP RS+ S +P PP G P P P P G P P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 338 ----PVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393
V G P S S D + P P P PA + AP
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196
Query: 394 PPPPPPPGPPPPPFTGADGQPAIPPP 419
P PP GP + ++ P P
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSP 222
Score = 33.1 bits (74), Expect = 0.60
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 6/82 (7%)
Query: 346 TPPPPSPPSFPPHPDFAAPPPPPPPPAA-----DYPTLPPPPLSQPTGGAPPPPPPPPPP 400
TP +P P P + PPPP PAA + PL++ GG P P
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 401 GPPPPPFTGADGQ-PAIPPPLS 421
P G + PA PP S
Sbjct: 76 RAGPTRSAGTSSRNPASRPPAS 97
Score = 30.4 bits (67), Expect = 3.9
Identities = 26/88 (29%), Positives = 31/88 (35%), Gaps = 14/88 (15%)
Query: 247 PPPPQSDSASS----PSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPP- 301
PPPP S S SS P + + P E G A P + ++ HP
Sbjct: 880 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939
Query: 302 ----PAPPLGSPPGPKPGFAPPPAPPPP 325
PAPPL P P P PP
Sbjct: 940 WSRGPAPPLAFRGAPGA-----PLPWPP 962
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 99.4 bits (246), Expect = 7e-21
Identities = 65/157 (41%), Positives = 75/157 (47%), Gaps = 23/157 (14%)
Query: 292 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTP---- 347
S++ + PP A P + P AP A P PPP +P P G+P P
Sbjct: 1400 SAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPP----LPGLPSANSNGTPEPPLLEE 1455
Query: 348 -PPPSPPSFP-PHPDFAAPPPPPPPPAADYPTLP-PPPLSQPTGGAPPPPPPPPPPGP-- 402
PPP+PP P P P PPPPPPPP P LP PPPL PT +PPPPP PPPP P
Sbjct: 1456 KPPPTPPPAPTPQPQ---PPPPPPPP---QPALPSPPPLVAPTPSSPPPPPLPPPPPPAM 1509
Query: 403 --PPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDAR 437
PPPP A A PP + P P + D R
Sbjct: 1510 PSPPPPPPPAAAPLAAPP--EEPAAPSPEDPELPDTR 1544
Score = 99.0 bits (245), Expect = 9e-21
Identities = 62/141 (43%), Positives = 66/141 (46%), Gaps = 25/141 (17%)
Query: 286 LAGPKRSSVVSPSHPPPAPPLGSP-PGPKPGFA----------------PPPAPPPPPPP 328
LAGPK +S +P PP AP P P P PG PPP PPP P P
Sbjct: 1410 LAGPKDTS--TPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
Query: 329 MIGIPPPPPPVGFGSPGTPPPPSP-PSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPT 387
PPPPPP P PP +P PS PP P P PPPPPPA P PPPP + P
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP----PLPPPPPPAMPSPPPPPPPAAAPL 1523
Query: 388 GGAPPPPPPPPPPGPPPPPFT 408
APP P P P P P T
Sbjct: 1524 -AAPPEEPAAPSPEDPELPDT 1543
Score = 84.7 bits (208), Expect = 2e-16
Identities = 50/137 (36%), Positives = 63/137 (45%), Gaps = 32/137 (23%)
Query: 247 PPP----PQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPP 302
PPP P ++S +P P E+ PP P P + PPP
Sbjct: 1433 PPPLPGLPSANSNGTPEPPLLEEKPPPTP-----------------PPAPTPQPQPPPPP 1475
Query: 303 APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFA 362
PP + P P P AP P+ PPPPP +PPPPPP + +PPPP PP+ P A
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPP----LPPPPPP----AMPSPPPPPPPAAAP---LA 1524
Query: 363 APPPPPPPPAADYPTLP 379
APP P P+ + P LP
Sbjct: 1525 APPEEPAAPSPEDPELP 1541
Score = 64.3 bits (155), Expect = 2e-10
Identities = 59/189 (31%), Positives = 64/189 (33%), Gaps = 35/189 (18%)
Query: 287 AGPKRSSVVSPSHPPPAPPLGSPPGPKP---------GFAPPPAPPPPP---PPMIGIPP 334
AG K PPP PP P P P PPPPP P ++ P
Sbjct: 751 AGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAP 810
Query: 335 PPPP----VGF---------GSPGTPPPPSPPSFPPHP--------DFAAPPPPPPPPAA 373
P P VG G+P PPPP PP PP P P P P
Sbjct: 811 SPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP-PPMPLQLEAHLRSHGLEPAAPSPRLR 869
Query: 374 DYPTLPPPPLSQPTGGA-PPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPA 432
+L PP Q GA P PP P G PP G D A P TK +P
Sbjct: 870 PEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPL 929
Query: 433 VSDARSDLL 441
S D L
Sbjct: 930 TSICFPDSL 938
Score = 63.9 bits (154), Expect = 3e-10
Identities = 90/360 (25%), Positives = 114/360 (31%), Gaps = 113/360 (31%)
Query: 180 KEKKDNPNRGNVNPRKIKTRKEEW--EKMKMGQEFVES-----KEKLGTSGYPPTLVYQN 232
KEKK P RG P + T + ++G +S T P L+ +
Sbjct: 726 KEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEA 785
Query: 233 GSIGCVENVDASSYPPPPQ-----SDSASSPSPSFSEDNL--------------PPPPAE 273
G ++ PPPPQ A SPSPS S+ + PPPP
Sbjct: 786 GG----PDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPP 841
Query: 274 FSYPVDNQRGSGLAGPKRSSVVSPSHPPP-APPLGS--PPGPKPGFAPPPAPPPPPPPMI 330
P+ Q L RS + P+ P P P S PPG P PP P
Sbjct: 842 PPPPMPLQ----LEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDT 897
Query: 331 GIPPP-------------PPPVGFGSPGTPPPPS-------------------------- 351
G+ PP P P G +P P S
Sbjct: 898 GVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGG 957
Query: 352 ---------PPSFPPHPDFAAPPPPPPPPAADY-------------------------PT 377
PP P A PPP PP Y P
Sbjct: 958 AADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPE 1017
Query: 378 LPPPPLSQPTG---GAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVS 434
LP ++P G P PPPPP PPPPP ++ + + P+ +TKPK L S
Sbjct: 1018 LPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSS 1077
Score = 58.5 bits (140), Expect = 1e-08
Identities = 60/219 (27%), Positives = 62/219 (28%), Gaps = 87/219 (39%)
Query: 299 HPPP-----APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPP---- 349
HPP PPL SPP P P P PP +P PPP FG G
Sbjct: 1295 HPPLYQAGLTPPL-SPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESE 1353
Query: 350 ------PSP---------------PSF---------------------------PP---H 358
PSP PSF PP
Sbjct: 1354 GLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGP 1413
Query: 359 PDFAAPPPPPPPPAADYPTLP--------------------------PPPLSQPTGGAPP 392
D + P PP PAA P P PPP P PP
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPP 1473
Query: 393 PPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLP 431
PPPPP P P PPP PPPL P P
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
Score = 56.2 bits (134), Expect = 7e-08
Identities = 44/131 (33%), Positives = 53/131 (40%), Gaps = 13/131 (9%)
Query: 321 APPPPPPPMIGIPPPPPPVGF--GSPGTPP--PPSPPSFPPHPDFAAPPPPPPPPAADYP 376
+PPPPPP P P + G P P PP PP P AP P P
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVH 822
Query: 377 TLPPPPLSQPTGGAPPPPPPPPPPGPP---PPPFTGADGQPAIPPPLSDTTKPKSSLPAV 433
L P ++ PPPPPPPPPP P +PA P P +P+ SL
Sbjct: 823 LLEPA--TRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP---RLRPEESLDP- 876
Query: 434 SDARSDLLSAI 444
A +LL A+
Sbjct: 877 PGAMQELLGAL 887
Score = 54.7 bits (130), Expect = 2e-07
Identities = 66/229 (28%), Positives = 74/229 (32%), Gaps = 67/229 (29%)
Query: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303
S+Y P S P PS PP FS P + GL P + PS P
Sbjct: 149 SAYQHPASFGSRPFPVPSSLSLQDPP----FSPPAN-----GLLSPHDVLHLKPSQAPTV 199
Query: 304 PP-LG----------SPPGPKPGFAPP--PAPPPPPPPMIGIPPP--------------- 335
P LG P G P PP P PP PPPP +P
Sbjct: 200 PSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAE 259
Query: 336 --PPPVGFGSPGTPPPPSPPSFPPHPDF---------AAPPPPPPPPA----------AD 374
P + S P PP P P D +A PPPPPPPA
Sbjct: 260 QSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGS 319
Query: 375 YPT------LPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIP 417
YP+ L PL GG P P P P GA G+ P
Sbjct: 320 YPSMGHRANLACSPLG---GGEPSPGAGEPSKAGPSGATAGASGRATGP 365
Score = 46.6 bits (109), Expect = 5e-05
Identities = 40/136 (29%), Positives = 47/136 (34%), Gaps = 17/136 (12%)
Query: 288 GPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPP-PPMIGIPPPPPPVGFGSPGT 346
GP SS++S P PGP F P P + P FGS
Sbjct: 103 GPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPF 162
Query: 347 PPPPS-----PPSFPPHPDFAAP---------PPPPPPPAADYPTLPPPPLSQPTGGAPP 392
P P S PP PP +P P P + + L + P G P
Sbjct: 163 PVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPA 222
Query: 393 PPPP--PPPPGPPPPP 406
PP P PP PPPPP
Sbjct: 223 QTPPYRPGPPDPPPPP 238
Score = 41.6 bits (96), Expect = 0.002
Identities = 24/75 (32%), Positives = 26/75 (34%), Gaps = 12/75 (16%)
Query: 325 PPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLS 384
PP P+ PV G PPP AP PPP P + T PP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPK------------APAPPPKPETPEKTTSEKPPEQ 1717
Query: 385 QPTGGAPPPPPPPPP 399
P P PP P P
Sbjct: 1718 TPETAMPEPPAPEKP 1732
Score = 39.3 bits (90), Expect = 0.008
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 16/80 (20%)
Query: 382 PLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLL 441
P+S APPP P PPP P P T ++ P P + P P++
Sbjct: 1683 PVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSL-------- 1734
Query: 442 SAIRQGFQLRRVEEQREQEK 461
LR VE+++E+EK
Sbjct: 1735 --------LRPVEKEKEKEK 1746
Score = 37.7 bits (86), Expect = 0.024
Identities = 54/230 (23%), Positives = 71/230 (30%), Gaps = 55/230 (23%)
Query: 220 GTSGYPPTLV---YQNGSIGCVENVDASSYPPPPQS------DSASSPSPSFSEDNLPPP 270
G GY P + Y+ G G ++ PPPP+S S P+ +++
Sbjct: 376 GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGA 435
Query: 271 PAEFSYPVDNQRGSGLAGPKR-------------SSVVSPSHPPPAPPLGSPP------- 310
+ GL GP+ S S S PP PP G PP
Sbjct: 436 GGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQ 495
Query: 311 --------GPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPP---------PPS-- 351
G G P P P G+P P + + + +P P S
Sbjct: 496 SYSPDQLQGQLYGVQGEPYPGPAAHSQ-GLPTASPSLSYSTGHSPALSGHGGGWGPSSLG 554
Query: 352 -----PPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPP 396
PS P +PP PP P P LS AP PP
Sbjct: 555 GGGEASPSHIIRP-LQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPP 603
Score = 36.6 bits (83), Expect = 0.054
Identities = 42/139 (30%), Positives = 48/139 (34%), Gaps = 14/139 (10%)
Query: 297 PSHPPPAPPLGSPPGPKPGFAP-PPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSF 355
P H PP P S P A APPP P PPP P + PP
Sbjct: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAP----APPPKPETPEKTTSEKPPEQT--- 1718
Query: 356 PPHPDFAAP-PPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTG-ADGQ 413
P+ A P PP P P+ P + T G P G P A GQ
Sbjct: 1719 ---PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQ 1775
Query: 414 PAIPP-PLSDTTKPKSSLP 431
PA P + TK K+ P
Sbjct: 1776 PATSRLPKARPTKVKAEPP 1794
Score = 30.8 bits (68), Expect = 3.0
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 282 RGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPP 338
R SG A S+ S + PP AP PP P+ PP P +P PP P
Sbjct: 1675 RRSGQAKNPVSAGGSSAPPPKAP--APPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 97.8 bits (242), Expect = 2e-20
Identities = 70/209 (33%), Positives = 84/209 (40%), Gaps = 26/209 (12%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PP + S SP+ + LP PP Q LA P + SP PP PL
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
Query: 307 GSPPGPKPG----------FAPPPAPP------PPPPPMIG---IPPPPPPVGFGSPGTP 347
+P P F+PPP+PP PP P + PP P +P
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
Query: 348 PPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP- 406
PPSPP+ PP A PPP PPP A PP L++P APP PP P PP
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLA----APPLQLAKPPPQAPPALATPPLQALPSPPA 536
Query: 407 -FTG-ADGQPAIPPPLSDTTKPKSSLPAV 433
F G A P+ P+S P P V
Sbjct: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Score = 92.4 bits (228), Expect = 8e-19
Identities = 80/237 (33%), Positives = 89/237 (37%), Gaps = 49/237 (20%)
Query: 247 PPPPQSDSAS---SPSPS-------------FSEDNLPPPPAEFSYPVDNQRGSGLAGPK 290
P PP S S +PSP FS PP A FS P + P
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--------SPPV 460
Query: 291 RSSVVSPSHPPP---APPLGSPPGP------KPGFAPPPAPPPP---PPPMIGIPPPPPP 338
S PS PP APPL PP P P PPP PPP PP + PPP P
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Query: 339 VGFGSPGTPPPPSPP-SFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPP 397
+P PSPP SFP F+ P P A P PP L+ P PP PP
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 580
Query: 398 P----PPGPPPP-PFTGADG-------QPAIPPPLSDTTKPKSSLPAVSDARSDLLS 442
P P PP P P T G P PPP S + S P ++ S S
Sbjct: 581 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 637
Score = 84.0 bits (206), Expect = 3e-16
Identities = 70/191 (36%), Positives = 79/191 (41%), Gaps = 48/191 (25%)
Query: 241 VDASSYPP--PPQSDSASSPS---PSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVV 295
V A PP PP S SA+ PS PS + L PP+ P S +
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS----------------PPASPPM 491
Query: 296 SPSHPPPA---PPLGSPPGP--KPGFAPPPAPPP-PPPPMIGIPPPPPPVGFGSPGTPPP 349
SPS PP PPL +PP KP PP APP PP+ +P PP PG P
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALATPPLQALPSPPA----SFPGQAPF 544
Query: 350 PSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP---------- 399
S P P PP PP AA +PP P + PT AP PP P P
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 604
Query: 400 ----PGPPPPP 406
PGPPPPP
Sbjct: 605 LALAPGPPPPP 615
Score = 77.0 bits (188), Expect = 4e-14
Identities = 64/204 (31%), Positives = 80/204 (39%), Gaps = 30/204 (14%)
Query: 242 DASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPP 301
DA+ P S ++PSPS + + PP + P + LA P + SPS PP
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPAT-PHSSSLTCQLATPLPLAPPSPSAPP 349
Query: 302 PAPPLGSPPGPKPGFAPPPAPPP---------PPPPM--IGIPPPPPPVGFGSPGTPPPP 350
L SPP P A P P PP+ + PPP P P PP
Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409
Query: 351 SPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGA 410
SPP+ PP A P P P A + L Q AP PPP PP P P
Sbjct: 410 SPPASPPLSPLATPSPQAPNALAVH-------LLQ----APFSPPPSPPVQAPFSP---- 454
Query: 411 DGQPAIPPPLSDTTKPKSSLPAVS 434
PA PP T P + P+++
Sbjct: 455 ---PASPPVSPSATPPSQAPPSLA 475
Score = 72.8 bits (177), Expect = 7e-13
Identities = 66/202 (32%), Positives = 78/202 (38%), Gaps = 26/202 (12%)
Query: 256 SSPSPSFSEDNLPP---PPAEFSYPVDNQRGSG-LAGPKRSSVVSPSHPP--PAPPLGSP 309
S P P + PP PP + + P S LA P S+ + PP PA P S
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
Query: 310 PGPKPGFAPPPAPPPP--PPPMIGIPPPP---PPVGFGSPGTPPPPSPPSFPPHPDF--- 361
+ P APP P PP + +P PP P S G+P + SF P P
Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 389
Query: 362 AAPPPPPPPPAADYP--TLPPPPLSQPTGGAPPPPPPPP----------PPGPPPPPFTG 409
A PPP PP A P P PP S P P P P P PPP P
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
Query: 410 ADGQPAIPPPLSDTTKPKSSLP 431
A P PP+S + P S P
Sbjct: 450 APFSPPASPPVSPSATPPSQAP 471
Score = 65.1 bits (157), Expect = 1e-10
Identities = 66/240 (27%), Positives = 79/240 (32%), Gaps = 58/240 (24%)
Query: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303
S+ P PP S S + P PA P G GL P S+ S + P +
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP---SAGGGLQRPASRSLSSSATPLSS 251
Query: 304 PPLGSPPG------------PKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
P P PKP PP PP P P+ TP P +
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 311
Query: 352 ------PPSFPPHPDFA------------APPPPPPPPAADYPTLPPPPLSQPTG----- 388
PP+ P P + APP P PP+ TLP PP + P+
Sbjct: 312 ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ--TLPSPPATPPSQATTSL 369
Query: 389 GAP---------PPPPPPPPPGPPP--------PPFTGADGQPAIPPPLSDTTKPKSSLP 431
G+P P PP P PPP PP PA PPLS P P
Sbjct: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA-SPPLSPLATPSPQAP 428
Score = 40.0 bits (92), Expect = 0.005
Identities = 52/217 (23%), Positives = 68/217 (31%), Gaps = 27/217 (12%)
Query: 249 PPQSDSASSP--SPSFSEDNLPPPPA-----EFSYPVDNQRGSGLAGPKRSSVVSPSHPP 301
PP +++ P SP + P P S RG PKRS++ + +
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 163
Query: 302 PAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDF 361
+ P P P A +G+P P P P P S S H
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTE-----VGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 362 AAPPPPPPPPAADYPTLPP---------PPLSQPTGGAPP---PPPPPPPPGPPPPPFTG 409
P P+A P PLS P P P P P P P
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 410 ADGQPAIPPPLSDTTK---PKSSLPAVSDARSDLLSA 443
A P + PP D P SS P + + S L +
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315
Score = 33.9 bits (76), Expect = 0.35
Identities = 37/146 (25%), Positives = 44/146 (30%), Gaps = 13/146 (8%)
Query: 287 AGPKRSSVVSPSHPPPAPPL-GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP-------- 337
AGP RS+ S +P PP G P P P P G P P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 338 ----PVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393
V G P S S D + P P P PA + AP
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196
Query: 394 PPPPPPPGPPPPPFTGADGQPAIPPP 419
P PP GP + ++ P P
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSP 222
Score = 33.1 bits (74), Expect = 0.60
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 6/82 (7%)
Query: 346 TPPPPSPPSFPPHPDFAAPPPPPPPPAA-----DYPTLPPPPLSQPTGGAPPPPPPPPPP 400
TP +P P P + PPPP PAA + PL++ GG P P
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 401 GPPPPPFTGADGQ-PAIPPPLS 421
P G + PA PP S
Sbjct: 76 RAGPTRSAGTSSRNPASRPPAS 97
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 97.8 bits (242), Expect = 2e-20
Identities = 70/209 (33%), Positives = 84/209 (40%), Gaps = 26/209 (12%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PP + S SP+ + LP PP Q LA P + SP PP PL
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 381
Query: 307 GSPPGPKPG----------FAPPPAPP------PPPPPMIG---IPPPPPPVGFGSPGTP 347
+P P F+PPP+PP PP P + PP P +P
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 348 PPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP- 406
PPSPP+ PP A PPP PPP A PP L++P APP PP P PP
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLA----APPLQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 407 -FTG-ADGQPAIPPPLSDTTKPKSSLPAV 433
F G A P+ P+S P P V
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPV 526
Score = 97.1 bits (240), Expect = 3e-20
Identities = 75/216 (34%), Positives = 89/216 (41%), Gaps = 38/216 (17%)
Query: 243 ASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPP 302
+SS P + SPS S LP PPA +Q + L P + S PP
Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPA----TPPSQATTSLGSPTLQATHSFLPSPP 346
Query: 303 APPLGS-PPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTP-------------P 348
PL + PP P A PP PP PP PP P+ SP P P
Sbjct: 347 LSPLATPPPQAPPALALPPLQAPPSPP---ASPPLSPLATPSPQAPNALAVHLLQAPFSP 403
Query: 349 PPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPP---------PPPP 399
PPSPP P F+ P PP P+A P+ PP L+ P PP PP PPP
Sbjct: 404 PPSPPVQAP---FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Query: 400 PGPPP---PPFTGADGQPAIPPPLSDTTKPKSSLPA 432
PPP PP A P PP L+ T P +LP+
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALA--TPPLQALPS 494
Score = 92.4 bits (228), Expect = 8e-19
Identities = 80/237 (33%), Positives = 89/237 (37%), Gaps = 49/237 (20%)
Query: 247 PPPPQSDSAS---SPSPS-------------FSEDNLPPPPAEFSYPVDNQRGSGLAGPK 290
P PP S S +PSP FS PP A FS P + P
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--------SPPV 421
Query: 291 RSSVVSPSHPPP---APPLGSPPGP------KPGFAPPPAPPPP---PPPMIGIPPPPPP 338
S PS PP APPL PP P P PPP PPP PP + PPP P
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481
Query: 339 VGFGSPGTPPPPSPP-SFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPP 397
+P PSPP SFP F+ P P A P PP L+ P PP PP
Sbjct: 482 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 541
Query: 398 P----PPGPPPP-PFTGADG-------QPAIPPPLSDTTKPKSSLPAVSDARSDLLS 442
P P PP P P T G P PPP S + S P ++ S S
Sbjct: 542 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 598
Score = 84.0 bits (206), Expect = 3e-16
Identities = 70/191 (36%), Positives = 79/191 (41%), Gaps = 48/191 (25%)
Query: 241 VDASSYPP--PPQSDSASSPS---PSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVV 295
V A PP PP S SA+ PS PS + L PP+ P S +
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS----------------PPASPPM 452
Query: 296 SPSHPPPA---PPLGSPPGP--KPGFAPPPAPPP-PPPPMIGIPPPPPPVGFGSPGTPPP 349
SPS PP PPL +PP KP PP APP PP+ +P PP PG P
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALATPPLQALPSPPA----SFPGQAPF 505
Query: 350 PSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP---------- 399
S P P PP PP AA +PP P + PT AP PP P P
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 565
Query: 400 ----PGPPPPP 406
PGPPPPP
Sbjct: 566 LALAPGPPPPP 576
Score = 75.1 bits (183), Expect = 1e-13
Identities = 63/194 (32%), Positives = 75/194 (38%), Gaps = 33/194 (17%)
Query: 256 SSPSPSFSEDNLPP---PPAEFSYPVDNQRGSG-LAGPKRSSVVSPSHPPPAPPLGSPPG 311
S P P + PP PP + + P S LA P S+ SPS PP L SPP
Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320
Query: 312 PKPGFAPPPAPPP---------PPPPM--IGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD 360
P A P P PP+ + PPP P P PPSPP+ PP
Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 380
Query: 361 FAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPL 420
A P P P A + L Q AP PPP PP P P PA PP
Sbjct: 381 LATPSPQAPNALAVH-------LLQ----APFSPPPSPPVQAPFSP-------PASPPVS 422
Query: 421 SDTTKPKSSLPAVS 434
T P + P+++
Sbjct: 423 PSATPPSQAPPSLA 436
Score = 74.3 bits (181), Expect = 2e-13
Identities = 67/207 (32%), Positives = 76/207 (36%), Gaps = 27/207 (13%)
Query: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP--P 301
SS P S + S PS P PA S P + GL + V P P
Sbjct: 234 SSSATPLSSPARSGPSAR----GTPRAPAHPSQP----KPKGLQALRPPQVTPPRKDAAP 285
Query: 302 PAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPP--PPPVGFGSPGTPPPPSPPSFPPHP 359
PL S P P + PP+P PP PP PP S G+P + SF P P
Sbjct: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345
Query: 360 DF---AAPPPPPPPPAADYP--TLPPPPLSQPTGGAPPPPPPPP----------PPGPPP 404
A PPP PP A P P PP S P P P P P PPP
Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405
Query: 405 PPFTGADGQPAIPPPLSDTTKPKSSLP 431
P A P PP+S + P S P
Sbjct: 406 SPPVQAPFSPPASPPVSPSATPPSQAP 432
Score = 73.9 bits (180), Expect = 3e-13
Identities = 62/208 (29%), Positives = 71/208 (34%), Gaps = 24/208 (11%)
Query: 244 SSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA 303
S+ P PP S S + P PA P G GL P S+ S + P +
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP---SAGGGLQRPASRSLSSSATPLSS 242
Query: 304 PPLGSPPG------------PKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
P P PKP PP PP P P+ TP P +
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302
Query: 352 PPSFPPHPDF-AAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPP---PPPGPPP--- 404
PPS P P PP PP+ +L P L P PP P PPP PP
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362
Query: 405 -PPFTGADGQPAIPPPLSDTTKPKSSLP 431
PP PA PPLS P P
Sbjct: 363 LPPLQAPPSPPA-SPPLSPLATPSPQAP 389
Score = 42.0 bits (97), Expect = 0.001
Identities = 62/269 (23%), Positives = 78/269 (28%), Gaps = 91/269 (33%)
Query: 249 PPQSDSASSP--SPSFSEDNLPPPPA-----EFSYPVDNQRGSGLAGPKRSSVVSPSHPP 301
PP +++ P SP + P P S RG PKRS++ + +
Sbjct: 95 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 154
Query: 302 PAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP-------------PVGFGSPGTPP 348
+ P P P A +G+P P P V S +
Sbjct: 155 TSGPTPGTPSPAMARRSRAAGTE-----VGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 209
Query: 349 PPSP----------------------------------------PSFPPHPDFAAP---- 364
PSP P P HP P
Sbjct: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 269
Query: 365 ---PPPPPPPAAD-YPTLPP---PPLSQPTGGAPPPPPPPP-------PPGPPPPPFTGA 410
PP PP D P L P PL+ P+ APP P PP PP PP T +
Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329
Query: 411 DGQPAI--------PPPLSDTTKPKSSLP 431
G P + PPLS P P
Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAP 358
Score = 33.9 bits (76), Expect = 0.35
Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 7/93 (7%)
Query: 346 TPPPPSPPSFPPHPDFAAPPPPPPPPAA-----DYPTLPPPPLSQPTG--GAPPPPPPPP 398
TP +P P P + PPPP PAA + PL++ G G P P
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 399 PPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLP 431
GP A G+ PP +T+ S P
Sbjct: 76 RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSP 108
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 97.1 bits (240), Expect = 3e-20
Identities = 82/282 (29%), Positives = 110/282 (39%), Gaps = 43/282 (15%)
Query: 182 KKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTL------VYQNGSI 235
K +PN G+ + T E + G ++E +K+G+S +L + +
Sbjct: 496 KTGDPNMGD---SAVPTHWEPYTTENSG--YLEITKKMGSSSMKRSLRTNFLRYWTLTYL 550
Query: 236 GCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVV 295
D + P PP DS ++P P + P P +G +G
Sbjct: 551 ALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPP-----------TGDSGAPPVPPT 599
Query: 296 SPSHPPPAPPLG---SPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPP---- 348
S PP PP G +PP P G + APP PP G PP PP G+P PP
Sbjct: 600 GDSGAPPVPPTGDSGAPPVPPTGDSG--APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDS 657
Query: 349 --PPSPPS----FPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGP 402
PP PP+ PP P PPP PP D P PP GAPP P
Sbjct: 658 GAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGD--SGAPPVTPTGDSETA 715
Query: 403 PPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAI 444
P PP TG G P +PP P +P D++ + A+
Sbjct: 716 PVPP-TGDSGAPPVPPTGDSEAAP---VPPTDDSKEAQMPAV 753
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 96.7 bits (239), Expect = 4e-20
Identities = 65/179 (36%), Positives = 76/179 (42%), Gaps = 26/179 (14%)
Query: 239 ENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSY-------PVDNQRGSGLAGPKR 291
E +D P PP P+ S+ AE + P + G
Sbjct: 584 EELDLGLGPRPPPEPGPPDPAGLLSQT------AEVALDLVGDRTPTSEKMDEGQQSSGE 637
Query: 292 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIG--IPPPPPPVGFGSPGTPPP 349
+S P AP + S PKP P A P ++ +P PPPP G P PPP
Sbjct: 638 DMEISDDEMPSAP-ITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPP---GFPPLPPP 693
Query: 350 PSPPSFPPHPDFAAPPP-----PPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPP 403
P PP PP P F PPP PPPPPA T+PPPPL P G PPP PP PP PP
Sbjct: 694 PPPP--PPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750
Score = 92.4 bits (228), Expect = 8e-19
Identities = 59/155 (38%), Positives = 71/155 (45%), Gaps = 37/155 (23%)
Query: 251 QSDSASSPSPSFSEDNLPPPP---AEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLG 307
+ +S S+D +P P A+ P+ + P ++V +PS P PL
Sbjct: 630 EGQQSSGEDMEISDDEMPSAPITSADCPKPM-------VVTPGAAAVAAPSVLAPTLPLP 682
Query: 308 SPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPP 367
PPG F P P PPPPPPP G P PPP PPPP PP P HP PPPP
Sbjct: 683 PPPG----FPPLPPPPPPPPPQPGFPMPPP--------LPPPPPPPP-PAHPAVTVPPPP 729
Query: 368 -PPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG 401
P PP +PPPP+ PP PP PPG
Sbjct: 730 LPAPPG-----VPPPPIL--------PPLPPFPPG 751
Score = 67.8 bits (164), Expect = 2e-11
Identities = 72/246 (29%), Positives = 84/246 (34%), Gaps = 59/246 (23%)
Query: 223 GYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPA-EFSY----- 276
G PP GS G + SS P S +PSPS S LP P +FS+
Sbjct: 1342 GEPPL---SGGSSG----LSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFS 1394
Query: 277 -----------PVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSP-PGPKPGF------AP 318
P+ R +GP S V+ + P PL P P P AP
Sbjct: 1395 EPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAP 1454
Query: 319 PPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP-----------P 367
P PP P P+ PPP PG P P PP P
Sbjct: 1455 TPLPPLLPAPLASCPPPMKR----KPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLP 1510
Query: 368 PPPPAADYPTLPPP---PLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTT 424
P +P+ P L G P PPPP PP PPPPP PPP+ T
Sbjct: 1511 GQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPP----------PPPVEPTK 1560
Query: 425 KPKSSL 430
P L
Sbjct: 1561 LPFKEL 1566
Score = 65.5 bits (158), Expect = 1e-10
Identities = 72/288 (25%), Positives = 109/288 (37%), Gaps = 29/288 (10%)
Query: 161 KEKMLQDTKDIMKEKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLG 220
KE + ++ + +E+ +E++++ + + + R +E + E E G
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDE-----G 1092
Query: 221 TSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDN 280
S T+ + + SS +S S SSPS S E+ + E +
Sbjct: 1093 DSDEEETVSIVTSKAEATSSSE-SSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEE 1151
Query: 281 ---QRGSGLAGPK--RSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPP 335
+ AGP+ + P AP + S + A P P + + P
Sbjct: 1152 MVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM-LDEP 1210
Query: 336 PPPVGFGSPG-TPPPPSPPSF-----------PPHPDFAAPPP--PPPPPAADYPTLPPP 381
P PVG P + PP P PP + A PP P P D P P
Sbjct: 1211 PLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEP 1270
Query: 382 PLSQPTGGAPP--PPPPPPPPGPPPPPFTGADGQPAIPP-PLSDTTKP 426
P+ P PP PP PP PP PPP P T P++PP PL++ P
Sbjct: 1271 PMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPP 1318
Score = 63.9 bits (154), Expect = 3e-10
Identities = 44/156 (28%), Positives = 57/156 (36%), Gaps = 43/156 (27%)
Query: 204 EKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFS 263
E M++ + + S P +V + +V A + P PP P P
Sbjct: 637 EDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPP-- 694
Query: 264 EDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPP 323
PPPP + +P+ PPP PP PP PP
Sbjct: 695 ----PPPPPQPGFPM---------------------PPPLPP-------------PPPPP 716
Query: 324 PPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHP 359
PP P + +PPPP P PG PPPP P PP P
Sbjct: 717 PPAHPAVTVPPPPLP---APPGVPPPPILPPLPPFP 749
Score = 63.2 bits (152), Expect = 5e-10
Identities = 66/281 (23%), Positives = 95/281 (33%), Gaps = 51/281 (18%)
Query: 174 EKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNG 233
E + + +P+ + +EE E+ +E + ++E + ++G P Q+G
Sbjct: 1117 ESSEFESSSESSPSSSEDEEEVVAREEEEEEE----EEEMVAEESMASAG--PEDFEQDG 1170
Query: 234 -------------SIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDN 280
S+G E VD + P+ PS ++ PP P P D+
Sbjct: 1171 EEAALAPGAPAVDSLGMEEEVDIETEAVAPEE------RPSMLDE--PPLPVGVEEPADS 1222
Query: 281 QRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAP-------------------PPA 321
+ G + + S PPA + + P P AP PP
Sbjct: 1223 REPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPL 1282
Query: 322 PPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLP-- 379
PPP PP PP P P PP P PPH P P
Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGG 1342
Query: 380 PPPLSQPTGG---APPPPPPPPPPGPPPPPFTGADGQPAIP 417
PPLS + G + P P P P P P + G P P
Sbjct: 1343 EPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTP 1383
Score = 56.6 bits (135), Expect = 5e-08
Identities = 49/157 (31%), Positives = 53/157 (33%), Gaps = 39/157 (24%)
Query: 300 PPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPP------ 353
P P P G P P P P PP G+ V G P S
Sbjct: 574 PTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQ 633
Query: 354 -----------SFPPHPDFAAPPPPP----------PPPAADYPTLP-PPPLSQPTGGAP 391
P P +A P P P+ PTLP PPP P P
Sbjct: 634 SSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPP--LP 691
Query: 392 PPPPPPPP-PG--------PPPPPFTGADGQPAIPPP 419
PPPPPPPP PG PPPPP A +PPP
Sbjct: 692 PPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPP 728
Score = 56.2 bits (134), Expect = 7e-08
Identities = 56/196 (28%), Positives = 65/196 (33%), Gaps = 64/196 (32%)
Query: 296 SPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIG---IPPPPPP---------VGFGS 343
S S P P G+ +PGF P PP P G I P P P +G G
Sbjct: 536 SSSQLSPLAPFGT--NSQPGFR-GPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLG- 591
Query: 344 PGTPPPPSPP-------------------------------------------SFPPHPD 360
P PP P PP P P
Sbjct: 592 PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPI 651
Query: 361 FAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPP--PPPPPPGPPPPPFTGADGQPAIPP 418
+A P P + P + PT PPPP PP PPP PPPPP G P +PP
Sbjct: 652 TSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPP 711
Query: 419 PLSDTTKPKSSLPAVS 434
P P + PAV+
Sbjct: 712 P---PPPPPPAHPAVT 724
Score = 53.9 bits (128), Expect = 3e-07
Identities = 59/214 (27%), Positives = 71/214 (33%), Gaps = 47/214 (21%)
Query: 245 SYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAP 304
S PP P++ AS PS +PP P +P G +S+ P+ P P
Sbjct: 1292 SPPPEPETTDASHPS-------VPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEP 1344
Query: 305 PL---------------GSP---PGPKPGFAPPPAPPPP------------PPPMIGIPP 334
PL GSP P P P + P P P + +P
Sbjct: 1345 PLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPV 1404
Query: 335 PPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA--------ADYPTLPPPPLSQP 386
P P G + P SP P P P P A A PT PP L P
Sbjct: 1405 CPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAP 1464
Query: 387 TGGAPPP-PPPPPPPGPPPPPFTGADGQPAIPPP 419
PPP P P PP DG P + PP
Sbjct: 1465 LASCPPPMKRKPGRPRRSPPSMLSLDG-PLVRPP 1497
Score = 50.1 bits (118), Expect = 5e-06
Identities = 40/126 (31%), Positives = 48/126 (38%), Gaps = 27/126 (21%)
Query: 298 SHPPPAPPLGSPPGPKPGFAP---PPAPPPPPPPMIGIPPPPPPVGFGSPGT-------P 347
+H PP PG K F+P P A PPPP P FG+ +
Sbjct: 379 AHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPE-----EPTATAAFGARDSGEFRRAPA 433
Query: 348 PPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPP--------P 399
PPP PP+ P + PP PPPP + L +PT G P P P P
Sbjct: 434 PPPLPPAEPLAKEKPGTPPGPPPPDTNSMELG----GRPTFGWSPEPCDSPGTPTLESSP 489
Query: 400 PGPPPP 405
GP P
Sbjct: 490 AGPEKP 495
Score = 46.6 bits (109), Expect = 5e-05
Identities = 40/123 (32%), Positives = 48/123 (39%), Gaps = 19/123 (15%)
Query: 247 PPPPQSDSASSPSPSFSEDNLP--PPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH-PPPA 303
PPP Q+ +P+P F P P A F P + + G + S + PPP
Sbjct: 382 PPPAQA----TPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPL 437
Query: 304 PPLGSPPGPKPGFAPPPAPPPPP-------PPMIGIPPPPPPVGFGSPGTPPPPSPPSFP 356
PP KPG PP PPP P G P P SPGTP S P+ P
Sbjct: 438 PPAEPLAKEKPG-TPPGPPPPDTNSMELGGRPTFGWSPEP----CDSPGTPTLESSPAGP 492
Query: 357 PHP 359
P
Sbjct: 493 EKP 495
Score = 43.1 bits (100), Expect = 6e-04
Identities = 44/155 (28%), Positives = 53/155 (34%), Gaps = 22/155 (14%)
Query: 305 PLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAA- 363
P G+ G PP P PPP + TP P +F P+ A
Sbjct: 353 PFGAVGGTGGSSGPPFKAQPQDSATFAHTPPP------AQATPAPGFKSAFSPYQTPVAH 406
Query: 364 -PPPPPPPPAA---------DYPTLP-PPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADG 412
PPPP P A ++ P PPPL A P PP P PP G
Sbjct: 407 FPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGG 466
Query: 413 QPAI---PPPL-SDTTKPKSSLPAVSDARSDLLSA 443
+P P P S T S PA + D L +
Sbjct: 467 RPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDS 501
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 96.3 bits (238), Expect = 6e-20
Identities = 87/319 (27%), Positives = 111/319 (34%), Gaps = 125/319 (39%)
Query: 204 EKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFS 263
+K +M +E++ +LG + P ++ +G P + AS+P P+
Sbjct: 305 DKARMDKEYLSLMAELGEAPVPASVGSTSG---------------PATTPLASAPRPAAP 349
Query: 264 EDNLPPP----------------PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA---- 303
+N PPP P+E S P G G GP P HP P+
Sbjct: 350 ANNPPPPSLMSTTQSRPPWMNSGPSE-SRPYHGMHGGGPGGPGGGPHSFP-HPLPSLTGG 407
Query: 304 ----PPLGSPPGPKPGFAPPPAPP-------------PP--------------------- 325
P +P GP P + PP PP PP
Sbjct: 408 HGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGK 467
Query: 326 ---PPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP 382
PPP +G+ PPPPP G P PPPPS P PP PPPPPPP++ + P P
Sbjct: 468 GMMPPPPMGMMPPPPPPPSGQP--PPPPSGP-LPPWQQQQQQPPPPPPPSSSMASSTPLP 524
Query: 383 LSQ------------------------------------------PTGGAPPPPPPPPPP 400
Q P G PP PP PPP
Sbjct: 525 WQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPP 584
Query: 401 GPPPPPFTGADGQPAIPPP 419
PPPPP G+ G PPP
Sbjct: 585 PPPPPP--GSAGMMYAPPP 601
Score = 93.2 bits (230), Expect = 5e-19
Identities = 69/217 (31%), Positives = 81/217 (37%), Gaps = 65/217 (29%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEF--SYPVDN-----QRGSGLAGPKRSSVVSPSH 299
PPPP + P + PPP ++ S PV + +G G+ P ++ P
Sbjct: 428 PPPPMNQGPHPPG-----HHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP-- 480
Query: 300 PPPAPPLGSPPGPKPGFAPP-----PAPPPPPPPMIGIPPPPP----------PVGFGSP 344
PP PP G PP P G PP PPPPPPP + P G+
Sbjct: 481 -PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTG 539
Query: 345 GTPP----------PPSPPSFPPHPDFAAPPP---PPPPPAADYPTLPPPPLSQPTGGAP 391
PP P P +P PP PP PP A P PPPP S AP
Sbjct: 540 SIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAP 599
Query: 392 PPPPPPP----------------------PPGPPPPP 406
PPPPPPP PP PPPPP
Sbjct: 600 PPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 96.3 bits (238), Expect = 6e-20
Identities = 78/214 (36%), Positives = 81/214 (37%), Gaps = 60/214 (28%)
Query: 245 SYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAP 304
S PPP+ P P + PPP R GP PPP P
Sbjct: 110 SQGPPPRPGKPEGPPPQGGNQSQGPPP----------RPGKPEGPPPQGGNQSQGPPPRP 159
Query: 305 --PLGSPP-------GPKPGFAPPPAPPPP-------PPPMIGIPPPPPPVGFG-SPGTP 347
P G PP GP P P PPP PPP G P PPP G S G P
Sbjct: 160 GKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 219
Query: 348 P----PPSPPSF--------PPHPDFAAPPPP--------PPPPAADYPTLPPPPLSQPT 387
P P PPS PPHP PPP PPPP P PPPP
Sbjct: 220 PRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGR--PQGPPPP----- 272
Query: 388 GGAPPPPPPPP---PPGPPPPPFTGADGQPAIPP 418
GG P P PPP P GPPPPP G+P PP
Sbjct: 273 GGNPQQPLPPPAGKPQGPPPPP---QGGRPHRPP 303
Score = 92.0 bits (227), Expect = 1e-18
Identities = 79/238 (33%), Positives = 88/238 (36%), Gaps = 52/238 (21%)
Query: 245 SYPPPPQSDSASSPSPSFSEDNLPPPPA----EFSYPVDNQRGSGLA-------GPKRSS 293
S PPP+ P P + PPP E P + G GP
Sbjct: 68 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQG 127
Query: 294 VVSPSHPPPAPPLGSPPGPKP-----GFAPPPAP-----PPP--------PPPMIGIPPP 335
PPP P G P GP P PPP P PPP PPP G P
Sbjct: 128 GNQSQGPPPRP--GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEG 185
Query: 336 PPPVGFG-SPGTPPPPSPPSFPP----HPDFAAPPPP-----PPPPAADYPTLPPPPLSQ 385
PPP G S G PP P P PP + PP P PP + P PPP +
Sbjct: 186 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGK 245
Query: 386 PTGGAPPP-----PPPPPPPG-PPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDAR 437
P G PPP P PPPPG P PP G + Q +PPP KP+ P R
Sbjct: 246 PQG--PPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAG---KPQGPPPPPQGGR 298
Score = 92.0 bits (227), Expect = 1e-18
Identities = 68/193 (35%), Positives = 72/193 (37%), Gaps = 33/193 (17%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPP + + P P + PPP R GP PPP P
Sbjct: 123 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHP-- 180
Query: 307 GSPPGPKP-----GFAPPPAP-----PPP--------PPPMIGIPPPPPPVGFGSPGTPP 348
G P GP P PPP P PPP PPP G P PP G P PP
Sbjct: 181 GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPP 240
Query: 349 P-PSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP------PPPPPPPG 401
P P P PP + P PPPP P PPPP P PPP PPPPP G
Sbjct: 241 PHPGKPQGPPPQEGNKPQRPPPPGR---PQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGG 297
Query: 402 PPPPPFTGADGQP 414
P P GQP
Sbjct: 298 RPHRP---PQGQP 307
Score = 87.0 bits (214), Expect = 4e-17
Identities = 56/154 (36%), Positives = 59/154 (38%), Gaps = 10/154 (6%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
PPP + + P P + PPP R GP PPP P
Sbjct: 165 PPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP-- 222
Query: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP 366
G P GP P PPP P G P PPP P PPPP P PP P P
Sbjct: 223 GKPEGPPSQGGNKPQGPPPHP---GKPQGPPPQEGNKPQRPPPPGRPQGPPPP--GGNPQ 277
Query: 367 PPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPP 400
P PP A P PPPP P GG P PP PP
Sbjct: 278 QPLPPPAGKPQGPPPP---PQGGRPHRPPQGQPP 308
Score = 86.7 bits (213), Expect = 5e-17
Identities = 71/219 (32%), Positives = 77/219 (35%), Gaps = 41/219 (18%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPP----- 301
PPPP P PP P + P Q G+ GP PP
Sbjct: 51 PPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPP-QGGNQSQGPPPRPGKPEGQPPQGGNQ 109
Query: 302 ---PAPPLGSPPGPKP-----GFAPPPAP--PPPPPPMIGIPPPPPPVGFGSPGTPPPP- 350
P P G P GP P PPP P P PPP G PP G P PPP
Sbjct: 110 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 169
Query: 351 --SPPSFPPHPDFAAPPPPP-------PPPAADYPTLPPPPLSQPTGGAPPPPPPP---- 397
PPHP PPP PPP P PPP + G PP P P
Sbjct: 170 GNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 229
Query: 398 -----PPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLP 431
P GPPP P G+P PPP + KP+ P
Sbjct: 230 SQGGNKPQGPPPHP-----GKPQGPPP-QEGNKPQRPPP 262
Score = 72.0 bits (175), Expect = 1e-12
Identities = 60/176 (34%), Positives = 70/176 (39%), Gaps = 31/176 (17%)
Query: 255 ASSPSPSFSED-NLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPP-GP 312
A S + S +ED + P+ S + +R G P+R+ PPP P G PP G
Sbjct: 12 ALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTP------PPPGKPEGRPPQGG 65
Query: 313 KPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA 372
PPP P P P PP G S G PP P P P PPP P
Sbjct: 66 NQSQGPPPRPGKPEGP-------PPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPG 118
Query: 373 ADYPTLPPPPLSQPTGGAPP---PPPPPPP------PGPPPPPFTGADGQPAIPPP 419
P PPP + G PP P PPP GPPP P G+P PPP
Sbjct: 119 K--PEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP-----GKPEGPPP 167
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 95.9 bits (237), Expect = 8e-20
Identities = 71/243 (29%), Positives = 92/243 (37%), Gaps = 53/243 (21%)
Query: 237 CVENVDASSYPPPP----QSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSG----LAG 288
C ++ S PPPP Q + +P PPPP P+ Q +
Sbjct: 733 CAPSLPQFSAPPPPLKIHQVQHITQVAPP-----TPPPPPPIPAPLPPQAPPKPLVTIPA 787
Query: 289 PKRSSVVSPSHPPPAPPLGSPPGP----KPGFAPPPAPPPPPPPMIGIPPP--------- 335
P + V+P APP +PP P +P F PP PP P + +PPP
Sbjct: 788 PTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFC 847
Query: 336 --PPPVGFGSPGT---------PPPPSPPSFPPHPDFAAPP---PPPPPPAADYPTLPPP 381
PPP + PPPP+PP+ P P P PP P P
Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPS 907
Query: 382 PLSQPTGGAPPPPP------PPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSD 435
+ P+ PPPPP PPPPP P P P P PPP + T KS P
Sbjct: 908 SIPVPSPDFPPPPPESSLVFPPPPPSPVPAP-------PPPPPPTASPTPDKSGSPGKKT 960
Query: 436 ARS 438
+++
Sbjct: 961 SKT 963
Score = 90.1 bits (222), Expect = 4e-18
Identities = 83/272 (30%), Positives = 97/272 (35%), Gaps = 56/272 (20%)
Query: 198 TRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASS 257
T+ EE K +M ES + TS PP + + PPPP
Sbjct: 585 TQLEESSKARM-----ESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPP 639
Query: 258 PSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGP---KRSSVVSPSHP---------PPAPP 305
P P PPPP P + +G A P K S++ + PP PP
Sbjct: 640 PPP-------PPPPPPL--PSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPP 690
Query: 306 LGSPPGPKP-------GFAPPPAPPPPPPP----MIGIPPPPPPVGFGSPGTPPPPSPPS 354
+ KP G PPP PPPPPP M + P P PPPP
Sbjct: 691 VMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIH 750
Query: 355 FPPHPDFAAPPPPPPP---PAADYPTLPPPPL---SQPTG----------GAPPPPPPPP 398
H APP PPPP PA P PP PL PT APP P PP
Sbjct: 751 QVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV 810
Query: 399 PPGPPPPPFTGA---DGQPAIPPPLSDTTKPK 427
PP P F + P P P+ T PK
Sbjct: 811 PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPK 842
Score = 81.6 bits (200), Expect = 1e-15
Identities = 71/231 (30%), Positives = 90/231 (38%), Gaps = 50/231 (21%)
Query: 234 SIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDN------QRGSGLA 287
S +++ +SS P QS+ S+ S S D P V + +RG+ L
Sbjct: 530 SSSSIKSGSSSSSIPESQSNH-SNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLE 588
Query: 288 GPKRSSVVSPSHP-----PPAPPLGSPPGPKPGFAP-PPAPPPPPPPMIGIPPPPPPVGF 341
++ + S + P PP P P P PP PPPPPPP PPPPPP
Sbjct: 589 ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP----PPPPPP--- 641
Query: 342 GSPGTPPPPSPPSFPPHPDFAAPP---------------------PPPPPPAADYPTLPP 380
P PPPP P P AAP PP PP ++ P
Sbjct: 642 --PPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP 699
Query: 381 PPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLP 431
L P G PPPPP PPPPP G+ P P + + P+ S P
Sbjct: 700 QILVPPNGVVPPPPP------PPPPPTPGSAMAQLKPAPCAPSL-PQFSAP 743
Score = 75.1 bits (183), Expect = 1e-13
Identities = 67/230 (29%), Positives = 86/230 (37%), Gaps = 52/230 (22%)
Query: 243 ASSYPPPPQSDSASSPSPSFSEDN---LPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH 299
AS PP P + P P+ + PPP+ S PV + + S
Sbjct: 821 ASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS-PVPSVV---------KQIASQFP 870
Query: 300 PPPAPPL---------------GSPPGPK------PGFAPPPAP--PPPPPPMIGIPPPP 336
PPP PP SPP K P P P+P PPPPP + PPP
Sbjct: 871 PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930
Query: 337 PPVGFGSP-GTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQ------PTGG 389
PP SP PPPP PP+ P PD + P + PPP Q + G
Sbjct: 931 PP----SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG 986
Query: 390 APPPPPPPPPPGP-----PPPPFTGADGQPAIPPPLSDTTKPKSSLPAVS 434
A P P P PP +G+ + +PPP + K +L V+
Sbjct: 987 AEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVN 1036
Score = 65.1 bits (157), Expect = 1e-10
Identities = 55/185 (29%), Positives = 65/185 (35%), Gaps = 6/185 (3%)
Query: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPS--HPPPAP 304
PPPP+S P P PPPP + P ++ GS G K S SP PPP P
Sbjct: 918 PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS--PGKKTSKTSSPGGKKPPPTP 975
Query: 305 PLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAP 364
S G P P ++ PP G S T PPP+ P P + +
Sbjct: 976 QRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGV 1035
Query: 365 PPPPPPPAADYPTLPPPPLSQPTGGAPP-PPPPPPPPGPPPPPFTGADGQP-AIPPPLSD 422
P P + P PP PPPPP T P IP S
Sbjct: 1036 NLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSG 1095
Query: 423 TTKPK 427
T PK
Sbjct: 1096 NTSPK 1100
Score = 56.2 bits (134), Expect = 7e-08
Identities = 61/212 (28%), Positives = 80/212 (37%), Gaps = 45/212 (21%)
Query: 241 VDASSYPPPPQS----DSASSPSPSFSEDNLP-----PPPAEFSYPVDNQRGSGLAGPKR 291
V A PPPP + D + SP S+ + P PP + + + + G+ PKR
Sbjct: 935 VPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR 994
Query: 292 SSVVS--PSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPM----IGIP----------PP 335
SV S PPA P PPPA PP P + + +P
Sbjct: 995 PSVDSLVSKFTPPA----ESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKA 1050
Query: 336 PPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPP 395
P G G PSPPS DF PPPPP + LP PP+ P + P
Sbjct: 1051 PVLSGRGKDSVVEFPSPPS---DSDF-----PPPPPETE---LPLPPIEIPAVFSGNTSP 1099
Query: 396 PPPPPGPPPPPFTGADGQPAIPPPLSDTTKPK 427
P P ++ + A PP T+PK
Sbjct: 1100 KVAVVNPQPQQWSKMSVKKAPPP-----TRPK 1126
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/66 (39%), Positives = 28/66 (42%), Gaps = 11/66 (16%)
Query: 375 YPTLPPPPLSQPTGGAP----PPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSL 430
Y +L PP QP P P PP PPP PPPPP P PPP P S
Sbjct: 602 YTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP-------PPPPPPPPPPPLPSQSA 654
Query: 431 PAVSDA 436
P+ A
Sbjct: 655 PSAGSA 660
Score = 32.0 bits (71), Expect = 1.3
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 254 SASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSH-PPPAPP 305
S + P+ + + LPPPP E + +Q+ +G G S + PPPAPP
Sbjct: 1189 SRAEPTATMDDMALPPPPPEL---LSDQQKAGYGGSHISGYATLRRGPPPAPP 1238
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,741,313
Number of Sequences: 37866
Number of extensions: 3568419
Number of successful extensions: 171941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2105
Number of HSP's successfully gapped in prelim test: 1749
Number of HSP's that attempted gapping in prelim test: 22597
Number of HSP's gapped (non-prelim): 40815
length of query: 498
length of database: 18,247,518
effective HSP length: 106
effective length of query: 392
effective length of database: 14,233,722
effective search space: 5579619024
effective search space used: 5579619024
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.