BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor [Homo sapiens] (913 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 1862 0.0 gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 787 0.0 gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 784 0.0 gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 211 2e-54 gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 211 2e-54 gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 211 2e-54 gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 211 3e-54 gi|26190608 synaptojanin 2 [Homo sapiens] 206 6e-53 gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 186 1e-46 gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 179 1e-44 gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 165 2e-40 gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 165 2e-40 gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 161 3e-39 gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 152 1e-36 gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 152 1e-36 gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 127 5e-29 gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 74 6e-13 gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 74 6e-13 gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 74 6e-13 gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 69 2e-11 gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap... 63 1e-09 gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi... 63 1e-09 gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 59 2e-08 gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 59 2e-08 gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 59 2e-08 gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a... 57 6e-08 gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b... 57 6e-08 gi|56119110 family with sequence similarity 13, member A1 isofor... 56 2e-07 gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 54 7e-07 gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 54 7e-07 >gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor [Homo sapiens] Length = 913 Score = 1862 bits (4823), Expect = 0.0 Identities = 913/913 (100%), Positives = 913/913 (100%) Query: 1 MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRM 60 MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRM Sbjct: 1 MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRM 60 Query: 61 AITGDDVSLDQIVPVSRDFTLEEVSPDGELYILGSDVTVQLDTAELSLVFQLPFGSQTRM 120 AITGDDVSLDQIVPVSRDFTLEEVSPDGELYILGSDVTVQLDTAELSLVFQLPFGSQTRM Sbjct: 61 AITGDDVSLDQIVPVSRDFTLEEVSPDGELYILGSDVTVQLDTAELSLVFQLPFGSQTRM 120 Query: 121 FLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGGS 180 FLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGGS Sbjct: 121 FLHEVARACPGFDSATRDPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGGS 180 Query: 181 NFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQK 240 NFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQK Sbjct: 181 NFDGLRPNGKGVPMDQSSRGQDKPESLQPRQNKSKSEITDMVRSSTITVSDKAHILSMQK 240 Query: 241 FGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVG 300 FGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVG Sbjct: 241 FGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVG 300 Query: 301 FQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAY 360 FQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAY Sbjct: 301 FQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAY 360 Query: 361 ISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICS 420 ISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICS Sbjct: 361 ISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICS 420 Query: 421 RMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKI 480 RMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKI Sbjct: 421 RMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKI 480 Query: 481 QVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQS 540 QVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQS Sbjct: 481 QVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQS 540 Query: 541 HMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQ 600 HMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQ Sbjct: 541 HMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQ 600 Query: 601 NVKYMQLKVESFTIHNGQVPCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLEL 660 NVKYMQLKVESFTIHNGQVPCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLEL Sbjct: 601 NVKYMQLKVESFTIHNGQVPCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLEL 660 Query: 661 FVNKMTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILD 720 FVNKMTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILD Sbjct: 661 FVNKMTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILD 720 Query: 721 LPLETISELTLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEF 780 LPLETISELTLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEF Sbjct: 721 LPLETISELTLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEF 780 Query: 781 EHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVI 840 EHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVI Sbjct: 781 EHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVI 840 Query: 841 STLPIFHKNVFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAGHQKLDMTEKKK 900 STLPIFHKNVFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAGHQKLDMTEKKK Sbjct: 841 STLPIFHKNVFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAGHQKLDMTEKKK 900 Query: 901 AQEFIHQFLCNPL 913 AQEFIHQFLCNPL Sbjct: 901 AQEFIHQFLCNPL 913 >gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase isoform b [Homo sapiens] Length = 893 Score = 787 bits (2033), Expect = 0.0 Identities = 387/748 (51%), Positives = 528/748 (70%), Gaps = 32/748 (4%) Query: 184 GLRPNGKGVPMDQSSRGQDKPESLQ--------------PRQ----NKSKSEITDMVRSS 225 G N + +D+ Q++P + PR+ NK + ++T+ +R Sbjct: 150 GFEDNFSSMNLDKKINSQNQPTGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMR-- 207 Query: 226 TITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRL 285 K + + Q G R+ ++K L ++E++Y IQ FRFF GT+NVNGQSP L Sbjct: 208 ------KLFVPNTQS-GQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEP 260 Query: 286 WLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLV 345 WL+ PD+YC+GFQELDLS EAFF+ ++ KE+EW AV GLH AKY KV+L+RLV Sbjct: 261 WLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLV 320 Query: 346 GIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHI 405 G+MLL++ +++ YI ++ ETVGTGIMG+MGNKGGVA+RF FHNT+ C+VNSHLAAH+ Sbjct: 321 GMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHV 380 Query: 406 EEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIE 465 E++ERRNQDYKDIC+RM F P+ +LP L I H+V++WLGDLNYR+ D +VK LI Sbjct: 381 EDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLIN 440 Query: 466 EKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDR 525 +KD Q L +DQL IQ K F F EGE+ F PTYKYD+ +D WD+S KCR PAWCDR Sbjct: 441 KKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDR 500 Query: 526 ILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMENA 585 ILW+G N+ QL+Y+SHM LKTSDHKPVS++F IGV+VV++ YRK E+ VR +D+MEN Sbjct: 501 ILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDSVRIMDRMEND 560 Query: 586 NIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQVPCHFEFINKPDEESYCKQWLNANPS 644 +PS+ LS+REF F+NVK+ QL+ E F I +NGQVPCHF FI K ++ YCK WL A P Sbjct: 561 FLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPF 620 Query: 645 RGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCF 704 G+L P+ V+I L+++V+K + T LNSGEDKIEDILVLHLDRGKDYFL++SGNYLPSCF Sbjct: 621 EGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCF 680 Query: 705 GSPIHTLCYMREPILDLPLETISEL--TLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYR 762 G+ + LC M+ PI ++P+ + +L +L+ + D+G+ + P+++PKE+W++VD+L++ Sbjct: 681 GTSLEALCRMKRPIREVPVTKLIDLEKSLLQMVPLDEGAS-ERPLQVPKEIWLLVDHLFK 739 Query: 763 NAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYST 822 A QEDLFQ PG++ E + I DCLDT + + + SNHSVAEALL+FLE+LPEPVICY Sbjct: 740 YACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYEL 799 Query: 823 YHNCLECSGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNSAKNHLDENILASIFGSL 882 Y CL+ + + +QVIS LP H+NVF YLMAFLRELLK S N ++ N++A++F SL Sbjct: 800 YQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSL 859 Query: 883 LLRNPAG-HQKLDMTEKKKAQEFIHQFL 909 LLR P + +++++A +F+ FL Sbjct: 860 LLRPPPNLMARQTPSDRQRAIQFLLGFL 887 >gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase isoform a [Homo sapiens] Length = 901 Score = 784 bits (2025), Expect = 0.0 Identities = 387/756 (51%), Positives = 528/756 (69%), Gaps = 40/756 (5%) Query: 184 GLRPNGKGVPMDQSSRGQDKPESLQ--------------PRQ----NKSKSEITDMVRSS 225 G N + +D+ Q++P + PR+ NK + ++T+ +R Sbjct: 150 GFEDNFSSMNLDKKINSQNQPTGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMR-- 207 Query: 226 TITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRL 285 K + + Q G R+ ++K L ++E++Y IQ FRFF GT+NVNGQSP L Sbjct: 208 ------KLFVPNTQS-GQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEP 260 Query: 286 WLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLV 345 WL+ PD+YC+GFQELDLS EAFF+ ++ KE+EW AV GLH AKY KV+L+RLV Sbjct: 261 WLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLV 320 Query: 346 GIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHI 405 G+MLL++ +++ YI ++ ETVGTGIMG+MGNKGGVA+RF FHNT+ C+VNSHLAAH+ Sbjct: 321 GMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHV 380 Query: 406 EEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIE 465 E++ERRNQDYKDIC+RM F P+ +LP L I H+V++WLGDLNYR+ D +VK LI Sbjct: 381 EDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLIN 440 Query: 466 EKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDR 525 +KD Q L +DQL IQ K F F EGE+ F PTYKYD+ +D WD+S KCR PAWCDR Sbjct: 441 KKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDR 500 Query: 526 ILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMENA 585 ILW+G N+ QL+Y+SHM LKTSDHKPVS++F IGV+VV++ YRK E+ VR +D+MEN Sbjct: 501 ILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDSVRIMDRMEND 560 Query: 586 NIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQVPCHFEFINKPDEESYCKQWLNANPS 644 +PS+ LS+REF F+NVK+ QL+ E F I +NGQVPCHF FI K ++ YCK WL A P Sbjct: 561 FLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPF 620 Query: 645 RGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCF 704 G+L P+ V+I L+++V+K + T LNSGEDKIEDILVLHLDRGKDYFL++SGNYLPSCF Sbjct: 621 EGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCF 680 Query: 705 GSPIHTLCYMREPILDLPLETISEL----------TLMPVWTGDDGSQLDSPMEIPKELW 754 G+ + LC M+ PI ++P+ + +L +L+ + D+G+ + P+++PKE+W Sbjct: 681 GTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGAS-ERPLQVPKEIW 739 Query: 755 MMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNHSVAEALLLFLESLP 814 ++VD+L++ A QEDLFQ PG++ E + I DCLDT + + + SNHSVAEALL+FLE+LP Sbjct: 740 LLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALP 799 Query: 815 EPVICYSTYHNCLECSGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNSAKNHLDENI 874 EPVICY Y CL+ + + +QVIS LP H+NVF YLMAFLRELLK S N ++ N+ Sbjct: 800 EPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANM 859 Query: 875 LASIFGSLLLRNPAG-HQKLDMTEKKKAQEFIHQFL 909 +A++F SLLLR P + +++++A +F+ FL Sbjct: 860 IATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFL 895 >gi|237757312 synaptojanin 1 isoform c [Homo sapiens] Length = 1295 Score = 211 bits (538), Expect = 2e-54 Identities = 138/416 (33%), Positives = 214/416 (51%), Gaps = 63/416 (15%) Query: 212 NKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGT 271 N S++ D R+ T S + ++Q + ++KS + + Y+ + R GT Sbjct: 483 NTLNSDLADKARALLTTGSLRVSEQTLQSASSK--VLKS-MCENFYKYSKPKKIRVCVGT 539 Query: 272 YNVNGQSP-------KECLRLWLSN-----GIQA--------PDVYCVGFQEL-DLSKEA 310 +NVNG + L WL + GIQ D++ +GF+E+ +L+ Sbjct: 540 WNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGN 599 Query: 311 FFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG 370 T ++ W + + + D KY + +LVG+ L ++++ +HA +I +V +TV Sbjct: 600 IVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVK 659 Query: 371 TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPS 430 TG+ G GNKG VAIR FH TS+C V SH AA + + RN+D+ +I ++ F Sbjct: 660 TGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSF------ 713 Query: 431 LPPL--TISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVF 488 P+ + +HD + W GD NYRI+ L E+VK+LI ++++ L A DQL Q A VF Sbjct: 714 --PMGRMLFSHDYVFWCGDFNYRID-LPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVF 770 Query: 489 EGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK-----------NITQLS 537 GF EG++TF PTYKYD SDD+DTSEKCR PAW DR+LW+ + ++ S Sbjct: 771 RGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNAS 830 Query: 538 YQ-----------------SHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIV 576 +Q LKTSDH+PV ++ DI + V E + +E++ Sbjct: 831 FQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVI 886 >gi|237757310 synaptojanin 1 isoform a [Homo sapiens] Length = 1612 Score = 211 bits (538), Expect = 2e-54 Identities = 138/416 (33%), Positives = 214/416 (51%), Gaps = 63/416 (15%) Query: 212 NKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGT 271 N S++ D R+ T S + ++Q + ++KS + + Y+ + R GT Sbjct: 522 NTLNSDLADKARALLTTGSLRVSEQTLQSASSK--VLKS-MCENFYKYSKPKKIRVCVGT 578 Query: 272 YNVNGQSP-------KECLRLWLSN-----GIQA--------PDVYCVGFQEL-DLSKEA 310 +NVNG + L WL + GIQ D++ +GF+E+ +L+ Sbjct: 579 WNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGN 638 Query: 311 FFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG 370 T ++ W + + + D KY + +LVG+ L ++++ +HA +I +V +TV Sbjct: 639 IVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVK 698 Query: 371 TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPS 430 TG+ G GNKG VAIR FH TS+C V SH AA + + RN+D+ +I ++ F Sbjct: 699 TGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSF------ 752 Query: 431 LPPL--TISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVF 488 P+ + +HD + W GD NYRI+ L E+VK+LI ++++ L A DQL Q A VF Sbjct: 753 --PMGRMLFSHDYVFWCGDFNYRID-LPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVF 809 Query: 489 EGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK-----------NITQLS 537 GF EG++TF PTYKYD SDD+DTSEKCR PAW DR+LW+ + ++ S Sbjct: 810 RGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNAS 869 Query: 538 YQ-----------------SHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIV 576 +Q LKTSDH+PV ++ DI + V E + +E++ Sbjct: 870 FQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVI 925 >gi|237757308 synaptojanin 1 isoform b [Homo sapiens] Length = 1350 Score = 211 bits (538), Expect = 2e-54 Identities = 138/416 (33%), Positives = 214/416 (51%), Gaps = 63/416 (15%) Query: 212 NKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGT 271 N S++ D R+ T S + ++Q + ++KS + + Y+ + R GT Sbjct: 522 NTLNSDLADKARALLTTGSLRVSEQTLQSASSK--VLKS-MCENFYKYSKPKKIRVCVGT 578 Query: 272 YNVNGQSP-------KECLRLWLSN-----GIQA--------PDVYCVGFQEL-DLSKEA 310 +NVNG + L WL + GIQ D++ +GF+E+ +L+ Sbjct: 579 WNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGN 638 Query: 311 FFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG 370 T ++ W + + + D KY + +LVG+ L ++++ +HA +I +V +TV Sbjct: 639 IVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVK 698 Query: 371 TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPS 430 TG+ G GNKG VAIR FH TS+C V SH AA + + RN+D+ +I ++ F Sbjct: 699 TGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSF------ 752 Query: 431 LPPL--TISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVF 488 P+ + +HD + W GD NYRI+ L E+VK+LI ++++ L A DQL Q A VF Sbjct: 753 --PMGRMLFSHDYVFWCGDFNYRID-LPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVF 809 Query: 489 EGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK-----------NITQLS 537 GF EG++TF PTYKYD SDD+DTSEKCR PAW DR+LW+ + ++ S Sbjct: 810 RGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNAS 869 Query: 538 YQ-----------------SHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIV 576 +Q LKTSDH+PV ++ DI + V E + +E++ Sbjct: 870 FQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVI 925 >gi|237757326 synaptojanin 1 isoform d [Homo sapiens] Length = 1526 Score = 211 bits (536), Expect = 3e-54 Identities = 139/420 (33%), Positives = 213/420 (50%), Gaps = 65/420 (15%) Query: 212 NKSKSEITDMVRSSTITVSDKAH----ILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRF 267 + SK E D++ SD A +L+ ++KS + + Y+ + R Sbjct: 472 DSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRASSKVLKS-MCENFYKYSKPKKIRV 530 Query: 268 FAGTYNVNGQSP-------KECLRLWLSN-----GIQA--------PDVYCVGFQEL-DL 306 GT+NVNG + L WL + GIQ D++ +GF+E+ +L Sbjct: 531 CVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVEL 590 Query: 307 SKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEA 366 + T ++ W + + + D KY + +LVG+ L ++++ +HA +I +V Sbjct: 591 NAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAV 650 Query: 367 ETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQ 426 +TV TG+ G GNKG VAIR FH TS+C V SH AA + + RN+D+ +I ++ F Sbjct: 651 DTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSF-- 708 Query: 427 PDPSLPPL--TISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAA 484 P+ + +HD + W GD NYRI+ L E+VK+LI ++++ L A DQL Q A Sbjct: 709 ------PMGRMLFSHDYVFWCGDFNYRID-LPNEEVKELIRQQNWDSLIAGDQLINQKNA 761 Query: 485 KTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK-----------NI 533 VF GF EG++TF PTYKYD SDD+DTSEKCR PAW DR+LW+ + ++ Sbjct: 762 GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDL 821 Query: 534 TQLSYQ-----------------SHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIV 576 S+Q LKTSDH+PV ++ DI + V E + +E++ Sbjct: 822 LNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVI 881 >gi|26190608 synaptojanin 2 [Homo sapiens] Length = 1496 Score = 206 bits (525), Expect = 6e-53 Identities = 133/423 (31%), Positives = 212/423 (50%), Gaps = 63/423 (14%) Query: 229 VSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNG--QSPKECLRL- 285 V+DK +L L + + +++ ++T + R GT+NVNG Q LR Sbjct: 494 VADKGGMLLDSTALLVTPRILKAMTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTA 553 Query: 286 ----WLSNGIQAP------------DVYCVGFQEL-DLSKEAFFFHDTPKEEEWFKAVSE 328 WL + Q D++ VGF+E+ +LS T ++ W + + + Sbjct: 554 ELTDWLLDSPQLSGATDSQDDSSPADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQK 613 Query: 329 GLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQ 388 + +Y + +LVG+ L ++V+ H +I +V +TV TG+ G+ GNKG V IRFQ Sbjct: 614 AISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQ 673 Query: 389 FHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPL--TISNHDVILWLG 446 FH+TS C + SHL A + + RN+DYK+I ++ F P+ + +HD + W G Sbjct: 674 FHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCF--------PMGRNVFSHDYVFWCG 725 Query: 447 DLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDT 506 D NYRI +L E+V ++ +D++ L +DQL++Q ++ +F+ F EG + F PTYKYD Sbjct: 726 DFNYRI-DLTYEEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDV 784 Query: 507 GSDDWDTSEKCRAPAWCDRILWKGK-----------NITQ-----------------LSY 538 GS +DTS+KCR PAW DR+LW K N+ L Y Sbjct: 785 GSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQY 844 Query: 539 QSHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVR---SLDKMENANIPSVSL-SK 594 L+ SDH+PV ++ ++ V+ V+ + +E+ LD N+ S +L K Sbjct: 845 YGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSFQGPLDATVVVNLQSPTLEEK 904 Query: 595 REF 597 EF Sbjct: 905 NEF 907 >gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A [Homo sapiens] Length = 638 Score = 186 bits (471), Expect = 1e-46 Identities = 107/308 (34%), Positives = 161/308 (52%), Gaps = 30/308 (9%) Query: 271 TYNVNGQSPKE----CLRLWLSNGIQAPDVYCVGFQELD--LSKEAFFFHDTPKEEEWFK 324 T+NV P + L L + D+ +G QE++ L+K D ++W + Sbjct: 61 TWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKR---LKDALFTDQWSE 117 Query: 325 AVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVA 384 + L P + V +R+ G++LLL+ K H ++ +V+ + TG+ G GNKGGV+ Sbjct: 118 LFMDALGP-FNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKGGVS 176 Query: 385 IRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILW 444 +R +C +N HL AH+++ E+R +++ I S QF P I +HD++ W Sbjct: 177 VRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQ----GILDHDLVFW 232 Query: 445 LGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKY 504 GDLN+RIE D+ VK I+ L+ DQL + + +GF EG L F PT+K+ Sbjct: 233 FGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPTFKF 292 Query: 505 DTGSDDWDTSEKCRAPAWCDRILWKGK----------------NITQLSYQSHMALKTSD 548 D G++ +DTS K R PAW DRILWK K +TQ SY+SHM SD Sbjct: 293 DVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYTVSD 352 Query: 549 HKPVSSVF 556 HKPV++ F Sbjct: 353 HKPVAAQF 360 >gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo sapiens] Length = 448 Score = 179 bits (453), Expect = 1e-44 Identities = 109/310 (35%), Positives = 163/310 (52%), Gaps = 25/310 (8%) Query: 271 TYNVNGQSPKECLR--LWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSE 328 T+NV +P L L L+N D+Y +G QEL+ S D + W + + Sbjct: 20 TWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELN-SGIISLLSDAAFNDSWSSFLMD 78 Query: 329 GLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQ 388 L P + KV +R+ GI+LL++ K +H YI + ++ TG+ G GNKGGV I + Sbjct: 79 VLSP-LSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLK 137 Query: 389 FHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDL 448 + + ++N HL HI +R + + I MQ C+ +P I +HD+I+W GD+ Sbjct: 138 LYGYYVSIINCHLPPHISNNYQRLEHFDRILE-MQNCE-GRDIP--NILDHDLIIWFGDM 193 Query: 449 NYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGS 508 N+RIE+ + V++ I+ + + L+ DQL I + F EG L F PTYK+D S Sbjct: 194 NFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNS 253 Query: 509 DDWDTSEKCRAPAWCDRILWKGK-----------------NITQLSYQSHMALKTSDHKP 551 +D+DTSEK R PAW DRILW+ K +++ Y SHM SDHKP Sbjct: 254 NDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKP 313 Query: 552 VSSVFDIGVR 561 VS FD+ ++ Sbjct: 314 VSGTFDLELK 323 >gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo sapiens] Length = 372 Score = 165 bits (418), Expect = 2e-40 Identities = 90/243 (37%), Positives = 135/243 (55%), Gaps = 21/243 (8%) Query: 336 YAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSIC 395 + KV +R+ GI+LL++ K +H YI + ++ TG+ G GNKGGV I + + + Sbjct: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68 Query: 396 VVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEEL 455 ++N HL HI +R + + I MQ C+ +P I +HD+I+W GD+N+RIE+ Sbjct: 69 IINCHLPPHISNNYQRLEHFDRILE-MQNCE-GRDIP--NILDHDLIIWFGDMNFRIEDF 124 Query: 456 DVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSE 515 + V++ I+ + + L+ DQL I + F EG L F PTYK+D S+D+DTSE Sbjct: 125 GLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSE 184 Query: 516 KCRAPAWCDRILWKGK-----------------NITQLSYQSHMALKTSDHKPVSSVFDI 558 K R PAW DRILW+ K +++ Y SHM SDHKPVS FD+ Sbjct: 185 KKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDL 244 Query: 559 GVR 561 ++ Sbjct: 245 ELK 247 >gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo sapiens] Length = 372 Score = 165 bits (418), Expect = 2e-40 Identities = 90/243 (37%), Positives = 135/243 (55%), Gaps = 21/243 (8%) Query: 336 YAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSIC 395 + KV +R+ GI+LL++ K +H YI + ++ TG+ G GNKGGV I + + + Sbjct: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68 Query: 396 VVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEEL 455 ++N HL HI +R + + I MQ C+ +P I +HD+I+W GD+N+RIE+ Sbjct: 69 IINCHLPPHISNNYQRLEHFDRILE-MQNCE-GRDIP--NILDHDLIIWFGDMNFRIEDF 124 Query: 456 DVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSE 515 + V++ I+ + + L+ DQL I + F EG L F PTYK+D S+D+DTSE Sbjct: 125 GLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSE 184 Query: 516 KCRAPAWCDRILWKGK-----------------NITQLSYQSHMALKTSDHKPVSSVFDI 558 K R PAW DRILW+ K +++ Y SHM SDHKPVS FD+ Sbjct: 185 KKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDL 244 Query: 559 GVR 561 ++ Sbjct: 245 ELK 247 >gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens] Length = 1258 Score = 161 bits (407), Expect = 3e-39 Identities = 111/334 (33%), Positives = 158/334 (47%), Gaps = 43/334 (12%) Query: 251 HLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNG----------IQAP-DVYCV 299 H Q E D + F GT+N+ P + + W ++ + P D+Y Sbjct: 415 HSKQDEPDMISV-----FIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVF 469 Query: 300 GFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHP--DAKYAKVKLIRLVGIMLLLYVKQEH 357 G QE + + EW + GL D Y + + L I + + VK EH Sbjct: 470 GTQENSVG-----------DREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEH 518 Query: 358 AAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKD 417 IS V +V TGI +GNKG V + F F+ TS VN HL + E+ RRNQ+Y D Sbjct: 519 ENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLD 578 Query: 418 ICSRMQFCQPDPSLPPLTIS-NHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYD 476 I + D L IS + W GDLNYR+ ++D++++ I K+F+ L D Sbjct: 579 ILRLLSL--GDRQLNAFDISLRFTHLFWFGDLNYRL-DMDIQEILNYISRKEFEPLLRVD 635 Query: 477 QLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDD---W----DTSEKCRAPAWCDRILWK 529 QL ++ VF F+E E++F PTY+Y+ GS D W T + P+WCDRILWK Sbjct: 636 QLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWK 695 Query: 530 GKNITQL---SYQSHMALKTSDHKPVSSVFDIGV 560 T + SY + TSDH PV F++GV Sbjct: 696 SYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGV 729 >gi|40254823 SH2 containing inositol phosphatase isoform b [Homo sapiens] Length = 1188 Score = 152 bits (385), Expect = 1e-36 Identities = 106/336 (31%), Positives = 160/336 (47%), Gaps = 44/336 (13%) Query: 251 HLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAP-----------DVYCV 299 H Q E D I F GT+N+ P + + W + Q D+Y + Sbjct: 394 HSEQPEPDMITI-----FIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVI 448 Query: 300 GFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHP--DAKYAKVKLIRLVGIMLLLYVKQEH 357 G QE LS E+EW + + L + V + L I +++ K EH Sbjct: 449 GTQEDPLS-----------EKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEH 497 Query: 358 AAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKD 417 IS + + V TGI +GNKG V + F F+ TS+ VNSHL + E+ RRNQ+Y + Sbjct: 498 ENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMN 557 Query: 418 ICSRMQFCQPDPSLPPLTISNHDV-ILWLGDLNYRIE--ELDVEKVKKLIEEKDFQMLYA 474 I + D L P I++ + W GDLNYR++ + E + + I+++ + L + Sbjct: 558 ILRFLAL--GDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLS 615 Query: 475 YDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDD-------WDTSEKCRAPAWCDRIL 527 +DQL + + VF F E E+TF PTY+++ + D T K P+WCDR+L Sbjct: 616 HDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVL 675 Query: 528 WKGKNITQL---SYQSHMALKTSDHKPVSSVFDIGV 560 WK + + SY S + TSDH PV + F+ GV Sbjct: 676 WKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGV 711 >gi|64085167 SH2 containing inositol phosphatase isoform a [Homo sapiens] Length = 1189 Score = 152 bits (385), Expect = 1e-36 Identities = 106/336 (31%), Positives = 160/336 (47%), Gaps = 44/336 (13%) Query: 251 HLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAP-----------DVYCV 299 H Q E D I F GT+N+ P + + W + Q D+Y + Sbjct: 395 HSEQPEPDMITI-----FIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVI 449 Query: 300 GFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHP--DAKYAKVKLIRLVGIMLLLYVKQEH 357 G QE LS E+EW + + L + V + L I +++ K EH Sbjct: 450 GTQEDPLS-----------EKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEH 498 Query: 358 AAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKD 417 IS + + V TGI +GNKG V + F F+ TS+ VNSHL + E+ RRNQ+Y + Sbjct: 499 ENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMN 558 Query: 418 ICSRMQFCQPDPSLPPLTISNHDV-ILWLGDLNYRIE--ELDVEKVKKLIEEKDFQMLYA 474 I + D L P I++ + W GDLNYR++ + E + + I+++ + L + Sbjct: 559 ILRFLAL--GDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLS 616 Query: 475 YDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDD-------WDTSEKCRAPAWCDRIL 527 +DQL + + VF F E E+TF PTY+++ + D T K P+WCDR+L Sbjct: 617 HDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVL 676 Query: 528 WKGKNITQL---SYQSHMALKTSDHKPVSSVFDIGV 560 WK + + SY S + TSDH PV + F+ GV Sbjct: 677 WKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGV 712 >gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] Length = 644 Score = 127 bits (319), Expect = 5e-29 Identities = 91/321 (28%), Positives = 148/321 (46%), Gaps = 31/321 (9%) Query: 263 QNFRFFAGTYNVNGQS---PKECLRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKE 319 +N F T+N+ GQ P L + A D+Y +G QE Sbjct: 297 RNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQE-----------GCSDR 345 Query: 320 EEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGN 379 EW + E L P Y + + + L+++++ + SEVE TV T I+ ++ Sbjct: 346 REWETRLQETLGPH--YVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKT 403 Query: 380 KGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNH 439 KG + I F F TS + SH + + R DY + + P P S Sbjct: 404 KGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAA 463 Query: 440 DV------ILWLGDLNYRIEE----LDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFE 489 DV + W GD N+R+ +D + L+ D L +DQL ++ ++F+ Sbjct: 464 DVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVV--DVPALLQHDQLIREMRKGSIFK 521 Query: 490 GFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK---NITQLSYQSHMALKT 546 GF E ++ F P+YK+D G D +D++ K R P++ DR+L++ + +I +SY S +KT Sbjct: 522 GFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKT 581 Query: 547 SDHKPVSSVFDIGVRVVNDEL 567 SDH+PV +F + VR D + Sbjct: 582 SDHRPVYGLFRVKVRPGRDNI 602 >gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sapiens] Length = 653 Score = 73.9 bits (180), Expect = 6e-13 Identities = 45/140 (32%), Positives = 75/140 (53%), Gaps = 12/140 (8%) Query: 757 VDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASN--HSVAEALLLFLESLP 814 VD++ + +++E LF+ PG + + ++D D G + ++ H+VA L L+L LP Sbjct: 65 VDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELP 124 Query: 815 EPVICYSTYHNCLEC---------SGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNS 865 EPVI Y+ Y + L C +G +KQV +LP+ + N+ Y+ FL E+ S Sbjct: 125 EPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQV-KSLPVVNYNLLKYICRFLDEVQSYS 183 Query: 866 AKNHLDENILASIFGSLLLR 885 N + LA++FG +LR Sbjct: 184 GVNKMSVQNLATVFGPNILR 203 >gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sapiens] Length = 655 Score = 73.9 bits (180), Expect = 6e-13 Identities = 45/140 (32%), Positives = 75/140 (53%), Gaps = 12/140 (8%) Query: 757 VDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASN--HSVAEALLLFLESLP 814 VD++ + +++E LF+ PG + + ++D D G + ++ H+VA L L+L LP Sbjct: 67 VDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELP 126 Query: 815 EPVICYSTYHNCLEC---------SGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNS 865 EPVI Y+ Y + L C +G +KQV +LP+ + N+ Y+ FL E+ S Sbjct: 127 EPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQV-KSLPVVNYNLLKYICRFLDEVQSYS 185 Query: 866 AKNHLDENILASIFGSLLLR 885 N + LA++FG +LR Sbjct: 186 GVNKMSVQNLATVFGPNILR 205 >gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sapiens] Length = 748 Score = 73.9 bits (180), Expect = 6e-13 Identities = 45/140 (32%), Positives = 75/140 (53%), Gaps = 12/140 (8%) Query: 757 VDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASN--HSVAEALLLFLESLP 814 VD++ + +++E LF+ PG + + ++D D G + ++ H+VA L L+L LP Sbjct: 160 VDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELP 219 Query: 815 EPVICYSTYHNCLEC---------SGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNS 865 EPVI Y+ Y + L C +G +KQV +LP+ + N+ Y+ FL E+ S Sbjct: 220 EPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQV-KSLPVVNYNLLKYICRFLDEVQSYS 278 Query: 866 AKNHLDENILASIFGSLLLR 885 N + LA++FG +LR Sbjct: 279 GVNKMSVQNLATVFGPNILR 298 >gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] Length = 698 Score = 68.9 bits (167), Expect = 2e-11 Identities = 46/151 (30%), Positives = 74/151 (49%), Gaps = 12/151 (7%) Query: 746 PMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGM--IDNLSASNHSVA 803 P P + VD++ + +E LF+ PG + ++D D G + + + H+VA Sbjct: 169 PRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVA 228 Query: 804 EALLLFLESLPEPVICYSTYHNCLECS---------GNYTASKQVISTLPIFHKNVFHYL 854 L L+L LPEPV+ ++ Y + L C+ G +KQV S LP + N+ Y+ Sbjct: 229 SLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQV-SNLPQANYNLLRYI 287 Query: 855 MAFLRELLKNSAKNHLDENILASIFGSLLLR 885 FL E+ S N + LA++FG +LR Sbjct: 288 CKFLDEVQAYSNVNKMSVQNLATVFGPNILR 318 >gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sapiens] Length = 645 Score = 62.8 bits (151), Expect = 1e-09 Identities = 41/151 (27%), Positives = 72/151 (47%), Gaps = 10/151 (6%) Query: 746 PMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASN--HSVA 803 P +P + +++ + +E +F+ PG + + +RD D G + H+VA Sbjct: 173 PHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVA 232 Query: 804 EALLLFLESLPEPVICYSTYHNCLECSGNYTASK--------QVISTLPIFHKNVFHYLM 855 L L+L LPEPV+ +S Y L C A + + +S LP + ++ Y+ Sbjct: 233 SLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYIC 292 Query: 856 AFLRELLKNSAKNHLDENILASIFGSLLLRN 886 FL E+ N A N + + LA++ G L+R+ Sbjct: 293 RFLHEIQLNCAVNKMSVDNLATVIGVNLIRS 323 >gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapiens] Length = 638 Score = 62.8 bits (151), Expect = 1e-09 Identities = 41/151 (27%), Positives = 72/151 (47%), Gaps = 10/151 (6%) Query: 746 PMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASN--HSVA 803 P +P + +++ + +E +F+ PG + + +RD D G + H+VA Sbjct: 166 PHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVA 225 Query: 804 EALLLFLESLPEPVICYSTYHNCLECSGNYTASK--------QVISTLPIFHKNVFHYLM 855 L L+L LPEPV+ +S Y L C A + + +S LP + ++ Y+ Sbjct: 226 SLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYIC 285 Query: 856 AFLRELLKNSAKNHLDENILASIFGSLLLRN 886 FL E+ N A N + + LA++ G L+R+ Sbjct: 286 RFLHEIQLNCAVNKMSVDNLATVIGVNLIRS 316 >gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] Length = 555 Score = 59.3 bits (142), Expect = 2e-08 Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 7/143 (4%) Query: 749 IPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLS--ASNHSVAEAL 806 IP L V YL ++ E LF++ I+ + G N H A L Sbjct: 331 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVIL 390 Query: 807 LLFLESLPEPVICYSTYHN-----CLECSGNYTASKQVISTLPIFHKNVFHYLMAFLREL 861 FL LP+P++ + Y C+E S T +Q++ +LP + V YLM FL + Sbjct: 391 KTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAV 450 Query: 862 LKNSAKNHLDENILASIFGSLLL 884 + S N ++ + LA +FG L+ Sbjct: 451 SRESIFNKMNSSNLACVFGLNLI 473 >gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapiens] Length = 433 Score = 59.3 bits (142), Expect = 2e-08 Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 7/143 (4%) Query: 749 IPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLS--ASNHSVAEAL 806 IP L V YL ++ E LF++ I+ + G N H A L Sbjct: 209 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVIL 268 Query: 807 LLFLESLPEPVICYSTYHN-----CLECSGNYTASKQVISTLPIFHKNVFHYLMAFLREL 861 FL LP+P++ + Y C+E S T +Q++ +LP + V YLM FL + Sbjct: 269 KTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAV 328 Query: 862 LKNSAKNHLDENILASIFGSLLL 884 + S N ++ + LA +FG L+ Sbjct: 329 SRESIFNKMNSSNLACVFGLNLI 351 >gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapiens] Length = 464 Score = 59.3 bits (142), Expect = 2e-08 Identities = 41/143 (28%), Positives = 64/143 (44%), Gaps = 7/143 (4%) Query: 749 IPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLS--ASNHSVAEAL 806 IP L V YL ++ E LF++ I+ + G N H A L Sbjct: 240 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVIL 299 Query: 807 LLFLESLPEPVICYSTYHN-----CLECSGNYTASKQVISTLPIFHKNVFHYLMAFLREL 861 FL LP+P++ + Y C+E S T +Q++ +LP + V YLM FL + Sbjct: 300 KTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAV 359 Query: 862 LKNSAKNHLDENILASIFGSLLL 884 + S N ++ + LA +FG L+ Sbjct: 360 SRESIFNKMNSSNLACVFGLNLI 382 >gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a [Homo sapiens] Length = 1071 Score = 57.4 bits (137), Expect = 6e-08 Identities = 42/161 (26%), Positives = 72/161 (44%), Gaps = 12/161 (7%) Query: 744 DSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNH--- 800 DS IP + + ++ R+ +Q E +F+ G + E I++ + G D L+ + Sbjct: 499 DSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGE-DPLAGDQNDHD 557 Query: 801 --SVAEALLLFLESLPEPVICYSTYHNCLEC------SGNYTASKQVISTLPIFHKNVFH 852 S+A L L+ L P+ +H+ + C ++V+ LP + Sbjct: 558 MDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMR 617 Query: 853 YLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAGHQKL 893 YL AFL L + S +N +D LA FG L+ P GH ++ Sbjct: 618 YLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQV 658 >gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b [Homo sapiens] Length = 836 Score = 57.4 bits (137), Expect = 6e-08 Identities = 42/161 (26%), Positives = 72/161 (44%), Gaps = 12/161 (7%) Query: 744 DSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNH--- 800 DS IP + + ++ R+ +Q E +F+ G + E I++ + G D L+ + Sbjct: 499 DSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGE-DPLAGDQNDHD 557 Query: 801 --SVAEALLLFLESLPEPVICYSTYHNCLEC------SGNYTASKQVISTLPIFHKNVFH 852 S+A L L+ L P+ +H+ + C ++V+ LP + Sbjct: 558 MDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMR 617 Query: 853 YLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAGHQKL 893 YL AFL L + S +N +D LA FG L+ P GH ++ Sbjct: 618 YLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQV 658 >gi|56119110 family with sequence similarity 13, member A1 isoform a [Homo sapiens] Length = 1023 Score = 55.8 bits (133), Expect = 2e-07 Identities = 40/149 (26%), Positives = 71/149 (47%), Gaps = 8/149 (5%) Query: 749 IPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNH--SVAEAL 806 IP +W +V+YL ++ + QE LF+ G E +R ++G+ L S A L Sbjct: 58 IPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLL 117 Query: 807 LLFLESLPEPVICYSTYHNCLECSGN------YTASKQVISTLPIFHKNVFHYLMAFLRE 860 LFL LP+ +I + ++ + ++ + +I LP H + YL FL + Sbjct: 118 KLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKELPDTHYCLLKYLCQFLTK 177 Query: 861 LLKNSAKNHLDENILASIFGSLLLRNPAG 889 + K+ +N ++ + LA++FG P G Sbjct: 178 VAKHHVQNRMNVHNLATVFGPNCFHVPPG 206 >gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b [Homo sapiens] Length = 1075 Score = 53.9 bits (128), Expect = 7e-07 Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%) Query: 744 DSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTG---MIDNLSASN- 799 DS IP + + Y+ +QQ+ +F+ PG + E I++ + G ++D+ + + Sbjct: 490 DSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDI 549 Query: 800 HSVAEALLLFLESLPEPVICYSTYHNCLEC------SGNYTASKQVISTLPIFHKNVFHY 853 +SVA L L+ L P+ + + + + +Q++ TLP V Y Sbjct: 550 NSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRY 609 Query: 854 LMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAG 889 L AFL L + S +N +D LA FG L+ P G Sbjct: 610 LFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDG 645 >gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a [Homo sapiens] Length = 1099 Score = 53.9 bits (128), Expect = 7e-07 Identities = 42/156 (26%), Positives = 72/156 (46%), Gaps = 10/156 (6%) Query: 744 DSPMEIPKELWMMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTG---MIDNLSASN- 799 DS IP + + Y+ +QQ+ +F+ PG + E I++ + G ++D+ + + Sbjct: 514 DSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDI 573 Query: 800 HSVAEALLLFLESLPEPVICYSTYHNCLEC------SGNYTASKQVISTLPIFHKNVFHY 853 +SVA L L+ L P+ + + + + +Q++ TLP V Y Sbjct: 574 NSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVVMRY 633 Query: 854 LMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAG 889 L AFL L + S +N +D LA FG L+ P G Sbjct: 634 LFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDG 669 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,516,996 Number of Sequences: 37866 Number of extensions: 1661240 Number of successful extensions: 4131 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 50 Number of HSP's successfully gapped in prelim test: 54 Number of HSP's that attempted gapping in prelim test: 3957 Number of HSP's gapped (non-prelim): 132 length of query: 913 length of database: 18,247,518 effective HSP length: 111 effective length of query: 802 effective length of database: 14,044,392 effective search space: 11263602384 effective search space used: 11263602384 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.